KEGG   ORTHOLOGY: K04684
Entry
K04684                      KO                                     
Symbol
SP1
Name
transcription factor Sp1
Pathway
map01522  Endocrine resistance
map04137  Mitophagy - animal
map04350  TGF-beta signaling pathway
map04915  Estrogen signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05163  Human cytomegalovirus infection
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05224  Breast cancer
map05231  Choline metabolism in cancer
map05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K04684  SP1; transcription factor Sp1
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K04684  SP1; transcription factor Sp1
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04684  SP1; transcription factor Sp1
   04928 Parathyroid hormone synthesis, secretion and action
    K04684  SP1; transcription factor Sp1
   04927 Cortisol synthesis and secretion
    K04684  SP1; transcription factor Sp1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04684  SP1; transcription factor Sp1
   05202 Transcriptional misregulation in cancer
    K04684  SP1; transcription factor Sp1
   05231 Choline metabolism in cancer
    K04684  SP1; transcription factor Sp1
  09162 Cancer: specific types
   05224 Breast cancer
    K04684  SP1; transcription factor Sp1
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K04684  SP1; transcription factor Sp1
  09164 Neurodegenerative disease
   05016 Huntington disease
    K04684  SP1; transcription factor Sp1
   05017 Spinocerebellar ataxia
    K04684  SP1; transcription factor Sp1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K04684  SP1; transcription factor Sp1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04684  SP1; transcription factor Sp1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04684  SP1; transcription factor Sp1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04684  SP1; transcription factor Sp1
   03029 Mitochondrial biogenesis
    K04684  SP1; transcription factor Sp1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 SP/KLF family and related proteins
    K04684  SP1; transcription factor Sp1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Ubiquitas transcription factors
    K04684  SP1; transcription factor Sp1
Genes
HSA: 6667(SP1)
PTR: 451939(SP1)
PPS: 100985203(SP1)
GGO: 129525695(SP1)
PON: 100440745(SP1)
PPYG: 129009680(SP1)
NLE: 100585963(SP1)
HMH: 116481003(SP1)
SSYN: 129466125(SP1)
MCC: 702710(SP1)
MCF: 102115996(SP1)
MTHB: 126931105
MNI: 105474275(SP1)
CSAB: 103238395(SP1)
CATY: 105580268(SP1)
PANU: 116268873(SP1)
TGE: 112634626(SP1)
MLEU: 105554908(SP1)
RRO: 104670595(SP1)
RBB: 108521535(SP1)
TFN: 117090035(SP1)
PTEH: 111541933
CANG: 105503673(SP1)
CJC: 100407824(SP1)
SBQ: 101048381(SP1)
CIMI: 108284876(SP1)
ANAN: 105715866(SP1)
CSYR: 103260226
MMUR: 105870777(SP1)
LCAT: 123639764(SP1)
PCOQ: 105818043(SP1)
OGA: 100953042(SP1)
MMU: 20683(Sp1)
MCAL: 110310111(Sp1)
MPAH: 110334488(Sp1)
RNO: 24790(Sp1)
MCOC: 116080468(Sp1)
ANU: 117718542(Sp1)
MUN: 110552322(Sp1)
CGE: 100767199(Sp1)
MAUA: 101842935(Sp1)
PROB: 127226146(Sp1)
PLEU: 114696625(Sp1)
MFOT: 126491183
AAMP: 119823260(Sp1)
NGI: 103738561(Sp1)
HGL: 101697506(Sp1)
CPOC: 100726500(Sp1)
CCAN: 109684073(Sp1)
DORD: 105997935(Sp1)
DSP: 122124412(Sp1)
PLOP: 125364008(Sp1)
MMMA: 107148811(Sp1)
OCU: 100351317
OPI: 101533630(SP1)
TUP: 102473003(SP1)
GVR: 103592813(SP1)
CFA: 486507(SP1)
CLUD: 112667184(SP1)
VVP: 112921180(SP1)
VLG: 121479904(SP1)
NPO: 129517345(SP1)
AML: 100474983(SP1)
UMR: 103675530(SP1)
UAR: 123794698(SP1)
ELK: 111157856
LLV: 125106436
MPUF: 101686835(SP1)
MNP: 132019731(SP1)
MLK: 131838694(SP1)
NVS: 122892412(SP1)
ORO: 101367562(SP1)
EJU: 114225869(SP1)
ZCA: 113921297(SP1)
MLX: 118008792(SP1)
NSU: 110577393(SP1)
LWW: 102750952(SP1)
FCA: 101100227(SP1)
PYU: 121038490(SP1)
PCOO: 112867279(SP1)
PBG: 122473480(SP1)
PVIV: 125169758(SP1)
LRUF: 124502539
PTG: 102955984(SP1)
PPAD: 109249199(SP1)
PUC: 125919123
AJU: 106983094
HHV: 120247236(SP1)
BTA: 540741(SP1)
BOM: 102282294(SP1)
BIU: 109559035(SP1)
BBUB: 102392142(SP1)
BBIS: 105001581(SP1)
CHX: 100860911(SP1)
OAS: 101104139(SP1)
BTAX: 128047386(SP1)
ODA: 120858300(SP1)
CCAD: 122427132(SP1)
MBEZ: 129535764(SP1)
SSC: 396575(SP1)
CFR: 102520683(SP1)
CBAI: 105076285(SP1)
CDK: 105094564(SP1)
VPC: 102540803(SP1)
BACU: 103010578(SP1)
BMUS: 118901868(SP1)
OOR: 101284508(SP1)
DLE: 111173942(SP1)
PCAD: 102973166(SP1)
PSIU: 116760263(SP1)
NASI: 112394040(SP1)
ECB: 100629527(SP1)
EPZ: 103559402(SP1)
EAI: 106835289(SP1)
MYB: 102256096(SP1)
MYD: 102752526(SP1) 102753263
MMYO: 118650196(SP1)
MLF: 102419937(SP1)
MDT: 132227671(SP1)
PKL: 118728518(SP1)
EFUS: 103285347(SP1)
MNA: 107528307(SP1)
DRO: 112318338(SP1)
AJM: 119043517(SP1)
PDIC: 114513239(SP1)
PHAS: 123812402(SP1)
MMF: 118623453(SP1)
PPAM: 129084812(SP1)
HAI: 109391846(SP1)
RFQ: 117028359(SP1)
PALE: 102894100(SP1)
PGIG: 120602177(SP1)
PVP: 105302655(SP1)
RAY: 107509855(SP1)
MJV: 108394782(SP1)
TOD: 119247989(SP1)
SARA: 101550205(SP1)
SETR: 126022125(SP1)
LAV: 100662543(SP1)
TMU: 101349790
ETF: 101656971(SP1)
DNM: 101441960(SP1)
GAS: 123250447(SP1)
SHR: 100930024(SP1)
AFZ: 127539187
PCW: 110194006(SP1)
TVP: 118849909(SP1)
OAA: 114814764(SP1)
GGA: 395303(SP1)
PCOC: 116234959(SP1)
MGP: 100539328(SP1)
CJO: 107306967(SP1)
NMEL: 110390879(SP1)
ACYG: 106049581(SP1)
CATA: 118261637(SP1)
TGU: 115491349(SP1)
LSR: 110480534(SP1)
SCAN: 103825226(SP1)
PMOA: 120501829(SP1)
OTC: 121335576(SP1)
PRUF: 121356081(SP1)
FAB: 101818755(SP1)
OMA: 130265886(SP1)
PHI: 102112711(SP1)
PMAJ: 107198749(SP1)
CCAE: 111940460(SP1)
CBRC: 103620426(SP1)
ETL: 114072464(SP1)
ZLE: 135459071(SP1)
SVG: 106863620(SP1)
MMEA: 130586745(SP1)
HRT: 120764517(SP1)
SATI: 136372758(SP1)
FPG: 101921378(SP1)
FCH: 102046473(SP1)
CCRI: 104158086(SP1)
SHAB: 115618625(SP1)
ACUN: 113490686(SP1)
ACHC: 115350863(SP1)
HALD: 104320978(SP1)
HLE: 104830278(SP1)
AGEN: 126046439
CSTI: 104555928(SP1)
LDI: 104339751(SP1)
DPUB: 104309612(SP1)
EGZ: 104124794(SP1)
NNI: 104017530(SP1)
PADL: 103925632(SP1)
AFOR: 103898173(SP1)
FGA: 104074723(SP1)
GSTE: 104262017
CLV: 102091713(SP1)
MUI: 104541243(SP1)
PGUU: 104465949
PLET: 104619218(SP1)
CUCA: 104055651(SP1)
TEO: 104374672(SP1)
BREG: 104631946(SP1)
CPEA: 104397440(SP1)
RTD: 128903816(SP1)
AAM: 106487505(SP1)
AROW: 112961692(SP1)
NPD: 112952281(SP1)
DNE: 112996339(SP1)
SCAM: 104145526(SP1)
ASN: 102370562(SP1)
AMJ: 102557884(SP1)
CPOO: 109323220(SP1)
PSS: 102450768(SP1)
CMY: 102943070(SP1)
CCAY: 125627418(SP1)
DCC: 119845757(SP1)
CPIC: 101949432(SP1)
TST: 117888449(SP1)
CABI: 116828475(SP1)
MRV: 120391068(SP1)
ACS: 100553756(sp1)
ASAO: 132767660(SP1)
PVT: 110074383(SP1)
SUND: 121921686(SP1)
PBI: 103052107(SP1)
PMUR: 107291239(SP1)
CTIG: 120309973(SP1)
TSR: 106552859(SP1)
PGUT: 117662667(SP1)
APRI: 131189583(SP1)
PTEX: 113445573(SP1)
NSS: 113418432(SP1)
VKO: 123029773(SP1)
PMUA: 114593046(SP1)
PRAF: 128406725(SP1)
ZVI: 118077160(SP1)
HCG: 128342787(SP1)
GJA: 107119663(SP1)
EMC: 129346042(SP1)
XLA: 108709905(sp1.S) 431939(sp1.L)
XTR: 394744(sp1)
NPR: 108786826(SP1)
RTEM: 120929328(SP1)
BBUF: 120996097(SP1)
BGAR: 122930637(SP1)
MUO: 115466821(SP1)
GSH: 117357473(SP1)
DRE: 324109(sp1)
SRX: 107742020(sp1) 107748519
SGH: 107575074
CAUA: 113068116(sp1)
CGIB: 127967798
PTET: 122332822(sp1)
LROH: 127173298(sp1)
OMC: 131549245(sp1)
PPRM: 120483641(sp1)
RKG: 130086272(sp1)
MAMB: 125256370(sp1)
CIDE: 127522541
CERY: 137021797(sp1)
TROS: 130549521(sp1)
TDW: 130410424(sp1)
MANU: 129427237(sp1)
IPU: 108254785
IFU: 128624771(sp1)
PHYP: 113524457(sp1)
SMEO: 124402225(sp1)
TFD: 113643964(sp1)
TVC: 132838110(sp1)
TRN: 134301990(sp1)
AMEX: 103027197(sp1)
CMAO: 118799824(sp1)
EEE: 113581441(sp1)
CHAR: 105900246(sp1)
TRU: 101071233(sp1)
TFS: 130523796(sp1)
LCO: 104919961(sp1)
NCC: 104962038
TBEN: 117489446(sp1)
CGOB: 115008146(sp1)
PGEO: 117446848(sp1)
GACU: 117534246(sp1)
EMAC: 134883063(sp1)
ELY: 117256362(sp1)
EFO: 125898073(sp1)
PLEP: 121957297(sp1)
SLUC: 116051354(sp1)
ECRA: 117943581(sp1)
ESP: 116688600(sp1)
PFLV: 114554650(sp1)
GAT: 120835455(sp1)
PPUG: 119229581(sp1)
AFB: 129106444(sp1)
CLUM: 117731360(sp1)
PSWI: 130208812(sp1)
MSAM: 119885812(sp1)
SCHU: 122863200(sp1)
CUD: 121507071(sp1)
ALAT: 119020987(sp1)
MZE: 101477446(sp1)
ONL: 100690316(sp1)
OAU: 116320762(sp1)
OLA: 101161549(sp1)
OML: 112144742(sp1)
CSAI: 133448301(sp1)
XMA: 102236306(sp1)
XCO: 114134954(sp1)
XHE: 116710631(sp1)
PRET: 103464412(sp1)
PFOR: 103135891(sp1)
PLAI: 106956674(sp1)
PMEI: 106928483(sp1)
GAF: 122833402(sp1)
PPRL: 129355044(sp1)
CVG: 107103259(sp1)
CTUL: 119789679(sp1)
GMU: 124857569(sp1)
NFU: 107385320(sp1)
KMR: 108231465(sp1)
ALIM: 106514730(sp1)
NWH: 119411843(sp1)
AOCE: 111583780(sp1)
MCEP: 125006195(sp1)
CSEM: 103386384(sp1)
POV: 109635527(sp1)
SSEN: 122768811(sp1)
HHIP: 117761907(sp1)
HSP: 118105456(sp1)
PPLT: 128448542(sp1)
SMAU: 118309364(sp1)
LCF: 108884839
SDU: 111224016(sp1)
SLAL: 111670201(sp1)
XGL: 120807114(sp1)
HCQ: 109510616(sp1)
SSCV: 125977882
SBIA: 133507592(sp1)
PEE: 133408879(sp1)
PTAO: 133483239(sp1)
BPEC: 110171184(sp1)
MALB: 109959387(sp1)
BSPL: 114855393(sp1)
SJO: 128355965(sp1)
SASA: 106566174(sp1)
STRU: 115207322(sp1)
OTW: 112235852(sp1)
OMY: 110494799(sp1)
OGO: 124002635(sp1)
ONE: 115117400(sp1)
OKI: 109899785(sp1)
OKE: 118374681(sp1)
SALP: 112069701(sp1)
SNH: 120057948(sp1)
CCLU: 121574801(sp1)
ELS: 105031425(sp1)
SFM: 108928412(sp1)
PKI: 111835274(sp1)
AANG: 118208449 118211736(sp1)
LOC: 102682631
PSPA: 121308931(sp1)
PSEX: 120524944
LCM: 102366212(SP1)
CMK: 103190683
LERI: 129694994
TPRE: 106650949
 » show all
Reference
  Authors
Infantino V, Convertini P, Iacobazzi F, Pisano I, Scarcia P, Iacobazzi V
  Title
Identification of a novel Sp1 splice variant as a strong transcriptional activator.
  Journal
Biochem Biophys Res Commun 412:86-91 (2011)
DOI:10.1016/j.bbrc.2011.07.047
  Sequence
[hsa:6667]
Reference
  Authors
Ding H, Benotmane AM, Suske G, Collen D, Belayew A
  Title
Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene.
  Journal
J Biol Chem 274:19573-80 (1999)
DOI:10.1074/jbc.274.28.19573
  Sequence
[hsa:6667]

KEGG   ORTHOLOGY: K04448
Entry
K04448                      KO                                     
Symbol
JUN
Name
transcription factor AP-1
Pathway
map01522  Endocrine resistance
map04010  MAPK signaling pathway
map04012  ErbB signaling pathway
map04013  MAPK signaling pathway - fly
map04024  cAMP signaling pathway
map04137  Mitophagy - animal
map04210  Apoptosis
map04214  Apoptosis - fly
map04310  Wnt signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04530  Tight junction
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04624  Toll and Imd signaling pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04722  Neurotrophin signaling pathway
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05224  Breast cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04448  JUN; transcription factor AP-1
   04013 MAPK signaling pathway - fly
    K04448  JUN; transcription factor AP-1
   04012 ErbB signaling pathway
    K04448  JUN; transcription factor AP-1
   04310 Wnt signaling pathway
    K04448  JUN; transcription factor AP-1
   04668 TNF signaling pathway
    K04448  JUN; transcription factor AP-1
   04024 cAMP signaling pathway
    K04448  JUN; transcription factor AP-1
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K04448  JUN; transcription factor AP-1
  09143 Cell growth and death
   04210 Apoptosis
    K04448  JUN; transcription factor AP-1
   04214 Apoptosis - fly
    K04448  JUN; transcription factor AP-1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04448  JUN; transcription factor AP-1
   04530 Tight junction
    K04448  JUN; transcription factor AP-1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04624 Toll and Imd signaling pathway
    K04448  JUN; transcription factor AP-1
   04621 NOD-like receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04625 C-type lectin receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04660 T cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04658 Th1 and Th2 cell differentiation
    K04448  JUN; transcription factor AP-1
   04659 Th17 cell differentiation
    K04448  JUN; transcription factor AP-1
   04657 IL-17 signaling pathway
    K04448  JUN; transcription factor AP-1
   04662 B cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04448  JUN; transcription factor AP-1
   04915 Estrogen signaling pathway
    K04448  JUN; transcription factor AP-1
   04921 Oxytocin signaling pathway
    K04448  JUN; transcription factor AP-1
   04926 Relaxin signaling pathway
    K04448  JUN; transcription factor AP-1
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04448  JUN; transcription factor AP-1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04448  JUN; transcription factor AP-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04448  JUN; transcription factor AP-1
   05207 Chemical carcinogenesis - receptor activation
    K04448  JUN; transcription factor AP-1
   05208 Chemical carcinogenesis - reactive oxygen species
    K04448  JUN; transcription factor AP-1
   05203 Viral carcinogenesis
    K04448  JUN; transcription factor AP-1
   05231 Choline metabolism in cancer
    K04448  JUN; transcription factor AP-1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04448  JUN; transcription factor AP-1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04448  JUN; transcription factor AP-1
   05211 Renal cell carcinoma
    K04448  JUN; transcription factor AP-1
   05224 Breast cancer
    K04448  JUN; transcription factor AP-1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04448  JUN; transcription factor AP-1
   05170 Human immunodeficiency virus 1 infection
    K04448  JUN; transcription factor AP-1
   05161 Hepatitis B
    K04448  JUN; transcription factor AP-1
   05171 Coronavirus disease - COVID-19
    K04448  JUN; transcription factor AP-1
   05162 Measles
    K04448  JUN; transcription factor AP-1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04448  JUN; transcription factor AP-1
   05169 Epstein-Barr virus infection
    K04448  JUN; transcription factor AP-1
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04448  JUN; transcription factor AP-1
   05130 Pathogenic Escherichia coli infection
    K04448  JUN; transcription factor AP-1
   05132 Salmonella infection
    K04448  JUN; transcription factor AP-1
   05131 Shigellosis
    K04448  JUN; transcription factor AP-1
   05135 Yersinia infection
    K04448  JUN; transcription factor AP-1
   05133 Pertussis
    K04448  JUN; transcription factor AP-1
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K04448  JUN; transcription factor AP-1
   05142 Chagas disease
    K04448  JUN; transcription factor AP-1
  09163 Immune disease
   05323 Rheumatoid arthritis
    K04448  JUN; transcription factor AP-1
   05321 Inflammatory bowel disease
    K04448  JUN; transcription factor AP-1
  09165 Substance dependence
   05030 Cocaine addiction
    K04448  JUN; transcription factor AP-1
   05031 Amphetamine addiction
    K04448  JUN; transcription factor AP-1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04448  JUN; transcription factor AP-1
   05418 Fluid shear stress and atherosclerosis
    K04448  JUN; transcription factor AP-1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K04448  JUN; transcription factor AP-1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04448  JUN; transcription factor AP-1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04448  JUN; transcription factor AP-1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04448  JUN; transcription factor AP-1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    K04448  JUN; transcription factor AP-1
Genes
HSA: 3725(JUN)
PTR: 456893(JUN)
PPS: 100980908(JUN)
GGO: 101145729(JUN)
PON: 100450292(JUN)
PPYG: 129036837(JUN)
NLE: 100586501(JUN)
HMH: 116457363(JUN)
SSYN: 129458421(JUN)
MCC: 716452(JUN)
MCF: 102126446(JUN)
MTHB: 126962798
MNI: 105495146(JUN)
CSAB: 103224726(JUN)
CATY: 105595973(JUN)
PANU: 101010894(JUN)
TGE: 112619625(JUN)
MLEU: 105534921(JUN)
RRO: 104664278(JUN)
RBB: 108532921(JUN)
TFN: 117091985(JUN)
PTEH: 111523160(JUN)
CANG: 105511418(JUN)
CJC: 100400411(JUN)
SBQ: 101043809(JUN)
CIMI: 108314896(JUN)
ANAN: 105710356(JUN)
CSYR: 103274529(JUN)
MMUR: 105882585(JUN)
LCAT: 123635592(JUN)
PCOQ: 105806347(JUN)
OGA: 100965098(JUN)
MMU: 16476(Jun)
MCAL: 110292423(Jun)
MPAH: 110323252(Jun)
RNO: 24516(Jun)
MCOC: 116096245(Jun)
ANU: 117709069(Jun)
MUN: 110559727(Jun)
CGE: 113834001
MAUA: 101829259(Jun)
PROB: 127224952(Jun)
PLEU: 114693768(Jun)
MORG: 121448148(Jun)
MFOT: 126497948
AAMP: 119816694(Jun)
NGI: 103737138(Jun)
HGL: 101722197(Jun)
CPOC: 100728775(Jun)
CCAN: 109700777(Jun)
DSP: 122108943(Jun)
PLOP: 125355221(Jun)
MMMA: 107141712(Jun)
OCU: 100008856(JUN)
OPI: 101521685(JUN)
TUP: 102496870(JUN)
GVR: 103592390(JUN)
CFA: 609429(JUN)
CLUD: 112647115(JUN)
VVP: 112926091(JUN)
VLG: 121500205(JUN)
NPO: 129497811(JUN)
AML: 100483834(JUN)
UMR: 103670861(JUN)
UAH: 113254611(JUN)
UAR: 123795376(JUN)
ELK: 111143174
LLV: 125098159
MPUF: 101680348(JUN)
MNP: 132000935(JUN)
MLK: 131809019(JUN)
NVS: 122900023(JUN)
ORO: 101368207(JUN)
EJU: 114212152(JUN)
ZCA: 113939569(JUN)
MLX: 118019356(JUN)
NSU: 110575086(JUN)
LWW: 102727222(JUN)
FCA: 101097261(JUN)
PYU: 121027214(JUN)
PCOO: 112872218(JUN)
PBG: 122480569(JUN)
PVIV: 125173215(JUN)
LRUF: 124516273
PTG: 102958666(JUN)
PPAD: 109266785(JUN)
PUC: 125912547
AJU: 106974986
HHV: 120236252(JUN)
BTA: 280831(JUN)
BOM: 102267895(JUN)
BIU: 109556235(JUN)
BBUB: 102405224(JUN)
BBIS: 105000175(JUN)
CHX: 102185423(JUN)
OAS: 443219(JUN)
BTAX: 128044447(JUN)
ODA: 120857086(JUN)
CCAD: 122436906(JUN)
MBEZ: 129540610(JUN)
SSC: 396913(JUN)
CFR: 102516943(JUN)
CBAI: 105071674(JUN)
CDK: 105092850(JUN)
VPC: 102541687(JUN)
BMUS: 118901549(JUN)
LVE: 103071861(JUN)
OOR: 101288913(JUN)
DLE: 111175871(JUN)
PCAD: 102975458(JUN)
PSIU: 116761115(JUN)
NASI: 112407080(JUN)
ECB: 100067469(JUN)
EAI: 106833477(JUN)
MYB: 102260808(JUN)
MYD: 102752693(JUN) 107183844(JUNB)
MMYO: 118676104(JUN)
MLF: 102437415(JUN)
MDT: 132231012(JUN)
PKL: 118722794(JUN)
EFUS: 103284067(JUN)
MNA: 107536966(JUN)
DRO: 112314642(JUN)
SHON: 118984936(JUN)
AJM: 119051654(JUN)
PDIC: 114496428(JUN)
PHAS: 123831409(JUN)
MMF: 118627223(JUN)
PPAM: 129070771(JUN)
HAI: 109371251(JUN) 109371257
RFQ: 117027175(JUN)
PALE: 102896121(JUN)
PGIG: 120621837(JUN)
PVP: 105303436(JUN)
RAY: 107518352(JUN)
MJV: 108386817(JUN)
TOD: 119235421(JUN)
SETR: 126010979(JUN)
LAV: 100670432(JUN)
TMU: 101361653
ETF: 101656959(JUN)
DNM: 101412001(JUN)
MDO: 100018774(JUN)
GAS: 123247656(JUN)
SHR: 116423739(JUN)
AFZ: 127563247
PCW: 110212948(JUN)
TVP: 118848940(JUN)
GGA: 424673(JUN)
PCOC: 116235320(JUN)
MGP: 100548501(JUN)
CJO: 107317693(JUN)
TPAI: 128072448(JUN)
LMUT: 125693900(JUN)
NMEL: 110402812(JUN)
APLA: 101796626(JUN)
ACYG: 106032923(JUN)
CATA: 118243795(JUN)
AFUL: 116492142(JUN)
TGU: 100229914(JUN)
LSR: 110476957(JUN)
SCAN: 103815057(JUN)
PMOA: 120503126(JUN)
OTC: 121345151(JUN)
PRUF: 121361966(JUN)
GFR: 102039078(JUN)
FAB: 101816255(JUN)
OMA: 130256017(JUN)
PHI: 102112236(JUN)
PMAJ: 107208073(JUN)
CCAE: 111932998(JUN)
CCW: 104695158(JUN)
CBRC: 103615058(JUN)
ETL: 114055179(JUN)
ZAB: 102064401(JUN)
ZLE: 135451182(JUN)
SVG: 106849741(JUN)
MMEA: 130576048(JUN)
SATI: 136365098(JUN)
FPG: 101918818(JUN)
FCH: 102050406(JUN)
CCRI: 104166894(JUN)
NNT: 104401428(JUN)
SHAB: 115611576(JUN)
ACUN: 113482645(JUN)
TALA: 104356824(JUN)
ACHC: 115348746(JUN)
HALD: 104312836(JUN)
HLE: 104840987(JUN)
AGEN: 126041649
GCL: 127019308
CSTI: 104562831(JUN)
LDI: 104348545(JUN)
MNB: 103782384(JUN)
DPUB: 104301752(JUN)
AVIT: 104275215(JUN)
BRHI: 104496282(JUN)
EGZ: 104123944(JUN)
NNI: 104009262(JUN)
PCRI: 104026787(JUN)
PCAO: 104042855(JUN)
PADL: 103913320(JUN)
AFOR: 103905662(JUN)
FGA: 104072374(JUN)
GSTE: 104253202(JUN)
CLV: 102092209(JUN)
MUI: 104535854(JUN)
PGUU: 104462033(JUN)
PLET: 104622363(JUN)
EHS: 104505549(JUN)
CMAC: 104478878(JUND)
CUCA: 104066542(JUN)
TEO: 104371575
BREG: 104636702(JUN)
OHA: 104328027(JUN)
ACAR: 104520248(JUN)
CPEA: 104385160(JUN)
CVF: 104286046(JUN)
RTD: 128913682(JUN)
AAM: 106494500(JUN)
AROW: 112967663(JUN)
NPD: 112943557(JUN)
TGT: 104568780(JUN)
DNE: 112986058(JUN)
SCAM: 104152786(JUN)
ASN: 102374896(JUN)
AMJ: 102566064(JUN)
CPOO: 109307535(JUN)
GGN: 109286591(JUN)
PSS: 102455008(JUN)
CMY: 102937264(JUN)
CCAY: 125641435(JUN)
DCC: 119860735(JUN)
CPIC: 101930786(JUN)
TST: 117881919(JUN)
CABI: 116838113(JUN)
MRV: 120370011(JUN)
ACS: 100567718(jun)
ASAO: 132773982(JUN)
PVT: 110077124(JUN)
SUND: 121928905(JUN)
PBI: 103057921(JUN)
PMUR: 107302456(JUN)
CTIG: 120297354(JUN)
TSR: 106545185(JUN)
PGUT: 117664293(JUN)
APRI: 131193919(JUN)
PTEX: 113440637(JUN)
NSS: 113411064(JUN)
VKO: 123023503(JUN)
PMUA: 114598927(JUN)
PRAF: 128415701(JUN)
ZVI: 118089100(JUN)
HCG: 128324617(JUN)
GJA: 107111867(JUN)
STOW: 125433193(JUN)
EMC: 129329820(JUN)
XLA: 108700666 379050(jun.S) 399400(jun.L)
XTR: 100493911(jun)
NPR: 108788164(JUN)
RTEM: 120946091(JUN)
BBUF: 120979042(JUN)
BGAR: 122943208(JUN)
MUO: 115472249(JUN)
GSH: 117346700(JUN)
DRE: 335916(jun)
PTET: 122324581(jun) 122344965(june)
LROH: 127165315(june) 127183046(jun)
OMC: 131527636(jun) 131540839(june)
PPRM: 120471668(june) 120493498(jun)
RKG: 130076949(june) 130096106(jun)
MAMB: 125266201(june) 125279071(jun)
CERY: 137019377(jun) 137034610(june)
TROS: 130545711(june) 130565747(jun)
TDW: 130420161(june) 130434107(jun)
MANU: 129429389(jun) 129439457(june)
IPU: 108258130(jun) 108260086(june) 108267848
IFU: 128601161(jun) 128603833(june) 128610446
SMEO: 124377376(jun) 124378958(june) 124387939
TFD: 113641221(june) 113658727(jun) 113662252
TVC: 132841102(june) 132843425(jun) 132849017
TRN: 134303335(june) 134312443 134320007(jun)
AMEX: 103021920(june) 103026868(jun)
CMAO: 118814879(june) 118815433(jun)
CHAR: 105891385 105902506(june) 122131950(jun)
TRU: 101064806(jun) 101077059
TFS: 130517429(june) 130529159(jun) 130538932
TBEN: 117474460(june) 117488775 117496095(jun)
PGEO: 117445372(jun) 117455908(june) 117462217
GACU: 117545557 117555214(jun) 117557427(june)
EMAC: 134866042 134868643(june) 134869936(jun)
ELY: 117253294(jun) 117269419(june) 117271897
EFO: 125895951(jun) 125902348 125906209(june)
PLEP: 121951914 121960294(june) 121963101(jun)
SLUC: 116041404(june) 116045703 116058852(jun)
ECRA: 117949980(jun) 117953876 117959572(june)
GAT: 120815715 120824340(jun) 120831506(june)
PPUG: 119209630 119217222(jun) 119226243(june)
AFB: 129094375(jun) 129102849(june) 129110677
CLUM: 117740649(june) 117746578(jun)
PSWI: 130194485(jun) 130197944
MSAM: 119901002(jun) 119902398 119915034(june)
SCHU: 122865896(june) 122878280(jun) 122887568
CUD: 121512795(jun) 121520730 121524721(june)
ALAT: 119010619 119029038(jun) 119029448(june)
OAU: 116314808 116331225(jun) 116334108(june)
OML: 112144196(june) 112147409 112150898(jun)
XMA: 102230050(jun) 102234665
XCO: 114145916(jun) 114151264
PRET: 103463760 103478989(jun)
GAF: 122819303(june) 122839073(jun) 122841430
CVG: 107083648(jun) 107095895
CTUL: 119772327 119778327(june) 119799267(jun)
GMU: 124870122 124873148(june) 124873314(jun)
NFU: 107384375(jun) 107396464
KMR: 108230559(jun) 108238338
ALIM: 106521291(jun) 106534447
NWH: 119408007(jun) 119414431
AOCE: 111577530 111587627(jun)
MCEP: 124996826(junE) 125009453(jun) 125010340
CSEM: 103376719(jun) 103398819
POV: 109625845 109643961(jun)
SSEN: 122758027(june) 122762117(jun) 122770217
HSP: 118117519 118121433(jun) 118125425(june)
SMAU: 118285340(june) 118310771 118317957(jun)
LCF: 108879142(jun) 108883834
SDU: 111228982(jun) 111231968
XGL: 120791293(jun) 120799405
SBIA: 133491200(june) 133503311(jun) 133510484
PEE: 133406080(jun) 133411290 133413725(june)
PTAO: 133465148(june) 133481114(jun) 133488582
BPEC: 110154702(jun) 110173458
MALB: 109952420 109970646(jun)
BSPL: 114844877 114854282(jun) 114867319(june)
SJO: 128362425(jun) 128368559 128380084(june)
AANG: 118212138(june) 118226519(jun)
LOC: 102689161 102693762(jun)
PSEX: 120514504(jun) 120533062(june)
LCM: 102350279(JUN) 102358101
CMK: 103185297(jun)
RTP: 109925743(jun)
CPLA: 122554377(jun)
HOC: 132818750(jun)
LERI: 129700980(jun)
BFO: 118431712
BBEL: 109475262
CIN: 778972(jun)
SCLV: 120347297
LPIC: 129270980
APLC: 110977802
ARUN: 117298071
AJC: 117112403
SKO: 100313553
DME: Dmel_CG2275(Jra)
DER: 6541513
DSE: 6608460
DSI: Dsimw501_GD15385(Dsim_GD15385)
DAN: 6494876
DSR: 110178000
DPO: 4804559
DPE: 6592569
DMN: 108160413
DWI: 6640122
DGR: 6560997
DAZ: 108617394
DNV: 108654006
DVI: 6626359
CCAT: 101461665
BOD: 106627234
BDR: 105226243
RZE: 108372977
AOQ: 129245167
TDA: 119681596
MDE: 101896731
SCAC: 106092172
LCQ: 111688738
LSQ: 119616294
GFS: 119639762
ECOE: 129950312
CLON: 129607372
HIS: 119646883
AGA: 1276998
ACOZ: 120953126
AARA: 120897200
AMER: 121592593
AFUN: 125772001
AMOU: 128303514
AALI: 118466810
AAG: 5578266
AALB: 109408179
ASUA: 134211617
CPII: 120418815
CNS: 116350146
BCOO: 119073609
AME: 726289
ACER: 107997545
ALAB: 122713516
ADR: 102671896
AFLR: 100872357
BIM: 100750048
BBIF: 117207147
BVK: 117234017
BVAN: 117154905
BTER: 100645950
BAFF: 126920213
BPYO: 122570728
BPAS: 132906288
FVI: 122536692
CCAL: 108627361
OBB: 114875381
OLG: 117604570
MGEN: 117217542
NMEA: 116429394
CGIG: 122396769
SOC: 105200133
MPHA: 105830524
AEC: 105155106
ACEP: 105621323
PBAR: 105428867
VEM: 105565543
HST: 105190515
DQU: 106744297
CFO: 105253340
FEX: 115236485
LHU: 105671646(Jra)
PGC: 109856529
OBO: 105277703
NVI: 100123087
CSOL: 105368040
LHT: 122499944
LBD: 127290486
MDL: 103568136
CGLO: 123263167
FAS: 105268795
DAM: 107036330
AGIF: 122860897
CINS: 118066645
VCAN: 122415950
CCIN: 107273385
DSM: 124416567
NPT: 124212074
NFB: 124188195
NLO: 107216672
NVG: 124297960
AROA: 105684483
TCA: 663937(Jra)
DPA: 109542182
SOY: 115878834
AGRG: 126734866
ATD: 109593897
CSET: 123316336
AGB: 111691268
LDC: 111517409
DVV: 114334465
NVL: 108557779
OTU: 111426302
BMOR: 101736835
BMAN: 114249964
MSEX: 115452083
BANY: 112047037
MJU: 123875541
NIQ: 126775178
VCD: 124537220
MCIX: 123661352
PMAC: 106715838
PPOT: 106102499
PXU: 106114386
PRAP: 110996297
PBX: 123716299
PNAP: 125048584
ZCE: 119832097
CCRC: 123699147
LSIN: 126978009
AAGE: 121737480
HAW: 110381290
HZE: 124638169
TNL: 113505301
SLIU: 111363758
OFU: 114364772
ATRA: 106139341
GMW: 113521578
PXY: 105388607
PGW: 126374442
LGLY: 125234718
CFEL: 113376948
DNX: 107166782
AGS: 114122336
RMD: 113557503
ACOO: 126840342
DVT: 126904292
BTAB: 109035563
DCI: 103519231
HHAL: 106689606(Jra) 106691817
FOC: 113207279
TPAL: 117648238
ZNE: 110827968
CSEC: 111864826
BROR: 134540393
IEL: 124157984
FCD: 110859845
DMK: 116916511
DPZ: 124337910
PVM: 113800779
PJA: 122255148
PMOO: 119586281
HAME: 121879991
PCLA: 123757183
CQD: 128692679
MNZ: 135200814
EAF: 111700297
PPOI: 119112496
VDE: 111243751
VJA: 111265619
TUT: 107364868
DPTE: 113799532
PMEO: 129599870
BMY: BM_BM5997(Bma-jun-1)
PVUL: 126817537
PCAN: 112574619
BGT: 106064986
GAE: 121376293
HRF: 124111118
HRJ: 124253796
CRG: 105341654
CANU: 128165517
CVN: 111120138
OED: 125671487
PMAX: 117325996
MCAF: 127732995
MMER: 123525225
RPHI: 132747571
DPOL: 127850333
MAEA: 128214773
OBI: 106868153
OSN: 115214910
LJP: 135470645
LAK: 106165046
LLON: 135487201
HMG: 100204820(jun) 105851038
RES: 135689783
AQU: 100640297
 » show all
Reference
  Authors
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D
  Title
The oncogene c-Jun impedes somatic cell reprogramming.
  Journal
Nat Cell Biol 17:856-67 (2015)
DOI:10.1038/ncb3193
Reference
PMID:3194415
  Authors
Hattori K, Angel P, Le Beau MM, Karin M
  Title
Structure and chromosomal localization of the functional intronless human JUN protooncogene.
  Journal
Proc Natl Acad Sci U S A 85:9148-52 (1988)
DOI:10.1073/pnas.85.23.9148
  Sequence
[hsa:3725]

KEGG   ORTHOLOGY: K04379
Entry
K04379                      KO                                     
Symbol
FOS
Name
proto-oncogene protein c-fos
Pathway
map01522  Endocrine resistance
map04010  MAPK signaling pathway
map04024  cAMP signaling pathway
map04210  Apoptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04713  Circadian entrainment
map04725  Cholinergic synapse
map04728  Dopaminergic synapse
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map04928  Parathyroid hormone synthesis, secretion and action
map04932  Non-alcoholic fatty liver disease
map04935  Growth hormone synthesis, secretion and action
map05031  Amphetamine addiction
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05224  Breast cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05323  Rheumatoid arthritis
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04668 TNF signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04024 cAMP signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04379  FOS; proto-oncogene protein c-fos
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04660 T cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04658 Th1 and Th2 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04659 Th17 cell differentiation
    K04379  FOS; proto-oncogene protein c-fos
   04657 IL-17 signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04662 B cell receptor signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04917 Prolactin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04921 Oxytocin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04926 Relaxin signaling pathway
    K04379  FOS; proto-oncogene protein c-fos
   04935 Growth hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
   04928 Parathyroid hormone synthesis, secretion and action
    K04379  FOS; proto-oncogene protein c-fos
  09156 Nervous system
   04725 Cholinergic synapse
    K04379  FOS; proto-oncogene protein c-fos
   04728 Dopaminergic synapse
    K04379  FOS; proto-oncogene protein c-fos
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04379  FOS; proto-oncogene protein c-fos
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04379  FOS; proto-oncogene protein c-fos
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05207 Chemical carcinogenesis - receptor activation
    K04379  FOS; proto-oncogene protein c-fos
   05208 Chemical carcinogenesis - reactive oxygen species
    K04379  FOS; proto-oncogene protein c-fos
   05231 Choline metabolism in cancer
    K04379  FOS; proto-oncogene protein c-fos
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04379  FOS; proto-oncogene protein c-fos
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04379  FOS; proto-oncogene protein c-fos
   05224 Breast cancer
    K04379  FOS; proto-oncogene protein c-fos
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05170 Human immunodeficiency virus 1 infection
    K04379  FOS; proto-oncogene protein c-fos
   05161 Hepatitis B
    K04379  FOS; proto-oncogene protein c-fos
   05171 Coronavirus disease - COVID-19
    K04379  FOS; proto-oncogene protein c-fos
   05162 Measles
    K04379  FOS; proto-oncogene protein c-fos
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04379  FOS; proto-oncogene protein c-fos
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04379  FOS; proto-oncogene protein c-fos
   05132 Salmonella infection
    K04379  FOS; proto-oncogene protein c-fos
   05135 Yersinia infection
    K04379  FOS; proto-oncogene protein c-fos
   05133 Pertussis
    K04379  FOS; proto-oncogene protein c-fos
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K04379  FOS; proto-oncogene protein c-fos
   05142 Chagas disease
    K04379  FOS; proto-oncogene protein c-fos
  09163 Immune disease
   05323 Rheumatoid arthritis
    K04379  FOS; proto-oncogene protein c-fos
  09165 Substance dependence
   05031 Amphetamine addiction
    K04379  FOS; proto-oncogene protein c-fos
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
   05418 Fluid shear stress and atherosclerosis
    K04379  FOS; proto-oncogene protein c-fos
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K04379  FOS; proto-oncogene protein c-fos
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04379  FOS; proto-oncogene protein c-fos
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04379  FOS; proto-oncogene protein c-fos
   04131 Membrane trafficking
    K04379  FOS; proto-oncogene protein c-fos
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    K04379  FOS; proto-oncogene protein c-fos
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    K04379  FOS; proto-oncogene protein c-fos
Genes
HSA: 2353(FOS)
PTR: 453047(FOS)
PPS: 100987957(FOS)
GGO: 101127590(FOS)
PON: 100462290(FOS)
PPYG: 129012966(FOS)
NLE: 100585899(FOS)
HMH: 116456218(FOS)
SSYN: 129487641(FOS)
MCC: 702077(FOS)
MCF: 102143716(FOS)
MTHB: 126959543
MNI: 105495778(FOS)
CSAB: 103229352(FOS)
CATY: 105590868(FOS)
PANU: 101021141(FOS)
TGE: 112628560(FOS)
MLEU: 105540805(FOS)
RRO: 104677590(FOS)
RBB: 108534930(FOS)
TFN: 117069314(FOS)
PTEH: 111521118(FOS)
CANG: 105517139(FOS)
CJC: 100390054(FOS)
SBQ: 101046701(FOS)
CIMI: 108304440(FOS)
ANAN: 105707245(FOS)
CSYR: 103266527(FOS)
MMUR: 105858849(FOS)
LCAT: 123646534(FOS)
PCOQ: 105819831(FOS)
OGA: 100953435(FOS)
MMU: 14281(Fos)
MCAL: 110307063(Fos)
MPAH: 110324365(Fos)
RNO: 314322(Fos)
MCOC: 116080518(Fos)
ANU: 117697448(Fos)
MUN: 110546962(Fos)
CGE: 100689418(Fos)
MAUA: 101831721(Fos)
PROB: 127230991(Fos)
PLEU: 114698038(Fos)
MORG: 121452580(Fos)
MFOT: 126515189
AAMP: 119819161(Fos)
NGI: 103747342(Fos)
HGL: 101718383(Fos)
CPOC: 100713572(Fos)
CCAN: 109694000(Fos)
DORD: 105986734(Fos)
DSP: 122118881(Fos)
PLOP: 125363230(Fos)
NCAR: 124977967
MMMA: 107149351(Fos)
OCU: 100338345
OPI: 101526067(FOS)
TUP: 102491199(FOS)
GVR: 103605891(FOS)
CFA: 490792(FOS)
CLUD: 112657374(FOS)
VVP: 112927292(FOS)
VLG: 121493811(FOS)
NPO: 129496401(FOS)
AML: 100474867(FOS)
UMR: 103671011(FOS)
UAH: 113270317(FOS)
UAR: 123798968(FOS)
ELK: 111148602
LLV: 125105343
MPUF: 101685236(FOS)
MNP: 132000157(FOS)
MLK: 131836857(FOS)
NVS: 122893478(FOS)
ORO: 101366773(FOS)
EJU: 114207358(FOS)
ZCA: 113910278(FOS)
MLX: 118002212(FOS)
NSU: 110571456(FOS)
LWW: 102727855(FOS)
FCA: 493935(FOS)
PYU: 121032071(FOS)
PCOO: 112854981(FOS)
PBG: 122469346(FOS)
PVIV: 125168871(FOS)
LRUF: 124512631
PTG: 102952769(FOS)
PPAD: 109253856(FOS)
PUC: 125909334
AJU: 106974355
HHV: 120231952(FOS)
BTA: 280795(FOS)
BOM: 102275053(FOS)
BIU: 109565363(FOS)
BBUB: 102393791(FOS)
BBIS: 105000057(FOS)
CHX: 102171520(FOS)
OAS: 443218(FOS)
BTAX: 128053951(FOS)
ODA: 120852702(FOS)
CCAD: 122443873(FOS)
MBEZ: 129563123(FOS)
SSC: 100144486(FOS)
CFR: 102519397(FOS)
CBAI: 105075289(FOS)
CDK: 105086086(FOS)
VPC: 102533186(FOS)
BACU: 102997242(FOS)
BMUS: 118890999(FOS)
LVE: 103072956 103084433(FOS)
OOR: 101286650(FOS)
DLE: 111176238(FOS)
PCAD: 102982453(FOS)
PSIU: 116749519(FOS)
NASI: 112394907(FOS)
ECB: 100051632(FOS)
EPZ: 103548618(FOS)
EAI: 106827712(FOS)
MYB: 102246307(FOS)
MYD: 102764239(FOS)
MMYO: 118658230(FOS)
MLF: 102417433(FOS)
MDT: 132231259(FOS)
PKL: 118715156(FOS)
EFUS: 103283560(FOS)
MNA: 107533821(FOS)
DRO: 112311412(FOS)
SHON: 118976823(FOS)
AJM: 119049259(FOS)
PDIC: 114493153(FOS)
PHAS: 123808226(FOS)
MMF: 118618599(FOS)
PPAM: 129065732(FOS)
HAI: 109381526(FOS)
RFQ: 117024158(FOS)
PALE: 102891428(FOS)
PGIG: 120619517(FOS)
PVP: 105299213(FOS)
RAY: 107498912(FOS)
MJV: 108402534(FOS)
TOD: 119238328(FOS)
SARA: 101545059(FOS)
SETR: 126004042(FOS)
LAV: 100674799(FOS)
TMU: 101357016
ETF: 101656124(FOS)
DNM: 101431782(FOS)
MDO: 100018285(FOS)
GAS: 123237804(FOS)
SHR: 100924435(FOS)
AFZ: 127549484
PCW: 110208312(FOS)
TVP: 118829992(FOS)
OAA: 100075021(FOS)
GGA: 396512(FOS)
PCOC: 116229416(FOS)
MGP: 104916287
CJO: 107315165(FOS)
TPAI: 128086968(FOS)
LMUT: 125695245(FOS)
NMEL: 110400992(FOS)
APLA: 101801698(FOS)
ACYG: 106038794(FOS)
CATA: 118244473(FOS)
AFUL: 116489845(FOS)
TGU: 100222961(FOS)
LSR: 110477175(FOS)
SCAN: 103826521(FOS)
PMOA: 120500400(FOS)
OTC: 121333162(FOS)
PRUF: 121355973(FOS)
GFR: 102037526(FOS)
FAB: 101807505(FOS)
OMA: 130266853(FOS)
PHI: 102103181(FOS)
PMAJ: 107206453(FOS)
CCAE: 111945660(FOS)
CCW: 104685225(FOS)
ETL: 114056015(FOS)
ZLE: 135448975(FOS)
SVG: 106861661(FOS)
MMEA: 130578704(FOS)
HRT: 120754638(FOS)
SATI: 136363007(FOS)
FPG: 101921708(FOS)
SHAB: 115606485(FOS)
ACUN: 113480870(FOS)
TALA: 116959628(FOS)
ACHC: 115333806(FOS)
HLE: 104841955(FOS)
AGEN: 126049369
GCL: 127017203
DPUB: 104308225(FOS)
BRHI: 104501378(FOS)
CLV: 102098648(FOS)
CUCA: 128852401(FOS)
RTD: 128909213(FOS)
AAM: 106483057(FOS)
AROW: 112960526(FOS)
NPD: 112957980(FOS)
TGT: 104579149(FOS)
DNE: 112995446(FOS)
ASN: 102385076(FOS)
AMJ: 102562416(FOS)
CPOO: 109321539(FOS)
GGN: 109299320(FOS)
PSS: 102454531(FOS)
CMY: 102940899(FOS)
CCAY: 125638512(FOS)
DCC: 119857951(FOS)
CPIC: 101937366(FOS)
TST: 117876830(FOS)
CABI: 116837497(FOS)
MRV: 120405405(FOS)
ACS: 100556427(fos)
ASAO: 132764361(FOS)
PVT: 110079111(FOS)
SUND: 121918920(FOS)
PBI: 103049145(FOS)
PMUR: 107285955(FOS)
CTIG: 120311766(FOS)
TSR: 106545095(FOS)
PGUT: 117665838(FOS)
APRI: 131187775(FOS)
PTEX: 113443590(FOS)
NSS: 113410033(FOS)
VKO: 123026796(FOS)
PMUA: 114591829(FOS)
PRAF: 128408950(FOS)
ZVI: 118081801(FOS)
HCG: 128340943(FOS)
GJA: 107118325(FOS)
STOW: 125427132(FOS)
EMC: 129325320(FOS)
XLA: 108698676(fos.L) 447201(fos.S)
XTR: 548954(fos)
NPR: 108802481(FOS)
RTEM: 120920284(FOS)
BBUF: 120982209(FOS)
BGAR: 122923800(FOS)
MUO: 115477396(FOS)
GSH: 117364307(FOS)
DRE: 394198(fosab) 564403(si:ch211-153j24.3) 570238(fosaa)
PTET: 122324473(si:ch211-153j24.3) 122325196(fosab) 122361624(fosaa)
LROH: 127179306(fosaa) 127183261(fosab) 127183262(si:ch211-153j24.3)
OMC: 131523270(fosaa) 131526674(fosab) 131526675(si:ch211-153j24.3)
PPRM: 120460309(si:ch211-153j24.3) 120460310(fosab) 120462345(fosaa)
RKG: 130076711(fosaa) 130103126(fosab) 130103127(si:ch211-153j24.3)
MAMB: 125268283(fosaa) 125278491(fosab) 125278492(si:ch211-153j24.3)
CIDE: 127498056 127502293 127502294(si:ch211-153j24.3)
CERY: 137006970(fosaa) 137019192(fosab) 137019193(si:ch211-153j24.3)
TROS: 130560085(fosaa) 130566284(si:ch211-153j24.3) 130566285(fosab)
TDW: 130434283(fosab) 130434596(si:ch211-153j24.3) 130436958(fosaa)
MANU: 129418294(fosaa) 129429927(fosab) 129429929(si:ch211-153j24.3)
IPU: 108255380(si:ch211-153j24.3) 108260991(fosab) 108269548(fosaa) 108278451(fosl1b)
IFU: 128612582(fosaa) 128616521(si:ch211-153j24.3) 128618142(fosab)
SMEO: 124390622(fosaa) 124401612(si:ch211-153j24.3) 124401616(fosab)
TFD: 113651743(si:ch211-153j24.3) 113651782(fosab) 113659351(fosaa)
TVC: 132852110(fosaa) 132854711(si:ch211-153j24.3) 132855121(fosab)
TRN: 134319796(fosab) 134320503(si:ch211-153j24.3) 134325251
AMEX: 103036705(fosaa) 103042954(si:ch211-153j24.3) 103043278(fosab) 107197750(fosl1b)
CMAO: 118816011(fosab) 118816012(si:ch211-153j24.3) 118823609(fosaa)
CHAR: 105889778(si:ch211-153j24.3) 105889814(fosab) 105893125(fosaa)
TFS: 130516370(fosab) 130516371(si:ch211-153j24.3) 130540365(fosaa)
TBEN: 117471609(fosaa) 117493227(si:ch211-153j24.3) 117493507(fosab)
PGEO: 117440361(si:ch211-153j24.3) 117440362(fosab) 117468017
GACU: 117533795(fosab) 117533803 117549989(fosaa)
EMAC: 134876857 134876858(fosab) 134881848(fosaa)
ELY: 117270660 117270661(fosab)
EFO: 125896733 125896734(fosab)
SLUC: 116035578(fosaa) 116066178 116066292(fosab)
CLUM: 117725194(fosaa) 117727586 117727588(fosab)
PSWI: 130201320(fosaa) 130202564(fosab) 130202820
SCHU: 122862302(fosaa) 122862755(fosab) 122862756(si:ch211-153j24.3)
CUD: 121520963(fosab) 121521743(si:ch211-153j24.3) 121526444(fosaa)
OAU: 116313320(fosaa) 116314098 116314100(fosab)
OML: 112150122(fosaa) 112158236(fosab) 112158237
CSAI: 133418335(fosab) 133462543(fosaa) 133464900
CTUL: 119785058(fosab) 119785064(si:ch211-153j24.3) 119787546(fosaa)
KMR: 108233178(fosaa) 108242438(fosab) 108242442(si:ch211-153j24.3)
NWH: 119418187(fosab) 119418189 119427921(fosaa)
HHIP: 117756645(fosaa) 117758243 117758245(fosab)
SMAU: 118286690(fosaa) 118290484(si:ch211-153j24.3) 118290485(fosab)
LCF: 108892487(fosaa) 108895610(si:ch211-153j24.3) 108895611(fosab)
XGL: 120789178 120789444(fosab) 120795587(fosaa)
SSCV: 125981396 125990318 125990320(si:ch211-153j24.3)
SBIA: 133513222
PEE: 133412738(fosaa) 133417283(fosab) 133417284
PTAO: 133468338 133468339(fosab) 133487442(fosaa)
SJO: 128375379(fosaa)
LOC: 102690879(fos) 102691085
PSEX: 120518579(fosab) 120518863
LCM: 102361375(FOS)
CMK: 103189966(fos)
RTP: 109925076
CPLA: 122555597
HOC: 132818022
LERI: 129700096
BBEL: 109471128
CIN: 778607(fos)
SCLV: 120330856
TPRE: 106657453
AGIF: 122855774
CSET: 123309148
AGB: 108911388
APLN: 108738749
PPYR: 116170767
BANY: 112058375
MCIX: 123662558
OFU: 114360018
CQD: 128697682
PPOI: 119109083
DSV: 119457699
RSAN: 119373388
RMP: 119167126
BGT: 106063678
HRJ: 124268854
OED: 125649072
MMER: 123537144
OSN: 115222465
 » show all
Reference
  Authors
Vesely PW, Staber PB, Hoefler G, Kenner L
  Title
Translational regulation mechanisms of AP-1 proteins.
  Journal
Mutat Res 682:7-12 (2009)
DOI:10.1016/j.mrrev.2009.01.001
Reference
PMID:6574479
  Authors
van Straaten F, Muller R, Curran T, Van Beveren C, Verma IM
  Title
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.
  Journal
Proc Natl Acad Sci U S A 80:3183-7 (1983)
DOI:10.1073/pnas.80.11.3183
  Sequence
[hsa:2353]
Reference
  Authors
Portal MM, Ferrero GO, Caputto BL
  Title
N-Terminal c-Fos tyrosine phosphorylation regulates c-Fos/ER association and c-Fos-dependent phospholipid synthesis activation.
  Journal
Oncogene 26:3551-8 (2007)
DOI:10.1038/sj.onc.1210137
  Sequence
[hsa:2353]

DBGET integrated database retrieval system