KEGG ORTHOLOGY: K04166

ORTHOLOGY: K04166

Entry

K04166 KO

Name

AGTR1

Definition

angiotensin II receptor type 1

Pathway

ko04020

Calcium signaling pathway

ko04022

cGMP-PKG signaling pathway

ko04072

Phospholipase D signaling pathway

ko04080

Neuroactive ligand-receptor interaction

ko04261

Adrenergic signaling in cardiomyocytes

ko04270

Vascular smooth muscle contraction

ko04371

Apelin signaling pathway

ko04614

Renin-angiotensin system

ko04924

Renin secretion

ko04925

Aldosterone synthesis and secretion

ko04927

Cortisol synthesis and secretion

ko04933

AGE-RAGE signaling pathway in diabetic complications

ko04934

Cushing syndrome

ko05200

Pathways in cancer

Disease

H00575

Renal tubular dysgenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04020 Calcium signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04072 Phospholipase D signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04022 cGMP-PKG signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04166  AGTR1; angiotensin II receptor type 1
09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    K04166  AGTR1; angiotensin II receptor type 1
   04614 Renin-angiotensin system
    K04166  AGTR1; angiotensin II receptor type 1
   04925 Aldosterone synthesis and secretion
    K04166  AGTR1; angiotensin II receptor type 1
   04927 Cortisol synthesis and secretion
    K04166  AGTR1; angiotensin II receptor type 1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04166  AGTR1; angiotensin II receptor type 1
   04270 Vascular smooth muscle contraction
    K04166  AGTR1; angiotensin II receptor type 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04166  AGTR1; angiotensin II receptor type 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04166  AGTR1; angiotensin II receptor type 1
   04934 Cushing syndrome
    K04166  AGTR1; angiotensin II receptor type 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04166  AGTR1; angiotensin II receptor type 1
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04166  AGTR1; angiotensin II receptor type 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K04166  AGTR1; angiotensin II receptor type 1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Angiotensin
    K04166  AGTR1; angiotensin II receptor type 1

Other DBs

GO:

0001596

TC:	9.A.14.13.1

Genes

HSA:	185(AGTR1)

PTR:	460762(AGTR1)

PPS:	100992718(AGTR1)

GGO:	101128433(AGTR1)

PON:	100461588(AGTR1)

NLE:	100603931(AGTR1)

MCC:	712773(AGTR1)

MCF:	102130940(AGTR1)

CSAB:

103241511(AGTR1)

RRO:	104671550(AGTR1)

RBB:	108518305(AGTR1)

CJC:	100406419(AGTR1)

SBQ:	101037991(AGTR1)

MMU:	11607(Agtr1a) 11608(Agtr1b)

MCAL:

110291663(Agtr1) 110307911

MPAH:

110320654(Agtr1) 110333989

RNO:	24180(Agtr1a) 81638(Agtr1b)

MUN:	110539373 110539375 110563019(Agtr1)

CGE:	100750798(Agtr1) 100755233

NGI:	103737006 103745994(Agtr1)

HGL:	101714068(Agtr1)

CCAN:

109682820(Agtr1)

OCU:	100009164(AGTR1)

TUP:	102469571(AGTR1)

CFA:	403836(AGTR1)

VVP:	112932806(AGTR1)

AML:	109488334(AGTR1)

UMR:	103678133(AGTR1)

UAH:	113254038(AGTR1)

ORO:	101377034(AGTR1)

ELK:

111150851

FCA:	101082936(AGTR1)

PTG:	102968872(AGTR1)

PPAD:

109260696(AGTR1)

AJU:	106975222(AGTR1)

BTA:	281607(AGTR1)

BOM:	102264884(AGTR1)

BIU:	109559421(AGTR1)

BBUB:

102406935(AGTR1)

CHX:	102174163(AGTR1)

OAS:	443107(AGTR1)

SSC:	100519976(AGTR1)

CFR:	102508707(AGTR1)

CDK:	105089509(AGTR1)

BACU:

103001868(AGTR1)

LVE:	103090648(AGTR1)

OOR:	101269573(AGTR1)

DLE:	111179290(AGTR1)

PCAD:

102980831(AGTR1)

ECB:	100059005(AGTR1)

EPZ:	103558752(AGTR1)

EAI:	106829436(AGTR1)

MYB:	102245101(AGTR1)

MYD:	102772519(AGTR1)

MNA:	107544042(AGTR1)

HAI:	109375864(AGTR1)

DRO:	112301009(AGTR1)

PALE:

102895602(AGTR1)

RAY:	107513418(AGTR1)

MJV:	108388618(AGTR1)

LAV:	100659079(AGTR1)

TMU:

101346145

MDO:	100017858(AGTR1)

SHR:	100927259(AGTR1)

PCW:	110204798(AGTR1)

OAA:	100077014(AGTR1)

GGA:	396065(AGTR1)

MGP:	100303701(AGTR1)

CJO:	107318295(AGTR1)

NMEL:

110398297(AGTR1)

APLA:

101804939(AGTR1)

ACYG:

106036265(AGTR1)

TGU:	100224975(AGTR1)

LSR:	110473886(AGTR1)

SCAN:

103815406(AGTR1)

GFR:	102033965(AGTR1)

FAB:	101812375(AGTR1)

PHI:	102112440(AGTR1)

PMAJ:

107209000(AGTR1)

CCAE:

111933486(AGTR1)

CCW:	104693469(AGTR1)

ETL:	114057376(AGTR1)

FPG:	101914397(AGTR1)

FCH:	102052791(AGTR1)

CLV:	102098897(AGTR1)

EGZ:	104127122(AGTR1)

NNI:	104015689(AGTR1)

ACUN:

113483374(AGTR1)

PADL:

103913836(AGTR1)

AAM:	106485864(AGTR1)

ASN:	102369755(AGTR1)

AMJ:	102569750(AGTR1)

PSS:	102455529(AGTR1)

CMY:	102942297(AGTR1)

CPIC:

101953639(AGTR1)

ACS:	100555655(agtr1)

PVT:	110073044(AGTR1)

PBI:

103064286

PMUR:

107284836(AGTR1)

TSR:	106538577(AGTR1)

PMUA:

114597861(AGTR1)

GJA:	107124666(AGTR1)

XLA:	108707736 378523(agtr1.S) 398763(agtr1.L)

XTR:	100170183(agtr1)

NPR:	108797310(AGTR1)

DRE:	100333455(agtr1b) 794575(agtr1a)

SRX:	107709880 107717774 107717851 107722527 107739124

SANH:

107663725 107680245 107681633 107688540

SGH:	107550594 107557561 107576085 107584999 107588039

CCAR:

109051050 109055900 109055910 109068275

IPU:	108273841(agtr1)

PHYP:

113545434(agtr1)

AMEX:

103027188 103027843

EEE:

113584765

TRU:	101065754(agtr1)

TNG:	GSTEN00023936G001

LCO:	104937220(agtr1)

NCC:	104964950(agtr1)

MZE:	101480357(agtr1)

ONL:	100702961(agtr1)

OLA:	101170058(agtr1)

XMA:	102227070(agtr1)

XCO:	114137076(agtr1)

PRET:

103456547(agtr1)

CVG:	107096468(agtr1)

NFU:	107382808(agtr1)

KMR:	108230521(agtr1)

ALIM:

106513363(agtr1)

AOCE:

111579241(agtr1)

CSEM:

103377268(agtr1)

POV:	109629586(agtr1)

LCF:	108881687(agtr1)

SDU:	111237875(agtr1)

SLAL:

111656273(agtr1)

HCQ:	109519485(agtr1)

BPEC:

110155322 110170085(agtr1)

MALB:

109961497(agtr1)

SASA:

106579762 106590686

OTW:

112216162

SALP:

112073876 112074818

ELS:	105026597(agtr1)

SFM:	108934912(agtr1)

PKI:	111850479(agtr1)

LCM:	102347667(AGTR1)

CMK:	103184450(agtr1)

RTP:

109915788

» show all

Reference

PMID:7688227

Authors

Ji H, Sandberg K, Zhang Y, Catt KJ

Title

Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor.

Journal

Biochem Biophys Res Commun 194:756-62 (1993)
DOI:10.1006/bbrc.1993.1886

Sequence

[xla:398763]

Reference

PMID:1567413

Authors

Bergsma DJ, Ellis C, Kumar C, Nuthulaganti P, Kersten H, Elshourbagy N, Griffin E, Stadel JM, Aiyar N

Title

Cloning and characterization of a human angiotensin II type 1 receptor.

Journal

Biochem Biophys Res Commun 183:989-95 (1992)
DOI:10.1016/S0006-291X(05)80288-8

Sequence

[hsa:185]

ORTHOLOGY: K04167

Entry

K04167 KO

Name

AGTR2

Definition

angiotensin II receptor type 2

Pathway

ko04080

Neuroactive ligand-receptor interaction

ko04261

Adrenergic signaling in cardiomyocytes

ko04614

Renin-angiotensin system

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04167  AGTR2; angiotensin II receptor type 2
09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    K04167  AGTR2; angiotensin II receptor type 2
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04167  AGTR2; angiotensin II receptor type 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04167  AGTR2; angiotensin II receptor type 2
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Angiotensin
    K04167  AGTR2; angiotensin II receptor type 2

Other DBs

GO:

0004945

Genes

HSA:	186(AGTR2)

PTR:	742608(AGTR2)

PPS:	100993247(AGTR2)

GGO:	101129696(AGTR2)

PON:	100454423(AGTR2)

NLE:	100605755(AGTR2)

MCC:	709513(AGTR2)

MCF:	102127892(AGTR2)

CSAB:

103247407(AGTR2)

RRO:	104671811(AGTR2)

RBB:	108535721(AGTR2)

CJC:	100405479(AGTR2)

SBQ:	101040796(AGTR2)

MMU:	11609(Agtr2)

MCAL:

110287422(Agtr2)

MPAH:

110313525(Agtr2)

RNO:	24182(Agtr2)

MUN:	110543144(Agtr2)

CGE:	113830710(Agtr2)

NGI:	103749076(Agtr2)

HGL:	101704847(Agtr2)

CCAN:

109675668(Agtr2)

OCU:	100009329(AGTR2)

TUP:	102502405(AGTR2)

CFA:	403835(AGTR2)

VVP:	112910724(AGTR2)

AML:	100474021(AGTR2)

UMR:	103677708(AGTR2)

UAH:	113241213(AGTR2)

ORO:	101364925(AGTR2)

ELK:

111157307

FCA:	101080516(AGTR2)

PTG:	102950390(AGTR2)

PPAD:

109250795(AGTR2)

AJU:	106966729(AGTR2)

BTA:	407157(AGTR2)

BOM:	102279284(AGTR2)

BBUB:

102402520(AGTR2)

CHX:	102189288(AGTR2)

OAS:	443335(AGTR2)

SSC:	733586(AGTR2)

CFR:	102523478(AGTR2)

CDK:	105093917(AGTR2)

BACU:

103007585(AGTR2)

LVE:	103072424(AGTR2)

OOR:	101275662(AGTR2)

DLE:	111169060(AGTR2)

PCAD:

102990833(AGTR2)

ECB:	100053878(AGTR2)

EPZ:	103541940(AGTR2)

EAI:	106824864(AGTR2)

MYB:	102260858(AGTR2)

MYD:	102755965(AGTR2)

MNA:	107543671(AGTR2)

HAI:	109378069(AGTR2)

DRO:	112303803 112303871

PALE:

102898855(AGTR2)

RAY:	107517857(AGTR2)

MJV:	108386744(AGTR2)

LAV:	100666379(AGTR2)

TMU:

101358504

MDO:	100010566(AGTR2)

SHR:	100921903(AGTR2)

PCW:	110192378(AGTR2)

GGA:	428708(AGTR2)

MGP:	100545892(AGTR2)

CJO:	107312628(AGTR2)

NMEL:

110403344(AGTR2)

APLA:

101801294(AGTR2)

ACYG:

106037479(AGTR2)

TGU:	100225565(AGTR2)

LSR:	110480463(AGTR2)

SCAN:

103816409(AGTR2)

GFR:	102037311(AGTR2)

FAB:	101812756(AGTR2)

PHI:	102108224(AGTR2)

PMAJ:

107203745(AGTR2)

CCAE:

111928643(AGTR2)

CCW:	104694403(AGTR2)

ETL:	114065345(AGTR2)

FPG:	101919126(AGTR2)

FCH:	102051411(AGTR2)

CLV:	102097140(AGTR2)

EGZ:	104124280(AGTR2)

NNI:	104012966(AGTR2)

ACUN:

113480053(AGTR2)

PADL:

103923355(AGTR2)

AAM:	106486613(AGTR2)

ASN:	102383790(AGTR2)

AMJ:	102565205(AGTR2)

PSS:	102456998(AGTR2)

CMY:	102935059(AGTR2)

CPIC:

101947609(AGTR2)

ACS:	100565925(agtr2)

PVT:	110080135(AGTR2)

PBI:	103061010(AGTR2)

PMUR:

107303217(AGTR2)

TSR:	106544203(AGTR2)

PMUA:

114589166(AGTR2)

GJA:	107114688(AGTR2)

XLA:	444403(agtr2.L)

XTR:	779906(agtr2)

NPR:	108787216(AGTR2)

DRE:	503772(agtr2)

SRX:	107732613 107733228

SANH:

107672423 107680405

SGH:	107592269 107597233

CCAR:

109090312 109090436

PHYP:

113524216

AMEX:

103035052 103038562

EEE:	113574167(agtr2) 113591060

TRU:

101068989

TNG:	GSTEN00029336G001

LCO:

NCC:

MZE:

ONL:

OLA:

XMA:

XCO:

PRET:

103470918(agtr2)

CVG:

NFU:

KMR:

ALIM:

AOCE:

CSEM:

POV:

LCF:

SDU:

SLAL:

HCQ:

BPEC:

MALB:

SASA:

100380342(agtr2) 106568033

OTW:

112228715

SALP:

111950882

ELS:	105026963(agtr2)

SFM:	108920029 108925417

PKI:	111855502(agtr2)

LCM:	102361841(AGTR2)

RTP:

109916234

» show all

Reference

PMID:15539617

Authors

Wruck CJ, Funke-Kaiser H, Pufe T, Kusserow H, Menk M, Schefe JH, Kruse ML, Stoll M, Unger T

Title

Regulation of transport of the angiotensin AT2 receptor by a novel membrane-associated Golgi protein.

Journal

Arterioscler Thromb Vasc Biol 25:57-64 (2005)
DOI:10.1161/01.ATV.0000150662.51436.14

Sequence

[mmu:11609]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Drug (5)   
   KEGG DRUG (5)   
Gene (248)   
   KEGG GENES (151)   
   KEGG MGENES (35)   
   RefGene (61)   
   OC (1)   
Protein sequence (72)   
   UniProt (69)   
   SWISS-PROT (3)   
Literature (1)   
   PubMed (1)   
All databases (335)   

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