KEGG ORTHOLOGY: K04011

ORTHOLOGY: K04011

Entry

K04011                      KO

Symbol

CR1, CD35

Name

complement component (3b/4b) receptor 1

Pathway

map04610

Complement and coagulation cascades

map04613

Neutrophil extracellular trap formation

map04640

Hematopoietic cell lineage

map05134

Legionellosis

map05140

Leishmaniasis

map05144

Malaria

map05152

Tuberculosis

Disease

H00361

Malaria

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   04610 Complement and coagulation cascades
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   04613 Neutrophil extracellular trap formation
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   05152 Tuberculosis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
  09174 Infectious disease: parasitic
   05144 Malaria
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   05140 Leishmaniasis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
CD molecules [BR:ko04090]
Proteins
  K04011  CD35, CR1; complement component (3b/4b) receptor 1

Other DBs

GO:	0004877 0001861

Genes

HSA:	1378(CR1) 1379(CR1L)

PTR:	449643(CR1)

PPS:	100982795(CR1)

GGO:	101139740(CR1)

PON:	100443325(CR1)

PPYG:

129035459(CR1)

NLE:	100587880(CR1)

SSYN:

129458600(CR1)

MCC:	718120(CR1)

MCF:	102116805(CR1L) 102117401(CR1)

MTHB:

126949087

MNI:	105484964(CR1)

CSAB:

103230172(CR1L) 103231020(CR1)

CATY:

105577086(CR1) 105577089(CR1L)

PANU:

101016492

TGE:	112631312(CR1)

MLEU:

105536432(CR1)

RRO:	104664179 104664181(CR1L)

RBB:	108530296 108539534(CR1) 108539535

TFN:	117075393 117075394

PTEH:

111531168(CR1)

CANG:

105508881(CR1)

CJC:	100396861 103790668

SBQ:	101048758(CR1) 104651759(CR1L)

CIMI:

108302105(CR1)

ANAN:

105721912 135268209

MMUR:

105868175 109730106

LCAT:

123626890(CR1)

PCOQ:

105805845(CR1)

OGA:	100947887(CR1)

MMU:	12946(Cr1l)

MCAL:

110289966(Cr1l)

MPAH:

110321621(Cr1l)

RNO:	54243(Cr1l)

CGE:	100772783(Cr1l)

PROB:

127223973(Cr1l)

PLEU:

114687532 114687533(Cr1l)

NGI:	103727019(Cr1l)

HGL:

CCAN:

DSP:

NCAR:

MMMA:

OCU:

OPI:

TUP:	102486522(CR1) 106736063

GVR:

103596051

VVP:	112910984 112910991

VLG:

121492857

AML:

100480199

UMR:

103672539

UAR:	123785798(CR1)

ELK:	111150949 111162350

LLV:

125086031

MPUF:

101670537(CR1L)

MLK:	131814397(CR1)

ORO:	101384034(CR1L)

ZCA:	113933203(CR1L)

MLX:	118014262(CR1L)

FCA:	102899461(CR1L)

PCOO:

112857686(CR1)

PBG:	122475746(CR1L)

PVIV:

125155671(CR1L)

LRUF:

124510073

PTG:	102963346(CR1)

PPAD:

109255305(CR1L)

PUC:

125925340

AJU:

106981814

HHV:	120230486 120230504

BTA:	100138386(CR1L)

CHX:

102187247

OAS:

105614152

MBEZ:

129551005(CR1L)

SSC:	100623585(CR1)

CFR:	102520980(CR1)

CBAI:

105075451(CR1)

CDK:	105100014(CR1) 116148703(CR1L)

VPC:	102528250(CR1)

BACU:

102998630(CR1)

BMUS:

118884475(CR1)

OOR:	101290167(CR1)

DLE:	111184732(CR1)

PSIU:

116760667

NASI:

112403443(CR1L) 112403485

ECB:	106783153(CR1L)

EPZ:	103541409 103556836(CR1) 103556844(CR1L)

MYB:	102258516(CR1)

MYD:

102768212

MMYO:

118673246(CR1)

MLF:	102418475(CR1) 111827234

MDT:	132221243(CR1)

PKL:	118721675(CR1)

EFUS:

103297471(CR1)

MNA:	107543130(CR1)

DRO:	112318208(CR1)

SHON:

118980775 118982574

AJM:	119056794(CR1L) 119058024(CR1)

PDIC:

114512109(CR1)

PHAS:

123826717(CR1)

PPAM:

129062463(CR1)

HAI:	109377857(CR1)

RFQ:	117015038(CR1)

PALE:

102890927

RAY:	107497854(CR1) 107506394

LAV:

TMU:

ETF:

DNM:

AFZ:

TVP:

OAA:	100078027(CD46)

GGA:	419853(CR1L)

MGP:	100548828 100548983 100549292

CJO:

107324773

NMEL:

110388368(CR1) 110388376

ACYG:

106041274(CR1)

TGU:

100232607

LSR:	110473053(CR1L)

SCAN:

103823334

PMOA:

120495860(CR1)

OTC:

121347945

PRUF:

121353306(CR1)

GFR:	102045325 102045428 102045490

FAB:	101813858(CR1)

OMA:

130263545

PHI:	102102097(CR1)

PMAJ:

107214784(CR2)

CCAE:

CCW:

CBRC:

ETL:

ZAB:	102075373(CR1)

ZLE:	135457959(CR1)

MMEA:

130584996 130585009

SATI:

136371456

FPG:	101918890(CR1)

FCH:	102052627(CR1L)

ACUN:

113488794(CR1)

TALA:

ACHC:

HALD:

HLE:

DPUB:

EGZ:

NNI:

PADL:

FGA:

GSTE:

CLV:	102085822(CR1)

MUI:

PGUU:

PLET:

EHS:

CMAC:

BREG:

ACAR:

CPEA:

CVF:

RTD:	128900460(CR1)

AAM:	106490971 106490974 106490975

DNE:	112990190(CR2)

ASN:	102376928(CR1) 102386950 102388420 112548818

AMJ:	102559090(CR1L) 102559514 102559728(CR1)

PSS:	102450308 102451319

CCAY:

125625224

DCC:	119846317 119846526

CPIC:

101935074 101940909 101943449 101943731 103306411

TST:	117875748 117876533 117876535

MRV:	120393911 120393913 120403910 120403911 120403915 120403916

ACS:	103279619 107983170

ASAO:

132773376 132773377 132773594(CR1)

PVT:	110086557 110086565(CR1)

SUND:

121928961(CR2)

PBI:	103054975 103059413(CR2)

PMUR:

PGUT:

APRI:

VKO:

PMUA:

PRAF:

128415132(CR1)

ZVI:	118088521(CR1)

HCG:	128323132(CR1)

STOW:

125432699 125432700

EMC:	129330399(CR1)

NPR:

GSH:

IPU:

TRU:

MZE:

CMK:

CIN:

CSCU:

CANU:

Reference

PMID:2972794

Authors

Klickstein LB, Bartow TJ, Miletic V, Rabson LD, Smith JA, Fearon DT

Title

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.

Journal

J Exp Med 168:1699-717 (1988)
DOI:10.1084/jem.168.5.1699

Sequence

[hsa:1378]

Reference

PMID:23416052

Authors

Ogembo JG, Kannan L, Ghiran I, Nicholson-Weller A, Finberg RW, Tsokos GC, Fingeroth JD

Title

Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.

Journal

Cell Rep 3:371-85 (2013)
DOI:10.1016/j.celrep.2013.01.023

Sequence

[hsa:1378]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (313)   
   KEGG GENES (252)   
   KEGG MGENES (2)   
   RefGene (45)   
   OC (14)   
Literature (2)   
   PubMed (2)   
All databases (335)   

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