KEGG   ORTHOLOGY: K02263
Entry
K02263                      KO                                     

Symbol
COX4
Name
cytochrome c oxidase subunit 4
Pathway
map00190  Oxidative phosphorylation
map01100  Metabolic pathways
map04260  Cardiac muscle contraction
map04714  Thermogenesis
map04932  Non-alcoholic fatty liver disease
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Module
M00154  Cytochrome c oxidase
Disease
H00920  Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis
H01368  Cytochrome c oxidase (COX) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02263  COX4; cytochrome c oxidase subunit 4
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K02263  COX4; cytochrome c oxidase subunit 4
  09159 Environmental adaptation
   04714 Thermogenesis
    K02263  COX4; cytochrome c oxidase subunit 4
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K02263  COX4; cytochrome c oxidase subunit 4
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05012 Parkinson disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05014 Amyotrophic lateral sclerosis
    K02263  COX4; cytochrome c oxidase subunit 4
   05016 Huntington disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05020 Prion disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05022 Pathways of neurodegeneration - multiple diseases
    K02263  COX4; cytochrome c oxidase subunit 4
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K02263  COX4; cytochrome c oxidase subunit 4
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K02263  COX4; cytochrome c oxidase subunit 4
Other DBs
TC: 3.D.4.11 3.D.4.8
Genes
HSA: 1327(COX4I1) 84701(COX4I2)
PTR: 100610650 454391(COX4I1) 469913(COX4I2)
PPS: 100969890 100980404 100992865
GGO: 101135385 101141650 101151536
PON: 100173464(COX4I1) 100448759
NLE: 100584639 100597359
MCC: 693811(COX4I1) 713095(COX4I2)
MCF: 102138538 102139855 102144280
CSAB: 103233412 103248003(COX4I2)
CATY: 105574517 105582233 105582641 105594544
MMU: 12857(Cox4i1) 84682(Cox4i2)
RNO: 29445(Cox4i1) 84683(Cox4i2)
OCU: 100327269(COX4I1) 100345745
CFA: 479623(COX4I1) 485825(COX4I2)
PTG: 102949741 102968374(COX4)
BTA: 281090(COX4I1) 618339(COX4I2)
PSIU: 116744100
ECB: 100053548(COX4I2) 100056171(COX4I1)
GGA: 415826(COX4I2)
PCOC: 116243662
MGP: 100538694
CJO: 107319431
NMEL: 110404583
APLA: 101795065
ACYG: 106049252
TGU: 100222254
LSR: 110474501
SCAN: 103816871
PMOA: 120508110
OTC: 121333975
GFR: 102042855
FAB: 101822066
PHI: 102099643
PMAJ: 107210061
CCAE: 111934424
CCW: 104691910
ETL: 114060815
FPG: 101917805
FCH: 102046687
CLV: 102098410
EGZ: 104133757
NNI: 104023582
ACUN: 113484461
TALA: 104366600
PADL: 103923901
AAM: 106485951
AROW: 112978458
NPD: 112949865
DNE: 112987852
AMJ: 102559681(COX4I2) 102574712
PVT: 110087070
PBI: 103060447
PMUR: 107288246
PGUT: 117670991
GJA: 107123752
XLA: 108719104 108720086 379593(cox4i2.L) 444420(cox4i1.S) 444815(cox4i2.S) 447073
XTR: 100127750 549233(cox4i1) 549699(cox4i2)
DRE: 326975(cox4i1) 393776(cox4i2) 402880(cox4i1l)
IPU: 108256745 108264246(COX41) 108275904(COX42)
TRU: 101062555
SASA: 106562286(COX41) 106566437(COX42) 106572113(COX42) 106572114 106579596(COX42) 106587370(cox41)
CMK: 103175926
BFO: 118418543
BBEL: 109473621
CIN: 113474267
SCLV: 120335674
SPU: 591899
APLC: 110988390
SKO: 100370589
DME: Dmel_CG10396(COX4L) Dmel_CG10664(COX4)
DSI: Dsimw501_GD10371(Dsim_GD10371) Dsimw501_GD24236(Dsim_CoIV)
DAN: 6497264
DVI: 6628299
ACOZ: 120956709
AARA: 120901779
AAG: 5566092
CPII: 120426846
AME: 412396
ACER: 107993638
ALAB: 122718464
BIM: 100744616
BBIF: 117214744
BVK: 117233324
BVAN: 117166689
BTER: 100642567
BPYO: 122568235
CCAL: 108630313
OBB: 114878611
MGEN: 117224773
NMEA: 116428725
CGIG: 122399351
SOC: 105195100
MPHA: 105833355
AEC: 105154189
ACEP: 105622676
PBAR: 105434337
VEM: 105560926
HST: 105186641
DQU: 106741421
CFO: 105257159
FEX: 115237723
LHU: 105671426
PGC: 109853666
OBO: 105284212
PCF: 106784431
PFUC: 122519687
VPS: 122630474
NVI: 100117406(Cox4I1) 100121926
CSOL: 105366826
MDL: 103575685
CGLO: 123266621
AGIF: 122857096
TCA: 655374(Cox4)
ATD: 109595607
NVL: 108563345
HAW: 110374944
API: 100158698
DNX: 107173504
AGS: 114120280
RMD: 113560948
BTAB: 109036682
ZNE: 110830830
CSEC: 111875569
FCD: 110855865
DMK: 116916915
PVM: 113827976
PJA: 122258784
HAME: 121871428
HAZT: 108670074
EAF: 111712406
DSV: 119436024
RSAN: 119373541
RMP: 119177006
VDE: 111248048
VJA: 111264792
DPTE: 113795794
CSCU: 111626617
CEL: CELE_W09C5.8(cox-4)
CBR: CBG_19770
BMY: BM_BM6252(Bma-cox-4)
TSP: Tsp_04478
PCAN: 112553343
GAE: 121388151
CRG: 105347217
MYI: 110453644
PMAX: 117338330
OBI: 106882297
OSN: 115211642
LAK: 106169530
EGL: EGR_03601
NVE: 5518081
EPA: 110232462
ATEN: 116297861
ADF: 107352219
AMIL: 114968883
PDAM: 113685317
SPIS: 111336266
DGT: 114517091
HMG: 100211497
SCE: YIL111W(COX5B) YNL052W(COX5A)
ERC: Ecym_3296
KMX: KLMA_80159(COX5A)
NCS: NCAS_0B06400(NCAS0B06400)
NDI: NDAI_0B03690(NDAI0B03690)
TPF: TPHA_0F01210(TPHA0F01210)
TBL: TBLA_0B05810(TBLA0B05810)
TDL: TDEL_0C04030(TDEL0C04030)
KAF: KAFR_0J01530(KAFR0J01530)
PIC: PICST_77110(COX5a)
CAL: CAALFM_C109030CA(COX5)
SLB: AWJ20_1272 AWJ20_4857(COX5A)
NCR: NCU05457(cya-4)
NTE: NEUTE1DRAFT117482(NEUTE1DRAFT_117482)
MGR: MGG_03188
SSCK: SPSK_01901
MAW: MAC_08051
MAJ: MAA_05317
CMT: CCM_07423
MBE: MBM_05495
ANI: AN2316.2
ANG: ANI_1_1404124(An14g04170)
ABE: ARB_07059
TVE: TRV_05994
PTE: PTT_13891
NPA: UCRNP2_79
SPO: SPCC338.10c(cox5)
CNE: CNK03240
CNB: CNBK0240
TASA: A1Q1_03468
ABP: AGABI1DRAFT116514(COX4)
ABV: AGABI2DRAFT195535(COX4)
SLA: SERLADRAFT_476455(COX4)
MGL: MGL_1993
MRT: MRET_1525
 » show all
Reference
  Authors
Huttemann M, Kadenbach B, Grossman LI
  Title
Mammalian subunit IV isoforms of cytochrome c oxidase.
  Journal
Gene 267:111-23 (2001)
DOI:10.1016/S0378-1119(01)00385-7
  Sequence
[hsa:1327 84701]

DBGET integrated database retrieval system