KEGG ORTHOLOGY: K02620

ORTHOLOGY: K02620

Entry

K02620                      KO

Symbol

TCF7, TCF-1

Name

transcription factor 7

Pathway

map04310

Wnt signaling pathway

map04390

Hippo signaling pathway

map04519

Cadherin signaling

map04520

Adherens junction

map04550

Signaling pathways regulating pluripotency of stem cells

map04916

Melanogenesis

map04934

Cushing syndrome

map04936

Alcoholic liver disease

map05132

Salmonella infection

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05200

Pathways in cancer

map05210

Colorectal cancer

map05213

Endometrial cancer

map05215

Prostate cancer

map05216

Thyroid cancer

map05217

Basal cell carcinoma

map05221

Acute myeloid leukemia

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05412

Arrhythmogenic right ventricular cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
   04390 Hippo signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    K02620  TCF7, TCF-1; transcription factor 7
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K02620  TCF7, TCF-1; transcription factor 7
   04550 Signaling pathways regulating pluripotency of stem cells
    K02620  TCF7, TCF-1; transcription factor 7
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K02620  TCF7, TCF-1; transcription factor 7
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05225 Hepatocellular carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05226 Gastric cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05216 Thyroid cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05221 Acute myeloid leukemia
    K02620  TCF7, TCF-1; transcription factor 7
   05217 Basal cell carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05215 Prostate cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05213 Endometrial cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05224 Breast cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02620  TCF7, TCF-1; transcription factor 7
   05165 Human papillomavirus infection
    K02620  TCF7, TCF-1; transcription factor 7
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K02620  TCF7, TCF-1; transcription factor 7
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K02620  TCF7, TCF-1; transcription factor 7
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K02620  TCF7, TCF-1; transcription factor 7
   04934 Cushing syndrome
    K02620  TCF7, TCF-1; transcription factor 7
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02620  TCF7, TCF-1; transcription factor 7
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K02620  TCF7, TCF-1; transcription factor 7

Genes

HSA:	6932(TCF7)

PTR:	745839(TCF7)

PPS:	100980839(TCF7)

GGO:	101149731(TCF7)

PON:	100461234(TCF7)

PPYG:

129036888(TCF7)

NLE:	100595737(TCF7)

HMH:	116471505(TCF7)

SSYN:

129457838(TCF7)

MCC:	710234(TCF7)

MCF:	102142248(TCF7)

MTHB:

126955989

MNI:	105467144(TCF7)

CSAB:

103244543(TCF7)

CATY:

105599768(TCF7)

PANU:

101024089(TCF7)

TGE:	112626303(TCF7)

MLEU:

105531321(TCF7)

RRO:	104659811(TCF7)

RBB:	108529562(TCF7)

TFN:	117065864(TCF7)

PTEH:

111529175(TCF7)

CANG:

105518212(TCF7)

CJC:	100399154(TCF7)

SBQ:	101029076(TCF7)

CIMI:

108307147(TCF7)

ANAN:

105708982(TCF7)

CSYR:

103268315(TCF7)

MMUR:

105869975(TCF7)

LCAT:

123637773(TCF7)

ERUF:

138393034(TCF7)

PCOQ:

105816027(TCF7)

OGA:	100947392(TCF7)

MMU:	21414(Tcf7)

MCAL:

110304948(Tcf7)

MPAH:

110332085(Tcf7)

RNO:	363595(Tcf7)

MCOC:

116077224(Tcf7)

ANU:	117710774(Tcf7)

ASYL:

127695303(Tcf7)

MUN:	110549622(Tcf7)

CGE:	100757390(Tcf7)

MAUA:

101823261(Tcf7)

PROB:

127219310(Tcf7)

PLEU:

114683055(Tcf7)

PMAV:

102905415(Tcf7)

MORG:

121456269(Tcf7)

MFOT:

126510979

AAMP:

119812304(Tcf7)

CNL:	130877513(Tcf7)

NGI:	103729786(Tcf7)

HGL:	101707882(Tcf7)

CPOC:

100712802(Tcf7)

CCAN:

109689465(Tcf7)

DORD:

105996789(Tcf7)

DSP:	122115432(Tcf7)

DMER:

138807914(Tcf7)

PLOP:

125342174(Tcf7)

NCAR:

124986637

SVUL:

306663695(TCF7)

MMMA:

107148128(Tcf7)

ITI:	101967509(Tcf7)

MAVE:

308264856(TCF7)

OCU:

100339216

OPI:	101526730(TCF7)

OCZ:	121150630(TCF7)

TUP:	102484318(TCF7)

GVR:	103592399(TCF7)

CFA:	481506(TCF7)

CLUD:

112650538(TCF7)

VVP:	112917059(TCF7)

VLG:	121495797(TCF7)

NPO:	129494859(TCF7)

AML:	100476528(TCF7)

UMR:	103663815(TCF7)

UAH:	113261735(TCF7)

UAR:	123790349(TCF7)

ELK:

111141244

LLV:

125099902

MPUF:

101678117(TCF7)

MNP:	132028516(TCF7)

MLK:	131832039(TCF7)

NVS:	122891699(TCF7)

MMAQ:

308342980(TCF7)

ORO:	101376237(TCF7)

EJU:	114209512(TCF7)

ZCA:	113928407(TCF7)

MLX:	118016638(TCF7)

MANO:

123856449(TCF7)

NSU:	110590995(TCF7)

LWW:	102733939(TCF7)

FCA:	101098768(TCF7)

PYU:	121010702(TCF7)

PCOO:

112861082(TCF7)

PBG:	122487396(TCF7)

PVIV:

125154231(TCF7)

LRUF:

124515627

LGF:	123603765(TCF7)

AJU:

106984911

PTG:	102957988(TCF7)

PPAD:

109250863(TCF7)

PUC:

125935489

PLEZ:

122217706(TCF7)

HHV:	120238500(TCF7)

CCRU:

144235191(TCF7)

BTA:	782690(TCF7)

BOM:	102266633(TCF7)

BIU:	109562015(TCF7)

BJV:	133251270(TCF7)

BBUB:

102408996(TCF7)

BKE:	129632259(TCF7)

BBIS:

104991933(TCF7)

CHX:	102173736(TCF7)

OAS:	101101980(TCF7)

OCAN:

138441292(TCF7)

BTAX:

128050871(TCF7)

CSUM:

138085852(TCF7)

ODA:	120863661(TCF7)

CCAD:

122439921(TCF7)

MREE:

136167824(TCF7)

OVR:	110146932(TCF7)

MBEZ:

129558296(TCF7)

SSC:	100512951(TCF7)

CFR:	102519063(TCF7)

CBAI:

105082121(TCF7)

CDK:	105090254(TCF7)

VPC:	102537589(TCF7)

BACU:

103018264(TCF7)

BMUS:

118892102(TCF7)

LVE:	103074150(TCF7)

OOR:	101289599(TCF7)

LALB:

132517062(TCF7)

GMF:	115860129(TCF7)

DDP:	132423285(TCF7)

SCOO:

307183721(TCF7)

PCRS:

137221670(TCF7)

DLE:	111182442(TCF7)

PCAD:

102992878(TCF7)

PSIU:

116752164(TCF7)

PPHC:

136119963(TCF7)

NASI:

112399678(TCF7)

HAMP:

307052435(TCF7)

ECB:	100072786(TCF7)

EPZ:	103543120(TCF7)

EAI:	106834657(TCF7)

MYB:	102250528(TCF7)

MYD:	102757003(TCF7)

MMYO:

118657631(TCF7)

MLF:	102433022(TCF7)

MDT:	132235660(TCF7)

MYUM:

139010487(TCF7)

PKL:	118711889(TCF7)

EFUS:

103286726(TCF7)

POTS:

308250352(TCF7)

MNA:	107525397(TCF7)

DRO:	112318180(TCF7)

SHON:

118990084(TCF7)

AJM:	119037608(TCF7)

PDIC:

114509934(TCF7)

PHAS:

123811661(TCF7)

MMF:	118643629(TCF7)

PPAM:

129066685(TCF7)

HAI:	109382635(TCF7)

RFQ:	117017071(TCF7)

RHII:

308491467(TCF7)

PALE:

102885788(TCF7)

PGIG:

120581289(TCF7)

PVP:	105293567(TCF7)

RAY:	107506797(TCF7)

MJV:	108406081(TCF7)

TOD:	119243471(TCF7)

SARA:

101540913(TCF7)

SFUM:

130032858(TCF7)

SETR:

126027752(TCF7)

LAV:	100663559(TCF7)

TMU:

101350837

ETF:	101657040(TCF7)

DNM:	101411457(TCF7)

MDO:	100017589(TCF7)

GAS:	123237636(TCF7)

SHR:	100930141(TCF7)

AFZ:

127549825

PCW:	110211723(TCF7)

TVP:	118841366(TCF7)

PBRV:

138164215(TCF7)

MLAO:

141506624(TCF7)

OAA:	100082332(TCF7)

TACU:

119950320(TCF7)

GGA:	395229(TCF7)

PCOC:

116232216(TCF7)

MGP:	100544924(TCF7)

CJO:	107320225(TCF7)

TPAI:

128083971(TCF7)

LMUT:

125700061(TCF7)

NMEL:

110405287(TCF7)

APLA:

101803610(TCF7)

AACU:

137864034(TCF7)

OJA:	118174009(TCF7)

BCLA:

308449165(TCF7)

ACYG:

106032766(TCF7)

ABRC:

308177760(TCF7)

CATA:

118254957(TCF7)

AFUL:

116495052(TCF7)

TGU:	100221008(TCF7)

LSR:	110481074(TCF7)

VMC:	128814774(TCF7)

VCHA:

128795584(TCF7)

AIB:	137483010(TCF7)

SCAN:

103817470(TCF7)

PMOA:

120498623(TCF7)

OTC:	121332492(TCF7)

PRUF:

121361301(TCF7)

ATRC:

139597662(TCF7)

MATE:

118692088(TCF7)

MAEN:

136563065(TCF7)

GFR:	102036749(TCF7)

FAB:	101820491(TCF7)

OMA:	130258940(TCF7)

PHI:	102110510(TCF7)

PMAJ:

107210639(TCF7)

CCAE:

111935599(TCF7)

CCW:	104683724(TCF7)

CBRC:

103614692(TCF7)

ACOE:

138118058(TCF7)

ETL:	114063910(TCF7)

ZAB:	102061135(TCF7)

ZLE:	135453706(TCF7)

ACHL:

103807821(TCF7)

SVG:	106862626(TCF7)

MMEA:

130576571(TCF7)

HRT:	120759054(TCF7)

SATI:

136367426(TCF7)

CFAI:

136297406(TCF7)

CCIC:

134049701(TCF7)

NNT:

104408659

SHAB:

115615905(TCF7)

POCC:

134173744(TCF7)

FPG:	101919678(TCF7)

FCH:	102058554(TCF7)

FRS:	119151989(TCF7)

ACUN:

113485114(TCF7)

ANOC:

141965028(TCF7)

SURA:

141949686(TCF7)

TALA:

104365223(TCF7)

ACHC:

115334089(TCF7)

HLE:	104839072(TCF7)

AGEN:

126051116

HHAR:

128155054(TCF7)

BBUT:

142044409(TCF7)

GCL:

127021964

CSTI:

104558021(TCF7)

LDI:

104346558

DPUB:

104310141(TCF7)

PPUS:

135185448(TCF7)

IIN:	128973197(TCF7)

AVIT:

104274978(TCF7)

BRHI:

104496022(TCF7)

EGZ:	104133478(TCF7)

NNI:	104012004(TCF7)

PCAO:

104051181(TCF7)

PARX:

142061606(TCF7)

PADL:

103915850(TCF7)

AFOR:

103904439(TCF7)

CBOR:

142088819(TCF7)

CBOY:

140656670(TCF7)

MAME:

142413440(TCF7)

CLV:	102094656(TCF7)

CNIC:

135993821(TCF7)

NMAY:

308045889(TCF7)

MUI:

104543267

PGUU:

104459059

EHS:	104509814(TCF7)

CUCA:

104060926(TCF7)

PCUR:

138727143(TCF7)

TEO:

104383729

GAME:

129212594(TCF7)

OHA:	104338062(TCF7)

ACAR:

104529243

CEUR:

306721457(TCF7)

CPEA:

104386840(TCF7)

CVF:	104292051(TCF7)

RTD:	128915932(TCF7)

CRID:

134521745(TCF7)

LMIC:

141749677(TCF7)

NARQ:

141470569(TCF7)

AAM:	106487174(TCF7)

AROW:

112964702(TCF7)

NPD:	112952974(TCF7)

TGT:

104572832

DNE:	112994146(TCF7)

ASN:	102383175(TCF7)

AMJ:	102576120(TCF7)

CPOO:

109310088(TCF7)

GGN:	109289961(TCF7)

PSS:	102446665(TCF7)

CIZ:	142021376(TCF7)

CMY:	102943166(TCF7)

CCAY:

125641612(TCF7)

LKP:	140915619(TCF7)

NDS:	141991964(TCF7)

DCC:	119860601(TCF7)

CPIC:

101937399(TCF7)

TST:	117882270(TCF7)

EOB:	135883130(TCF7)

CABI:

116826639(TCF7)

MRV:	120370469(TCF7)

EMQ:	137165306(TCF7)

ACS:	100554608(tcf7)

ASAO:

132768881(TCF7)

PVT:	110079405(TCF7)

SUND:

121922739(TCF7)

PBI:	103067042(TCF7)

PMUR:

107294908(TCF7)

CTIG:

120305514(TCF7)

TSR:	106542632(TCF7)

PGUT:

117656083(TCF7)

PCAE:

139312478(TCF7)

PTEX:

113433747(TCF7)

NSS:	113425241(TCF7)

VKO:	123035726(TCF7)

PMUA:

114591268(TCF7)

PRAF:

128407866(TCF7)

ZVI:	118080356(TCF7)

HCG:	128344517(TCF7)

GJA:	107125983(TCF7)

STOW:

125429787(TCF7)

EMC:	129328416(TCF7)

XLA:	398658(tcf7.S)

XTR:	395061(tcf7)

NPR:	108792126(TCF7)

ACAT:

141132419

PADS:

140322410(TCF7)

BBUF:

121009361(TCF7)

BGAR:

122928266(TCF7)

DTC:	141087913(TCF7)

PCOB:

134933474

PWL:	138245534(TCF7)

MUO:	115475827(TCF7)

GSH:	117351675(TCF7)

DRE:	497649(tcf7)

DAES:

130215103(tcf7)

SRX:	107728269 107742437(tcf7)

SANH:

107661683(tcf7) 107692971

SGH:	107557295 107603263

CCAR:

109048020 109067898

CAUA:

113038246 113063835

CGIB:

127941480 127985702

PTET:

122326316(tcf7)

LROH:

127152460(tcf7)

OMC:	131528515(tcf7)

PPRM:

120473621(tcf7)

RKG:	130077508(tcf7)

SCEP:

307144620(tcf7)

MAMB:

125253085(tcf7)

CIDE:

127503210

CERY:

137012083(tcf7)

MASI:

127429142 127430673

TROS:

130570657(tcf7)

TDW:	130408426(tcf7)

MANU:

129423732(tcf7)

PDAB:

135776734(tcf7)

IPU:

108278866

IFU:	128621996(tcf7)

PHYP:

113535749

SMEO:

124397852(tcf7)

TFD:	113646522(tcf7)

TVC:	132860516(tcf7)

CGAR:

128507885(tcf7)

NGRA:

132895327(tcf7)

TRN:	134330139(tcf7)

AMEX:

103045826(tcf7)

CMAO:

118820197(tcf7)

EEE:	113578029(tcf7)

CHAR:

105893198(tcf7)

SPIL:

134079903(tcf7)

ASAD:

121708542(tcf7)

TRU:	101076516(tcf7)

TFS:	130537242(tcf7)

NCC:	104960861(tcf7)

TBEN:

117490735(tcf7)

CGOB:

115018803(tcf7)

PGEO:

117458286(tcf7)

GACU:

117540208(tcf7)

EMAC:

134871756(tcf7) 134876197

ELY:	117268549(tcf7)

EFO:	125898881(tcf7)

PLEP:

121952129(tcf7)

SLUC:

116055911(tcf7) 118493643

SVIT:

144528280(tcf7)

ECRA:

117955094(tcf7)

ESP:	116679407 116700180(tcf7)

PFLV:

114566424(tcf7)

PFLT:

120543862(tcf7)

GAT:	120821561(tcf7)

PPUG:

119215586(tcf7)

AFB:	129113131(tcf7)

CLUM:

117742499(tcf7)

PSWI:

130211081(tcf7)

CANA:

137802965(tcf7)

TBU:	306732865(tcf7)

CVE:	137887039 137888280(tcf7)

MSAM:

119895287(tcf7)

SCHU:

122888511(tcf7)

EARM:

139294957(tcf7)

CUD:	121518698(tcf7)

SPUL:

138596056(tcf7)

LMIX:

132958393 132988170(tcf7)

HTC:	141791511(tcf7)

ALAT:

119014087 119031550(tcf7)

ASTR:

137605908(tcf7)

PKLU:

139212925(tcf7)

LCO:

104924428

AMMM:

307260993(tcf7)

MZE:	101469770(tcf7)

ONL:	100710520(tcf7)

OAU:	116315805(tcf7)

OLA:	101162309(tcf7) 101162335 111947120

OML:	112137216 112142310(tcf7)

CSAI:

133460035(tcf7)

XMA:	102221228(tcf7) 111610761

XCO:	114152465(tcf7) 114157642

XHE:	116728111(tcf7) 116732626

PRET:

103460015(tcf7) 103480959

PFOR:

103155760(tcf7)

PLAI:

106935267(tcf7) 106958964

PMEI:

106910477 106916700(tcf7)

GAF:	122820847 122844686(tcf7)

PPRL:

129373420(tcf7)

CVG:	107085909(tcf7)

CTUL:

119797145 119797952(tcf7)

GMU:	124876424(tcf7) 124880979

NFU:	107378492 107386837(tcf7)

KMR:	108238102(tcf7)

ALIM:

106524564(tcf7) 106532889

NWH:	119420469(tcf7)

LTU:	140279969(tcf7)

MCEP:

125020943(tcf7)

AOCE:

111566135(tcf7)

EJA:	138213651(tcf7)

BFRE:

138632072(tcf7)

LCF:

108893669

CSEM:

103394864(tcf7)

POV:	109635808(tcf7)

SSEN:

122776845 122779518(tcf7)

SSOE:

131458177(tcf7) 131468140

HHIP:

117751920 117771739 117772199 117774284(tcf7)

HSP:	118102942 118121778(tcf7)

PPLT:

128429971 128457663(tcf7)

SMAU:

118300136(tcf7)

SDU:	111234495(tcf7)

SLAL:

111659992(tcf7)

XGL:	120803038(tcf7)

HCQ:	109515640 109531063

SSCV:

125982336(tcf7)

SBIA:

133492132(tcf7)

PEE:	133415647(tcf7)

PTAO:

133467680(tcf7) 133471053 133471449 133489017

ENY:	140360708(tcf7)

MALB:

109966812(tcf7)

BSPL:

114869348(tcf7)

SJO:	128371950(tcf7)

SSCO:

133994542(tcf7)

TTY:	137195891(tcf7)

GMH:	115546617(tcf7)

SASA:

106567524 106603814

STRU:

115148559 115154022

OTW:	112228202 112258094

OMY:	101268913(tcf7) 110537729

OGO:	123999056 124013670

ONE:	115105282 115136184

OKI:	109873359 109892952

OKE:	118389828 118390897

OMM:	135548833(tcf7)

OCLA:

139418039 139420784

SALP:

111979956 112069673

SNH:	120044389(tcf7) 120056778

SFON:

129820815 129868188

CCLU:

121574004 121579234

ELS:

105026693

OEP:	134013922(tcf7)

SFM:	108929645 108934364

PKI:

111839551

AANG:

118236295(tcf7)

AROT:

135262665(tcf7)

CCOG:

133132643(tcf7)

LOC:	102694215(tcf7)

PSPA:

121297274 121324311

ARUT:

117413262 117431552

PSEX:

120542075(tcf7)

LCM:	102350321(TCF7)

CMK:	103183678(tcf7)

CPLA:

122556583(tcf7)

CPUN:

140492018

HOC:	132823436(tcf7)

SCAU:

119965316

LERI:

129701802(tcf7)

HAKA:

140739154(tcf7)

PMRN:

CLEP:

APLN:

VDE:

DFR:

GAE:

MYI:

ATEN:

MCAZ:

MFOO:

HSY:

RES:

CCLM:

Reference

PMID:1569101

Authors

van de Wetering M, Oosterwegel M, Holstege F, Dooyes D, Suijkerbuijk R, Geurts van Kessel A, Clevers H

Title

The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.

Journal

J Biol Chem 267:8530-6 (1992)

Sequence

[hsa:6932]

Reference

PMID:17143293

Authors

Arce L, Yokoyama NN, Waterman ML

Title

Diversity of LEF/TCF action in development and disease.

Journal

Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

Reference

PMID:11477404

Authors

Ioannidis V, Beermann F, Clevers H, Held W

Title

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.

Journal

Nat Immunol 2:691-7 (2001)
DOI:10.1038/90623

Sequence

[mmu:21414]

All links

Gene (143)   
   MGENES (118)   
   RefGene (19)   
   OC (6)   
All databases (143)   

Download RDF

ORTHOLOGY: K04490

Entry

K04490                      KO

Symbol

TCF7L1

Name

transcription factor 7-like 1

Pathway

map04310

Wnt signaling pathway

map04390

Hippo signaling pathway

map04519

Cadherin signaling

map04520

Adherens junction

map04916

Melanogenesis

map04934

Cushing syndrome

map04936

Alcoholic liver disease

map05132

Salmonella infection

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05200

Pathways in cancer

map05210

Colorectal cancer

map05213

Endometrial cancer

map05215

Prostate cancer

map05216

Thyroid cancer

map05217

Basal cell carcinoma

map05221

Acute myeloid leukemia

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05412

Arrhythmogenic right ventricular cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04490  TCF7L1; transcription factor 7-like 1
   04390 Hippo signaling pathway
    K04490  TCF7L1; transcription factor 7-like 1
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    K04490  TCF7L1; transcription factor 7-like 1
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04490  TCF7L1; transcription factor 7-like 1
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04490  TCF7L1; transcription factor 7-like 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04490  TCF7L1; transcription factor 7-like 1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05225 Hepatocellular carcinoma
    K04490  TCF7L1; transcription factor 7-like 1
   05226 Gastric cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05216 Thyroid cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05221 Acute myeloid leukemia
    K04490  TCF7L1; transcription factor 7-like 1
   05217 Basal cell carcinoma
    K04490  TCF7L1; transcription factor 7-like 1
   05215 Prostate cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05213 Endometrial cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05224 Breast cancer
    K04490  TCF7L1; transcription factor 7-like 1
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04490  TCF7L1; transcription factor 7-like 1
   05165 Human papillomavirus infection
    K04490  TCF7L1; transcription factor 7-like 1
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04490  TCF7L1; transcription factor 7-like 1
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04490  TCF7L1; transcription factor 7-like 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04490  TCF7L1; transcription factor 7-like 1
   04934 Cushing syndrome
    K04490  TCF7L1; transcription factor 7-like 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04490  TCF7L1; transcription factor 7-like 1
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04490  TCF7L1; transcription factor 7-like 1

Genes

HSA:	83439(TCF7L1)

PTR:	744526(TCF7L1)

PPS:	100968002(TCF7L1)

GGO:	101151621(TCF7L1)

PON:	100436197(TCF7L1)

PPYG:

129030261(TCF7L1)

NLE:	100601518(TCF7L1)

HMH:	116483590(TCF7L1)

SSYN:

129461823(TCF7L1)

MCC:	694560(TCF7L1)

MCF:	102125513(TCF7L1)

MTHB:

126933391

MNI:	105465371(TCF7L1)

CSAB:

103219950(TCF7L1)

CATY:

105587638(TCF7L1)

PANU:

101017547(TCF7L1)

TGE:	112604528(TCF7L1)

MLEU:

105528862(TCF7L1)

RRO:	104659731(TCF7L1)

RBB:	108542809(TCF7L1)

TFN:	117062119(TCF7L1)

PTEH:

111551134(TCF7L1)

CANG:

105527514(TCF7L1)

CJC:	100403963(TCF7L1)

SBQ:	101033762(TCF7L1)

CIMI:

108295686(TCF7L1)

ANAN:

105707914(TCF7L1)

CSYR:

103266761

MMUR:

105876584(TCF7L1)

LCAT:

123637116(TCF7L1)

ERUF:

138400221(TCF7L1)

PCOQ:

105810284(TCF7L1)

OGA:	100940553(TCF7L1)

MMU:	21415(Tcf7l1)

MCAL:

110296038(Tcf7l1)

MPAH:

110315696(Tcf7l1)

RNO:	312451(Tcf7l1)

MCOC:

116099088(Tcf7l1)

ANU:	117715247(Tcf7l1)

ASYL:

127678793(Tcf7l1)

MUN:	110541202(Tcf7l1)

CGE:	100753225(Tcf7l1)

MAUA:

101839395(Tcf7l1) 121142589

PROB:

127235531(Tcf7l1)

PLEU:

114681591(Tcf7l1)

PMAV:

102910538(Tcf7l1)

MORG:

121437942(Tcf7l1)

MFOT:

126493279

AAMP:

119807723(Tcf7l1)

CNL:	130877295(Tcf7l1)

NGI:	103739783(Tcf7l1)

HGL:	101699909(Tcf7l1)

CPOC:

100731379(Tcf7l1)

CCAN:

109686184(Tcf7l1)

DORD:

106000204(Tcf7l1)

DSP:	122116902(Tcf7l1)

DMER:

138804608(Tcf7l1)

PLOP:

125356229(Tcf7l1)

NCAR:

124963199

SVUL:

306643741(TCF7L1)

MMMA:

107159692(Tcf7l1)

ITI:	101973298(Tcf7l1)

SCIL:

308632107(TCF7L1)

MAVE:

308274209(TCF7L1)

OCU:

100340471

OPI:	101522406(TCF7L1)

OCZ:	121165136(TCF7L1)

TUP:	102481394(TCF7L1)

GVR:	103585949(TCF7L1)

CFA:	612070(TCF7L1)

CLUD:

112664304(TCF7L1)

VVP:	112916685(TCF7L1)

VLG:	121490511(TCF7L1)

NPO:	129510910(TCF7L1)

AML:	100480690(TCF7L1)

UMR:	103671448(TCF7L1)

UAH:	113243231(TCF7L1)

UAR:	123799645(TCF7L1)

ELK:

111148131

LLV:

125108462

MPUF:

101670990(TCF7L1)

MNP:	132021404(TCF7L1)

MLK:	131840380(TCF7L1)

NVS:	122915045(TCF7L1)

MMAQ:

308349917(TCF7L1)

ORO:	101382778(TCF7L1)

EJU:	114223462(TCF7L1)

ZCA:	113938298(TCF7L1)

MLX:	118007920(TCF7L1)

MANO:

123851118(TCF7L1)

NSU:	110587588(TCF7L1)

LWW:	102731685(TCF7L1)

FCA:	101089850(TCF7L1)

PYU:	121019121(TCF7L1)

PCOO:

112869689(TCF7L1)

PBG:	122497097(TCF7L1)

PVIV:

125162247(TCF7L1)

LRUF:

124503502

LGF:	123581039(TCF7L1)

AJU:

106978197

PTG:	102958078(TCF7L1)

PPAD:

109263707(TCF7L1)

PUC:

125937396

PLEZ:

122216264(TCF7L1)

HHV:	120220478(TCF7L1)

CCRU:

144221441(TCF7L1)

BTA:	515303(TCF7L1)

BOM:	102281039(TCF7L1)

BIU:	109565564(TCF7L1)

BJV:	133257157(TCF7L1)

BBUB:

102410081(TCF7L1)

BKE:	129623194(TCF7L1)

BBIS:

105004594(TCF7L1)

CHX:	102187776(TCF7L1)

OAS:	100913162(TCF7L1)

OCAN:

138436853(TCF7L1)

BTAX:

128056483(TCF7L1)

CSUM:

138082951(TCF7L1)

ODA:	120851515(TCF7L1)

CCAD:

122441729(TCF7L1)

MREE:

136162844(TCF7L1)

OVR:	110134759(TCF7L1)

MBEZ:

129538967(TCF7L1)

SSC:	100523899(TCF7L1)

CFR:	102516787(TCF7L1)

CBAI:

105072093(TCF7L1)

CDK:	105104146(TCF7L1)

VPC:	102525926(TCF7L1)

BACU:

103010166(TCF7L1)

BMUS:

118905868(TCF7L1)

LVE:	103069353(TCF7L1)

OOR:	101287223(TCF7L1)

LALB:

132531707(TCF7L1)

GMF:	115842518(TCF7L1)

DDP:	132435281(TCF7L1)

SCOO:

307196458(TCF7L1)

PCRS:

137206015(TCF7L1)

DLE:	111165393(TCF7L1)

PCAD:

102974053(TCF7L1)

PSIU:

116764402(TCF7L1)

PPHC:

136133849(TCF7L1)

NASI:

112399043(TCF7L1)

HAMP:

307064048(TCF7L1)

ECB:	100067427(TCF7L1)

EPZ:	103548276(TCF7L1)

EAI:	106838609(TCF7L1)

MYB:	102240393(TCF7L1)

MYD:	102768915(TCF7L1)

MMYO:

118668800(TCF7L1)

MLF:	102417756(TCF7L1)

MDT:	132213149(TCF7L1)

MYUM:

139020046(TCF7L1)

PKL:	118717604(TCF7L1)

EFUS:

103299070(TCF7L1)

POTS:

308255567(TCF7L1)

MNA:	107528616(TCF7L1)

DRO:	112302951(TCF7L1)

SHON:

118982463(TCF7L1) 118989528

AJM:	119059869(TCF7L1)

PDIC:

114499663(TCF7L1)

PHAS:

123811980(TCF7L1)

MMF:	118630569(TCF7L1)

PPAM:

129073949(TCF7L1)

HAI:	109371340(TCF7L1)

RFQ:	117033407(TCF7L1)

RHII:

308505601(TCF7L1)

PALE:

102886093(TCF7L1)

PGIG:

120594603(TCF7L1)

PVP:	105298541(TCF7L1)

RAY:	107506285(TCF7L1)

MJV:	108405898(TCF7L1)

TOD:	119259123(TCF7L1)

SARA:

101550691(TCF7L1)

SFUM:

130026040(TCF7L1)

SETR:

126024487(TCF7L1)

TMU:

101341696

ETF:	101655177(TCF7L1)

DNM:	101417902(TCF7L1)

MDO:	100030368(TCF7L1)

GAS:	123233138(TCF7L1)

SHR:	100922609(TCF7L1)

AFZ:

127547432

PCW:	110196343(TCF7L1)

TVP:	118844387(TCF7L1)

PBRV:

138144487(TCF7L1)

MLAO:

141495193(TCF7L1)

OAA:	114817948(TCF7L1)

TACU:

119939217(TCF7L1)

GGA:	395230(TCF7L1)

PCOC:

116231327(TCF7L1)

MGP:	104917108(TCF7L1)

CJO:	107323707(TCF7L1)

TPAI:

128090167(TCF7L1)

LMUT:

125685234(TCF7L1)

NMEL:

110387133(TCF7L1)

APLA:

101801135(TCF7L1)

AACU:

137845284(TCF7L1)

OJA:	118177510(TCF7L1)

BCLA:

308453544(TCF7L1)

ACYG:

106048886(TCF7L1)

ABRC:

308182892(TCF7L1)

CATA:

118260930(TCF7L1)

AFUL:

116499387(TCF7L1)

TGU:	115498209(TCF7L1)

LSR:	110478270(TCF7L1)

VMC:	128820044(TCF7L1)

VCHA:

128800898(TCF7L1)

AIB:	137463353(TCF7L1)

PMOA:

120505008(TCF7L1)

OTC:	121346667(TCF7L1)

PRUF:

121359809(TCF7L1)

ATRC:

139585207(TCF7L1)

MATE:

118695346(TCF7L1)

MAEN:

136567585(TCF7L1)

GFR:	102039905(TCF7L1)

FAB:	101817952(TCF7L1)

OMA:	130261854(TCF7L1)

PHI:	102105833(TCF7L1)

PMAJ:

107213891(TCF7L1)

CCAE:

111938914(TCF7L1)

CCW:	104683181(TCF7L1)

CBRC:

103620244(TCF7L1)

ACOE:

138121712(TCF7L1)

ETL:	114070472(TCF7L1)

ZLE:	135456937(TCF7L1)

SVG:	106862411(TCF7L1)

MMEA:

130586305(TCF7L1)

HRT:	120764102(TCF7L1)

SATI:

136372618(TCF7L1)

CCIC:

134054639(TCF7L1)

SHAB:

115618453(TCF7L1)

POCC:

134171772(TCF7L1)

FPG:	101922879(TCF7L1)

FCH:	102051021(TCF7L1)

FRS:	119140348(TCF7L1)

CCRI:

104165649

ANOC:

141971189(TCF7L1)

SURA:

141935637(TCF7L1)

TALA:

104362330(TCF7L1)

ACHC:

115349900(TCF7L1)

HLE:	104828923(TCF7L1)

AGEN:

126051625

HHAR:

128149931(TCF7L1)

BBUT:

142038355(TCF7L1)

GCL:

127025235

NNI:	104022615(TCF7L1)

PARX:

142068181(TCF7L1)

AFOR:

103904221(TCF7L1)

CBOR:

142093492(TCF7L1)

CBOY:

140643800(TCF7L1)

MAME:

142420155(TCF7L1)

CLV:	102084814(TCF7L1)

CNIC:

135998325(TCF7L1)

NMAY:

308050333(TCF7L1)

CUCA:

104067006(TCF7L1)

PCUR:

138731516(TCF7L1)

GAME:

129196765(TCF7L1)

CPEA:

104392687(TCF7L1)

CVF:	104285063(TCF7L1)

RTD:	128919648(TCF7L1)

CRID:

134526533(TCF7L1)

LMIC:

141733297(TCF7L1)

NARQ:

141475783(TCF7L1)

AAM:

106497459

AROW:

112971101(TCF7L1)

DNE:

112994866

ASN:	102382172(TCF7L1)

AMJ:	102559656(TCF7L1)

CPOO:

109324635(TCF7L1)

GGN:	109286704(TCF7L1)

PSS:	102456229(TCF7L1)

CIZ:	142004159(TCF7L1)

CMY:	102947844(TCF7L1)

CCAY:

125626470(TCF7L1)

LKP:	140903546(TCF7L1)

NDS:	141978302(TCF7L1)

DCC:	119848739(TCF7L1)

CPIC:

101943923(TCF7L1)

TST:	117872874(TCF7L1)

EOB:	135875073(TCF7L1)

CABI:

116820735(TCF7L1)

MRV:	120397584(TCF7L1)

EMQ:	137151554(TCF7L1)

ACS:	100553130(tcf7l1)

ASAO:

132782760(TCF7L1)

PVT:	110084320(TCF7L1)

SUND:

121934613(TCF7L1)

PBI:	103066724(TCF7L1)

PMUR:

107286235(TCF7L1)

CTIG:

120313945(TCF7L1)

TSR:	106539368(TCF7L1)

PGUT:

117677059(TCF7L1)

PCAE:

139323020(TCF7L1)

APRI:

131203795(TCF7L1)

PTEX:

113447733(TCF7L1)

NSS:	113414485(TCF7L1)

VKO:	123027052(TCF7L1)

PMUA:

114585748(TCF7L1)

PRAF:

128402557(TCF7L1)

ZVI:	118097303(TCF7L1)

HCG:	128333530(TCF7L1)

GJA:	107117396(TCF7L1)

STOW:

125441754(TCF7L1)

EMC:	129342060(TCF7L1)

XLA:	394281(tcf7l1.S) 397863(tcf7l1.L)

XTR:	448107(tcf7l1)

NPR:

108792469

RTEM:

120933071(TCF7L1)

ACAT:

141133073(TCF7L1)

PADS:

140324792(TCF7L1)

BBUF:

120986167(TCF7L1)

BGAR:

122929474(TCF7L1)

DTC:	141100273(TCF7L1)

HSQ:	130366820(TCF7L1)

PCOB:

134936706(TCF7L1)

PWL:	138265987(TCF7L1)

MUO:	115469279(TCF7L1)

GSH:	117362505(TCF7L1)

DRE:	30523(tcf7l1a) 30556(tcf7l1b)

DAES:

130234324(tcf7l1b) 130235914(tcf7l1a)

SRX:	107721095 107746220 107747791 107758653

SANH:

107658535 107689229 107698102

SGH:	107556226 107558109 107563849 107602061

CCAR:

109061477(tcf7l1a) 109065562 109069847 109094448

CAUA:

113054570 113070993 113107300 113110247

CGIB:

127963698 127965925 127966705 128018304 128020720

PTET:

122350851(tcf7l1b) 122353201(tcf7l1a) 122358150

LROH:

127169871(tcf7l1b) 127172457(tcf7l1a)

GRF:	141298764(tcf7l1a)

OMC:	131545540(tcf7l1b) 131548395(tcf7l1a)

PPRM:

120474207(tcf7l1a) 120481307(tcf7l1b)

RKG:	130078054(tcf7l1a) 130082133(tcf7l1b)

SCEP:

307152570(tcf7l1a) 307173272(tcf7l1b)

MAMB:

125262345(tcf7l1a) 125280430(tcf7l1b)

CIDE:

127517104 127521501

CERY:

137027367(tcf7l1b) 137029462(tcf7l1a)

MASI:

127415459 127423965 127432983 127433839

TROS:

130546223(tcf7l1a) 130568298(tcf7l1b)

TDW:	130407032(tcf7l1b) 130411805(tcf7l1a)

MANU:

129414006(tcf7l1b) 129446566(tcf7l1a)

PDAB:

135729780(tcf7l1b) 135744001(tcf7l1a)

IPU:	108265410(tcf7l1b)

IFU:	128607348(tcf7l1b)

PHYP:

113546045

SMEO:

124399623(tcf7l1b)

TFD:	113645099(tcf7l1b)

TVC:	132853353(tcf7l1b)

CGAR:

128529893(tcf7l1b)

NGRA:

132892804(tcf7l1b)

TRN:	134318428(tcf7l1b)

AMEX:

103022374(tcf7l1b)

CMAO:

118813135(tcf7l1b) 118824685(tcf7l1a)

EEE:	113586207 113589257

CHAR:

105902771(tcf7l1b) 105912913(tcf7l1a)

SPIL:

134100835(tcf7l1a)

ASAD:

121680482(tcf7l1a) 121714764

TRU:	101063163(tcf7l1b) 101074632 115250984 115250985

TFS:	130516798(tcf7l1a) 130525287(tcf7l1b)

TNG:	GSTEN00011518G001 GSTEN00025415G001

NCC:	104946533(tcf7l1)

TBEN:

117482633 117496881(tcf7l1b)

CGOB:

115013514 115016853

PGEO:

117452970(tcf7l1b)

GACU:

117556347 117561075(tcf7l1b)

EMAC:

134868341 134874085(tcf7l1b)

ELY:	117253031(tcf7l1b) 117254049 117269726

EFO:	125890368(tcf7l1b) 125905690

PLEP:

121938910 121944425(tcf7l1b)

SLUC:

116041786 116053887(tcf7l1b)

SVIT:

144518750(tcf7l1b)

ECRA:

117944255 117959748

ESP:	116685754 116686075

PFLV:

114555040 114571186

PFLT:

120560332(tcf7l1b)

GAT:	120831035 120831649

PPUG:

119224565 119226883

AFB:	129100781(tcf7l1b) 129102375

CLUM:

117736417(tcf7l1b) 117740101

PSWI:

130197066(tcf7l1b) 130205718(tcf7l1a)

CANA:

137783567(tcf7l1a) 137805430(tcf7l1b)

TBU:	306740417(tcf7l1b)

CVE:	137867218(tcf7l1b) 137868541

AMIR:

142964180(tcf7l1b)

MSAM:

119896780 119914157 119914244

SCHU:

122865509 122876664(tcf7l1b)

EARM:

139284782(tcf7l1b) 139301025

CUD:	121510420 121524704

SPUL:

138601854 138610082(tcf7l1b)

LMIX:

132967192 132974034(tcf7l1b)

HTC:	141790876(tcf7l1b) 141805935

ALAT:

119019317(tcf7l1b) 119030554(tcf7l1a)

ASTR:

137592062(tcf7l1b) 137608673

PKLU:

139204526 139218822(tcf7l1a)

LCO:	104935330 104937897

AMMM:

307258694(tcf7l1b)

MZE:	101466461 101481605(tcf7l1b)

ONL:	100692408 100693117 100698220 100705177 102075719

OAU:	116321645 116323960(tcf7l1b) 116333212 120434776 120435026 120437054 120441818 120442056

OLA:	100820729(tcf7l1) 111948314

OML:	112148818(tcf7l1b) 112162929

CSAI:

133450325(tcf7l1b)

XMA:	102218641 102234111

XCO:	114150160 114154484

XHE:	116725078 116729763

PRET:

103470543(tcf7l1b) 103473136 103473327

PFOR:

103146213 103153233

PLAI:

106962954 106963692

PMEI:

106915824 106931867

GAF:	122828060(tcf7l1b) 122847224

PPRL:

129371953(tcf7l1b) 129379828

CVG:	107082304 107096394

CTUL:

119783953(tcf7l1b)

GMU:	124872815 124878390(tcf7l1b)

NFU:	107393717(tcf7l1) 107395259

KMR:	108236527(tcf7l1b) 108242566

ALIM:

106513792 106520143(tcf7l1)

NWH:	119414015 119424771

LTU:	140276656 140310087(tcf7l1b)

MCEP:

124996986 125012430(tcf7l1b)

AOCE:

111579349 111586711(tcf7l1b)

EJA:	138208845 138215825(tcf7l1b)

BFRE:

138621610(tcf7l1b) 138622291

LCF:	108878678(tcf7l1b) 108895925 108900803

CSEM:

103389353 103397252 103397348

POV:	109633880 109642773

SSEN:

122758446 122769535(tcf7l1b)

SSOE:

131446597 131463937(tcf7l1b)

HHIP:

117767600(tcf7l1b) 117771319(tcf7l1a)

HSP:	118114860(tcf7l1b) 118126041(tcf7l1a)

PPLT:

128425127(tcf7l1a) 128437962(tcf7l1b)

SMAU:

118284957 118314250(tcf7l1b)

SDU:	111224272 111226848 111226906

SLAL:

111645025 111664452

XGL:	120805718(tcf7l1b) 120806258

HCQ:	109507825 109525057 109527933

SSCV:

125993929(tcf7l1b)

SBIA:

133491088 133499396(tcf7l1b)

PEE:	133399727(tcf7l1b) 133413646

PTAO:

133475547(tcf7l1b) 133489903

BPEC:

110161575 110169813

ENY:	140346496(tcf7l1b) 140367626(tcf7l1a)

MALB:

109954978

BSPL:

114861532(tcf7l1b) 114866425

SJO:	128364144(tcf7l1b) 128380140

SSCO:

133978574(tcf7l1b) 133995526(tcf7l1a)

TTY:	137170657 137194320(tcf7l1b)

GMH:	115541913 115553540

SASA:

106563056 106567996 106580381 106585616

STRU:

115159747 115164508 115200136 115203917(tcf7l1a)

OTW:	112220252 112230828(tcf7l1a) 112248495 112262905

OMY:	110509652(tcf7l1a) 110523432 110526333 110536043

OGO:	124006940(tcf7l1a) 124034311 124036311 124049101

ONE:	115101019 115111609 115120981 115131934

OKI:	109868277 109873955 109879721 109895902

OKE:	118374384 118385451(tcf7l1a) 118387418 118394059

OMM:	135514094 135518109 135541733 135544617(tcf7l1a)

OCLA:

139388020 139389696 139408539 139410921

SALP:

111957791 111961773 111974657

SNH:	120020954 120021019 120026317 120063242

SFON:

129818231 129826327 129853582 129863791

CCLU:

121530904 121541546 121582658 121584851

ELS:	105014239 105015187

OEP:	134012146(tcf7l1b) 134038629(tcf7l1a)

SFM:	108923598 108929514(tcf7l1)

PKI:	111837756 111857498(tcf7l1)

AANG:

118206870(tcf7l1b)

AROT:

135240094 135261279(tcf7l1b)

CCOG:

133140725(tcf7l1b) 133141989

LOC:	102692120(tcf7l1)

PSPA:

121302353 121303125

ARUT:

117397962 117962397

PSEX:

120538925(tcf7l1a)

LCM:	102364488(TCF7L1)

RTP:

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

Reference

PMID:17143293

Authors

Arce L, Yokoyama NN, Waterman ML

Title

Diversity of LEF/TCF action in development and disease.

Journal

Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

Reference

PMID:1741298

Authors

Castrop J, van Norren K, Clevers H

Title

A gene family of HMG-box transcription factors with homology to TCF-1.

Journal

Nucleic Acids Res 20:611 (1992)
DOI:10.1093/nar/20.3.611

Sequence

[hsa:83439]

All links

Gene (502)   
   MGENES (231)   
   RefGene (262)   
   OC (9)   
All databases (502)   

Download RDF

ORTHOLOGY: K04491

Entry

K04491                      KO

Symbol

TCF7L2

Name

transcription factor 7-like 2

Pathway

map04310

Wnt signaling pathway

map04390

Hippo signaling pathway

map04519

Cadherin signaling

map04520

Adherens junction

map04916

Melanogenesis

map04934

Cushing syndrome

map04936

Alcoholic liver disease

map05132

Salmonella infection

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05200

Pathways in cancer

map05210

Colorectal cancer

map05213

Endometrial cancer

map05215

Prostate cancer

map05216

Thyroid cancer

map05217

Basal cell carcinoma

map05221

Acute myeloid leukemia

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05412

Arrhythmogenic right ventricular cardiomyopathy

Disease

H00409

Type 2 diabetes mellitus

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04491  TCF7L2; transcription factor 7-like 2
   04390 Hippo signaling pathway
    K04491  TCF7L2; transcription factor 7-like 2
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    K04491  TCF7L2; transcription factor 7-like 2
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04491  TCF7L2; transcription factor 7-like 2
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04491  TCF7L2; transcription factor 7-like 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04491  TCF7L2; transcription factor 7-like 2
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05225 Hepatocellular carcinoma
    K04491  TCF7L2; transcription factor 7-like 2
   05226 Gastric cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05216 Thyroid cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05221 Acute myeloid leukemia
    K04491  TCF7L2; transcription factor 7-like 2
   05217 Basal cell carcinoma
    K04491  TCF7L2; transcription factor 7-like 2
   05215 Prostate cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05213 Endometrial cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05224 Breast cancer
    K04491  TCF7L2; transcription factor 7-like 2
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04491  TCF7L2; transcription factor 7-like 2
   05165 Human papillomavirus infection
    K04491  TCF7L2; transcription factor 7-like 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04491  TCF7L2; transcription factor 7-like 2
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04491  TCF7L2; transcription factor 7-like 2
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04491  TCF7L2; transcription factor 7-like 2
   04934 Cushing syndrome
    K04491  TCF7L2; transcription factor 7-like 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04491  TCF7L2; transcription factor 7-like 2
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04491  TCF7L2; transcription factor 7-like 2

Genes

HSA:	6934(TCF7L2)

PTR:	450743(TCF7L2)

PPS:	100978424(TCF7L2)

GGO:	109025238(TCF7L2)

PON:	100434811(TCF7L2)

PPYG:

129045299(TCF7L2)

NLE:	100605701(TCF7L2)

HMH:	116483446(TCF7L2)

SSYN:

129466010(TCF7L2)

MCC:	701759(TCF7L2)

MCF:	102116470(TCF7L2)

MTHB:

126962827

MNI:	105467983(TCF7L2)

CSAB:

103216817(TCF7L2)

CATY:

105577906(TCF7L2)

PANU:

101026705(TCF7L2)

TGE:	112631247(TCF7L2)

MLEU:

105530146(TCF7L2)

RRO:	104664436(TCF7L2)

RBB:	108542456(TCF7L2)

TFN:	117066750(TCF7L2)

PTEH:

111538904(TCF7L2)

CANG:

105501828(TCF7L2)

CJC:	100406757(TCF7L2)

SBQ:	101037011(TCF7L2)

CIMI:

108311134

ANAN:

105714167(TCF7L2)

CSYR:

103256089(TCF7L2)

MMUR:

105875160(TCF7L2)

LCAT:

123649863(TCF7L2)

ERUF:

138376473(TCF7L2)

PCOQ:

105826013(TCF7L2)

OGA:	100943434(TCF7L2)

MMU:	21416(Tcf7l2)

MCAL:

110285273(Tcf7l2)

MPAH:

110313411(Tcf7l2)

RNO:	679869(Tcf7l2)

MCOC:

116104020(Tcf7l2)

ANU:	117718257(Tcf7l2)

ASYL:

127685650(Tcf7l2)

MUN:	110545126(Tcf7l2)

CGE:	100758400(Tcf7l2)

MAUA:

101831174(Tcf7l2)

PROB:

127233545(Tcf7l2)

PLEU:

114697060(Tcf7l2)

PMAV:

102926102(Tcf7l2)

MORG:

121453859(Tcf7l2)

MFOT:

126505923

AAMP:

119806595(Tcf7l2)

CNL:	130879157(Tcf7l2)

NGI:	103731749(Tcf7l2)

HGL:	101710380(Tcf7l2)

CPOC:

100715721(Tcf7l2)

CCAN:

109688561(Tcf7l2)

DORD:

105986725(Tcf7l2)

DSP:	122115716(Tcf7l2)

DMER:

138803881(Tcf7l2)

PLOP:

125345434 125345456 125346046(Tcf7l2)

NCAR:

124984748

SVUL:

306659777(TCF7L2)

MMMA:

107149900(Tcf7l2)

ITI:	101965611(Tcf7l2)

SCIL:

308633906(TCF7L2)

MAVE:

308262126(TCF7L2)

OCU:

100358378

OPI:	101521047(TCF7L2)

OCZ:	121164137(TCF7L2) 121166356

TUP:	102472810(TCF7L2)

GVR:	103589124(TCF7L2)

CFA:	486894(TCF7L2)

CLUD:

112672346(TCF7L2)

VVP:	112916157(TCF7L2)

VLG:	121485032(TCF7L2)

NPO:	129493862(TCF7L2)

AML:	100467719(TCF7L2)

UMR:	103657263(TCF7L2)

UAH:	113251942(TCF7L2)

UAR:	123795969(TCF7L2)

ELK:

111145217

LLV:

125084325

MPUF:

101676452(TCF7L2)

MNP:	132016786(TCF7L2)

MLK:	131830678(TCF7L2)

NVS:	122901120(TCF7L2)

MMAQ:

308354863(TCF7L2)

ORO:	101385846(TCF7L2)

EJU:	114202903 114202904

ZCA:	113923025(TCF7L2)

MLX:	118026323(TCF7L2)

MANO:

123846859(TCF7L2)

NSU:	110589494(TCF7L2)

LWW:	102745990(TCF7L2)

FCA:	101095618(TCF7L2)

PYU:	121037238(TCF7L2)

PCOO:

112854283(TCF7L2)

PBG:	122493255(TCF7L2)

PVIV:

125147670(TCF7L2)

LRUF:

124507146

LGF:	123577083(TCF7L2)

AJU:

106974119

PTG:	102961321(TCF7L2)

PPAD:

109272915(TCF7L2)

PUC:

125932981

PLEZ:

122202378(TCF7L2)

HHV:	120235337(TCF7L2)

CCRU:

144244218(TCF7L2)

BTA:	540481(TCF7L2)

BOM:	102272230(TCF7L2)

BIU:	109553057(TCF7L2)

BJV:	133239418(TCF7L2)

BBUB:

102393101(TCF7L2)

BKE:	129636647(TCF7L2)

BBIS:

105002610(TCF7L2)

CHX:	102180102(TCF7L2)

OAS:	101118068(TCF7L2)

OCAN:

138427559(TCF7L2)

BTAX:

128067999(TCF7L2)

CSUM:

138070171(TCF7L2)

ODA:	120873902(TCF7L2)

CCAD:

122445909(TCF7L2)

MREE:

136160134(TCF7L2)

OVR:	110128553(TCF7L2)

MBEZ:

129555340(TCF7L2)

SSC:	100153922(TCF7L2)

CFR:	102510763(TCF7L2)

CBAI:

105080737(TCF7L2)

CDK:	105091689(TCF7L2)

VPC:	102525508(TCF7L2)

BACU:

103010923(TCF7L2)

BMUS:

118882500(TCF7L2) 118888134

LVE:	103068781(TCF7L2)

OOR:	101288107(TCF7L2)

LALB:

132506792(TCF7L2)

GMF:	115844969(TCF7L2)

DDP:	132439596(TCF7L2)

SCOO:

307174914(TCF7L2)

PCRS:

137208759(TCF7L2)

DLE:	111172300(TCF7L2)

PCAD:

102987858(TCF7L2)

PSIU:

116741601(TCF7L2)

PPHC:

136135944(TCF7L2)

NASI:

112406953(TCF7L2)

HAMP:

307056133(TCF7L2)

ECB:	100059146(TCF7L2)

EPZ:	103564289(TCF7L2)

EAI:	106848101(TCF7L2)

MYB:	102245737(TCF7L2)

MYD:	102767014(TCF7L2)

MMYO:

118669739(TCF7L2)

MLF:	102428683(TCF7L2)

MDT:	132214342(TCF7L2)

MYUM:

139021727(TCF7L2)

PKL:	118719486(TCF7L2)

EFUS:

103288569(TCF7L2)

POTS:

308234775(TCF7L2)

MNA:	107536455(TCF7L2)

DRO:	112300313(TCF7L2)

SHON:

118999410(TCF7L2)

AJM:	119040094(TCF7L2)

PDIC:

114496676(TCF7L2)

PHAS:

123828741(TCF7L2)

MMF:	118632022(TCF7L2)

PPAM:

129077183(TCF7L2)

HAI:	109384898(TCF7L2)

RFQ:	117035906(TCF7L2)

RHII:

308507862(TCF7L2)

PALE:

102880370(TCF7L2)

PGIG:

120609085(TCF7L2)

PVP:	105291480(TCF7L2)

RAY:	107511705(TCF7L2)

MJV:	108408173(TCF7L2)

TOD:	119234547(TCF7L2)

SARA:

101546297(TCF7L2)

SFUM:

130029493(TCF7L2)

SETR:

125994905(TCF7L2)

LAV:	100656106(TCF7L2)

TMU:

101345532

ETF:	101657493(TCF7L2)

DNM:	101433286(TCF7L2)

MDO:	100021451(TCF7L2)

GAS:	123238173(TCF7L2)

SHR:	100922675(TCF7L2)

AFZ:

127551589

PCW:	110209517(TCF7L2)

TVP:	118828293(TCF7L2)

PBRV:

138169488(TCF7L2)

MLAO:

141521273(TCF7L2)

OAA:	100080633(TCF7L2)

TACU:

119937953(TCF7L2)

GGA:	395508(TCF7L2)

PCOC:

116231615(TCF7L2)

MGP:

100545943

CJO:	107316122(TCF7L2)

TPAI:

128077851(TCF7L2)

LMUT:

125693546(TCF7L2)

NMEL:

110399432(TCF7L2)

APLA:

101790790(TCF7L2)

AACU:

137859491(TCF7L2)

OJA:	118168918(TCF7L2)

BCLA:

308445961(TCF7L2)

ACYG:

106031894(TCF7L2)

ABRC:

308197563(TCF7L2)

CATA:

118248729(TCF7L2)

AFUL:

116491447(TCF7L2)

TGU:	100229459(TCF7L2)

LSR:	110468252(TCF7L2)

VMC:	128810770(TCF7L2)

VCHA:

128791451(TCF7L2)

AIB:	137478312(TCF7L2)

SCAN:

103814128(TCF7L2)

PMOA:

120501961(TCF7L2)

OTC:	121341849(TCF7L2)

PRUF:

121350212(TCF7L2)

ATRC:

139599079(TCF7L2)

MATE:

118688415(TCF7L2)

MAEN:

136559174(TCF7L2)

GFR:	102035103(TCF7L2)

FAB:	101808150(TCF7L2)

OMA:	130254705(TCF7L2)

PHI:	102110960(TCF7L2)

PMAJ:

107206579(TCF7L2)

CCAE:

111930957(TCF7L2)

CCW:	104695213(TCF7L2)

CBRC:

103616275(TCF7L2)

ACOE:

138112637(TCF7L2)

ETL:	114057387(TCF7L2)

ZAB:	102075283(TCF7L2)

ZLE:	135449944(TCF7L2)

ACHL:

103800973(TCF7L2)

SVG:	106850869(TCF7L2)

MMEA:

130581829(TCF7L2)

HRT:	120755667(TCF7L2)

SATI:

136364028(TCF7L2)

CFAI:

136293842(TCF7L2)

CCIC:

134046114(TCF7L2)

NNT:	104411918(TCF7L2)

SHAB:

115607965(TCF7L2)

POCC:

134158181(TCF7L2)

FPG:	101911463(TCF7L2)

FCH:	102053252(TCF7L2)

FRS:	119153346(TCF7L2)

CCRI:

104158774

ACUN:

113481635(TCF7L2)

ANOC:

141961140(TCF7L2)

SURA:

141946091(TCF7L2)

TALA:

104368758(TCF7L2)

ACHC:

115348196(TCF7L2)

HALD:

104324218(TCF7L2)

HLE:	104830209(TCF7L2)

AGEN:

126043148

HHAR:

128146735(TCF7L2)

BBUT:

142030357(TCF7L2)

GCL:

127017519

CSTI:

104553138(TCF7L2)

LDI:	104346347(TCF7L2)

MNB:

103774896

DPUB:

104307193(TCF7L2)

PPUS:

135175920(TCF7L2)

IIN:	128967954(TCF7L2)

EGZ:	104130428(TCF7L2)

NNI:	104022375(TCF7L2)

PCRI:

104033644(TCF7L2)

PCAO:

104051703(TCF7L2)

PARX:

142063889(TCF7L2)

PADL:

103918670(TCF7L2)

AFOR:

103897740(TCF7L2)

FGA:	104083847(TCF7L2)

CBOR:

142084403(TCF7L2)

GSTE:

104263863

CBOY:

140655657(TCF7L2)

MAME:

142411145(TCF7L2)

CLV:	102092542(TCF7L2)

CNIC:

135990695(TCF7L2)

NMAY:

308042529(TCF7L2)

MUI:	104548075(TCF7L2)

PGUU:

104464988

PLET:

104620802(TCF7L2)

EHS:

104510766

CMAC:

104478637(TCF7L2)

CUCA:

104067818(TCF7L2)

PCUR:

138723861(TCF7L2)

TEO:	104384501(TCF7L2)

BREG:

104643624(TCF7L2)

GAME:

129208724(TCF7L2)

OHA:	104329504(TCF7L2)

ACAR:

104527872(TCF7L2)

CEUR:

306719771(TCF7L2)

CPEA:

104397916(TCF7L2)

CVF:	104283459(TCF7L2)

RTD:	128911762(TCF7L2)

CRID:

134517067(TCF7L2)

LMIC:

141745243(TCF7L2)

NARQ:

141472163(TCF7L2)

AAM:	106483723(TCF7L2)

AROW:

112967920(TCF7L2)

NPD:	112957063(TCF7L2)

TGT:

104570256

DNE:	112993664(TCF7L2)

SCAM:

104140131

ASN:	102373887(TCF7L2)

AMJ:	102558653(TCF7L2)

CPOO:

109324083(TCF7L2)

GGN:	109287622(TCF7L2)

PSS:	102459521(TCF7L2)

CIZ:	142015570(TCF7L2)

CMY:	102935138(TCF7L2)

CCAY:

125639965(TCF7L2)

LKP:	140915029(TCF7L2)

NDS:	141991160(TCF7L2)

DCC:	119858498(TCF7L2)

CPIC:

101938831(TCF7L2)

TST:	117879792(TCF7L2)

EOB:	135881302(TCF7L2)

CABI:

116832677(TCF7L2)

MRV:	120409598(TCF7L2)

EMQ:	137146052(TCF7L2)

ACS:	100561311(tcf7l2) 100563899

ASAO:

132770959(TCF7L2)

PVT:	110071969(TCF7L2)

SUND:

121924798(TCF7L2)

PBI:	103067231(TCF7L2)

PMUR:

107286251(TCF7L2)

CTIG:

120312245(TCF7L2)

TSR:	106550184(TCF7L2)

PGUT:

117678715(TCF7L2)

PCAE:

139318574(TCF7L2)

APRI:

131200547(TCF7L2)

PTEX:

113439111(TCF7L2)

NSS:	113413891(TCF7L2)

VKO:	123027730(TCF7L2)

PMUA:

114597477(TCF7L2)

PRAF:

128414229(TCF7L2)

ZVI:	118093455(TCF7L2)

HCG:	128350353(TCF7L2)

GJA:	107121002(TCF7L2)

STOW:

125437427(TCF7L2)

EMC:	129331736(TCF7L2)

XLA:	108697306 399164(tcf7l2.L)

XTR:	100101719(tcf7l2)

NPR:	108793512(TCF7L2)

RTEM:

120946834(TCF7L2)

ACAT:

141105771(TCF7L2)

PADS:

140339219(TCF7L2)

BBUF:

121005422(TCF7L2)

BGAR:

122939052(TCF7L2)

DTC:	141074876(TCF7L2)

HSQ:	130282536(TCF7L2)

PCOB:

135056879(TCF7L2)

PWL:	138300245(TCF7L2)

MUO:	115469932(TCF7L2)

GSH:	117358752(TCF7L2)

DRE:	30510(tcf7l2)

DAES:

130238515(tcf7l2)

SRX:	107750316 107755529

SANH:

107684123 107702422

SGH:	107566231 107581563

CCAR:

109056663 109100220(tcf7l2)

CAUA:

113069495 113111589

CGIB:

127969142 128025372

PTET:

122351900 122355452(tcf7l2)

LROH:

127174150(tcf7l2)

GRF:	141298365(tcf7l2)

OMC:	131550611(tcf7l2)

PPRM:

120474612(tcf7l2)

RKG:	130102768(tcf7l2)

SCEP:

307147386(tcf7l2)

MAMB:

125255599(tcf7l2)

CIDE:

127523576

CERY:

137007969(tcf7l2)

MASI:

127422938 127426883

TROS:

130568894(tcf7l2)

TDW:	130438678(tcf7l2)

MANU:

129420463(tcf7l2)

PDAB:

135744617(tcf7l2)

IPU:

108274114

IFU:	128617569(tcf7l2)

PHYP:

113527302(tcf7l2)

SMEO:

124388632(tcf7l2)

TFD:	113638911(tcf7l2)

TVC:	132837872(tcf7l2)

CGAR:

128541072(tcf7l2)

NGRA:

132898397(tcf7l2)

TRN:	134321330(tcf7l2)

AMEX:

103031257(tcf7l2)

CMAO:

118809394(tcf7l2)

EEE:

113577640

CHAR:

105912592(tcf7l2)

SPIL:

134061967

ASAD:

121696832(tcf7l2)

TRU:	101067664(tcf7l2) 115250775

TFS:	130525331(tcf7l2)

TNG:	GSTEN00019527G001

NCC:	104943463(tcf7l2)

TBEN:

117473593(tcf7l2)

CGOB:

115024930(tcf7l2)

PGEO:

117465006 117465007

GACU:

117543165(tcf7l2)

EMAC:

134870639(tcf7l2)

ELY:	117247028(tcf7l2)

EFO:	125880423(tcf7l2)

PLEP:

121958519(tcf7l2)

SLUC:

116061043(tcf7l2)

SVIT:

144535822(tcf7l2)

ECRA:

117936627(tcf7l2)

ESP:	116671026(tcf7l2)

PFLV:

114547666(tcf7l2)

PFLT:

120551037(tcf7l2)

GAT:	120819326(tcf7l2)

PPUG:

119213174(tcf7l2)

AFB:	129091849(tcf7l2)

CLUM:

117748491(tcf7l2)

PSWI:

130203272(tcf7l2)

CANA:

137789858(tcf7l2)

TBU:	306753784(tcf7l2)

CVE:	137886679(tcf7l2)

AMIR:

142951919(tcf7l2)

MSAM:

119911965 119915700(tcf7l2)

SCHU:

122867452(tcf7l2)

EARM:

139303399(tcf7l2)

CUD:	121528169(tcf7l2)

SPUL:

138593519(tcf7l2)

LMIX:

132955129(tcf7l2)

HTC:	141785597(tcf7l2)

ALAT:

119009368(tcf7l2)

ASTR:

137588113(tcf7l2)

PKLU:

139219413(tcf7l2)

LCO:	104932553(tcf7l2)

AMMM:

307267332(tcf7l2)

MZE:	101472434 101473558(tcf7l2)

ONL:	100697366 100704057(tcf7l2) 109194146

OAU:	116327522(tcf7l2) 116335916 120434774

OLA:	101169492(tcf7l2)

OML:	112154020(tcf7l2)

CSAI:

133418942(tcf7l2)

XMA:	102216716(tcf7l2)

XCO:	114151877(tcf7l2)

XHE:	116726851(tcf7l2)

PRET:

103481429(tcf7l2)

PFOR:

103142270(tcf7l2)

PLAI:

106949585

PMEI:

106920911(tcf7l2)

GAF:	122822874(tcf7l2)

PPRL:

129367839(tcf7l2)

CVG:	107090000(tcf7l2)

CTUL:

119774953(tcf7l2)

GMU:	124874826(tcf7l2)

NFU:	107387573(tcf7l2)

KMR:	108248252(tcf7l2)

ALIM:

106534544(tcf7l2)

NWH:	119424011(tcf7l2)

LTU:	140278926(tcf7l2)

MCEP:

125022588(tcf7l2)

AOCE:

111579048(tcf7l2)

EJA:	138201905(tcf7l2)

BFRE:

138617094(tcf7l2)

LCF:

108901696

CSEM:

103381486(tcf7l2) 103385014

POV:	109627028(tcf7l2)

SSEN:

122759724(tcf7l2)

SSOE:

131448193(tcf7l2)

HHIP:

117753439(tcf7l2)

HSP:	118100785(tcf7l2)

PPLT:

128426520(tcf7l2)

SMAU:

118287728(tcf7l2)

SDU:	111219725(tcf7l2)

SLAL:

111657117(tcf7l2)

XGL:	120794076(tcf7l2)

HCQ:	109513392(tcf7l2)

SSCV:

125991191(tcf7l2)

SBIA:

133495832(tcf7l2)

PEE:	133417553(tcf7l2)

PTAO:

133468900(tcf7l2)

BPEC:

110154410(tcf7l2)

ENY:	140368821(tcf7l2)

MALB:

109962891(tcf7l2)

BSPL:

114846309(tcf7l2)

SJO:	128381904(tcf7l2)

SSCO:

134003738(tcf7l2)

TTY:	137172306(tcf7l2)

GMH:	115531013(tcf7l2)

SASA:

106579026 106589326

STRU:

115158068 115201081

OTW:	112223237 112224184

OMY:	110491462 110499059

OGO:	124039973 124048226(tcf7l2)

ONE:	115106433 115143988

OKI:	109865440 109869968

OKE:	118357546 118367342

OMM:	135505062(tcf7l2) 135523901

OCLA:

139368037 139376504

SALP:

111967698 111978135

SNH:	120029841 120046309

SFON:

129829202 129838268

CCLU:

121549957 121586406

ELS:	105007703(tcf7l2)

OEP:	134030803(tcf7l2)

SFM:	108932732 108940446(tcf7l2)

PKI:	111858155(tcf7l2)

AANG:

118220560(tcf7l2)

AROT:

135247587(tcf7l2)

CCOG:

133114420(tcf7l2)

LOC:	102691677(tcf7l2)

PSPA:

121321701 121325528

ARUT:

117415317 117418190

PSEX:

120543224(tcf7l2)

LCM:	102346208(TCF7L2)

CMK:	103186546(tcf7l2)

RTP:	109926936(tcf7l2)

CPLA:

122561195(tcf7l2)

CPUN:

140463456(tcf7l2)

HOC:	132826295(tcf7l2)

SCAU:

119979259(tcf7l2)

CMAM:

144694389(tcf7l2)

LERI:

129704026(tcf7l2)

HAKA:

140715478(tcf7l2)

PMRN:

116940279 116950998

LRJ:	133350601 133354480

BFO:

118412533

BBEL:

109485396

CIN:	778773(tcf/lef)

SCLV:

120328830 120347390

SPU:	373203(Tcf/Lef)

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:	100303556(tcf7l)

PFLL:

139123280

DME:	Dmel_CG34403(pan)

DER:

6555877

DSI:	Dsimw501_GD17850(Dsim_pan)

DYA:	Dyak_GE14535

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI14114

DAZ:

108617901

DNV:	108657792 108657913

DHE:

111597895

DVI:	6636240(pan)

BOD:	106619378(pan)

TDA:

119684323

MDE:	101891022 131800416

SCAC:

106082602

LCQ:

111687000

CVJ:	135962856(pan)

CLON:

129606639 129607019 129608591

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ADAR:

ACOS:

AAG:	5565423 5565437

AALB:

109426030 115268047

ASUA:

134227230 134227257

CQU:	CpipJ_CPIJ005215 CpipJ_CPIJ013554 CpipJ_CPIJ013913

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

CFEL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208615

BANY:

112058326

MJU:

123877387

NIQ:

126777880

VCD:	124540396(pan)

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137925294(pan)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:	110372629(pan)

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

ECLR:

PXY:	105381194(pan)

PGW:

126377867

LGLY:

125237359

CSTB:

134751413

CFUM:

141438650(pan)

TCA:	641465(Pan)

TMOL:

138131970(pan)

DPA:

109535398

ESIM:

136414331(pan)

EFOR:

136346250(pan)

SOY:

115883697

RFG:	143198971(pan)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

135794115(pan)

PPYR:

OTU:

CCRN:

AME:

ALAB:

ADR:

BIM:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

TAME:

HST:

DQU:

CFO:

PMEC:

LHU:

PGC:

OBO:

PCF:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

API:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106686555(pan)

NLU:

111047051

LDA:	142321089(pan)

HVI:

124359738

MQU:	128983220 129005330

PHU:	Phum_PHUM222010

FOC:

TPAL:

ZNE:

CSEC:

BROR:

HAMR:

FCD:

DMK:

DPZ:

AFRA:

EAF:

LSM:	121117145 121130765

TCF:	131887804 131888978

PVM:	113823041(pan)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

SPRM:

ESN:

MNZ:

MRJ:	136833477(pan)

PORN:

139759194(pan)

OOT:

HAZT:

ISC:

DSV:

DALB:

135918206(pan)

RSAN:

119393871

RMP:	119161120(pan)

VJA:

111267083

GOE:

100905988

TUT:	107363428 107363430

DPTE:

113799178

CSCU:

111612922 111629408

CVS:	136970179 136981035

PTEP:

107449152 107450033

ABRU:

129962688 129976316

UDV:	129225971 129235227

SDM:	118183748 118189550

LPOL:

106461635

CEL:	CELE_W10C8.2(pop-1)

CBR:	CBG_04236(Cbr-pop-1) CBG_10973 CBG_10974 CBG_16744

CRQ:	GCK72_000853

NAI:	NECAME_05160

LOA:	LOAG_17858

TSP:

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_125630 Smp_148190

OVI:	T265_05265

EGL:	EGR_05129 EGR_09910

LLON:

NVE:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100199257(LOC100199257)

AQU:	100641322(Tcf)

» show all

Reference

PMID:19602480

Authors

Prokunina-Olsson L, Welch C, Hansson O, Adhikari N, Scott LJ, Usher N, Tong M, Sprau A, Swift A, Bonnycastle LL, Erdos MR, He Z, Saxena R, Harmon B, Kotova O, Hoffman EP, Altshuler D, Groop L, Boehnke M, Collins FS, Hall JL

Title

Tissue-specific alternative splicing of TCF7L2.

Journal

Hum Mol Genet 18:3795-804 (2009)
DOI:10.1093/hmg/ddp321

Sequence

[hsa:6934]

Reference

PMID:9065401

Authors

Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H

Title

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

Journal

Science 275:1784-7 (1997)
DOI:10.1126/science.275.5307.1784

Sequence

[hsa:6934]

All links

Gene (1408)   
   MGENES (246)   
   RefGene (1152)   
   OC (10)   
All databases (1408)   

Download RDF

ORTHOLOGY: K04492

Entry

K04492                      KO

Symbol

LEF1

Name

lymphoid enhancer-binding factor 1

Pathway

map04310

Wnt signaling pathway

map04390

Hippo signaling pathway

map04519

Cadherin signaling

map04520

Adherens junction

map04916

Melanogenesis

map04934

Cushing syndrome

map04936

Alcoholic liver disease

map05132

Salmonella infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05200

Pathways in cancer

map05210

Colorectal cancer

map05213

Endometrial cancer

map05215

Prostate cancer

map05216

Thyroid cancer

map05217

Basal cell carcinoma

map05221

Acute myeloid leukemia

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05412

Arrhythmogenic right ventricular cardiomyopathy

Disease

H00651

Hypohidrotic ectodermal dysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04492  LEF1; lymphoid enhancer-binding factor 1
   04390 Hippo signaling pathway
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    K04492  LEF1; lymphoid enhancer-binding factor 1
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04492  LEF1; lymphoid enhancer-binding factor 1
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04492  LEF1; lymphoid enhancer-binding factor 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05225 Hepatocellular carcinoma
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05226 Gastric cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05216 Thyroid cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05221 Acute myeloid leukemia
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05217 Basal cell carcinoma
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05215 Prostate cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05213 Endometrial cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05224 Breast cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04492  LEF1; lymphoid enhancer-binding factor 1
   04934 Cushing syndrome
    K04492  LEF1; lymphoid enhancer-binding factor 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04492  LEF1; lymphoid enhancer-binding factor 1
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04492  LEF1; lymphoid enhancer-binding factor 1

Genes

HSA:	51176(LEF1)

PTR:	461425(LEF1)

PPS:	100995847(LEF1)

GGO:	101140253(LEF1)

PON:	100447785(LEF1)

PPYG:

129035173(LEF1)

NLE:	100593051(LEF1)

HMH:	116479176(LEF1)

SSYN:

129492012(LEF1)

MCC:	695776(LEF1)

MCF:	101925349(LEF1)

MTHB:

126954934

MNI:	105486288(LEF1)

CSAB:

103236088(LEF1)

CATY:

105571411(LEF1)

PANU:

101017352(LEF1)

TGE:	112624710(LEF1)

MLEU:

105546575(LEF1)

RRO:	104670045(LEF1)

RBB:	108515891(LEF1)

TFN:	117085762(LEF1)

PTEH:

111547880(LEF1)

CANG:

105514397(LEF1)

CJC:	100399759(LEF1)

SBQ:	101047688(LEF1)

CIMI:

108289579(LEF1)

ANAN:

105706285(LEF1)

CSYR:

103252452(LEF1)

MMUR:

105872329(LEF1)

LCAT:

123627736(LEF1)

ERUF:

138375469(LEF1)

PCOQ:

105818969(LEF1)

OGA:	100958411(LEF1)

MMU:	16842(Lef1)

MCAL:

110290892(Lef1)

MPAH:

110319903(Lef1)

RNO:	161452(Lef1)

MCOC:

116093789(Lef1)

ANU:	117706912(Lef1)

ASYL:

127682687(Lef1)

MUN:	110553391(Lef1)

CGE:	100761200(Lef1)

MAUA:

101823226(Lef1)

PROB:

127223025(Lef1)

PLEU:

114682816(Lef1)

PMAV:

102906041(Lef1)

MORG:

121450203(Lef1)

MFOT:

126509833

AAMP:

119800683(Lef1)

CNL:	130889496(Lef1)

NGI:	103742515(Lef1)

HGL:	101711023(Lef1)

CPOC:

100716066(Lef1)

CCAN:

109688935

DORD:

105991153(Lef1)

DSP:	122127220(Lef1)

DMER:

138826977(Lef1)

PLOP:

125341448(Lef1)

NCAR:

124994528

SVUL:

306646553(ACX6B4_008985) 306669547(LEF1)

MMMA:

107141378(Lef1)

ITI:	101971761(Lef1)

SCIL:

308655108(LEF1)

MAVE:

308264624(LEF1)

OCU:

100352691

OPI:	101525298(LEF1)

OCZ:	121147532(LEF1)

TUP:	102474621(LEF1)

GVR:	103593743(LEF1)

CFA:	478507(LEF1)

CLUD:

112671621(LEF1)

VVP:	112934208(LEF1)

VLG:	121493895(LEF1)

NPO:	129521205(LEF1)

AML:	100465982(LEF1)

UMR:	103661728(LEF1)

UAH:	113255544(LEF1)

UAR:	123793375(LEF1)

ELK:

111154120

LLV:

125093264

MPUF:

101689480(LEF1)

MNP:	132002001(LEF1)

MLK:	131829467(LEF1)

NVS:	122889282(LEF1)

MMAQ:

308339035(LEF1)

ORO:	101372325(LEF1)

EJU:	114222653(LEF1)

ZCA:	113925268(LEF1)

MLX:	118027079(LEF1)

MANO:

123848331(LEF1)

NSU:	110575521(LEF1)

LWW:	102737827(LEF1)

FCA:	101088077(LEF1)

PYU:	121031433(LEF1)

PCOO:

112858040(LEF1)

PBG:	122477660(LEF1)

PVIV:

125163472(LEF1)

LRUF:

124520997

LGF:	123594191(LEF1)

AJU:

106983664

PTG:	102970026(LEF1)

PPAD:

109247814(LEF1)

PUC:

125923001

PLEZ:

122217968(LEF1)

HHV:	120236146(LEF1)

CCRU:

144243404(LEF1)

BTA:	535399(LEF1)

BOM:	102266946(LEF1)

BIU:	109560266(LEF1)

BJV:	133249275(LEF1)

BBUB:

102409520(LEF1)

BKE:	129657584(LEF1)

BBIS:

105002090(LEF1)

CHX:	100860901(LEF1)

OAS:	780521(LEF1)

OCAN:

138442093(LEF1)

BTAX:

128049642(LEF1)

CSUM:

138081763(LEF1)

ODA:	120861741(LEF1)

CCAD:

122422034(LEF1)

MREE:

136147821(LEF1)

OVR:	110142661(LEF1)

MBEZ:

129561748(LEF1)

SSC:	100170126(LEF1)

CFR:	102510619(LEF1)

CBAI:

105067944(LEF1)

CDK:	105105289(LEF1)

VPC:	102541243(LEF1)

BACU:

103020844(LEF1)

BMUS:

118896149(LEF1)

LVE:	103068879(LEF1)

OOR:	101287631(LEF1)

LALB:

132519452(LEF1)

GMF:	115857233(LEF1)

DDP:	132425554(LEF1)

SCOO:

307185737(LEF1)

PCRS:

137223507(LEF1)

DLE:	111171490(LEF1)

PCAD:

102996605(LEF1)

PSIU:

116753891(LEF1)

PPHC:

136123507(LEF1)

NASI:

112397669(LEF1)

HAMP:

307059229(LEF1)

ECB:	100072938(LEF1)

EPZ:	103557035(LEF1)

EAI:	106829814(LEF1)

MYB:	102255910(LEF1)

MYD:	102767379(LEF1)

MMYO:

118673131(LEF1)

MLF:	102439262(LEF1)

MDT:	132214590(LEF1)

MYUM:

139022398(LEF1)

PKL:	118702904(LEF1)

EFUS:

103293875(LEF1)

POTS:

308253626(LEF1)

MNA:	107538292(LEF1)

DRO:	112321441(LEF1)

SHON:

118977082(LEF1)

AJM:	119061436(LEF1)

PDIC:

114492280(LEF1)

PHAS:

123806910(LEF1)

MMF:	118637343(LEF1)

PPAM:

129085299(LEF1)

HAI:	109379461(LEF1)

RFQ:	117022359(LEF1)

RHII:

308500802(LEF1)

PALE:

102886933(LEF1)

PGIG:

120591231(LEF1)

PVP:	105293004(LEF1)

RAY:	107511497(LEF1)

MJV:	108405595(LEF1)

TOD:	119242944(LEF1)

SARA:

101547696(LEF1)

SFUM:

130023479(LEF1)

SETR:

126027890(LEF1)

LAV:	100658960(LEF1)

TMU:

101345125

ETF:	101645834(LEF1)

DNM:	101428006(LEF1)

MDO:	100011783(LEF1)

SHR:	100934638(LEF1)

AFZ:

127539946

PCW:	110218610(LEF1)

TVP:	118855312(LEF1)

PBRV:

138166424(LEF1)

MLAO:

141517576(LEF1)

OAA:	100079818(LEF1)

TACU:

119935615(LEF1)

GGA:	395865(LEF1)

PCOC:

116238078(LEF1)

MGP:	100542839(LEF1)

CJO:	107313267(LEF1)

TPAI:

128079992(LEF1)

LMUT:

125692117(LEF1)

NMEL:

110398346(LEF1)

APLA:

101792052(LEF1)

AACU:

137856490(LEF1)

OJA:	118166514(LEF1)

BCLA:

308443058(LEF1)

ACYG:

106038656(LEF1)

ABRC:

308194763(LEF1)

CATA:

118246221(LEF1)

AFUL:

116489255(LEF1)

TGU:	100228376(LEF1)

LSR:	110468005(LEF1)

VMC:	128806463(LEF1)

VCHA:

128787131(LEF1)

AIB:	137472383(LEF1)

SCAN:

103826009(LEF1)

PMOA:

120502824(LEF1)

OTC:	121331416(LEF1)

PRUF:

121360221(LEF1)

ATRC:

139592221(LEF1)

MATE:

118686106(LEF1)

MAEN:

136555455(LEF1)

GFR:	102034937(LEF1)

FAB:	101821185(LEF1)

OMA:	130252146(LEF1)

PHI:	102109576(LEF1)

PMAJ:

107203557(LEF1)

CCAE:

111928334(LEF1)

CCW:	104697293(LEF1)

CBRC:

103617392(LEF1)

ACOE:

138109615(LEF1)

ETL:	114057906(LEF1)

ZAB:	102060741(LEF1)

ZLE:	135446725(LEF1)

ACHL:

103808312(LEF1)

SVG:	106854401(LEF1)

MMEA:

130576220 130581148

HRT:	120753290(LEF1)

SATI:

136360514(LEF1)

CFAI:

136291306(LEF1)

CCIC:

134044534(LEF1)

NNT:	104411041(LEF1)

SHAB:

115610292(LEF1)

POCC:

134173011(LEF1)

FPG:	101917929(LEF1)

FCH:	102050307(LEF1)

FRS:	119144915(LEF1)

ACUN:

113479673(LEF1)

ANOC:

141960281(LEF1)

SURA:

141942843(LEF1)

TALA:

104357711(LEF1)

ACHC:

115343254(LEF1)

HALD:

104314291(LEF1)

HLE:	104843344(LEF1)

AGEN:

126044961

HHAR:

128135773(LEF1)

BBUT:

142036591(LEF1)

GCL:

127015863

CSTI:

104558670(LEF1)

LDI:	104353941(LEF1)

MNB:	103777011(LEF1)

DPUB:

104301797(LEF1)

PPUS:

135178027(LEF1)

IIN:	128968663(LEF1)

AVIT:

104274896(LEF1)

EGZ:	104135527(LEF1)

NNI:	104021166(LEF1)

PCRI:

104034615(LEF1)

PCAO:

104042542(LEF1)

PARX:

142056227(LEF1)

PADL:

103919538(LEF1)

AFOR:

103894233(LEF1)

FGA:

104083813

CBOR:

142082084(LEF1)

GSTE:

104254847(LEF1)

CBOY:

140651580(LEF1)

MAME:

142409335(LEF1)

CLV:	102084626(LEF1)

CNIC:

135987994(LEF1)

NMAY:

308039952(LEF1)

MUI:	104543451(LEF1)

PGUU:

104463233(LEF1)

PLET:

104622331(LEF1)

EHS:	104516011(LEF1)

CMAC:

104483274(TCF7)

CUCA:

104062883(LEF1)

PCUR:

138719934(LEF1)

TEO:

104377670

BREG:

104637927(LEF1)

GAME:

129206036(LEF1)

OHA:	104327260(LEF1)

ACAR:

104518792(LEF1)

CEUR:

306717592(LEF1)

CPEA:

104394492(LEF1)

CVF:	104286847(LEF1)

RTD:	128910491(LEF1)

CRID:

134516254(LEF1)

LMIC:

141743831(LEF1)

NARQ:

141465090(LEF1)

AAM:	106491833(LEF1)

AROW:

112972206(LEF1)

NPD:	112957317(LEF1)

TGT:	104578540(LEF1)

DNE:	112987873(LEF1)

SCAM:

104153503(LEF1)

ASN:	102385539(LEF1)

AMJ:	102560337(LEF1)

CPOO:

109309400(LEF1)

GGN:	109301061(LEF1)

PSS:	102456780(LEF1)

CIZ:	142012143(LEF1)

CMY:	102930185(LEF1)

CCAY:

125635259(LEF1)

LKP:	140910295(LEF1)

NDS:	141986331(LEF1)

DCC:	119854349(LEF1)

CPIC:

101953582(LEF1)

TST:	117878225(LEF1)

EOB:	135879786(LEF1)

CABI:

116837678(LEF1)

MRV:	120406221(LEF1)

EMQ:	137166457(LEF1)

ACS:	100556215(lef1)

ASAO:

132776935(LEF1)

PVT:	110080460(LEF1)

SUND:

121931875(LEF1)

PBI:	103064656(LEF1)

PMUR:

107302616(LEF1)

CTIG:

120308252(LEF1)

TSR:	106556004(LEF1)

PGUT:

117679923(LEF1)

PCAE:

139320672(LEF1)

APRI:

131192571 131203264(LEF1)

PTEX:

113434797(LEF1)

NSS:	113412826(LEF1)

VKO:	123023106(LEF1)

PMUA:

114603846(LEF1)

PRAF:

128421275(LEF1)

ZVI:	118083338(LEF1)

HCG:	128326173(LEF1)

GJA:	107123114(LEF1)

STOW:

125439978(LEF1)

EMC:	129337067(LEF1)

XLA:	398238(lef1.L) 779101(lef1.S)

XTR:	100493178(lef1)

NPR:	108785415(LEF1) 108801973

RTEM:

120917892(LEF1)

ACAT:

141110642(LEF1)

PADS:

140326785(LEF1)

BBUF:

120989930(LEF1)

BGAR:

122920359(LEF1)

DTC:	141086174(LEF1)

HSQ:	130361420(LEF1)

PCOB:

134910752(LEF1)

MUO:	115461172(LEF1)

GSH:	117365667(LEF1)

DRE:	30701(lef1)

DAES:

130225604(lef1)

SRX:	107729373 107757012

SANH:

107676173 107684275

SGH:	107583218(lef1) 107594427

CCAR:

109094918(lef1)

CAUA:

113044020 113044058 113044954

CGIB:

127948992 128017683

PTET:

122353119(lef1)

LROH:

127170696(lef1)

GRF:	141336525(lef1)

OMC:	131549781(lef1)

PPRM:

120491182(lef1)

RKG:	130087325(lef1)

SCEP:

307154677(lef1)

MAMB:

125271927(lef1)

CIDE:

127516640

CERY:

137032206(lef1)

MASI:

127444095 127445071

TROS:

130552707(lef1)

TDW:	130412426(lef1)

MANU:

129444131(lef1)

PDAB:

135785806(lef1)

IPU:

108262963

IFU:	128606021(lef1)

PHYP:

113538151(lef1)

SMEO:

124377280(lef1)

TFD:	113642358(lef1)

TVC:	132847602(lef1)

CGAR:

128517000(lef1)

NGRA:

132889710(lef1)

TRN:	134314641(lef1)

AMEX:

103033630(lef1)

CMAO:

118810856(lef1)

EEE:	113568617(lef1)

CHAR:

105903964(lef1)

SPIL:

134075161(lef1)

ASAD:

121719638(lef1)

TRU:	101064872(lef1) 115251054

TFS:	130527750(lef1)

TNG:	GSTEN00033451G001

NCC:

104953587

TBEN:

117482301(lef1)

CGOB:

115010760(lef1)

PGEO:

117449389(lef1)

EMAC:

134864343(lef1)

ELY:	117255366(lef1)

EFO:	125884388(lef1)

PLEP:

121942444(lef1)

SLUC:

116034295(lef1)

SVIT:

144525173(lef1)

ECRA:

117957879(lef1)

ESP:	116670487(lef1)

PFLV:

114567774(lef1)

PFLT:

120564034(lef1)

GAT:	120825743(lef1)

PPUG:

119217776(lef1)

AFB:	129095654(lef1)

CLUM:

117733594(lef1)

PSWI:

130190413(lef1)

CANA:

137792960(lef1)

TBU:	306737876(lef1)

CVE:	137885155(lef1)

AMIR:

142949606(lef1)

MSAM:

119898915(lef1) 119898916

SCHU:

122872868(lef1)

EARM:

139296881(lef1)

CUD:	121508857(lef1)

SPUL:

138594704(lef1)

LMIX:

132990091(lef1)

HTC:	141804626(lef1)

ALAT:

119020711(lef1)

ASTR:

137600114(lef1)

PKLU:

139198816(lef1)

LCO:	104927262(lef1)

AMMM:

307252506(lef1)

MZE:	101464688(lef1)

ONL:	100704365(lef1)

OAU:	116330136(lef1)

OLA:	101167344(lef1)

OML:	112157252(lef1)

CSAI:

133440140(lef1)

XMA:	102226301(lef1) 111609564

XCO:	114144420(lef1) 114149416

XHE:	116719693(lef1)

PRET:

103472749(lef1)

PFOR:

103143923(lef1)

PLAI:

106958163(lef1)

PMEI:

106930845(lef1)

GAF:	122829090(lef1)

PPRL:

129351107(lef1)

CVG:	107094620(lef1)

CTUL:

119779063(lef1)

GMU:	124868243(lef1)

NFU:	107375038(lef1)

KMR:	108230929(lef1)

ALIM:

106517066(lef1)

NWH:	119422647(lef1)

LTU:	140305923(lef1)

MCEP:

125003806(lef1)

AOCE:

111586156(lef1)

EJA:	138208821(lef1)

BFRE:

138615607(lef1)

LCF:

108888246

CSEM:

103383851(lef1) 103384774 107988365

POV:	109626192 109626206 109638362(lef1)

SSEN:

122770862(lef1)

SSOE:

131466464(lef1) 131468142

HHIP:

117768294(lef1)

HSP:	118123659(lef1)

PPLT:

128437276(lef1)

SMAU:

118311848(lef1)

SDU:	111236636(lef1)

SLAL:

111671174(lef1)

XGL:	120800237(lef1)

HCQ:	109511075(lef1) 109517272

SSCV:

125969039(lef1)

SBIA:

133504478 133505552(lef1)

PEE:	133404502(lef1)

PTAO:

133476854(lef1)

BPEC:

110165341(lef1)

ENY:	140377057(lef1)

MALB:

109955531(lef1) 109972141

BSPL:

114862393(lef1)

SJO:	128380243(lef1)

SSCO:

133992403(lef1)

TTY:	137179846(lef1)

GMH:	115540168(lef1)

SASA:

106602294 106610340(lef1)

STRU:

115191730(lef1)

OTW:	112239252(lef1)

OMY:	110497329 110534562

OGO:

124001502

OKI:	109876660(lef1)

OKE:	118373433(lef1)

OMM:	135507062(lef1)

OCLA:

139419062 139419068 139419102

SNH:	120034764 120035026(lef1)

SFON:

129845919 129845924(lef1)

CCLU:

121580693(lef1)

ELS:	105020989(lef1)

SFM:	108924316 108936677

PKI:	111837376(lef1) 111852095

AANG:

118226723(lef1) 118232500

AROT:

135254748(lef1) 135260093

CCOG:

133131367(lef1) 133135604

LOC:	102686059(lef1)

PSPA:

121296434 121321759(lef1)

ARUT:

117408361 117420543

PSEX:

120532281(lef1)

LCM:	102354030(LEF1)

CMK:

103182161

RTP:	109922552(lef1)

CPLA:

122539466(lef1)

CPUN:

140485610(lef1)

HOC:	132833260(lef1)

SCAU:

119963491(lef1)

LERI:

129701019(lef1)

HAKA:

140726306(lef1)

LPOL:

106470972

HRO:	HELRODRAFT_107147

» show all

Reference

PMID:10756202

Authors

Hovanes K, Li TW, Waterman ML

Title

The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing.

Journal

Nucleic Acids Res 28:1994-2003 (2000)
DOI:10.1093/nar/28.9.1994

Sequence

[hsa:51176]

Reference

PMID:17143293

Authors

Arce L, Yokoyama NN, Waterman ML

Title

Diversity of LEF/TCF action in development and disease.

Journal

Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

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Gene (319)   
   MGENES (89)   
   RefGene (224)   
   OC (6)   
All databases (319)   

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