Entry
Symbol
GNAS
Name
guanine nucleotide-binding protein G(s) subunit alpha
Pathway
map04072 Phospholipase D signaling pathway
map04261 Adrenergic signaling in cardiomyocytes
map04270 Vascular smooth muscle contraction
map04750 Inflammatory mediator regulation of TRP channels
map04923 Regulation of lipolysis in adipocytes
map04925 Aldosterone synthesis and secretion
map04927 Cortisol synthesis and secretion
map04928 Parathyroid hormone synthesis, secretion and action
map04935 Growth hormone synthesis, secretion and action
map04961 Endocrine and other factor-regulated calcium reabsorption
map04962 Vasopressin-regulated water reabsorption
map05163 Human cytomegalovirus infection
map05207 Chemical carcinogenesis - receptor activation
Disease
H00244 Pseudohypoparathyroidism
H00441 Progressive osseous heteroplasia
H00501 Fibrous dysplasia, polyostotic
H02049 Bilateral macronodular adrenal hyperplasia
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04020 Calcium signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04072 Phospholipase D signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04024 cAMP signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09152 Endocrine system
04911 Insulin secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04922 Glucagon signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04923 Regulation of lipolysis in adipocytes
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04912 GnRH signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04913 Ovarian steroidogenesis
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04915 Estrogen signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04921 Oxytocin signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04926 Relaxin signaling pathway
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04935 Growth hormone synthesis, secretion and action
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04918 Thyroid hormone synthesis
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04928 Parathyroid hormone synthesis, secretion and action
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04916 Melanogenesis
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04924 Renin secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04925 Aldosterone synthesis and secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04927 Cortisol synthesis and secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04270 Vascular smooth muscle contraction
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09154 Digestive system
04970 Salivary secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04971 Gastric acid secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04972 Pancreatic secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04976 Bile secretion
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04961 Endocrine and other factor-regulated calcium reabsorption
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09156 Nervous system
04724 Glutamatergic synapse
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04728 Dopaminergic synapse
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04726 Serotonergic synapse
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04730 Long-term depression
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09158 Development and regeneration
04361 Axon regeneration
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09159 Environmental adaptation
04713 Circadian entrainment
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04714 Thermogenesis
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05207 Chemical carcinogenesis - receptor activation
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05165 Human papillomavirus infection
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09171 Infectious disease: bacterial
05110 Vibrio cholerae infection
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09174 Infectious disease: parasitic
05146 Amoebiasis
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05142 Chagas disease
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09164 Neurodegenerative disease
05012 Parkinson disease
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09165 Substance dependence
05030 Cocaine addiction
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05031 Amphetamine addiction
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05032 Morphine addiction
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
05034 Alcoholism
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09167 Endocrine and metabolic disease
04934 Cushing syndrome
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
04031 GTP-binding proteins
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
Exosome [BR:ko04147 ]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
Exosomal proteins of other body fluids (saliva and urine)
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
Exosomal proteins of colorectal cancer cells
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
Exosomal proteins of bladder cancer cells
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
GTP-binding proteins [BR:ko04031 ]
Heterotrimeric G-proteins
Alpha Subunits
Alpha type 2 (Gs)
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Mattera R, Codina J, Crozat A, Kidd V, Woo SL, Birnbaumer L
Title
Identification by molecular cloning of two forms of the alpha-subunit of the human liver stimulatory (GS) regulatory component of adenylyl cyclase.
Journal
Sequence
Reference
Authors
Wettschureck N, Offermanns S.
Title
Mammalian G proteins and their cell type specific functions.
Journal