| Entry |
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| Name |
scyllo-inosamine-4-phosphate amidinotransferase;
L-arginine:inosamine-P-amidinotransferase;
inosamine-P amidinotransferase;
L-arginine:inosamine phosphate amidinotransferase;
inosamine-phosphate amidinotransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Amidinotransferases
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| Sysname |
L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase
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| Reaction(IUBMB) |
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate = L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [RN: R03477]
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| Reaction(KEGG) |
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| Substrate |
L-arginine [CPD: C00062];
1-amino-1-deoxy-scyllo-inositol 4-phosphate [CPD: C01283]
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| Product |
L-ornithine [CPD: C00077];
1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [CPD: C01294]
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| Comment |
1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate, streptamine phosphate and 2-deoxystreptamine phosphate can also act as acceptors; canavanine can act as donor.
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| History |
EC 2.1.4.2 created 1976, modified 2001
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K04340 | scyllo-inosamine-4-phosphate amidinotransferase 1 |
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| Genes |
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| Reference |
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| Authors |
Walker MS, Walker JB. |
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| Title |
Enzymic studies on the biosynthesis of streptomycin. Transamidination of inosamine and streptamine derivatives. |
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| Journal |
J Biol Chem 241:1262-70 (1966) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.1.4.2 |
| ExPASy - ENZYME nomenclature database: | 2.1.4.2 |
| BRENDA, the Enzyme Database: | 2.1.4.2 |
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