KEGG   ORTHOLOGY: K04468
Entry
K04468                      KO                                     
Symbol
NLK
Name
nemo like kinase [EC:2.7.11.24]
Pathway
map04010  MAPK signaling pathway
map04068  FoxO signaling pathway
map04310  Wnt signaling pathway
map04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04468  NLK; nemo like kinase
   04310 Wnt signaling pathway
    K04468  NLK; nemo like kinase
   04068 FoxO signaling pathway
    K04468  NLK; nemo like kinase
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04468  NLK; nemo like kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04468  NLK; nemo like kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04468  NLK; nemo like kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04468  NLK; nemo like kinase
Genes
HSA: 51701(NLK)
PTR: 739132(NLK)
PPS: 100979222(NLK) 100980541
GGO: 101138810(NLK)
PON: 100437341(NLK)
NLE: 100593981(NLK)
HMH: 116474630(NLK)
MCC: 677693(NLK)
MCF: 101865361(NLK)
MTHB: 126938723
MNI: 105476015(NLK)
CSAB: 103242604(NLK)
CATY: 105591505(NLK)
PANU: 101006391(NLK)
TGE: 112609928(NLK)
MLEU: 105552046(NLK)
RRO: 104669360(NLK)
RBB: 108539940(NLK)
TFN: 117067607(NLK)
PTEH: 111520786(NLK)
CANG: 105510815(NLK)
CJC: 100414864(NLK)
SBQ: 101042695(NLK)
CIMI: 108296907(NLK)
CSYR: 103269139(NLK)
MMUR: 105857929(NLK)
LCAT: 123620293(NLK)
PCOQ: 105813553(NLK)
OGA: 100956941(NLK)
MMU: 18099(Nlk)
MCAL: 110305742(Nlk)
MPAH: 110331754(Nlk)
RNO: 497961(Nlk)
MCOC: 116077179(Nlk)
ANU: 117710510(Nlk)
MUN: 110550145(Nlk)
CGE: 100768473(Nlk)
MAUA: 101824626(Nlk)
PROB: 127218831(Nlk)
PLEU: 114691513(Nlk)
MORG: 121456490(Nlk)
MFOT: 126492313
AAMP: 119812516(Nlk)
NGI: 103724495(Nlk)
HGL: 101701893(Nlk)
CPOC: 100729077(Nlk)
CCAN: 109698362(Nlk)
DORD: 105985659(Nlk)
DSP: 122117356(Nlk)
PLOP: 125365478(Nlk)
NCAR: 124980470
MMMA: 107155275(Nlk)
OCU: 100348930
OPI: 101535874(NLK)
TUP: 102468920(NLK)
GVR: 103595980(NLK)
CFA: 491160(NLK)
CLUD: 112677681(NLK)
VVP: 112933031(NLK)
VLG: 121473034(NLK)
NPO: 129515376(NLK)
AML: 100469296(NLK)
UMR: 103667237(NLK)
UAH: 113269022(NLK)
UAR: 123777097(NLK)
ELK: 111151399
LLV: 125087256
MPUF: 101693629(NLK)
MNP: 132003187(NLK)
MLK: 131817095(NLK)
NVS: 122906425(NLK)
ORO: 101382029(NLK)
EJU: 114213945(NLK)
ZCA: 113939743(NLK)
MLX: 118025301(NLK)
NSU: 110592921(NLK)
LWW: 102725586(NLK)
FCA: 101080751(NLK)
PYU: 121017182(NLK)
PCOO: 112853429(NLK)
PBG: 122485181(NLK)
LRUF: 124513036
PTG: 102950636(NLK)
PPAD: 109251873(NLK)
PUC: 125927481
AJU: 106983267
HHV: 120246055(NLK)
BTA: 507204(NLK)
BOM: 102274050(NLK)
BIU: 109574074(NLK)
BBUB: 102411302(NLK)
BBIS: 105003967(NLK)
CHX: 102190163(NLK)
OAS: 101103076(NLK) 114118747
BTAX: 128065136(NLK)
ODA: 120866310(NLK)
CCAD: 122448607(NLK)
MBEZ: 129540576(NLK)
SSC: 100511657(NLK)
CFR: 102519162(NLK)
CBAI: 105071635(NLK)
CDK: 105088250(NLK)
VPC: 102533857(NLK)
BACU: 103002389(NLK)
LVE: 103075265(NLK)
OOR: 101279962(NLK)
DLE: 111185994(NLK)
PCAD: 102989137(NLK)
PSIU: 116745906(NLK)
NASI: 112394478(NLK)
ECB: 100058876(NLK)
EPZ: 103555963(NLK)
EAI: 106844594(NLK)
MYB: 102246580(NLK)
MYD: 102760175(NLK)
MMYO: 118671812(NLK)
MLF: 102424419(NLK)
MNA: 107528767(NLK)
PKL: 118702529(NLK)
EFUS: 103291699(NLK)
HAI: 109385136(NLK)
DRO: 112308929(NLK)
SHON: 119003760(NLK)
AJM: 119061977(NLK)
PDIC: 114502295(NLK)
PHAS: 123817421(NLK)
MMF: 118633768(NLK)
RFQ: 117013722(NLK)
PPAM: 129070287(NLK)
PALE: 102890853(NLK)
PGIG: 120620948(NLK)
PVP: 105291932(NLK)
RAY: 107497403(NLK)
MJV: 108397019(NLK)
TOD: 119232042(NLK)
SARA: 101555718(NLK)
LAV: 100668196(NLK)
TMU: 101340490
ETF: 101659623(NLK)
DNM: 101420847(NLK)
MDO: 100019356(NLK)
GAS: 123244374(NLK)
SHR: 100928564(NLK)
AFZ: 127558940
PCW: 110192184(NLK)
OAA: 100075452(NLK)
GGA: 417669(NLK)
PCOC: 116227906(NLK)
MGP: 100546825(NLK)
CJO: 107322736(NLK)
TPAI: 128083625(NLK)
LMUT: 125702894(NLK)
NMEL: 110407803(NLK)
APLA: 101804891(NLK)
ACYG: 106043757(NLK)
CATA: 118255046(NLK)
AFUL: 116497142(NLK)
TGU: 100217568(NLK)
LSR: 110471960(NLK)
SCAN: 103820200(NLK)
PMOA: 120507770(NLK)
OTC: 121347054(NLK)
PRUF: 121361823(NLK)
GFR: 102033058(NLK)
FAB: 101817298(NLK)
OMA: 130260958(NLK)
PHI: 102108455(NLK)
PMAJ: 107212813(NLK)
CCAE: 111937883(NLK)
CCW: 104691151(NLK)
CBRC: 103613308(NLK)
ETL: 114057508(NLK)
ZAB: 102070076(NLK)
ACHL: 103807978(NLK)
SVG: 106856064(NLK)
MMEA: 130581372(NLK)
HRT: 120761419(NLK)
FPG: 101915315(NLK)
FCH: 102053931(NLK)
CLV: 102086843(NLK)
EGZ: 104121926(NLK)
NNI: 104016227(NLK)
PLET: 104619315(NLK)
EHS: 104510786(NLK)
PCAO: 104052176(NLK)
ACUN: 113487042(NLK)
TALA: 104360296(NLK)
PADL: 103912520(NLK)
AFOR: 103898065(NLK)
ACHC: 115346927(NLK)
HALD: 104321177(NLK)
HLE: 104835706(NLK)
AGEN: 126039159
GCL: 127024618
CCRI: 104166955(NLK)
CSTI: 104558283(NLK)
CMAC: 104482234(NLK)
MUI: 104539228(NLK)
BREG: 104640909(NLK)
FGA: 104079918(NLK)
GSTE: 104257568(NLK)
LDI: 104347575(NLK)
MNB: 103778842(NLK)
OHA: 104328049(NLK)
NNT: 104410776(NLK)
SHAB: 115602034(NLK)
DPUB: 104302639(NLK)
PGUU: 104458988(NLK)
ACAR: 104520900(NLK)
CPEA: 104396205(NLK)
AVIT: 104270954(NLK)
CVF: 104283290(NLK)
RTD: 128912570(NLK)
CUCA: 104064986(NLK)
TEO: 104380265(NLK)
BRHI: 104491326(NLK)
AAM: 106498756(NLK)
AROW: 112968208(NLK)
NPD: 112954606(NLK)
TGT: 104577661(NLK)
DNE: 112987051(NLK)
SCAM: 104154155(NLK)
ASN: 102376659(NLK)
AMJ: 102575019(NLK)
CPOO: 109317109(NLK)
GGN: 109293226(NLK)
PSS: 102445212(NLK)
CMY: 102946225(NLK) 119566508
DCC: 119844563(NLK)
CPIC: 101946382 101950703(NLK)
TST: 117867459(NLK)
CABI: 116824206(NLK)
MRV: 120387128(NLK) 120404133
ACS: 100560802(nlk) 100567618
ASAO: 132763478(NLK) 132777807
PVT: 110081806 110088439(NLK)
SUND: 121916817(NLK) 121932732
PBI: 103059532(NLK) 103067037
CTIG: 120302219 120307143(NLK)
TSR: 106543078(NLK) 106545367
PGUT: 117666779 117667439(NLK)
APRI: 131188741(NLK) 131197008
PTEX: 113442555(NLK) 113443577
NSS: 113421730 113422014(NLK)
VKO: 123023451(NLK) 123032152
PMUA: 114581516 114585984(NLK)
PRAF: 128400881 128402298(NLK)
ZVI: 118095230 118096717(NLK)
HCG: 128330614 128336053(NLK)
GJA: 107117625 107119464(NLK)
STOW: 125444704 125445606(NLK)
EMC: 129340639 129344533(NLK)
XLA: 108703801(nlk.2.L) 108709347(nlk.S) 398295(nlk.2.S) 414522(nlk.L)
XTR: 100144638(nlk) 100144684(nlk.2)
NPR: 108789155 108801690(NLK)
RTEM: 120927629(NLK) 120943047
BBUF: 120994729(NLK) 121009017
BGAR: 122930439(NLK) 122944596
MUO: 115474059 115482462(NLK)
GSH: 117348936(NLK) 117361547
DRE: 405892(nlk1) 563460(nlk2)
PTET: 122337270(nlk1) 122358381 122358437(nlk2)
LROH: 127162656(nlk1) 127176734(nlk2)
OMC: 131536236(nlk1) 131554074(nlk2)
PPRM: 120473200(nlk2) 120489136(nlk1)
RKG: 130075220(nlk1) 130104575(nlk2)
MAMB: 125249494(nlk2) 125278531(nlk1)
TROS: 130562019(nlk1) 130564504(nlk2)
TDW: 130426708(nlk1) 130428714(nlk2)
MANU: 129436330(nlk1) 129438175(nlk2)
IPU: 108260705(nlk1) 108277876(nlk2)
IFU: 128601138(nlk1) 128621643(nlk2)
PHYP: 113528537 113539186(nlk)
SMEO: 124394557(nlk2) 124396719(nlk1)
TFD: 113639496(nlk1) 113645104(nlk2)
TVC: 132857770(nlk2) 132861090(nlk1)
AMEX: 103027970 103037551(nlk)
CMAO: 118804040(nlk2) 118820972(nlk1)
CHAR: 105902814(nlk2) 105911998(nlk1)
TRU: 101063351 445934(nlk)
TFS: 130514787(nlk1) 130534906(nlk2)
LCO: 104935892 104938270(nlk)
NCC: 104963083(nlk)
TBEN: 117471063(nlk2) 117492273(nlk1)
CGOB: 115017440(nlk)
PGEO: 117450917(nlk1) 117456835(nlk2)
GACU: 117539816(nlk1) 117555593(nlk2)
ELY: 117259681(nlk2) 117268755(nlk1)
EFO: 125879604(nlk1) 125889086(nlk2)
PLEP: 121942860(nlk2) 121956362(nlk1)
SLUC: 116059058(nlk2) 116060875(nlk1)
ECRA: 117941829(nlk2)
ESP: 116674205(nlk) 116702998
GAT: 120820646(nlk2) 120827906(nlk1)
PPUG: 119216337(nlk2) 119220941(nlk1)
AFB: 129091545 129098953(nlk1)
CLUM: 117734626(nlk1) 117741179(nlk2)
MSAM: 119883124(nlk2) 119895293(nlk1)
SCHU: 122869035(nlk1) 122878823(nlk2)
CUD: 121503406(nlk1) 121519700(nlk2)
ALAT: 119005705(nlk2) 119013554(nlk1)
MZE: 101464874(nlk) 101486522
OAU: 116318621(nlk1) 116323924(nlk2)
OLA: 101162387(nlk) 101168711
OML: 112139979(nlk1) 112151065(nlk2)
XMA: 102231789(nlk) 102233188
XCO: 114159563 114161830(nlk)
PRET: 103469510 103474306(nlk)
PFOR: 103132031 103152788(nlk)
PLAI: 106961670 106963182(nlk)
PMEI: 106911455 106929918(nlk)
GAF: 122821642(nlk1) 122832541(nlk2)
CVG: 107097119 107102441(nlk)
CTUL: 119789974(nlk1) 119795154(nlk2)
KMR: 108248064(nlk2)
NWH: 119421260(nlk1)
AOCE: 111565872(nlk) 111585672
MCEP: 124998283(nlk1) 125013703(nlk2)
CSEM: 103377708(nlk) 103393459
SSEN: 122773774(nlk2) 122785400(nlk1)
HHIP: 117766000(nlk1) 117773159
HSP: 118123470(nlk1)
LCF: 108877931(nlk1) 108899896(nlk2)
SDU: 111235138(nlk) 111238858
SLAL: 111653123 111662558(nlk)
XGL: 120792128(nlk2) 120805465(nlk1)
HCQ: 109510916(nlk) 109513808
SBIA: 133504890(nlk2) 133514065(nlk1)
PEE: 133404857(nlk2) 133415295(nlk1)
PTAO: 133466032(nlk1) 133481781(nlk2)
BPEC: 110156284(nlk) 110170333
SJO: 128360821(nlk2) 128378615(nlk1)
ELS: 105008258 105014125(nlk)
SFM: 108932104(nlk) 108941617
PKI: 111833736 111856400(nlk)
AANG: 118209387(nlk2) 118216411(nlk1) 118236124
LOC: 102693051(nlk)
PSPA: 121306751(nlk1) 121308734(nlk2) 121317053
PSEX: 120531342(nlk2) 120536485(nlk1)
LCM: 102352356(NLK) 102353948
CMK: 103183358(nlk2)
RTP: 109933967(nlk)
CPLA: 122563950(nlk2)
HOC: 132830414(nlk2)
LERI: 129710539(nlk2)
PMRN: 116950134(NLK)
LRJ: 133348958(NLK)
BFO: 118425717
BBEL: 109464569
CIN: 778685(nemo-like)
SCLV: 120345775
SPU: 574783
LPIC: 129253612
APLC: 110980669
AJC: 117116368
SKO: 100313664
DME: Dmel_CG7892(nmo)
DER: 6544158
DSI: Dsimw501_GD14046(Dsim_GD14046)
DSR: 110189098
DPE: 6599854
DMN: 108152329
DGR: 6557597
DAZ: 108612290
DNV: 108650903
CCAT: 101451987
BOD: 106619241
BDR: 105223273
TDA: 119668549
MDE: 101898556
SCAC: 106083982
LCQ: 111688532
GFS: 119645168
ECOE: 129946287
HIS: 119647496
AGA: 1276565
ACOZ: 120961685
AARA: 120900015
AMER: 121591738
AFUN: 125768535
AMOU: 128305905
AALI: 118467350
AAG: 5576036
CNS: 116347129
BCOO: 119080715
AME: 410956
ACER: 107997257
ALAB: 122712691
ADR: 102673009
BIM: 100748253
BBIF: 117206165
BVK: 117235503
BVAN: 117153884
BTER: 100651912
BAFF: 126915993
BPYO: 122566258
BPAS: 132905578
FVI: 122535816
CCAL: 108625280
OBB: 114879137
MGEN: 117218084
NMEA: 116432161
CGIG: 122398494
SOC: 105201288
MPHA: 105835168
AEC: 105144345
ACEP: 105619197
PBAR: 105433421
VEM: 105570659
HST: 105191859
DQU: 106747450
CFO: 105248529
FEX: 115238610
LHU: 105673049
PGC: 109857464
OBO: 105283744
PCF: 106786268
PFUC: 122525645
VPS: 122633414
VCRB: 124429303
NVI: 100121458
CSOL: 105366953
TPRE: 106648586
LHT: 122507607
LBD: 127287368
MDL: 103579781
CGLO: 123265636
FAS: 105269067
DAM: 107039794
AGIF: 122857468
CINS: 118069101
VCAN: 122414409
CCIN: 107270001
DSM: 124410256
NPT: 124218649
NFB: 124182073
NLO: 107223234
NVG: 124304402
TCA: 659674
SOY: 115879224
AGRG: 126742232
ATD: 109593930
CSET: 123313162
LDC: 111504517
NVL: 108557383
APLN: 108739531
PPYR: 116177299
OTU: 111426155
BMOR: 101737550
BMAN: 114248886
MSEX: 115443115
BANY: 112043565
MJU: 123881092
NIQ: 126770195
VCD: 124533324
MCIX: 123653413
PMAC: 106720757
PPOT: 106109108
PXU: 106127130
PRAP: 110996863
PBX: 123717552
PNAP: 125054327
ZCE: 119835282
CCRC: 123690869
LSIN: 126974866
HAW: 110369677
HZE: 124630948
TNL: 113491771
SLIU: 111351547
OFU: 114351065
PXY: 105383690
PGW: 126367542
CCRN: 123294772
API: 100162414
DNX: 107168487
AGS: 114125662
RMD: 113554977
ACOO: 126839381
DVT: 126903000
BTAB: 109043023
CLEC: 106664882
HVI: 124367983
FOC: 113215961
TPAL: 117650908
ZNE: 110840818
CSEC: 111875250
SGRE: 126326117
IEL: 124159417
FCD: 110850640
DMK: 116932834
DPZ: 124350191
PVM: 113821042
PJA: 122264420
PCHN: 125029021
PMOO: 119574194
HAME: 121862881
PCLA: 123748457
CQD: 128693579
PTRU: 123517006
ESN: 127001374
HAZT: 108677038
EAF: 111706738
LSM: 121116000
TCF: 131879628
ISC: 8028864
DSV: 119434606
RSAN: 119390241
RMP: 119172958
VDE: 111253766
VJA: 111271316
TUT: 107370188
DPTE: 113791503
DFR: 124496830
CSCU: 111630388
CEL: CELE_W06F12.1(lit-1)
CBR: CBG_18286(Cbr-lit-1)
BMY: BM_BM6215(Bma-lit-1)
TSP: Tsp_01235
PVUL: 126823238
PCAN: 112561995
BGT: 106065260
GAE: 121367375
HRF: 124110426
HRJ: 124282224
CRG: 105343157
CANU: 128190364
OED: 125677980
MYI: 110464040
PMAX: 117333120
MCAF: 127712271
MMER: 128547380
RPHI: 132721067
DPOL: 127870046
OBI: 106883051
OSN: 115224838
LAK: 106170213
EGL: EGR_00726
NVE: 5501321
EPA: 110236462
ATEN: 116287864
ADF: 107341334
AMIL: 114957463
PDAM: 113685997
SPIS: 111336545
DGT: 114523705
XEN: 124435549
HMG: 100197403
HSY: 130624368
AQU: 100637545
SPAR: SPRG_03095
 » show all
Reference
PMID:9448268
  Authors
Brott BK, Pinsky BA, Erikson RL
  Title
Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus.
  Journal
Proc Natl Acad Sci U S A 95:963-8 (1998)
DOI:10.1073/pnas.95.3.963
  Sequence
[mmu:18099]
Reference
  Authors
Ishitani T, Ishitani S
  Title
Nemo-like kinase, a multifaceted cell signaling regulator.
  Journal
Cell Signal 25:190-7 (2013)
DOI:10.1016/j.cellsig.2012.09.017

DBGET integrated database retrieval system