KEGG   ORTHOLOGY: K02812
Entry
K02812                      KO                                     

Name
sorF
Definition
sorbose PTS system EIIA component [EC:2.7.1.206]
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko02060  Phosphotransferase system (PTS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K02812  sorF; sorbose PTS system EIIA component
 09130 Environmental Information Processing
  09131 Membrane transport
   02060 Phosphotransferase system (PTS)
    K02812  sorF; sorbose PTS system EIIA component
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K02812  sorF; sorbose PTS system EIIA component
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.206  protein-Npi-phosphohistidine---L-sorbose phosphotransferase
     K02812  sorF; sorbose PTS system EIIA component
Transporters [BR:ko02000]
 Phosphotransferase system (PTS)
  Enzyme II
   Sorbose-specific II component
    K02812  sorF; sorbose PTS system EIIA component
Other DBs
RN: R04076
COG: COG2893
GO: 0008982
TC: 4.A.6.1.3
Genes
ECE: Z5617
ECS: ECs5002
ECF: ECH74115_5497
ETW: ECSP_5095
ELX: CDCO157_4685
EOI: ECO111_4838
EOJ: ECO26_5131
ECOO: ECRM13514_5148
ECOH: ECRM13516_4885
ECG: E2348C_4334
EOK: G2583_4844(sorF)
ECP: ECP_4237
ECOS: EC958_4474
EOC: CE10_4708
ECC: c4985
ELO: EC042_4388(sorF)
ESE: ECSF_3876
ELC: i14_4574
ELD: i02_4574
ELF: LF82_636
ECOI: ECOPMV1_04399(manX_7)
ECOJ: P423_22305
EFE: EFER_4081
SFL: SF4092(sorF)
SFX: S3638(sorF)
SFV: SFV_4097(sorF)
SFE: SFxv_4462
SFN: SFy_5870
SFS: SFyv_5937
SFT: NCTC1_04448(manX_4)
SSN: SSON_4197(sorF)
SBO: SBO_4047(sorF)
KPN: KPN_04406(manX)
KPJ: N559_4895
KPNU: LI86_25225
KPNK: BN49_5027(sorF)
KVA: Kvar_4840
KPE: KPK_5268(sorF)
KOX: KOX_08115
KOE: A225_0287
CAMA: F384_22145
RTG: NCTC13098_06890(manX_11)
REE: electrica_04781(manX_4)
EBF: D782_4247
YEN: YE0814(sorF)
YEY: Y11_22381
YEW: CH47_2673
YET: CH48_2518
YEE: YE5303_25211(sorF)
YFR: AW19_14
YIN: CH53_867
YKR: CH54_1648
LCB: LCABL_04250(sorA)
LRL: LC705_00408(sorA)
CPAS: Clopa_1339
BPRL: CL2_07380
 » show all
Reference
  Authors
Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G
  Title
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
  Journal
J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000
  Sequence

KEGG   ORTHOLOGY: K02813
Entry
K02813                      KO                                     

Name
sorB
Definition
sorbose PTS system EIIB component [EC:2.7.1.206]
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko02060  Phosphotransferase system (PTS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K02813  sorB; sorbose PTS system EIIB component
 09130 Environmental Information Processing
  09131 Membrane transport
   02060 Phosphotransferase system (PTS)
    K02813  sorB; sorbose PTS system EIIB component
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K02813  sorB; sorbose PTS system EIIB component
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.206  protein-Npi-phosphohistidine---L-sorbose phosphotransferase
     K02813  sorB; sorbose PTS system EIIB component
Transporters [BR:ko02000]
 Phosphotransferase system (PTS)
  Enzyme II
   Sorbose-specific II component
    K02813  sorB; sorbose PTS system EIIB component
Other DBs
RN: R04076
COG: COG3444
GO: 0008982
TC: 4.A.6.1.3
Genes
ECE: Z5616
ECS: ECs5001
ETW: ECSP_5094
ELX: CDCO157_4684
EOI: ECO111_4837
EOJ: ECO26_5130
ECOO: ECRM13514_5147
ECOH: ECRM13516_4884
ECG: E2348C_4333
EOK: G2583_4843(sorB)
ECP: ECP_4236
ECOS: EC958_4473
EOC: CE10_4707(sorB)
ECC: c4984
ELO: EC042_4387(sorB)
ESE: ECSF_3875
ELC: i14_4573
ELD: i02_4573
ELF: LF82_635
ECOI: ECOPMV1_04398(sorB)
ECOJ: P423_22300
EFE: EFER_4080
EAL: EAKF1_ch1895(manX)
SFL: SF4091(sorB)
SFX: S3639(sorB)
SFV: SFV_4096(sorB)
SFE: SFxv_4461
SFN: SFy_5869
SFS: SFyv_5936
SFT: NCTC1_04447(sorB)
SBO: SBO_4046(sorB)
KPN: KPN_04405(manX)
KPT: VK055_3069(manX2)
KPR: KPR_0387(sorA)
KPJ: N559_4896
KPNU: LI86_25230
KPNK: BN49_5028(sorB)
KVA: Kvar_4841
KPE: KPK_5269(sorB)
KOX: KOX_08110
KOE: A225_0286
CAMA: F384_22140
RTG: NCTC13098_06892(sorB_2)
REE: electrica_04782(sorB)
EBF: D782_4248
YEN: YE0813(sorB)
YEY: Y11_22391
YEW: CH47_2674(sorB)
YET: CH48_2517(sorB)
YEE: YE5303_25221(sorB)
YFR: AW19_13(sorB)
YIN: CH53_868(sorB)
YKR: CH54_1649
DVM: DvMF_0422
STK: STP_1527
LCS: LCBD_0429
LCE: LC2W_0424
LCW: BN194_04340(sorB)
LCB: LCABL_04260(sorB)
LRL: LC705_00409(sorB)
LRA: LRHK_422(sorB)
CBK: CLL_A3359
CBEI: LF65_05130
CPAS: Clopa_1340
CPAT: CLPA_c28990(sorB)
CPAE: CPAST_c28990(sorB)
BPRL: CL2_07370
STH: STH1939
APR: Apre_0157
 » show all
Reference
  Authors
Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G
  Title
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
  Journal
J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000
  Sequence

KEGG   ORTHOLOGY: K02814
Entry
K02814                      KO                                     

Name
sorA
Definition
sorbose PTS system EIIC component
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko02060  Phosphotransferase system (PTS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K02814  sorA; sorbose PTS system EIIC component
 09130 Environmental Information Processing
  09131 Membrane transport
   02060 Phosphotransferase system (PTS)
    K02814  sorA; sorbose PTS system EIIC component
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K02814  sorA; sorbose PTS system EIIC component
Transporters [BR:ko02000]
 Phosphotransferase system (PTS)
  Enzyme II
   Sorbose-specific II component
    K02814  sorA; sorbose PTS system EIIC component
Other DBs
RN: R04076
COG: COG3715
GO: 0008982
TC: 4.A.6.1.3
Genes
ECE: Z5615
ECS: ECs5000
ECF: ECH74115_5495
ETW: ECSP_5093
ELX: CDCO157_4683
EOI: ECO111_4836
EOJ: ECO26_5129
ECOO: ECRM13514_5146
ECOH: ECRM13516_4883
ECG: E2348C_4332
EOK: G2583_4842(sorA)
ECP: ECP_4235
ECOS: EC958_4472
ECV: APECO1_2451(sorA)
EOC: CE10_4706
ECC: c4983
ELO: EC042_4386(sorA)
ESE: ECSF_3874
ELC: i14_4572
ELD: i02_4572
ELF: LF82_634
ECOI: ECOPMV1_04397(manY_2)
ECOJ: P423_22295
EFE: EFER_4079
SFL: SF4090(sorA)
SFX: S3640(sorA)
SFV: SFV_4095(sorA)
SFE: SFxv_4460
SFN: SFy_5868
SFS: SFyv_5935
SFT: NCTC1_04446(manY_2)
SSN: SSON_4195(sorA)
SBO: SBO_4045(sorA)
SDY: SDY_4315
KPN: KPN_04404(manY)
KPT: VK055_3070(manY2)
KPR: KPR_0386(sorA)
KPJ: N559_4897
KPNU: LI86_25235
KPNK: BN49_5029(sorA)
KVA: Kvar_4842
KPE: KPK_5270(sorA)
KOX: KOX_08105
KOE: A225_0285
CAMA: F384_22135
RTG: NCTC13098_06893(manY_3)
REE: electrica_04783(manY_2)
EBF: D782_4249
YEN: YE0812(sorA)
YEY: Y11_22401
YEW: CH47_2675
YET: CH48_2516
YEE: YE5303_25231(sorA)
YFR: AW19_12
YIN: CH53_869
YKR: CH54_1650
STK: STP_1526
LCS: LCBD_0430
LCE: LC2W_0425
LCW: BN194_04350(sorA_2)
LCB: LCABL_04270(sorC)
LRL: LC705_00410(sorC)
LRA: LRHK_423
CPAS: Clopa_1341
CPAT: CLPA_c28980(sorA1)
CPAE: CPAST_c28980(sorA1)
BPRL: CL2_07360
 » show all
Reference
  Authors
Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G
  Title
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
  Journal
J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000
  Sequence

KEGG   ORTHOLOGY: K02815
Entry
K02815                      KO                                     

Name
sorM
Definition
sorbose PTS system EIID component
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko02060  Phosphotransferase system (PTS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K02815  sorM; sorbose PTS system EIID component
 09130 Environmental Information Processing
  09131 Membrane transport
   02060 Phosphotransferase system (PTS)
    K02815  sorM; sorbose PTS system EIID component
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K02815  sorM; sorbose PTS system EIID component
Transporters [BR:ko02000]
 Phosphotransferase system (PTS)
  Enzyme II
   Sorbose-specific II component
    K02815  sorM; sorbose PTS system EIID component
Other DBs
RN: R04076
COG: COG3716
GO: 0008982
TC: 4.A.6.1.3
Genes
ECE: Z5614
ECF: ECH74115_5494
ETW: ECSP_5092
ELX: CDCO157_4682A
EOI: ECO111_4835
ECOO: ECRM13514_5145
ECOH: ECRM13516_4882
ECG: E2348C_4331
EOK: G2583_4841(sorM)
ELR: ECO55CA74_23160
ECP: ECP_4234
ECOS: EC958_4471
EOC: CE10_4705
ECC: c4982
ELO: EC042_4385(sorM)
ESE: ECSF_3873
ELC: i14_4571
ELD: i02_4571
ELF: LF82_633
ECOI: ECOPMV1_04396(manZ_5)
ECOJ: P423_22290
EFE: EFER_4078
SFL: SF4089(sorM)
SFX: S3641(sorM)
SFV: SFV_4094(sorM)
SFE: SFxv_4459
SFN: SFy_5867
SFS: SFyv_5934
SFT: NCTC1_04445(sorM)
SSN: SSON_4194(sorM)
SBO: SBO_4044(sorM)
KPN: KPN_04403(manZ)
KPT: VK055_3071(manZ2)
KPR: KPR_0385(sorM)
KPJ: N559_4898
KPNU: LI86_25240
KPNK: BN49_5030(sorM)
KVA: Kvar_4843
KPE: KPK_5271(sorM)
KOX: KOX_08100
KOE: A225_0284
CAMA: F384_22130
RTG: NCTC13098_06895(manZ_7)
REE: electrica_04784(manZ_4)
EBF: D782_4250
YEN: YE0811(sorM)
YEY: Y11_22411
YEW: CH47_2676
YET: CH48_2515
YEE: YE5303_25241(sorM)
YFR: AW19_11
YIN: CH53_870
YKR: CH54_1651
STK: STP_1525
LCS: LCBD_0431(manZ)
LCE: LC2W_0426(manZ)
LCW: BN194_04360(sorM)
LCB: LCABL_04280(sorD)
LRL: LC705_00411(sorD)
LRA: LRHK_424
CPAS: Clopa_1342
CPAT: CLPA_c28970(sorM)
CPAE: CPAST_c28970(sorM)
BPRL: CL2_07350
 » show all
Reference
  Authors
Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G
  Title
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
  Journal
J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000
  Sequence

KEGG   ENZYME: 2.7.1.206
Entry
EC 2.7.1.206                Enzyme                                 

Name
protein-Npi-phosphohistidine---L-sorbose phosphotransferase;
sorABFM (gene names);
L-sorbose PTS permease;
EIISor;
Enzyme IISor
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
protein-Npi-phospho-L-histidine:L-sorbose Npi-phosphotransferase
Reaction(IUBMB)
[protein]-Npi-phospho-L-histidine + L-sorbose[side 1] = [protein]-L-histidine + L-sorbose 1-phosphate[side 2] [RN:R04076]
Reaction(KEGG)
R04076
Substrate
[protein]-Npi-phospho-L-histidine [CPD:C04261];
L-sorbose[side 1] [CPD:C00247]
Product
[protein]-L-histidine [CPD:C00615];
L-sorbose 1-phosphate[side 2] [CPD:C02888]
Comment
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
History
EC 2.7.1.206 created 1972 as EC 2.7.1.69, part transferred 2016 to EC 2.7.1.206
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Orthology
K02812  sorbose PTS system EIIA component
K02813  sorbose PTS system EIIB component
Genes
ECE: Z5616 Z5617
ECS: ECs5001 ECs5002
ECF: ECH74115_5497
ETW: ECSP_5094 ECSP_5095
ELX: CDCO157_4684 CDCO157_4685
EOI: ECO111_4837 ECO111_4838
EOJ: ECO26_5130 ECO26_5131
ECOO: ECRM13514_5147 ECRM13514_5148
ECOH: ECRM13516_4884 ECRM13516_4885
ECG: E2348C_4333 E2348C_4334
EOK: G2583_4843(sorB) G2583_4844(sorF)
EOC: CE10_4707(sorB) CE10_4708
ECC: c4984 c4985
ELO: EC042_4387(sorB) EC042_4388(sorF)
ECOI: ECOPMV1_04398(sorB) ECOPMV1_04399(manX_7)
SFL: SF4091(sorB) SF4092(sorF)
SFX: S3638(sorF) S3639(sorB)
SFV: SFV_4096(sorB) SFV_4097(sorF)
SFT: NCTC1_04447(sorB) NCTC1_04448(manX_4)
SSN: SSON_4197(sorF)
SBO: SBO_4046(sorB) SBO_4047(sorF)
KPN: KPN_04405(manX) KPN_04406(manX)
KPT: VK055_3068 VK055_3069(manX2)
KPR: KPR_0387(sorA)
KPNK: BN49_5027(sorF) BN49_5028(sorB)
KPE: KPK_5268(sorF) KPK_5269(sorB)
RTG: NCTC13098_06890(manX_11) NCTC13098_06892(sorB_2)
REE: electrica_04781(manX_4) electrica_04782(sorB)
YEN: YE0813(sorB) YE0814(sorF)
YEW: CH47_2673 CH47_2674(sorB)
YET: CH48_2517(sorB) CH48_2518
YEE: YE5303_25211(sorF) YE5303_25221(sorB)
YFR: AW19_13(sorB) AW19_14
YIN: CH53_867 CH53_868(sorB)
DVM: DvMF_0422
STK: STP_1527
LCS: LCBD_0429
LCE: LC2W_0424
LCW: BN194_04340(sorB)
LCB: LCABL_04250(sorA) LCABL_04260(sorB)
LRL: LC705_00408(sorA) LC705_00409(sorB)
LRA: LRHK_422(sorB)
CBK: CLL_A3359
CBEI: LF65_05130
STH: STH1939
APR: Apre_0157
 » show all
Reference
1  [PMID:7700234]
  Authors
Wehmeier UF, Wohrl BM, Lengeler JW
  Title
Molecular analysis of the phosphoenolpyruvate-dependent L-sorbose: phosphotransferase system from Klebsiella pneumoniae and of its multidomain structure.
  Journal
Mol Gen Genet 246:610-8 (1995)
DOI:10.1007/bf00298968
  Sequence
Reference
2  [PMID:10613875]
  Authors
Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G
  Title
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
  Journal
J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.206
IUBMB Enzyme Nomenclature: 2.7.1.206
ExPASy - ENZYME nomenclature database: 2.7.1.206
BRENDA, the Enzyme Database: 2.7.1.206

KEGG   REACTION: R04076
Entry
R04076                      Reaction                               

Name
protein-N(pi)-phosphohistidine:L-sorbose 1-phosphotransferase
Definition
Protein N(pi)-phospho-L-histidine + L-Sorbose <=> Protein histidine + Sorbose 1-phosphate
Equation
Reaction class
RC01069  C00247_C02888
RC03206  C00615_C04261
Enzyme
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
Orthology
K02812  sorbose PTS system EIIA component [EC:2.7.1.206]
K02813  sorbose PTS system EIIB component [EC:2.7.1.206]
K02814  sorbose PTS system EIIC component
K02815  sorbose PTS system EIID component
Other DBs
RHEA: 49299

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