KEGG   ORTHOLOGY: K04572
Entry
K04572                      KO                                     

Name
NEFL, NF-L
Definition
neurofilament light polypeptide
Pathway
ko05014  Amyotrophic lateral sclerosis (ALS)
Disease
H00264  Charcot-Marie-Tooth disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis (ALS)
    K04572  NEFL, NF-L; neurofilament light polypeptide
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04572  NEFL, NF-L; neurofilament light polypeptide
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K04572  NEFL, NF-L; neurofilament light polypeptide
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04572  NEFL, NF-L; neurofilament light polypeptide
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type IV
     K04572  NEFL, NF-L; neurofilament light polypeptide
Genes
HSA: 4747(NEFL)
PTR: 464063(NEFL)
PPS: 100993744(NEFL)
GGO: 101125225(NEFL)
PON: 100173482(NEFL)
NLE: 100607275(NEFL)
MCC: 641444(NEFL)
MCF: 101865563(NEFL)
CSAB: 103215500(NEFL)
RRO: 104673963(NEFL)
RBB: 108520451 108537813(NEFL)
CJC: 100409901(NEFL)
SBQ: 101053039(NEFL)
MMU: 18039(Nefl)
MCAL: 110309553(Nefl)
MPAH: 110325241(Nefl)
RNO: 83613(Nefl)
MUN: 110547754(Nefl)
CGE: 100774151(Nefl)
NGI: 103748085(Nefl)
HGL: 101704332(Nefl)
CCAN: 109677700(Nefl)
OCU: 100353082(NEFL)
TUP: 102494389(NEFL)
CFA: 100856220(NEFL)
VVP: 112926803(NEFL)
AML: 100482068(NEFL)
UMR: 103673297(NEFL)
UAH: 113269973(NEFL)
ORO: 101363767(NEFL)
ELK: 111155116
FCA: 101081039(NEFL)
PTG: 102952403(NEFL)
PPAD: 109277320(NEFL)
AJU: 106966531(NEFL)
BTA: 281348(NEFL)
BOM: 102285454(NEFL)
BIU: 109563142(NEFL)
BBUB: 102409722(NEFL)
CHX: 102179945(NEFL)
OAS: 101119539(NEFL)
SSC: 100521224(NEFL)
CFR: 102513324(NEFL)
CDK: 105102417(NEFL)
BACU: 102998493(NEFL)
LVE: 103069664(NEFL)
OOR: 101277008(NEFL)
DLE: 111185425(NEFL)
PCAD: 102975299(NEFL)
ECB: 100054178(NEFL)
EPZ: 103565657(NEFL)
EAI: 106826226(NEFL)
MYB: 102243832(NEFL)
MYD: 102754543(NEFL)
MNA: 107538044(NEFL)
HAI: 109391746(NEFL)
DRO: 112305208(NEFL)
PALE: 102881657(NEFL)
RAY: 107512531(NEFL)
MJV: 108405367(NEFL)
LAV: 100660580(NEFL)
TMU: 101351347
MDO: 100020093(NEFL)
SHR: 100933878(NEFL)
PCW: 110218453(NEFL)
OAA: 100077288(NEFL)
GGA: 419528(NEFL)
MGP: 100540661(NEFL)
CJO: 107323710(NEFL)
NMEL: 110387234(NEFL)
ACYG: 106048843(NEFL)
TGU: 100228028(NEFL)
LSR: 110480152(NEFL)
SCAN: 103822759(NEFL)
GFR: 102045204(NEFL)
FAB: 101810766(NEFL)
PHI: 102113970(NEFL)
PMAJ: 107213987(NEFL)
ETL: 114068770(NEFL)
FPG: 101918096(NEFL)
CLV: 102096160(NEFL)
NNI: 104019524(NEFL)
AAM: 106494151(NEFL)
ASN: 102387780(NEFL)
AMJ: 102564083(NEFL)
PSS: 102449258(NEFL)
CPIC: 101935191 101950453(NEFL)
ACS: 100563298(nefl)
PVT: 110070242(NEFL)
PBI: 103064356(NEFL)
PMUR: 107299067(NEFL)
TSR: 106549218(NEFL)
PMUA: 114585634(NEFL) 114604492
GJA: 107124342(NEFL)
XLA: 108712714(nefl.S) 397822(nefl.L)
XTR: 100216135(nefl)
NPR: 108794704(NEFL)
DRE: 321113(zgc:65851) 335380(si:dkey-33c12.3) 664698(neflb) 793912(nefla)
AMEX: 103044563(nefl)
RTP: 109931836
 » show all
Reference
  Authors
Perez-Olle R, Leung CL, Liem RK
  Title
Effects of Charcot-Marie-Tooth-linked mutations of the neurofilament light subunit on intermediate filament formation.
  Journal
J Cell Sci 115:4937-46 (2002)
DOI:10.1242/jcs.00148
  Sequence
[hsa:4747]

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