KEGG   ORTHOLOGY: K04534
Entry
K04534                      KO                                     

Symbol
GNAO, G-ALPHA-O
Name
guanine nucleotide-binding protein G(o) subunit alpha
Pathway
map04015  Rap1 signaling pathway
map04361  Axon regeneration
map04713  Circadian entrainment
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04727  GABAergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map05032  Morphine addiction
map05034  Alcoholism
map05142  Chagas disease
map05145  Toxoplasmosis
map05163  Human cytomegalovirus infection
map05170  Human immunodeficiency virus 1 infection
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04921 Oxytocin signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04926 Relaxin signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04916 Melanogenesis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  09156 Nervous system
   04724 Glutamatergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04727 GABAergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04725 Cholinergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04728 Dopaminergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04726 Serotonergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04730 Long-term depression
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04723 Retrograde endocannabinoid signaling
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  09158 Development and regeneration
   04361 Axon regeneration
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05163 Human cytomegalovirus infection
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05142 Chagas disease
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  09165 Substance dependence
   05032 Morphine addiction
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05034 Alcoholism
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04031 GTP-binding proteins
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
Genes
HSA: 2775(GNAO1)
PTR: 450173(GNAO1)
PPS: 100991540(GNAO1)
GGO: 101150695(GNAO1)
PON: 100454626(GNAO1)
NLE: 100599912(GNAO1)
MCC: 574394(GNAO1)
MCF: 102131761(GNAO1)
CSAB: 103233012(GNAO1)
CATY: 105588486(GNAO1)
PANU: 101018328(GNAO1)
RRO: 104664017(GNAO1)
TFN: 117087809(GNAO1)
PTEH: 111541259(GNAO1)
CJC: 100389396(GNAO1)
SBQ: 101049046(GNAO1)
MMUR: 105866545(GNAO1)
MMU: 14681(Gnao1)
MCAL: 110299754(Gnao1)
MPAH: 110337832(Gnao1)
RNO: 50664(Gnao1)
MCOC: 116069889(Gnao1)
CGE: 100689069(Gnao1)
PLEU: 114694517(Gnao1)
NGI: 103749858(Gnao1)
HGL: 101723580(Gnao1)
CPOC: 100716648(Gnao1)
OCU: 100342283(GNAO1)
OPI: 101524943(GNAO1)
TUP: 102483059(GNAO1)
CFA: 609157(GNAO1)
VVP: 112929627(GNAO1)
VLG: 121496666(GNAO1)
AML: 100466130(GNAO1)
UAH: 113252256(GNAO1)
ORO: 101376297(GNAO1)
ELK: 111157367
MPUF: 101677157(GNAO1)
EJU: 114203550(GNAO1)
MLX: 118023770(GNAO1)
FCA: 101101353(GNAO1)
PYU: 121045329(GNAO1)
PBG: 122494226(GNAO1)
PTG: 102958483(GNAO1)
PPAD: 109270899(GNAO1)
AJU: 106973284(GNAO1)
HHV: 120232146(GNAO1)
BTA: 281792(GNAO1)
BOM: 102280695(GNAO1)
BIU: 109572786(GNAO1)
BBUB: 102394976(GNAO1)
CHX: 102186145(GNAO1)
ODA: 120873213(GNAO1)
CCAD: 122420097(GNAO1)
SSC: 100516976(GNAO1)
CFR: 102503533(GNAO1)
CBAI: 105078712(GNAO1)
CDK: 105096168(GNAO1)
BACU: 103011674(GNAO1)
LVE: 103091025(GNAO1)
OOR: 101284566(GNAO1)
DLE: 111165310(GNAO1)
PSIU: 116744142
ECB: 100051282(GNAO1)
EPZ: 103555391(GNAO1)
EAI: 106822188(GNAO1)
MYB: 102263380(GNAO1)
MYD: 102765603(GNAO1)
MMYO: 118674453(GNAO1)
MLF: 102438598
MNA: 107543463(GNAO1)
PKL: 118720475(GNAO1)
DRO: 112296672(GNAO1)
SHON: 118983964(GNAO1)
AJM: 119046437(GNAO1)
PDIC: 114488237(GNAO1)
MMF: 118639180(GNAO1)
RFQ: 117034411(GNAO1)
PALE: 102884654(GNAO1)
PGIG: 120617299(GNAO1)
RAY: 107499654(GNAO1)
TOD: 119249230(GNAO1)
LAV: 100658419(GNAO1)
TMU: 101357613
MDO: 100015137(GNAO1)
GAS: 123237302
SHR: 100914773(GNAO1)
PCW: 110193656(GNAO1)
OAA: 100079602(GNAO1)
GGA: 415698(GNAO1)
PCOC: 116243995(GNAO1)
CJO: 107319187(GNAO1)
NMEL: 110404455(GNAO1)
APLA: 101791437
ACYG: 106043102(GNAO1)
TGU: 100226617(GNAO1)
LSR: 110473008(GNAO1)
SCAN: 103816655(GNAO1)
PMOA: 120508016(GNAO1)
OTC: 121333824(GNAO1)
PRUF: 121348871(GNAO1)
GFR: 102040380(GNAO1)
PHI: 102101605(GNAO1)
PMAJ: 107209802(GNAO1)
CCW: 104687499(GNAO1)
FPG: 101920934(GNAO1)
FCH: 102052678(GNAO1)
EGZ: 104130276(GNAO1)
AROW: 112973913(GNAO1)
NPD: 112950566(GNAO1)
DNE: 112990422(GNAO1)
AMJ: 102575346(GNAO1)
CPOO: 109310332
GGN: 109289648(GNAO1)
CMY: 102938723(GNAO1)
CPIC: 101939865(GNAO1)
TST: 117886587(GNAO1)
CABI: 116827902(GNAO1)
MRV: 120384346(GNAO1)
ACS: 100561396(gnao1) 103282364
SUND: 121914189(GNAO1)
PMUR: 107296063(GNAO1)
PGUT: 117670323
PMUA: 114601900(GNAO1)
ZVI: 118085957(GNAO1)
GJA: 107118988(GNAO1)
XLA: 108714022 397896(gnao1.S)
XTR: 549749(gnao1)
NPR: 108793915(GNAO1)
DRE: 393760(gnao1a) 393801(gnao1b)
AMEX: 103039135(gnao1) 111191720
EEE: 113573596(gnao1) 113579128
TRU: 101079681(gnao1)
NCC: 104965823(gnao1)
ELY: 117252760(gnao1b) 117262875(gnao1a)
PLEP: 121949902(gnao1a) 121950142(gnao1b)
SLUC: 116046502(gnao1a) 116060644(gnao1b)
ECRA: 117949807 117951216(gnao1b)
PPUG: 119195856 119197056(gnao1b)
MSAM: 119889992 119893189(gnao1a)
CUD: 121508669(gnao1b) 121514716(gnao1a)
OAU: 116319550(gnao1a) 116334633(gnao1b)
OLA: 101166207(gnao1) 101167706
OML: 112152140 112160695(gnao1b)
GAF: 122836097 122843391(gnao1b)
CVG: 107103784
CTUL: 119789170(gnao1a) 119798936(gnao1b)
NFU: 107381402(gnao1) 107396198
KMR: 108228379(gnao1b) 108249535(gnao1a)
ALIM: 106532023(gnao1) 106536960
AOCE: 111571167 111579899(gnao1)
POV: 109636840(gnao1) 109638958
SSEN: 122772167(gnao1b) 122776356
HHIP: 117757375(gnao1b) 117762681(gnao1a)
SLAL: 111646261(gnao1) 111666045
XGL: 120789882(gnao1b) 120793703(gnao1a)
BPEC: 110169647(gnao1) 110175486
SASA: 106560843(gnao1) 106562227 106573727(gnao1) 106587424
OMY: 110494881(gnao1a) 110506557(gnao1b) 110520292 110526435
ELS: 105016280 105018488(gnao1)
SFM: 108918980(gnao1)
PKI: 111848107 111851926(gnao1)
LOC: 102691646(gnao1)
ARUT: 117424108
CMK: 103185959(gnao1b)
RTP: 109916540(gnao1)
BFO: 118417831
SCLV: 120332634
SPU: 576911
APLC: 110988978
SKO: 100377101
DME: Dmel_CG2204(Galphao)
DER: 6542262
DSE: 6608517
DSI: Dsimw501_GD10742(Dsim_GD10742)
DAN: 6496601
DSR: 110189779
DPE: 6592254
DWI: 6646234
DGR: 6560385
DAZ: 108615274
DNV: 108653373
DHE: 111599047
DVI: 6625542
CCAT: 101448728
BOD: 106622750
MDE: 101887825
SCAC: 106084632
LCQ: 111688088
ACOZ: 120953849
AARA: 120898335
AAG: 5570867
AALB: 109411098
CPII: 120431056
AME: 102656465
ACER: 108001957
BIM: 100742795
BBIF: 117215608
BVK: 117237634
BVAN: 117160146
BTER: 100642305
BPYO: 122576353
CCAL: 108632785
OBB: 114871500
MGEN: 117222370
NMEA: 116425370
CGIG: 122402212
SOC: 105195608
MPHA: 105830461
AEC: 105144590
ACEP: 105618355
PBAR: 105431709
VEM: 105569773
HST: 105185321
DQU: 106750083
CFO: 105253347
FEX: 115234505
LHU: 105678675
PGC: 109854118
OBO: 105282401
PCF: 106791593
PFUC: 122514368
VPS: 122634946
NVI: 100118592(Gnao)
CSOL: 105366809
TPRE: 106656646
MDL: 103569719
CGLO: 123259193
FAS: 105263862
DAM: 107043573
AGIF: 122861101
CCIN: 107275134
TCA: 655023
DPA: 109534130
ATD: 109599485
AGB: 108915123
LDC: 111508329
NVL: 108568503
PPYR: 116159057
OTU: 111416000
BMOR: 692460(Go)
MSEX: 115444215
BANY: 112053280
PMAC: 106716736
PPOT: 106102374
PXU: 106114246
PRAP: 110995785
ZCE: 119831909
HAW: 110371260
TNL: 113494761
PXY: 105383314
API: 100168757(Gnao1)
AGS: 114125074
RMD: 113550390
BTAB: 109038493
DCI: 103507425
CLEC: 106661135
HHAL: 106686446
NLU: 111061900
FOC: 113215994
ZNE: 110832380
CSEC: 111869440
FCD: 110863515
DPX: DAPPUDRAFT_59367(Gnao)
DMK: 116916730
PVM: 113824421
PJA: 122254127
HAME: 121875643
EAF: 111702108
DSV: 119436153
RSAN: 119371968
RMP: 119177116
VDE: 111243063
VJA: 111272392
TUT: 107359521
DPTE: 113798389
CSCU: 111620667
PTEP: 107443225
CEL: CELE_C26C6.2(goa-1) CELE_E02C12.5(gpa-3) CELE_F38E1.5(gpa-2) CELE_M04C7.1(gpa-15) CELE_R10H10.5(gpa-7) CELE_T19C4.6(gpa-1)
CBR: CBG_08377(Cbr-gpa-7) CBG_11277(Cbr-gpa-2) CBG_12520(Cbr-gpa-15) CBG_19263(Cbr-gpa-3) CBG_23127(Cbr-gpa-1) CBG_24698(Cbr-goa-1)
BMY: BM_BM3092(Bma-gpa-3) BM_BM8284(Bma-goa-1)
PCAN: 112553462
CRG: 105346725
MYI: 110453591
PMAX: 117338230
OBI: 106882189
OSN: 115216411
LAK: 106169108
EGL: EGR_07086
ATEN: 116298128
HMG: 100204078
TPS: THAPSDRAFT_264137(GPA2)
 » show all
Reference
PMID:1901650
  Authors
Tsukamoto T, Toyama R, Itoh H, Kozasa T, Matsuoka M, Kaziro Y
  Title
Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing.
  Journal
Proc Natl Acad Sci U S A 88:2974-8 (1991)
DOI:10.1073/pnas.88.8.2974
  Sequence
[hsa:2775]

DBGET integrated database retrieval system