KEGG   ORTHOLOGY: K04100Help
Entry
K04100                      KO                                     

Name
ligA
Definition
protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8]
Pathway
ko00362  Benzoate degradation
ko00624  Polycyclic aromatic hydrocarbon degradation
ko00627  Aminobenzoate degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K04100  ligA; protocatechuate 4,5-dioxygenase, alpha chain
   00627 Aminobenzoate degradation
    K04100  ligA; protocatechuate 4,5-dioxygenase, alpha chain
   00624 Polycyclic aromatic hydrocarbon degradation
    K04100  ligA; protocatechuate 4,5-dioxygenase, alpha chain
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.8  protocatechuate 4,5-dioxygenase
     K04100  ligA; protocatechuate 4,5-dioxygenase, alpha chain
BRITE hierarchy
Other DBs
RN: R01632 R03550 R04280 R09272 R09565
GO: 0018579
Genes
XCC: XCC0805(ligA)
XCB: XC_3426
XCA: xcc-b100_3546(ligA)
XCP: XCR_0985
XCV: XCV0914(ligA)
XAX: XACM_0860
XAC: XAC0879(ligA)
XCI: XCAW_03701(ligA)
XCT: J151_01006
XCJ: J158_01003
XOM: XOO3524(XOO3524)
XOR: XOC_0930
XPH: XppCFBP6546_07115(XppCFBP6546P_07115)
PPUT: L483_17500
PAT: Patl_3886
CSA: Csal_0325
RFO: REIFOR_00545(ligA)
BPH: Bphy_3205
BPX: BUPH_06639(ligA)
PPNO: DA70_15135
PPNM: LV28_15545
PSPU: NA29_05505
PAPI: SG18_10090
HYF: DTO96_100892(ligA_1)
AFQ: AFA_05520(ligA)
AAQU: D3M96_07060(ligA)
ACRA: BSY15_1237
VEI: Veis_1369
CTES: O987_16265
COF: FOZ74_08485(ligA)
RTA: Rta_24770
LIM: L103DPR2_01497(ligA_1) L103DPR2_01514(ligA_2)
LIH: L63ED372_01144(ligA_1)
HYR: BSY239_1243(ligA) BSY239_2223(ligA)
HYC: E5678_08760(ligA)
HPSE: HPF_08080(ligA1) HPF_08185(ligA2)
SNN: EWH46_19140(ligA)
DAR: Daro_3249
AZO: azo2523(ligA1) azo2538(ligA2)
TCL: Tchl_1061
BRA: BRADO2341(ligA) BRADO2379
BBT: BBta_2701(ligA) BBta_2733
BRO: BRAD285_4959(ligA) BRAD285_4996(ligA)
RPA: RPA1006 RPA4701(ligA)
RPD: RPD_0983
RPE: RPE_0750
MALG: MALG_02286
HBA: Hbal_2593
NOV: TQ38_025025(ligA) TQ38_028410(ligA)
SPHP: LH20_03910
SMAZ: LH19_17695
SPHI: TS85_18515
SSAN: NX02_17505
SPHC: CVN68_17245(ligA)
SPHR: BSY17_3447(ligA)
SHYD: CJD35_16820(ligA) CJD35_19575(ligA)
SYA: A6768_17480(ligA)
SFLA: SPHFLASMR4Y_02987(ligA)
SPHY: CHN51_00895(ligA)
BLAS: BSY18_3523(ligA)
RDI: CMV14_06885(ligA)
SPHS: ETR14_07930(ligA)
AAY: WYH_01046(ligA_2) WYH_01908(ligA_3) WYH_03215(ligA_4)
ADO: A6F68_01080(ligA_1)
POT: E2E27_18120(ligA)
MAG: amb0257
MAGX: XM1_1094
MAGN: WV31_13630
TMO: TMO_b0114
MAGQ: MGMAQ_2662(ligA) MGMAQ_2669(ligA)
NCB: C0V82_22495(ligA)
AMIN: AUMI_19390
AUW: AURUGA1_00419(ligA_1)
SRO: Sros_4716
BSD: BLASA_2598(ligA)
MMAR: MODMU_2844(ligA)
PDX: Psed_2465
PAUT: Pdca_48150
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2185230
  Authors
Noda Y, Nishikawa S, Shiozuka K, Kadokura H, Nakajima H, Yoda K, Katayama Y, Morohoshi N, Haraguchi T, Yamasaki M
  Title
Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis.
  Journal
J Bacteriol 172:2704-9 (1990)
DOI:10.1128/JB.172.5.2704-2709.1990

KEGG   ORTHOLOGY: K04101Help
Entry
K04101                      KO                                     

Name
ligB
Definition
protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
Pathway
ko00362  Benzoate degradation
ko00624  Polycyclic aromatic hydrocarbon degradation
ko00627  Aminobenzoate degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K04101  ligB; protocatechuate 4,5-dioxygenase, beta chain
   00627 Aminobenzoate degradation
    K04101  ligB; protocatechuate 4,5-dioxygenase, beta chain
   00624 Polycyclic aromatic hydrocarbon degradation
    K04101  ligB; protocatechuate 4,5-dioxygenase, beta chain
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.8  protocatechuate 4,5-dioxygenase
     K04101  ligB; protocatechuate 4,5-dioxygenase, beta chain
BRITE hierarchy
Other DBs
RN: R01632 R03550 R04280 R09272 R09565
GO: 0018579
Genes
XCC: XCC0804(pcaH)
XCB: XC_3427
XCA: xcc-b100_3547(ligB)
XCP: XCR_0984
XCV: XCV0913(ligB)
XAX: XACM_0859(ligB)
XAC: XAC0878(pcaH)
XCI: XCAW_03702(pcaH)
XCT: J151_01005
XCJ: J158_01002
XOO: XOO3734(pcaH)
XOM: XOO3525(XOO3525)
XOP: PXO_04631
XOR: XOC_0929
XPH: XppCFBP6546_07120(XppCFBP6546P_07120)
PAT: Patl_3885
CSA: Csal_0324
RFO: REIFOR_00546(ligB)
KKI: KKKWG1_0313(ligB)
BPH: Bphy_3204
PPNO: DA70_15140
PPNM: LV28_15540
PSPU: NA29_05500
PAPI: SG18_10085
HYF: DTO96_100893(ligB)
AFQ: AFA_05515
ACRA: BSY15_1238
CTES: O987_16260
RTA: Rta_24760
LIM: L103DPR2_01498(ligB_1) L103DPR2_01515(ligB_2)
LIH: L63ED372_01145(ligB)
HPSE: HPF_08085(ligB1) HPF_08190(ligB2)
DAR: Daro_3248
AZO: azo2522(ligB1) azo2537(ligB2)
TCL: Tchl_1062
BRA: BRADO2342(ligB) BRADO2380(mhpB)
BBT: BBta_2702(ligB) BBta_2734(mhpB)
BRO: BRAD285_4958(ligB) BRAD285_4995(ligB)
RPA: RPA1007(mhpB) RPA4702(ligB)
RPD: RPD_0982
RPE: RPE_0751
MMED: Mame_04593(ligB)
MALG: MALG_02287
HBA: Hbal_2592
SMAZ: LH19_17690
SPHI: TS85_18520
SSAN: NX02_17500
SPHB: EP837_03494(ligB)
SPHR: BSY17_3446(ligB)
SFLA: SPHFLASMR4Y_02988(ligB)
BLAS: BSY18_3524(ligB)
AAY: WYH_01045(ligB_1) WYH_01909(ligB_2) WYH_03214(ligB_3)
ADO: A6F68_01079(ligB)
MAG: amb0258
MAGX: XM1_1091 XM1_1095(ligB)
ABS: AZOBR_p310188(mhpB)
TMO: TMO_b0115(mhpB)
MAGQ: MGMAQ_2661(ligB) MGMAQ_2670(ligB)
AMIN: AUMI_19380
AUW: AURUGA1_00420(ligB)
SRO: Sros_4715
BSD: BLASA_2599(ligB)
MMAR: MODMU_2843(ligB) MODMU_3384
PSEA: WY02_25080
PAUT: Pdca_48140(pcaH_2)
ACTN: L083_0820
AFS: AFR_03865
AFO: Afer_2021
PYR: P186_1889
POG: Pogu_1799
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2185230
  Authors
Noda Y, Nishikawa S, Shiozuka K, Kadokura H, Nakajima H, Yoda K, Katayama Y, Morohoshi N, Haraguchi T, Yamasaki M
  Title
Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis.
  Journal
J Bacteriol 172:2704-9 (1990)
DOI:10.1128/JB.172.5.2704-2709.1990

KEGG   ORTHOLOGY: K15065Help
Entry
K15065                      KO                                     

Name
desZ
Definition
3-O-methylgallate 3,4-dioxygenase [EC:1.13.11.-]
Pathway
ko00627  Aminobenzoate degradation
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K15065  desZ; 3-O-methylgallate 3,4-dioxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.-  
     K15065  desZ; 3-O-methylgallate 3,4-dioxygenase
BRITE hierarchy
Other DBs
RN: R04280 R09272
Genes
REU: Reut_B5775
BGE: BC1002_4699
SSY: SLG_19030(desZ)
TaxonomyKoalaUniProt
Reference
  Authors
Abe T, Masai E, Miyauchi K, Katayama Y, Fukuda M
  Title
A tetrahydrofolate-dependent O-demethylase, LigM, is crucial for catabolism of vanillate and syringate in Sphingomonas paucimobilis SYK-6.
  Journal
J Bacteriol 187:2030-7 (2005)
DOI:10.1128/JB.187.6.2030-2037.2005

KEGG   ENZYME: 1.13.11.8Help
Entry
EC 1.13.11.8                Enzyme                                 

Name
protocatechuate 4,5-dioxygenase;
protocatechuate 4,5-oxygenase;
protocatechuic 4,5-dioxygenase;
protocatechuic 4,5-oxygenase;
protocatechuate:oxygen 4,5-oxidoreductase (decyclizing);
protocatechuate:oxygen 4,5-oxidoreductase (ring-opening)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
3,4-dihydroxybenzoate:oxygen 4,5-oxidoreductase (ring-opening)
Reaction(IUBMB)
3,4-dihydroxybenzoate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde [RN:R01632]
Reaction(KEGG)
Substrate
3,4-dihydroxybenzoate [CPD:C00230];
O2 [CPD:C00007]
Product
4-carboxy-2-hydroxymuconate semialdehyde [CPD:C04484]
Comment
Requires Fe2+.
History
EC 1.13.11.8 created 1965 as EC 1.13.1.8, transferred 1972 to EC 1.13.11.8
Pathway
ec00362  Benzoate degradation
ec00624  Polycyclic aromatic hydrocarbon degradation
ec00627  Aminobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04100  protocatechuate 4,5-dioxygenase, alpha chain
K04101  protocatechuate 4,5-dioxygenase, beta chain
Genes
XCC: XCC0804(pcaH) XCC0805(ligA)
XCB: XC_3426 XC_3427
XCA: xcc-b100_3546(ligA) xcc-b100_3547(ligB)
XCP: XCR_0984 XCR_0985
XCV: XCV0913(ligB) XCV0914(ligA)
XAX: XACM_0859(ligB) XACM_0860
XAC: XAC0878(pcaH) XAC0879(ligA)
XCI: XCAW_03701(ligA) XCAW_03702(pcaH)
XCT: J151_01005 J151_01006
XCJ: J158_01002 J158_01003
XOO: XOO3734(pcaH)
XOM: XOO3524(XOO3524) XOO3525(XOO3525)
XOP: PXO_04631
XPH: XppCFBP6546_07115(XppCFBP6546P_07115) XppCFBP6546_07120(XppCFBP6546P_07120)
PPUT: L483_17500
RFO: REIFOR_00545(ligA) REIFOR_00546(ligB)
KKI: KKKWG1_0313(ligB)
HYF: DTO96_100892(ligA_1) DTO96_100893(ligB)
AFQ: AFA_05515 AFA_05520(ligA)
VEI: Veis_1369
LIM: L103DPR2_01497(ligA_1) L103DPR2_01498(ligB_1) L103DPR2_01514(ligA_2) L103DPR2_01515(ligB_2)
LIH: L63ED372_01144(ligA_1) L63ED372_01145(ligB)
HPSE: HPF_08080(ligA1) HPF_08085(ligB1) HPF_08185(ligA2) HPF_08190(ligB2)
AZO: azo2522(ligB1) azo2523(ligA1) azo2537(ligB2) azo2538(ligA2)
BRA: BRADO2341(ligA) BRADO2342(ligB) BRADO2379 BRADO2380(mhpB)
BBT: BBta_2701(ligA) BBta_2702(ligB) BBta_2733 BBta_2734(mhpB)
BRO: BRAD285_4958(ligB) BRAD285_4959(ligA) BRAD285_4995(ligB) BRAD285_4996(ligA)
RPA: RPA1006 RPA1007(mhpB) RPA4701(ligA) RPA4702(ligB)
MMED: Mame_04593(ligB)
SPHP: LH20_03910
SPHR: BSY17_3446(ligB) BSY17_3447(ligA)
BLAS: BSY18_3523(ligA) BSY18_3524(ligB)
AAY: WYH_01045(ligB_1) WYH_01046(ligA_2) WYH_01908(ligA_3) WYH_01909(ligB_2) WYH_03214(ligB_3) WYH_03215(ligA_4)
ADO: A6F68_01079(ligB) A6F68_01080(ligA_1)
TMO: TMO_b0114 TMO_b0115(mhpB)
MAGQ: MGMAQ_2661(ligB) MGMAQ_2662(ligA) MGMAQ_2669(ligA) MGMAQ_2670(ligB)
AUW: AURUGA1_00419(ligA_1) AURUGA1_00420(ligB)
BSD: BLASA_2598(ligA) BLASA_2599(ligB)
MMAR: MODMU_2843(ligB) MODMU_2844(ligA) MODMU_3384
PSEA: WY02_25080
PAUT: Pdca_48140(pcaH_2) Pdca_48150
ACTN: L083_0820
AFS: AFR_03865
AFO: Afer_2021
PYR: P186_1889
POG: Pogu_1799
 » show all
Taxonomy
Reference
1
  Authors
Trippett, S., Dagley, S. and Stopher, D.A.
  Title
The bacterial oxidation of nicotinic acid.
  Journal
Biochem J 76:9 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.8
IUBMB Enzyme Nomenclature: 1.13.11.8
ExPASy - ENZYME nomenclature database: 1.13.11.8
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.8
BRENDA, the Enzyme Database: 1.13.11.8
CAS: 9029-56-5

KEGG   REACTION: R04280Help
Entry
R04280                      Reaction                               

Name
3-O-methylgallate:oxygen 4,5-oxidoreductase (decyclizing)
Definition
3-O-Methylgallate + Oxygen <=> 2-Pyrone-4,6-dicarboxylate + Methanol
Equation
Reaction class
RC00233  C00132_C05616
RC02694  C03671_C05616
Enzyme
1.13.11.8       1.13.11.-
Pathway
rn00627  Aminobenzoate degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K04100  protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8]
K04101  protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
K15065  3-O-methylgallate 3,4-dioxygenase [EC:1.13.11.-]
Other DBs
RHEA: 31130

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