KEGG   ORTHOLOGY: K04234
Entry
K04234                      KO                                     
Symbol
F2RL1, PAR2
Name
coagulation factor II (thrombin) receptor-like 1
Pathway
map04080  Neuroactive ligand-receptor interaction
map04750  Inflammatory mediator regulation of TRP channels
map05143  African trypanosomiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
 09150 Organismal Systems
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05143 African trypanosomiasis
    K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Peptide
   Thrombin
    K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
Other DBs
GO: 0015057
TC: 9.A.14.13.12
Genes
HSA: 2150(F2RL1)
PTR: 461800(F2RL1)
PPS: 130540439(F2RL1)
GGO: 101146046(F2RL1)
PPYG: 129037521(F2RL1)
NLE: 100579568(F2RL1)
HMH: 116471089(F2RL1)
SSYN: 129493273(F2RL1)
MCC: 707479(F2RL1)
MCF: 102137513(F2RL1)
MTHB: 126957591
MNI: 105475116(F2RL1)
CSAB: 103223368(F2RL1)
CATY: 105599188(F2RL1)
PANU: 101011888(F2RL1)
TGE: 112626193(F2RL1)
MLEU: 105551186(F2RL1)
RRO: 104653742(F2RL1)
RBB: 108513086(F2RL1)
TFN: 117065285(F2RL1)
PTEH: 111544499(F2RL1)
CANG: 105524108(F2RL1)
CJC: 100399992(F2RL1)
SBQ: 101029611(F2RL1)
CIMI: 108303736(F2RL1)
ANAN: 105723888(F2RL1)
CSYR: 103271064(F2RL1)
MMUR: 105856538(F2RL1)
LCAT: 123648569(F2RL1)
PCOQ: 105826567(F2RL1)
OGA: 100941227(F2RL1)
MMU: 14063(F2rl1)
MCAL: 110308552(F2rl1)
MPAH: 110329201(F2rl1)
RNO: 116677(F2rl1)
MCOC: 116083662(F2rl1)
ANU: 117700351(F2rl1)
MUN: 110551086(F2rl1)
CGE: 100757860(F2rl1)
MAUA: 101844436(F2rl1)
PROB: 127221090(F2rl1)
PLEU: 114694697(F2rl1)
MORG: 121455613(F2rl1)
MFOT: 126508583
AAMP: 119810357(F2rl1)
NGI: 103752277(F2rl1)
HGL: 101708898(F2rl1) 101718058
CPOC: 100719602(F2rl1)
CCAN: 109701104(F2rl1)
DORD: 105992389(F2rl1)
DSP: 122117165(F2rl1)
PLOP: 125367749(F2rl1)
NCAR: 124987041
MMMA: 107152376(F2rl1)
OCU: 100350303
OPI: 101527647(F2RL1)
TUP: 102485462(F2RL1)
GVR: 103604129(F2RL1)
CFA: 488940(F2RL1)
CLUD: 112653186(F2RL1)
VVP: 112919595(F2RL1)
VLG: 121488641(F2RL1)
NPO: 129515897 129521075(F2RL1)
AML: 100483212(F2RL1)
UMR: 103663553
UAH: 113255187(F2RL1)
UAR: 123791555(F2RL1)
ELK: 111148419
LLV: 125100927
MPUF: 101690048(F2RL1)
MNP: 132028744(F2RL1)
MLK: 131832375(F2RL1)
NVS: 122918380(F2RL1)
ORO: 101364052(F2RL1)
EJU: 114217552(F2RL1)
ZCA: 113929863(F2RL1)
MLX: 118016489(F2RL1)
NSU: 110589511(F2RL1)
LWW: 102737489(F2RL1)
FCA: 101082879(F2RL1)
PCOO: 112861377(F2RL1)
PBG: 122490022(F2RL1)
PVIV: 125158927(F2RL1)
LRUF: 124518268
PTG: 102960149(F2RL1)
PPAD: 109274969(F2RL1)
PUC: 125935759
AJU: 106974825
HHV: 120240715(F2RL1)
BTA: 526525(F2RL1)
BOM: 102271773(F2RL1)
BIU: 109564650(F2RL1)
BBUB: 102396846(F2RL1)
BBIS: 104994143(F2RL1)
CHX: 102187771(F2RL1)
OAS: 101106266(F2RL1)
BTAX: 128054640(F2RL1)
CCAD: 122442990(F2RL1) 122455219
MBEZ: 129562956(F2RL1)
SSC: 100519703(F2RL1)
CFR: 102520615(F2RL1)
CBAI: 105064363(F2RL1)
CDK: 105084811(F2RL1)
VPC: 102545080(F2RL1)
BACU: 103006000(F2RL1)
LVE: 103077744(F2RL1)
OOR: 101278562(F2RL1)
DLE: 111162980(F2RL1)
PCAD: 102987653(F2RL1)
PSIU: 116752056(F2RL1)
NASI: 112391430(F2RL1)
ECB: 100073277(F2RL1)
EPZ: 103540012(F2RL1)
EAI: 106824052(F2RL1)
MYB: 102249464(F2RL1)
MYD: 102755239(F2RL1)
MMYO: 118656193(F2RL1)
MLF: 102421609(F2RL1)
MDT: 132233509(F2RL1)
PKL: 118703049(F2RL1)
EFUS: 103305206(F2RL1)
MNA: 107531206(F2RL1)
DRO: 112307517(F2RL1)
SHON: 118977344(F2RL1)
AJM: 119048155(F2RL1)
PDIC: 114499533(F2RL1)
PHAS: 123824884(F2RL1)
MMF: 118642559(F2RL1)
PPAM: 129074450(F2RL1)
HAI: 109381885(F2RL1)
RFQ: 117025167(F2RL1)
PALE: 102892595(F2RL1)
PGIG: 120598539(F2RL1)
PVP: 105302170(F2RL1)
RAY: 107501532(F2RL1)
MJV: 108387165(F2RL1)
TOD: 119260284(F2RL1)
SARA: 101539080(F2RL1)
SETR: 126001873(F2RL1)
LAV: 100669271(F2RL1)
TMU: 101357787
ETF: 101651568(F2RL1)
DNM: 101431876(F2RL1)
MDO: 100010197(F2RL1)
GAS: 123231444(F2RL1)
SHR: 100934491(F2RL1)
AFZ: 127558715
PCW: 110216633(F2RL1)
TVP: 118851136(F2RL1)
OAA: 100083214(F2RL1)
GGA: 427213(F2RL1)
PCOC: 116239893(F2RL1)
MGP: 100543031(F2RL1)
CJO: 107305929(F2RL1)
TPAI: 128074671(F2RL1)
LMUT: 125687037(F2RL1)
NMEL: 110389969(F2RL1)
APLA: 101791388(F2RL1)
ACYG: 106042094(F2RL1)
CATA: 118251421
AFUL: 116500374(F2RL1)
TGU: 100226444(F2RL1)
LSR: 110471305(F2RL1)
SCAN: 103819538(F2RL1)
PMOA: 120511990(F2RL1)
OTC: 121341291(F2RL1)
PRUF: 121363655(F2RL1)
GFR: 102045423(F2RL1)
FAB: 101815040(F2RL1)
OMA: 130265301(F2RL1)
PHI: 102110361(F2RL1)
PMAJ: 107198508(F2RL1)
CCAE: 111940827(F2RL1)
CCW: 104698565(F2RL1)
CBRC: 103622038(F2RL1)
ETL: 114057026(F2RL1)
ZAB: 102072132(F2RL1)
ZLE: 135459611(F2RL1)
ACHL: 103808711(F2RL1)
SVG: 106860899(F2RL1)
MMEA: 130572261(F2RL1)
HRT: 120765412(F2RL1)
SATI: 136373496(F2RL1)
FPG: 101917800(F2RL1)
FCH: 102055035(F2RL1)
CCRI: 104157628(F2RL1)
NNT: 104409324(F2RL1)
SHAB: 115600930(F2RL1)
ACUN: 113489901(F2RL1)
TALA: 104362936(F2RL1)
ACHC: 115337344(F2RL1)
HALD: 104323959(F2RL1)
HLE: 104841284(F2RL1)
AGEN: 126036280
GCL: 127027525
CSTI: 104558246(F2RL1)
LDI: 104345518(F2RL1)
MNB: 103779644
DPUB: 104306403
AVIT: 104277053(F2RL1)
BRHI: 104497266(F2RL1)
EGZ: 104124891(F2RL1)
NNI: 104013342(F2RL1)
PCRI: 104032908(F2RL1)
PCAO: 104048231(F2RL1)
PADL: 103919757(F2RL1)
AFOR: 103899789(F2RL1)
FGA: 104082849(F2RL1)
GSTE: 104257747(F2RL1)
CLV: 102096314(F2RL1)
MUI: 104547209(F2RL1)
PGUU: 104470198(F2RL1)
PLET: 104617896(F2RL1)
EHS: 104506857(F2RL1)
CMAC: 104481500(F2RL1)
CUCA: 104056399(F2RL1)
TEO: 104371708(F2RL1)
BREG: 104636159(F2RL1)
OHA: 104336026(F2RL1)
ACAR: 104525577(F2RL1)
CPEA: 104395808(F2RL1)
CVF: 104285798(F2RL1)
RTD: 128903101(F2RL1)
AROW: 112967043(F2RL1)
NPD: 112944054(F2RL1)
TGT: 104565644(F2RL1)
DNE: 112987105(F2RL1)
SCAM: 104152987(F2RL1)
ASN: 102373577(F2RL1)
AMJ: 102559405(F2RL1)
CPOO: 109308015(F2RL1)
GGN: 109297723(F2RL1)
PSS: 102452058(F2RL1)
CMY: 102932670(F2RL1)
CCAY: 125636452(F2RL1)
DCC: 119855986(F2RL1)
CPIC: 101935517(F2RL1)
TST: 117879452(F2RL1)
CABI: 116821305(F2RL1)
MRV: 120408727(F2RL1)
ACS: 100566476(f2rl1)
ASAO: 132767062(F2RL1)
PVT: 110084602(F2RL1)
SUND: 121923902(F2RL1)
PBI: 103057121(F2RL1)
PMUR: 107293559(F2RL1)
CTIG: 120317404(F2RL1)
TSR: 106539007(F2RL1)
PGUT: 117679289(F2RL1)
APRI: 131193237(F2RL1)
PTEX: 113447563(F2RL1)
NSS: 113413955(F2RL1)
VKO: 123031466(F2RL1)
PMUA: 114606618(F2RL1)
PRAF: 128423333(F2RL1)
ZVI: 118076834(F2RL1)
HCG: 128341593(F2RL1)
GJA: 107117429(F2RL1) 107125247
STOW: 125437298(F2RL1)
EMC: 129334638(F2RL1)
XLA: 108707269 496315(f2rl1.L) 496339(f2rl1.S)
XTR: 100490447(f2rl1)
NPR: 108787662(F2RL1)
RTEM: 120929517(F2RL1)
BBUF: 120992430(F2RL1)
BGAR: 122936052(F2RL1)
MUO: 115463063(F2RL1)
GSH: 117353348(F2RL1)
DRE: 100073342(f2rl1.2) 794649(f2rl1.1)
PTET: 122341031(f2rl1.2) 122341114(f2rl1.1)
LROH: 127151995(f2rl1.1) 127152401(f2rl1.2)
OMC: 131529516(f2rl1.1) 131529517(f2rl1.2)
PPRM: 120491529 120491667 120491717(f2rl1.1)
RKG: 130090735 130090739(f2rl1.1) 130090743(f2rl1.2)
MAMB: 125252932(f2rl1.2) 125252934(f2rl1.1)
CERY: 137012867(f2rl1.2) 137012869(f2rl1.1)
TROS: 130570342(f2rl1.1) 130570755(f2rl1.2) 130570756
MANU: 129424298(f2rl1.2) 129424335(f2rl1.1)
IPU: 108278807
IFU: 128622829
SMEO: 124397548
TFD: 113646553
TVC: 132859615
CHAR: 105902423
TFS: 130516913(f2rl1.2)
TBEN: 117476662(f2rl1.1) 117476783 117500137
PGEO: 117456303(f2rl1.2) 117456381(f2rl1.1)
GACU: 117561386(f2rl1.2)
EMAC: 134868232(f2rl1.1) 134868808
ELY: 117270196 117270197(f2rl1.1)
EFO: 125905756(f2rl1.1) 125905757(f2rl1.2)
PLEP: 121959807(f2rl1.1) 121959848 121963601
SLUC: 116062948 116062949 116062989(f2rl1.2)
ECRA: 117959167(f2rl1.2) 117959170(f2rl1.1)
GAT: 120831730(f2rl1.1) 120831741(f2rl1.2)
PPUG: 119226182(f2rl1.2) 119226879(f2rl1.1)
AFB: 129102314 129102315(f2rl1.2)
CLUM: 117740051 117740523(f2rl1.2)
PSWI: 130205273(f2rl1.1) 130205413
SCHU: 122865405 122865792(f2rl1.2)
CUD: 121525558(f2rl1.2) 121525682(f2rl1.1)
OAU: 116315898 116315938(f2rl1.2)
OML: 112162740 112162802(f2rl1.1)
XCO: 114149336(f2rl1) 114149337
XHE: 116724374 116724863(f2rl1)
PPRL: 129374189(f2rl1.2) 129374193
CTUL: 119788272 119788274 119788286(f2rl1.2)
GMU: 124872194 124872220(f2rl1.2)
NFU: 107374833 107374834(f2rl1)
MCEP: 124996385(f2rl1.2) 124996386
SSEN: 122787085(f2rl1.1) 122787097(f2rl1.2)
HHIP: 117772162 117772163(f2rl1.1) 117772165
SMAU: 118300475(f2rl1.2) 118300478(f2rl1.1)
LCF: 108873762 108873770(f2rl1.1)
XGL: 120805999(f2rl1.2) 120806024(f2rl1.1)
HCQ: 109529263(f2rl1)
SBIA: 133491051(f2rl1.2) 133491052
PEE: 133413816 133413817(f2rl1.1)
PTAO: 133465240(f2rl1.2) 133465241
BSPL: 114867201(f2rl1.1) 114867338(f2rl1.2)
SFM: 108925089(f2rl1) 108937986
AANG: 118213426(s100z) 118237196
PSEX: 120532427(f2rl1.2)
CMK: 103186384
RTP: 109917595(f2rl1.2)
CPLA: 122558542(f2rl1.2)
HOC: 132827158(f2rl1.2)
LERI: 129694689
PMEO: 129592612
BGT: 106079890
CRG: 117684942
 » show all
Reference
PMID:8615752
  Authors
Bohm SK, Kong W, Bromme D, Smeekens SP, Anderson DC, Connolly A, Kahn M, Nelken NA, Coughlin SR, Payan DG, Bunnett NW
  Title
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
  Journal
Biochem J 314 ( Pt 3):1009-16 (1996)
DOI:10.1042/bj3141009
  Sequence
[hsa:2150]

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