KEGG ORTHOLOGY: K03868

ORTHOLOGY: K03868

Entry

K03868                      KO

Symbol

RBX1, ROC1

Name

E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]

Pathway

map03420

Nucleotide excision repair

map04066

HIF-1 signaling pathway

map04110

Cell cycle

map04111

Cell cycle - yeast

map04114

Oocyte meiosis

map04120

Ubiquitin mediated proteolysis

map04141

Protein processing in endoplasmic reticulum

map04310

Wnt signaling pathway

map04341

Hedgehog signaling pathway - fly

map04350

TGF-beta signaling pathway

map04710

Circadian rhythm

map05131

Shigellosis

map05170

Human immunodeficiency virus 1 infection

map05200

Pathways in cancer

map05211

Renal cell carcinoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04120 Ubiquitin mediated proteolysis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09124 Replication and repair
   03420 Nucleotide excision repair
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04341 Hedgehog signaling pathway - fly
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04350 TGF-beta signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04066 HIF-1 signaling pathway
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04111 Cell cycle - yeast
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   04114 Oocyte meiosis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   03400 DNA repair and recombination proteins
    K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.32  cullin-RING-type E3 NEDD8 transferase
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  UBL E3 ligases
   K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
  Multi subunit Ring-finger type E3
   SCF complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul2 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul3 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul4 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul7 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul8 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
   Cul9 complex
    Ring finger protein
     K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1
    TCR (transcription coupled repair) factors
     Cul4-CSA complex
      K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1

Other DBs

COG:

COG5194

GO:

0019788

Genes

HSA:	9978(RBX1)

PTR:	458860(RBX1)

PPS:	100970959 100981636(RBX1)

GGO:	101151577(RBX1)

PON:	100441665(RBX1)

PPYG:

129023107(RBX1)

NLE:	100596079(RBX1)

HMH:	116458544(RBX1)

SSYN:

129467895(RBX1)

MCC:	710252(RBX1)

MCF:	102132483(RBX1)

MNI:	105464390(RBX1)

CSAB:

103223367(RBX1)

CATY:

105572541(RBX1)

PANU:

101025661(RBX1)

TGE:	112633503(RBX1)

MLEU:

105538834(RBX1)

RRO:	104673455(RBX1)

RBB:	108528465(RBX1)

TFN:	117096433(RBX1)

PTEH:

111532697 111548968(RBX1)

CANG:

105527741(RBX1)

CJC:	100391523(RBX1) 103796394

SBQ:	101031903(RBX1)

CIMI:

108290508(RBX1)

ANAN:

105716995 105721831(RBX1)

CSYR:

103260489(RBX1)

MMUR:

105858549(RBX1)

LCAT:

123640318(RBX1)

PCOQ:

105805282(RBX1)

OGA:	100963359(RBX1)

MMU:	56438(Rbx1)

MCAL:

110310464(Rbx1)

MPAH:

110334961(Rbx1)

RNO:	300084(Rbx1)

MCOC:

116076358(Rbx1)

ANU:	117719097(Rbx1)

MUN:	110550435(Rbx1)

CGE:	100762556(Rbx1)

MAUA:

101838028(Rbx1)

PROB:

127225828(Rbx1)

PLEU:

114694298(Rbx1) 114707186

MORG:

121444018 121461000(Rbx1)

MFOT:

126492120 126501446

AAMP:

119823435(Rbx1)

NGI:	103743488(Rbx1)

HGL:	101712475(Rbx1)

CPOC:

100714763(Rbx1)

CCAN:

109686914(Rbx1)

DORD:

105992090(Rbx1)

DSP:	122123619(Rbx1)

PLOP:

125350718 125358037(Rbx1)

NCAR:

124983356

MMMA:

107155854(Rbx1)

OCU:

103352470

OPI:	101519048(RBX1)

TUP:	102468598(RBX1)

GVR:	103585666(RBX1)

CFA:	474494(RBX1)

CLUD:

112667276(RBX1)

VVP:	112934005(RBX1)

VLG:	121491679(RBX1)

NPO:	129511746(RBX1)

UMR:	103674160(RBX1)

UAH:	113241739(RBX1)

UAR:	123780699(RBX1)

ELK:

111157501

LLV:

125106731

MPUF:

101687674(RBX1)

MNP:	132019190(RBX1)

MLK:	131839520(RBX1)

NVS:	122892604(RBX1) 122902420

ORO:	101363104(RBX1)

EJU:	114218392(RBX1)

ZCA:	113911560 113921968(RBX1)

MLX:	117998640(RBX1)

NSU:	110577946(RBX1)

LWW:	102748318(RBX1)

FCA:	101087758(RBX1)

PYU:	121040293(RBX1)

PCOO:

112863270(RBX1)

PBG:	122472803(RBX1)

PVIV:

125170397(RBX1)

LRUF:

124501699

PTG:	102955881(RBX1)

PPAD:

109265611(RBX1)

PUC:

125920366

AJU:

113602716

HHV:	120234320(RBX1) 120234672 120236827

BTA:	518880(RBX1) 780968

BOM:	102272719(RBX1)

BIU:	109559850(RBX1)

BBUB:

102414522(RBX1)

BBIS:

104981171(RBX1)

CHX:	102187112(RBX1) 102188771

OAS:	101109871(RBX1)

BTAX:

128047495(RBX1) 128067535

ODA:	120857602(RBX1)

CCAD:

122423474(RBX1) 122426581 122445122

MBEZ:

129536465(RBX1)

SSC:	110260638(RBX1)

CFR:	102515877(RBX1)

CBAI:

105073197(RBX1)

CDK:	105091911(RBX1)

VPC:	102535913(RBX1)

BACU:

102998295(RBX1)

BMUS:

118888805 118902305(RBX1)

LVE:	103090829(RBX1)

OOR:	101287254(RBX1) 101289349

DLE:	111186303(RBX1)

PCAD:

102989901 112064697 129391324(RBX1)

PSIU:

116749210 116760644(RBX1)

NASI:

112394651(RBX1)

ECB:	100055581(RBX1)

EPZ:	103556120(RBX1)

EAI:	106842455(RBX1)

MYB:	102243164 102243482 102254932 102260998(RBX1)

MYD:	102760790(RBX1)

MMYO:

118650853(RBX1) 118659026 118663966 118663967

MLF:	102431403(RBX1)

MDT:	132216300 132217262 132226912(RBX1) 132234256 132240300

PKL:	118730800(RBX1)

EFUS:

103288833(RBX1)

MNA:	107531277(RBX1)

DRO:	112321770(RBX1)

SHON:

119002280(RBX1)

AJM:	119060371(RBX1)

PDIC:

114513192(RBX1)

PHAS:

123816194(RBX1)

MMF:	118618357 118624414(RBX1)

PPAM:

129077850(RBX1)

HAI:	109392275(RBX1)

RFQ:	117029081(RBX1)

PALE:

102893437(RBX1)

PGIG:

120602973(RBX1)

PVP:	105298053(RBX1)

RAY:	107519712(RBX1)

MJV:	108394317(RBX1)

TOD:	119247226(RBX1)

SARA:

101542238(RBX1) 101554111

SETR:

126006345(RBX1) 126032651

LAV:	100657479(RBX1)

TMU:

101349359

ETF:	101646762(RBX1) 101662489

DNM:	101444027(RBX1)

MDO:	100013521(RBX1)

GAS:	123250747(RBX1)

SHR:	100918404(RBX1)

AFZ:

127538369

PCW:	110205825(RBX1)

TVP:	118852353(RBX1)

OAA:	100076928(RBX1)

GGA:	418001(RBX1)

PCOC:

116233383(RBX1)

MGP:	100543550(RBX1)

CJO:	107312930(RBX1)

TPAI:

128073610(RBX1)

LMUT:

125686379(RBX1)

NMEL:

110392307(RBX1)

APLA:

101796040(RBX1)

ACYG:

106035919(RBX1)

CATA:

118250500(RBX1)

AFUL:

116501779(RBX1)

TGU:	100190092(RBX1)

LSR:	110483089(RBX1)

SCAN:

103813288(RBX1)

PMOA:

120510088(RBX1)

OTC:	121342452(RBX1)

PRUF:

121361199(RBX1)

GFR:	102037823(RBX1)

FAB:	101806409(RBX1)

OMA:	130248223(RBX1)

PHI:	102102832(RBX1)

PMAJ:

107204430(RBX1)

CCAE:

111934630(RBX1)

CCW:	104696532(RBX1)

CBRC:

103618243(RBX1)

ETL:	114058064(RBX1)

ZAB:	102069638(RBX1)

ZLE:	135442487(RBX1)

ACHL:

103803839

SVG:	106856936(RBX1)

MMEA:

130587945(RBX1)

HRT:	120752174(RBX1)

SATI:

136361865(RBX1)

FPG:	101916874(RBX1)

FCH:	102049129(RBX1)

NNT:	104399424(RBX1)

SHAB:

115605825(RBX1)

ACUN:

113488055(RBX1)

TALA:

104364386(RBX1)

ACHC:

115352685(RBX1)

HALD:

104318900(RBX1)

HLE:	104829039(RBX1)

AGEN:

126047828

GCL:

127022521

CSTI:

104549877(RBX1)

PADL:

103915729(RBX1)

AFOR:

103907880(RBX1)

FGA:	104079903(RBX1)

CLV:	102095842(RBX1)

CUCA:

104055502(RBX1)

OHA:	104329873(RBX1)

ACAR:

104519277(RBX1)

CPEA:

104387596(RBX1)

RTD:	128901312(RBX1)

AAM:	106488968(RBX1)

AROW:

112965730(RBX1)

NPD:	112946469(RBX1)

TGT:	104574103(RBX1)

DNE:	112984067(RBX1)

SCAM:

104137962(RBX1)

ASN:	102372162(RBX1)

AMJ:	102571619(RBX1)

CPOO:

109316717(RBX1)

GGN:	109295958(RBX1)

PSS:	102451113(RBX1)

CMY:	102943754(RBX1)

CCAY:

125629578(RBX1)

DCC:	119847713(RBX1)

CPIC:

101936281(RBX1)

TST:	117880076(RBX1)

CABI:

116829058(RBX1)

MRV:	120381008 120384740

ACS:	100566553(rbx1)

ASAO:

132775977(RBX1)

PVT:	110076073(RBX1)

SUND:

121932202(RBX1)

PBI:	103065423(RBX1)

PMUR:

107285413(RBX1)

CTIG:

120304681(RBX1)

TSR:	106537822(RBX1) 106553210

PGUT:

117655425(RBX1)

APRI:

131202643(RBX1)

PTEX:

113433975(RBX1)

NSS:	113432693(RBX1)

VKO:	123036074(RBX1)

PMUA:

114605459(RBX1)

PRAF:

128420865 128422195(RBX1)

ZVI:	118091458(RBX1)

HCG:	128327088(RBX1)

GJA:	107117140(RBX1)

STOW:

125435698(RBX1)

EMC:	129335725(RBX1)

XLA:	108714482(rbx1.L) 108715730(rbx1.S)

XTR:	100379935(rbx1)

NPR:	108788200(RBX1)

RTEM:

120945492(RBX1)

BBUF:

120979112(RBX1)

BGAR:

122943674(RBX1)

MUO:	115460141(RBX1)

GSH:	117355933(RBX1)

DRE:	449846(rbx1)

SRX:	107723609 107748812

SANH:

107672143(rbx1) 107695112

SGH:	107580054 107602336(rbx1)

CCAR:

109076699(rbx1)

CAUA:

113046818 113047604

CGIB:

127945830 127953577

PTET:

122332598(rbx1)

LROH:

127163576(rbx1)

OMC:	131537527(rbx1)

PPRM:

120462132(rbx1)

RKG:	130075990(rbx1)

MAMB:

125273687(rbx1)

CIDE:

127509265

CERY:

137010318(rbx1)

MASI:

127450052 127452336

TROS:

130561726(rbx1)

TDW:	130426882(rbx1)

MANU:

129436478(rbx1)

IPU:	100528272(rbx1) 108279000 108279790

IFU:	128615623(rbx1) 128622163

PHYP:

113524074(rbx1)

SMEO:

124381909(rbx1)

TFD:	113640136(rbx1)

TVC:	132842552(rbx1)

TRN:	134334626(rbx1)

AMEX:

107197156 125799446

CMAO:

118805387(rbx1)

EEE:	113583718(rbx1)

CHAR:

105897984(rbx1)

TRU:	101079814 115248454 115249889 115249890

TFS:	130514717 130514727

TNG:	GSTEN00008999G001

LCO:	104932083(rbx1)

NCC:	104945083(rbx1)

TBEN:

117492884(rbx1)

CGOB:

115012294(rbx1)

PGEO:

117451336(rbx1)

GACU:

117534788(rbx1)

EMAC:

134878110(rbx1)

ELY:	117268068(rbx1)

EFO:	125879233(rbx1)

PLEP:

121956973(rbx1) 121966503

SLUC:

116065292(rbx1)

ECRA:

117958649(rbx1)

ESP:	116702801(rbx1)

PFLV:

114569772(rbx1)

GAT:	120827413(rbx1)

PPUG:

119220154(rbx1)

AFB:	129098657(rbx1)

CLUM:

117735638(rbx1)

PSWI:

130189005(rbx1)

MSAM:

119884920(rbx1)

SCHU:

122868958(rbx1)

CUD:	121529177(rbx1)

ALAT:

119013730(rbx1)

MZE:	101480103(rbx1)

ONL:	100696705(rbx1)

OAU:	116327876(rbx1)

OLA:	101170590(rbx1)

OML:	112146889(rbx1)

CSAI:

133421806(rbx1)

XMA:	102233269(rbx1)

XCO:	114160562(rbx1)

XHE:	116736204(rbx1)

PRET:

103468459(rbx1)

PFOR:

103153424(rbx1)

PLAI:

106961597(rbx1)

PMEI:

106930562(rbx1)

GAF:	122822198(rbx1)

PPRL:

129363787(rbx1)

CVG:	107093096(rbx1)

CTUL:

119799435(rbx1)

GMU:	124863171 124864508

NFU:	107376330(rbx1)

KMR:	108236172(rbx1)

ALIM:

106520678(rbx1)

NWH:	119422119(rbx1)

AOCE:

111570331(rbx1)

MCEP:

124998308(rbx1)

CSEM:

103393328(rbx1)

POV:	109643626(rbx1)

SSEN:

122785647(rbx1)

HHIP:

117766292(rbx1)

HSP:	118122773(rbx1)

PPLT:

128458775(rbx1)

SMAU:

118289065(rbx1)

LCF:

108877581

SDU:	111230345(rbx1)

SLAL:

111647571(rbx1)

XGL:	120783375(rbx1)

HCQ:	109514860(rbx1)

SSCV:

125984196

SBIA:

133514858(rbx1)

PEE:	133414852(rbx1)

PTAO:

133465743(rbx1)

BPEC:

110162377(rbx1)

MALB:

109952664(rbx1)

BSPL:

114860326(rbx1)

SJO:	128378727(rbx1)

SASA:

100136424(rbx1) 106601243(rbx1)

STRU:

115171287 115199956

OTW:	112226161 112247600 112258810

OMY:	100301858(rbx1) 110486413

OGO:	124000287 124015661

ONE:	115104268 115109887

OKI:	109864917 109898526 109898577

OKE:	118365448 118384582

SALP:

111965561 111981970 112072990

SNH:	120034372 120037660

CCLU:

121550972 121569034

ELS:	105025789(rbx1)

SFM:	108926071(rbx1) 108939936 108939944

PKI:	111845210(rbx1) 111853244

AANG:

118216689(rbx1) 118218515

PSPA:

121306188(rbx1)

PSEX:

120536924(rbx1)

LCM:	102352187(RBX1)

CMK:	103189242(rbx1)

RTP:	109921792(rbx1)

CPLA:

122542300(rbx1)

HOC:	132820883 132831298(rbx1)

LERI:

129713871(rbx1)

PMRN:

116951478(RBX1)

LRJ:	133340675(RBX1) 133360292 133360954

BFO:

BBEL:

CIN:

SCLV:

SPU:	115918507 591601

LPIC:

APLC:

ARUN:

AJC:

DME:	Dmel_CG16982(Roc1a) Dmel_CG16988(Roc1b)

DER:	6545155 6555510

DSE:	6610179 6615886

DSI:	Dsimw501_GD11014(Dsim_GD11014) Dsimw501_GD16520(Dsim_GD16520)

DYA:	Dyak_GE16630 Dyak_GE17622 Dyak_GE21084

DAN:	6496786 6500186 6504852

DSR:	110178156 110181408 110181527 110181780

DPO:	4814059 6898356 6901854 6902120

DPE:	6590337 6597670 6599516 6600097

DMN:	108151726 108157979 108158743 108164784

DWI:	124461521 124461729 124461882 124461913 6638168 6642959 6644881 6645940 6652807 6653602

DGR:	6558239 6559441 6562654 6569282

DMO:	Dmoj_GI14277 Dmoj_GI16422 Dmoj_GI16738 Dmoj_GI20142 Dmoj_GI25778

DAZ:	108609727 108613301 108618888 108620113

DNV:	108651181 108655043 108656193 115562720

DHE:	111601088 111603518 111604779 111605125

DVI:	6622041 6626811 6634529 6635721

CCAT:

101452937 101454374

BOD:	106621760 106627011 118679759 118681423

BDR:	105225495 105233202

RZE:	108368697 108368698 108377436 108382225

AOQ:	129239202 129239593

TDA:	119661908 119669149 119671315 119671343 119671347 119672072 119677018 119679884 119680239 119685952 119685953 119687493 119688891 119689574 119689652

MDE:	101897666 101900642 131800338

SCAC:

106096045

LCQ:	111684342 111688763

LSQ:	119604129 119604908

GFS:	119631557 119637363

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109423057 109432379 115260693

ASUA:

134209161 134209169

CQU:	CpipJ_CPIJ012886

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105674184(Roc1a)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124220941 124221539

NFB:	124184195 124184196

NLO:	107219752 107219759

NVG:	124306744 124307051

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_211860

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:	100162035 100162097

DNX:

107162314

AGS:	114120761 114122273 114123391

RMD:	113552893 113556289

ACOO:

126836636 126840653

DVT:

126903840

BTAB:

109044484

DCI:	103511407 103524839 103524844

CLEC:

106666282

HHAL:

106682125(Roc1a)

NLU:

111058671

HVI:

124362577

MQU:

128989782

PHU:	Phum_PHUM087130

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_40730 DAPPUDRAFT_60651 DAPPUDRAFT_65504 DAPPUDRAFT_65506 DAPPUDRAFT_65509

DMK:

116925355

DPZ:	124349781 124349791

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

119099374 119099407 119105838 119105852

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

111619728 111633535 111638739 111640208

CVS:	136982268(Roc1a) 136982293

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_ZK287.5(rbx-1)

CBR:	CBG_19342(Cbr-rbx-1)

CRQ:	GCK72_016980

NAI:	NECAME_02269

BMY:	BM_BM14000(Bma-rbx-1)

LOA:	LOAG_03239

HRO:	HELRODRAFT_86393

LGI:	LOTGIDRAFT_206883

PCAN:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:	111125628 111125715

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

OVI:	T265_11722

EGL:	EGR_00753 EGR_04378

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_50330

AQU:

100636037

ATH:	AT3G42830 AT5G20570(RBX1)

ALY:

9308017

CRB:	17881315 17886885

CSAT:

104706402 104710838 104736126 104770432 104780213 104790623

EUS:	EUTSA_v10015047mg

BRP:	103845664 103851357 103856451

BNA:	106371726 106385158 106408993 106425686 111213972

BOE:	106316076 106325067 106332287

RSZ:	108817515 108827876 108846167 130509350

THJ:	104808880 104811002 104815338 104826593

CPAP:

110817690

CIT:	102613162 102622192

CIC:	CICLE_v10009952mg CICLE_v10026815mg

PVY:	116120238 116126404

MINC:

123193858 123200043

TCC:

18588272

GRA:	105767665 105792942 105795701

GHI:	107903283 107929974 107932188 107932799 107960807 121204775

GAB:	108468083 108469121 108488019

HSYR:

120114829 120149883 120156633 120167838 120179762 120193390 120211863 120218694

DZI:	111274703 111286458 111299190 111303054

EGR:	104436408 104437993 104439002

GMX:	100500045 100526919 100789570 100798515

GSJ:	114374500 114378027 114378451 114397039 114417297

PVU:	PHAVU_005G114500g PHAVU_011G105100g

VRA:	106754365 106761091 106761707

VAR:	108333295 108338955

VUN:	114168583 114183876

VUM:	124820988 124829759 124829763

CCAJ:

109790424 109806089

APRC:

113855424 113858391

MTR:	11413962 25492127

TPRA:

123899636 123899965 123920291

CAM:	101496300 101503002

PSAT:

127086751 127105727

VVO:	131601747 131626399 131629058

LJA:	130747013 130749032 130749219

ADU:	107462077 107477744 127744049

AIP:	107613945 107624456 107629957

AHF:	112707013 112737543 112771395 112789617

LANG:

109325667 109352320 109353407

PCIN:

129309176 129320352

QSA:	O6P43_002658 O6P43_018413 O6P43_022498 O6P43_027535

FVE:	101301042 101302106 101307444

RCN:	112174210 112179375 112196401 112199925

PPER:

18785603 18786902

PMUM:

103331948 103331952

PAVI:

110746319 110748081 110769275

PDUL:

117617435 117619981

MDM:	103405253 103439121 103450248

MSYL:

126613785 126613786 126628536

PXB:	103942118 103964642

ZJU:

107423885

MNT:

21410023

CSAV:

115707585

CSV:	101209538 101209687

CMO:	103492371 103498857

BHJ:	120071482 120079716

MCHA:

111016444 111021926

CMAX:

111465785 111467761 111485682

CMOS:

111440096 111444049 111461500

CPEP:

111779645 111793107 111798730

RCU:	8259356 8281168

MEAN:

126667731 126667732 126683098

JCU:	105631381 105637971

HBR:	110634308 110639647 110664598

MESC:

110612954 110626830

POP:	18094715 18100330 7471662

PEU:	105133432 105133967

PALZ:

118034841 118037983 118048083

JRE:	108981134 109009026

CILL:

122304274 122307828

CAVE:

132166206 132166306

QSU:	111993014 112001674

QLO:	115969583 115988613

TWL:	119982225 119992954 120005634

VVI:	100246271 100259489

VRI:	117921577 117925760

SLY:	101249890 101259644

SPEN:

107005489 107021447

SOT:	102583049 102595356 107059797

SSTN:

125857671 125862246 125872505

SDUL:

129871323 129899417

CANN:

107840900 107861671 107876064

LBB:	132633526 132636921 132645335

NTA:	107759896 107776199 107780326 107784644 107824015 107829306

NSY:	104214032 104219570 104236463

NTO:	104092250 104104527 104120680

NAU:	109217886 109221000 109225596 109239640

INI:	109147674 109158438 109186622

ITR:	115999746 116012189 116019189

SIND:

105161929 105173683

OEU:	111379972 111384856 111411455

EGT:	105968134 105970859

SSPL:

121746682 121750403 121783554 121786269 121793382 121801447

SMIL:

130987662 131021449 131021462

SHIS:

125186881 125192207 125209534

APAN:

127239533 127264161

HAN:	110880261 110893699 110897767 110916508

ECAD:

122588767 122588803 122607398

LSV:	111882147 111892622 111902717

CCAV:

112509462 112511044 112516390

DCR:	108193846 108211059 108219676 108224330

CSIN:

114302496 114302498

RVL:	131311724 131320017 131325324

AEW:	130756745 130761930 130782600 130784420 130796308

BVG:	104883468 104899743

SOE:	110798000 110804025

CQI:	110682960 110684393 110688077 110733846

ATRI:

130813766 130815046 130827373

MOF:	131157457 131165092

NNU:

104600540

MING:

122076653 122083431

TSS:	122640521 122641411 122648264 122653778 122658402 122663617 122667975

PSOM:

113293923 113326900 113327705 113339765

OSA:	4326152 4330476

OBR:	102707436 102714616

OGL:	127762121 127775911

BDI:	100826136 100841533

ATS:	109737146 109777151

TDC:	119266566 119274241 119317601 119323775

TAES:

123068146 123128144 123137940 123145238 123172046 123172497

TUA:	125514298 125542236

LPER:

127306479 127341399

LRD:	124661924 124666909 124688142

SBI:	8073850 8079092

ZMA:	100192928 103634739 103649912

MFLO:

136451801 136457938 136464298

SITA:

101761659 101778950

SVS:	117835140 117856011

PVIR:

120649760 120656974 120676393 120706260

PHAI:

112879972 112893014

PDA:	103701991 103711519 120113304

EGU:	105056281 105058733

MUS:	103968770 103977230 103981809 103987360

ZOF:	121967126 121981914 121985754 122010237 122017693 122052315

DCT:	110096489 110100420

PEQ:

110019661

AOF:	109828983 109844953

MSIN:

131227046 131251730

NCOL:

116259708 116262899

ATR:	105421056 18439492

SMO:	SELMODRAFT_269625 SELMODRAFT_269937

PPP:	112284365 112288983 112295784

CRE:	CHLRE_12g543450v5

VCN:	VOLCADRAFT_75918

MNG:

MNEG_4176

CSL:	COCSUDRAFT_21809

APRO:

F751_6626

OLU:	OSTLU_119493(rbx1)

OTA:	OT_ostta02g00480

BPG:	Bathy07g04140

MIS:	MICPUN_113936(RBX1)

MPP:	MICPUCDRAFT_25062

CME:	CYME_CMQ353C

GSL:	Gasu_48170

CCP:	CHC_T00009192001

SCE:	YOL133W(HRT1)

SEUB:

DI49_2274

SPAO:

SPAR_O00240

AGO:	AGOS_ADL181W

ERC:

Ecym_2029

KLA:	KLLA0_E07151g

KMX:	KLMA_70161(HRT1)

LTH:	KLTH0F19228g

VPO:	Kpol_1014p16

ZRO:	ZYRO0C03058g

CGR:	9487983(RBX1)

NCS:	NCAS_0C04480(NCAS0C04480)

NDI:	NDAI_0G03860(NDAI0G03860)

TPF:	TPHA_0P01470(TPHA0P01470)

TBL:	TBLA_0B08710(TBLA0B08710)

TGB:	HG536_0E02510

TDL:	TDEL_0A00470(TDEL0A00470)

KAF:	KAFR_0C01780(KAFR0C01780)

KNG:	KNAG_0A01280(KNAG0A01280)

ZMK:	HG535_0F01980

SLUD:

SCDLUD_005007

DHA:	DEHA2F17666g

PIC:	PICST_37145(HRT1)

SPAA:

SPAPADRAFT_61897

LEL:	PVL30_002035(HRT1)

CAL:	CAALFM_C302450WA(HRT1)

CTP:	CTRG_02424

COT:	CORT_0B04130

CDU:	CD36_82410

CTEN:

18245613(HRT1)

CLU:	CLUG_04212

CLUS:

A9F13_04g03124

CAUR:

CJI96_0004926

PPA:	PAS_chr4_0436

PKZ:	C5L36_0C07065

BNN:	FOA43_001196

BBRX:

BRETT_002341

OPA:	HPODL_05342

YLI:	2906622(YALI2_C00737g)

NTE:	NEUTE1DRAFT116888(NEUTE1DRAFT_116888)

SMP:	10803180(SMAC4_07095)

PAN:	PODANSg5275

PBEL:

QC761_708750(HRT1)

PPSD:

QC762_708750(HRT1)

PPSP:

QC763_708750(HRT1)

PPSA:

QC764_708750(HRT1)

MTM:	MYCTH_2304045

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_1639

SSCK:

SPSK_02774

FGR:	FGSG_02497

FPU:	FPSE_08616

FPOA:

FPOAC1_002619(RBX1)

FVN:	FVRRES_02914

FVR:	FVEG_09167

FOX:	FOXG_10518

NHE:	NECHADRAFT_42915

FFC:	NCS54_00847500

FKR:	NCS57_00890400

FMU:	J7337_005231(RBX1)

TRE:	TRIREDRAFT_121950

TRR:	M419DRAFT_104643

TATV:

25780966(TrAtP1_009786)

TASP:

36618731(ROC1A)

MAW:	19246207(HRT1)

MAJ:

MAA_00593

MBRN:

90967816(rbx1)

PCHM:

VFPPC_14152

CMT:

CCM_05836

AMUS:

LMH87_008205

PLJ:	90642691(PLICBS_002297)

PTKZ:

JDV02_002716(HRT1)

VAL:	VDBG_08639

VDA:	VDAG_06301

CFJ:	CFIO01_11879

CLUP:

CLUP02_03553

CHIG:

CH63R_02620

SAPO:

SAPIO_CDS3010

ELA:	UCREL1_3121

PFY:	PFICI_12609

SSL:	SS1G_00027

BFU:	BCIN_03g07500(Bchrt1)

MBE:

MBM_08230

PSCO:

LY89DRAFT_688943

GLZ:	GLAREA_01075

ANI:	ANIA_08844

AFM:	AFUA_5G05790

ACT:	ACLA_009060

NFI:	NFIA_037330

AOR:	AO090009000684

ANG:	An17g02100

AFV:	AFLA_010686

ALUC:

AKAW2_70780S(RBX1)

ACHE:

ACHE_11205A(RBX1)

APUU:

APUU_70423A(RBX1)

PCS:	N7525_008545

PDP:	PDIP_22460

POU:	POX_e06318

TMF:	EYB26_004703

TRG:	TRUGW13939_07977

CIM:	CIMG_06244

CPW:	CPC735_027760

URE:	UREG_04145

ABE:

ARB_07022

TVE:

TRV_07648

PBL:	PAAG_07371

PBN:	PADG_05868

AJE:	HCAG_03036

BGH:	BDBG_08548

PNO:	SNOG_09105

PTE:

PTT_16968

PTRR:

6339032(PtrM4_013440)

BZE:	COCCADRAFT_95811

BSC:	COCSADRAFT_82242

BOR:	COCMIDRAFT_103083

AALT:

CC77DRAFT_1049904

ARAB:

EKO05_0003090

ZTR:	MYCGRDRAFT_46230

PFJ:	MYCFIDRAFT_88404

FFU:	CLAFUR5_07092

CBET:

CB0940_09347

BCOM:

BAUCODRAFT_106019

NPA:	UCRNP2_3000

TML:	GSTUM_00002417001

SPO:	2541897(rbx1)

SOM:	SOMG_01994(rbx1)

CNE:

CNB03140

CNB:

CNBB2560

CNG:	CNAG_03823

CGI:	CGB_A3220W

CDEU:

CNBG_1541

CDEP:

91086181(L203_101969)

KMG:	30164900(I203_108193)

KNE:	92177641(IAR55_000381)

TMS:	TREMEDRAFT_30658

CCAC:

CcaHIS019_0203440(HRT1)

TVS:	TRAVEDRAFT_31548

DSQ:	DICSQDRAFT_136248

PCO:	PHACADRAFT_253837

SHS:	STEHIDRAFT_96405

HIR:	HETIRDRAFT_441743

PSQ:	PUNSTDRAFT_80891

ADL:	AURDEDRAFT_83065

FME:	FOMMEDRAFT_126450

GTR:	GLOTRDRAFT_101369

RSX:	RhiXN_10954

LBC:	LACBIDRAFT_317013

CCI:	CC1G_08674

ABP:	AGABI1DRAFT130185(AGABI1DRAFT_130185)

ABV:	AGABI2DRAFT139777(AGABI2DRAFT_139777)

PCUB:

JR316_0006035 JR316_0013262

MRR:	Moror_7592

E1B28_013366(RBX1)

SCM:	SCHCO_02628431(SCHCODRAFT_02628431)

CPUT:

CONPUDRAFT_106740

SLA:	SERLADRAFT_385744

WSE:	WALSEDRAFT_27573

WIC:	J056_004250

UMA:	UMAG_10917

PFP:	PFL1_04680

SGRA:

EX895_002756

MGL:

MGL_0788

MRT:

MRET_0028

PGR:	PGTG_10430 PGTG_18192

PTRC:

PtA15_6A509 PtA15_8A735

PSTR:

Pst134EA_002618

MLR:	MELLADRAFT_106109

ECU:	ECU01_1095

EIN:	Eint_011010

EHE:	EHEL_010980

ERO:	EROM_010900

NCE:	NCER_101168

VNX:	VNE69_02195

RIE:	OCT59_020748

MBR:	MONBRDRAFT_18418

SRE:	PTSG_04800

DDI:	DDB_G0287629(rbx1)

DPP:	DICPUDRAFT_88388

EHI:	EHI_151630(2.t00108)

EDI:	EDI_254030

EIV:	EIN_381390 EIN_381400

ACAN:

ACA1_368020

PFA:	PF3D7_0319100

PFD:	PFDG_02979

PFH:	PFHG_00876

PREI:

PRSY57_0318400

PGAB:

PGSY75_0319100

PLAG:

39740038(PADL01_0318000)

PYO:	PY17X_0809400

PCB:	PCHAS_0806500

PBE:	PBANKA_0806200

PVV:	PVVCY_1000790

PKN:	PKNH_0822400

PVX:	PVX_095280

PCY:	PCYB_083070

PMAL:

PMUG01_08037000(RBX1)

PBRS:

92370500(MKS88_002412)

PREL:

PRELSG_0819000(RBX1)

PCOT:

PCOAH_00021320

TAN:

TA10565

TPV:

TP04_0669

TOT:	TOT_040000249

BBO:	BBOV_III007590

BMIC:

BmR1_04g06125

BBIG:

BBBOND_0306580

CPV:

cgd8_930

CHO:	Chro.80112

TGO:	TGME49_213690

BBES:

BESB_066840

TET:	TTHERM_00313710

PTM:	GSPATT00005494001 GSPATT00011131001 GSPATT00021114001 GSPATT00023020001 GSPATT00024170001 GSPATT00030724001

PTI:	PHATRDRAFT_39090(Rbx1)

FCY:	FRACYDRAFT_206499

TPS:	THAPSDRAFT_40817

NGD:	NGA_0441600(RBX1)

AAF:	AURANDRAFT_22764 AURANDRAFT_8889

PIF:	PITG_01524

PSOJ:

PHYSODRAFT_285454

SPAR:

SPRG_11654

EHX:	EMIHUDRAFT_358602 EMIHUDRAFT_49116 EMIHUDRAFT_50030

GTT:	GUITHDRAFT_86348

TBR:	Tb10.70.6035

TBG:	TbgDal_V5200 TbgDal_X2190 TbgDal_X9640

TCR:	503965.20 506495.9

LMA:	LMJF_21_0023 LMJF_24_1610

LIF:	LINJ_21_0040 LINJ_24_1680

LDO:	LDBPK_210040 LDBPK_241680

LMI:	LMXM_21_0023 LMXM_24_1610

LMAT:

92514592(LSCM1_04578) 92515105(LSCM1_05120)

LBZ:	LBRM_21_0040 LBRM_24_1670

LPAN:

LPMP_210030 LPMP_241580

LOI:	92361329(LSCM4_05455) 92361576(LSCM4_05710)

NGR:	NAEGRDRAFT_5552

TVA:	TVAG_2v0582920 TVAG_2v1003330 TVAG_2v1003460

» show all

Reference

PMID:10213691

Authors

Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG Jr, Elledge SJ, Conaway RC, Harper JW, Conaway JW

Title

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

Journal

Science 284:657-61 (1999)
DOI:10.1126/science.284.5414.657

Sequence

[sce:YOL133W]

Reference

PMID:10579999

Authors

Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW

Title

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.

Journal

Genes Dev 13:2928-33 (1999)
DOI:10.1101/gad.13.22.2928

Sequence

[hsa:9978] [sce:YOL133W]

Reference

PMID:11027288

Authors

Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y

Title

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.

Journal

Mol Cell Biol 20:8185-97 (2000)
DOI:10.1128/mcb.20.21.8185-8197.2000

All links

Ontology (6)   
   KEGG BRITE (4)   
   GO (1)   
   COG (1)   
Pathway (30)   
   KEGG PATHWAY (30)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (8676)   
   KEGG GENES (1490)   
   KEGG MGENES (93)   
   RefGene (7084)   
   OC (9)   
Literature (3)   
   PubMed (3)   
All databases (8716)   

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