KEGG   ORTHOLOGY: K03910
Entry
K03910                      KO                                     

Symbol
A2M
Name
alpha-2-macroglobulin
Pathway
map04610  Complement and coagulation cascades
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03910  A2M; alpha-2-macroglobulin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03910  A2M; alpha-2-macroglobulin
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03910  A2M; alpha-2-macroglobulin
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03910  A2M; alpha-2-macroglobulin
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   K03910  A2M; alpha-2-macroglobulin
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    K03910  A2M; alpha-2-macroglobulin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K03910  A2M; alpha-2-macroglobulin
Other DBs
GO: 0004867
Genes
HSA: 2(A2M)
PTR: 465372(A2M)
PPS: 100979269
GGO: 101140582(A2M)
PON: 100173946(A2M)
NLE: 100595735
MCC: 716834
MCF: 102130734(A2M)
CSAB: 103218542
CATY: 105587966
RRO: 104672837(A2M)
RBB: 108543670(A2M)
TFN: 117090784
PTEH: 111526637
CJC: 100390764(A2M)
SBQ: 101030613(A2M)
MMU: 232345(A2m)
MPAH: 110316081(A2m)
RNO: 24153(A2m)
MCOC: 116099533(A2m)
MUN: 110546072(A2m)
CGE: 100755770
PLEU: 114700719
NGI: 103745223
HGL: 101704340(A2m)
CPOC: 100192394
CCAN: 109693593
OCU: 100349077
OPI: 101517212
TUP: 102474221(A2M)
CFA: 477699
VVP: 112917296
VLG: 121480031(A2M)
AML: 100469973
UMR: 103669158
UAH: 113257917
ORO: 101372899
ELK: 111142180
EJU: 114221675
MLX: 118025690
FCA: 101080460(A2M)
PYU: 121022091
PBG: 122473859(A2M)
PTG: 102958877(A2M)
PPAD: 109276052
AJU: 106965317(A2M)
HHV: 120226226
BTA: 513856(A2M)
BOM: 102268348(A2M)
BIU: 109559691
BBUB: 102402539
CHX: 102175560(A2M)
OAS: 101122940
ODA: 120858797
CCAD: 122423438
SSC: 403166(A2M)
CFR: 102516499
CBAI: 105062185
CDK: 105098164
BACU: 103017080
LVE: 103077690
OOR: 101271303
DLE: 111176737
PSIU: 116761004
ECB: 100061692
EPZ: 103561496
EAI: 106837424
MMYO: 118650732
MNA: 107544093
PKL: 118729850
HAI: 109372738(A2M)
DRO: 112321860
SHON: 119002132
AJM: 119065752
PDIC: 114513021
MMF: 118624307
RFQ: 117028331
PALE: 102895501(A2M)
PGIG: 120611701
RAY: 107501662
TOD: 119247730
LAV: 100657246(A2M)
TMU: 101349238
MDO: 100619502(A2M)
GAS: 123250456
SHR: 100930197(A2M)
PCW: 110213784(A2M)
OAA: 100090391
GGA: 100857394(A2ML3) 418251(A2M)
MGP: 100543551(A2M)
CJO: 107318451(A2M)
APLA: 101794357(A2M) 101801552
ACYG: 106048077
TGU: 100230740(A2M)
LSR: 110472323(A2M)
SCAN: 103812491 103812492(A2M)
PMOA: 120497756(A2M) 120498418
GFR: 102034966(A2M) 102035141
FAB: 101816338(A2M)
PHI: 102100027 102111407(A2M)
PMAJ: 107200672(A2M)
CCAE: 111925744(A2M) 111925769
CCW: 104690275 104690337(A2M)
FCH: 102048277
CLV: 102087055(A2M)
EGZ: 104122787(A2M)
ACUN: 113491062
PADL: 103922187(A2M) 103922191
AAM: 106495709
NPD: 112952031(A2M)
DNE: 112993889 112994445(A2M)
ASN: 102375395
AMJ: 106737178
CMY: 102941695
CPIC: 101948139
ACS: 100564843
PVT: 110090846
PBI: 103049361
PMUR: 107289646
TSR: 106556477
VKO: 123023286
GJA: 107109302
XLA: 100158443(a2m.S) 108696033
XTR: 100489060 619586(a2m)
NPR: 108799452
ALIM: 106536201
PSPA: 121309395
LCM: 102351715(A2M)
RTP: 109922073
BFO: 118410535
 » show all
Reference
  Authors
Anderson RB, Cianciolo GJ, Kennedy MN, Pizzo SV
  Title
Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism.
  Journal
J Leukoc Biol 83:381-92 (2008)
DOI:10.1189/jlb.0407236
  Sequence
[hsa:2]

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