KEGG ORTHOLOGY: K03268

ORTHOLOGY: K03268

Entry

K03268            Tight     KO

Symbol

todC1, bedC1, tcbAa

Name

benzene/toluene/chlorobenzene dioxygenase subunit alpha [EC:1.14.12.3 1.14.12.11 1.14.12.26]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map00625

Chloroalkane and chloroalkene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00547

Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol

Reaction

R03543

benzene,NADH:oxygene 1,2-oxidoreductase

R03559

toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R05429

1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06831

1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06856

chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R09151

trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)

R09152

trichloroethene,NADH:oxygen oxidoreductase (formate-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
   00625 Chloroalkane and chloroalkene degradation
    K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
   00361 Chlorocyclohexane and chlorobenzene degradation
    K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
   00623 Toluene degradation
    K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.3  benzene 1,2-dioxygenase
     K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
    1.14.12.11  toluene dioxygenase
     K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
    1.14.12.26  chlorobenzene dioxygenase
     K03268  todC1, bedC1, tcbAa; benzene/toluene/chlorobenzene dioxygenase subunit alpha
Dioxygenases [br01602.html]
Dioxygenases in aromatic ring cleavage
  K03268

Other DBs

GO:	0018619 0018624 0018609

Genes

PPF:

Pput_2881

PPX:	T1E_4266(todC1)

PMON:

PMOT:

PASI:

BPT:

ATEM:

AG:	AAC43632(tcbAa)

Reference

PMID:8824602

Authors

Fong KP, Goh CB, Tan HM

Title

Characterization and expression of the plasmid-borne bedD gene from Pseudomonas putida ML2, which codes for a NAD+-dependent cis-benzene dihydrodiol dehydrogenase.

Journal

J Bacteriol 178:5592-601 (1996)
DOI:10.1128/JB.178.19.5592-5601.1996

Reference

PMID:2670929

Authors

Zylstra GJ, Gibson DT

Title

Toluene degradation by Pseudomonas putida F1. Nucleotide sequence of the todC1C2BADE genes and their expression in Escherichia coli.

Journal

J Biol Chem 264:14940-6 (1989)

Sequence

[ppf:Pput_2881]

Reference

PMID:8626733

Authors

Werlen C, Kohler HP, van der Meer JR

Title

The broad substrate chlorobenzene dioxygenase and cis-chlorobenzene dihydrodiol dehydrogenase of Pseudomonas sp. strain P51 are linked evolutionarily to the enzymes for benzene and toluene degradation.

Journal

J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009

Sequence

[ag:AAC43632]

All links

Ontology (6)   
   KEGG BRITE (3)   
   GO (3)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Chemical reaction (16)   
   KEGG ENZYME (3)   
   KEGG REACTION (7)   
   KEGG RCLASS (6)   
Gene (9)   
   KEGG GENES (8)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (49)   

Download RDF

ORTHOLOGY: K18090

Entry

K18090            Tight     KO

Symbol

todA, tcbAd

Name

benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component [EC:1.18.1.3 1.18.1.-]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map00625

Chloroalkane and chloroalkene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00547

Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol

Reaction

R03543

benzene,NADH:oxygene 1,2-oxidoreductase

R03559

toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R05429

1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06831

1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06856

chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R09151

trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)

R09152

trichloroethene,NADH:oxygen oxidoreductase (formate-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00625 Chloroalkane and chloroalkene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00361 Chlorocyclohexane and chlorobenzene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
   00623 Toluene degradation
    K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.3  ferredoxin---NAD+ reductase
     K18090  todA, tcbAd; benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
Dioxygenases in aromatic ring cleavage
  K18090

Other DBs

COG:

COG0446

GO:

0008860

Genes

PPF:

Pput_2878

PPX:	T1E_4269(tobA)

PMON:

PMOT:

PASI:

BPT:

ATEM:

AG:	AAC43635(tcbAd)

Reference

PMID:8626733

Authors

Werlen C, Kohler HP, van der Meer JR

Title

Journal

J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009

Sequence

[ag:AAC43635]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Chemical reaction (14)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
   KEGG RCLASS (6)   
Gene (9)   
   KEGG GENES (8)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (44)   

Download RDF

ORTHOLOGY: K16268

Entry

K16268            Tight     KO

Symbol

todC2, bedC2, tcbAb

Name

benzene/toluene/chlorobenzene dioxygenase subunit beta [EC:1.14.12.3 1.14.12.11 1.14.12.26]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map00625

Chloroalkane and chloroalkene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00547

Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol

Reaction

R03543

benzene,NADH:oxygene 1,2-oxidoreductase

R03559

toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R05429

1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06831

1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06856

chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R09151

trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)

R09152

trichloroethene,NADH:oxygen oxidoreductase (formate-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
   00625 Chloroalkane and chloroalkene degradation
    K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
   00623 Toluene degradation
    K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.3  benzene 1,2-dioxygenase
     K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
    1.14.12.11  toluene dioxygenase
     K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
    1.14.12.26  chlorobenzene dioxygenase
     K16268  todC2, bedC2, tcbAb; benzene/toluene/chlorobenzene dioxygenase subunit beta
Dioxygenases [br01602.html]
Dioxygenases in aromatic ring cleavage
  K16268

Other DBs

GO:	0018619 0018624 0018609

Genes

PPF:

Pput_2880

PPX:	T1E_4267(todC2)

PMON:

PMOT:

PASI:

BPT:

ATEM:

AG:	AAC43633(tcbAb)

Reference

PMID:8824602

Authors

Fong KP, Goh CB, Tan HM

Title

Characterization and expression of the plasmid-borne bedD gene from Pseudomonas putida ML2, which codes for a NAD+-dependent cis-benzene dihydrodiol dehydrogenase.

Journal

J Bacteriol 178:5592-601 (1996)
DOI:10.1128/JB.178.19.5592-5601.1996

Reference

PMID:2670929

Authors

Zylstra GJ, Gibson DT

Title

Toluene degradation by Pseudomonas putida F1. Nucleotide sequence of the todC1C2BADE genes and their expression in Escherichia coli.

Journal

J Biol Chem 264:14940-6 (1989)

Sequence

[ppf:Pput_2880]

Reference

PMID:8626733

Authors

Werlen C, Kohler HP, van der Meer JR

Title

Journal

J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009

Sequence

[ag:AAC43633]

All links

Ontology (6)   
   KEGG BRITE (3)   
   GO (3)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Chemical reaction (16)   
   KEGG ENZYME (3)   
   KEGG REACTION (7)   
   KEGG RCLASS (6)   
Gene (9)   
   KEGG GENES (8)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (49)   

Download RDF

ORTHOLOGY: K18089

Entry

K18089            Tight     KO

Symbol

todB, tcbAc

Name

benzene/toluene/chlorobenzene dioxygenase ferredoxin component

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map00625

Chloroalkane and chloroalkene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00547

Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol

Reaction

R03543

benzene,NADH:oxygene 1,2-oxidoreductase

R03559

toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R05429

1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06831

1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R06856

chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

R09151

trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)

R09152

trichloroethene,NADH:oxygen oxidoreductase (formate-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18089  todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component
   00625 Chloroalkane and chloroalkene degradation
    K18089  todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component
   00361 Chlorocyclohexane and chlorobenzene degradation
    K18089  todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component
   00623 Toluene degradation
    K18089  todB, tcbAc; benzene/toluene/chlorobenzene dioxygenase ferredoxin component
Dioxygenases [br01602.html]
Dioxygenases in aromatic ring cleavage
  K18089

Other DBs

COG:

COG2146

Genes

PPF:

Pput_2879

PPX:	T1E_4268(tobB)

PMON:

PMOT:

PASI:

BPT:

ATEM:

AG:	AAC43634(tcbAc)

Reference

PMID:8626733

Authors

Werlen C, Kohler HP, van der Meer JR

Title

Journal

J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009

Sequence

[ag:AAC43634]

All links

Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Chemical reaction (13)   
   KEGG REACTION (7)   
   KEGG RCLASS (6)   
Gene (9)   
   KEGG GENES (8)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (41)   

Download RDF

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