KEGG   ORTHOLOGY: K03283
Entry
K03283                      KO                                     

Name
HSPA1s
Definition
heat shock 70kDa protein 1/2/6/8
Pathway
ko03040  Spliceosome
ko04010  MAPK signaling pathway
ko04141  Protein processing in endoplasmic reticulum
ko04144  Endocytosis
ko04213  Longevity regulating pathway - multiple species
ko04612  Antigen processing and presentation
ko04915  Estrogen signaling pathway
ko05020  Prion disease
ko05134  Legionellosis
ko05145  Toxoplasmosis
ko05162  Measles
ko05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09171 Infectious disease: bacterial
   05134 Legionellosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09164 Neurodegenerative disease
   05020 Prion disease
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03009 Ribosome biogenesis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03110 Chaperones and folding catalysts
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   04131 Membrane trafficking
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03051 Proteasome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03029 Mitochondrial biogenesis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Spliceosome [BR:ko03041]
 Complex B
  Other components
   Prp19 complex
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 Complex C
  Other components
   Prp19-CDC5 complex
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Chaperones and folding catalysts [BR:ko03110]
 Heat shock proteins
  HSP70 / DNAK
   K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Proteasome [BR:ko03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Other DBs
TC: 1.A.33.1
Genes
HSA: 3303(HSPA1A) 3304(HSPA1B) 3305(HSPA1L) 3306(HSPA2) 3310(HSPA6) 3312(HSPA8)
PTR: 107973291 112205859(HSPA6) 450139(HSPA2) 451629(HSPA8) 471967 745166 748740
PPS: 100974669(HSPA8) 100984890(HSPA2) 100993344(HSPA1L)
GGO: 101128042(HSPA8) 101129102 101131586 101134225 101135640 101147203(HSPA2) 115932977
PON: 100172711(HSPA8) 100172826(HSPA1A) 100454739(HSPA6) 100458051 100461792(HSPA2) 103890872
NLE: 100579396(HSPA8) 100579550(HSPA6) 100594395 100600172(HSPA2) 100605907(HSPA1L) 115832445(HSPA1A)
MCC: 114669856 574271(HSPA2) 707989(HSPA8) 709412 716633 720001(HSPA6) 720054(HSPA1A)
MCF: 101925240 101926012(HSPA1L) 102116937(HSPA2) 102129925 102131294(HSPA8) 102143176(HSPA6)
CSAB: 103221743(HSPA1B) 103221744(HSPA1L) 103221745(HSPA1A) 103223677(HSPA6) 103229169(HSPA2) 103230925 103248693(HSPA8)
RRO: 104656761(HSPA8) 104659427(HSPA1L) 104671954(HSPA6) 104678130 104678425(HSPA2) 115892023
CJC: 100387043(HSPA2) 100389824(HSPA8) 100393753(HSPA1L) 100406069(HSPA1A) 100407165 100411854(HSPA6)
SBQ: 101032912(HSPA8) 101049152(HSPA1A) 101049467(HSPA1L) 101050736(HSPA6) 101052310(HSPA2)
MMU: 15481(Hspa8) 15482(Hspa1l) 15511(Hspa1b) 15512(Hspa2) 193740(Hspa1a)
MPAH: 110324477(Hspa2) 110327293(Hspa8) 110335695(Hspa1l) 110335998
RNO: 108348108 24468(Hspa8) 24472(Hspa1b) 24963(Hspa1l) 60460(Hspa2)
MUN: 110547779(Hspa2) 110552032(Hspa8) 110554439(Hspa6) 110560130(Hspa1a) 110560143(Hspa1l)
NGI: 103724426(Hspa1l) 103727922(Hspa8) 103745996 103746770(Hspa6) 103749270(Hspa2)
HGL: 101699805(Hspa1l) 101700637 101701238(Hspa6) 101706305(Hspa2) 101708313(Hspa8)
OCU: 100338160(HSPA6) 100348873(HSPA8) 100352959(HSPA2) 100353534(HSPA1L) 100353783 100354037(HSPA1A) 100354435
TUP: 102475976(HSPA2) 102477173(HSPA1L) 102477588(HSPA1A) 102488085(HSPA8) 102492021 102498690(HSPA6) 102499912
CFA: 403612(HSP70) 474850 479406(HSPA8) 480355(HSPA2)
UMR: 103658293(HSPA6) 103662283(HSPA8) 103672248(HSPA2) 103682293(HSPA1A) 103682294 103682295(HSPA1L)
ORO: 101370862(HSPA8) 101371103(HSPA6) 101375744 101376115(HSPA1L) 101376406 101382556(HSPA2)
FCA: 101087422(HSPA8) 101088003(HSPA2) 101091022
PTG: 102954200(HSPA8) 102957873 102962042 102969535(HSPA2) 102971974(HSPA1L) 102972455(HSPA1B)
AJU: 106971332(HSPA2) 106976665(HSPA8) 106983502 106983975(HSPA1L) 113597921
BTA: 281827(HSPA2) 281831(HSPA8) 282254(HSPA1A) 539835(HSPA6) 540190(HSPA1L)
BOM: 102273821(HSPA6) 102273898(HSPA8) 102273909(HSPA2) 102278697 102278977 102285944(HSPA1L)
BIU: 109565247(HSPA2) 109569622(HSPA8) 109577025 109577026 109578169(HSPA6)
BBUB: 102408332(HSPA1L) 102409533 102411242(HSPA8) 102411459(HSPA2) 102411924 102411960(HSPA6)
CHX: 100860849(HSP70.1) 102177850(HSPA1L) 102178315(HSP70) 102182240(HSPA8) 102185412(HSPA6) 102186695(HSPA2)
OAS: 100913152(HSPA1A) 101107064(HSPA6) 101110063(HSPA2) 101112844(HSPA8) 101117117(HSPA1L) 114108605
SSC: 100144518(HSPA1L) 100511890(HSPA8) 100621324(HSPA2) 396648(HSP70.2) 396906(HSPA6)
CFR: 102516558(HSPA6) 102517440(HSPA1L) 102517682 102521559(HSPA8) 102524235(HSPA2) 116658237
BACU: 103008337(HSPA8) 103018136(HSPA2) 103019729 103020014 103020298(HSPA1L)
ECB: 100009679(HSPA8) 100050827(HSPA1A) 100050904 100051595(HSPA6) 100629616(HSPA2) 111769297
EPZ: 103540615 103540859(HSPA6) 103549908(HSPA8) 103559578(HSPA2) 103562493(HSPA1L) 103563286(HSPA1B)
EAI: 106822285 106825061(HSPA1L) 106831112(HSPA6) 106832775(HSPA8) 106840113(HSPA2)
MYB: 102238827(HSPA1A) 102239414(HSPA2) 102239444(HSPA1L) 102256875(HSPA8)
MYD: 102753664(HSPA2) 102764580(HSPA1L) 102764862 102772438 102774775(HSPA8)
PALE: 102880048(HSPA1B) 102880428(HSPA2) 102880632 102893956(HSPA8) 112469030
RAY: 107498469(HSPA1A) 107498470 107498471 107503644(HSPA8) 107509320(HSPA2)
LAV: 100654015(HSPA2) 100656420(HSPA6) 100663257(HSPA8) 100669335(HSPA1A) 100669618 104847136
GGA: 395853(HSPA8) 423504(HSPA2)
MGP: 100541049(HSPA2) 100551334(HSPA8)
CJO: 107315362(HSPA2) 107324229(HSPA8)
NMEL: 110387614(HSPA8) 110401042(HSPA2)
APLA: 101797658(HSPA2) 101801738(HSPA8)
ACYG: 106037266(HSPA2) 106039820(HSPA8)
TGU: 100220962(HSPA2) 100228250(HSPA8)
LSR: 110476561(HSPA8) 110484074(HSPA2)
SCAN: 103823628(HSPA8) 103826375(HSPA2)
GFR: 102038485(HSPA2) 102044992(HSPA8)
FAB: 101809079(HSPA8) 101819046(HSPA2)
PHI: 102102555(HSPA2) 102108461(HSPA8)
PMAJ: 107205698(HSPA2) 107214420(HSPA8)
CCAE: 111929737(HSPA2) 111939329(HSPA8)
CCW: 104687127(HSPA2) 104692112(HSPA8)
ETL: 114063204(HSPA2) 114069869(HSPA8) 114073255
FPG: 101910891(HSPA2) 101911978(HSPA8)
FCH: 102055493(HSPA8) 102056713(HSPA2)
CLV: 102086356(HSPA8) 102092474(HSPA2)
EGZ: 104129209(HSPA8) 104131661(HSPA2)
NNI: 104010138(HSPA2) 104016627(HSPA8)
ACUN: 113480714(HSPA2) 113488543(HSPA8)
PADL: 103924231(HSPA2) 103924822(HSPA8)
AAM: 106483007(HSPA2) 106486146 106490234(HSPA8)
ACS: 100551584(hspa2) 100554002(hspa1a) 100554196 100554364 100564397(hspa8)
XLA: 100037033(hspa1b.L) 100337574(hsc70.ii) 100381020(hspa1a.S) 108696811 379319(hspa8.L) 379760(hspa1l.S) 398343(hsp70.L) 444468(hspa2.L)
XTR: 100037899(hsp70) 100485441(hspa1b) 100488052(hspa1a) 100496320(hspa8) 100496396(hspa2) 779883(hspa1l)
DRE: 100126123(hsp70.1) 100535101(hsp70.2) 30671(hsp70.3) 393586(hsc70) 560210(hsp70l) 562935(hspa8b) 573376(hspa8) 798846(hspa1b)
KMR: 108228473 108236850(hspa1b) 108241987(hsc70) 108243113(hspa8b) 108249515(hspa8) 108251650 108251765
CIN: 100187210 619232(hsp70)
DME: Dmel_CG18743(Hsp70Ab) Dmel_CG31359(Hsp70Bb) Dmel_CG31366(Hsp70Aa) Dmel_CG31449(Hsp70Ba) Dmel_CG4264(Hsc70-4) Dmel_CG5436(Hsp68) Dmel_CG5834 Dmel_CG6489(Hsp70Bc) Dmel_CG7756(Hsc70-2) Dmel_CG8937(Hsc70-1)
DSI: Dsimw501_GD14466(Dsim_GD14466) Dsimw501_GD18326(Dsim_Hsp68) Dsimw501_GD18878(Dsim_GD18878) Dsimw501_GD18998(Dsim_Hsc70-4) Dsimw501_GD20560(Dsim_Hsp70Ba) Dsimw501_GD20621(Dsim_Hsp70Aa)
AME: 409418(Hsc70-4) 410620
CEL: CELE_C12C8.1(hsp-70) CELE_F11F1.1(F11F1.1) CELE_F26D10.3(hsp-1) CELE_F44E5.4(F44E5.4) CELE_F44E5.5(F44E5.5)
BMY: Bm1_43675
SHX: MS3_11411
DGT: 114517503
HMG: 100203215 100203304(hsp70)
ATH: AT1G16030(Hsp70b) AT1G56410(ERD2) AT3G09440 AT3G12580(HSP70) AT4G24280(cpHsc70-1) AT5G02490(Hsp70-2) AT5G02500(HSC70-1) AT5G49910(cpHsc70-2)
LJA: Lj0g3v0048139.1(Lj0g3v0048139.1) Lj0g3v0059009.1(Lj0g3v0059009.1) Lj0g3v0059079.1(Lj0g3v0059079.1) Lj0g3v0059099.1(Lj0g3v0059099.1) Lj0g3v0059109.1(Lj0g3v0059109.1) Lj0g3v0059119.1(Lj0g3v0059119.1) Lj0g3v0081039.1(Lj0g3v0081039.1) Lj0g3v0116859.1(Lj0g3v0116859.1) Lj0g3v0188709.1(Lj0g3v0188709.1) Lj0g3v0197419.1(Lj0g3v0197419.1) Lj0g3v0209669.1(Lj0g3v0209669.1) Lj0g3v0211099.1(Lj0g3v0211099.1) Lj0g3v0211119.1(Lj0g3v0211119.1) Lj0g3v0256479.1(Lj0g3v0256479.1) Lj0g3v0273329.1(Lj0g3v0273329.1) Lj0g3v0273339.2(Lj0g3v0273339.2) Lj0g3v0273359.1(Lj0g3v0273359.1) Lj0g3v0291079.1(Lj0g3v0291079.1) Lj0g3v0318919.1(Lj0g3v0318919.1) Lj1g3v2448130.1(Lj1g3v2448130.1) Lj1g3v2580570.1(Lj1g3v2580570.1) Lj1g3v3137770.1(Lj1g3v3137770.1) Lj1g3v3137780.1(Lj1g3v3137780.1) Lj1g3v3137820.1(Lj1g3v3137820.1) Lj1g3v3137820.2(Lj1g3v3137820.2) Lj1g3v3137820.3(Lj1g3v3137820.3) Lj1g3v3217890.1(Lj1g3v3217890.1) Lj1g3v3218000.2(Lj1g3v3218000.2) Lj1g3v3218140.1(Lj1g3v3218140.1) Lj1g3v3219230.1(Lj1g3v3219230.1) Lj1g3v3219240.1(Lj1g3v3219240.1) Lj1g3v3458490.1(Lj1g3v3458490.1) Lj1g3v3718110.1(Lj1g3v3718110.1) Lj1g3v3718120.2(Lj1g3v3718120.2) Lj1g3v3718120.3(Lj1g3v3718120.3) Lj1g3v3718120.4(Lj1g3v3718120.4) Lj1g3v4550110.1(Lj1g3v4550110.1) Lj1g3v4865370.1(Lj1g3v4865370.1) Lj2g3v0915000.1(Lj2g3v0915000.1) Lj2g3v0915010.1(Lj2g3v0915010.1) Lj2g3v0915010.2(Lj2g3v0915010.2) Lj3g3v2062810.1(Lj3g3v2062810.1) Lj3g3v3188570.1(Lj3g3v3188570.1) Lj4g3v0119610.1(Lj4g3v0119610.1) Lj4g3v0451110.1(Lj4g3v0451110.1) Lj4g3v2000880.1(Lj4g3v2000880.1) Lj6g3v1966850.1(Lj6g3v1966850.1) Lj6g3v1966930.1(Lj6g3v1966930.1) Lj6g3v1966930.2(Lj6g3v1966930.2)
DOSA: Os01t0688900-00(Os01g0688900) Os01t0840100-01(Os01g0840100) Os03t0276500-01(Os03g0276500) Os03t0276800-01(Os03g0276800) Os03t0277300-01(Os03g0277300) Os03t0821100-01(Os03g0821100) Os05t0303000-01(Os05g0303000) Os05t0460000-01(Os05g0460000) Os11t0187500-01(Os11g0187500) Os11t0187600-01(Os11g0187600) Os11t0703900-01(Os11g0703900) Os12t0244100-01(Os12g0244100)
OLU: OSTLU_28169(HSP70A) OSTLU_32019(HSP70G) OSTLU_48839(HSP70B)
SCE: YAL005C(SSA1) YBL075C(SSA3) YDL229W(SSB1) YER103W(SSA4) YLL024C(SSA2) YNL209W(SSB2)
KMX: KLMA_20459(SSA2) KLMA_50592(SSB) KLMA_80367(SSA3)
NCS: NCAS_0A14440(NCAS0A14440) NCAS_0C05760(NCAS0C05760) NCAS_0D00240(NCAS0D00240) NCAS_0E02580(NCAS0E02580) NCAS_0G01560(NCAS0G01560)
NDI: NDAI_0A01600(NDAI0A01600) NDAI_0E04150(NDAI0E04150) NDAI_0F03620(NDAI0F03620) NDAI_0H00350(NDAI0H00350) NDAI_0H03900(NDAI0H03900)
TPF: TPHA_0E00830(TPHA0E00830) TPHA_0K02090(TPHA0K02090) TPHA_0O01770(TPHA0O01770) TPHA_0P01620(TPHA0P01620)
TBL: TBLA_0B00320(TBLA0B00320) TBLA_0D00580(TBLA0D00580) TBLA_0E01600(TBLA0E01600)
TDL: TDEL_0A00840(TDEL0A00840) TDEL_0C01500(TDEL0C01500) TDEL_0F01620(TDEL0F01620)
KAF: KAFR_0A07780(KAFR0A07780) KAFR_0F00250(KAFR0F00250) KAFR_0I01380(KAFR0I01380) KAFR_0K01860(KAFR0K01860)
PIC: PICST_28757(HSP70.4) PICST_28758(HSP70.6) PICST_38489(HSP70.3) PICST_45857(HSP70.2) PICST_79362(HSP70.1) PICST_80761(SSA2.2) PICST_84662(SSA2.1)
SLB: AWJ20_4148(SSA3) AWJ20_898(SSB2)
BNN: FOA43_001012(SSB1) FOA43_002864(SSA2) FOA43_003355(HSA1)
NCR: NCU02075(hsp70-2) NCU09602(hsp70-1)
NTE: NEUTE1DRAFT117606(NEUTE1DRAFT_117606) NEUTE1DRAFT132552(NEUTE1DRAFT_132552)
ANI: AN5129.2
ANG: ANI_1_1254144(An16g09260) ANI_1_2038104(An12g06890) ANI_1_2182064(An07g09990)
PNO: SNOG_04404 SNOG_14322(SNOG_14320 SNOG_14321)
SPO: SPAC13G7.02c(ssa1) SPBC1709.05(sks2) SPCC1739.13(ssa2)
ABP: AGABI1DRAFT111531(AGABI1DRAFT_111531) AGABI1DRAFT43082(AGABI1DRAFT_43082) AGABI1DRAFT82477(AGABI1DRAFT_82477)
ABV: AGABI2DRAFT133986(hspB) AGABI2DRAFT190759(hspA) AGABI2DRAFT79769(AGABI2DRAFT_79769)
EHI: EHI_002560(418.t00001) EHI_021780 EHI_052860(218.t00008) EHI_104330(38.t00041) EHI_113410(7.t00068) EHI_150770(584.t00001) EHI_155490(71.t00020) EHI_180380 EHI_188610 EHI_192440(69.t00034) EHI_192510(69.t00023) EHI_198320(278.t00009) EHI_201260(136.t00006)
PCB: PCHAS_072100(PC000186.01.0)
TAN: TA11610
TPV: TP02_0148
BBO: BBOV_I003440(19.m02281) BBOV_III010010(17.m07869)
CPV: cgd2_20
TGO: TGME49_273760(HSP70)
SMIN: v1.2.008389.t1(symbB.v1.2.008389.t1) v1.2.014797.t1(symbB.v1.2.014797.t1) v1.2.016332.t1(symbB.v1.2.016332.t1) v1.2.025479.t1(symbB.v1.2.025479.t1) v1.2.025480.t1(symbB.v1.2.025480.t1) v1.2.026931.t1(symbB.v1.2.026931.t1) v1.2.026932.t1(symbB.v1.2.026932.t1) v1.2.026932.t2(symbB.v1.2.026932.t2) v1.2.026932.t3(symbB.v1.2.026932.t3) v1.2.026933.t1(symbB.v1.2.026933.t1) v1.2.026933.t2(symbB.v1.2.026933.t2) v1.2.033454.t1(symbB.v1.2.033454.t1) v1.2.033563.t1(symbB.v1.2.033563.t1) v1.2.034398.t1(symbB.v1.2.034398.t1) v1.2.039109.t1(symbB.v1.2.039109.t1) v1.2.041606.t1(symbB.v1.2.041606.t1)
PTI: PHATRDRAFT_54019(HSP70A)
 » show all
Reference
PMID:3931075
  Authors
Hunt C, Morimoto RI
  Title
Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.
  Journal
Proc Natl Acad Sci U S A 82:6455-9 (1985)
DOI:10.1073/pnas.82.19.6455
  Sequence
[hsa:3303 3304]
Reference
  Authors
Mayer MP, Bukau B
  Title
Hsp70 chaperones: cellular functions and molecular mechanism.
  Journal
Cell Mol Life Sci 62:670-84 (2005)
DOI:10.1007/s00018-004-4464-6
Reference
  Authors
Perez-Vargas J, Romero P, Lopez S, Arias CF
  Title
The peptide-binding and ATPase domains of recombinant hsc70 are required to interact with rotavirus and reduce its infectivity.
  Journal
J Virol 80:3322-31 (2006)
DOI:10.1128/JVI.80.7.3322-3331.2006
  Sequence
[hsa:3303 3304]

KEGG   ORTHOLOGY: K09489
Entry
K09489                      KO                                     

Name
HSPA4
Definition
heat shock 70kDa protein 4
Pathway
ko04530  Tight junction
ko04612  Antigen processing and presentation
ko05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K09489  HSPA4; heat shock 70kDa protein 4
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K09489  HSPA4; heat shock 70kDa protein 4
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K09489  HSPA4; heat shock 70kDa protein 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K09489  HSPA4; heat shock 70kDa protein 4
Chaperones and folding catalysts [BR:ko03110]
 Heat shock proteins
  HSP70 / DNAK
   K09489  HSPA4; heat shock 70kDa protein 4
Other DBs
TC: 1.A.33
Genes
HSA: 3308(HSPA4)
PTR: 462060(HSPA4)
PPS: 100984646(HSPA4)
GGO: 101148292(HSPA4)
PON: 100171909(HSPA4)
NLE: 100602925(HSPA4)
MCC: 709585(HSPA4)
MCF: 102136503(HSPA4)
CSAB: 103244532(HSPA4)
RRO: 104659819(HSPA4)
RBB: 108529570(HSPA4)
CJC: 100401198(HSPA4)
SBQ: 101033095(HSPA4)
MMU: 15525(Hspa4)
MCAL: 110306022(Hspa4)
MPAH: 110332423(Hspa4)
RNO: 266759(Hspa4)
MUN: 110548787(Hspa4)
CGE: 100764628(Hspa4)
NGI: 103747038(Hspa4)
HGL: 101710260(Hspa4)
CCAN: 109696610(Hspa4)
OCU: 100338049(HSPA4)
TUP: 102487965(HSPA4)
CFA: 474680(HSPA4)
VVP: 112917065(HSPA4)
AML: 100484576(HSPA4)
UMR: 103663821(HSPA4)
UAH: 113261730(HSPA4)
ORO: 101363647(HSPA4)
ELK: 111140823
FCA: 101097784(HSPA4)
PTG: 102954567(HSPA4)
PPAD: 109250872(HSPA4)
AJU: 106970683(HSPA4)
BTA: 536558(HSPA4)
BOM: 102268032(HSPA4)
BIU: 109562010(HSPA4)
BBUB: 102402194(HSPA4)
CHX: 102172434(HSPA4)
OAS: 101122782(HSPA4)
SSC: 100524853(HSPA4)
CFR: 102518177(HSPA4)
CDK: 105090224(HSPA4)
BACU: 103014136(HSPA4)
LVE: 103072688(HSPA4)
OOR: 101272709(HSPA4)
DLE: 111182434(HSPA4)
PCAD: 102989263(HSPA4)
ECB: 100072809(HSPA4)
EPZ: 103563074(HSPA4)
EAI: 106841004(HSPA4)
MYB: 102249020(HSPA4)
MYD: 102761862(HSPA4)
MNA: 107525401(HSPA4)
HAI: 109382601(HSPA4)
DRO: 112318080(HSPA4)
PALE: 102887790(HSPA4)
RAY: 107497042(HSPA4)
LAV: 100661115(HSPA4)
TMU: 101352142
MDO: 100015971(HSPA4)
SHR: 100915725(HSPA4)
PCW: 110211687(HSPA4)
OAA: 100079141(HSPA4)
GGA: 416339(HSPA4)
MGP: 100550459(HSPA4)
CJO: 107320051(HSPA4)
NMEL: 110405217(HSPA4)
APLA: 101803843(HSPA4)
ACYG: 106032744(HSPA4)
TGU: 100222389(HSPA4)
LSR: 110476391(HSPA4)
SCAN: 103817393(HSPA4)
GFR: 102031326(HSPA4)
FAB: 101816131(HSPA4)
PHI: 102102437(HSPA4)
PMAJ: 107210824(HSPA4)
CCAE: 111935809(HSPA4)
CCW: 104689481(HSPA4)
ETL: 114066949(HSPA4)
FPG: 101915115(HSPA4)
FCH: 102049592(HSPA4)
CLV: 102090142(HSPA4)
EGZ: 104133678(HSPA4)
NNI: 104012020(HSPA4)
ACUN: 113485152(HSPA4)
PADL: 103923136(HSPA4)
AAM: 106487231(HSPA4)
ASN: 102370228(HSPA4)
AMJ: 106736728(HSPA4)
PSS: 102450795(HSPA4)
CMY: 102936364(HSPA4)
CPIC: 101931893(HSPA4)
ACS: 100565489(hspa4)
PVT: 110085747(HSPA4)
PBI: 103049969(HSPA4)
PMUR: 107286834(HSPA4)
TSR: 106543606(HSPA4)
PMUA: 114591229(HSPA4)
GJA: 107125727(HSPA4)
XLA: 398863(hspa4.S) 399222(hspa4.L)
XTR: 394863(hspa4)
NPR: 108794561(HSPA4)
DRE: 334086(hspa4b) 335865(hspa4a)
IPU: 108274676 108279070(HSPA4)
EEE: 113575597(hspa4) 113584052
TRU: 101062258(hspa4) 101062856
LCO: 104917784 104938369(hspa4)
NCC: 104954924(hspa4) 104962644
ONL: 100690112 100703840(hspa4)
OLA: 101166806(hspa4) 101166977
KMR: 108239002(hspa4a) 108240611(hspa4b)
ALIM: 106517906(hspa4) 106523429
AOCE: 111567548(hspa4) 111579555
POV: 109635819 109639619(hspa4)
SDU: 111226648(hspa4) 111234347
BPEC: 110160394 110162899(hspa4)
LCM: 102356229(HSPA4)
CMK: 103189391(hspa4)
RTP: 109933100(hspa4)
BFO: 118419085
CIN: 100176824
APLC: 110988627
SKO: 100376550
PTEP: 107438136
TSP: Tsp_00561
PCAN: 112559578
CRG: 105326385
MYI: 110445781
OBI: 106880018
LAK: 106151763
SHX: MS3_02688
EGL: EGR_06932
NVE: 5522028
DGT: 114528858
AQU: 100634870
ATH: AT1G11660 AT1G79920(Hsp70-15) AT1G79930(HSP91) AT2G32120(HSP70T-2)
LJA: Lj0g3v0341519.1(Lj0g3v0341519.1) Lj0g3v0341519.2(Lj0g3v0341519.2) Lj3g3v0150720.1(Lj3g3v0150720.1) Lj3g3v2282430.1(Lj3g3v2282430.1) Lj6g3v0920460.1(Lj6g3v0920460.1)
DOSA: Os01t0180800-01(Os01g0180800) Os03t0218500-01(Os03g0218500) Os05t0181000-01(Os05g0181000) Os06t0679800-00(Os06g0679800)
CRE: CHLREDRAFT_15589(HSP70E)
VCN: VOLCADRAFT_89839(hsp70E)
APRO: F751_0629
NCR: NCU05269(hsp88)
NTE: NEUTE1DRAFT100057(NEUTE1DRAFT_100057)
MGR: MGG_06065
SSCK: SPSK_00430
MAW: MAC_08627
MAJ: MAA_01100
CMT: CCM_02954
MBE: MBM_06668
ANI: AN1047.2
ANG: ANI_1_758074(An08g05300)
ABE: ARB_01643
TVE: TRV_05733
PTE: PTT_07155
SPO: SPAC110.04c(pss1)
CNE: CNM02070
CNB: CNBM1940
TASA: A1Q1_00703
MRR: Moror_660
ABP: AGABI1DRAFT116477(AGABI1DRAFT_116477)
ABV: AGABI2DRAFT196038(hspE)
MGL: MGL_0201
MRT: MRET_1114
MSYM: MSY001_0570(Mala_s_10)
DDI: DDB_G0290187(hspH)
DFA: DFA_00366(hspH)
EHI: EHI_197860(197.t00013)
PCB: PCHAS_122000(PC000358.01.0)
TAN: TA12100
TPV: TP02_0243
BBO: BBOV_III004240(17.m07382)
CPV: cgd4_3270
SMIN: v1.2.006708.t1(symbB.v1.2.006708.t1)
PTI: PHATRDRAFT_41417(HSP70F)
TPS: THAPSDRAFT_39098(HSP70_1)
 » show all
Reference
  Authors
Mohamed BA, Barakat AZ, Zimmermann WH, Bittner RE, Muhlfeld C, Hunlich M, Engel W, Maier LS, Adham IM
  Title
Targeted disruption of Hspa4 gene leads to cardiac hypertrophy and fibrosis.
  Journal
J Mol Cell Cardiol 53:459-68 (2012)
DOI:10.1016/j.yjmcc.2012.07.014
Reference
PMID:8335910
  Authors
Fathallah DM, Cherif D, Dellagi K, Arnaout MA
  Title
Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5.
  Journal
J Immunol 151:810-3 (1993)
  Sequence
[hsa:3308]

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