KEGG   ORTHOLOGY: K03096
Entry
K03096                      KO                                     
Symbol
FRAT2
Name
frequently rearranged in advanced T-cell lymphomas 2
Pathway
map04310  Wnt signaling pathway
map05010  Alzheimer disease
map05022  Pathways of neurodegeneration - multiple diseases
map05200  Pathways in cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
   05226 Gastric cancer
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
   05224 Breast cancer
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
   05022 Pathways of neurodegeneration - multiple diseases
    K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
Genes
HSA: 23401(FRAT2)
PTR: 466170(FRAT2)
PPS: 100980813(FRAT2)
GGO: 101145989 129524968(FRAT2)
PON: 100462141(FRAT2)
PPYG: 129006111(FRAT2)
NLE: 100584425(FRAT2)
HMH: 116456610(FRAT2)
SSYN: 129468268(FRAT2)
MCC: 705730(FRAT2)
MCF: 102118171(FRAT2)
MTHB: 126962094
MNI: 105478452(FRAT2) 105493979
CSAB: 103216336(FRAT2)
CATY: 105581786(FRAT2)
PANU: 101013482(FRAT2)
TGE: 112631579(FRAT2)
RRO: 104682818(FRAT2)
RBB: 108534423(FRAT2)
TFN: 117069095(FRAT2)
PTEH: 111534487(FRAT2)
CANG: 105518300(FRAT2)
CJC: 100407124(FRAT2)
CIMI: 108285512(FRAT2)
ANAN: 105718524 135273939(FRAT2)
MMUR: 105873009(FRAT2)
LCAT: 123650180(FRAT2)
PCOQ: 105818469(FRAT2)
OGA: 100967077(FRAT2)
MMU: 212398(Frat2)
MCAL: 110285818(Frat2)
MPAH: 110331957(Frat2)
RNO: 679110(Frat2)
MCOC: 116103836(Frat2)
ANU: 117698585(Frat2)
CGE: 113834828
MAUA: 101838800(Frat2)
PROB: 127233365(Frat2)
PLEU: 114706894
MORG: 121454641(Frat2)
MFOT: 126504586
AAMP: 119822724(Frat2)
NGI: 103733235(Frat2)
HGL: 101724720(Frat2)
CPOC: 101789016(Frat2)
CCAN: 109695293(Frat2)
DORD: 105986580(Frat2)
DSP: 122115797(Frat2)
PLOP: 125346206(Frat2)
NCAR: 124984951
MMMA: 107149939(Frat2)
OCU: 108178409
GVR: 103590898(FRAT2)
CFA: 106557930
CLUD: 112672133
VVP: 112909220(FRAT2)
VLG: 121476396
NPO: 129523327
AML: 117802815(FRAT2)
UMR: 121101237(FRAT2)
UAH: 113251778(FRAT2)
UAR: 123783968(FRAT2)
ELK: 111145112
LLV: 125085133
MPUF: 101672972
MLK: 131828592(FRAT2)
NVS: 122900976(FRAT2)
ORO: 101370444(FRAT2)
EJU: 114205206(FRAT2)
ZCA: 113913785(FRAT2)
FCA: 105261037(FRAT2)
PYU: 121037466(FRAT2)
PBG: 122493081(FRAT2)
PVIV: 125148448(FRAT2)
LRUF: 124507028
PPAD: 109261937 109272710(FRAT2)
PUC: 125932835
AJU: 128312599
HHV: 120230549
BTA: 539144(FRAT2)
BIU: 109553193(FRAT2)
BBUB: 102402275(FRAT2)
CHX: 108634037(FRAT2)
OAS: 101108269(FRAT2)
BTAX: 128067855(FRAT2)
ODA: 120873961(FRAT2)
CCAD: 122446366(FRAT2)
MBEZ: 129555495(FRAT2) 129559989
SSC: 110256599(FRAT2)
CFR: 116667093(FRAT2)
CDK: 116155842(FRAT2)
BACU: 103014787(FRAT2)
BMUS: 118883090(FRAT2)
LVE: 103072485(FRAT2)
OOR: 101282307(FRAT2)
DLE: 111172445(FRAT2)
PCAD: 102985227(FRAT2)
PSIU: 116741587(FRAT2)
ECB: 111773573(FRAT2)
EAI: 123278957(FRAT2)
MMYO: 118669907(FRAT2)
MDT: 132214199(FRAT2)
PKL: 118719349(FRAT2)
EFUS: 103288637(FRAT2)
MNA: 107542516(FRAT2)
SHON: 118990287(FRAT2)
AJM: 119044524
PDIC: 114497273(FRAT2)
PHAS: 123828798(FRAT2)
MMF: 118632277(FRAT2)
PPAM: 129077273(FRAT2)
HAI: 109379589(FRAT2)
RFQ: 117036217(FRAT2)
PGIG: 120609254(FRAT2)
PVP: 105301374(FRAT2)
RAY: 107520416(FRAT2)
MJV: 118971914 118971915(FRAT2)
TOD: 119233541(FRAT2)
SETR: 125994820
LAV: 100669183(FRAT2)
TMU: 101352330
ETF: 101654581(FRAT2)
DNM: 101434851
MDO: 100022170(FRAT2)
GAS: 123234297
SHR: 100930993
TVP: 118827857(FRAT2)
OAA: 114810222
GGA: 107052763
PCOC: 116227617
CJO: 107310401(FRAT2)
TPAI: 128091387
LMUT: 125690784
APLA: 113842553
ACYG: 125184162
CATA: 118247993
AFUL: 116485658
TGU: 115493953
LSR: 116183328
PMOA: 120500845
OTC: 121340142
OMA: 130250344
PHI: 102112277
PMAJ: 107216152
CCW: 120409696
ETL: 114060079
ZAB: 102074135
ZLE: 135443363
SVG: 106860692
MMEA: 130576026
HRT: 120760057
SATI: 136370260(FRAT2)
SHAB: 115616425
TALA: 122152656
ACHC: 115340833
AGEN: 126048241
GCL: 127013391
RTD: 128906310
CMY: 119565567(FRAT2)
CCAY: 125632678
DCC: 119851309(FRAT2)
CPIC: 101938552(FRAT2)
TST: 117873671(FRAT2)
CABI: 116829033
MRV: 120396554(FRAT2)
ASAO: 132774991
SUND: 121929540
PMUR: 107292745
CTIG: 120310348
TSR: 106556726
PGUT: 117668513
APRI: 131195804
PTEX: 113439903
NSS: 113428225
VKO: 123020579
PMUA: 114600415
PRAF: 128417232
ZVI: 118090471
HCG: 128324625
GJA: 107109260
STOW: 125439346
EMC: 129333876
XLA: 108719340 398043(frat1.S)
XTR: 100491326(frat1)
NPR: 108801074
RTEM: 120941346
BBUF: 121001495
BGAR: 122938250
MUO: 115479030
GSH: 117353685(FRAT2)
DRE: 30719(gbp)
SGH: 107600509
PTET: 122361118
LROH: 127179167(gbp)
OMC: 131521822(gbp)
PPRM: 120462321
RKG: 130089731(gbp)
MAMB: 125243756
CIDE: 127497319
CERY: 137026278(gbp)
TROS: 130557669(gbp)
TDW: 130433024(gbp)
MANU: 129448496(gbp)
IPU: 108270737(gbp)
IFU: 128613338(gbp)
PHYP: 113526912
SMEO: 124383769
TFD: 113644805(gbp)
TVC: 132845657(gbp)
TRN: 134310500(gbp)
AMEX: 103030979(gbp)
CMAO: 118800379
EEE: 113572206
CHAR: 105893987
TRU: 101073270(frat2)
TFS: 130533243(gbp)
LCO: 104935873
NCC: 104951239
TBEN: 117496453(gbp)
CGOB: 115021426
GACU: 117552636(gbp)
EMAC: 134862307(gbp)
ELY: 117266464(gbp)
EFO: 125893920
PLEP: 121946179
SLUC: 116064550
ECRA: 117945945(gbp)
PFLV: 114557309
GAT: 120810989
PPUG: 119198197
AFB: 129109041(gbp)
CLUM: 117745835(gbp)
PSWI: 130187979(gbp)
MSAM: 119896933
SCHU: 122881161
CUD: 121512980
ALAT: 119006042
MZE: 101479986
ONL: 100693301(frat2)
OAU: 116327134(gbp)
OLA: 111948976(frat2)
OML: 112136603(gbp)
CSAI: 133441206(gbp)
XMA: 111608053
XCO: 114141593
XHE: 116717770
PRET: 103477472
PMEI: 106911896
GAF: 122830892
PPRL: 129355831
CVG: 107095268
CTUL: 119780899
GMU: 124865542
NFU: 107379012
KMR: 108250609(gbp)
ALIM: 106536974
NWH: 119408196
MCEP: 125016900
CSEM: 103388054
POV: 109623591(frat2)
SSEN: 122774156
HHIP: 117776591(gbp)
HSP: 118114150
PPLT: 128449987(gbp)
SMAU: 118284695
LCF: 108884690
SDU: 111234107
SLAL: 111644684
XGL: 120784799
HCQ: 109521076
SSCV: 125975295
SBIA: 133501416(gbp)
PEE: 133402132(gbp)
PTAO: 133479228(gbp)
BPEC: 110157885
MALB: 109970068
BSPL: 114843661(gbp)
SJO: 128366709(gbp)
SASA: 101448021(gbp) 106605477(GBP)
OTW: 112222877(gbp) 112228893
OMY: 110486689(gbp) 110513818
ELS: 105019237(frat2)
SFM: 114912585
PKI: 111835808
AANG: 118228847(gbp)
LOC: 102694687(frat2)
PSEX: 120515703
LCM: 102367067(FRAT2)
CMK: 103174308
RTP: 109912828
CPLA: 122548985
HOC: 132815467(gbp)
BFO: 118417441
ACOZ: 120953188
AARA: 120898696
ASTE: 118509202
AFUN: 125766924
CPII: 120418153
CNS: 116348021
TCA: 107399299
SOY: 115882405
AGRG: 126749043
AGB: 108906260
APLN: 108737290
ZNE: 110832648
CSEC: 111875434
IEL: 124166849
PVM: 113819809
PJA: 122255058
PCHN: 125038184
PCLA: 123769543
CQD: 128702183
PTRU: 123519454
ESN: 127003479
HAZT: 108679457
EAF: 111696943
LSM: 121121736
TCF: 131884726
DSV: 119436190
RSAN: 119407294
RMP: 119177150
VDE: 111254466
VJA: 111262338
SDM: 118192309
GAE: 121389149
 » show all
Reference
  Authors
Saitoh T, Moriwaki J, Koike J, Takagi A, Miwa T, Shiokawa K, Katoh M
  Title
Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway.
  Journal
Biochem Biophys Res Commun 281:815-20 (2001)
DOI:10.1006/bbrc.2001.4421
  Sequence
[hsa:23401]

KEGG   ORTHOLOGY: K03069
Entry
K03069                      KO                                     
Symbol
FRAT1
Name
frequently rearranged in advanced T-cell lymphomas 1
Pathway
map04310  Wnt signaling pathway
map05010  Alzheimer disease
map05022  Pathways of neurodegeneration - multiple diseases
map05200  Pathways in cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
   05226 Gastric cancer
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
   05224 Breast cancer
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
   05022 Pathways of neurodegeneration - multiple diseases
    K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
Genes
HSA: 10023(FRAT1)
PTR: 466169(FRAT1)
PPS: 117974699(FRAT1)
GGO: 129524967(FRAT1)
PON: 100461775(FRAT1)
PPYG: 129006110(FRAT1)
NLE: 115834222(FRAT1)
HMH: 116456615(FRAT1)
SSYN: 129468275(FRAT1)
MCC: 705609(FRAT1)
MCF: 102117805(FRAT1)
MTHB: 126962089
MNI: 105478500(FRAT1)
CSAB: 103216335(FRAT1)
CATY: 105581785(FRAT1)
PANU: 101009787(FRAT1)
TGE: 112631657(FRAT1)
RRO: 104682839(FRAT1)
RBB: 108534484(FRAT1)
TFN: 117069266
PTEH: 111538755(FRAT1)
CJC: 108594172(FRAT1)
SBQ: 101053270(FRAT1)
CIMI: 108285514(FRAT1)
ANAN: 105708138(FRAT1)
MMUR: 105873000(FRAT1)
LCAT: 123650181(FRAT1)
PCOQ: 105818472(FRAT1)
OGA: 100960572(FRAT1)
MMU: 14296(Frat1) 27412(Peg12)
MCAL: 110285589(Frat1) 110299413
MPAH: 110324178 110329160(Frat1)
RNO: 103691373(Frat1) 308692(Peg12)
MCOC: 116100551 116103835(Frat1)
ANU: 117696584 117698570(Frat1)
MUN: 110556643
MAUA: 101839069(Frat1)
PROB: 127233368(Frat1)
PLEU: 114706884
MORG: 121454457(Frat1)
MFOT: 126504573
AAMP: 119822495(Frat1)
NGI: 103733205(Frat1)
HGL: 101724371(Frat1)
CCAN: 109695300(Frat1)
DORD: 105986579(Frat1)
DSP: 122115816(Frat1)
PLOP: 125346207(Frat1)
NCAR: 124984918
MMMA: 107149936(Frat1)
OCU: 103351400
OPI: 101520075(FRAT1)
GVR: 103590897(FRAT1)
CFA: 486819(FRAT1)
CLUD: 112672132
VVP: 112908489(FRAT1)
VLG: 121476462
NPO: 129523328
AML: 105236609(FRAT1)
UMR: 121101236(FRAT1)
UAH: 113251777(FRAT1)
UAR: 123783969(FRAT1)
ELK: 111145138
LLV: 125085157
MNP: 132015350(FRAT1) 132016662
MLK: 131828593(FRAT1)
NVS: 122898988(FRAT1)
ORO: 101365631(FRAT1)
EJU: 114205207(FRAT1)
ZCA: 113914236(FRAT1)
MLX: 118024369(FRAT1) 118024374(FRAT2)
NSU: 123325104
LWW: 102743927
FCA: 101087686(FRAT1)
PYU: 121037465(FRAT1)
PCOO: 112854825
PBG: 122493080(FRAT1)
PVIV: 125147395(FRAT1)
LRUF: 124507027
PPAD: 109272709(FRAT1)
PUC: 125932834
AJU: 113600380
HHV: 120230551
BTA: 505664(FRAT1)
BOM: 102269752(FRAT1)
BIU: 109553209(FRAT1)
BBUB: 102407886(FRAT1)
CHX: 108634040(FRAT1)
OAS: 105609583(FRAT1)
BTAX: 128067878(FRAT1)
ODA: 120873964(FRAT1)
CCAD: 122446679(FRAT1)
MBEZ: 129555496(FRAT1)
SSC: 110256598(FRAT1)
CFR: 116667094(FRAT1)
CDK: 105084375(FRAT1)
VPC: 102534188(FRAT1)
BACU: 103015059(FRAT1)
BMUS: 118882841(FRAT1)
LVE: 103084685(FRAT1)
OOR: 101290120(FRAT1)
DLE: 111172443(FRAT1)
PCAD: 102982313(FRAT1)
PSIU: 116741586(FRAT1)
NASI: 112392971
ECB: 111773577(FRAT1)
EAI: 106844950(FRAT1)
MMYO: 118669908(FRAT1)
MLF: 102425438
MDT: 132214197(FRAT1)
PKL: 118719347(FRAT1)
EFUS: 103288636(FRAT1)
SHON: 118990288(FRAT1)
AJM: 119044523(FRAT1)
PDIC: 114495951(FRAT1)
PHAS: 123828894(FRAT1)
MMF: 118632337(FRAT1)
PPAM: 129077272(FRAT1)
HAI: 109379591(FRAT1)
RFQ: 117036216(FRAT1)
PALE: 102896339
PGIG: 120609253(FRAT1)
RAY: 107520415(FRAT1)
MJV: 108399888(FRAT1)
TOD: 119233502(FRAT1)
SETR: 125994798
LAV: 100669466(FRAT1)
TMU: 101352077
DNM: 101447222(FRAT1)
GAS: 123234296
SHR: 105749059
TVP: 118829207
PVT: 110074800
SKO: 100303596(frat1)
 » show all
Reference
  Authors
van Amerongen R, van der Gulden H, Bleeker F, Jonkers J, Berns A
  Title
Characterization and functional analysis of the murine Frat2 gene.
  Journal
J Biol Chem 279:26967-74 (2004)
DOI:10.1074/jbc.M400439200
  Sequence
[mmu:14296]

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