KEGG   ORTHOLOGY: K02620
Entry
K02620                      KO                                     
Symbol
TCF7, TCF-1
Name
transcription factor 7
Pathway
map04310  Wnt signaling pathway
map04390  Hippo signaling pathway
map04520  Adherens junction
map04550  Signaling pathways regulating pluripotency of stem cells
map04916  Melanogenesis
map04934  Cushing syndrome
map04936  Alcoholic liver disease
map05132  Salmonella infection
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05213  Endometrial cancer
map05215  Prostate cancer
map05216  Thyroid cancer
map05217  Basal cell carcinoma
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
   04390 Hippo signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K02620  TCF7, TCF-1; transcription factor 7
   04550 Signaling pathways regulating pluripotency of stem cells
    K02620  TCF7, TCF-1; transcription factor 7
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K02620  TCF7, TCF-1; transcription factor 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05225 Hepatocellular carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05226 Gastric cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05216 Thyroid cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05221 Acute myeloid leukemia
    K02620  TCF7, TCF-1; transcription factor 7
   05217 Basal cell carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05215 Prostate cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05213 Endometrial cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05224 Breast cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02620  TCF7, TCF-1; transcription factor 7
   05165 Human papillomavirus infection
    K02620  TCF7, TCF-1; transcription factor 7
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K02620  TCF7, TCF-1; transcription factor 7
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K02620  TCF7, TCF-1; transcription factor 7
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K02620  TCF7, TCF-1; transcription factor 7
   04934 Cushing syndrome
    K02620  TCF7, TCF-1; transcription factor 7
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02620  TCF7, TCF-1; transcription factor 7
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K02620  TCF7, TCF-1; transcription factor 7
Genes
HSA: 6932(TCF7)
PTR: 745839(TCF7)
PPS: 100980839(TCF7)
GGO: 101149731(TCF7)
PON: 100461234(TCF7)
PPYG: 129036888(TCF7)
NLE: 100595737(TCF7)
HMH: 116471505(TCF7)
SSYN: 129457838(TCF7)
MCC: 710234(TCF7)
MCF: 102142248(TCF7)
MTHB: 126955989
MNI: 105467144(TCF7)
CSAB: 103244543(TCF7)
CATY: 105599768(TCF7)
PANU: 101024089(TCF7)
TGE: 112626303(TCF7)
MLEU: 105531321(TCF7)
RRO: 104659811(TCF7)
RBB: 108529562(TCF7)
TFN: 117065864(TCF7)
PTEH: 111529175(TCF7)
CANG: 105518212(TCF7)
CJC: 100399154(TCF7)
SBQ: 101029076(TCF7)
CIMI: 108307147(TCF7)
ANAN: 105708982(TCF7)
CSYR: 103268315(TCF7)
MMUR: 105869975(TCF7)
LCAT: 123637773(TCF7)
PCOQ: 105816027(TCF7)
OGA: 100947392(TCF7)
MMU: 21414(Tcf7)
MCAL: 110304948(Tcf7)
MPAH: 110332085(Tcf7)
RNO: 363595(Tcf7)
MCOC: 116077224(Tcf7)
ANU: 117710774(Tcf7)
MUN: 110549622(Tcf7)
CGE: 100757390(Tcf7)
MAUA: 101823261(Tcf7)
PROB: 127219310(Tcf7)
PLEU: 114683055(Tcf7)
MORG: 121456269(Tcf7)
MFOT: 126510979
AAMP: 119812304(Tcf7)
NGI: 103729786(Tcf7)
HGL: 101707882(Tcf7)
CPOC: 100712802(Tcf7)
CCAN: 109689465(Tcf7)
DORD: 105996789(Tcf7)
DSP: 122115432(Tcf7)
PLOP: 125342174(Tcf7)
NCAR: 124986637
MMMA: 107148128(Tcf7)
OCU: 100339216
OPI: 101526730(TCF7)
TUP: 102484318(TCF7)
GVR: 103592399(TCF7)
CFA: 481506(TCF7)
CLUD: 112650538(TCF7)
VVP: 112917059(TCF7)
VLG: 121495797(TCF7)
NPO: 129494859(TCF7)
AML: 100476528(TCF7)
UMR: 103663815(TCF7)
UAH: 113261735(TCF7)
UAR: 123790349(TCF7)
ELK: 111141244
LLV: 125099902
MPUF: 101678117(TCF7)
MNP: 132028516(TCF7)
MLK: 131832039(TCF7)
NVS: 122891699(TCF7)
ORO: 101376237(TCF7)
EJU: 114209512(TCF7)
ZCA: 113928407(TCF7)
MLX: 118016638(TCF7)
NSU: 110590995(TCF7)
LWW: 102733939(TCF7)
FCA: 101098768(TCF7)
PYU: 121010702(TCF7)
PCOO: 112861082(TCF7)
PBG: 122487396(TCF7)
PVIV: 125154231(TCF7)
LRUF: 124515627
PTG: 102957988(TCF7)
PPAD: 109250863(TCF7)
PUC: 125935489
AJU: 106984911
HHV: 120238500(TCF7)
BTA: 782690(TCF7)
BOM: 102266633(TCF7)
BIU: 109562015(TCF7)
BBUB: 102408996(TCF7)
BBIS: 104991933(TCF7)
CHX: 102173736(TCF7)
OAS: 101101980(TCF7)
BTAX: 128050871(TCF7)
ODA: 120863661(TCF7)
CCAD: 122439921(TCF7)
MBEZ: 129558296(TCF7)
SSC: 100512951(TCF7)
CFR: 102519063(TCF7)
CBAI: 105082121(TCF7)
CDK: 105090254(TCF7)
VPC: 102537589(TCF7)
BACU: 103018264(TCF7)
BMUS: 118892102(TCF7)
LVE: 103074150(TCF7)
OOR: 101289599(TCF7)
DLE: 111182442(TCF7)
PCAD: 102992878(TCF7)
PSIU: 116752164(TCF7)
NASI: 112399678(TCF7)
ECB: 100072786(TCF7)
EPZ: 103543120(TCF7)
EAI: 106834657(TCF7)
MYB: 102250528(TCF7)
MYD: 102757003(TCF7)
MMYO: 118657631(TCF7)
MLF: 102433022(TCF7)
MDT: 132235660(TCF7)
PKL: 118711889(TCF7)
EFUS: 103286726(TCF7)
MNA: 107525397(TCF7)
DRO: 112318180(TCF7)
SHON: 118990084(TCF7)
AJM: 119037608(TCF7)
PDIC: 114509934(TCF7)
PHAS: 123811661(TCF7)
MMF: 118643629(TCF7)
PPAM: 129066685(TCF7)
HAI: 109382635(TCF7)
RFQ: 117017071(TCF7)
PALE: 102885788(TCF7)
PGIG: 120581289(TCF7)
PVP: 105293567(TCF7)
RAY: 107506797(TCF7)
MJV: 108406081(TCF7)
TOD: 119243471(TCF7)
SARA: 101540913(TCF7)
SETR: 126027752(TCF7)
LAV: 100663559(TCF7)
TMU: 101350837
ETF: 101657040(TCF7)
DNM: 101411457(TCF7)
MDO: 100017589(TCF7)
GAS: 123237636(TCF7)
SHR: 100930141(TCF7)
AFZ: 127549825
PCW: 110211723(TCF7)
TVP: 118841366(TCF7)
OAA: 100082332(TCF7)
GGA: 395229(TCF7)
PCOC: 116232216(TCF7)
MGP: 100544924(TCF7)
CJO: 107320225(TCF7)
TPAI: 128083971(TCF7)
LMUT: 125700061(TCF7)
NMEL: 110405287(TCF7)
APLA: 101803610(TCF7)
ACYG: 106032766(TCF7)
CATA: 118254957(TCF7)
AFUL: 116495052(TCF7)
TGU: 100221008(TCF7)
LSR: 110481074(TCF7)
SCAN: 103817470(TCF7)
PMOA: 120498623(TCF7)
OTC: 121332492(TCF7)
PRUF: 121361301(TCF7)
GFR: 102036749(TCF7)
FAB: 101820491(TCF7)
OMA: 130258940(TCF7)
PHI: 102110510(TCF7)
PMAJ: 107210639(TCF7)
CCAE: 111935599(TCF7)
CCW: 104683724(TCF7)
CBRC: 103614692(TCF7)
ETL: 114063910(TCF7)
ZAB: 102061135(TCF7)
ZLE: 135453706(TCF7)
ACHL: 103807821(TCF7)
SVG: 106862626(TCF7)
MMEA: 130576571(TCF7)
HRT: 120759054(TCF7)
SATI: 136367426(TCF7)
FPG: 101919678(TCF7)
FCH: 102058554(TCF7)
NNT: 104408659
SHAB: 115615905(TCF7)
ACUN: 113485114(TCF7)
TALA: 104365223(TCF7)
ACHC: 115334089(TCF7)
HLE: 104839072(TCF7)
AGEN: 126051116
GCL: 127021964
CSTI: 104558021(TCF7)
LDI: 104346558
DPUB: 104310141(TCF7)
AVIT: 104274978(TCF7)
BRHI: 104496022(TCF7)
EGZ: 104133478(TCF7)
NNI: 104012004(TCF7)
PCAO: 104051181(TCF7)
PADL: 103915850(TCF7)
AFOR: 103904439(TCF7)
CLV: 102094656(TCF7)
MUI: 104543267
PGUU: 104459059
EHS: 104509814(TCF7)
CUCA: 104060926(TCF7)
TEO: 104383729
OHA: 104338062(TCF7)
ACAR: 104529243
CPEA: 104386840(TCF7)
CVF: 104292051(TCF7)
RTD: 128915932(TCF7)
AAM: 106487174(TCF7)
AROW: 112964702(TCF7)
NPD: 112952974(TCF7)
TGT: 104572832
DNE: 112994146(TCF7)
ASN: 102383175(TCF7)
AMJ: 102576120(TCF7)
CPOO: 109310088(TCF7)
GGN: 109289961(TCF7)
PSS: 102446665(TCF7)
CMY: 102943166(TCF7)
CCAY: 125641612(TCF7)
DCC: 119860601(TCF7)
CPIC: 101937399(TCF7)
TST: 117882270(TCF7)
CABI: 116826639(TCF7)
MRV: 120370469(TCF7)
ACS: 100554608(tcf7)
ASAO: 132768881(TCF7)
PVT: 110079405(TCF7)
SUND: 121922739(TCF7)
PBI: 103067042(TCF7)
PMUR: 107294908(TCF7)
CTIG: 120305514(TCF7)
TSR: 106542632(TCF7)
PGUT: 117656083(TCF7)
PTEX: 113433747(TCF7)
NSS: 113425241(TCF7)
VKO: 123035726(TCF7)
PMUA: 114591268(TCF7)
PRAF: 128407866(TCF7)
ZVI: 118080356(TCF7)
HCG: 128344517(TCF7)
GJA: 107125983(TCF7)
STOW: 125429787(TCF7)
EMC: 129328416(TCF7)
XLA: 398658(tcf7.S)
XTR: 395061(tcf7)
NPR: 108792126(TCF7)
BBUF: 121009361(TCF7)
BGAR: 122928266(TCF7)
MUO: 115475827(TCF7)
GSH: 117351675(TCF7)
DRE: 497649(tcf7)
SRX: 107728269 107742437(tcf7)
SANH: 107661683(tcf7) 107692971
CCAR: 109048020
PTET: 122326316(tcf7)
LROH: 127152460(tcf7)
OMC: 131528515(tcf7)
PPRM: 120473621(tcf7)
RKG: 130077508(tcf7)
MAMB: 125253085(tcf7)
CIDE: 127503210
CERY: 137012083(tcf7)
TROS: 130570657(tcf7)
TDW: 130408426(tcf7)
MANU: 129423732(tcf7)
IPU: 108278866
IFU: 128621996(tcf7)
PHYP: 113535749
SMEO: 124397852(tcf7)
TFD: 113646522(tcf7)
TVC: 132860516(tcf7)
TRN: 134330139(tcf7)
AMEX: 103045826(tcf7)
CMAO: 118820197(tcf7)
EEE: 113578029(tcf7)
CHAR: 105893198(tcf7)
TRU: 101076516(tcf7)
TFS: 130537242(tcf7)
LCO: 104924428
NCC: 104960861(tcf7)
TBEN: 117490735(tcf7)
CGOB: 115018803(tcf7)
PGEO: 117458286(tcf7)
GACU: 117540208(tcf7)
EMAC: 134871756(tcf7) 134876197
ELY: 117245747 117268549(tcf7)
EFO: 125898881(tcf7)
PLEP: 121952129(tcf7)
SLUC: 116055911(tcf7) 118493643
ECRA: 117955094(tcf7)
ESP: 116679407 116700180(tcf7)
PFLV: 114566424(tcf7)
GAT: 120821561(tcf7)
PPUG: 119215586(tcf7)
AFB: 129113131(tcf7)
CLUM: 117742499(tcf7)
PSWI: 130211081(tcf7)
MSAM: 119895287(tcf7)
SCHU: 122888511(tcf7)
CUD: 121518698(tcf7)
ALAT: 119014087 119031550(tcf7)
MZE: 101469770(tcf7)
ONL: 100710520(tcf7)
OAU: 116315805(tcf7)
OML: 112137216 112142310(tcf7)
CSAI: 133460035(tcf7)
XMA: 102221228(tcf7) 111610761
XCO: 114152465(tcf7) 114157642
XHE: 116728111(tcf7) 116732626
PRET: 103460015(tcf7) 103480959
PFOR: 103155760(tcf7)
PLAI: 106935267(tcf7) 106958964
PMEI: 106910477 106916700(tcf7)
GAF: 122820847 122844686(tcf7)
PPRL: 129373420(tcf7)
CVG: 107085909(tcf7)
CTUL: 119797145 119797952(tcf7)
GMU: 124876424(tcf7) 124880979
NFU: 107378492 107386837(tcf7)
KMR: 108238102(tcf7)
ALIM: 106524564(tcf7) 106532889
NWH: 119420469(tcf7)
AOCE: 111566135
MCEP: 125020943(tcf7)
CSEM: 103394864(tcf7)
POV: 109635808(tcf7)
SSEN: 122776845 122779518(tcf7)
HSP: 118102942 118121778(tcf7)
PPLT: 128429971 128457663(tcf7)
SMAU: 118300136(tcf7)
LCF: 108893669
SDU: 111234495(tcf7)
SLAL: 111659992(tcf7)
XGL: 120803038(tcf7)
SSCV: 125982336
SBIA: 133492132(tcf7)
PEE: 133415647(tcf7)
MALB: 109966812(tcf7)
BSPL: 114869348(tcf7)
SJO: 128371950(tcf7)
OMY: 101268913(tcf7) 110537729
SNH: 120044389(tcf7) 120056778
ELS: 105026693
PKI: 111839551
AANG: 118236295(tcf7)
LOC: 102694215(tcf7)
PSEX: 120542075(tcf7)
LCM: 102350321(TCF7)
CMK: 103183678(tcf7)
CPLA: 122556583(tcf7)
HOC: 132823436(tcf7)
LERI: 129701802(tcf7)
PMRN: 116956914
APLN: 108741021
VDE: 111250602
DFR: 124496842
GAE: 121391070
MYI: 110453946
ATEN: 116297634
HSY: 130647411
RES: 135689380
 » show all
Reference
PMID:1569101
  Authors
van de Wetering M, Oosterwegel M, Holstege F, Dooyes D, Suijkerbuijk R, Geurts van Kessel A, Clevers H
  Title
The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.
  Journal
J Biol Chem 267:8530-6 (1992)
  Sequence
[hsa:6932]
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056
Reference
  Authors
Ioannidis V, Beermann F, Clevers H, Held W
  Title
The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.
  Journal
Nat Immunol 2:691-7 (2001)
DOI:10.1038/90623
  Sequence
[mmu:21414]

KEGG   ORTHOLOGY: K04492
Entry
K04492                      KO                                     
Symbol
LEF1
Name
lymphoid enhancer-binding factor 1
Pathway
map04310  Wnt signaling pathway
map04390  Hippo signaling pathway
map04520  Adherens junction
map04916  Melanogenesis
map04934  Cushing syndrome
map04936  Alcoholic liver disease
map05132  Salmonella infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05213  Endometrial cancer
map05215  Prostate cancer
map05216  Thyroid cancer
map05217  Basal cell carcinoma
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04492  LEF1; lymphoid enhancer-binding factor 1
   04390 Hippo signaling pathway
    K04492  LEF1; lymphoid enhancer-binding factor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04492  LEF1; lymphoid enhancer-binding factor 1
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04492  LEF1; lymphoid enhancer-binding factor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05225 Hepatocellular carcinoma
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05226 Gastric cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05216 Thyroid cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05221 Acute myeloid leukemia
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05217 Basal cell carcinoma
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05215 Prostate cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05213 Endometrial cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
   05224 Breast cancer
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04492  LEF1; lymphoid enhancer-binding factor 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04492  LEF1; lymphoid enhancer-binding factor 1
   04934 Cushing syndrome
    K04492  LEF1; lymphoid enhancer-binding factor 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04492  LEF1; lymphoid enhancer-binding factor 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04492  LEF1; lymphoid enhancer-binding factor 1
Genes
HSA: 51176(LEF1)
PTR: 461425(LEF1)
PPS: 100995847(LEF1)
GGO: 101140253(LEF1)
PON: 100447785(LEF1)
PPYG: 129035173(LEF1)
NLE: 100593051(LEF1)
HMH: 116479176(LEF1)
SSYN: 129492012(LEF1)
MCC: 695776(LEF1)
MCF: 101925349(LEF1)
MTHB: 126954934
MNI: 105486288(LEF1)
CSAB: 103236088(LEF1)
CATY: 105571411(LEF1)
PANU: 101017352(LEF1)
TGE: 112624710(LEF1)
MLEU: 105546575(LEF1)
RRO: 104670045(LEF1)
RBB: 108515891(LEF1)
TFN: 117085762(LEF1)
PTEH: 111547880(LEF1)
CANG: 105514397(LEF1)
CJC: 100399759(LEF1)
SBQ: 101047688(LEF1)
CIMI: 108289579(LEF1)
ANAN: 105706285(LEF1)
CSYR: 103252452(LEF1)
MMUR: 105872329(LEF1)
LCAT: 123627736(LEF1)
PCOQ: 105818969(LEF1)
OGA: 100958411(LEF1)
MMU: 16842(Lef1)
MCAL: 110290892(Lef1)
MPAH: 110319903(Lef1)
RNO: 161452(Lef1)
MCOC: 116093789(Lef1)
ANU: 117706912(Lef1)
MUN: 110553391(Lef1)
CGE: 100761200(Lef1)
MAUA: 101823226(Lef1)
PROB: 127223025(Lef1)
PLEU: 114682816(Lef1)
MORG: 121450203(Lef1)
MFOT: 126509833
AAMP: 119800683(Lef1)
NGI: 103742515(Lef1)
HGL: 101711023(Lef1)
CPOC: 100716066(Lef1)
CCAN: 109688935
DORD: 105991153(Lef1)
DSP: 122127220(Lef1)
PLOP: 125341448(Lef1)
NCAR: 124994528
MMMA: 107141378(Lef1)
OCU: 100352691
OPI: 101525298(LEF1)
TUP: 102474621(LEF1)
GVR: 103593743(LEF1)
CFA: 478507(LEF1)
CLUD: 112671621(LEF1)
VVP: 112934208(LEF1)
VLG: 121493895(LEF1)
NPO: 129521205(LEF1)
AML: 100465982(LEF1)
UMR: 103661728(LEF1)
UAH: 113255544(LEF1)
UAR: 123793375(LEF1)
ELK: 111154120
LLV: 125093264
MPUF: 101689480(LEF1)
MNP: 132002001(LEF1)
MLK: 131829467(LEF1)
NVS: 122889282(LEF1)
ORO: 101372325(LEF1)
EJU: 114222653(LEF1)
ZCA: 113925268(LEF1)
MLX: 118027079(LEF1)
NSU: 110575521(LEF1)
LWW: 102737827(LEF1)
FCA: 101088077(LEF1)
PYU: 121031433(LEF1)
PCOO: 112858040(LEF1)
PBG: 122477660(LEF1)
PVIV: 125163472(LEF1)
LRUF: 124520997
PTG: 102970026(LEF1)
PPAD: 109247814(LEF1)
PUC: 125923001
AJU: 106983664
HHV: 120236146(LEF1)
BTA: 535399(LEF1)
BOM: 102266946(LEF1)
BIU: 109560266(LEF1)
BBUB: 102409520(LEF1)
BBIS: 105002090(LEF1)
CHX: 100860901(LEF1)
OAS: 780521(LEF1)
BTAX: 128049642(LEF1)
ODA: 120861741(LEF1)
CCAD: 122422034(LEF1)
MBEZ: 129561748(LEF1)
SSC: 100170126(LEF1)
CFR: 102510619(LEF1)
CBAI: 105067944(LEF1)
CDK: 105105289(LEF1)
VPC: 102541243(LEF1)
BACU: 103020844(LEF1)
BMUS: 118896149(LEF1)
LVE: 103068879(LEF1)
OOR: 101287631(LEF1)
DLE: 111171490(LEF1)
PCAD: 102996605(LEF1)
PSIU: 116753891(LEF1)
NASI: 112397669(LEF1)
ECB: 100072938(LEF1)
EPZ: 103557035(LEF1)
EAI: 106829814(LEF1)
MYB: 102255910(LEF1)
MYD: 102767379(LEF1)
MMYO: 118673131(LEF1)
MLF: 102439262(LEF1)
MDT: 132214590(LEF1)
PKL: 118702904(LEF1)
EFUS: 103293875(LEF1)
MNA: 107538292(LEF1)
DRO: 112321441(LEF1)
SHON: 118977082(LEF1)
AJM: 119061436(LEF1)
PDIC: 114492280(LEF1)
PHAS: 123806910(LEF1)
MMF: 118637343(LEF1)
PPAM: 129085299(LEF1)
HAI: 109379461(LEF1)
RFQ: 117022359(LEF1)
PALE: 102886933(LEF1)
PGIG: 120591231(LEF1)
PVP: 105293004(LEF1)
RAY: 107511497(LEF1)
MJV: 108405595(LEF1)
TOD: 119242944(LEF1)
SARA: 101547696(LEF1)
SETR: 126027890(LEF1)
LAV: 100658960(LEF1)
TMU: 101345125
ETF: 101645834(LEF1)
DNM: 101428006(LEF1)
MDO: 100011783(LEF1)
SHR: 100934638(LEF1)
AFZ: 127539946
PCW: 110218610(LEF1)
TVP: 118855312(LEF1)
OAA: 100079818(LEF1)
GGA: 395865(LEF1)
PCOC: 116238078(LEF1)
MGP: 100542839(LEF1)
CJO: 107313267(LEF1)
TPAI: 128079992(LEF1)
LMUT: 125692117(LEF1)
NMEL: 110398346(LEF1)
APLA: 101792052(LEF1)
ACYG: 106038656(LEF1)
CATA: 118246221(LEF1)
AFUL: 116489255(LEF1)
TGU: 100228376(LEF1)
LSR: 110468005(LEF1)
SCAN: 103826009(LEF1)
PMOA: 120502824(LEF1)
OTC: 121331416(LEF1)
PRUF: 121360221(LEF1)
GFR: 102034937(LEF1)
FAB: 101821185(LEF1)
OMA: 130252146(LEF1)
PHI: 102109576(LEF1)
PMAJ: 107203557(LEF1)
CCAE: 111928334(LEF1)
CCW: 104697293(LEF1)
CBRC: 103617392(LEF1)
ETL: 114057906(LEF1)
ZAB: 102060741(LEF1)
ZLE: 135446725(LEF1)
ACHL: 103808312(LEF1)
SVG: 106854401(LEF1)
HRT: 120753290(LEF1)
SATI: 136360514(LEF1)
FPG: 101917929(LEF1)
FCH: 102050307(LEF1)
NNT: 104411041(LEF1)
SHAB: 115610292(LEF1)
ACUN: 113479673(LEF1)
TALA: 104357711(LEF1)
ACHC: 115343254(LEF1)
HALD: 104314291(LEF1)
HLE: 104843344(LEF1)
AGEN: 126044961
GCL: 127015863
CSTI: 104558670(LEF1)
LDI: 104353941(LEF1)
MNB: 103777011(LEF1)
DPUB: 104301797(LEF1)
AVIT: 104274896(LEF1)
EGZ: 104135527(LEF1)
NNI: 104021166(LEF1)
PCRI: 104034615(LEF1)
PCAO: 104042542(LEF1)
PADL: 103919538(LEF1)
AFOR: 103894233(LEF1)
FGA: 104083813
GSTE: 104254847(LEF1)
CLV: 102084626(LEF1)
MUI: 104543451(LEF1)
PGUU: 104463233(LEF1)
PLET: 104622331(LEF1)
EHS: 104516011(LEF1)
CMAC: 104483274(TCF7)
CUCA: 104062883(LEF1)
TEO: 104377670
BREG: 104637927(LEF1)
OHA: 104327260(LEF1)
ACAR: 104518792(LEF1)
CPEA: 104394492(LEF1)
CVF: 104286847(LEF1)
RTD: 128910491(LEF1)
AAM: 106491833(LEF1)
AROW: 112972206(LEF1)
NPD: 112957317(LEF1)
TGT: 104578540(LEF1)
DNE: 112987873(LEF1)
SCAM: 104153503(LEF1)
ASN: 102385539(LEF1)
AMJ: 102560337(LEF1)
CPOO: 109309400(LEF1)
GGN: 109301061(LEF1)
PSS: 102456780(LEF1)
CMY: 102930185(LEF1)
CCAY: 125635259(LEF1)
DCC: 119854349(LEF1)
CPIC: 101953582(LEF1)
TST: 117878225(LEF1)
CABI: 116837678(LEF1)
MRV: 120406221(LEF1)
ACS: 100556215(lef1)
ASAO: 132776935(LEF1)
PVT: 110080460(LEF1)
SUND: 121931875(LEF1)
PBI: 103064656(LEF1)
PMUR: 107302616(LEF1)
CTIG: 120308252(LEF1)
TSR: 106556004(LEF1)
PGUT: 117679923(LEF1)
APRI: 131192571 131203264(LEF1)
PTEX: 113434797(LEF1)
NSS: 113412826(LEF1)
VKO: 123023106(LEF1)
PMUA: 114603846(LEF1)
PRAF: 128421275(LEF1)
ZVI: 118083338(LEF1)
HCG: 128326173(LEF1)
GJA: 107123114(LEF1)
STOW: 125439978(LEF1)
EMC: 129337067(LEF1)
XLA: 398238(lef1.L) 779101(lef1.S)
XTR: 100493178(lef1)
NPR: 108785415(LEF1) 108801973
RTEM: 120917892(LEF1)
BBUF: 120989930(LEF1)
BGAR: 122920359(LEF1)
MUO: 115461172(LEF1)
GSH: 117365667(LEF1)
DRE: 30701(lef1)
SGH: 107583218(lef1) 107594427
CCAR: 109046851
PTET: 122353119(lef1)
LROH: 127170696(lef1)
OMC: 131549781(lef1)
PPRM: 120491182(lef1)
RKG: 130087325(lef1)
MAMB: 125271927(lef1)
CIDE: 127516640
CERY: 137032206(lef1)
TROS: 130552707(lef1)
TDW: 130412426(lef1)
MANU: 129444131(lef1)
IPU: 108262963
IFU: 128606021(lef1)
PHYP: 113538151(lef1)
SMEO: 124377280(lef1)
TFD: 113642358(lef1)
TVC: 132847602(lef1)
TRN: 134314641(lef1)
AMEX: 103033630(lef1)
CMAO: 118810856(lef1)
EEE: 113568617(lef1)
CHAR: 105903964(lef1)
TRU: 101064872(lef1) 115251054
TFS: 130527750(lef1)
LCO: 104927262(lef1)
NCC: 104953587
TBEN: 117482301(lef1)
CGOB: 115010760(lef1)
PGEO: 117449389(lef1)
EMAC: 134864343(lef1)
ELY: 117255366(lef1)
EFO: 125884388(lef1)
PLEP: 121942444(lef1)
SLUC: 116034295(lef1)
ECRA: 117957879(lef1)
ESP: 116670487(lef1)
PFLV: 114567774(lef1)
GAT: 120825743(lef1)
PPUG: 119217776(lef1)
AFB: 129095654(lef1)
CLUM: 117733594(lef1)
PSWI: 130190413(lef1)
MSAM: 119898915(lef1) 119898916
SCHU: 122872868(lef1)
CUD: 121508857(lef1)
ALAT: 119020711(lef1)
MZE: 101464688(lef1)
ONL: 100704365(lef1)
OAU: 116330136(lef1)
OLA: 101167344(lef1)
OML: 112157252(lef1)
CSAI: 133440140(lef1)
XMA: 102226301(lef1) 111609564
XCO: 114144420(lef1) 114149416
XHE: 116719693(lef1)
PRET: 103472749(lef1)
PFOR: 103143923(lef1)
PLAI: 106958163(lef1)
PMEI: 106930845(lef1)
GAF: 122829090(lef1)
PPRL: 129351107(lef1)
CVG: 107094620(lef1)
CTUL: 119779063(lef1)
GMU: 124868243(lef1)
NFU: 107375038(lef1)
KMR: 108230929(lef1)
ALIM: 106517066(lef1)
NWH: 119422647(lef1)
AOCE: 111586156(lef1)
MCEP: 125003806(lef1)
SSEN: 122770862(lef1)
HHIP: 117768294(lef1)
HSP: 118123659(lef1)
PPLT: 128437276(lef1)
SMAU: 118311848(lef1)
LCF: 108888246
SDU: 111236636(lef1)
SLAL: 111671174(lef1)
XGL: 120800237(lef1)
SSCV: 125969039
SBIA: 133504478 133505552(lef1)
PEE: 133404502(lef1)
PTAO: 133476854(lef1)
BPEC: 110165341(lef1)
MALB: 109955531(lef1) 109972141
BSPL: 114862393(lef1)
SJO: 128380243(lef1)
SASA: 106602294 106610340(lef1)
STRU: 115191730(lef1)
OTW: 112239252(lef1)
OGO: 124001502
OKI: 109876660(lef1)
OKE: 118373433(lef1)
SNH: 120034764 120035026(lef1)
CCLU: 121580693(lef1)
ELS: 105020989(lef1)
PKI: 111837376(lef1) 111852095
AANG: 118226723(lef1) 118232500
LOC: 102686059(lef1)
PSPA: 121296434 121321759(lef1)
PSEX: 120532281(lef1)
LCM: 102354030(LEF1)
CMK: 103182161
RTP: 109922552(lef1)
CPLA: 122539466(lef1)
HOC: 132833260(lef1)
LERI: 129701019(lef1)
LPOL: 106470972
 » show all
Reference
  Authors
Hovanes K, Li TW, Waterman ML
  Title
The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing.
  Journal
Nucleic Acids Res 28:1994-2003 (2000)
DOI:10.1093/nar/28.9.1994
  Sequence
[hsa:51176]
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

KEGG   ORTHOLOGY: K04491
Entry
K04491                      KO                                     
Symbol
TCF7L2
Name
transcription factor 7-like 2
Pathway
map04310  Wnt signaling pathway
map04390  Hippo signaling pathway
map04520  Adherens junction
map04916  Melanogenesis
map04934  Cushing syndrome
map04936  Alcoholic liver disease
map05132  Salmonella infection
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05213  Endometrial cancer
map05215  Prostate cancer
map05216  Thyroid cancer
map05217  Basal cell carcinoma
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05412  Arrhythmogenic right ventricular cardiomyopathy
Disease
H00409  Type 2 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04491  TCF7L2; transcription factor 7-like 2
   04390 Hippo signaling pathway
    K04491  TCF7L2; transcription factor 7-like 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04491  TCF7L2; transcription factor 7-like 2
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04491  TCF7L2; transcription factor 7-like 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04491  TCF7L2; transcription factor 7-like 2
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05225 Hepatocellular carcinoma
    K04491  TCF7L2; transcription factor 7-like 2
   05226 Gastric cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05216 Thyroid cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05221 Acute myeloid leukemia
    K04491  TCF7L2; transcription factor 7-like 2
   05217 Basal cell carcinoma
    K04491  TCF7L2; transcription factor 7-like 2
   05215 Prostate cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05213 Endometrial cancer
    K04491  TCF7L2; transcription factor 7-like 2
   05224 Breast cancer
    K04491  TCF7L2; transcription factor 7-like 2
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04491  TCF7L2; transcription factor 7-like 2
   05165 Human papillomavirus infection
    K04491  TCF7L2; transcription factor 7-like 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04491  TCF7L2; transcription factor 7-like 2
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04491  TCF7L2; transcription factor 7-like 2
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04491  TCF7L2; transcription factor 7-like 2
   04934 Cushing syndrome
    K04491  TCF7L2; transcription factor 7-like 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04491  TCF7L2; transcription factor 7-like 2
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04491  TCF7L2; transcription factor 7-like 2
Genes
HSA: 6934(TCF7L2)
PTR: 450743(TCF7L2)
PPS: 100978424(TCF7L2)
GGO: 109025238(TCF7L2)
PON: 100434811(TCF7L2)
PPYG: 129045299(TCF7L2)
NLE: 100605701(TCF7L2)
HMH: 116483446(TCF7L2)
SSYN: 129466010(TCF7L2)
MCC: 701759(TCF7L2)
MCF: 102116470(TCF7L2)
MTHB: 126962827
MNI: 105467983(TCF7L2)
CSAB: 103216817(TCF7L2)
CATY: 105577906(TCF7L2)
PANU: 101026705(TCF7L2)
TGE: 112631247(TCF7L2)
MLEU: 105530146(TCF7L2)
RRO: 104664436(TCF7L2)
RBB: 108542456(TCF7L2)
TFN: 117066750(TCF7L2)
PTEH: 111538904(TCF7L2)
CANG: 105501828(TCF7L2)
CJC: 100406757(TCF7L2)
SBQ: 101037011(TCF7L2)
CIMI: 108311134
ANAN: 105714167(TCF7L2)
CSYR: 103256089(TCF7L2)
MMUR: 105875160(TCF7L2)
LCAT: 123649863(TCF7L2)
PCOQ: 105826013(TCF7L2)
OGA: 100943434(TCF7L2)
MMU: 21416(Tcf7l2)
MCAL: 110285273(Tcf7l2)
MPAH: 110313411(Tcf7l2)
RNO: 679869(Tcf7l2)
MCOC: 116104020(Tcf7l2)
ANU: 117718257(Tcf7l2)
MUN: 110545126(Tcf7l2)
CGE: 100758400(Tcf7l2)
MAUA: 101831174(Tcf7l2)
PROB: 127233545(Tcf7l2)
PLEU: 114697060(Tcf7l2)
MORG: 121453859(Tcf7l2)
MFOT: 126505923
AAMP: 119806595(Tcf7l2)
NGI: 103731749(Tcf7l2)
HGL: 101710380(Tcf7l2)
CPOC: 100715721(Tcf7l2)
CCAN: 109688561(Tcf7l2)
DORD: 105986725(Tcf7l2)
DSP: 122115716(Tcf7l2)
NCAR: 124984748
MMMA: 107149900(Tcf7l2)
OCU: 100358378
OPI: 101521047(TCF7L2)
TUP: 102472810(TCF7L2)
GVR: 103589124(TCF7L2)
CFA: 486894(TCF7L2)
CLUD: 112672346(TCF7L2)
VVP: 112916157(TCF7L2)
VLG: 121485032(TCF7L2)
NPO: 129493862(TCF7L2)
AML: 100467719(TCF7L2)
UMR: 103657263(TCF7L2)
UAH: 113251942(TCF7L2)
UAR: 123795969(TCF7L2)
ELK: 111145217
LLV: 125084325
MPUF: 101676452(TCF7L2)
MNP: 132016786(TCF7L2)
MLK: 131830678(TCF7L2)
NVS: 122901120(TCF7L2)
ORO: 101385846(TCF7L2)
ZCA: 113923025(TCF7L2)
MLX: 118026323(TCF7L2)
NSU: 110589494(TCF7L2)
LWW: 102745990(TCF7L2)
FCA: 101095618(TCF7L2)
PYU: 121037238(TCF7L2)
PCOO: 112854283(TCF7L2)
PBG: 122493255(TCF7L2)
PVIV: 125147670(TCF7L2)
LRUF: 124507146
PTG: 102961321(TCF7L2)
PPAD: 109272915(TCF7L2)
PUC: 125932981
AJU: 106974119
HHV: 120235337(TCF7L2)
BTA: 540481(TCF7L2)
BOM: 102272230(TCF7L2)
BIU: 109553057(TCF7L2)
BBUB: 102393101(TCF7L2)
BBIS: 105002610(TCF7L2)
CHX: 102180102(TCF7L2)
OAS: 101118068(TCF7L2)
BTAX: 128067999(TCF7L2)
ODA: 120873902(TCF7L2)
CCAD: 122445909(TCF7L2)
MBEZ: 129555340(TCF7L2)
SSC: 100153922(TCF7L2)
CFR: 102510763(TCF7L2)
CBAI: 105080737(TCF7L2)
CDK: 105091689(TCF7L2)
VPC: 102525508(TCF7L2)
BACU: 103010923(TCF7L2)
BMUS: 118882500(TCF7L2) 118888134
LVE: 103068781(TCF7L2)
OOR: 101288107(TCF7L2)
DLE: 111172300(TCF7L2)
PCAD: 102987858(TCF7L2)
PSIU: 116741601(TCF7L2)
NASI: 112406953(TCF7L2)
ECB: 100059146(TCF7L2)
EPZ: 103564289(TCF7L2)
EAI: 106848101(TCF7L2)
MYB: 102245737(TCF7L2)
MYD: 102767014(TCF7L2)
MMYO: 118669739(TCF7L2)
MLF: 102428683(TCF7L2)
MDT: 132214342(TCF7L2)
PKL: 118719486(TCF7L2)
EFUS: 103288569(TCF7L2)
MNA: 107536455(TCF7L2)
DRO: 112300313(TCF7L2)
SHON: 118999410(TCF7L2)
AJM: 119040094(TCF7L2)
PDIC: 114496676(TCF7L2)
PHAS: 123828741(TCF7L2)
MMF: 118632022(TCF7L2)
PPAM: 129077183(TCF7L2)
HAI: 109384898(TCF7L2)
RFQ: 117035906(TCF7L2)
PALE: 102880370(TCF7L2)
PGIG: 120609085(TCF7L2)
PVP: 105291480(TCF7L2)
RAY: 107511705(TCF7L2)
MJV: 108408173(TCF7L2)
TOD: 119234547(TCF7L2)
SARA: 101546297(TCF7L2)
SETR: 125994905(TCF7L2)
LAV: 100656106(TCF7L2)
TMU: 101345532
ETF: 101657493(TCF7L2)
DNM: 101433286(TCF7L2)
MDO: 100021451(TCF7L2)
GAS: 123238173(TCF7L2)
SHR: 100922675(TCF7L2)
AFZ: 127551589
PCW: 110209517(TCF7L2)
TVP: 118828293(TCF7L2)
OAA: 100080633(TCF7L2)
GGA: 395508(TCF7L2)
PCOC: 116231615(TCF7L2)
MGP: 100545943
CJO: 107316122(TCF7L2)
TPAI: 128077851(TCF7L2)
LMUT: 125693546(TCF7L2)
NMEL: 110399432(TCF7L2)
APLA: 101790790(TCF7L2)
ACYG: 106031894(TCF7L2)
CATA: 118248729(TCF7L2)
AFUL: 116491447(TCF7L2)
TGU: 100229459(TCF7L2)
LSR: 110468252(TCF7L2)
SCAN: 103814128(TCF7L2)
PMOA: 120501961(TCF7L2)
OTC: 121341849(TCF7L2)
PRUF: 121350212(TCF7L2)
GFR: 102035103(TCF7L2)
FAB: 101808150(TCF7L2)
OMA: 130254705(TCF7L2)
PHI: 102110960(TCF7L2)
PMAJ: 107206579(TCF7L2)
CCAE: 111930957(TCF7L2)
CCW: 104695213(TCF7L2)
CBRC: 103616275(TCF7L2)
ETL: 114057387(TCF7L2)
ZAB: 102075283(TCF7L2)
ZLE: 135449944(TCF7L2)
ACHL: 103800973(TCF7L2)
SVG: 106850869(TCF7L2)
MMEA: 130581829(TCF7L2)
HRT: 120755667(TCF7L2)
SATI: 136364028(TCF7L2)
FPG: 101911463(TCF7L2)
FCH: 102053252(TCF7L2)
CCRI: 104158774
NNT: 104411918(TCF7L2)
SHAB: 115607965(TCF7L2)
ACUN: 113481635(TCF7L2)
TALA: 104368758(TCF7L2)
ACHC: 115348196(TCF7L2)
HALD: 104324218(TCF7L2)
HLE: 104830209(TCF7L2)
AGEN: 126043148
GCL: 127017519
CSTI: 104553138(TCF7L2)
LDI: 104346347(TCF7L2)
MNB: 103774896
DPUB: 104307193(TCF7L2)
EGZ: 104130428(TCF7L2)
NNI: 104022375(TCF7L2)
PCRI: 104033644(TCF7L2)
PCAO: 104051703(TCF7L2)
PADL: 103918670(TCF7L2)
AFOR: 103897740(TCF7L2)
FGA: 104083847(TCF7L2)
GSTE: 104263863
CLV: 102092542(TCF7L2)
MUI: 104548075(TCF7L2)
PGUU: 104464988
PLET: 104620802(TCF7L2)
EHS: 104510766
CMAC: 104478637(TCF7L2)
CUCA: 104067818(TCF7L2)
TEO: 104384501(TCF7L2)
BREG: 104643624(TCF7L2)
OHA: 104329504(TCF7L2)
ACAR: 104527872(TCF7L2)
CPEA: 104397916(TCF7L2)
CVF: 104283459(TCF7L2)
RTD: 128911762(TCF7L2)
AAM: 106483723(TCF7L2)
AROW: 112967920(TCF7L2)
NPD: 112957063(TCF7L2)
TGT: 104570256
DNE: 112993664(TCF7L2)
SCAM: 104140131
ASN: 102373887(TCF7L2)
AMJ: 102558653(TCF7L2)
CPOO: 109324083(TCF7L2)
GGN: 109287622(TCF7L2)
PSS: 102459521(TCF7L2)
CMY: 102935138(TCF7L2)
CCAY: 125639965(TCF7L2)
DCC: 119858498(TCF7L2)
CPIC: 101938831(TCF7L2)
TST: 117879792(TCF7L2)
CABI: 116832677(TCF7L2)
MRV: 120409598(TCF7L2)
ACS: 100561311(tcf7l2) 100563899
ASAO: 132770959(TCF7L2)
PVT: 110071969(TCF7L2)
SUND: 121924798(TCF7L2)
PBI: 103067231(TCF7L2)
PMUR: 107286251(TCF7L2)
CTIG: 120312245(TCF7L2)
TSR: 106550184(TCF7L2)
PGUT: 117678715(TCF7L2)
APRI: 131200547(TCF7L2)
PTEX: 113439111(TCF7L2)
NSS: 113413891(TCF7L2)
VKO: 123027730(TCF7L2)
PMUA: 114597477(TCF7L2)
PRAF: 128414229(TCF7L2)
ZVI: 118093455(TCF7L2)
HCG: 128350353(TCF7L2)
GJA: 107121002(TCF7L2)
STOW: 125437427(TCF7L2)
EMC: 129331736(TCF7L2)
XLA: 108697306 399164(tcf7l2.L)
XTR: 100101719(tcf7l2)
NPR: 108793512(TCF7L2)
RTEM: 120946834(TCF7L2)
BBUF: 121005422(TCF7L2)
BGAR: 122939052(TCF7L2)
MUO: 115469932(TCF7L2)
GSH: 117358752(TCF7L2)
DRE: 30510(tcf7l2)
PTET: 122351900 122355452(tcf7l2)
LROH: 127174150(tcf7l2)
OMC: 131550611(tcf7l2)
PPRM: 120474612(tcf7l2)
RKG: 130102768(tcf7l2)
MAMB: 125255599(tcf7l2)
CIDE: 127523576
CERY: 137007969(tcf7l2)
TROS: 130568894(tcf7l2)
TDW: 130438678(tcf7l2)
MANU: 129420463(tcf7l2)
IPU: 108274114
IFU: 128617569(tcf7l2)
PHYP: 113527302(tcf7l2)
SMEO: 124388632(tcf7l2)
TFD: 113638911(tcf7l2)
TVC: 132837872(tcf7l2)
TRN: 134321330(tcf7l2)
AMEX: 103031257(tcf7l2)
CMAO: 118809394(tcf7l2)
EEE: 113577640
CHAR: 105912592(tcf7l2)
TRU: 101067664(tcf7l2) 115250775
TFS: 130525331(tcf7l2)
LCO: 104932553(tcf7l2)
NCC: 104943463(tcf7l2)
TBEN: 117473593(tcf7l2)
CGOB: 115024930(tcf7l2)
GACU: 117543165(tcf7l2)
EMAC: 134870639(tcf7l2)
ELY: 117247028(tcf7l2)
EFO: 125880423(tcf7l2)
PLEP: 121958519(tcf7l2)
SLUC: 116061043(tcf7l2)
ECRA: 117936627(tcf7l2)
ESP: 116671026(tcf7l2)
PFLV: 114547666(tcf7l2)
GAT: 120819326(tcf7l2)
PPUG: 119213174(tcf7l2)
AFB: 129091849(tcf7l2)
CLUM: 117748491(tcf7l2)
PSWI: 130203272(tcf7l2)
MSAM: 119911965 119915700(tcf7l2)
SCHU: 122867452(tcf7l2)
CUD: 121528169(tcf7l2)
ALAT: 119009368(tcf7l2)
MZE: 101472434 101473558(tcf7l2)
OLA: 101169492(tcf7l2)
OML: 112154020(tcf7l2)
CSAI: 133418942(tcf7l2)
XMA: 102216716(tcf7l2)
XCO: 114151877(tcf7l2)
XHE: 116726851(tcf7l2)
PRET: 103473336 103481429(tcf7l2)
PFOR: 103142270(tcf7l2)
PLAI: 106949585
PMEI: 106920911(tcf7l2)
GAF: 122822874(tcf7l2)
PPRL: 129367839(tcf7l2)
CVG: 107090000(tcf7l2)
CTUL: 119774953(tcf7l2)
GMU: 124874826(tcf7l2)
NFU: 107387573(tcf7l2)
KMR: 108248252(tcf7l2)
ALIM: 106534544(tcf7l2)
NWH: 119424011(tcf7l2)
AOCE: 111579048(tcf7l2)
MCEP: 125022588(tcf7l2)
CSEM: 103381486(tcf7l2) 103385014
POV: 109627028(tcf7l2)
SSEN: 122759724(tcf7l2)
HHIP: 117753439(tcf7l2)
HSP: 118100785(tcf7l2)
PPLT: 128426520(tcf7l2)
SMAU: 118287728(tcf7l2)
LCF: 108901696
SDU: 111219725(tcf7l2)
SLAL: 111657117(tcf7l2)
XGL: 120794076(tcf7l2)
HCQ: 109513392(tcf7l2)
SSCV: 125991191
SBIA: 133495832(tcf7l2)
PEE: 133417553(tcf7l2)
PTAO: 133468900(tcf7l2)
BPEC: 110154410(tcf7l2)
MALB: 109962891(tcf7l2)
BSPL: 114846309(tcf7l2)
SJO: 128381904(tcf7l2)
OGO: 124039973 124048226(tcf7l2)
ELS: 105007703(tcf7l2)
SFM: 108932732 108940446(tcf7l2)
PKI: 111858155(tcf7l2)
AANG: 118220560(tcf7l2)
LOC: 102691677(tcf7l2)
PSEX: 120543224(tcf7l2)
LCM: 102346208(TCF7L2)
CMK: 103186546(tcf7l2)
RTP: 109926936(tcf7l2)
CPLA: 122561195(tcf7l2)
HOC: 132826295(tcf7l2)
LERI: 129704026(tcf7l2)
BFO: 118412533
BBEL: 109485396
CIN: 778773(tcf/lef)
SPU: 373203(Tcf/Lef)
LPIC: 129281687
APLC: 110984316
ARUN: 117306352
SKO: 100303556(tcf7l)
DME: Dmel_CG34403(pan)
DER: 6555877
DSI: Dsimw501_GD17850(Dsim_pan)
DSR: 110185475
DPO: 4811795
DPE: 6602541
DMN: 108164406
DWI: 6650061
DGR: 6570275
DAZ: 108617901
DHE: 111597895
DVI: 6636240
BOD: 106619378
TDA: 119684323
SCAC: 106082602
LCQ: 111687000
AGA: 133393042
ASTE: 118503338
AMOU: 128309466
AALI: 118462721
CNS: 116340013
BCOO: 119079471
AME: 726671
ALAB: 122717456
ADR: 102673651
BIM: 100745788
BTER: 100643645
BAFF: 126914329
BPYO: 122566945
BPAS: 132909728
FVI: 122527574
CCAL: 108623756
OBB: 114877554
OLG: 117607798
MGEN: 117223795
NMEA: 116427844
CGIG: 122404573
SOC: 105198489
MPHA: 105837174
AEC: 105151104
ACEP: 105619854
PBAR: 105424403
VEM: 105566494
HST: 105186992
DQU: 106742176
CFO: 105253941
LHU: 105675787
PGC: 109859232
OBO: 105281955
PCF: 106793924
VPS: 122627622
VCRB: 124422033
VVE: 124956742
NVI: 100120687
CSOL: 105360929
TPRE: 106659629
LHT: 122508891
LBD: 127289465
MDL: 103575344
CGLO: 123270387
FAS: 105268008
DAM: 107039091
AGIF: 122855368
VCAN: 122408223
CCIN: 107269034
DSM: 124413574
NPT: 124214633
NFB: 124177834
NLO: 107217103
NVG: 124299490
AROA: 105693237
TCA: 641465(Pan)
DPA: 109535398
SOY: 115883697
AGRG: 126741731
ATD: 109595558
CSET: 123323004
AGB: 108911640
LDC: 111509897
DVV: 114346985
NVL: 108564096
PPYR: 116175025
OTU: 111424736
BMOR: 101742450
BMAN: 114239539
MSEX: 115453597
BANY: 112058326
MJU: 123877387
NIQ: 126777880
VCD: 124540396
MCIX: 123666493
PMAC: 106719867
PPOT: 106111393
PXU: 106123142
PRAP: 110998995
PBX: 123714889
PNAP: 125057040
ZCE: 119837715
CCRC: 123703406
LSIN: 126970087
AAGE: 121736446
HAW: 110372629(pan)
HZE: 124642598
TNL: 113497924
SLIU: 111362072
OFU: 114365195
ATRA: 106137143
GMW: 113519401
PXY: 105381194
PGW: 126377867
LGLY: 125237359
CCRN: 123298057
API: 100161896
AGS: 114118917
RMD: 113550243
ACOO: 126837862
DVT: 126902986
BTAB: 109030753
DCI: 103521547
CLEC: 106664004
HHAL: 106686555(pan)
NLU: 111047051
HVI: 124359738
FOC: 113213663
TPAL: 117646745
ZNE: 110830984
CSEC: 111867222
BROR: 134533112
FCD: 110843907
DMK: 116929407
DPZ: 124310988
PVM: 113807509
PJA: 122263035
PCHN: 125026380
PMOO: 119580119
HAME: 121861552
PCLA: 123753598
CQD: 128694276
PTRU: 123515241
ESN: 126995658
MNZ: 135198615
HAZT: 108681978
EAF: 111718027
ISC: 8024587
DSV: 119437031
RSAN: 119393871
RMP: 119161120
VJA: 111267083
DPTE: 113799178
LPOL: 106461635
CEL: CELE_W10C8.2(pop-1)
TSP: Tsp_02818
PVUL: 126810828
PCAN: 112561450
BGT: 106050505
GAE: 121379435
HRF: 124151751
HRJ: 124284145
CRG: 105329818
CANU: 128168168
CVN: 111118586
OED: 125668449
MYI: 110453906
PMAX: 117329520
MCAF: 127708677
MMER: 123563751
RPHI: 132714295
DPOL: 127865925
MAEA: 128225096
OBI: 106876393
OSN: 115213272
LJP: 135461658
LAK: 106155607
LLON: 135489670
NVE: 5503766
ADF: 107340855
AMIL: 114964939
PDAM: 113677974
SPIS: 111346760
DGT: 114528487
XEN: 124459201
HMG: 100199257
AQU: 100641322(Tcf)
 » show all
Reference
  Authors
Prokunina-Olsson L, Welch C, Hansson O, Adhikari N, Scott LJ, Usher N, Tong M, Sprau A, Swift A, Bonnycastle LL, Erdos MR, He Z, Saxena R, Harmon B, Kotova O, Hoffman EP, Altshuler D, Groop L, Boehnke M, Collins FS, Hall JL
  Title
Tissue-specific alternative splicing of TCF7L2.
  Journal
Hum Mol Genet 18:3795-804 (2009)
DOI:10.1093/hmg/ddp321
  Sequence
[hsa:6934]
Reference
PMID:9065401
  Authors
Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H
  Title
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
  Journal
Science 275:1784-7 (1997)
DOI:10.1126/science.275.5307.1784
  Sequence
[hsa:6934]

KEGG   ORTHOLOGY: K04490
Entry
K04490                      KO                                     
Symbol
TCF7L1
Name
transcription factor 7-like 1
Pathway
map04310  Wnt signaling pathway
map04390  Hippo signaling pathway
map04520  Adherens junction
map04916  Melanogenesis
map04934  Cushing syndrome
map04936  Alcoholic liver disease
map05132  Salmonella infection
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05213  Endometrial cancer
map05215  Prostate cancer
map05216  Thyroid cancer
map05217  Basal cell carcinoma
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04490  TCF7L1; transcription factor 7-like 1
   04390 Hippo signaling pathway
    K04490  TCF7L1; transcription factor 7-like 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04490  TCF7L1; transcription factor 7-like 1
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04490  TCF7L1; transcription factor 7-like 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04490  TCF7L1; transcription factor 7-like 1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05225 Hepatocellular carcinoma
    K04490  TCF7L1; transcription factor 7-like 1
   05226 Gastric cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05216 Thyroid cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05221 Acute myeloid leukemia
    K04490  TCF7L1; transcription factor 7-like 1
   05217 Basal cell carcinoma
    K04490  TCF7L1; transcription factor 7-like 1
   05215 Prostate cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05213 Endometrial cancer
    K04490  TCF7L1; transcription factor 7-like 1
   05224 Breast cancer
    K04490  TCF7L1; transcription factor 7-like 1
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04490  TCF7L1; transcription factor 7-like 1
   05165 Human papillomavirus infection
    K04490  TCF7L1; transcription factor 7-like 1
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04490  TCF7L1; transcription factor 7-like 1
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04490  TCF7L1; transcription factor 7-like 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04490  TCF7L1; transcription factor 7-like 1
   04934 Cushing syndrome
    K04490  TCF7L1; transcription factor 7-like 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04490  TCF7L1; transcription factor 7-like 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K04490  TCF7L1; transcription factor 7-like 1
Genes
HSA: 83439(TCF7L1)
PTR: 744526(TCF7L1)
PPS: 100968002(TCF7L1)
GGO: 101151621(TCF7L1)
PON: 100436197(TCF7L1)
PPYG: 129030261(TCF7L1)
NLE: 100601518(TCF7L1)
HMH: 116483590(TCF7L1)
SSYN: 129461823(TCF7L1)
MCC: 694560(TCF7L1)
MCF: 102125513(TCF7L1)
MTHB: 126933391
MNI: 105465371(TCF7L1)
CSAB: 103219950(TCF7L1)
CATY: 105587638(TCF7L1)
PANU: 101017547(TCF7L1)
TGE: 112604528(TCF7L1)
MLEU: 105528862(TCF7L1)
RRO: 104659731(TCF7L1)
RBB: 108542809(TCF7L1)
TFN: 117062119(TCF7L1)
PTEH: 111551134(TCF7L1)
CANG: 105527514(TCF7L1)
CJC: 100403963(TCF7L1)
SBQ: 101033762(TCF7L1)
CIMI: 108295686(TCF7L1)
ANAN: 105707914(TCF7L1)
CSYR: 103266761
MMUR: 105876584(TCF7L1)
LCAT: 123637116(TCF7L1)
PCOQ: 105810284(TCF7L1)
OGA: 100940553(TCF7L1)
MMU: 21415(Tcf7l1)
MCAL: 110296038(Tcf7l1)
MPAH: 110315696(Tcf7l1)
RNO: 312451(Tcf7l1)
MCOC: 116099088(Tcf7l1)
ANU: 117715247(Tcf7l1)
MUN: 110541202(Tcf7l1)
CGE: 100753225(Tcf7l1)
MAUA: 101839395(Tcf7l1) 121142589
PROB: 127235531(Tcf7l1)
PLEU: 114681591(Tcf7l1)
MORG: 121437942(Tcf7l1)
MFOT: 126493279
AAMP: 119807723(Tcf7l1)
NGI: 103739783(Tcf7l1)
HGL: 101699909(Tcf7l1)
CPOC: 100731379(Tcf7l1)
CCAN: 109686184(Tcf7l1)
DORD: 106000204(Tcf7l1)
DSP: 122116902(Tcf7l1)
PLOP: 125356229(Tcf7l1)
NCAR: 124963199
MMMA: 107159692(Tcf7l1)
OCU: 100340471
OPI: 101522406(TCF7L1)
TUP: 102481394(TCF7L1)
GVR: 103585949(TCF7L1)
CFA: 612070(TCF7L1)
CLUD: 112664304(TCF7L1)
VVP: 112916685(TCF7L1)
VLG: 121490511(TCF7L1)
NPO: 129510910(TCF7L1)
AML: 100480690(TCF7L1)
UMR: 103671448(TCF7L1)
UAH: 113243231(TCF7L1)
UAR: 123799645(TCF7L1)
ELK: 111148131
LLV: 125108462
MPUF: 101670990(TCF7L1)
MNP: 132021404(TCF7L1)
MLK: 131840380(TCF7L1)
NVS: 122915045(TCF7L1)
ORO: 101382778(TCF7L1)
EJU: 114223462(TCF7L1)
ZCA: 113938298(TCF7L1)
MLX: 118007920(TCF7L1)
NSU: 110587588(TCF7L1)
LWW: 102731685(TCF7L1)
FCA: 101089850(TCF7L1)
PYU: 121019121(TCF7L1)
PCOO: 112869689(TCF7L1)
PBG: 122497097(TCF7L1)
PVIV: 125162247(TCF7L1)
LRUF: 124503502
PTG: 102958078(TCF7L1)
PPAD: 109263707(TCF7L1)
PUC: 125937396
AJU: 106978197
HHV: 120220478(TCF7L1)
BTA: 515303(TCF7L1)
BOM: 102281039(TCF7L1)
BIU: 109565564(TCF7L1)
BBUB: 102410081(TCF7L1)
BBIS: 105004594(TCF7L1)
CHX: 102187776(TCF7L1)
OAS: 100913162(TCF7L1)
BTAX: 128056483(TCF7L1)
ODA: 120851515(TCF7L1)
CCAD: 122441729(TCF7L1)
MBEZ: 129538967(TCF7L1)
SSC: 100523899(TCF7L1)
CFR: 102516787(TCF7L1)
CBAI: 105072093(TCF7L1)
CDK: 105104146(TCF7L1)
VPC: 102525926(TCF7L1)
BACU: 103010166(TCF7L1)
BMUS: 118905868(TCF7L1)
LVE: 103069353(TCF7L1)
OOR: 101287223(TCF7L1)
DLE: 111165393(TCF7L1)
PCAD: 102974053(TCF7L1)
PSIU: 116764402(TCF7L1)
NASI: 112399043(TCF7L1)
ECB: 100067427(TCF7L1)
EPZ: 103548276(TCF7L1)
EAI: 106838609(TCF7L1)
MYB: 102240393(TCF7L1)
MYD: 102768915(TCF7L1)
MMYO: 118668800(TCF7L1)
MLF: 102417756(TCF7L1)
MDT: 132213149(TCF7L1)
PKL: 118717604(TCF7L1)
EFUS: 103299070(TCF7L1)
MNA: 107528616(TCF7L1)
DRO: 112302951(TCF7L1)
SHON: 118982463(TCF7L1) 118989528
AJM: 119059869(TCF7L1)
PDIC: 114499663(TCF7L1)
PHAS: 123811980(TCF7L1)
MMF: 118630569(TCF7L1)
PPAM: 129073949(TCF7L1)
HAI: 109371340(TCF7L1)
RFQ: 117033407(TCF7L1)
PALE: 102886093(TCF7L1)
PGIG: 120594603(TCF7L1)
PVP: 105298541(TCF7L1)
RAY: 107506285(TCF7L1)
MJV: 108405898(TCF7L1)
TOD: 119259123(TCF7L1)
SARA: 101550691(TCF7L1)
SETR: 126024487(TCF7L1)
TMU: 101341696
ETF: 101655177(TCF7L1)
DNM: 101417902(TCF7L1)
MDO: 100030368(TCF7L1)
GAS: 123233138(TCF7L1)
SHR: 100922609(TCF7L1)
AFZ: 127547432
PCW: 110196343(TCF7L1)
TVP: 118844387(TCF7L1)
OAA: 114817948(TCF7L1)
GGA: 395230(TCF7L1)
PCOC: 116231327(TCF7L1)
MGP: 104917108(TCF7L1)
CJO: 107323707(TCF7L1)
TPAI: 128090167(TCF7L1)
LMUT: 125685234(TCF7L1)
NMEL: 110387133(TCF7L1)
APLA: 101801135(TCF7L1)
ACYG: 106048886(TCF7L1)
CATA: 118260930(TCF7L1)
AFUL: 116499387(TCF7L1)
TGU: 115498209(TCF7L1)
LSR: 110478270(TCF7L1)
PMOA: 120505008(TCF7L1)
OTC: 121346667(TCF7L1)
PRUF: 121359809(TCF7L1)
GFR: 102039905(TCF7L1)
FAB: 101817952(TCF7L1)
OMA: 130261854(TCF7L1)
PHI: 102105833(TCF7L1)
PMAJ: 107213891(TCF7L1)
CCAE: 111938914(TCF7L1)
CCW: 104683181(TCF7L1)
CBRC: 103620244(TCF7L1)
ETL: 114070472(TCF7L1)
ZLE: 135456937(TCF7L1)
SVG: 106862411(TCF7L1)
MMEA: 130586305(TCF7L1)
HRT: 120764102(TCF7L1)
SATI: 136372618(TCF7L1)
FPG: 101922879(TCF7L1)
FCH: 102051021(TCF7L1)
CCRI: 104165649
SHAB: 115618453(TCF7L1)
TALA: 104362330(TCF7L1)
ACHC: 115349900(TCF7L1)
HLE: 104828923(TCF7L1)
AGEN: 126051625
GCL: 127025235
NNI: 104022615(TCF7L1)
AFOR: 103904221(TCF7L1)
CLV: 102084814(TCF7L1)
CUCA: 104067006(TCF7L1)
CPEA: 104392687(TCF7L1)
CVF: 104285063(TCF7L1)
RTD: 128919648(TCF7L1)
AAM: 106497459
AROW: 112971101(TCF7L1)
DNE: 112994866
ASN: 102382172(TCF7L1)
AMJ: 102559656(TCF7L1)
CPOO: 109324635(TCF7L1)
GGN: 109286704(TCF7L1)
PSS: 102456229(TCF7L1)
CMY: 102947844(TCF7L1)
CCAY: 125626470(TCF7L1)
DCC: 119848739(TCF7L1)
CPIC: 101943923(TCF7L1)
TST: 117872874(TCF7L1)
CABI: 116820735(TCF7L1)
MRV: 120397584(TCF7L1)
ACS: 100553130(tcf7l1)
ASAO: 132782760(TCF7L1)
PVT: 110084320(TCF7L1)
SUND: 121934613(TCF7L1)
PBI: 103066724(TCF7L1)
PMUR: 107286235(TCF7L1)
CTIG: 120313945(TCF7L1)
TSR: 106539368(TCF7L1)
PGUT: 117677059(TCF7L1)
APRI: 131203795(TCF7L1)
PTEX: 113447733(TCF7L1)
NSS: 113414485(TCF7L1)
VKO: 123027052(TCF7L1)
PMUA: 114585748(TCF7L1)
PRAF: 128402557(TCF7L1)
ZVI: 118097303(TCF7L1)
HCG: 128333530(TCF7L1)
GJA: 107117396(TCF7L1)
STOW: 125441754(TCF7L1)
EMC: 129342060(TCF7L1)
XLA: 394281(tcf7l1.S) 397863(tcf7l1.L)
XTR: 448107(tcf7l1)
NPR: 108792469
RTEM: 120933071(TCF7L1)
BBUF: 120986167(TCF7L1)
BGAR: 122929474(TCF7L1)
MUO: 115469279(TCF7L1)
GSH: 117362505(TCF7L1)
DRE: 30523(tcf7l1a) 30556(tcf7l1b)
PTET: 122350851(tcf7l1b) 122353201(tcf7l1a) 122358150
LROH: 127169871(tcf7l1b) 127172457(tcf7l1a)
OMC: 131545540(tcf7l1b) 131548395(tcf7l1a)
PPRM: 120474207(tcf7l1a) 120481307(tcf7l1b)
RKG: 130078054(tcf7l1a) 130082133(tcf7l1b)
MAMB: 125262345(tcf7l1a) 125280430(tcf7l1b)
CERY: 137027367(tcf7l1b) 137029462(tcf7l1a)
TROS: 130546223(tcf7l1a) 130568298(tcf7l1b)
TDW: 130407032(tcf7l1b) 130411805(tcf7l1a)
MANU: 129414006(tcf7l1b) 129446566(tcf7l1a)
IPU: 108265410(tcf7l1b)
IFU: 128607348(tcf7l1b)
PHYP: 113546045
SMEO: 124399623(tcf7l1b)
TFD: 113645099(tcf7l1b)
TVC: 132853353(tcf7l1b)
TRN: 134318428(tcf7l1b)
AMEX: 103022374(tcf7l1b)
CMAO: 118813135(tcf7l1b) 118824685(tcf7l1a)
CHAR: 105902771(tcf7l1b) 105912913(tcf7l1a)
TFS: 130516798(tcf7l1a) 130525287(tcf7l1b)
NCC: 104946533(tcf7l1)
TBEN: 117482633 117496881(tcf7l1b)
PGEO: 117452970(tcf7l1b)
GACU: 117556347 117561075(tcf7l1b)
EMAC: 134868341 134874085(tcf7l1b)
EFO: 125890368(tcf7l1b) 125905690
PLEP: 121938910 121944425(tcf7l1b)
SLUC: 116041786 116053887(tcf7l1b)
PPUG: 119224565(tcf7l1b) 119226883
AFB: 129100781(tcf7l1b) 129102375
CLUM: 117736417(tcf7l1b) 117740101
PSWI: 130197066(tcf7l1b) 130205718(tcf7l1a)
SCHU: 122865509 122876664(tcf7l1b)
ALAT: 119019317(tcf7l1b) 119030554(tcf7l1a)
MZE: 101466461 101481605(tcf7l1)
OLA: 100820729(tcf7l1) 111948314
OML: 112148818(tcf7l1b) 112162929
CSAI: 133450325(tcf7l1b)
GAF: 122828060(tcf7l1b) 122847224
PPRL: 129371953(tcf7l1b) 129379828
CTUL: 119783953(tcf7l1b)
GMU: 124872815 124878390(tcf7l1b)
NFU: 107393717(tcf7l1) 107395259
KMR: 108236527(tcf7l1b) 108242566
ALIM: 106513792 106520143(tcf7l1)
MCEP: 124996986 125012430(tcf7l1b)
SSEN: 122758446 122769535(tcf7l1b)
HHIP: 117767600(tcf7l1b) 117771319(tcf7l1a)
HSP: 118114860(tcf7l1b) 118126041(tcf7l1a)
PPLT: 128425127(tcf7l1a) 128437962(tcf7l1b)
SMAU: 118284957 118314250(tcf7l1b)
XGL: 120805718(tcf7l1b) 120806258
SSCV: 125993929
SBIA: 133491088 133499396(tcf7l1b)
PEE: 133399727(tcf7l1b) 133413646
PTAO: 133475547(tcf7l1b) 133489903
MALB: 109954978
BSPL: 114861532(tcf7l1b) 114866425
SJO: 128364144(tcf7l1b) 128380140
SFM: 108923598 108929514(tcf7l1)
PKI: 111837756 111857498(tcf7l1)
AANG: 118206870(tcf7l1b)
LOC: 102692120(tcf7l1)
PSEX: 120538925(tcf7l1a)
LCM: 102364488(TCF7L1)
RTP: 109923795
CPLA: 122542996
HOC: 132837044
LERI: 129713291
 » show all
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056
Reference
PMID:1741298
  Authors
Castrop J, van Norren K, Clevers H
  Title
A gene family of HMG-box transcription factors with homology to TCF-1.
  Journal
Nucleic Acids Res 20:611 (1992)
DOI:10.1093/nar/20.3.611
  Sequence
[hsa:83439]

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