KEGG   ORTHOLOGY: K03120
Entry
K03120                      KO                                     

Name
TBP, tbp
Definition
transcription initiation factor TFIID TATA-box-binding protein
Pathway
ko03022  Basal transcription factors
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05203  Viral carcinogenesis
Disease
H00063  Spinocerebellar ataxia (SCA)
H01243  Huntington disease-like syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
  09164 Neurodegenerative disease
   05016 Huntington disease
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
   05017 Spinocerebellar ataxia
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
   05165 Human papillomavirus infection
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
   03021 Transcription machinery
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
  RNA polymerase III system
   Basal transcription factors
    TFIIIB
     K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
  RNA polymerase I system
   Basal transcription factors
    SL1/TIF-1B
     K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
Genes
HSA: 387332(TBPL2) 6908(TBP) 9519(TBPL1)
PTR: 452923(TBPL2) 463010(TBPL1) 738472(TBP)
PPS: 100977267(TBP) 100982500(TBPL1) 100986094(TBPL2)
GGO: 101125579(TBP) 101131473(TBPL1) 101134300(TBPL2)
PON: 100173239(TBPL1) 100437756(TBP) 100454972(TBPL2)
NLE: 100585659(TBPL1) 100593579(TBPL2) 100607796(TBP)
MCC: 696258(TBP) 697371(TBPL2) 713262(TBPL1)
MCF: 101866697(TBP) 101925911(TBPL1) 102117283(TBPL2)
CSAB: 103229900(TBPL2) 103240341(TBPL1) 103241044(TBP)
RRO: 104669139(TBPL2) 104674401(TBP) 104678239(TBPL1)
RBB: 108530671(TBPL2) 108531832(TBPL1) 108541285(TBP)
CJC: 100401601(TBPL1) 100405104(TBP) 100410605(TBPL2)
SBQ: 101038765(TBPL2) 101040658(TBP) 101046128(TBPL1)
MMU: 21374(Tbp) 227606(Tbpl2) 237336(Tbpl1)
MCAL: 110284117(Tbp) 110289978(Tbpl2) 110303300(Tbpl1)
MPAH: 110319015(Tbpl2) 110338035(Tbpl1) 110338047(Tbp)
RNO: 117526(Tbp) 680050(Tbpl2) 689030(Tbpl1)
MUN: 110550423(Tbpl1) 110561127(Tbp) 110563414(Tbpl2)
CGE: 100751579(Tbp) 100768754(Tbpl1)
NGI: 103724914(Tbpl1) 103739216(Tbpl2) 103742347(Tbp)
HGL: 101702646(Tbp) 101708931(Tbpl1) 101724326(Tbpl2)
CCAN: 109697941(Tbpl1) 109698475(Tbpl2) 109700768(Tbp) 109702231
OCU: 100343365(TBP) 100346981(TBPL1) 100349947(TBPL2)
TUP: 102470240(TBP) 102486811(TBPL2) 102498567(TBPL1)
CFA: 476209(TBPL1) 611011(TBPL2) 611193(TBP)
VVP: 112919452(TBPL1) 112921404(TBPL2) 112925203(TBP)
AML: 100468425(TBPL1) 100482953(TBP) 105242046(TBPL2)
UMR: 103660778(TBP) 103663386(TBPL1) 103673156(TBPL2)
UAH: 113242339(TBPL2) 113247109(TBP) 113259467(TBPL1)
ORO: 101377495(TBPL1) 101382669(TBP) 101386002(TBPL2)
FCA: 101084200(TBP) 101093111(TBPL2) 101098461(TBPL1)
PTG: 102948730(TBP) 102951578(TBPL2) 102967012(TBPL1)
PPAD: 109245458(TBP) 109249905(TBPL1) 109268204(TBPL2)
AJU: 106976865(TBPL1) 106978655(TBP) 106984326(TBPL2)
BTA: 516578(TBP) 613818(TBPL1) 615096(TBPL2)
BOM: 102270403 102271474(TBPL1) 102272125(TBPL2) 102283352(TBP)
BIU: 109563966(TBPL1) 109564392(TBPL2) 109565755(TBP)
BBUB: 102394310(TBPL2) 102395512(TBP) 102407125(TBPL1)
CHX: 102173392(TBPL2) 102176044(TBPL1) 102182309(TBP)
OAS: 100144760(TBP) 101107201(TBPL1) 101113500(TBPL2)
SSC: 100125545 100154426(TBPL2) 100517563(TBPL1) 110259740(TBP)
CFR: 102516470(TBPL1) 102522130(TBPL2) 102523054(TBP)
CDK: 105091446(TBPL2) 105093873(TBP) 105096361(TBPL1)
BACU: 102998040(TBPL2) 103014400(TBP) 103015815(TBPL1)
LVE: 103073021(TBPL1) 103077940(TBPL2) 103083522(TBP)
OOR: 101269987(TBP) 101282027(TBPL1) 101285029(TBPL2)
DLE: 111165948(TBPL1) 111168028(TBP) 111173316(TBPL2)
PCAD: 102976096(TBP) 102986226(TBPL1) 102986759(TBPL2)
ECB: 100049846(TBP) 100067729(TBPL1)
EPZ: 103558053 103561390(TBPL1) 103561928(TBPL2) 103564699(TBP)
EAI: 106824399 106826988(TBPL2) 106827776(TBP)
MYB: 102249491(TBPL2) 102249574(TBPL1) 102255795 102257340(TBP)
MYD: 102754954(TBP) 102755572(TBPL2) 102766792(TBPL1)
MNA: 107525977(TBPL2) 107530996(TBPL1) 107537027(TBP)
HAI: 109371923(TBPL1) 109384600(TBPL2) 109391700(TBP)
DRO: 112297070(TBPL1) 112297176(TBP) 112311996(TBPL2)
PALE: 102883227(TBP) 102892522(TBPL1) 102898783(TBPL2)
RAY: 107500158(TBP) 107510913(TBPL2) 107516172(TBPL1)
MJV: 108386588(TBPL1) 108394219(TBPL2) 108402561(TBP)
LAV: 100665593(TBPL2) 100668871(TBPL1) 100676280(TBP)
MDO: 100025773(TBPL2) 100028736(TBP) 100031385(TBPL1)
SHR: 100915353(TBP) 100925485(TBPL2) 100934885(TBPL1)
PCW: 110197964(TBP) 110208261(TBPL2) 110208901(TBPL1)
OAA: 100075429(TBPL1) 100082878(TBPL2) 100091633(TBP)
GGA: 395517(TBPL1) 395995(TBP) 776269(TBPL2)
MGP: 100539594(TBPL1) 100543138(TBP) 100548904(TBPL2)
CJO: 107311439(TBP) 107311698(TBPL1) 107315449(TBPL2)
NMEL: 110395422(TBP) 110395500(TBPL1) 110401939(TBPL2)
APLA: 101799558(TBP) 101802161(TBPL1) 101805356(TBPL2)
ACYG: 106032507(TBPL1) 106044065(TBPL2) 106044573(TBP)
TGU: 100227951(TBP) 100228722(TBPL2) 100232377(TBPL1)
LSR: 110468905(TBP) 110472716(TBPL2) 110476055(TBPL1)
SCAN: 103818494(TBP) 103820547(TBPL1) 103826337(TBPL2)
GFR: 102037899(TBPL1) 102038501(TBP) 102043279(TBPL2)
FAB: 101809723(TBPL1) 101813419(TBPL2) 101815196(TBP)
PHI: 102101509(TBPL1) 102103904(TBP) 102108098(TBPL2)
PMAJ: 107202134(TBP) 107202413(TBPL1) 107206055(TBPL2)
CCAE: 111926903(TBP) 111927651(TBPL1) 111929675(TBPL2)
CCW: 104684321(TBP) 104687579(TBPL2) 104690487(TBPL1)
ETL: 114064631(TBP) 114065226(TBPL1) 114071553(TBPL2)
FPG: 101919427(TBP) 101923906(TBPL1) 101924971(TBPL2)
FCH: 102048257(TBP) 102049002(TBPL2) 102052523(TBPL1)
CLV: 102087538(TBPL2) 102090059(TBP) 102094429(TBPL1)
EGZ: 104122990(TBPL2) 104131034(TBP) 104131206(TBPL1)
NNI: 104008827(TBPL1) 104017848(TBP) 104019429(TBPL2)
ACUN: 113477751(TBP) 113478396(TBPL1) 113480696(TBPL2)
PADL: 103912696(TBPL1) 103915997(TBPL2) 103921251(TBP)
AAM: 106487349(TBP) 106493665(TBPL2) 106498016(TBPL1)
ASN: 102369278(TBPL2) 102370932(TBPL1) 102387742(TBP)
AMJ: 102566345(TBPL2) 102573683(TBP) 102576649(TBPL1)
PSS: 102449569(TBPL1) 102454295(TBPL2) 102463074(TBP)
CMY: 102932054(TBPL1) 102942198(TBPL2) 102946593(TBP)
CPIC: 101935676(TBPL1) 101944464(TBPL2) 101949391(TBP)
ACS: 100551656(tbp) 100567952(tbpl1) 103280203(tbpl2)
PVT: 110083079(TBP) 110091273(TBPL1) 110091700(TBPL2)
PBI: 103055440(TBPL1) 103056467(TBPL2) 103063294(TBP)
PMUR: 107289909(TBPL1) 107290182(TBP) 107302959(TBPL2)
TSR: 106538559(TBP) 106540711(TBPL1)
PMUA: 114594161(TBPL1) 114594363(TBP) 114596603(TBPL2)
GJA: 107111165(TBPL2) 107113464(TBP) 107114283(TBPL1)
XLA: 108704788 387333(tbpl2.L) 399086(tbpl1.L) 399465(tbp.L) 503680(tbp.S)
XTR: 448323(tbpl1) 549093(tbp) 550063(tbpl2)
NPR: 108787482(TBP) 108791903(TBPL2) 108794120(TBPL1)
DRE: 368882(tbp) 403035(tbpl1) 407713(tbpl2)
IPU: 100528854(tbpl1) 108263571(tbp) 108269646(tbpl2)
PHYP: 113538839 113540337(tbp) 113545526(tbpl1)
AMEX: 103031726 103034133(tbp)
EEE: 113579346(tbpl2) 113582045(tbp) 113591529(tbpl1)
NCC: 104955592(tbp) 104965345 104965734(tbpl1)
OLA: 100049222(tbp) 101165520(tbpl2) 101172784(tbpl1) 101174576
XCO: 114143463(tbp) 114152043 114158764(tbpl1)
PRET: 103457664(tbpl1) 103458079(tbpl2) 103462815(tbp) 103481886
CVG: 107084871 107092133(tbp) 107097381(tbpl1)
NFU: 107377488(tbpl1) 107381176(tbp) 107387238 107391905(tbpl2)
ALIM: 106513144(tbp) 106524887(tbpl1) 106527305(tbpl2)
CSEM: 103378603(tbp) 103381809(tbpl2) 103398701(tbpl1)
POV: 109632489(tbpl1) 109636833(tbp) 109647485
SDU: 111217913(tbp) 111237051 111237150(tbpl2) 111240368(tbpl1)
BPEC: 110154289(tbpl1) 110167125 110175522(tbp)
ELS: 105018006(tbpl1) 105021199(tbp) 105024716
SFM: 108921051(tbpl1) 108932905(tbp) 108941464
PKI: 111837018 111841258(tbpl1) 111849052(tbp)
RTP: 109927050(tbp) 109927346(tbpl2) 109937407(tbpl1)
SKO: 100369885
DME: Dmel_CG18009(Trf2) Dmel_CG7562(Trf) Dmel_CG9874(Tbp)
DSI: Dsimw501_GD23502(Dsim_GD23502) Dsimw501_GD25175(Dsim_GD25175) Dsimw501_GD27042(Dsim_GD27042)
CEL: CELE_F39H11.2(tlf-1) CELE_T20B12.2(tbp-1)
CBR: CBG09138(Cbr-tbp-1) CBG12345(Cbr-tlf-1)
OBI: 106870472
NVE: 5516059
EPA: 110232658
AMIL: 114954907
PDAM: 113670375
SPIS: 111324061
DGT: 114519935
HMG: 100209233
AQU: 100636064
ATH: AT1G55520(TBP2) AT3G13445(TBP1)
CPAP: 110814981
VRA: 106754936
VAR: 108346239
VUN: 114167006
LJA: Lj3g3v1411740.1(Lj3g3v1411740.1)
CSV: 101216807
CMO: 103492411
MCHA: 111016510
VVI: 100243302
SLY: 101254627
SOT: 102583666(TBP) 102596656
DOSA: Os03t0657000-01(Os03g0657000) Os10t0432300-01(Os10g0432300) Os12t0580300-01(Os12g0580300)
ATS: 109747831(LOC109747831) 109759848(LOC109759848) 109767111(LOC109767111)
ZMA: 103626103 103631568 542240(tbp1) 542241(tbp2)
VCN: VOLCADRAFT_73605(tbpA)
MNG: MNEG_6032
APRO: F751_4033
OLU: OSTLU_26716(GTF3501)
SCE: YER148W(SPT15)
ERC: Ecym_5549
KMX: KLMA_20021(SPT15)
NCS: NCAS_0A03870(NCAS0A03870)
NDI: NDAI_0E03380(NDAI0E03380)
TPF: TPHA_0A02110(TPHA0A02110)
TBL: TBLA_0B08050(TBLA0B08050)
TDL: TDEL_0B04130(TDEL0B04130)
KAF: KAFR_0B02330(KAFR0B02330)
PIC: PICST_38880(SPT15)
CAL: CAALFM_C110660WA(TBP1)
SLB: AWJ20_3012(SPT15)
NCR: NCU04770
NTE: NEUTE1DRAFT118055(NEUTE1DRAFT_118055)
MGR: MGG_15601
TRE: TRIREDRAFT_49918(tf2d)
MAW: MAC_03480
MAJ: MAA_02226
CMT: CCM_04604
MBE: MBM_05886
ANI: AN4976.2
ANG: ANI_1_550144(An16g03940)
CIM: CIMG_11148(CIMG03555)
ABE: ARB_05452
TVE: TRV_02367
PTE: PTT_19076
SPO: SPAC29E6.08(tbp1)
CNE: CNH01090
CNB: CNBL1030
TASA: A1Q1_08290
ABP: AGABI1DRAFT111611(AGABI1DRAFT_111611)
ABV: AGABI2DRAFT44722(AGABI2DRAFT_44722)
MGL: MGL_3672
MRT: MRET_1674
DDI: DDB_G0275617(tbpA)
DFA: DFA_02538(tbpA)
EHI: EHI_020610 EHI_077240(40.t00019) EHI_112050(115.t00027)
PCB: PCHAS_110550(PC402314.00.0)
TAN: TA03075
TPV: TP01_0630
BBO: BBOV_IV002970(21.m02732)
CPV: cgd8_2030
TGO: TGME49_258680(TBP2)
FCY: FRACYDRAFT_197422(TBP_1)
TPS: THAPSDRAFT_264095(TF2D2)
AAF: AURANDRAFT_33824(GTF)
MJA: MJ_0507
MMP: MMP0257(tbp)
MMD: GYY_01310
MMAK: MMKA1_02620(tbp)
MMAO: MMOS7_02900(tbp) MMOS7_08070(tbp)
MAE: Maeo_0186
MVO: Mvol_1694
MTH: MTH_1627
MMG: MTBMA_c02120(tbp)
METC: MTCT_1486
MWO: MWSIV6_0173(tbp)
METE: tca_01577
MST: Msp_1097(tbp)
MRU: mru_0387(tbp)
MSI: Msm_0720
MEB: Abm4_0183(tbp)
MMIL: sm9_2158(tbp)
MEYE: TL18_01085
MOL: YLM1_0058
METH: MBMB1_0293(tbp)
MFC: BRM9_1982(tbp)
MFI: DSM1535_0174(tbp)
MCUB: MCBB_0562(tbp)
MFV: Mfer_0180
MKA: MK0839(spt15)
AFU: AF_0373
FPL: Ferp_0973
GAC: GACE_0907
GAH: GAH_01881
TAC: Ta0199
TVO: TVG1467237(TVG1467237)
PTO: PTO0506
FAI: FAD_1781
CDIV: CPM_0506
MEAR: Mpt1_c03620(tbp2)
MARC: AR505_0740
ABI: Aboo_0971
PFU: PF1295
PFI: PFC_05690
PHO: PH1009(PH1009)
PAB: PAB1726
PYN: PNA2_1532
PYS: Py04_0907
TKO: TK0132
TON: TON_1309
TGA: TGAM_0446(tbp-1) TGAM_0829(tbp-2)
TSI: TSIB_0138
THM: CL1_1411
TLT: OCC_11587
THS: TES1_1341
TNU: BD01_1715
TEU: TEU_00535
PPAC: PAP_05285
MAC: MA_0179(tbp-2) MA_0278(tbp-3) MA_4331(tbp-1)
METM: MSMTP_0306
MTHR: MSTHT_1609
MTHE: MSTHC_1680
MBU: Mbur_1496
MMET: MCMEM_2017
MMH: Mmah_1813
MTP: Mthe_0152
MCJ: MCON_2012(tbpB) MCON_3427(tbpA)
MHI: Mhar_0355
MEMA: MMAB1_1302(tbp) MMAB1_1665(tbp)
MPD: MCP_0130(tbp-1) MCP_1285 MCP_1871(tbp-2)
MEZ: Mtc_0357(tbpE)
RCI: RCIX1238(tbpE)
HAL: AAC82815.1 AAC82955.1 VNG_2243G(tbpE) VNG_6037G(tbpA) VNG_6050G(tbpB_1) VNG_6140G(tbpC) VNG_6438G(tbpF) VNG_6476G(tbpB_2) tbpB(tbpB) tbpC(tbpC) tbpD(tbpD)
HSL: OE_4146F(tbpE) OE_7045F(tbpA) OE_7186F(tbpC1) OE_7214R(tbpD1) OE_8017F(tbpC2) OE_8046R(tbpD2)
HHB: Hhub_3598(tbp1) Hhub_4263(tbp2) Hhub_5066(tbp3) Hhub_6115(tbp4)
HALH: HTSR_0163
HHSR: HSR6_0159
HMA: rrnAC0681(tbpE)
HHI: HAH_1334(tbp)
NPH: NP_1064A(tbp)
NMO: Nmlp_1125(tbp1) Nmlp_1275(tbp4) Nmlp_2511(tbp3) Nmlp_2517(tbp2)
HMU: Hmuk_0721
HALL: LC1Hm_3233(spt15)
HWA: HQ_2527A(tbpA) HQ_3410A(tbpB)
HWC: Hqrw_1388(tbpC) Hqrw_2827(tbpA) Hqrw_3936(tbpB) Hqrw_5072(tbpE)
HVO: HVO_0158(tbp1) HVO_1727(tbp2) HVO_2268(tbp4) HVO_B0382(tbp3)
HME: HFX_0160(tbp1) HFX_1819(tbp2) HFX_2167(tbp3) HFX_5297(tbp4)
HDF: AArcSl_0890(tbp) AArcSl_1300(tbp2) AArcSl_2335(tbp3) AArcSl_2456(tbp4)
HTU: Htur_0133
NMG: Nmag_1863(tbp)
NAT: NJ7G_0584
SALI: L593_02770
APE: APE_1862.1(tbp)
ACJ: ACAM_1168(tbp)
SMR: Smar_1322
IHO: Igni_0989
IIS: EYM_03155
DKA: DKAM_0275
TAG: Tagg_0216
IAG: Igag_0988
HBU: Hbut_0934
STO: STK_12750(tbp)
SSO: SSO0951(tfIID)
SOL: Ssol_1927
SSOA: SULA_1959
SSOL: SULB_1960
SSOF: SULC_1958
SAI: Saci_1336(tbp)
SID: M164_1259
SII: LD85_1387
SIH: SiH_1220
SIR: SiRe_1138
SIC: SiL_1135
MSE: Msed_1728
MCN: Mcup_0499
AHO: Ahos_1398
STEP: IC006_1159
PAI: PAE2164
PIS: Pisl_0807
PCL: Pcal_1078
PAS: Pars_0806
PYR: P186_0409
POG: Pogu_1526
TNE: Tneu_1352
CMA: Cmaq_1206
TTN: TTX_0178(tbp)
TUZ: TUZN_1169
VDI: Vdis_0824
VMO: VMUT_1670
TPE: Tpen_0293
ASC: ASAC_0197
ACIA: SE86_01770
NID: NPIRD3C_1657(tbp) NPIRD3C_2166(tbp)
NCT: NMSP_0240(tbp_1) NMSP_0942(tbp_2) NMSP_1077(tbp_3)
NGA: Ngar_c34620(tbp)
NVN: NVIE_017500(tbp)
NEV: NTE_00618
NFN: NFRAN_3023(tbp)
NCV: NCAV_0293(tbp)
NBV: T478_0996(tbp) T478_1209(tbp)
NDV: NDEV_1298(tbp) NDEV_1817(tbp)
KCR: Kcr_1466
BARC: AOA65_1662(tbp)
BARB: AOA66_1623(tbp)
CCAI: NAS2_1528
NEQ: NEQ039
NAA: Nps_00080
LOKI: Lokiarch_10300(tbp_1) Lokiarch_31920(tbp_2)
PSYT: DSAG12_01749(tbp_1) DSAG12_01754(tbp_2) DSAG12_03033(tbp_3) DSAG12_03530(tbp_4)
 » show all
Reference
  Authors
Friedrich JK, Panov KI, Cabart P, Russell J, Zomerdijk JC
  Title
TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter.
  Journal
J Biol Chem 280:29551-8 (2005)
DOI:10.1074/jbc.M501595200
  Sequence
[hsa:6908]
Reference
  Authors
Martinez E
  Title
Multi-protein complexes in eukaryotic gene transcription.
  Journal
Plant Mol Biol 50:925-47 (2002)
DOI:10.1023/A:1021258713850
  Sequence
[sce:YER148W]
Reference
PMID:2363050
  Authors
Peterson MG, Tanese N, Pugh BF, Tjian R
  Title
Functional domains and upstream activation properties of cloned human TATA binding protein.
  Journal
Science 248:1625-30 (1990)
DOI:10.1126/science.2363050
  Sequence
[hsa:6908]

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