KEGG   ORTHOLOGY: K03986
Entry
K03986                      KO                                     

Name
C1QA
Definition
complement C1q subcomponent subunit A
Pathway
ko04610  Complement and coagulation cascades
ko05020  Prion disease
ko05133  Pertussis
ko05142  Chagas disease
ko05150  Staphylococcus aureus infection
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H01357  Allergic contact dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03986  C1QA; complement C1q subcomponent subunit A
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03986  C1QA; complement C1q subcomponent subunit A
  09164 Neurodegenerative disease
   05020 Prion disease
    K03986  C1QA; complement C1q subcomponent subunit A
  09171 Infectious disease: bacterial
   05133 Pertussis
    K03986  C1QA; complement C1q subcomponent subunit A
   05150 Staphylococcus aureus infection
    K03986  C1QA; complement C1q subcomponent subunit A
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K03986  C1QA; complement C1q subcomponent subunit A
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03986  C1QA; complement C1q subcomponent subunit A
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03986  C1QA; complement C1q subcomponent subunit A
Other DBs
GO: 0005602
Genes
HSA: 712(C1QA)
PTR: 749231(C1QA)
PPS: 100993798(C1QC)
PON: 100433850(C1QA)
NLE: 100606692(C1QA)
MCC: 708477(C1QA)
MCF: 107126479(C1QA)
CSAB: 103225410(C1QA)
RRO: 104663224(C1QA)
RBB: 108538441(C1QA)
CJC: 100388215(C1QA)
SBQ: 101048882(C1QA)
MMU: 12259(C1qa)
MCAL: 110293043(C1qa)
MPAH: 110323698(C1qa)
RNO: 298566(C1qa)
MUN: 110545386(C1qa)
CGE: 100766409(C1qa)
NGI: 103746398(C1qa)
HGL: 101703487(C1qa)
TUP: 102485542(C1QA)
CFA: 478194(C1QA)
VVP: 112930176(C1QA)
AML: 100465747(C1QA)
UMR: 103666574(C1QA) 103666575
UAH: 113268538(C1QA)
ORO: 101373207(C1QA)
FCA: 101096082(C1QA)
PTG: 102971698(C1QA)
PPAD: 109274281(C1QA)
BTA: 534961(C1QA)
BOM: 102265266(C1QA)
BIU: 109574058(C1QA)
BBUB: 102404539(C1QA)
CHX: 102187545(C1QA)
OAS: 101102126(C1QA)
SSC: 445461(C1QA)
CDK: 105088872(C1QA)
BACU: 103010752(C1QA)
LVE: 103086829(C1QA)
OOR: 101272352(C1QA)
DLE: 111163328(C1QA)
PCAD: 102973376(C1QA)
ECB: 100058097(C1QA)
EPZ: 103541873(C1QA)
EAI: 106839999(C1QA)
MYB: 102256044(C1QA)
MYD: 102757592(C1QA)
MNA: 107538383(C1QA)
HAI: 109396736(C1QA)
DRO: 112299476(C1QA)
PALE: 102888216(C1QA)
RAY: 107513061(C1QA)
MJV: 108407306(C1QA)
LAV: 100664959(C1QA)
TMU: 101349199
MDO: 100025524(C1QA)
PCW: 110206037(C1QA)
GGA: 419504(C1QA)
MGP: 100546926(C1QA)
CJO: 107323570(C1QA)
NMEL: 110408714(C1QA)
APLA: 101803758(C1QA)
TGU: 101233409
LSR: 110472263(C1QA)
GFR: 102035884(C1QA)
FAB: 101806915(C1QA)
PHI: 102105876(C1QA)
PMAJ: 107213706(C1QA)
CCAE: 111938565(C1QA)
ETL: 114070038(C1QA)
FPG: 101914525(C1QA)
FCH: 102055875(C1QA)
CLV: 102098735(C1QA)
EGZ: 104131865(C1QA)
NNI: 104011202(C1QA)
ACUN: 113487921(C1QA)
PADL: 103925401(C1QA)
AAM: 106496018(C1QA)
ASN: 102386091(C1QA)
PSS: 102457446
CPIC: 101942058(C1QA)
ACS: 100556677
PVT: 110089367(C1QA)
PBI: 103066936(C1QA)
PMUR: 107284661(C1QA)
GJA: 107125363(C1QA)
XLA: 108705065(c1qa.L)
NPR: 108803991(C1QA)
DRE: 553548(c1qa)
CCAR: 109069311
IPU: 108279317
PHYP: 113541366
AMEX: 103023699
EEE: 113575069
OLA: 101157838
KMR: 108249495
ALIM: 106529100
BPEC: 110173580
ELS: 105005628
LCM: 102356609
CMK: 103187678
 » show all
Reference
  Authors
Georgakopoulos T, Tatford OC, Gurevich V, Bertolini J
  Title
C1q aggregate binding for the determination of anti-complementary activity of immunoglobulin products.
  Journal
Biologicals 39:38-42 (2011)
DOI:10.1016/j.biologicals.2010.11.002
  Sequence
[hsa:712]
Reference
PMID:1940381
  Authors
Petry F, Reid KB, Loos M
  Title
Gene expression of the A- and B-chain of mouse C1q in different tissues and the characterization of the recombinant A-chain.
  Journal
J Immunol 147:3988-93 (1991)
  Sequence
[mmu:12259]

KEGG   ORTHOLOGY: K03987
Entry
K03987                      KO                                     

Name
C1QB
Definition
complement C1q subcomponent subunit B
Pathway
ko04610  Complement and coagulation cascades
ko05020  Prion disease
ko05133  Pertussis
ko05142  Chagas disease
ko05150  Staphylococcus aureus infection
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03987  C1QB; complement C1q subcomponent subunit B
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03987  C1QB; complement C1q subcomponent subunit B
  09164 Neurodegenerative disease
   05020 Prion disease
    K03987  C1QB; complement C1q subcomponent subunit B
  09171 Infectious disease: bacterial
   05133 Pertussis
    K03987  C1QB; complement C1q subcomponent subunit B
   05150 Staphylococcus aureus infection
    K03987  C1QB; complement C1q subcomponent subunit B
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K03987  C1QB; complement C1q subcomponent subunit B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03987  C1QB; complement C1q subcomponent subunit B
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03987  C1QB; complement C1q subcomponent subunit B
Other DBs
GO: 0005602
Genes
HSA: 713(C1QB)
PTR: 469214(C1QB)
PPS: 100994127(C1QB)
GGO: 101124764(C1QB)
PON: 100435212(C1QB)
NLE: 100607840(C1QB)
MCC: 718307(C1QB)
MCF: 102139434(C1QB)
CSAB: 103225408(C1QB)
RRO: 104663227(C1QB)
RBB: 108538439(C1QB)
CJC: 100405501(C1QB)
SBQ: 101049399(C1QB)
MMU: 12260(C1qb)
MCAL: 110292976(C1qb)
MPAH: 110323604(C1qb)
RNO: 29687(C1qb)
MUN: 110545384(C1qb)
CGE: 100766700(C1qb)
NGI: 103746400(C1qb)
HGL: 101704691(C1qb)
TUP: 102492509(C1QB)
CFA: 487381(C1QB)
VVP: 112930158(C1QB)
AML: 100466574(C1QB)
UMR: 103666571(C1QB)
UAH: 113268536(C1QB)
ORO: 101372635(C1QB)
FCA: 101096331(C1QB)
PTG: 102972468(C1QB)
PPAD: 109274283(C1QB)
BTA: 617435(C1QB)
BOM: 102264986(C1QB)
BIU: 109574037(C1QB)
BBUB: 102405769(C1QB)
CHX: 102186813(C1QB)
SSC: 100518846(C1QB)
CFR: 116668289(C1QB)
CDK: 105088875(C1QB)
BACU: 103011614(C1QB)
LVE: 103086274(C1QB)
OOR: 101273379(C1QB)
DLE: 111163327(C1QB)
PCAD: 102978873(C1QB)
ECB: 100071667(C1QB)
EPZ: 103541871(C1QB)
EAI: 106839997(C1QB)
MYB: 102255230(C1QB)
MYD: 102756834(C1QB)
MNA: 107538377(C1QB)
HAI: 109396733(C1QB)
DRO: 112299478(C1QB)
PALE: 102887385(C1QB)
RAY: 107513063(C1QB)
MJV: 108407308(C1QB)
LAV: 100663347(C1QB)
TMU: 101348685
MDO: 100029312(C1QB)
PCW: 110206039(C1QB)
OAA: 114812254(C1QB)
GGA: 428197(C1QB)
MGP: 100546619(C1QB)
CJO: 107323571(C1QB)
NMEL: 110408713(C1QB)
APLA: 101803105(C1QB)
ACYG: 106040156
TGU: 100223187(C1QB)
LSR: 110472265(C1QB)
SCAN: 103824164(C1QB)
GFR: 102035536(C1QB)
FAB: 101807280(C1QB)
PHI: 102105506(C1QB)
PMAJ: 107213705(C1QB)
CCAE: 111938538(C1QB)
CCW: 104697576(C1QB)
ETL: 114070039(C1QB)
FPG: 101922426(C1QB)
FCH: 102049289(C1QB)
CLV: 106145645(C1QB)
EGZ: 104131867(C1QB)
NNI: 104011205(C1QB)
ACUN: 113487920(C1QB)
PADL: 103925403(C1QB)
AAM: 106496016(C1QB)
ASN: 102376788(C1QB)
PSS: 102446475
CMY: 102940493
CPIC: 101942579(C1QB)
PVT: 110089371(C1QB)
PBI: 103067397(C1QB)
PMUR: 107284659(C1QB)
TSR: 106540987
PMUA: 114602587(C1QB)
XLA: 444263(c1qb.L)
XTR: 116408190
NPR: 108804086(C1QB)
SRX: 107719010
SANH: 107703483
SGH: 107551611
AMEX: 103024341
TRU: 101062052
NCC: 104944663
MZE: 101477831
ONL: 100693084
OLA: 101168703
XMA: 102220190
XCO: 114135610
PRET: 103464343
ALIM: 106529098
POV: 109635432
SDU: 111219398
SLAL: 111657333
MALB: 109966384
SASA: 100380615(c1qb)
OTW: 112246338
SFM: 108924692
PKI: 111838022
LCM: 106705089(C1QB)
RTP: 109918419
APLC: 110990329
 » show all
Reference
  Authors
Tissot B, Gonnet F, Iborra A, Berthou C, Thielens N, Arlaud GJ, Daniel R
  Title
Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan.
  Journal
Biochemistry 44:2602-9 (2005)
DOI:10.1021/bi047802h
  Sequence
[hsa:713]
Reference
PMID:3000358
  Authors
Reid KB
  Title
Molecular cloning and characterization of the complementary DNA and gene coding for the B-chain of subcomponent C1q of the human complement system.
  Journal
Biochem J 231:729-35 (1985)
DOI:10.1042/bj2310729
  Sequence
[hsa:713]

KEGG   ORTHOLOGY: K03988
Entry
K03988                      KO                                     

Name
C1QG
Definition
complement C1q subcomponent subunit C
Pathway
ko04610  Complement and coagulation cascades
ko05020  Prion disease
ko05133  Pertussis
ko05142  Chagas disease
ko05150  Staphylococcus aureus infection
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03988  C1QG; complement C1q subcomponent subunit C
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03988  C1QG; complement C1q subcomponent subunit C
  09164 Neurodegenerative disease
   05020 Prion disease
    K03988  C1QG; complement C1q subcomponent subunit C
  09171 Infectious disease: bacterial
   05133 Pertussis
    K03988  C1QG; complement C1q subcomponent subunit C
   05150 Staphylococcus aureus infection
    K03988  C1QG; complement C1q subcomponent subunit C
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K03988  C1QG; complement C1q subcomponent subunit C
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03988  C1QG; complement C1q subcomponent subunit C
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03988  C1QG; complement C1q subcomponent subunit C
Genes
HSA: 714(C1QC)
GGO: 101141927(C1QC)
PON: 100432946(C1QC)
NLE: 100607041(C1QC)
MCC: 708589(C1QC)
MCF: 102130549(C1QC)
CSAB: 103225409(C1QC)
RRO: 104663226(C1QC)
RBB: 108538440(C1QC)
CJC: 100894768(C1QC)
SBQ: 101048354(C1QC)
MMU: 12262(C1qc)
MCAL: 110293122(C1qc)
MPAH: 110323611(C1qc)
RNO: 362634(C1qc)
MUN: 110545387(C1qc)
CGE: 100769576(C1qc)
NGI: 103746399(C1qc)
HGL: 101704347(C1qc)
TUP: 102485114(C1QC)
CFA: 487382(C1QC)
VVP: 112930142(C1QC)
AML: 100466162(C1QC)
UMR: 103666572(C1QC)
UAH: 113268537(C1QC)
ORO: 101372926(C1QC)
FCA: 101094773(C1QC)
PTG: 102972183(C1QC)
PPAD: 109274282(C1QC)
BTA: 509968(C1QC)
BOM: 102265742(C1QC)
BIU: 109574050(C1QC)
BBUB: 102404864(C1QC)
CHX: 102187279(C1QC)
SSC: 445460(C1QC)
CFR: 116668288(C1QC)
CDK: 105088874(C1QC)
BACU: 103011042(C1QC)
LVE: 103086559(C1QC)
OOR: 101271771(C1QC)
DLE: 111163329(C1QC)
PCAD: 102973652(C1QC)
ECB: 100058056(C1QC)
EPZ: 103541872(C1QC)
EAI: 106839998(C1QC)
MYB: 102255536(C1QC)
MYD: 102757117(C1QC)
MNA: 107538381(C1QC)
HAI: 109396734(C1QC)
DRO: 112299477(C1QC)
PALE: 102887798(C1QC)
RAY: 107513062(C1QC)
LAV: 100663063(C1QC)
TMU: 101348943
MDO: 100025508(C1QC)
SHR: 100918112
PCW: 110206038(C1QC)
OAA: 100080523(C1QC) 100089335(C1QA)
GGA: 419503(C1QC)
MGP: 100546774(C1QC)
CJO: 107323573
NMEL: 110408716(C1QC)
APLA: 101803553(C1QC)
ACYG: 106040121
TGU: 100220290(C1QC)
LSR: 110472264(C1QC)
SCAN: 103824163
GFR: 102035709(C1QC)
FAB: 101807106(C1QC)
PHI: 102105689(C1QC)
PMAJ: 107213704
CCAE: 111938564
CCW: 104697545
ETL: 114070037(C1QC)
FPG: 101914345(C1QC)
FCH: 102056038(C1QC)
CLV: 102084244
EGZ: 104131866(C1QC)
NNI: 104011204(C1QC)
ACUN: 113487922(C1QC)
PADL: 103925402(C1QC)
AAM: 106496017(C1QC)
ASN: 102386342(C1QC)
CMY: 102934891(C1QC)
CPIC: 101942313(C1QC)
PVT: 110089370(C1QC)
PBI: 112541306(C1QC)
PMUR: 107284660(C1QC)
TSR: 106540986
PMUA: 114602965
GJA: 107116694(C1QC)
XLA: 443602(c1qc.L)
XTR: 116408192(c1qc)
NPR: 108803990
DRE: 449803(c1qc)
SRX: 107719009
SANH: 107703482
SGH: 107551612
CCAR: 109069312
IPU: 108278434 108278436(C1qb)
AMEX: 103024031
EEE: 113574249
OLA: 101161146
KMR: 108249501
ALIM: 106529075
POV: 109635433
BPEC: 110173579
SASA: 106591842(C1QC)
OTW: 112246341
SALP: 112072903
ELS: 105005629
SFM: 108924765
LCM: 106705088
CMK: 103187652(c1qb)
RTP: 109918420
APLC: 110973230
 » show all
Reference
  Authors
Hosszu KK, Santiago-Schwarz F, Peerschke EI, Ghebrehiwet B
  Title
Evidence that a C1q/C1qR system regulates monocyte-derived dendritic cell differentiation at the interface of innate and acquired immunity.
  Journal
Innate Immun 16:115-27 (2010)
DOI:10.1177/1753425909339815
  Sequence
[hsa:714]
Reference
PMID:1396691
  Authors
Petry F, Reid KB, Loos M
  Title
Isolation, sequence analysis and characterization of cDNA clones coding for the C chain of mouse C1q. Sequence similarity of complement subcomponent C1q, collagen  type VIII and type X and precerebellin.
  Journal
Eur J Biochem 209:129-34 (1992)
DOI:10.1111/j.1432-1033.1992.tb17269.x
  Sequence
[mmu:12262]

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