KEGG ORTHOLOGY: K02582

ORTHOLOGY: K02582

Entry

K02582                      KO

Symbol

NGFB

Name

nerve growth factor, beta

Pathway

map04010

MAPK signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04020

Calcium signaling pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04210

Apoptosis

map04722

Neurotrophin signaling pathway

map04750

Inflammatory mediator regulation of TRP channels

Disease

H00265

Hereditary sensory and autonomic neuropathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K02582  NGFB; nerve growth factor, beta
   04014 Ras signaling pathway
    K02582  NGFB; nerve growth factor, beta
   04015 Rap1 signaling pathway
    K02582  NGFB; nerve growth factor, beta
   04020 Calcium signaling pathway
    K02582  NGFB; nerve growth factor, beta
   04151 PI3K-Akt signaling pathway
    K02582  NGFB; nerve growth factor, beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K02582  NGFB; nerve growth factor, beta
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K02582  NGFB; nerve growth factor, beta
09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K02582  NGFB; nerve growth factor, beta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K02582  NGFB; nerve growth factor, beta
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K02582  NGFB; nerve growth factor, beta
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K02582  NGFB; nerve growth factor, beta
Chaperones and folding catalysts [BR:ko03110]
Intramolecular chaperones
  Others
   K02582  NGFB; nerve growth factor, beta
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Growth factors (RTK binding)
   K02582  NGFB; nerve growth factor, beta

Genes

HSA:

4803(NGF)

PTR:	469423(NGF)

PPS:	100995667(NGF)

GGO:	101149785(NGF)

PON:	100441497(NGF)

PPYG:

129038909(NGF)

NLE:	100593913(NGF)

HMH:	116468350(NGF)

SSYN:

134734660(NGF)

MCC:	711681(NGF)

MCF:	102132327(NGF)

MTHB:

126930848

MNI:	105479138(NGF)

CSAB:

103224160(NGF)

CATY:

105596338(NGF)

PANU:

100998449(NGF)

TGE:	112608614(NGF)

MLEU:

105554362(NGF)

RRO:	104669070(NGF)

RBB:	108528126(NGF)

TFN:	117075427(NGF)

PTEH:

111549636(NGF)

CANG:

105505307(NGF)

CJC:	100391837(NGF)

SBQ:	101038561(NGF)

CIMI:

108301149(NGF)

ANAN:

105727013(NGF)

CSYR:

103259230(NGF)

MMUR:

105878704(NGF)

LCAT:

123635087(NGF)

PCOQ:

105810582(NGF)

OGA:	100946218(NGF)

MMU:	18049(Ngf)

MCAL:

110291584(Ngf)

MPAH:

110320585(Ngf)

RNO:	310738(Ngf)

MCOC:

116093520(Ngf)

ANU:	117706566(Ngf)

MUN:	110564378(Ngf)

CGE:	100750778(Ngf)

MAUA:

110342135(Ngf)

PROB:

127232874(Ngf)

PLEU:

114698577(Ngf)

MORG:

121438019(Ngf)

MFOT:

126510837

AAMP:

119801207(Ngf)

NGI:	103734944(Ngf)

HGL:	101722226(Ngf)

CPOC:

100733367(Ngf)

CCAN:

109676961(Ngf)

DORD:

105991922(Ngf)

DSP:	122118375(Ngf)

PLOP:

125355459(Ngf)

NCAR:

124958523

MMMA:

107156186(Ngf)

OCU:

103350089

OPI:	101527290(NGF)

TUP:	102501945(NGF)

GVR:	103591972(NGF)

CFA:	403402(NGF)

CLUD:

112664154(NGF)

VVP:	112916832(NGF)

VLG:	121490401(NGF)

NPO:	129501424(NGF)

AML:	100469695(NGF)

UMR:	103669449(NGF)

UAH:	113244387(NGF)

UAR:	123794928(NGF)

ELK:	111143419 111143447

LLV:

125099036

MPUF:

101694006(NGF)

MNP:	132000669(NGF)

MLK:	131810037(NGF)

NVS:	122900366(NGF)

ORO:	101384791(NGF)

EJU:	114207847(NGF)

ZCA:	113936078(NGF)

MLX:	118000488(NGF)

NSU:	110580497(NGF)

LWW:	102746197(NGF)

FCA:	100144611(NGF)

PYU:	121027749(NGF)

PCOO:

112872060(NGF)

PBG:	122480987(NGF)

PVIV:

125174035(NGF)

LRUF:

124516475

PTG:	102961057(NGF)

PPAD:

109272115(NGF)

PUC:

125912209

AJU:

106969645

HHV:	120238779(NGF)

BTA:	281350(NGF)

BOM:	102287477(NGF)

BIU:	109555882(NGF)

BBUB:

102400650(NGF)

BBIS:

104981573(NGF)

CHX:	100862660(NGF)

OAS:	101104540(NGF)

BTAX:

128045179(NGF)

ODA:	120856034(NGF)

CCAD:

122435827(NGF)

MBEZ:

129541318(NGF)

SSC:	100738968(NGF)

CFR:	102511686(NGF)

CBAI:

105079965(NGF)

CDK:	105089623(NGF)

VPC:	102536531(NGF)

BACU:

103002155(NGF)

BMUS:

118889007(NGF)

LVE:	103084220(NGF)

OOR:	101277874(NGF)

DLE:	111179989(NGF)

PCAD:

102988669(NGF)

PSIU:

116754467(NGF)

NASI:

112413081(NGF)

ECB:	100065669(NGF)

EPZ:	103547744(NGF)

EAI:	106835685(NGF)

MYB:	102245962(NGF)

MYD:	102769020(NGF)

MMYO:

118673575(NGF)

MLF:	102427030(NGF)

MDT:	132220343(NGF)

PKL:	118727260(NGF)

EFUS:

103291218(NGF)

MNA:	107545260(NGF)

DRO:	112313781(NGF)

SHON:

118982016(NGF)

AJM:	119041752(NGF)

PDIC:

114488932(NGF)

PHAS:

123804625(NGF)

MMF:	118637713(NGF)

PPAM:

129063964(NGF)

HAI:	109392809(NGF)

RFQ:	117014821(NGF)

PALE:

102885454(NGF)

PGIG:

120585075(NGF)

PVP:	105296475(NGF)

RAY:	107499858(NGF)

MJV:	108386081(NGF)

TOD:	119236301(NGF)

SARA:

101557190(NGF)

SETR:

125997353(NGF)

LAV:	100654499(NGF)

TMU:

101341922

ETF:	101658298(NGF)

DNM:	101442636(NGF)

MDO:	100010246(NGF)

GAS:	123247200(NGF)

SHR:	100930279(NGF)

AFZ:

127559262

PCW:	110219284(NGF)

TVP:	118857251(NGF)

OAA:	100074403(NGF)

GGA:	396466(NGF)

PCOC:

116237016(NGF)

MGP:	100543801(NGF)

CJO:	107324926(NGF)

TPAI:

128087993(NGF)

LMUT:

125684039(NGF)

NMEL:

110388196(NGF)

APLA:

101792805(NGF)

ACYG:

106041304(NGF)

CATA:

118255306(NGF)

AFUL:

116498715(NGF)

TGU:	751997(NGF)

LSR:	110473072(NGF)

SCAN:

103822331(NGF)

PMOA:

120497631(NGF)

OTC:	121345667(NGF)

PRUF:

121349758(NGF)

GFR:	102040631(NGF)

FAB:	101812533(NGF)

OMA:	130263760(NGF)

PHI:	102111404(NGF)

PMAJ:

107214905(NGF)

CCAE:

111939656(NGF)

CCW:	104692415(NGF)

CBRC:

103625273(NGF)

ETL:	114064413(NGF)

ZAB:	102061917(NGF)

ZLE:	135458109(NGF)

ACHL:

103799597(NGF)

SVG:	106850961(NGF)

MMEA:

130578868(NGF)

HRT:	120762826(NGF)

SATI:

136371719(NGF)

FPG:	101920218(NGF)

FCH:	102055637(NGF)

CCRI:

104158773(NGF)

NNT:	104402506(NGF)

SHAB:

115602293(NGF)

ACUN:

113488901(NGF)

TALA:

104365493(NGF)

ACHC:

115334762(NGF)

HALD:

104323303(NGF)

HLE:	104838614(NGF)

AGEN:

126052489

GCL:

127026306

CSTI:

104562588(NGF)

LDI:	104344273(NGF)

MNB:	103777981(NGF)

DPUB:

104296292(NGF)

AVIT:

104271852(NGF)

BRHI:

104501634(NGF)

EGZ:	104126776(NGF)

NNI:	104010337(NGF)

PCRI:

104038527(NGF)

PCAO:

104050661(NGF)

PADL:

103923574(NGF)

AFOR:

103893547(NGF)

FGA:	104078792(NGF)

GSTE:

104258330(NGF)

CLV:	102097714(NGF)

MUI:	104543203(NGF)

PGUU:

104462031(NGF)

PLET:

104616993(NGF)

EHS:	104506932(NGF)

CMAC:

104483239(NGF)

CUCA:

104067075(NGF)

TEO:	104383170(NGF)

BREG:

104639125(NGF)

OHA:	104333528(NGF)

ACAR:

104532447(NGF)

CPEA:

104392598(NGF)

CVF:	104289530(NGF)

RTD:	128900229(NGF)

AAM:	106485254(NGF)

AROW:

112971631(NGF)

NPD:	112951503(NGF)

TGT:	104565070(NGF)

DNE:	112993689(NGF)

SCAM:

104142361(NGF)

ASN:	102380366(NGF)

AMJ:	102568830(NGF)

CPOO:

109317843(NGF)

GGN:	109295335(NGF)

PSS:	102451252(NGF)

CMY:	102944320(NGF)

CCAY:

125625211(NGF)

DCC:	119846409(NGF)

CPIC:

101952420(NGF)

TST:	117875734(NGF)

CABI:

116826036(NGF)

MRV:	120402881(NGF)

ACS:	100553574(ngf)

ASAO:

132773331(NGF)

PVT:	110072378(NGF)

SUND:

121928752(NGF)

PBI:	103057660(NGF)

PMUR:

107284057(NGF)

CTIG:

120314141(NGF)

TSR:	106539191(NGF)

PGUT:

117663779(NGF)

APRI:

131196039(NGF)

PTEX:

113444273(NGF)

NSS:	113420784(NGF)

VKO:	123021257(NGF)

PMUA:

114599408(NGF)

PRAF:

128416221(NGF)

ZVI:	118089037(NGF)

HCG:	128321963(NGF)

GJA:	107107944(NGF)

STOW:

125433031 125433970

EMC:	129330685(NGF)

XLA:	108708058(ngf.L) 108709389(ngf.S)

XTR:	100170161(ngf)

NPR:	108795094(NGF)

RTEM:

120927008(NGF)

BBUF:

120993328(NGF)

BGAR:

122932020(NGF)

MUO:	115481731(NGF)

GSH:	117347069(NGF)

DRE:	30270(ngfa) 58133(ngfb)

SRX:	107708055 107708095 107709229 107729735 107735269

SANH:

107666043 107673522 107685837 107696968

SGH:	107554201 107554210 107566067 107596860

CCAR:

109068037 109072067 109091743 109104926 109105553

CAUA:

113041011 113050282 113094066 113105115

CGIB:

127944557 127959148 128011542 128015921

PTET:

122328492(ngfa) 122346605(ngfb)

LROH:

127154738(ngfa) 127167070(ngfb)

OMC:	131532211(ngfa) 131542543(ngfb)

PPRM:

120485513(ngfa) 120493890(ngfb)

RKG:	130084368(ngfa) 130103999(ngfb)

MAMB:

125260099(ngfa) 125273541(ngfb)

CIDE:

127505462 127514744

CERY:

137009571(ngfa) 137011506(ngfb)

MASI:

127418947 127419730 127445965 127449361

TROS:

130545500(ngfa) 130557015(ngfb)

TDW:	130409467(ngfa) 130425183(ngfb)

MANU:

129431453(ngfa) 129450174(ngfb)

IPU:	108271566(ngfb) 108276493(ngfa)

IFU:	128615058(ngfb) 128619362(ngfa)

PHYP:

113533487(ngf) 113545633

SMEO:

124388749(ngfb) 124398644(ngfa)

TFD:	113642780(ngfb) 113650714(ngfa)

TVC:	132843961(ngfb) 132862089(ngfa)

TRN:	134316265(ngfb) 134333229(ngfa)

AMEX:

103030601(ngfa) 103031633(ngfb)

CMAO:

118807564(ngfb) 118823119(ngfa)

EEE:	113587808 113589593

CHAR:

105906386(ngfa) 105909845(ngfb)

TRU:	101070577 101076370

TFS:	130524823(ngfb) 130530603

TNG:	GSTEN00027982G001 GSTEN00033889G001

LCO:	104931860 109136629

NCC:	104941543(ngf) 104950112

TBEN:

117489784(ngfb) 117494080(ngfa)

CGOB:

115008416 115010778 115010779

PGEO:

117446265(ngfb) 117450088(ngfa)

GACU:

117539576(ngfb) 117545995

EMAC:

134867334(ngfa) 134883265(ngfb)

ELY:	117256545(ngfb) 117257751(ngfa)

EFO:	125890463(ngfb) 125892401

PLEP:

121947378(ngfa) 121959310(ngfb)

SLUC:

116051591(ngfb) 116058571(ngfa)

ECRA:

117943932(ngfb) 117947652(ngfa)

ESP:	116688351 116692451

PFLV:

114554921(ngf) 114558351

GAT:	120829856(ngfa) 120835834(ngfb)

PPUG:

119223149(ngfa) 119230026(ngfb)

AFB:	129099308(ngfa) 129106371(ngfb)

CLUM:

117731293(ngfb) 117733451(ngfa)

PSWI:

130199375(ngfa) 130208760(ngfb)

MSAM:

119886942(ngfb) 119906156(ngfa)

SCHU:

122882429(ngfa) 122884627(ngfb)

CUD:	121507216(ngfb) 121518092(ngfa)

ALAT:

119021504(ngfb) 119023601(ngfa)

MZE:	101468558 101486340

ONL:	100692989 100696124

OAU:	116317766(ngfb) 116330803(ngfa)

OLA:	101157368 101164147

OML:	112144593(ngfb) 112159198(ngfa)

CSAI:

133449295(ngfb) 133456461(ngfa)

XMA:	102232475 102232576

XCO:	114136304 114152283

XHE:	116709708 116722050

PRET:

103464694 103467432 103471103

PFOR:

103134588 103144550 103149637

PLAI:

106947080 106954198 106963075

PMEI:

106920990 106925564 106929556

GAF:	122832086 122833493(ngfb)

PPRL:

129372351(ngfa) 129372835(ngfb)

CVG:	107087023 107101302

CTUL:

119779015(ngfb) 119784351

GMU:	124857129(ngfb) 124865727(ngfa)

NFU:	107385046 107390964

KMR:	108231487(ngfb) 108235167(ngfa)

ALIM:

106517676 106524130

NWH:	119412452(ngfb) 119416918

AOCE:

111573866 111579897

MCEP:

125007264(ngfB) 125011841(ngfA)

CSEM:

103384424 103386552

POV:	109635098 109635456(ngf)

SSEN:

122767822(ngfb) 122777529 122777552

HHIP:

117761064(ngfb) 117764022(ngfa)

HSP:	118104764(ngfb) 118110421(ngfa)

PPLT:

128442335(ngfa) 128458923(ngfb)

SMAU:

118309316(ngfb) 118316706(ngfa)

LCF:	108873577 108877951(ngfa)

SDU:	111218944 111219495

SLAL:

111648761 111662357 111669009

XGL:	120803506(ngfa) 120807558(ngfb)

HCQ:	109506954 109528249

SSCV:

125976752 125988956

SBIA:

133493969(ngfa) 133507894(ngfb)

PEE:	133398716(ngfa) 133409141(ngfb)

PTAO:

133483201(ngfb) 133487867(ngfa)

BPEC:

110164886 110174814

MALB:

109969589 109974568

BSPL:

114855121(ngfb) 114858453(ngfa)

SJO:	128355934(ngfb) 128357875(ngfa)

SASA:

106566077 106566305 106582728 106592688

STRU:

115151005 115166403 115207427

OTW:	112221249 112222421 112237544(ngfa) 112255445(ngfb)

OMY:	110515522 110527108(ngfb) 110533299(ngfa) 118940497

OGO:	124004234 124021009(ngfb) 124032420 124045444

ONE:	115118265 115145364

OKI:	109865528 109877768 109882837 109890148

OKE:	118379730 118389443 118399735(ngfb) 127912331 127912332 127913048(ngfa)

SALP:

111970599 112069023 112073500

SNH:	120024336 120039573 120061462 120064924

CCLU:

121555479 121555826 121575824 121578716

ELS:	105007566 105028952

SFM:	108918378(ngf) 108939188

PKI:	111855250 111856976

AANG:

118208607(ngfa) 118211653

LOC:	102692738(ngf)

PSPA:

121299458 121299741

ARUT:

117433907 117965946

PSEX:

120526256(ngfb)

LCM:	102364322(NGF)

RTP:

CPLA:

HOC:

SKO:

PJA:

PCHN:

PCLA:

MMER:

Reference

PMID:16939974

Authors

Reichardt LF

Title

Neurotrophin-regulated signalling pathways.

Journal

Philos Trans R Soc Lond B Biol Sci 361:1545-64 (2006)
DOI:10.1098/rstb.2006.1894

Reference

PMID:3670305

Authors

Selby MJ, Edwards R, Sharp F, Rutter WJ

Title

Mouse nerve growth factor gene: structure and expression.

Journal

Mol Cell Biol 7:3057-64 (1987)
DOI:10.1128/MCB.7.9.3057

Sequence

[mmu:18049]

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (2)   
   KEGG DRUG (2)   
Gene (649)   
   KEGG GENES (565)   
   KEGG MGENES (44)   
   RefGene (39)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (675)   

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