KEGG   ORTHOLOGY: K03990
Entry
K03990                      KO                                     

Name
C3
Definition
complement component 3
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04145  Phagosome
ko04610  Complement and coagulation cascades
ko05131  Shigellosis
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05203  Viral carcinogenesis
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H00821  Age-related macular degeneration
H01434  Atypical hemolytic uremic syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03990  C3; complement component 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K03990  C3; complement component 3
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03990  C3; complement component 3
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K03990  C3; complement component 3
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03990  C3; complement component 3
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03990  C3; complement component 3
   05133 Pertussis
    K03990  C3; complement component 3
   05134 Legionellosis
    K03990  C3; complement component 3
   05150 Staphylococcus aureus infection
    K03990  C3; complement component 3
   05152 Tuberculosis
    K03990  C3; complement component 3
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K03990  C3; complement component 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K03990  C3; complement component 3
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K03990  C3; complement component 3
   05142 Chagas disease
    K03990  C3; complement component 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03990  C3; complement component 3
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03990  C3; complement component 3
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03990  C3; complement component 3
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   K03990  C3; complement component 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03990  C3; complement component 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   K03990  C3; complement component 3
Genes
HSA: 718(C3)
PTR: 455644(C3)
PPS: 100982432(C3)
GGO: 101139062(C3)
PON: 100446798(C3)
NLE: 100598784(C3)
MCC: 703613(C3)
MCF: 102131458(C3)
CSAB: 103234342(C3)
RRO: 104665361(C3)
RBB: 108534593(C3)
CJC: 100400501(C3)
SBQ: 101044671(C3)
MMU: 12266(C3)
MCAL: 110312494(C3)
MPAH: 110335652(C3)
RNO: 24232(C3)
MUN: 110545607(C3)
CGE: 100763958(C3)
NGI: 103737182(C3)
HGL: 101726247(C3)
CCAN: 109694300(C3) 109698715
TUP: 102487294(C3)
CFA: 476728(C3)
VVP: 112911820(C3)
AML: 100472549(C3)
UMR: 103681871(C3)
UAH: 113242886(C3)
ORO: 101385252(C3)
ELK: 111161841
FCA: 101088468
PPAD: 109261021(C3) 109261022
BTA: 280677(C3)
BOM: 102270836(C3)
BIU: 109561686(C3)
BBUB: 102407588(C3)
CHX: 100860826(C3)
OAS: 101108131
SSC: 397072(C3)
CFR: 102512172(C3)
CDK: 105104550(C3)
BACU: 103011779(C3)
LVE: 103083690(C3)
OOR: 101281425(C3)
DLE: 111166019(C3)
PCAD: 102979432(C3)
EPZ: 103540378(C3)
EAI: 106832730(C3)
MYD: 102754026
MNA: 107525753(C3)
DRO: 112312430(C3)
PALE: 102882350(C3)
RAY: 107511212(C3)
MJV: 108401780(C3)
LAV: 100657489(C3)
TMU: 101350977
MDO: 100020034(C3)
SHR: 100934148(C3)
PCW: 110197414(C3)
GGA: 396370(C3)
MGP: 100551026(C3)
NMEL: 110391242(C3)
ACYG: 106049436(C3)
TGU: 100222821(C3)
GFR: 102043273
FAB: 101805832
PHI: 102102912(C3)
FPG: 101923177(C3)
FCH: 102047045(C3)
CLV: 102087426(C3)
EGZ: 104129973(C3)
NNI: 104014965(C3)
ACUN: 113490564(C3)
PADL: 103916897(C3)
PSS: 102452901(C3)
CMY: 102933485
ACS: 100555124(c3)
PVT: 110090193
PBI: 103048059(C3)
PMUR: 107287994
PMUA: 114587731
GJA: 107125723
NPR: 108794623(C3)
DRE: 30491(c3a.2) 321046(c3a.1) 494039(c3a.6) 565074(c3a.3)
CCAR: 109074247
PHYP: 113537390
AMEX: 103045627
EEE: 113591926
TRU: 101066599(c3)
LCO: 104939795
OLA: 100125801(c3-1)
XMA: 102235663
XCO: 114144597
PRET: 103475608(c3)
CVG: 107082431
NFU: 107391903(c3)
KMR: 108241457
ALIM: 106528528(c3)
AOCE: 111584065(c3)
CSEM: 103383921
POV: 109627599
LCF: 108885437
SDU: 111229209
SLAL: 111665554(c3)
HCQ: 109527282(c3)
BPEC: 110166125
MALB: 109952399(c3)
SFM: 108919697
PKI: 111841378(c3)
LCM: 102353531(C3)
CMK: 103191243(c3)
RTP: 109916785
CIN: 445694(c3-1)
SPU: 373284(c3)
 » show all
Reference
PMID:2579379
  Authors
de Bruijn MH, Fey GH
  Title
Human complement component C3: cDNA coding sequence and derived primary structure.
  Journal
Proc Natl Acad Sci U S A 82:708-12 (1985)
DOI:10.1073/pnas.82.3.708
  Sequence
[hsa:718]
Reference
  Authors
Murray I, Kohl J, Cianflone K
  Title
Acylation-stimulating protein (ASP): structure-function determinants of cell surface binding and triacylglycerol synthetic activity.
  Journal
Biochem J 342 ( Pt 1):41-8 (1999)
DOI:10.1042/bj3420041
  Sequence
[hsa:718]

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