KEGG   ORTHOLOGY: K04464
Entry
K04464                      KO                                     
Symbol
MAPK7
Name
mitogen-activated protein kinase 7 [EC:2.7.11.24]
Pathway
map04010  MAPK signaling pathway
map04011  MAPK signaling pathway - yeast
map04138  Autophagy - yeast
map04139  Mitophagy - yeast
map04540  Gap junction
map04657  IL-17 signaling pathway
map04722  Neurotrophin signaling pathway
map04912  GnRH signaling pathway
map04921  Oxytocin signaling pathway
map05206  MicroRNAs in cancer
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04011 MAPK signaling pathway - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
 09140 Cellular Processes
  09141 Transport and catabolism
   04138 Autophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
   04139 Mitophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04464  MAPK7; mitogen-activated protein kinase 7
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04921 Oxytocin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K04464  MAPK7; mitogen-activated protein kinase 7
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04464  MAPK7; mitogen-activated protein kinase 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04464  MAPK7; mitogen-activated protein kinase 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04464  MAPK7; mitogen-activated protein kinase 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04464  MAPK7; mitogen-activated protein kinase 7
Other DBs
COG: COG0515
GO: 0004707
Genes
HSA: 5598(MAPK7)
PTR: 454499(MAPK7)
PPS: 100967254(MAPK7)
GGO: 101137450(MAPK7)
PON: 100451029(MAPK7)
NLE: 100598787(MAPK7)
HMH: 116483083(MAPK7)
MCC: 702837(MAPK7)
MCF: 102133212(MAPK7)
MTHB: 126939027
MNI: 105493340(MAPK7)
CSAB: 103242509(MAPK7)
CATY: 105593716(MAPK7)
PANU: 100999653(MAPK7)
TGE: 112609132(MAPK7)
MLEU: 105552550(MAPK7)
RRO: 104660707(MAPK7)
RBB: 108516767(MAPK7)
TFN: 117067583(MAPK7)
PTEH: 111528146(MAPK7)
CANG: 105521000(MAPK7)
CJC: 100400023(MAPK7)
SBQ: 101050659(MAPK7)
CIMI: 108293479(MAPK7)
CSYR: 103273099(MAPK7)
MMUR: 105862003(MAPK7)
LCAT: 123621221(MAPK7)
PCOQ: 105816097(MAPK7)
OGA: 100962878(MAPK7)
MMU: 23939(Mapk7)
MCAL: 110305070(Mapk7)
MPAH: 110331679(Mapk7)
RNO: 114509(Mapk7)
MCOC: 116077931(Mapk7)
ANU: 117710519(Mapk7)
MUN: 110549800(Mapk7)
CGE: 100758520(Mapk7)
MAUA: 101835661(Mapk7)
PROB: 127219167(Mapk7)
PLEU: 114683277(Mapk7)
MORG: 121456806(Mapk7)
MFOT: 126514647
AAMP: 119812382(Mapk7)
NGI: 103728439(Mapk7)
HGL: 101726391(Mapk7)
CPOC: 100728396(Mapk7)
CCAN: 109699716(Mapk7)
DORD: 105985870(Mapk7)
DSP: 122103406(Mapk7)
PLOP: 125366140(Mapk7)
NCAR: 124980909
MMMA: 107157135(Mapk7)
OCU: 100338535
OPI: 101525007(MAPK7)
TUP: 102475335(MAPK7)
GVR: 103598189(MAPK7)
CFA: 489532(MAPK7)
CLUD: 112647275(MAPK7)
VVP: 112924943(MAPK7)
VLG: 121499670(MAPK7)
NPO: 129497623(MAPK7)
AML: 100470193(MAPK7)
UMR: 103658546(MAPK7)
UAH: 113271274(MAPK7)
UAR: 123779755(MAPK7)
ELK: 111139244
LLV: 125088025
MPUF: 101676890(MAPK7)
MNP: 132004382(MAPK7)
MLK: 131816173(MAPK7)
NVS: 122906879(MAPK7)
ORO: 101365927(MAPK7)
EJU: 114198222(MAPK7)
ZCA: 113908317(MAPK7)
MLX: 118000125(MAPK7)
NSU: 110584596(MAPK7)
LWW: 102729115(MAPK7)
FCA: 101097357(MAPK7)
PYU: 121015826(MAPK7)
PCOO: 112857063(MAPK7)
PBG: 122485025(MAPK7)
PVIV: 125151410(MAPK7)
LRUF: 124519580
PTG: 102964803(MAPK7)
PPAD: 109245794(MAPK7)
PUC: 125917734
AJU: 106981402
HHV: 120228757(MAPK7)
BTA: 537703(MAPK7)
BOM: 102278560(MAPK7)
BIU: 109574161(MAPK7)
BBUB: 102401035(MAPK7)
BBIS: 104990859(MAPK7)
CHX: 102180534(MAPK7)
OAS: 101110073(MAPK7)
BTAX: 128064484(MAPK7)
ODA: 120867405(MAPK7)
CCAD: 122444207(MAPK7)
MBEZ: 129544202(MAPK7)
SSC: 102164433(MAPK7)
CFR: 106728541(MAPK7)
CBAI: 105061624(MAPK7)
CDK: 105100603(MAPK7)
VPC: 102541255(MAPK7)
BACU: 102999884(MAPK7)
BMUS: 118886442(MAPK7)
LVE: 103080813(MAPK7)
OOR: 101284808(MAPK7)
DLE: 111167739(MAPK7)
PCAD: 102983466(MAPK7)
PSIU: 116745964(MAPK7)
NASI: 112405337(MAPK7)
ECB: 100073174(MAPK7)
EPZ: 103565868(MAPK7)
EAI: 106837912(MAPK7)
MYB: 102245831(MAPK7)
MYD: 102769984(MAPK7)
MMYO: 118649370(MAPK7)
MLF: 102437971(MAPK7)
PKL: 118726794(MAPK7)
EFUS: 103299365(MAPK7)
MNA: 107524519(MAPK7)
DRO: 112308530(MAPK7)
SHON: 119002719(MAPK7)
AJM: 119062269(MAPK7)
PDIC: 114515026(MAPK7)
PHAS: 123809287(MAPK7)
MMF: 118641262(MAPK7)
PPAM: 129068690(MAPK7)
HAI: 109377280(MAPK7)
RFQ: 117013633(MAPK7)
PALE: 102897014(MAPK7)
PGIG: 120589838(MAPK7)
PVP: 105291313(MAPK7)
RAY: 107511070(MAPK7)
MJV: 108409115(MAPK7)
TOD: 119231187(MAPK7)
SARA: 101541530(MAPK7)
LAV: 100671889(MAPK7)
TMU: 101346669
ETF: 101654790(MAPK7)
DNM: 101419178(MAPK7)
MDO: 100016316(MAPK7)
GAS: 123235108(MAPK7)
SHR: 100917749(MAPK7)
AFZ: 127561302
PCW: 110220473(MAPK7)
OAA: 100088657(MAPK7)
GGA: 100858386
PCOC: 116240152
MGP: 104916721(MAPK7)
CJO: 107307520(MAPK7)
NMEL: 110391499(MAPK7)
APLA: 119715311(MAPK7)
ACYG: 106029394(MAPK7)
CATA: 118261621(MAPK7)
PMOA: 120512580
PRUF: 121349796
FAB: 101806540
PHI: 102111242(MAPK7)
PMAJ: 107199450
SVG: 106863770(MAPK7)
MMEA: 130587779(MAPK7)
FPG: 101912679
NNI: 104014494(MAPK7)
AFOR: 103903861(MAPK7)
HLE: 104836865(MAPK7)
CCRI: 104159542(MAPK7)
ACAR: 104529765(MAPK7)
RTD: 128903528(MAPK7)
AROW: 112966431(MAPK7)
ASN: 102386241(MAPK7)
AMJ: 102577139(MAPK7)
PSS: 102463278(MAPK7)
CMY: 102938366(MAPK7)
CCAY: 125639095(MAPK7)
DCC: 119856779(MAPK7)
CPIC: 101932787(MAPK7)
TST: 117876618(MAPK7)
CABI: 116816166(MAPK7)
MRV: 120403296(MAPK7)
ACS: 100553854(mapk7)
ASAO: 132777726(MAPK7)
PVT: 110086378(MAPK7)
SUND: 121935390(MAPK7)
PBI: 103052089(MAPK7)
PMUR: 107290240(MAPK7)
CTIG: 120302324(MAPK7)
TSR: 106557409(MAPK7)
PGUT: 117666845(MAPK7)
APRI: 131197298(MAPK7)
PTEX: 113449965(MAPK7)
NSS: 113422517(MAPK7)
VKO: 123019595(MAPK7)
PMUA: 114582827(MAPK7)
PRAF: 128400639(MAPK7)
ZVI: 118094142(MAPK7)
HCG: 128329763(MAPK7)
GJA: 107122186(MAPK7)
STOW: 125445196(MAPK7)
EMC: 129338213(MAPK7)
XLA: 446599(mapk7.L)
XTR: 779785(mapk7)
NPR: 108800678(MAPK7)
RTEM: 120942977(MAPK7)
BBUF: 121007785(MAPK7)
BGAR: 122944495(MAPK7)
MUO: 115474613(MAPK7)
GSH: 117361200(MAPK7)
DRE: 541323(mapk7)
SRX: 107719547
SANH: 107654010
SGH: 107557341
LROH: 127173906(mapk7)
OMC: 131551075(mapk7)
PPRM: 120468974(mapk7)
RKG: 130080592(mapk7)
MAMB: 125255330(mapk7)
CIDE: 127523710
TROS: 130569627(mapk7)
TDW: 130438641(mapk7)
MANU: 129420705(mapk7)
IPU: 108273635
IFU: 128616920(mapk7)
PHYP: 113527556(mapk7)
SMEO: 124388748(mapk7)
TFD: 113653549(mapk7)
TVC: 132841554(mapk7)
AMEX: 103030026(mapk7)
CMAO: 118809727(mapk7)
EEE: 113591949(mapk7)
CHAR: 105892715(mapk7)
TRU: 101079574(mapk7)
TFS: 130522435(mapk7)
LCO: 104935550(mapk7)
NCC: 104967446(mapk7)
TBEN: 117473340(mapk7)
CGOB: 115024627
PGEO: 117464908(mapk7)
GACU: 117544887(mapk7)
EMAC: 134871212(mapk7)
ELY: 117246705(mapk7)
EFO: 125880839(mapk7)
PLEP: 121958387(mapk7)
SLUC: 116061553(mapk7)
ECRA: 117937273(mapk7)
ESP: 116671107(mapk7)
PFLV: 114548107(mapk7)
GAT: 120819066(mapk7)
PPUG: 119212593(mapk7)
AFB: 129091178(mapk7)
CLUM: 117748510(mapk7)
PSWI: 130203796(mapk7)
MSAM: 119915935(mapk7)
SCHU: 122867173(mapk7)
CUD: 121528202(mapk7)
ALAT: 119009758(mapk7)
MZE: 101467194(mapk7)
ONL: 102082809
OAU: 116321897(mapk7)
OLA: 101157651
OML: 112154202(mapk7)
CSAI: 133419507(mapk7)
XMA: 102229633(mapk7)
XCO: 114134421(mapk7)
XHE: 116727133(mapk7)
PRET: 103481413(mapk7)
PFOR: 103156837(mapk7)
PLAI: 106939028(mapk7)
PMEI: 106908659(mapk7)
GAF: 122823578(mapk7)
PPRL: 129377659(mapk7)
CVG: 107097215(mapk7)
CTUL: 119796752(mapk7)
GMU: 124874783(mapk7)
NFU: 107387979(mapk7)
KMR: 108237269(mapk7)
ALIM: 106521362(mapk7)
NWH: 119423971(mapk7)
AOCE: 111581585
MCEP: 125022354(mapk7)
CSEM: 103382039(mapk7)
POV: 109641502(mapk7)
SSEN: 122762753(mapk7)
HHIP: 117752778(mapk7)
HSP: 118101055(mapk7)
SMAU: 118287271(mapk7)
LCF: 108884456
SDU: 111220321(mapk7)
SLAL: 111658704
XGL: 120794867(mapk7)
HCQ: 109523949(mapk7)
SSCV: 125990903
SBIA: 133496021(mapk7)
PEE: 133417997(mapk7)
PTAO: 133469690(mapk7)
BPEC: 110159641
MALB: 109963593
BSPL: 114845515(mapk7)
SJO: 128381311(mapk7)
SASA: 106586755(mapk7)
STRU: 115161285(mapk7)
OTW: 112242455(mapk7)
OMY: 110520562(mapk7)
OGO: 124044212(mapk7)
ONE: 115113193(mapk7)
OKI: 109870513
OKE: 118366739(mapk7)
SALP: 111980038
SNH: 120058506(mapk7)
CCLU: 121536566
ELS: 105007802(mapk7)
SFM: 108941647(mapk7)
PKI: 111836823
AANG: 118220211(mapk7)
LOC: 102696491(mapk7)
PSPA: 121306863(mapk7)
PSEX: 120519620(mapk7)
LCM: 102358623(MAPK7)
RTP: 109925206(mapk7)
HOC: 132808884(mapk7)
LERI: 129694871
PMRN: 116937143
BFO: 118426721
BBEL: 109464810
CIN: 778597(erk5)
SPU: 574672
LPIC: 129254733
APLC: 110988303
SKO: 100376580
CEL: CELE_C04G6.1(mpk-2)
CBR: CBG_02327(Cbr-mpk-2)
PVUL: 126823887
PCAN: 112561284
BGT: 106056165
GAE: 121368486
HRF: 124147732
HRJ: 124286958
CRG: 105318778
CVN: 111136514
CANU: 128189613
OED: 125647530
MYI: 110446046
PMAX: 117333409
MCAF: 127711745
MMER: 123533674
OBI: 106880255
OSN: 115224348
LAK: 106179980
NVE: 5512299
EPA: 110250865
ATEN: 116293978
ADF: 107339979
AMIL: 114960587
PDAM: 113676680
SPIS: 111331308
XEN: 124434910
HMG: 100213301
HSY: 130623566
AQU: 100635536
ATH: AT2G46070(MPK12) AT4G11330(MPK5)
CRB: 17883824
THJ: 104817310
OSA: 4349225
DOSA: Os10t0533600-01(Os10g0533600)
OBR: 102701584
OGL: 127752871
TUA: 125510579
LPER: 127307179
SBI: 8062876
ZMA: 542144
SITA: 101786841
SVS: 117837957
PHAI: 112875328
SCE: YHR030C(SLT2)
ERC: Ecym_7361
KMX: KLMA_70325(SLT2)
NCS: NCAS_0A06680(NCAS0A06680)
NDI: NDAI_0D01620(NDAI0D01620)
TPF: TPHA_0B02440(TPHA0B02440)
TBL: TBLA_0A10420(TBLA0A10420)
TDL: TDEL_0E03520(TDEL0E03520)
KAF: KAFR_0E01810(KAFR0E01810)
KNG: KNAG_0M01450(KNAG0M01450)
CAL: CAALFM_CR00120CA(MKC1)
CDU: CD36_25140(MKC1)
SLB: AWJ20_17(SLT2)
BNN: FOA43_002713(SLT2)
BBRX: BRETT_001612(SLT2)
MGR: MGG_04943
FPU: FPSE_12362(MGV1)
TRE: TRIREDRAFT_82351(tmk2)
MAW: MAC_08024
MAJ: MAA_03181
BFU: BCIN_09g02390(bmp3)
MBE: MBM_07936
ALUC: AKAW2_21000S(MPK1)
ACHE: ACHE_10418S(MPK1)
APUU: APUU_41042A(MPK1)
ZTR: MYCGRDRAFT_102121(MgSlt2)
SPO: SPBC119.08(pmk1)
SOM: SOMG_02281(pmk1)
CNE: CNI00410
CNB: CNBH0400
CDEU: CNBG_2556
TASA: A1Q1_00040
CCAC: CcaHIS019_0510880(tmk2)
 » show all
Reference
PMID:7646528
  Authors
Lee JD, Ulevitch RJ, Han J
  Title
Primary structure of BMK1: a new mammalian map kinase.
  Journal
Biochem Biophys Res Commun 213:715-24 (1995)
DOI:10.1006/bbrc.1995.2189
  Sequence
[hsa:5598]
Reference
  Authors
Hayashi M, Tapping RI, Chao TH, Lo JF, King CC, Yang Y, Lee JD
  Title
BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.
  Journal
J Biol Chem 276:8631-4 (2001)
DOI:10.1074/jbc.C000838200
  Sequence
[hsa:5598]
Reference
PMID:9111331
  Authors
Watanabe Y, Takaesu G, Hagiwara M, Irie K, Matsumoto K
  Title
Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.
  Journal
Mol Cell Biol 17:2615-23 (1997)
DOI:10.1128/MCB.17.5.2615
  Sequence
[sce:YHR030C]

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