ORTHOLOGY: K03176 Help
Entry
Symbol
NTRK1, TRKA
Name
neurotrophic tyrosine kinase receptor type 1 [EC:
2.7.10.1 ]
Pathway
map04750 Inflammatory mediator regulation of TRP channels
map05202 Transcriptional misregulation in cancer
map05230 Central carbon metabolism in cancer
Disease
H00265 Hereditary sensory and autonomic neuropathy
H01836 Congenital pain insensitivity with anhidrosis
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
04014 Ras signaling pathway
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
04020 Calcium signaling pathway
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
04151 PI3K-Akt signaling pathway
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
05202 Transcriptional misregulation in cancer
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
05230 Central carbon metabolism in cancer
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09162 Cancer: specific types
05216 Thyroid cancer
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
Protein kinases [BR:ko01001 ]
Receptor tyrosine kinases (RTK)
TRK family [OT]
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Tacconelli A, Farina AR, Cappabianca L, Desantis G, Tessitore A, Vetuschi A, Sferra R, Rucci N, Argenti B, Screpanti I, Gulino A, Mackay AR
Title
TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma.
Journal
Sequence