KEGG   ORTHOLOGY: K02545
Entry
K02545                      KO                                     

Name
mecA
Definition
penicillin-binding protein 2 prime [EC:3.4.16.4]
Pathway
ko00550  Peptidoglycan biosynthesis
ko01100  Metabolic pathways
ko01501  beta-Lactam resistance
Module
M00625  Methicillin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    K02545  mecA; penicillin-binding protein 2 prime
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K02545  mecA; penicillin-binding protein 2 prime
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins
    K02545  mecA; penicillin-binding protein 2 prime
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K02545  mecA; penicillin-binding protein 2 prime
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     K02545  mecA; penicillin-binding protein 2 prime
Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   K02545  mecA; penicillin-binding protein 2 prime
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  beta-Lactam resistance modules
   Methicillin resistance
    K02545  mecA; penicillin-binding protein 2 prime
Other DBs
COG: COG0768
GO: 0008658 0009002
Genes
SAU: SA0038(mecA)
SAV: SAV0041(mecA)
SAW: SAHV_0040(mecA)
SAH: SaurJH1_0029
SAJ: SaurJH9_0029
SAM: MW0031(mecA)
SAR: SAR0039(mecA)
SAC: SACOL0033(mecA)
SAX: USA300HOU_0031(mecA)
SAA: SAUSA300_0032(mecA)
SUU: M013TW_0045(mecA)
SUJ: SAA6159_00031(mecA)
SUK: SAA6008_00039(mecA)
SUZ: MS7_0033(mecA)
SUX: SAEMRSA15_00310(mecA)
SUW: SATW20_00740(mecA)
SUG: SAPIG0042
SUF: SARLGA251_00260(mecA)
SAUS: SA40_0033(mecA)
SAUU: SA957_0040(mecA)
SAUG: SA268_0042(mecA)
SAUZ: SAZ172_0072(mecA)
SAUT: SAI1T1_2000270(mecA)
SAUJ: SAI2T2_1000270(mecA)
SAUK: SAI3T3_1000270(mecA)
SAUQ: SAI4T8_1000270(mecA)
SAUV: SAI7S6_1000270(mecA)
SAUW: SAI5S5_1000270(mecA)
SAUX: SAI6T6_1000270(mecA)
SAUY: SAI8T7_1000270(mecA)
SAUF: X998_0034
SUY: SA2981_0039(mecA)
SAUB: C248_0036(mecA)
SAUM: BN843_630
SAUC: CA347_39(mecA)
SAUR: SABB_01772(pbp)
SAMS: NI36_00210
SER: SERP2521(mecA)
SHA: SH0091(mecA)
SHH: ShL2_00029(mecA)
SSCZ: RN70_00210
MCL: MCCL_plsB0023(mecAm)
MCAK: MCCS_00770
 » show all
Reference
  Authors
Turutoglu H, Hasoksuz M, Ozturk D, Yildirim M, Sagnak S
  Title
Methicillin and aminoglycoside resistance in Staphylococcus aureus isolates from bovine mastitis and sequence analysis of their mecA genes.
  Journal
Vet Res Commun 33:945-56 (2009)
DOI:10.1007/s11259-009-9313-5
  Sequence
[sau:SA0038]

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