KEGG   ORTHOLOGY: K03094
Entry
K03094                      KO                                     
Symbol
SKP1, CBF3D
Name
S-phase kinase-associated protein 1
Pathway
map04110  Cell cycle
map04111  Cell cycle - yeast
map04114  Oocyte meiosis
map04120  Ubiquitin mediated proteolysis
map04141  Protein processing in endoplasmic reticulum
map04310  Wnt signaling pathway
map04341  Hedgehog signaling pathway - fly
map04350  TGF-beta signaling pathway
map04710  Circadian rhythm
map05131  Shigellosis
map05132  Salmonella infection
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04120 Ubiquitin mediated proteolysis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04341 Hedgehog signaling pathway - fly
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04350 TGF-beta signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04111 Cell cycle - yeast
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04114 Oocyte meiosis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   05131 Shigellosis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04121 Ubiquitin system
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   03036 Chromosome and associated proteins
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Membrane trafficking [BR:ko04131]
 Endosome - Lysosome transport
  Acidification regulators
   RAVE complex
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   Cul7 complex
    Adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.1)
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CBF3 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Other DBs
COG: COG5201
Genes
HSA: 6500(SKP1)
PTR: 462063(SKP1)
PPS: 100981953(SKP1) 100996208 106635345
GGO: 101148010 101150703(SKP1)
PON: 100174716(SKP1) 112135798
NLE: 100596865(SKP1)
MCC: 100423634(SKP1)
MCF: 102119803 102142637(SKP1) 123569073
MTHB: 126941022 126956019
CSAB: 103244544(SKP1)
CATY: 105599767(SKP1)
PANU: 101022453(SKP1)
TGE: 112626075(SKP1)
RRO: 104659810(SKP1) 104677263
PTEH: 111529166(SKP1)
CANG: 105508650 105518214(SKP1)
CJC: 100398187(SKP1)
SBQ: 101030146(SKP1)
CSYR: 103268314(SKP1) 103273074
MMUR: 105869977(SKP1)
LCAT: 123628677 123637776(SKP1)
PCOQ: 105816013(SKP1) 105826482
OGA: 100947924(SKP1)
MMU: 21402(Skp1)
MCAL: 110305852(Skp1)
MPAH: 110331774(Skp1)
RNO: 287280(Skp1)
MCOC: 116078246(Skp1)
MUN: 110549633(Skp1)
CGE: 100757677(Skp1)
PLEU: 114683050(Skp1) 114699340
MORG: 121456270(Skp1) 121460492
AAMP: 119812769(Skp1) 119820564
NGI: 103729775(Skp1)
HGL: 101704606(Skp1)
CPOC: 100135616(Skp1)
CCAN: 109689481(Skp1)
DORD: 105987275 105996787(Skp1)
DSP: 122112677 122115441(Skp1)
OCU: 100339463
OPI: 101526971(SKP1)
TUP: 102483646(SKP1)
CFA: 111090648 474682(SKP1)
VVP: 112917057(SKP1)
AML: 100463880(SKP1)
UMR: 103663817(SKP1)
UAH: 113261736(SKP1)
UAR: 123790350(SKP1)
ELK: 111141245
MPUF: 101682868
ORO: 101374307 101386391(SKP1)
EJU: 114209510(SKP1)
MLX: 118016639(SKP1)
NSU: 110579487 110591280(SKP1)
LWW: 102733259(SKP1) 102745112
FCA: 101099017(SKP1)
PYU: 121010703(SKP1)
PBG: 122483174 122487406(SKP1)
LRUF: 124515676
PTG: 102957702(SKP1)
PPAD: 109250862(SKP1) 109271783
AJU: 106984903(SKP1)
BTA: 615427(SKP1)
BOM: 102266347(SKP1)
BIU: 109562016(SKP1)
BBUB: 102408224(SKP1) 102410717
BBIS: 104991862(SKP1)
CHX: 102174738 108633185(SKP1)
OAS: 100240716(SKP1) 114108593(SKP1)
SSC: 100520183 110259483(SKP1)
CFR: 102519293(SKP1)
CBAI: 105082123(SKP1)
CDK: 105090262(SKP1)
VPC: 102537329(SKP1)
BACU: 103011520 103018727(SKP1)
LVE: 103074429(SKP1) 103090703
OOR: 101289355(SKP1)
DLE: 111182443(SKP1)
PSIU: 116752165(SKP1) 116762631
ECB: 100062946(SKP1)
EPZ: 103543154(SKP1)
EAI: 106834656(SKP1)
MYB: 102251595(SKP1) 102251629
MYD: 102756513(SKP1)
MLF: 102432509(SKP1)
MNA: 107525395(SKP1)
HAI: 109382554(SKP1)
DRO: 112318134(SKP1)
SHON: 118990085(SKP1)
AJM: 119037619(SKP1)
PDIC: 114508802 114509558(SKP1)
PHAS: 123813217(SKP1)
PALE: 102885538(SKP1)
PGIG: 120581290(SKP1)
PVP: 105293569(SKP1)
RAY: 107506799(SKP1)
MJV: 108406083(SKP1)
TOD: 119243470(SKP1)
SARA: 101558065(SKP1)
LAV: 100663845(SKP1)
TMU: 101350591
DNM: 101411899(SKP1) 101437683
MDO: 100014810(SKP1)
GAS: 123235711(SKP1) 123251960
SHR: 100927300(SKP1)
PCW: 110211724(SKP1)
OAA: 100082731(SKP1)
GGA: 416319(SKP1)
PCOC: 116232219(SKP1)
MGP: 100544772(SKP1)
CJO: 107320209(SKP1)
NMEL: 110405291(SKP1)
APLA: 101803413(SKP1)
ACYG: 106032826(SKP1)
AFUL: 116494750(SKP1)
TGU: 100225726(SKP1)
LSR: 110481076(SKP1)
SCAN: 103817252(SKP1)
PMOA: 120498602(SKP1)
OTC: 121332298(SKP1)
PRUF: 121361304(SKP1)
GFR: 102038546(SKP1)
FAB: 101813841(SKP1)
PHI: 102099878(SKP1)
PMAJ: 107210641(SKP1)
CCAE: 111935605(SKP1)
CCW: 104683717(SKP1)
CBRC: 103614681(SKP1)
ETL: 114063912(SKP1)
ZAB: 102062694(SKP1)
ACHL: 103807215(SKP1)
FPG: 101911889(SKP1)
FCH: 102046372(SKP1)
CLV: 102094112(SKP1)
EGZ: 104133458(SKP1)
NNI: 104012003(SKP1)
PLET: 104615468(SKP1)
PCRI: 104025807(SKP1)
PCAO: 104040359(SKP1)
ACUN: 113485113(SKP1)
TALA: 104356436(SKP1)
PADL: 103915789(SKP1)
AFOR: 103904438(SKP1)
ACHC: 115334091(SKP1)
HALD: 104324276(SKP1)
AGEN: 126051123
GCL: 127021889
CCRI: 104156375(SKP1)
CSTI: 104551623(SKP1)
EHS: 104509276(SKP1)
CMAC: 104487535(SKP1)
MUI: 104548352(SKP1)
FGA: 104071429(SKP1)
GSTE: 104259570(SKP1)
LDI: 104347433(SKP1)
MNB: 103776348(SKP1)
OHA: 104338055(SKP1)
NNT: 104410084(SKP1)
DPUB: 104309583(SKP1)
PGUU: 104459900(SKP1)
ACAR: 104530197(SKP1)
CPEA: 104386829(SKP1)
AVIT: 104269132(SKP1)
CVF: 104291610(SKP1)
CUCA: 104060678(SKP1)
TEO: 104382522(SKP1)
BRHI: 104502232(SKP1)
AAM: 106487187(SKP1)
AROW: 112964703(SKP1)
NPD: 112952406(SKP1)
TGT: 104572830(SKP1)
DNE: 112994062(SKP1)
SCAM: 104146927(SKP1)
ASN: 102382934(SKP1)
AMJ: 102576679(SKP1)
CPOO: 109310090(SKP1)
GGN: 109289962(SKP1)
PSS: 102446427(SKP1)
CMY: 102931925 102935126(SKP1)
CPIC: 101936963(SKP1)
TST: 117882271(SKP1)
CABI: 116826640(SKP1)
MRV: 120369650(SKP1)
ACS: 100568037(skp1)
PVT: 110079401(SKP1)
SUND: 121922749(SKP1)
PBI: 103066791(SKP1)
PMUR: 107294918(SKP1)
CTIG: 120305515(SKP1)
TSR: 106542624(SKP1)
PGUT: 117656074(SKP1)
VKO: 123035727(SKP1)
PMUA: 114591269(SKP1) 114604549
ZVI: 118080358(SKP1) 118081788
GJA: 107125984(SKP1)
STOW: 125428417(SKP1)
XLA: 108712619(skp1.S) 380538(skp1.L)
XTR: 549273(skp1)
NPR: 108792127(SKP1)
RTEM: 120932428(SKP1)
BBUF: 121009396(SKP1)
BGAR: 122928264(SKP1)
DRE: 393716(skp1)
SRX: 107728271 107742439(skp1)
SANH: 107661767(skp1) 107692975
SGH: 107603266(skp1)
CCAR: 109048021(skp1) 109067897
PPRM: 120473620(skp1)
MAMB: 125253090(skp1)
IPU: 100528639(skp1)
PHYP: 113535613(skp1)
SMEO: 124398234(skp1)
TFD: 113646584(skp1)
AMEX: 103045526(skp1)
EEE: 113578037(skp1)
TRU: 101068627(skp1)
LCO: 104924374(skp1)
NCC: 104957032(skp1)
CGOB: 115019388(skp1)
ELY: 117262658(skp1)
EFO: 125898884(skp1)
PLEP: 121952874(skp1)
SLUC: 116055913(skp1)
ECRA: 117956006(skp1)
ESP: 116700182(skp1)
PFLV: 114567245(skp1)
GAT: 120821564(skp1)
PPUG: 119215587(skp1)
MSAM: 119895680(skp1)
CUD: 121519296(skp1)
ALAT: 119031719(skp1)
MZE: 101469121(skp1)
ONL: 100697275(skp1)
OAU: 116315813(skp1)
OLA: 101173567(skp1)
OML: 112142354(skp1)
XMA: 102221489(skp1)
XCO: 114152468(skp1)
XHE: 116728112(skp1)
PRET: 103459979(skp1)
PFOR: 103155759(skp1)
PLAI: 106935269(skp1)
PMEI: 106916702(skp1)
GAF: 122844692(skp1)
CVG: 107085893(skp1)
CTUL: 119797962(skp1)
GMU: 124876349(skp1)
NFU: 107386838(skp1)
KMR: 108238075(skp1)
ALIM: 106524567(skp1)
NWH: 119420461(skp1)
AOCE: 111583951(skp1)
MCEP: 125020944(skp1)
CSEM: 103394863(skp1)
POV: 109635809(skp1)
SSEN: 122779520(skp1)
HHIP: 117774290(skp1)
HSP: 118121781(skp1)
LCF: 108893670
SDU: 111234629(skp1)
SLAL: 111645238 111659985(skp1)
XGL: 120803142(skp1)
HCQ: 109515642(skp1)
BPEC: 110153983(skp1)
MALB: 109966791(skp1)
BSPL: 114869350(skp1)
SASA: 100195936(skp1) 106567526(SKP1)
ELS: 105026694(skp1)
PKI: 111839552 111847937(skp1)
AANG: 118223049 118234955(skp1)
LOC: 102694012(skp1)
PSEX: 120542076(skp1)
LCM: 102350053(SKP1)
BFO: 118411438
BBEL: 109481387
CIN: 100181511
SCLV: 120347360
SPU: 594639
APLC: 110980531
AJC: 117123316
SKO: 100313722
DME: Dmel_CG11941(SkpC) Dmel_CG11942(SkpE) Dmel_CG12227(SkpF) Dmel_CG12700(SkpD) Dmel_CG15800(CG15800) Dmel_CG16983(SkpA) Dmel_CG43089(CG43089) Dmel_CG8881(SkpB)
DSI: Dsimw501_GD16521(Dsim_GD16521) Dsimw501_GD17469(Dsim_GD17469) Dsimw501_GD25016(Dsim_GD25016) Dsimw501_GD25046(Dsim_GD25046) Dsimw501_GD25859(Dsim_GD25859) Dsimw501_GD29572(Dsim_GD29572)
MDE: 101898001
SCAC: 106085712
LCQ: 111679592
LSQ: 119604124
HIS: 119657956
ACOZ: 120958433
AARA: 120903772
ASTE: 118511765
AAG: 5571571
AME: 409234
ACER: 108002799
ALAB: 122717837
BIM: 100743026
BBIF: 117212199
BVK: 117236933
BVAN: 117155765
BTER: 100651427
BPYO: 122577665
CCAL: 108624497
OBB: 114881063
MGEN: 117229450
NMEA: 116430201
CGIG: 122398002
SOC: 105195125
MPHA: 105833585
ACEP: 105626331
PBAR: 105427532
VEM: 105568886
HST: 105187367
DQU: 106749170
FEX: 115245977
LHU: 105672747
PGC: 109853127
OBO: 105280685
PCF: 106787535
PFUC: 122524126
VPS: 122637340
FAS: 105263292
DAM: 107045374
LHT: 122508466
CCIN: 107272618
TCA: 663380(skp1)
SOY: 115882056
AGB: 108914919
NVL: 108559854
APLN: 108738467
OTU: 111413867
BMOR: 733106
BMAN: 114248511
MSEX: 115445831
BANY: 112053520
NIQ: 126781639
PMAC: 106708696
PPOT: 106100421
PRAP: 110992864
PBX: 123714823
PNAP: 125061479
ZCE: 119833463
CCRC: 123692167
HAW: 110372361
HZE: 124632257
TNL: 113508299
SLIU: 111358634
OFU: 114365087
PXY: 105397971
DNX: 107161275
AGS: 114126975
RMD: 113561270
BTAB: 109042339
CLEC: 106666260
HHAL: 106683441
NLU: 111056797
FOC: 113213403
TPAL: 117643167
ZNE: 110835390
CSEC: 111870551
DMK: 116925125
DPZ: 124326098
PVM: 113812043
PCHN: 125043588
HAME: 121872928
PCLA: 123768217
PTRU: 123520596
HAZT: 108680953
EAF: 111702527
LSM: 121114720
PPOI: 119107560
VDE: 111249188
TUT: 107361622
DPTE: 113795476
DFR: 124492315
PTEP: 107441722
SDM: 118204149
CEL: CELE_C06A8.4(skr-17) CELE_C42D4.6(skr-16) CELE_C52D10.6(skr-12) CELE_C52D10.7(skr-9) CELE_C52D10.8(skr-13) CELE_C52D10.9(skr-8) CELE_F44G3.6(skr-3) CELE_F46A9.4(skr-2) CELE_F46A9.5(skr-1) CELE_F47H4.10(skr-5) CELE_F54D10.1(skr-15) CELE_F56B3.12(skr-18) CELE_K08H2.1(skr-21) CELE_R12H7.3(skr-19) CELE_R12H7.5(skr-20) CELE_Y105C5B.13(skr-10) CELE_Y37H2C.2(skr-6) CELE_Y47D7A.1(skr-7) CELE_Y47D7A.8(skr-14) CELE_Y60A3A.18(skr-4)
BMY: BM_BM6609(Bm6609) BM_BM6611(Bm6611)
PCAN: 112560103
BGT: 106074681
GAE: 121380418
HRF: 124143157
HRJ: 124283966
CRG: 105325178
MYI: 110444357
PMAX: 117335666
MMER: 123537153
OBI: 106875753
OSN: 115211812
LAK: 106181029
SHX: MS3_00004999(SKP1)
NVE: 5514721
EPA: 110242232
ATEN: 116297636
PDAM: 113678011
SPIS: 111347008
DGT: 114527624
XEN: 124433590
ATH: AT1G10230(SK18) AT1G20140(SK4) AT1G75950(SKP1) AT2G03160(SK19) AT2G03170(SK14) AT2G03190(SK16) AT2G20160(MEO) AT2G25700(SK3) AT3G21830(SK8) AT3G21840(SK7) AT3G21850(SK9) AT3G21860(SK10) AT3G25650(SK15) AT3G53060(SK6) AT3G60010(SK13) AT3G60020(SK5) AT4G34210(SK11) AT4G34470(SK12) AT5G42190
LJA: Lj0g3v0079709.1(Lj0g3v0079709.1) Lj0g3v0106769.1(Lj0g3v0106769.1) Lj0g3v0259179.1(Lj0g3v0259179.1) Lj0g3v0261809.1(Lj0g3v0261809.1) Lj0g3v0349889.1(Lj0g3v0349889.1) Lj2g3v1267140.1(Lj2g3v1267140.1) Lj2g3v1670950.1(Lj2g3v1670950.1) Lj4g3v2366270.2(Lj4g3v2366270.2) Lj5g3v0186670.1(Lj5g3v0186670.1) Lj5g3v0186680.1(Lj5g3v0186680.1) Lj5g3v2242520.1(Lj5g3v2242520.1) Lj5g3v2243530.1(Lj5g3v2243530.1)
DOSA: Os02t0101600-00(Os02g0101600) Os02t0225100-00(Os02g0225100) Os06t0113800-00(Os06g0113800) Os07t0409500-01(Os07g0409500) Os07t0624900-00(Os07g0624900) Os07t0625400-01(Os07g0625400) Os07t0625500-01(Os07g0625500) Os07t0625600-00(Os07g0625600) Os08t0375500-00(Os08g0375500) Os08t0375700-00(Os08g0375700) Os09t0272900-01(Os09g0272900) Os09t0273800-01(Os09g0273800) Os09t0274800-00(Os09g0274800) Os09t0275200-01(Os09g0275200) Os09t0412050-00(Os09g0412050) Os09t0539500-01(Os09g0539500) Os10t0438100-00(Os10g0438100) Os11t0456300-01(Os11g0456300)
MNG: MNEG_0264
SCE: YDR328C(SKP1)
SEUB: DI49_0508
ERC: Ecym_8162
KMX: KLMA_60103(SKP1)
NCS: NCAS_0F02970(NCAS0F02970)
NDI: NDAI_0C04420(NDAI0C04420)
TPF: TPHA_0D02190(TPHA0D02190)
TBL: TBLA_0H01860(TBLA0H01860)
TDL: TDEL_0E02570(TDEL0E02570)
KAF: KAFR_0D04400(KAFR0D04400)
KNG: KNAG_0C05390(KNAG0C05390)
CAL: CAALFM_C107410CA(SKP1)
NCR: NCU08991(scon-3)
NTE: NEUTE1DRAFT117111(NEUTE1DRAFT_117111)
MGR: MGG_04978
SSCK: SPSK_09816
TRE: TRIREDRAFT_73823(skp1)
MAW: MAC_03119
MAJ: MAA_05788
CMT: CCM_02669
BFU: BCIN_03g01890(Bcskp1)
MBE: MBM_03677
ANI: AN2302.2
ABE: ARB_06761
TVE: TRV_03348
PTE: PTT_18813
SPO: SPBC409.05(skp1)
CNE: CNA08080
CNB: CNBA7900
TASA: A1Q1_01005
ABP: AGABI1DRAFT111082(AGABI1DRAFT_111082)
ABV: AGABI2DRAFT190295(AGABI2DRAFT_190295)
SCM: SCHCO_02605535(SCHCODRAFT_02605535)
MGL: MGL_3474
MRT: MRET_2107
DDI: DDB_G0269230(fpaA) DDB_G0273251(fpaB-1) DDB_G0273615(fpaB-2)
DFA: DFA_07127(fpaA) DFA_12090
EHI: EHI_065310 EHI_066770(181.t00006) EHI_118670(62.t00027) EHI_134960(153.t00018) EHI_174130(116.t00012) EHI_174180(116.t00016)
TAN: TA03425
TPV: TP03_0225
CPV: cgd7_2500
PTI: PHATRDRAFT_17276(Skp1_1)
VG: 16512567(pdul_cds_894) 16607219(psal_cds_1160)
 » show all
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
DOI:10.1038/nrm1547
Reference
PMID:8706131
  Authors
Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW, Elledge SJ
  Title
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.
  Journal
Cell 86:263-74 (1996)
DOI:10.1016/S0092-8674(00)80098-7
  Sequence
[sce:YDR328C]

KEGG   ORTHOLOGY: K03868
Entry
K03868                      KO                                     
Symbol
RBX1, ROC1
Name
E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
Pathway
map03420  Nucleotide excision repair
map04066  HIF-1 signaling pathway
map04110  Cell cycle
map04111  Cell cycle - yeast
map04114  Oocyte meiosis
map04120  Ubiquitin mediated proteolysis
map04141  Protein processing in endoplasmic reticulum
map04310  Wnt signaling pathway
map04341  Hedgehog signaling pathway - fly
map04350  TGF-beta signaling pathway
map04710  Circadian rhythm
map05131  Shigellosis
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
map05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04120 Ubiquitin mediated proteolysis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09124 Replication and repair
   03420 Nucleotide excision repair
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04341 Hedgehog signaling pathway - fly
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04350 TGF-beta signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04066 HIF-1 signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04111 Cell cycle - yeast
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04114 Oocyte meiosis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   03400 DNA repair and recombination proteins
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.32  cullin-RING-type E3 NEDD8 transferase
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  UBL E3 ligases
   K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  Multi subunit Ring-finger type E3
   SCF complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul2 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul3 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul4 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul7 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul8 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul9 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
    TCR (transcription coupled repair) factors
     Cul4-CSA complex
      K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
Other DBs
COG: COG5194
GO: 0019788
Genes
HSA: 9978(RBX1)
PTR: 458860(RBX1)
PPS: 100970959 100981636(RBX1)
GGO: 101151577(RBX1)
PON: 100441665(RBX1)
NLE: 100596079(RBX1)
MCC: 710252(RBX1)
MCF: 102132483(RBX1)
CSAB: 103223367(RBX1)
CATY: 105572541(RBX1)
PANU: 101025661(RBX1)
TGE: 112633503(RBX1)
RRO: 104673455(RBX1)
RBB: 108528465(RBX1)
TFN: 117096433(RBX1)
PTEH: 111532697 111548968(RBX1)
CANG: 105527741(RBX1)
CJC: 100391523(RBX1)
SBQ: 101031903(RBX1)
CSYR: 103260489(RBX1)
MMUR: 105858549(RBX1)
LCAT: 123640318(RBX1)
PCOQ: 105805282(RBX1)
OGA: 100963359(RBX1)
MMU: 56438(Rbx1)
MCAL: 110310464(Rbx1)
MPAH: 110334961(Rbx1)
RNO: 300084(Rbx1)
MCOC: 116076358(Rbx1)
MUN: 110550435(Rbx1)
CGE: 100762556(Rbx1)
MAUA: 101838028(Rbx1)
PLEU: 114694298(Rbx1) 114707186
MORG: 121444018 121461000(Rbx1)
AAMP: 119823435(Rbx1)
NGI: 103743488(Rbx1)
HGL: 101712475(Rbx1)
CPOC: 100714763(Rbx1)
CCAN: 109686914(Rbx1)
DORD: 105992090(Rbx1)
DSP: 122123619(Rbx1)
NCAR: 124983356
OCU: 103352470
OPI: 101519048(RBX1)
TUP: 102468598(RBX1)
GVR: 103585666(RBX1)
CFA: 474494(RBX1)
CLUD: 112667276(RBX1)
VVP: 112934005(RBX1)
VLG: 121491679(RBX1)
UMR: 103674160(RBX1)
UAH: 113241739(RBX1)
UAR: 123780699(RBX1)
ELK: 111157501
LLV: 125106731
MPUF: 101687674(RBX1)
ORO: 101363104(RBX1)
EJU: 114218392(RBX1)
ZCA: 113911560 113921968(RBX1)
MLX: 117998640(RBX1)
NSU: 110577946(RBX1)
LWW: 102748318(RBX1)
FCA: 101087758(RBX1)
PYU: 121040293(RBX1)
PBG: 122472803(RBX1)
LRUF: 124501699
PTG: 102955881(RBX1)
PPAD: 109265611(RBX1)
AJU: 113602716(RBX1)
BTA: 518880(RBX1) 780968
BOM: 102272719(RBX1)
BIU: 109559850(RBX1)
BBUB: 102414522(RBX1)
BBIS: 104981171(RBX1)
CHX: 102187112(RBX1) 102188771
OAS: 101109871(RBX1)
ODA: 120857602(RBX1)
SSC: 110260638(RBX1)
CFR: 102515877(RBX1)
CBAI: 105073197(RBX1)
CDK: 105091911(RBX1)
VPC: 102535913(RBX1)
BACU: 102998295(RBX1)
LVE: 103090829(RBX1)
OOR: 101287254(RBX1) 101289349
DLE: 111186303(RBX1)
PCAD: 102983946(RBX1)
PSIU: 116749210 116760644(RBX1)
ECB: 100055581(RBX1)
EPZ: 103556120(RBX1)
EAI: 106842455(RBX1)
MYD: 102760790(RBX1)
MLF: 102431403(RBX1)
MNA: 107531277(RBX1)
PKL: 118730800(RBX1)
HAI: 109392275(RBX1)
DRO: 112321770(RBX1)
SHON: 119002280(RBX1)
AJM: 119060371(RBX1)
PDIC: 114513192(RBX1)
PHAS: 123816194(RBX1)
MMF: 118618357 118624414(RBX1)
RFQ: 117029081(RBX1)
PALE: 102893437(RBX1)
PGIG: 120602973(RBX1)
PVP: 105298053(RBX1)
RAY: 107519712(RBX1)
MJV: 108394317(RBX1)
TOD: 119247226(RBX1)
SARA: 101542238(RBX1) 101554111
LAV: 100657479(RBX1)
TMU: 101349359
ETF: 101646762(RBX1) 101662489
DNM: 101444027(RBX1)
MDO: 100013521(RBX1)
GAS: 123250747(RBX1)
SHR: 100918404(RBX1)
PCW: 110205825(RBX1)
OAA: 100076928(RBX1)
GGA: 418001(RBX1)
PCOC: 116233383(RBX1)
MGP: 100543550(RBX1)
CJO: 107312930(RBX1)
NMEL: 110392307(RBX1)
APLA: 101796040(RBX1)
ACYG: 106035919(RBX1)
AFUL: 116501779(RBX1)
TGU: 100190092(RBX1)
LSR: 110483089(RBX1)
SCAN: 103813288(RBX1)
PMOA: 120510088(RBX1)
OTC: 121342452(RBX1)
PRUF: 121361199(RBX1)
GFR: 102037823(RBX1)
FAB: 101806409(RBX1)
PHI: 102102832(RBX1)
PMAJ: 107204430(RBX1)
CCAE: 111934630(RBX1)
CCW: 104696532(RBX1)
CBRC: 103618243(RBX1)
ETL: 114058064(RBX1)
ZAB: 102069638(RBX1)
ACHL: 103803839
FPG: 101916874(RBX1)
FCH: 102049129(RBX1)
CLV: 102095842(RBX1)
ACUN: 113488055(RBX1)
TALA: 104364386(RBX1)
PADL: 103915729(RBX1)
AFOR: 103907880(RBX1)
ACHC: 115352685(RBX1)
HALD: 104318900(RBX1)
HLE: 104829039(RBX1)
AGEN: 126047828
GCL: 127022521
CSTI: 104549877(RBX1)
FGA: 104079903(RBX1)
OHA: 104329873(RBX1)
NNT: 104399424(RBX1)
ACAR: 104519277(RBX1)
CPEA: 104387596(RBX1)
CUCA: 104055502(RBX1)
AAM: 106488968(RBX1)
AROW: 112965730(RBX1)
NPD: 112946469(RBX1)
TGT: 104574103(RBX1)
DNE: 112984067(RBX1)
SCAM: 104137962(RBX1)
ASN: 102372162(RBX1)
AMJ: 102571619(RBX1)
CPOO: 109316717(RBX1)
GGN: 109295958(RBX1)
PSS: 102451113(RBX1)
CMY: 102943754(RBX1)
CPIC: 101936281(RBX1)
TST: 117880076(RBX1)
CABI: 116829058(RBX1)
ACS: 100566553(rbx1)
PVT: 110076073(RBX1)
SUND: 121932202(RBX1)
PBI: 103065423(RBX1)
PMUR: 107285413(RBX1)
CTIG: 120304681(RBX1)
TSR: 106537822(RBX1) 106553210
PGUT: 117655425(RBX1)
VKO: 123036074(RBX1)
PMUA: 114605459(RBX1)
ZVI: 118091458(RBX1)
GJA: 107117140(RBX1)
STOW: 125435698(RBX1)
XLA: 108714482(rbx1.L) 108715730(rbx1.S)
XTR: 100379935(rbx1)
NPR: 108788200(RBX1)
RTEM: 120945492(RBX1)
BBUF: 120979112(RBX1)
BGAR: 122943674(RBX1)
DRE: 449846(rbx1)
SANH: 107672143(rbx1) 107695112
SGH: 107580054 107602336(rbx1)
CCAR: 109076699(rbx1)
PPRM: 120462132(rbx1)
MAMB: 125273687(rbx1)
PHYP: 113524074(rbx1)
SMEO: 124381909(rbx1)
TFD: 113640136(rbx1)
AMEX: 107197156(rbx1)
EEE: 113583718(rbx1)
LCO: 104932083(rbx1)
NCC: 104945083(rbx1)
CGOB: 115012294(rbx1)
ELY: 117268068(rbx1)
EFO: 125879233(rbx1)
PLEP: 121956973(rbx1) 121966503
SLUC: 116065292(rbx1)
ECRA: 117958649(rbx1)
ESP: 116702801(rbx1)
PFLV: 114569772(rbx1)
GAT: 120827413(rbx1)
PPUG: 119220154(rbx1)
MSAM: 119884920(rbx1)
CUD: 121529177(rbx1)
ALAT: 119013730(rbx1)
MZE: 101480103(rbx1)
ONL: 100696705(rbx1)
OAU: 116327876(rbx1)
OLA: 101170590(rbx1)
OML: 112146889(rbx1)
XMA: 102233269(rbx1)
XCO: 114160562(rbx1)
XHE: 116736204(rbx1)
PRET: 103468459(rbx1)
PFOR: 103153424(rbx1)
PLAI: 106961597(rbx1)
PMEI: 106930562(rbx1)
GAF: 122822198(rbx1)
CVG: 107093096(rbx1)
CTUL: 119799435(rbx1)
NFU: 107376330(rbx1)
KMR: 108236172(rbx1)
ALIM: 106520678(rbx1)
NWH: 119422119(rbx1)
AOCE: 111570331(rbx1)
MCEP: 124998308(rbx1)
CSEM: 103393328(rbx1)
POV: 109643626(rbx1)
SSEN: 122785647(rbx1)
HHIP: 117766292(rbx1)
HSP: 118122773(rbx1)
LCF: 108877581
SDU: 111230345(rbx1)
SLAL: 111645594 111647571(rbx1)
XGL: 120783375(rbx1)
HCQ: 109514860(rbx1)
BPEC: 110162377(rbx1)
MALB: 109952664(rbx1)
BSPL: 114860326 114860329(rbx1)
SASA: 100136424(rbx1) 106601243(rbx1)
OMY: 100301858(rbx1) 110486413
ELS: 105025789(rbx1)
PKI: 111845210(rbx1) 111853244
AANG: 118216689(rbx1) 118218515
PSPA: 121306188(rbx1)
PSEX: 120536924(rbx1)
LCM: 102352187(RBX1)
CMK: 103189242(rbx1)
RTP: 109921792(rbx1)
BFO: 118419573
BBEL: 109487751
CIN: 100182516
SCLV: 120342351
APLC: 110984414
AJC: 117111407
DME: Dmel_CG16982(Roc1a) Dmel_CG16988(Roc1b)
DSI: Dsimw501_GD11014(Dsim_GD11014) Dsimw501_GD16520(Dsim_GD16520)
SCAC: 106096045
HIS: 119656903
ACOZ: 120947991
AARA: 120898375
ASTE: 118509359
AAG: 5565270
CPII: 120417029
CNS: 116347560
BCOO: 119080998
AME: 408691
ACER: 107996873
ALAB: 122718323
BIM: 100750218
BBIF: 117206781
BVK: 117236796
BVAN: 117155771
BTER: 100643234
BPYO: 122575860
CCAL: 108631453
OBB: 114871947
MGEN: 117217818
NMEA: 116430110
CGIG: 122398060
SOC: 105195164
MPHA: 105839647
AEC: 105148347
ACEP: 105626311
PBAR: 105432274
VEM: 105568857
HST: 105188519
DQU: 106740675
CFO: 105252239
FEX: 115233657
LHU: 105674184
PGC: 109852514
OBO: 105284276
PCF: 106787165
PFUC: 122515250
VPS: 122636059
NVI: 100115578
CSOL: 105361251
TPRE: 106652040
MDL: 103578781
CGLO: 123261074
FAS: 105267552
DAM: 107041044
AGIF: 122852012
CINS: 118068144
LHT: 122505034
CCIN: 107266769
TCA: 655935
DPA: 109536288
SOY: 115874647
CSET: 123309188
AGB: 108917391
LDC: 111512846
NVL: 108557707
APLN: 108733335
PPYR: 116168719
OTU: 111417661
BMOR: 692971
BMAN: 114248509
MSEX: 115445862
BANY: 112053517
NIQ: 126781640
PMAC: 106708735
PPOT: 106100422
PXU: 106123473
PRAP: 110992851
PBX: 123714871
PNAP: 125061084
ZCE: 119833226
CCRC: 123692168
HAW: 110372277
HZE: 124632258
TNL: 113508302
SLIU: 111358319
OFU: 114365077
PXY: 105397966
DNX: 107162314
BTAB: 109044484
CLEC: 106666282
HHAL: 106682125
NLU: 111058671
FOC: 113211873
TPAL: 117639298
ZNE: 110832453
CSEC: 111870542
FCD: 110848901
DMK: 116925355
PVM: 113818542
PJA: 122244209
PCHN: 125046917
HAME: 121862336
PCLA: 123756750
PTRU: 123509381
HAZT: 108678153
EAF: 111714026
LSM: 121123682
DSV: 119449384
RSAN: 119382413
RMP: 119178187
VDE: 111249014
VJA: 111266216
TUT: 107362230
DPTE: 113789362
DFR: 124497975
PTEP: 107454093
SDM: 118193171
CEL: CELE_ZK287.5(rbx-1)
CBR: CBG_19342(Cbr-rbx-1)
BMY: BM_BM14000(Bma-rbx-1)
PCAN: 112559116
GAE: 121375242
HRF: 124143675
HRJ: 124284529
CRG: 105317988
MYI: 110455961
PMAX: 117328726
MMER: 123557832
OBI: 106882699
OSN: 115218629
LAK: 106150763
NVE: 5509443
EPA: 110249442
ATEN: 116291507
ADF: 107349974
AMIL: 114969829
PDAM: 113677930
SPIS: 111341613
DGT: 114530307
XEN: 124445670
HMG: 100204043
AQU: 100636037
ATH: AT3G42830 AT5G20570(RBX1)
ALY: 9308017
CPAP: 110817690
TCC: 18588272
LJA: Lj0g3v0042719.1(Lj0g3v0042719.1) Lj0g3v0262469.1(Lj0g3v0262469.1) Lj3g3v1339080.1(Lj3g3v1339080.1)
ZJU: 107423885
MNT: 21410023
NNU: 104600540
DOSA: Os01t0106800-01(Os01g0106800) Os02t0708300-01(Os02g0708300)
PEQ: 110019661
MNG: MNEG_4176
APRO: F751_6626
OLU: OSTLU_119493(rbx1)
MIS: MICPUN_113936(RBX1)
SCE: YOL133W(HRT1)
SEUB: DI49_2274
ERC: Ecym_2029
KMX: KLMA_70161(HRT1)
NCS: NCAS_0C04480(NCAS0C04480)
NDI: NDAI_0G03860(NDAI0G03860)
TPF: TPHA_0P01470(TPHA0P01470)
TBL: TBLA_0B08710(TBLA0B08710)
TDL: TDEL_0A00470(TDEL0A00470)
KAF: KAFR_0C01780(KAFR0C01780)
KNG: KNAG_0A01280(KNAG0A01280)
PIC: PICST_37145(HRT1)
CAL: CAALFM_C302450WA(HRT1)
NTE: NEUTE1DRAFT116888(NEUTE1DRAFT_116888)
MGR: MGG_08844
SSCK: SPSK_02774
MAW: MAC_01896
MAJ: MAA_00593
CMT: CCM_05836
BFU: BCIN_03g07500(Bchrt1)
MBE: MBM_08230
ANI: AN8844.2
ANG: ANI_1_294154(An17g02100)
ALUC: AKAW2_70780S(RBX1)
ACHE: ACHE_11205A(RBX1)
APUU: APUU_70423A(RBX1)
ABE: ARB_07022
TVE: TRV_07648
PTE: PTT_16968
SPO: SPAC23H4.18c(rbx1)
CNE: CNB03140
CNB: CNBB2560
ABP: AGABI1DRAFT130185(AGABI1DRAFT_130185)
ABV: AGABI2DRAFT139777(AGABI2DRAFT_139777)
MORE: E1B28_013366(RBX1)
SCM: SCHCO_02628431(SCHCODRAFT_02628431)
MGL: MGL_0788
MRT: MRET_0028
DDI: DDB_G0287629(rbx1)
EHI: EHI_151630(2.t00108)
TAN: TA10565
TPV: TP04_0669
CPV: cgd8_930
SMIN: v1.2.005788.t1(symbB.v1.2.005788.t1)
PTI: PHATRDRAFT_39090(Rbx1)
NGD: NGA_0441600(RBX1)
SPAR: SPRG_11654
 » show all
Reference
  Authors
Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG Jr, Elledge SJ, Conaway RC, Harper JW, Conaway JW
  Title
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
  Journal
Science 284:657-61 (1999)
DOI:10.1126/science.284.5414.657
  Sequence
[sce:YOL133W]
Reference
  Authors
Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW
  Title
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
  Journal
Genes Dev 13:2928-33 (1999)
DOI:10.1101/gad.13.22.2928
  Sequence
[hsa:9978] [sce:YOL133W]
Reference
  Authors
Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y
  Title
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
  Journal
Mol Cell Biol 20:8185-97 (2000)
DOI:10.1128/mcb.20.21.8185-8197.2000

KEGG   ORTHOLOGY: K03347
Entry
K03347                      KO                                     
Symbol
CUL1, CDC53
Name
cullin 1
Pathway
map04110  Cell cycle
map04111  Cell cycle - yeast
map04114  Oocyte meiosis
map04120  Ubiquitin mediated proteolysis
map04141  Protein processing in endoplasmic reticulum
map04310  Wnt signaling pathway
map04340  Hedgehog signaling pathway
map04341  Hedgehog signaling pathway - fly
map04350  TGF-beta signaling pathway
map04710  Circadian rhythm
map05131  Shigellosis
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03347  CUL1, CDC53; cullin 1
   04120 Ubiquitin mediated proteolysis
    K03347  CUL1, CDC53; cullin 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03347  CUL1, CDC53; cullin 1
   04340 Hedgehog signaling pathway
    K03347  CUL1, CDC53; cullin 1
   04341 Hedgehog signaling pathway - fly
    K03347  CUL1, CDC53; cullin 1
   04350 TGF-beta signaling pathway
    K03347  CUL1, CDC53; cullin 1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03347  CUL1, CDC53; cullin 1
   04111 Cell cycle - yeast
    K03347  CUL1, CDC53; cullin 1
   04114 Oocyte meiosis
    K03347  CUL1, CDC53; cullin 1
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    K03347  CUL1, CDC53; cullin 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03347  CUL1, CDC53; cullin 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03347  CUL1, CDC53; cullin 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03347  CUL1, CDC53; cullin 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03347  CUL1, CDC53; cullin 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Cullin
     K03347  CUL1, CDC53; cullin 1
Other DBs
COG: COG5647
Genes
HSA: 8454(CUL1)
PTR: 463821(CUL1)
PPS: 100972042(CUL1)
GGO: 109025459(CUL1)
NLE: 100580180(CUL1)
MCC: 710581(CUL1)
MCF: 101867010(CUL1)
MTHB: 126951000
CSAB: 103227180(CUL1)
CATY: 105584691(CUL1)
PANU: 101000243(CUL1)
TGE: 112620234(CUL1)
RRO: 104667014(CUL1)
RBB: 108522304(CUL1)
TFN: 117073499(CUL1)
PTEH: 111551417(CUL1)
CANG: 105511282(CUL1)
CJC: 100395702(CUL1)
SBQ: 101051291(CUL1)
CSYR: 103259717(CUL1)
MMUR: 105873323(CUL1)
LCAT: 123647562(CUL1)
PCOQ: 105824617(CUL1)
OGA: 100962270(CUL1)
MMU: 26965(Cul1)
MCAL: 110296040(Cul1)
MPAH: 110316251(Cul1)
RNO: 362356(Cul1)
MCOC: 116098531(Cul1)
MUN: 110547501(Cul1)
CGE: 100757763(Cul1)
MAUA: 101824322(Cul1)
PLEU: 114698005(Cul1)
MORG: 121433638(Cul1)
MFOT: 126515064
AAMP: 119806685(Cul1)
NGI: 103731381(Cul1)
HGL: 101703786(Cul1)
CPOC: 100727053(Cul1)
CCAN: 109695511(Cul1)
DORD: 105989577(Cul1)
DSP: 122105888(Cul1)
OCU: 100345752
OPI: 101529995(CUL1)
TUP: 102497446(CUL1)
GVR: 103592393(CUL1)
CFA: 475512(CUL1)
CLUD: 112651078(CUL1)
VVP: 112934801(CUL1)
VLG: 121489188(CUL1)
AML: 100466596(CUL1)
UMR: 103668956(CUL1)
UAH: 113241451(CUL1)
UAR: 123788818(CUL1)
ELK: 111154336
LLV: 125080978
MPUF: 101684109(CUL1) 101687227
ORO: 101369645(CUL1)
EJU: 114211586(CUL1)
ZCA: 113910992(CUL1)
MLX: 118021218(CUL1)
NSU: 110582976(CUL1)
LWW: 102745690
FCA: 101087051(CUL1)
PYU: 121028153(CUL1)
PBG: 122488471(CUL1)
LRUF: 124524656
PTG: 102957061(CUL1)
PPAD: 109269217(CUL1)
AJU: 106981418(CUL1)
HHV: 120246394(CUL1)
BTA: 407228(CUL1)
BIU: 109557757(CUL1)
BBUB: 102400493(CUL1) 102400980
BBIS: 104991415(CUL1)
CHX: 102189276(CUL1)
OAS: 101106584(CUL1)
ODA: 120877870(CUL1) 120878126
CCAD: 122437764 122438828(CUL1)
SSC: 100524037(CUL1)
CFR: 102517054(CUL1)
CBAI: 105068877(CUL1)
CDK: 105085195(CUL1)
VPC: 102525911(CUL1)
BACU: 103011656(CUL1)
LVE: 103070988(CUL1)
OOR: 101280362(CUL1)
DLE: 111177194(CUL1)
PSIU: 116759055(CUL1) 116759317
ECB: 100051217(CUL1)
EPZ: 103553705(CUL1)
EAI: 106842121(CUL1)
MYB: 102245795(CUL1)
MYD: 102771406(CUL1)
MMYO: 118666292(CUL1) 118677220
MLF: 102421559(CUL1)
MNA: 107523767(CUL1)
PKL: 118714188(CUL1)
HAI: 109395450(CUL1)
DRO: 112308266(CUL1)
SHON: 118979473(CUL1)
AJM: 119051030(CUL1)
PDIC: 114508034(CUL1)
PHAS: 123815585(CUL1)
MMF: 118619799(CUL1)
RFQ: 117018094(CUL1)
PALE: 102887109(CUL1)
PGIG: 120601485(CUL1)
PVP: 105295712(CUL1)
RAY: 107500535(CUL1)
MJV: 108386656(CUL1)
TOD: 119248858(CUL1)
SARA: 101545316(CUL1)
LAV: 100664600(CUL1)
TMU: 101360163
ETF: 101648516(CUL1)
DNM: 101415205(CUL1)
MDO: 100013348(CUL1)
GAS: 123249675(CUL1)
SHR: 100926417(CUL1)
PCW: 110201672(CUL1)
OAA: 100073945(CUL1)
GGA: 420783(CUL1)
PCOC: 116228278(CUL1)
MGP: 100540218(CUL1)
CJO: 107309836(CUL1)
NMEL: 110390791(CUL1)
APLA: 101793264(CUL1)
ACYG: 106048734(CUL1)
AFUL: 116486424(CUL1)
TGU: 100223849(CUL1)
LSR: 110479185(CUL1)
SCAN: 103819366(CUL1)
PMOA: 120504992(CUL1)
OTC: 121346973(CUL1)
PRUF: 121352852(CUL1)
GFR: 102038503(CUL1)
FAB: 101810352(CUL1)
PHI: 102100590(CUL1)
PMAJ: 107200314(CUL1)
CCAE: 111923644(CUL1)
CCW: 104688924(CUL1)
CBRC: 103615760(CUL1)
ETL: 114063866(CUL1)
ZAB: 102065044(CUL1)
ACHL: 103804006
FPG: 101911159(CUL1)
FCH: 102056187(CUL1)
CLV: 102093584(CUL1)
EGZ: 104124772(CUL1)
NNI: 104015389(CUL1)
PLET: 104625738(CUL1)
PCRI: 104035750(CUL1)
PCAO: 104052171(CUL1)
ACUN: 113477562(CUL1)
TALA: 104355727(CUL1)
PADL: 103916089(CUL1)
AFOR: 103895376(CUL1)
ACHC: 115339346(CUL1)
HALD: 104323242(CUL1)
HLE: 104828374(CUL1)
AGEN: 126045386
GCL: 127012844
CCRI: 104168370
CSTI: 104562484(CUL1)
CMAC: 104484581(CUL1)
MUI: 104547417
FGA: 104083690(CUL1)
GSTE: 104254100(CUL1)
LDI: 104342578
MNB: 103776907(CUL1)
OHA: 104334078(CUL1)
NNT: 104402769(CUL1)
DPUB: 104298260(CUL1)
PGUU: 104467157(CUL1)
ACAR: 104525062(CUL1)
CPEA: 104392173(CUL1)
AVIT: 104278793(CUL1)
CVF: 104295307(CUL1)
CUCA: 104065930(CUL1)
TEO: 104370308(CUL1)
BRHI: 104495769(CUL1)
AAM: 106495275(CUL1)
AROW: 112970377(CUL1)
NPD: 112942705(CUL1)
TGT: 104567377(CUL1)
DNE: 112997514(CUL1)
SCAM: 104150319(CUL1)
ASN: 102371987(CUL1)
AMJ: 102562508(CUL1)
CPOO: 109313015(CUL1)
GGN: 109291896(CUL1)
PSS: 102452815(CUL1)
CMY: 102932876(CUL1)
CPIC: 101938030(CUL1)
TST: 117872629(CUL1)
CABI: 116825807(CUL1)
MRV: 120397820(CUL1)
ACS: 100563024(cul1)
PVT: 110088676(CUL1)
SUND: 121932531(CUL1)
PBI: 103051969(CUL1)
PMUR: 107288848
CTIG: 120316551(CUL1)
TSR: 106547022(CUL1)
PGUT: 117664970(CUL1)
VKO: 123017636(CUL1)
PMUA: 114607913(CUL1)
ZVI: 118077678(CUL1)
GJA: 107119625(CUL1)
STOW: 125440583(CUL1)
XLA: 734414(cul1.S) 734526(cul1.L)
XTR: 734121(cul1)
NPR: 108794363(CUL1)
RTEM: 120940358(CUL1)
BBUF: 121002808(CUL1)
BGAR: 122938030(CUL1)
DRE: 323883(cul1a) 406816(cul1b)
PPRM: 120475952(cul1b) 120482573(cul1a)
MAMB: 125250170(cul1a) 125258299(cul1b)
IPU: 108256454(cul1b) 108280768(cul1a)
SMEO: 124403259(cul1a) 124403783(cul1b)
TFD: 113655494(cul1a) 113660248(cul1b)
AMEX: 103026940(cul1) 111194478
EEE: 113584345
TRU: 101068951(cul1)
LCO: 104933878(cul1)
NCC: 104940785(cul1)
CGOB: 115006280(cul1)
ELY: 117264677
EFO: 125881497
PLEP: 121960512
SLUC: 116039988
ECRA: 117938296
ESP: 116679238(cul1)
PFLV: 114549315(cul1)
GAT: 120811508
PPUG: 119198294
MSAM: 119896622
CUD: 121527211
ALAT: 119009067
MZE: 101485891(cul1)
ONL: 100699353(cul1)
OAU: 116329343
OLA: 101155471(cul1)
OML: 112152486
XMA: 102238349(cul1)
XCO: 114136425(cul1)
XHE: 116712100(cul1)
PRET: 103457010(cul1)
PFOR: 103131052(cul1)
PLAI: 106961041(cul1)
PMEI: 106932872(cul1)
GAF: 122824392
CVG: 107097881(cul1)
CTUL: 119791678
GMU: 124858143
NFU: 107383137(cul1)
KMR: 108249552
ALIM: 106531655(cul1)
NWH: 119426609
AOCE: 111571338(cul1)
MCEP: 125024463
CSEM: 103377187(cul1)
POV: 109645364(cul1)
SSEN: 122768303
HHIP: 117753552
HSP: 118098323
LCF: 108885000
SDU: 111238316(cul1)
SLAL: 111647272(cul1)
XGL: 120789562
HCQ: 109530293(cul1)
BPEC: 110158319(cul1)
MALB: 109951060(cul1)
BSPL: 114852913
CCLU: 121535270(cul1a) 121549775(cul1b) 121580962
ELS: 105022041(cul1) 105024245
SFM: 108919683(cul1) 108935504
LOC: 102692217(cul1)
PSEX: 120529478(cul1b)
LCM: 102360768(CUL1)
CMK: 103187003(cul1b)
RTP: 109916300(cul1)
BFO: 118403913
BBEL: 109464828
SCLV: 120342615
SPU: 589630
APLC: 110975971
AJC: 117110772
DME: Dmel_CG11261(Cul6) Dmel_CG1877(Cul1)
DSI: Dsimw501_GD10516(Dsim_GD10516) Dsimw501_GD12683(Dsim_GD12683)
DPE: 6590465
DWI: 6640400
DGR: 6560496
DAZ: 108616909
DNV: 108654970
DHE: 111599944
DVI: 6635882
CCAT: 101458358
BOD: 106623040
RZE: 108379281
MDE: 101893739
SCAC: 106094257
LCQ: 111682503
LSQ: 119605495
HIS: 119659418
ACOZ: 120955217
AARA: 120899756
ASTE: 118513833
AAG: 5578149
AALB: 115258731
CINS: 118073676
SOY: 115874148
CSET: 123306750
AGB: 108904357
LDC: 111514642
APLN: 108739595
PPYR: 116161016
OTU: 111424274
PNAP: 125055159
TPAL: 117645753
DMK: 116936321
PVM: 113816603
LSM: 121115608
DSV: 119456052
RSAN: 119393633
RMP: 119172077
VDE: 111252943
VJA: 111273311
TUT: 107366218
DFR: 124496790
CEL: CELE_D2045.6(cul-1) CELE_K08E7.7(cul-6)
CBR: CBG_17038 CBG_17039 CBG_18382(Cbr-cul-1)
PCAN: 112557063
BGT: 106079300
GAE: 121385437
HRF: 124135855
HRJ: 124262695
CRG: 105325130
MYI: 110451924
PMAX: 117322387
MMER: 123561446
NVE: 5509071
ATEN: 116296640
AMIL: 114977368
DGT: 114517451
XEN: 124439837
ALY: 9310976
CRB: 17884026
BRP: 103836734
CPAP: 110821436
VRA: 106768610
VAR: 108346100
CCAJ: 109807764
LJA: Lj0g3v0209709.2(Lj0g3v0209709.2)
FVE: 101303474
CSV: 101216323
CMO: 103497868
MCHA: 111009631
CPEP: 111806899
VVI: 100233054(CUL1) 100261361
SLY: 101249757
SPEN: 107006861
SSTN: 125874677
CANN: 107842772
NTA: 107770609 107807954(cul1C)
NSY: 104229650
NTO: 104090935
NAU: 109223502
CCAV: 112529394
BVG: 104886440
SOE: 110791258
DOSA: Os01t0369000-01(Os01g0369000) Os01t0369200-01(Os01g0369200)
PHAI: 112885784
PDA: 103716049
EGU: 105045249
MUS: 103974412
DCT: 110116436
PEQ: 110037334
AOF: 109849771
ATR: 18422906
SMO: SELMODRAFT_158171(CUL1-2) SELMODRAFT_173394(CUL1-1)
APRO: F751_6385
SCE: YDL132W(CDC53)
SEUB: DI49_0940
ERC: Ecym_8046
KMX: KLMA_60494(CDC53)
NCS: NCAS_0A13810(NCAS0A13810)
NDI: NDAI_0A02230(NDAI0A02230)
TPF: TPHA_0P00850(TPHA0P00850)
TBL: TBLA_0A05930(TBLA0A05930)
TDL: TDEL_0H01480(TDEL0H01480)
KAF: KAFR_0B01150(KAFR0B01150)
KNG: KNAG_0C04070(KNAG0C04070)
PIC: PICST_29770(CDC53)
CAL: CAALFM_C301700WA(CDC53)
NCR: NCU05204(cul-1)
NTE: NEUTE1DRAFT80573(NEUTE1DRAFT_80573)
MGR: MGG_07145
SSCK: SPSK_07032
MAW: MAC_08080
MAJ: MAA_05122
CMT: CCM_04213
MBE: MBM_02956
ANI: AN1019.2
ANG: ANI_1_830074(An08g05870)
ABE: ARB_01462
TVE: TRV_05741
PTE: PTT_04953
SPO: SPAC17G6.12(cul1)
CNE: CNN01140
CNB: CNBN1130
TASA: A1Q1_03354
DDI: DDB_G0267384(culB) DDB_G0278991(culE) DDB_G0291972(culA)
DFA: DFA_09462(culA)
EHI: EHI_156450(100.t00027)
SMIN: v1.2.024830.t1(symbB.v1.2.024830.t1)
PTI: PHATRDRAFT_29317(CUL1_3)
SPAR: SPRG_01077
 » show all
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
DOI:10.1038/nrm1547
Reference
PMID:9499404
  Authors
Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M
  Title
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.
  Journal
Genes Dev 12:692-705 (1998)
DOI:10.1101/gad.12.5.692
  Sequence
[sce:YDL132W]
Reference
PMID:8681378
  Authors
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM
  Title
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
  Journal
Cell 85:829-39 (1996)
DOI:10.1016/S0092-8674(00)81267-2
  Sequence
[hsa:8454]

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