KEGG   ORTHOLOGY: K04118
Entry
K04118                      KO                                     

Name
E1.3.1.62
Definition
pimeloyl-CoA dehydrogenase [EC:1.3.1.62]
Pathway
ko00362  Benzoate degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K04118  E1.3.1.62; pimeloyl-CoA dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.62  pimeloyl-CoA dehydrogenase
     K04118  E1.3.1.62; pimeloyl-CoA dehydrogenase
Other DBs
RN: R05311
GO: 0018515
Genes
REH: H16_B0371(pimC) H16_B0372(pimD) H16_B0383(h16_B0383)
REU: Reut_B4559
RME: Rmet_5529 Rmet_5530
ADN: Alide_3276
ADK: Alide2_1171

KEGG   ENZYME: 1.3.1.62
Entry
EC 1.3.1.62                 Enzyme                                 

Name
pimeloyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
pimeloyl-CoA:NAD+ oxidoreductase
Reaction(IUBMB)
pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+ [RN:R05311]
Reaction(KEGG)
R05311
Substrate
pimeloyl-CoA [CPD:C01063];
NAD+ [CPD:C00003]
Product
6-carboxyhex-2-enoyl-CoA [CPD:C06723];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the benzoate degradation (anaerobic) pathway in bacteria.
History
EC 1.3.1.62 created 2000
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04118  pimeloyl-CoA dehydrogenase
Genes
REH: H16_B0371(pimC) H16_B0372(pimD) H16_B0383(h16_B0383)
REU: Reut_B4559
RME: Rmet_5529 Rmet_5530
ADN: Alide_3276
ADK: Alide2_1171
Reference
1  [PMID:8180704]
  Authors
Gallus C, Schink B.
  Title
Anaerobic degradation of pimelate by newly isolated denitrifying bacteria.
  Journal
Microbiology 140 ( Pt 2):409-16 (1994)
DOI:10.1099/13500872-140-2-409
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.62
IUBMB Enzyme Nomenclature: 1.3.1.62
ExPASy - ENZYME nomenclature database: 1.3.1.62
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.62
BRENDA, the Enzyme Database: 1.3.1.62
CAS: 276682-23-6

KEGG   REACTION: R05311
Entry
R05311                      Reaction                               

Name
pimeloyl-CoA:NAD+ oxidoreductase
Definition
6-Carboxyhexanoyl-CoA + NAD+ <=> 6-Carboxyhex-2-enoyl-CoA + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00052  C01063_C06723
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K04118  pimeloyl-CoA dehydrogenase [EC:1.3.1.62]
Other DBs
RHEA: 19668

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