KEGG   ORTHOLOGY: K04339
Entry
K04339            Tight     KO                                     

Name
stsE
Definition
scyllo-inosamine 4-kinase [EC:2.7.1.65]
Pathway
ko00521  Streptomycin biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    K04339  stsE; scyllo-inosamine 4-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.65  scyllo-inosamine 4-kinase
     K04339  stsE; scyllo-inosamine 4-kinase
Other DBs
RN: R03384
GO: 0050276
Genes
SGR: SGR_5919(stsE)

KEGG   ENZYME: 2.7.1.65
Entry
EC 2.7.1.65                 Enzyme                                 

Name
scyllo-inosamine 4-kinase;
scyllo-inosamine kinase (phosphorylating);
scyllo-inosamine kinase;
ATP:inosamine phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase
Reaction(IUBMB)
ATP + 1-amino-1-deoxy-scyllo-inositol = ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate [RN:R03384]
Reaction(KEGG)
R03384
Substrate
ATP [CPD:C00002];
1-amino-1-deoxy-scyllo-inositol [CPD:C01214]
Product
ADP [CPD:C00008];
1-amino-1-deoxy-scyllo-inositol 4-phosphate [CPD:C01283]
Comment
Also acts on streptamine, 2-deoxystreptamine and 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol.
History
EC 2.7.1.65 created 1972, modified 1976
Pathway
ec00521  Streptomycin biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K04339  scyllo-inosamine 4-kinase
Genes
SGR: SGR_5919(stsE)
Reference
1  [PMID:4376579]
  Authors
Walker JB.
  Title
Enzymatic reactions involved in streptomycin biosynthesis and metabolism.
  Journal
Lloydia 34:363-71 (1971)
Reference
2  [PMID:6076630]
  Authors
Walker JB, Walker MS.
  Title
Enzymatic synthesis of streptidine from scyllo-inosamine.
  Journal
Biochemistry 6:3821-9 (1967)
DOI:10.1021/bi00864a028
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.65
IUBMB Enzyme Nomenclature: 2.7.1.65
ExPASy - ENZYME nomenclature database: 2.7.1.65
BRENDA, the Enzyme Database: 2.7.1.65
CAS: 37278-08-3

KEGG   REACTION: R03384
Entry
R03384                      Reaction                               

Name
ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase
Definition
ATP + 1-Amino-1-deoxy-scyllo-inositol <=> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate
Equation
Reaction class
RC00002  C00002_C00008
RC00078  C01214_C01283
Enzyme
Pathway
rn00521  Streptomycin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K04339  scyllo-inosamine 4-kinase [EC:2.7.1.65]
Other DBs
RHEA: 18608

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