KEGG ORTHOLOGY: K03875

ORTHOLOGY: K03875

Entry

K03875                      KO

Symbol

SKP2, FBXL1

Name

F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)

Pathway

map04068

FoxO signaling pathway

map04110

Cell cycle

map04120

Ubiquitin mediated proteolysis

map04150

mTOR signaling pathway

map05169

Epstein-Barr virus infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05222

Small cell lung cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
   04150 mTOR signaling pathway
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
   05203 Viral carcinogenesis
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Target recognizing subunit (F-box)
     K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)

Genes

HSA:	6502(SKP2)

PTR:	471570(SKP2)

PPS:	100978721(SKP2)

GGO:	101134461(SKP2)

PON:	100432371(SKP2)

PPYG:

129036105(SKP2)

NLE:	100586655(SKP2)

HMH:	116456910(SKP2)

SSYN:

129464667 129464923

MCC:	700617(SKP2)

MCF:	102114882(SKP2)

MTHB:

126957088

MNI:	105473080(SKP2)

CSAB:

103215131(SKP2)

CATY:

105583426(SKP2)

PANU:

101000264(SKP2)

TGE:	112625831(SKP2)

MLEU:

105555423(SKP2)

RRO:	104662024(SKP2)

RBB:	108535053(SKP2)

TFN:	117065023(SKP2)

PTEH:

111545519(SKP2)

CANG:

105513491(SKP2)

CJC:	100393248(SKP2)

SBQ:

101041621

CIMI:

108317630(SKP2)

ANAN:

105722483(SKP2)

CSYR:

103251986(SKP2)

MMUR:

105855459(SKP2)

LCAT:

123648646(SKP2)

PCOQ:

105814809(SKP2)

OGA:	100942708(SKP2)

MMU:	27401(Skp2)

MCAL:

110310405(Skp2)

MPAH:

110328844(Skp2)

RNO:	294790(Skp2)

MCOC:

116083772(Skp2)

ANU:	117724054(Skp2)

MUN:	110566051(Skp2)

CGE:	100771396(Skp2)

MAUA:

101837348(Skp2)

PROB:

127220633(Skp2)

PLEU:

114681382 114697360(Skp2)

MORG:

121433099(Skp2) 121439825 121445087 121445657 121445658

MFOT:

126488277 126499685

AAMP:

119805439 119805441 119805442 119809590(Skp2)

NGI:	103741317(Skp2)

HGL:	101706248(Skp2)

CPOC:

100720705(Skp2)

CCAN:

109702695(Skp2)

DORD:

105987402(Skp2)

DSP:	122117008(Skp2)

PLOP:

125367687(Skp2)

NCAR:

124986905

MMMA:

107151118(Skp2)

OCU:	100338447 100342452

OPI:	101531086(SKP2)

TUP:	102497164(SKP2)

GVR:	103597559(SKP2)

CFA:	489228(SKP2)

CLUD:

112652849(SKP2)

VVP:	112933526(SKP2)

VLG:	121488336(SKP2)

NPO:	129509822(SKP2)

AML:	100480437(SKP2)

UMR:	103664708(SKP2)

UAH:	113260895(SKP2)

UAR:	123785481(SKP2)

ELK:

111140933

LLV:

125099857

MPUF:

101682622(SKP2)

MNP:	132028248(SKP2)

MLK:	131831657(SKP2)

NVS:	122895358(SKP2)

ORO:	101383205(SKP2)

EJU:	114204772(SKP2)

ZCA:	113928995(SKP2)

MLX:	118006346 118006475

NSU:	110586053(SKP2)

LWW:

102736340

FCA:	101099275(SKP2)

PYU:	121043524(SKP2)

PCOO:

112861348(SKP2)

PBG:	122494612(SKP2)

PVIV:

125157110(SKP2)

LRUF:

124522217

PTG:	102964396(SKP2)

PPAD:

109260099(SKP2)

PUC:

125934645

AJU:

106979642

HHV:	120244162(SKP2)

BTA:	519018(SKP2) 785617

BOM:	102269700(SKP2) 102277531

BIU:	109574865(SKP2) 109579088

BBUB:

102395935(SKP2)

BBIS:

104998552(SKP2)

CHX:	102172762(SKP2)

OAS:	101109483(SKP2)

BTAX:

128059172 128066055(SKP2)

ODA:	120879342(SKP2)

CCAD:

122454407(SKP2)

MBEZ:

129550007 129553317(SKP2)

SSC:	100329128(SKP2)

CFR:	102523584(SKP2)

CBAI:

105069411(SKP2)

CDK:	105086996(SKP2)

VPC:	102541169(SKP2)

BACU:

103007736(SKP2)

BMUS:

118892325(SKP2)

LVE:	103090160(SKP2)

OOR:	101274005(SKP2)

DLE:	111187525(SKP2)

PCAD:

102973239 102991021

PSIU:

116752049(SKP2)

NASI:

112406027(SKP2)

ECB:	100053697(SKP2)

EPZ:

103563536

EAI:	106824722(SKP2)

MYB:	102262715(SKP2)

MYD:	102770564(SKP2)

MMYO:

118655860(SKP2)

MLF:	102429293(SKP2)

MDT:	132233761(SKP2)

PKL:	118703716(SKP2)

EFUS:

103298086(SKP2)

MNA:	107546230(SKP2)

DRO:	112321074(SKP2)

SHON:

118998776(SKP2)

AJM:	119037019(SKP2)

PDIC:

114497743(SKP2)

PHAS:

123824539(SKP2)

MMF:	118641733(SKP2)

PPAM:

129079051(SKP2)

HAI:	109387065(SKP2)

RFQ:	117025370(SKP2)

PALE:

102880695(SKP2)

PGIG:

120586194(SKP2)

PVP:	105307445(SKP2)

RAY:	107509711(SKP2)

TOD:	119261442(SKP2)

SARA:

101554118(SKP2)

SETR:

126001810(SKP2)

LAV:	100676976(SKP2)

TMU:

101348198

ETF:	101646103(SKP2)

DNM:	101439951(SKP2)

MDO:	100020421(SKP2)

GAS:	123231512(SKP2)

SHR:	100915218(SKP2)

AFZ:

127556614

PCW:	110214774(SKP2)

TVP:	118829143(SKP2)

OAA:	103166602(SKP2)

GGA:	427437(SKP2)

PCOC:

116238633(SKP2)

MGP:	100542923(SKP2)

CJO:	107305844(SKP2)

TPAI:

128074559(SKP2)

LMUT:

125687015(SKP2)

NMEL:

110389514(SKP2)

APLA:

101802477(SKP2)

ACYG:

106036387(SKP2)

CATA:

118256634(SKP2)

AFUL:

116500511(SKP2)

TGU:	100217547(SKP2)

LSR:	110482530(SKP2)

SCAN:

103821008

PMOA:

120502538(SKP2)

OTC:	121343558(SKP2)

PRUF:

121352838(SKP2)

GFR:	102037500(SKP2)

FAB:	101810388(SKP2)

OMA:	130264793(SKP2)

PHI:	102109076(SKP2)

PMAJ:

107216438(SKP2)

CCAE:

111940976(SKP2)

CCW:	104686606(SKP2)

CBRC:

103612925(SKP2)

ETL:	114055031(SKP2)

ZAB:	102063901(SKP2)

ZLE:	135459459(SKP2)

ACHL:

103808307(SKP2)

SVG:	106852735(SKP2)

MMEA:

130572771(SKP2)

HRT:	120765927(SKP2)

SATI:

136373898(SKP2)

FPG:	101911609(SKP2)

FCH:	102053148(SKP2)

CCRI:

104167997

NNT:	104402803(SKP2)

SHAB:

115619493(SKP2)

ACUN:

113489833(SKP2)

TALA:

104365382(SKP2)

ACHC:

115336928(SKP2)

HALD:

104315675(SKP2)

HLE:	104830611(SKP2)

AGEN:

126036152

GCL:

127027325

LDI:	104354836(SKP2)

MNB:	103776949(SKP2)

DPUB:

104303135(SKP2)

AVIT:

104271097(SKP2)

BRHI:

104489774(SKP2)

EGZ:	104133851(SKP2)

NNI:	104018639(SKP2)

PCRI:

104030830(SKP2)

PCAO:

104050010

PADL:

103921478(SKP2)

AFOR:

103903877(SKP2)

FGA:	104069982(SKP2)

GSTE:

104251056(SKP2)

CLV:	102084967(SKP2)

MUI:	104545905(SKP2)

PGUU:

104461929

PLET:

104624397(SKP2)

EHS:	104503068(SKP2)

CMAC:

104486391(SKP2)

CUCA:

104063836(SKP2)

TEO:

104369760

BREG:

104640402(SKP2)

OHA:	104337674(SKP2)

ACAR:

104526443(SKP2)

CPEA:

104398599(SKP2)

CVF:	104294985(SKP2)

RTD:	128902479(SKP2)

AAM:	106499538(SKP2)

AROW:

112976200(SKP2)

NPD:	112946216(SKP2)

TGT:

104570690

DNE:	112982167(SKP2)

SCAM:

104147787(SKP2)

ASN:	102367894(SKP2)

AMJ:	102558881(SKP2)

CPOO:

109307834(SKP2)

GGN:	109297897(SKP2)

PSS:	102445640(SKP2)

CMY:	102933431(SKP2)

CCAY:

125637254(SKP2)

DCC:	119855800(SKP2)

CPIC:

101935689(SKP2)

TST:	117879165(SKP2)

CABI:

116824574(SKP2)

MRV:	120408460(SKP2)

ACS:	100564206(skp2)

ASAO:

132766927(SKP2)

PVT:	110080059(SKP2)

SUND:

121922239(SKP2)

PBI:	103054864(SKP2)

PMUR:

107297968(SKP2)

CTIG:

120310021(SKP2)

TSR:	106557164(SKP2)

PGUT:

117679988(SKP2)

APRI:

131191714(SKP2)

PTEX:

113446198(SKP2)

NSS:	113411381(SKP2)

VKO:	123024013(SKP2)

PRAF:

128423312(SKP2)

ZVI:	118077117(SKP2)

HCG:	128344661(SKP2)

GJA:	107108086(SKP2)

STOW:

125436100(SKP2)

EMC:	129334299(SKP2)

XLA:	734901(skp2.L)

XTR:	100216169(skp2)

NPR:	108792651(SKP2)

RTEM:

120927590(SKP2)

BBUF:

120992178(SKP2)

BGAR:

122939079(SKP2)

MUO:	115462940(SKP2)

GSH:	117352642(SKP2)

DRE:	563708(skp2)

SRX:	107706432 107718976

SANH:

107681151 107703541

SGH:	107548167 107551629

CCAR:

109045264 109076410

CAUA:

113038625 113064272

CGIB:

127941621 127986261

PTET:

122326673(skp2)

LROH:

127152634(skp2)

OMC:	131528753(skp2)

PPRM:

120494628(skp2)

RKG:	130096485(skp2)

MAMB:

125253496(skp2)

CIDE:

127503905

CERY:

137012193(skp2)

MASI:

127428594 127431103

TROS:

130570465(skp2)

TDW:	130408151(skp2)

MANU:

129424419(skp2)

IPU:

108279378

IFU:	128622770(skp2)

PHYP:

113541502(skp2)

SMEO:

124397633(skp2)

TFD:	113634912(skp2)

TVC:	132860459(skp2)

TRN:	134330739(skp2)

AMEX:

103047278(skp2)

CMAO:

118819980(skp2)

EEE:	113574196(skp2)

CHAR:

105893344(skp2)

TRU:	101066648(skp2)

TFS:	130517534(skp2)

LCO:	104938172(skp2)

TBEN:

117478778(skp2)

CGOB:

115006030(skp2)

PGEO:

117444333(skp2) 117444335

GACU:

117542904(skp2)

EMAC:

134868420(skp2)

ELY:	117269393(skp2)

EFO:	125905915(skp2)

PLEP:

121959762(skp2)

SLUC:

116041399(skp2)

ECRA:

117959233(skp2)

ESP:	116704054(skp2)

PFLV:

114571071(skp2)

GAT:

120831654

PPUG:

119226275(skp2)

AFB:	129102453(skp2)

CLUM:

117740939(skp2)

PSWI:

130205111(skp2)

MSAM:

119914397(skp2)

SCHU:

122865389(skp2)

CUD:	121525283(skp2)

ALAT:

119029939(skp2)

MZE:	101475050(skp2)

ONL:	100695272(skp2)

OAU:	116315777(skp2)

OLA:	101156183(skp2)

OML:	112163437(skp2)

CSAI:

133454887(skp2)

XMA:	102229286(skp2)

XCO:	114150144(skp2)

XHE:	116723969(skp2)

PRET:

103474062(skp2)

PFOR:

103131313(skp2)

PLAI:

106956194(skp2)

PMEI:

106927045(skp2)

GAF:	122847133(skp2)

PPRL:

129354289

CVG:	107093937(skp2)

CTUL:

119780548(skp2)

GMU:	124872139(skp2)

NFU:	107375004(skp2)

KMR:	108228591(skp2)

ALIM:

106531672(skp2)

NWH:	119425005(skp2)

AOCE:

111574103(skp2)

MCEP:

124996351(skp2)

CSEM:

103389192 103389199

POV:	109647460(skp2)

SSEN:

122758576(skp2)

HHIP:

117771425(skp2)

HSP:	118098072(skp2)

PPLT:

128424785(skp2)

SMAU:

118284506(skp2)

LCF:	108900731(skp2)

SDU:	111221206(skp2)

SLAL:

111648076(skp2)

XGL:	120806862(skp2)

HCQ:	109529111(skp2)

SSCV:

125979846

SBIA:

133490576(skp2)

PEE:	133401852 133413965(skp2)

PTAO:

133480038 133480041 133480043 133489974(skp2)

BPEC:

110161888(skp2)

MALB:

109960759(skp2)

BSPL:

114866419(skp2)

SJO:	128380407(skp2)

SASA:

106563829 106568170

STRU:

115149232(skp2)

OTW:

112257530

OMY:

110537145

OGO:

123999595

ONE:	115105866(skp2)

OKI:	109892486(skp2)

OKE:	118391435(skp2)

SALP:

111961421 111981396(skp2)

SNH:	120025561(skp2) 120044230

CCLU:

121573859 121582186

ELS:	105025175(skp2)

SFM:	108933818(skp2)

PKI:	111842164(skp2)

AANG:

118212239(skp2)

LOC:	102683784(skp2)

PSPA:

121304766 121318314

ARUT:

117409303 117421557(skp2)

PSEX:

120527290(skp2)

LCM:	102356499(SKP2)

RTP:	109923386(skp2)

CPLA:

122556303(skp2)

HOC:	132826348(skp2)

LERI:

129694395(skp2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

SKO:

DME:	Dmel_CG9772(Skp2)

DER:

6552112

DSE:

6613812

DSI:	Dsimw501_GD19685(Dsim_GD19685)

DYA:	Dyak_GE25359

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22887

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101893441 131801543

SCAC:

106080639

LCQ:

111690972

LSQ:	119609018 119614484 119614996

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ003639

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105678405(Skp2)

PGC:

OBO:

PCF:

PFUC:

VPS:	122631315 122631319

VCRB:

124426014 124426016

VVE:	124951699 124951703

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

122847388 122847889 122848867 122855153 122855394 122860464

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:	115879259 115884331

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212958

BANY:

MJU:

VCD:

MCIX:

PMAC:

PPOT:

PXU:	106122494 106126037

PRAP:

ZCE:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:	100160074 100574783

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM040260

FOC:	113204821 113205756 113206717 113207325 113209149 113211511 113215554

TPAL:

117640645 117644960 117646904 117647115 117647171 117647967 117648092 117648336 117649402 117649484 117651666 117651711 117652804 117652821

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_39705

DMK:

116918361

DPZ:

124343264

PVM:	113826054 113826388

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:	111697035 111699764

LSM:

121129895

TCF:

131889794

PPOI:

119098374 119099252 119111651

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

CVS:	136982816(Skp2)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_F48E8.7(skpt-1)

CBR:	CBG_05188(Cbr-skpt-1)

CRQ:	GCK72_010539

LGI:	LOTGIDRAFT_162707

PVUL:

126818618

PCAN:

112574309

BGT:

106052054

GAE:	121368446 121374647

HRF:

HRJ:

CRG:

CANU:

CVN:	111120632 111121135

OED:

MYI:

PMAX:

MMER:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130629503 130629520 130629544

ATH:	AT1G21410(SKP2A) AT1G77000(SKP2B)

ALY:	9323729 9326504

CRB:	17896544 17900565

CSAT:

104702471 104715865 104743434 104751597 104756500 104776263

EUS:	EUTSA_v10008012mg EUTSA_v10018746mg

BRP:	103830576 103832158 103835748

BNA:	106354633 106376596 106377228 106390223 106425880 106440720 125574872

BOE:	106296844 106296874 106320805

RSZ:	108817317 108817460 108821994 108821995

THJ:	104804863 104810056 104812061

CPAP:

110818172

CIT:

102610462

CIC:	CICLE_v10001527mg

PVY:

116117187

MINC:

123203241 123229533

TCC:

18592471

GRA:	105769990 105774578 105783905 105797108 105799059

GHI:	107910407 107914131 107949523 107951467 107951990 107957709

GAB:	108464200 108476028 108480402

HSYR:

120155809 120206175 120218555

DZI:	111298713 111312230 111314993

EGR:

104449651

GMX:	100788845 100793275 100797840 100818928 121173056

GSJ:	114382553 114385121 114410360 114415475

PVU:	PHAVU_001G065400g PHAVU_009G133200g

VRA:	106763012 106778853

VAR:	108331909 108338715

VUN:	114163764 114193161

VUM:	124829513 124836521

CCAJ:

109789854 109815750

APRC:

113846879 113847982

MTR:	25482432 25489745

TPRA:

123896793

CAM:	101495232 101512090

PSAT:

127082717 127091052 127095036

VVO:

LJA:

ADU:

AIP:

AHF:	112706000 112765536

LANG:

109327037 109328396 109344329

PCIN:

129294109 129298080

QSA:	O6P43_015091 O6P43_019830

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103436619 103444539

MSYL:

126586261 126623197

PXB:	103934815 103951113 103957904

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:	110634552 110645417

MESC:

110606678 110609224

POP:	7466433 7469194

PEU:	105107575 105127719

PALZ:

118027496 118029200

JRE:	108981368 109013670

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107775581 107783609

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111372283 111373167 111408723

EGT:

105963399

SSPL:

121756154 121756437 121774510 121779701 121780139 121781084

SMIL:

130992896 131003382 131011782

SHIS:

125207486 125218949 125222183

APAN:

127246913

HAN:	110873514 110878514 110886203 110934745 110936667 110936668 110936669 110942172

ECAD:

122579939 122590293

LSV:	111901930 111904151

CCAV:

112502665

DCR:	108204796 108210979

CSIN:

114282551 114285553

RVL:

131306583

AEW:	130757908 130786923 130787504

BVG:

104905903

SOE:

110782035

CQI:	110685901 110725768

ATRI:

130810351

MOF:

131161744

NNU:	104599558 104606717

MING:

122072968 122090525 122093994

TSS:	122639661 122667781

PSOM:

113346432 113356462

OSA:	4324993 4338850

OBR:	102711806 102720653

OGL:	127774605 127782077

BDI:	100821602 100822312

ATS:	109741353 109743063

TDC:	119269956 119277966 119280222 119344814

TAES:

123056689 123062952 123071814 123080143 123133972 123182089

TUA:	125519001 125545595 125545597

LPER:

127313014 127345187

LRD:	124665579 124666461 124706470 124707878

SBI:	8058475 8063136

ZMA:	100274332 100274363

MFLO:

136450893 136459572 136497013 136512984 136513013 136516927

SITA:

101752546 101754500

SVS:	117849798 117858997

PVIR:

120665415 120673433 120698633 120708879

PHAI:

112884864 112895936

PDA:	103718718 103722202 120113029

EGU:	105037566 105045214

MUS:	103974333 103988146 104000225

ZOF:	121967256 121970132 121975224 122001399 122005719 122025690

DCT:

110116103

PEQ:

110024639

AOF:	109825128 109838057

MSIN:

131242631

NCOL:

116253264 116267102

ATR:

18436941

SMO:	SELMODRAFT_133097 SELMODRAFT_133180

PPP:	112279181 112288528 112289862

CSL:	COCSUDRAFT_55654

MBR:	MONBRDRAFT_34230

» show all

Reference

PMID:17962192

Authors

Nie L, Wu H, Sun XH

Title

Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP.

Journal

J Biol Chem 283:684-92 (2008)
DOI:10.1074/jbc.M704981200

Sequence

[hsa:6502]

Reference

PMID:16262255

Authors

Wang W, Nacusi L, Sheaff RJ, Liu X

Title

Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

Journal

Biochemistry 44:14553-64 (2005)
DOI:10.1021/bi051071j

Sequence

[hsa:6502]

Reference

PMID:12840033

Authors

Li X, Zhao Q, Liao R, Sun P, Wu X

Title

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation.

Journal

J Biol Chem 278:30854-8 (2003)
DOI:10.1074/jbc.C300251200

Sequence

[hsa:6502]

Reference

PMID:7553852

Authors

Zhang H, Kobayashi R, Galaktionov K, Beach D

Title

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.

Journal

Cell 82:915-25 (1995)
DOI:10.1016/0092-8674(95)90271-6

Sequence

[hsa:6502]

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Gene (2357)   
   KEGG GENES (1016)   
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