KEGG ORTHOLOGY: K04228

ORTHOLOGY: K04228

Entry

K04228                      KO

Symbol

AVPR2

Name

arginine vasopressin receptor 2

Pathway

map04072

Phospholipase D signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04962

Vasopressin-regulated water reabsorption

Disease

H00252

Congenital nephrogenic diabetes insipidus

H01294

Nephrogenic syndrome of inappropriate antidiuresis

H01682

Syndrome of inappropriate antidiuretic hormone secretion

H01683

Disorders of antidiuretic hormone (ADH) secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04228  AVPR2; arginine vasopressin receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04228  AVPR2; arginine vasopressin receptor 2
   04081 Hormone signaling
    K04228  AVPR2; arginine vasopressin receptor 2
09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K04228  AVPR2; arginine vasopressin receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04228  AVPR2; arginine vasopressin receptor 2
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Vasopressin
    K04228  AVPR2; arginine vasopressin receptor 2

Other DBs

GO:

0005000

TC:	9.A.14.10.3

Genes

HSA:	554(AVPR2)

PTR:	742565(AVPR2)

PPS:	100971355(AVPR2)

GGO:	101128967(AVPR2)

PON:	100441909(AVPR2)

PPYG:

129024553(AVPR2)

NLE:	100595937(AVPR2)

HMH:	116464707(AVPR2)

SSYN:

129475623(AVPR2)

MCC:	697763(AVPR2)

MCF:	102128949(AVPR2)

MTHB:

126945474

MNI:	105467316(AVPR2)

CSAB:

103232806(AVPR2)

CATY:

105598724(AVPR2)

PANU:

100137253(AVPR2)

TGE:	112615091(AVPR2)

MLEU:

105555361(AVPR2)

RRO:	104661171(AVPR2)

RBB:	108535070 108535071(AVPR2)

TFN:	117063452(AVPR2)

PTEH:

111534061(AVPR2)

CANG:

105521628(AVPR2)

CJC:	100411175(AVPR2)

SBQ:	101035137(AVPR2)

CIMI:

108294740(AVPR2)

ANAN:

105707109(AVPR2)

CSYR:

103274084(AVPR2)

MMUR:

105867320(AVPR2)

LCAT:

123628469(AVPR2)

PCOQ:

105824548(AVPR2)

OGA:	100949961(AVPR2)

MMU:	12000(Avpr2)

MCAL:

110286545(Avpr2)

MPAH:

110313418(Avpr2)

RNO:	25108(Avpr2)

MCOC:

116073322(Avpr2)

ANU:	117695291(Avpr2)

ASYL:

127674739(Avpr2)

MUN:	110560452(Avpr2)

CGE:	100768840(Avpr2)

MAUA:

101832425(Avpr2)

PROB:

127217385(Avpr2)

PLEU:

114706212(Avpr2)

MORG:

121437270 121440314

MFOT:

126490226

AAMP:

119805513(Avpr2)

NGI:	103731205(Avpr2)

HGL:	101725573(Avpr2)

CPOC:

100712605(Avpr2)

DORD:

106000127(Avpr2)

DSP:	122097061(Avpr2)

DMER:

138839979(Avpr2)

PLOP:

125343836(Avpr2)

NCAR:

124972331

MMMA:

107160267(Avpr2)

ITI:	101969735(Avpr2)

OCU:

100352555

OPI:	101522604(AVPR2)

TUP:	102502524(AVPR2)

GVR:	103595088(AVPR2)

CFA:	403804(AVPR2)

CLUD:

112668378(AVPR2)

VVP:	112911486(AVPR2)

VLG:	121483316(AVPR2)

NPO:	129518391(AVPR2)

AML:	100482540(AVPR2)

UMR:	121102044(AVPR2)

UAR:	123786236(AVPR2)

ELK:

111139174

LLV:

125091315

MPUF:

101682703(AVPR2)

MNP:	132007499(AVPR2)

MLK:	131820843(AVPR2)

NVS:	122896932(AVPR2)

ORO:	101380239(AVPR2)

EJU:	114201627(AVPR2)

ZCA:	113930995(AVPR2)

MLX:	118014814(AVPR2)

NSU:	110574305(AVPR2)

LWW:	102749876(AVPR2)

FCA:	101082135(AVPR2)

PYU:	121025092(AVPR2)

PCOO:

112871213(AVPR2)

PBG:	122477906(AVPR2)

PVIV:

125159310(AVPR2)

LRUF:

124525820

LGF:	123595420(AVPR2)

AJU:

113597384

PPAD:

109259834 109259844

PUC:

125931432

HHV:	120221728(AVPR2)

BTA:	281642(AVPR2)

BOM:	102276704(AVPR2)

BBUB:

102409873(AVPR2)

CHX:	102190593(AVPR2)

OAS:	100528011(AVPR2)

BTAX:

128070527(AVPR2)

CSUM:

138071523(AVPR2)

ODA:	120881830(AVPR2)

CCAD:

122435276(AVPR2)

MREE:

136154094(AVPR2)

OVR:	110136261(AVPR2)

MBEZ:

129535173(AVPR2)

SSC:	397462(AVPR2)

CFR:	102509646(AVPR2)

CBAI:

105076075(AVPR2)

CDK:	105098710(AVPR2)

VPC:	102546047(AVPR2)

BMUS:

118888786(AVPR2)

LVE:	103069934(AVPR2)

OOR:	101279287(AVPR2)

LALB:

132513627(AVPR2)

GMF:	115849318(AVPR2)

DLE:	111170616(AVPR2)

PCAD:

102977461(AVPR2)

PSIU:

116747373(AVPR2)

PPHC:

136142645(AVPR2)

NASI:

112406822(AVPR2)

ECB:	100059066(AVPR2)

EPZ:	103544847(AVPR2)

EAI:	106825609(AVPR2)

MYB:	102259589(AVPR2)

MYD:	102758757(AVPR2)

MMYO:

118653877(AVPR2)

MLF:	102422064(AVPR2)

MDT:	132224751(AVPR2)

PKL:	118714690(AVPR2)

EFUS:

103302218(AVPR2)

MNA:	107538807(AVPR2)

DRO:	112296353(AVPR2)

SHON:

118994279(AVPR2)

AJM:	119053114(AVPR2)

PDIC:

114505728(AVPR2)

PHAS:

123823121(AVPR2)

MMF:	118635924(AVPR2)

PPAM:

129074361(AVPR2)

HAI:	109394327(AVPR2)

RFQ:	117028203(AVPR2)

PALE:

102893664(AVPR2)

PGIG:

120605895(AVPR2)

PVP:	105302524(AVPR2)

RAY:	107517751(AVPR2)

MJV:	108407470(AVPR2)

TOD:	119246481(AVPR2)

SARA:

101548653(AVPR2)

SFUM:

130017923(AVPR2)

SETR:

125998952(AVPR2)

LAV:	100677315(AVPR2)

TMU:

101349004

ETF:	101663694(AVPR2)

DNM:

101431216

GAS:	123253397(AVPR2)

SHR:	100922593(AVPR2)

AFZ:

127542617

PCW:	110201513(AVPR2)

TVP:	118833082(AVPR2)

PBRV:

138177317(AVPR2)

MLAO:

141500490(AVPR2)

OAA:	100091389(AVPR2)

TACU:

119929866(AVPR2)

GGA:	427860(AVPR2)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:	100232797(VT1) 115491955

LSR:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

GFR:

FAB:

OMA:	130248484 130266026

PHI:	102104327 102111850(AVPR2)

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:

ZLE:	135457700 135460815

ACHL:

SVG:

MMEA:

HRT:

SATI:

CCIC:

FPG:

FCH:

CCRI:

NNT:

SHAB:

ACUN:

TALA:

ACHC:

HALD:

HLE:

AGEN:

HHAR:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

AVIT:

BRHI:

EGZ:

NNI:

PCRI:

PCAO:

PADL:

AFOR:

FGA:

GSTE:

CBOY:

CLV:

CNIC:

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

CVF:

RTD:

CRID:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:

AMJ:

CPOO:

GGN:

PSS:

CMY:

CCAY:

125628377(AVPR2) 125630715

DCC:	119843588 119847317(AVPR2)

CPIC:

101945660 101946394(AVPR2)

TST:

117868415

CABI:

116832822 116833502(AVPR2)

MRV:	120386748 120388583(AVPR2)

ACS:	100562801(avpr2)

ASAO:

132766533(AVPR2) 132776238

PVT:	110078656(AVPR2) 110082143

SUND:

121920507(AVPR2) 121932320

PBI:	103051229(AVPR2) 103064888

PMUR:

107284198(AVPR2)

CTIG:

120301439(AVPR2)

TSR:	106552956(AVPR2)

PGUT:

117675358(AVPR2)

PCAE:

139310909(AVPR2)

APRI:

131192433(AVPR2)

PTEX:

113443409(AVPR2)

NSS:	113417798(AVPR2)

VKO:	123019811 123029956(AVPR2)

PMUA:

114587913(AVPR2) 114605958

PRAF:

128405357(AVPR2) 128421647

ZVI:	118091499 118097798(AVPR2)

HCG:	128328456 128347859(AVPR2)

GJA:	107113884 107117061(AVPR2)

STOW:

125428089(AVPR2) 125434418

EMC:	129336177 129346354(AVPR2)

XLA:	108700007(avpr2.S) 108704793(avpr2.L) 108713125

XTR:	100487051(avpr2) 100489955(avpr2.2)

NPR:	108784478(AVPR2)

RTEM:

120913209(AVPR2)

ACAT:

141108576(AVPR2)

BBUF:

120977646(AVPR2) 120985614

BGAR:

122925841 122946391(AVPR2)

DTC:	141101608(AVPR2)

PWL:	138260919(AVPR2) 138288537

MUO:	115463512(AVPR2) 115478306

GSH:	117363401(AVPR2) 117366412

DRE:	100004053(avpr2l) 100007585(avpr2aa) 100151502(avpr2ab) 100534787(avpr2b.1)

SRX:	107713506 107716149 107725532 107737524 107737642 107741337 107744926 107750238

SANH:

107657032 107664848 107667040 107672000 107672002 107673055 107687451 107695886

SGH:	107560910 107562472 107579128 107584469 107588672 107590222 107591070 107599421

CCAR:

109075088 109078712 109081501 109083295 109088587 109091509 109104290

CAUA:

113048155 113050476 113062591 113065528 113065548 113068939 113069108 113094717 113096033

CGIB:

127944357 127944466 127956928 127960019 127974795 128011156 128012043 128015844

PTET:

122328395(avpr2ab) 122328959(avpr2aa) 122342893(avpr2l) 122347028(avpr2b.1)

LROH:

127154271(avpr2aa) 127155028(avpr2ab) 127163727(avpr2l) 127166388(avpr2b.1)

GRF:	141290728 141290763(avpr2ab) 141290883(avpr2aa) 141333131(avpr2l) 141346757(avpr2b.1)

OMC:	131532038(avpr2ab) 131532066(avpr2aa) 131539061(avpr2l) 131542557(avpr2b.1)

PPRM:

120462811(avpr2aa) 120463739(avpr2ab) 120476544 120477015 120491422(si:dkey-178o16.4)

RKG:	130072280(avpr2l) 130081710(avpr2ab) 130087426(avpr2b.1) 130102207(avpr2aa)

MAMB:

125244959(avpr2l) 125260034(avpr2ab) 125260381(avpr2aa) 125273453(avpr2b.1)

CIDE:

127504689 127505381 127510879 127514493

CERY:

137009474(avpr2ab) 137009683(avpr2aa) 137011010(avpr2b.1) 137023937(avpr2l)

MASI:

127419448 127419532 127420058 127420085 127435477 127449119

TROS:

130544971(avpr2aa) 130545481(avpr2ab) 130547492(avpr2l) 130557346(avpr2b.1)

TDW:	130409695(avpr2aa) 130409707(avpr2ab) 130420607(avpr2l) 130424613(avpr2b.1)

MANU:

129431105(avpr2aa) 129431124(avpr2ab) 129431707(avpr2l) 129450419(avpr2b.1)

PDAB:

135749806(avpr2l) 135770121(avpr2b.1) 135775513(avpr2aa) 135775670(avpr2ab)

IPU:	108272099(avpr2b.1) 108275493(avpr2aa) 108275514(avpr2ab)

IFU:	128614759(avpr2b.1) 128619233(avpr2ab) 128619562(avpr2aa)

PHYP:

113530299 113530452 113534048

SMEO:

124390793(avpr2b.1) 124398593(avpr2aa) 124399250(avpr2ab)

TFD:	113642021(avpr2aa) 113643112(avpr2b.1) 113658293(avpr2ab)

TVC:	132843987(avpr2b.1) 132861830(avpr2aa) 132862487(avpr2ab)

CGAR:

128509931(avpr2aa) 128510111(avpr2ab) 128526869(avpr2b.1)

NGRA:

132896521(avpr2aa) 132896929(avpr2ab)

TRN:	134316354(avpr2b.1) 134333982(avpr2aa) 134334011(avpr2ab)

AMEX:

103033689(avpr2aa) 103036026(avpr2b.1) 103045451(avpr2ab)

CMAO:

118807604(si:dkey-178o16.4) 118822414(avpr2ab) 118822862(avpr2aa)

EEE:	113570937 113581391 113587971 113588002

CHAR:

105894120(avpr2ab) 105897269 105902592(avpr2l) 105909949(avpr2ba)

SPIL:

134061693 134061696 134087639 134088239(avpr2ab) 134092154(avpr2b.1)

TRU:	101063096 101063562 101074372

TFS:	130524562(avpr2b.1) 130529790 130530158

TNG:	GSTEN00014143G001 GSTEN00023340G001 GSTEN00028117G001

LCO:	104921970 104928361 104932798 104933451 109138873

NCC:	104941406 104946224(avpr2) 104952562 104963568 104965399

TBEN:

117475594(si:dkey-178o16.4) 117483102(avpr2l) 117483470 117489709 117494386(avpr2aa)

CGOB:

115008454 115010546 115010630 115028647

PGEO:

117446935 117446957(avpr2b.1) 117449550 117449991(avpr2aa) 117468417(avpr2l)

GACU:

117537363 117542072(avpr2aa) 117543715 117543809(si:dkey-178o16.4) 117551110 117558255(avpr2l)

EMAC:

134863564 134866692 134879525(avpr2l) 134882966(avpr2b.1) 134883043

ELY:	117249400(avpr2l) 117256536 117257531(si:dkey-178o16.4) 117258614 117258879(avpr2aa)

EFO:	125883199(avpr2l) 125889563 125890238(avpr2b.1) 125891166 125891702

PLEP:

121947193 121947299 121950478 121950543(avpr2ba) 121961435(avpr2l)

SLUC:

116036467(si:dkey-178o16.4) 116039203(avpr2aa) 116039786(avpr2l) 116041737 116059357

ECRA:

117938469(avpr2l) 117942925(si:dkey-178o16.4) 117947771(avpr2aa) 117948112

ESP:	116673260 116687331 116688405 116692342 116692996

PFLV:

114550509 114553604 114553750 114558409(avpr2) 114558483

GAT:	120817879(avpr2l) 120829100(avpr2aa) 120829372(avpr2ab) 120834863(si:dkey-178o16.4)

PPUG:

119194258(avpr2b.1) 119222431 119223236

AFB:	129099602 129100421 129105628(avpr2b.1) 129105648 129112841(avpr2l)

CLUM:

117730645(si:dkey-178o16.4) 117731290 117733214 117734068

PSWI:

130199295 130199777 130208304(avpr2b.1)

CANA:

137796050(avpr2b.1) 137796252 137800187 137800312

CVE:	137870652(avpr2b.1) 137874067 137877451(avpr2l) 137889373(avpr2aa) 137889799

MSAM:

119885436(si:dkey-178o16.4) 119886130 119905093 119906045(avpr2aa) 119918244(avpr2l)

SCHU:

122866921 122882573 122882999 122885622(avpr2b.1)

CUD:	121505768(avpr2l) 121507050 121516974 121516994 121528355(si:dkey-178o16.4)

SPUL:

138589428 138589513 138599336(avpr2l) 138605555 138605573(avpr2b.1)

LMIX:

132956794(avpr2l) 132977715(avpr2b.1) 132977747 132989214 132990119

ALAT:

119020518 119021251 119022137 119022690 119032372(avpr2l)

ASTR:

137595459 137595550(avpr2b.1) 137606701 137606888

MZE:	101467015 101471235 101474372 101475676

ONL:	100692153 100698829 100707194 102080933

OAU:	116309194 116314020(si:dkey-178o16.4) 116325839(avpr2aa) 116333871

OLA:	100529180(avpr2) 101156883(nft-vtr) 101170270

OML:	112145178(si:dkey-178o16.4) 112159343 112159763

CSAI:

133424591(avpr2l) 133449455(avpr2b.1) 133457209(avpr2aa)

XMA:	102219134 102222176 102229923 102233781 102235889

XCO:	114135719 114135784 114140722 114144727 114161075

XHE:	116710994 116711053 116717871 116726939 116736900

PRET:

103459542 103465256 103465520 103467324(avpr2) 103467895

PFOR:

103129505 103130895 103141160(avpr2) 103143207 103147322

PLAI:

106935734(avpr2) 106955438 106960389 106963884

PMEI:

106905536 106914957(avpr2) 106930023 106931996 106932960

GAF:	122826711(avpr2l) 122833727 122834708 122835353 122837664

PPRL:

129355550(avpr2b.1) 129358384 129372519 129375581(avpr2l) 129377084

CVG:	107082341 107086747(avpr2) 107088756 107094007 107098425

CTUL:

119776655 119782160 119783615(si:dkey-178o16.4) 119795745(avpr2l) 119799380

GMU:	124856142 124856405(avpr2b.1) 124861119 124873287 124883413(avpr2l)

NFU:	107384391 107385698 107390371 107390855(avpr2)

KMR:	108230689(avpr2ab) 108235770 108240974(avpr2l) 108244611(avpr2aa) 108247584(si:dkey-178o16.4)

ALIM:

106518019 106518250 106523524 106525159(avpr2) 106531877

NWH:	119412311(avpr2ba) 119412549 119416588(avpr2ab) 119416978(avpr2aa) 119428264(avpr2l)

AOCE:

111563505(avpr2l) 111564474(avpr2ab) 111566144(avpr2b.1) 111566633 111576519(avpr2aa)

EJA:	138192999 138194647 138201242 138206566(avpr2b.1)

BFRE:

138615321 138626303 138627132(avpr2l) 138630202(avpr2b.1) 138634769

MCEP:

125000066(avpr2l) 125006100 125007020 125007242(avpr2b.1) 125022400

CSEM:

103384583(avpr2) 103385210 103385939 103386276

POV:	109628968 109629056 109630525 109641617

SSEN:

122768153 122768712(avpr2b.1) 122776710 122777617

SSOE:

131460753(avpr2b.1) 131461317 131468365 131468432

HHIP:

117761688(si:dkey-178o16.4) 117762307 117764271 117764773

HSP:	118105247 118105272(avpr2b.1) 118110393 118110446(avpr2aa)

PPLT:

128425341 128441815 128442976(avpr2aa) 128460619(avpr2b.1)

SMAU:

118308893(avpr2b.1) 118310087 118316972 118317594

LCF:	108875477 108876513 108881482 108887381 108898885

SDU:	111219087 111221550 111221685 111234877

SLAL:

111644189 111653187 111663636 111667870 111670753

XGL:	120782906(si:dkey-178o16.4) 120803298 120803374 120803889(avpr2l) 120807546

HCQ:	109520229 109522502

SSCV:

125976896 125977361(avpr2b.1) 125988830(avpr2aa) 125989503

SBIA:

133505763 133507312(avpr2b.1)

PEE:	133402516(avpr2aa) 133408694(avpr2b.1)

PTAO:

133478730(avpr2aa) 133483416(avpr2b.1)

BPEC:

110155853 110164571 110168409 110170211 110175823(avpr2)

ENY:	140362565 140363441(avpr2aa) 140365466 140366063 140368018(avpr2l)

MALB:

109956119 109972170

BSPL:

114855584 114856057(avpr2b.1) 114859146(avpr2aa) 114862622(avpr2l)

SJO:	128355081(avpr2b.1) 128355612 128357668 128357783 128385359(avpr2l)

SSCO:

133977475(avpr2b.1) 133977843 133987198 133987461 134004414(avpr2l)

GMH:	115541039 115551763 115556583

SASA:

106565540 106565942 106567019 106572707 106582781 106583146 106593407 106597533 106598106

STRU:

115149867 115150864 115165478 115167817 115188421 115188448 115207559 115207848

OTW:	112215238 112217455 112221673 112240705(avpr2l) 112255463 112255491 112262546

OMY:	110490794 110491941 110494308 110495193 110500987 110527881 110528128 110531244

OGO:	124003195(avpr2b.1) 124004370 124016907 124019708 124019709 124032304 124046115

ONE:	115102679 115124849 115143160 115143758 115145584 115145939

OKI:	109869858 109876873 109877584 109890176 109891569 109898062 109904532 109908323 116370631

OKE:	118360133 118370711 118388579 118389456(avpr2b.1) 118399774 118400081 127919844 127926680

OMM:	135503995 135528508 135532683(avpr2l) 135539970 135540218 135541082 135541131

OCLA:

139368394 139369883 139371070 139392715 139392716 139404671 139414262 139414347 139417377

SALP:

111966655 111970604 111970627 111972094 111976241 112078652

SNH:	120024881 120025275 120032099(avpr2l) 120058809 120060625 120064552 120065684

CCLU:

121537871 121546753 121559115(avpr2l) 121575245 121575867(avpr2b.1) 121578528 121578677 123490764

ELS:	105013522(avpr2) 105024898

OEP:	134018224 134018562 134022120 134029698 134037618(avpr2l)

SFM:	108918497 108936903 108939418 108942249

PKI:	111837546 111846163 111855150

AANG:

118207818 118207963 118210599(avpr2ab) 118211140 118232122(avpr2l)

AROT:

135234276 135234375 135238123 135238450 135259897(avpr2l)

CCOG:

133110032 133119328 133135092(avpr2l) 133138471 133138747 133141444

LOC:	102682163 102691518 102698801 102698998

PSPA:

121298337(si:dkey-178o16.4) 121319046 121319138 121328478

ARUT:

117411751 117412522 117414619 117419705

PSEX:

120533594 120540362(si:dkey-178o16.4) 120541985(avpr2ab)

LCM:	102353216(AVPR2) 102364818

RTP:	109922991(avpr2b.1)

CPLA:

122559417 122559418

HOC:	132824774 132824811

LERI:

129706221(avpr2b.1)

PMRN:

116942321 116949433

LRJ:	133342560 133349519 133349595

BBEL:

LPIC:

FAS:

DAM:

AGRG:

OTU:

DMK:

LSM:

TCF:

VDE:

VJA:

CVS:

LPOL:

NAI:	NECAME_15399

LSAX:

GAE:

CVN:

MMER:

MAEA:

Reference

PMID:19440390

Authors

Boselt I, Rompler H, Hermsdorf T, Thor D, Busch W, Schulz A, Schoneberg T

Title

Involvement of the V2 vasopressin receptor in adaptation to limited water supply.

Journal

PLoS One 4:e5573 (2009)
DOI:10.1371/journal.pone.0005573

Sequence

[hsa:554]

All links

Ontology (2)   
   GO (1)   
   TC (1)   
Gene (215)   
   MGENES (145)   
   RefGene (67)   
   OC (3)   
All databases (217)   

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