KEGG   ORTHOLOGY: K04936
Entry
K04936                      KO                                     

Name
KCNMA1, KCA1.1
Definition
potassium large conductance calcium-activated channel subfamily M alpha member 1
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
ko04924  Renin secretion
ko04970  Salivary secretion
ko04972  Pancreatic secretion
Disease
H01258  Generalized epilepsy and paroxysmal dyskinesia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
   04924 Renin secretion
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
  09154 Digestive system
   04970 Salivary secretion
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
   04972 Pancreatic secretion
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04936  KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
Other DBs
GO: 0015269
TC: 1.A.1.3.1 1.A.1.3.2 1.A.1.3.3
Genes
HSA: 3778(KCNMA1)
PTR: 466115(KCNMA1)
PPS: 100978771(KCNMA1)
GGO: 101153410(KCNMA1)
NLE: 100589545(KCNMA1)
MCC: 574103(KCNMA1)
MCF: 102139202(KCNMA1)
CSAB: 103215949(KCNMA1)
RRO: 104662238(KCNMA1)
RBB: 108529255(KCNMA1)
CJC: 100402638(KCNMA1)
SBQ: 101035009(KCNMA1)
MMU: 16531(Kcnma1)
MCAL: 110309908(Kcnma1)
MPAH: 110325018(Kcnma1)
RNO: 83731(Kcnma1)
MUN: 110562795(Kcnma1)
CGE: 100764731(Kcnma1)
NGI: 103747438(Kcnma1)
HGL: 101726007(Kcnma1)
CCAN: 109684792
OCU: 100008745(KCNMA1)
TUP: 102471296(KCNMA1)
CFA: 403984(KCNMA1)
VVP: 112924709(KCNMA1)
AML: 100473263(KCNMA1)
UMR: 103668030(KCNMA1)
UAH: 113259211(KCNMA1)
ORO: 101374985(KCNMA1)
ELK: 111144685
FCA: 101099080(KCNMA1)
PTG: 102949074(KCNMA1)
PPAD: 109264456(KCNMA1)
AJU: 106969710(KCNMA1)
BTA: 282573(KCNMA1)
BOM: 102270859(KCNMA1)
BIU: 109553636(KCNMA1)
BBUB: 102397404(KCNMA1)
CHX: 102186276(KCNMA1)
OAS: 100270685(KCNMA1)
SSC: 397434(KCNMA1)
CFR: 102509654(KCNMA1)
CDK: 105092432(KCNMA1)
BACU: 103020151(KCNMA1)
LVE: 103072349
OOR: 101271854(KCNMA1)
DLE: 111183580(KCNMA1)
PCAD: 102986016(KCNMA1)
ECB: 100064366(KCNMA1)
EPZ: 103550311(KCNMA1)
EAI: 106828419(KCNMA1)
MYB: 102242737(KCNMA1)
MYD: 102763054(KCNMA1)
MNA: 107545799(KCNMA1)
HAI: 109390493(KCNMA1)
DRO: 112305509(KCNMA1)
PALE: 102894757(KCNMA1)
RAY: 107518064(KCNMA1)
LAV: 100656201(KCNMA1)
TMU: 101341595
MDO: 100013395(KCNMA1)
SHR: 100922504(KCNMA1)
PCW: 110221426(KCNMA1)
OAA: 100079144(KCNMA1)
GGA: 374065(KCNMA1)
MGP: 100550498(KCNMA1)
CJO: 107315852(KCNMA1)
NMEL: 110399692(KCNMA1)
APLA: 101792241(KCNMA1)
ACYG: 106032783(KCNMA1)
TGU: 100227091(KCNMA1)
LSR: 110471744(KCNMA1)
SCAN: 103814013(KCNMA1)
GFR: 102039116(KCNMA1)
FAB: 101808418(KCNMA1)
PHI: 102099683(KCNMA1)
PMAJ: 107199677(KCNMA1)
CCAE: 111931041(KCNMA1)
CCW: 104697623(KCNMA1)
ETL: 114055902
FPG: 101915596(KCNMA1)
FCH: 102050777(KCNMA1)
CLV: 102089237(KCNMA1)
EGZ: 104129096(KCNMA1)
NNI: 104015238(KCNMA1)
ACUN: 113481413(KCNMA1)
PADL: 103920867(KCNMA1)
AAM: 106498905(KCNMA1)
ASN: 102383994(KCNMA1)
AMJ: 106736888(KCNMA1)
PSS: 102443545(KCNMA1)
CMY: 102943582(KCNMA1)
CPIC: 101935665
ACS: 100553783(kcnma1)
PVT: 110080331(KCNMA1)
PBI: 103067321(KCNMA1)
PMUR: 107294560
TSR: 106543426
GJA: 107114736(KCNMA1)
XLA: 108703370 373712(kcnma1.L)
XTR: 100491898(kcnma1)
NPR: 108788403(KCNMA1)
DRE: 568554(kcnma1a) 798583(kcnma1b)
TRU: 101064381 101078302(kcnma1)
ONL: 100692364(kcnma1) 100703246
OLA: 101155390(kcnma1) 101174692
PRET: 103476821 103481816(kcnma1)
NFU: 107376042 107387848(kcnma1)
ALIM: 106515337(kcnma1) 106517014
AOCE: 111574789 111587260(kcnma1)
CSEM: 103381911(kcnma1) 103386992
HCQ: 109512391(kcnma1)
SFM: 108920903 108939557(kcnma1)
LCM: 102354999(KCNMA1)
CMK: 103181796(kcnma1)
RTP: 109914705
BFO: 118411517
CIN: 100179948
SPU: 578468
SKO: 100375734
DME: Dmel_CG10693(slo)
DER: 6554692
DSE: 6607786
DSI: Dsimw501_GD21120(Dsim_GD21120)
DAN: 6500007
DSR: 110189081
DPE: 6594809
DMN: 108156627
DWI: 6648174
DMO: Dmoj_GI24019(Dmoj_slo)
DAZ: 108616926
DNV: 108653665
DHE: 111593694
DVI: 6630600
MDE: 101896394
LCQ: 111676474
AAG: 5578934
AALB: 109398458
AME: 413994
BIM: 100749230
BTER: 100650043
CCAL: 108626476
OBB: 114876601
SOC: 105193937
AEC: 105150427
ACEP: 105627667
PBAR: 105428793
VEM: 105567794
HST: 105181681
DQU: 106751765
CFO: 105258647
LHU: 105677167
PGC: 109859852
OBO: 105279361
PCF: 106787588
NVI: 100122182(Slo)
CSOL: 105361736
MDL: 103575149
TCA: 657078
ATD: 109595401
NVL: 108569422
BMOR: 101738409
BMAN: 114245213
PMAC: 106717894
PRAP: 110995314
HAW: 110383928
TNL: 113500419
PXY: 105388890
API: 100169520
DNX: 107162111
AGS: 114119641
RMD: 113551121
BTAB: 109031079
CLEC: 106664000
ZNE: 110830367
FCD: 110844267
TUT: 107364487
CEL: CELE_Y51A2D.19(slo-1)
CBR: CBG12923(Cbr-slo-1)
PCAN: 112576630
CRG: 105338529
MYI: 110467332
OBI: 106878324
LAK: 106176102
NVE: 116602053
EPA: 110241467
ADF: 107349018
AMIL: 114969721
PDAM: 113671373
SPIS: 111336401
DGT: 114527553
AQU: 105314193
DDI: DDB_G0269896(kcnma1)
DFA: DFA_05869(kcnma1)
SMIN: v1.2.029291.t1(symbB.v1.2.029291.t1)
SPAR: SPRG_03227
 » show all
Reference
  Authors
Wang YW, Ding JP, Xia XM, Lingle CJ
  Title
Consequences of the stoichiometry of Slo1 alpha and auxiliary beta subunits on functional properties of large-conductance Ca2+-activated K+ channels.
  Journal
J Neurosci 22:1550-61 (2002)
DOI:10.1523/JNEUROSCI.22-05-01550.2002
  Sequence
[hsa:3778]

KEGG   ORTHOLOGY: K05274
Entry
K05274                      KO                                     

Name
KCNMA3, KCNU1, KCA5.1
Definition
potassium large conductance calcium-activated channel subfamily M alpha member 3
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K05274  KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
Other DBs
GO: 0015269
TC: 1.A.1.3.5
Genes
HSA: 157855(KCNU1)
PTR: 464107(KCNU1)
PPS: 100967649(KCNU1)
GGO: 101141170(KCNU1)
PON: 100449161(KCNU1)
NLE: 100593921(KCNU1)
MCC: 697748(KCNU1)
MCF: 101925188(KCNU1)
CSAB: 103215616(KCNU1)
RRO: 104668008(KCNU1)
RBB: 108513588(KCNU1)
CJC: 100394787(KCNU1)
SBQ: 101040619(KCNU1)
MMU: 16532(Kcnu1)
MCAL: 110300172(Kcnu1)
MPAH: 110337075(Kcnu1)
RNO: 680912(Kcnu1)
MUN: 110566309(Kcnu1)
CGE: 100752893(Kcnu1)
HGL: 101722235(Kcnu1)
CCAN: 109701770(Kcnu1)
OCU: 103346203(KCNU1)
TUP: 102493286(KCNU1)
CFA: 482856(KCNU1)
VVP: 112916309(KCNU1)
AML: 100471509(KCNU1)
UMR: 103659141(KCNU1)
UAH: 113261999(KCNU1)
ORO: 101373053
ELK: 111144610
FCA: 101100716(KCNU1)
PTG: 102953950(KCNU1)
PPAD: 109262331(KCNU1)
AJU: 106978391(KCNU1)
BTA: 524144(KCNU1)
BOM: 102279494(KCNU1)
BIU: 109553264(KCNU1)
BBUB: 102404344(KCNU1)
CHX: 102184875(KCNU1)
OAS: 101110209(KCNU1)
SSC: 100521933(KCNU1)
CFR: 102521656(KCNU1)
BACU: 103020835(KCNU1)
LVE: 103076674(KCNU1)
OOR: 101282534(KCNU1)
DLE: 111173499(KCNU1)
PCAD: 102987851(KCNU1)
ECB: 100060065(KCNU1)
EAI: 106837690(KCNU1)
MYB: 102248062(KCNU1)
MYD: 102760651(KCNU1)
HAI: 109393575(KCNU1)
DRO: 112306690(KCNU1)
PALE: 102880950(KCNU1)
RAY: 107515946(KCNU1)
MJV: 108384747(KCNU1)
LAV: 100675383(KCNU1)
MDO: 103104104(KCNU1)
SHR: 100915819(KCNU1)
OAA: 100082109(KCNU1)
GGA: 100857499(KCNU1)
MGP: 100545347(KCNU1)
CJO: 107323792(KCNU1)
NMEL: 110387063(KCNU1)
APLA: 101789865
ACYG: 106044417(KCNU1)
FPG: 106112245(KCNU1)
EGZ: 104127837(KCNU1)
NNI: 104016049(KCNU1)
ACUN: 113488045(KCNU1)
PADL: 103912377(KCNU1)
AAM: 106498824(KCNU1)
ASN: 102375383
AMJ: 102564541(KCNU1)
PSS: 102462777(KCNU1)
CMY: 102931886(KCNU1)
CPIC: 101945702(KCNU1)
PVT: 110075168(KCNU1)
PBI: 103062776(KCNU1)
PMUR: 107290830(KCNU1)
PMUA: 114585872(KCNU1)
GJA: 107116643
 » show all
Reference
  Authors
Zhang X, Zeng X, Lingle CJ
  Title
Slo3 K+ channels: voltage and pH dependence of macroscopic currents.
  Journal
J Gen Physiol 128:317-36 (2006)
DOI:10.1085/jgp.200609552
  Sequence
[mmu:16532]

KEGG   ORTHOLOGY: K04937
Entry
K04937                      KO                                     

Name
KCNMB1
Definition
potassium large conductance calcium-activated channel subfamily M beta member 1
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
Other DBs
GO: 0015269
TC: 8.A.14.1.2
Genes
HSA: 3779(KCNMB1)
PTR: 462258(KCNMB1)
PPS: 100977305(KCNMB1)
GGO: 101138700(KCNMB1)
PON: 100454172(KCNMB1)
NLE: 100604672(KCNMB1)
MCC: 700624(KCNMB1)
MCF: 102135837(KCNMB1)
CSAB: 103244960(KCNMB1)
RRO: 104663600(KCNMB1)
RBB: 108513608(KCNMB1)
CJC: 100395410(KCNMB1)
SBQ: 101049507(KCNMB1)
MMU: 16533(Kcnmb1)
MCAL: 110304397(Kcnmb1)
MPAH: 110331087(Kcnmb1)
RNO: 29747(Kcnmb1)
MUN: 110545308(Kcnmb1)
CGE: 100765448(Kcnmb1)
NGI: 103748177(Kcnmb1)
HGL: 101704020(Kcnmb1)
CCAN: 109686847(Kcnmb1)
OCU: 100009034(KCNMB1)
TUP: 102498192(KCNMB1)
CFA: 403983(KCNMB1)
VVP: 112926284(KCNMB1)
AML: 100463582(KCNMB1)
UMR: 103664498(KCNMB1)
UAH: 113264081(KCNMB1)
ORO: 101381979(KCNMB1)
ELK: 111140972
FCA: 101096637(KCNMB1)
PTG: 102950548(KCNMB1)
PPAD: 109267483(KCNMB1)
AJU: 106973444(KCNMB1)
BTA: 407176(KCNMB1)
BOM: 102286414(KCNMB1)
BIU: 109575011(KCNMB1)
BBUB: 102392300(KCNMB1)
CHX: 102185781(KCNMB1)
OAS: 100302624(KCNMB1)
SSC: 100271876(KCNMB1)
CFR: 102505725(KCNMB1)
CDK: 105089383(KCNMB1)
BACU: 103009178(KCNMB1)
LVE: 103081173(KCNMB1)
OOR: 101275005(KCNMB1)
DLE: 111185486(KCNMB1)
PCAD: 102990251(KCNMB1)
ECB: 100059234(KCNMB1)
EPZ: 103540740(KCNMB1)
EAI: 106837364(KCNMB1)
MYB: 102244181(KCNMB1)
MYD: 102775346(KCNMB1)
MNA: 107540345(KCNMB1)
HAI: 109379362(KCNMB1)
DRO: 112319583(KCNMB1)
PALE: 102892566(KCNMB1)
RAY: 107518473(KCNMB1)
MJV: 108393846(KCNMB1)
LAV: 100663278(KCNMB1)
TMU: 101357018
MDO: 100030975(KCNMB1)
SHR: 100920082(KCNMB1)
PCW: 110212313(KCNMB1)
OAA: 100077694(KCNMB1)
GGA: 395301(KCNMB1)
MGP: 100538592(KCNMB1)
CJO: 107320446(KCNMB1)
NMEL: 110405121(KCNMB1)
APLA: 101800584(KCNMB1)
ACYG: 106034329(KCNMB1)
TGU: 100218704
LSR: 110475698
SCAN: 103823773
GFR: 102044706(KCNMB1)
FAB: 101814109
PHI: 102102402(KCNMB1)
PMAJ: 107198549(KCNMB1)
CCAE: 111935675(KCNMB1)
CCW: 104696037(KCNMB1)
ETL: 114068942
FPG: 101915137(KCNMB1)
FCH: 102056620(KCNMB1)
CLV: 102086473(KCNMB1)
EGZ: 104135844(KCNMB1)
NNI: 104016554(KCNMB1)
ACUN: 113485217(KCNMB1)
PADL: 103921965(KCNMB1)
AAM: 106486092
ASN: 102380947
AMJ: 102573672(KCNMB1)
PSS: 102459137(KCNMB1)
CMY: 102930973
CPIC: 101946273(KCNMB1)
ACS: 103277859(kcnmb1)
PVT: 110072289(KCNMB1)
PBI: 103060291
PMUR: 107285401
TSR: 106557349
PMUA: 114590908(KCNMB1)
GJA: 107114865
XLA: 101027279
XTR: 100498003(kcnmb1)
NPR: 108795125(KCNMB1)
 » show all
Reference
PMID:8799178
  Authors
Tseng-Crank J, Godinot N, Johansen TE, Ahring PK, Strobaek D, Mertz R, Foster CD, Olesen SP, Reinhart PH
  Title
Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.
  Journal
Proc Natl Acad Sci U S A 93:9200-5 (1996)
DOI:10.1073/pnas.93.17.9200
  Sequence
[hsa:3779]

KEGG   ORTHOLOGY: K04938
Entry
K04938                      KO                                     

Name
KCNMB2
Definition
potassium large conductance calcium-activated channel subfamily M beta member 2
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
Other DBs
GO: 0015269
TC: 8.A.14.1.3
Genes
HSA: 10242(KCNMB2)
PTR: 460857(KCNMB2)
PPS: 100993924(KCNMB2)
GGO: 101142833(KCNMB2)
PON: 100451311(KCNMB2)
NLE: 100584771(KCNMB2)
MCC: 710221(KCNMB2)
MCF: 102119929(KCNMB2)
CSAB: 103221216(KCNMB2)
RRO: 104670662(KCNMB2)
RBB: 108532735(KCNMB2)
CJC: 100394193(KCNMB2)
SBQ: 101028055(KCNMB2)
MMU: 72413(Kcnmb2)
MCAL: 110291605(Kcnmb2)
MPAH: 110320535(Kcnmb2)
RNO: 294961(Kcnmb2)
MUN: 110556262(Kcnmb2)
CGE: 100761612(Kcnmb2)
NGI: 103738599(Kcnmb2)
HGL: 101709984(Kcnmb2)
CCAN: 109676836(Kcnmb2)
OCU: 100344926(KCNMB2)
TUP: 102482468(KCNMB2)
CFA: 488179(KCNMB2)
VVP: 112910473(KCNMB2)
AML: 100483809(KCNMB2)
UMR: 103676128(KCNMB2)
UAH: 113254860(KCNMB2)
ORO: 101371468(KCNMB2)
ELK: 111152292
FCA: 101097911(KCNMB2)
PTG: 102965846(KCNMB2)
PPAD: 109275157(KCNMB2)
AJU: 106973878(KCNMB2)
BTA: 534568(KCNMB2)
BOM: 102273395(KCNMB2)
BIU: 109557918(KCNMB2)
BBUB: 102403224(KCNMB2)
CHX: 102169423(KCNMB2)
OAS: 100620053(KCNMB2)
SSC: 100271877(KCNMB2)
CFR: 102524183(KCNMB2)
CDK: 105085931(KCNMB2)
BACU: 103017942
LVE: 103083839(KCNMB2)
OOR: 101278969(KCNMB2)
DLE: 111173875(KCNMB2)
PCAD: 102987282(KCNMB2)
ECB: 100058055(KCNMB2)
EPZ: 103552562(KCNMB2)
EAI: 106829319(KCNMB2)
MYB: 102240811(KCNMB2)
MYD: 102759976(KCNMB2)
MNA: 107541098(KCNMB2)
HAI: 109372680(KCNMB2)
DRO: 112304981(KCNMB2)
PALE: 102888572(KCNMB2)
RAY: 107517571(KCNMB2)
MJV: 108406972(KCNMB2)
LAV: 100658510(KCNMB2)
TMU: 101347532
MDO: 100010318(KCNMB2)
SHR: 100931574(KCNMB2)
PCW: 110204386(KCNMB2)
OAA: 100074073(KCNMB2)
GGA: 770907(KCNMB2)
MGP: 100547178(KCNMB2)
CJO: 107318146(KCNMB2)
NMEL: 110398166
APLA: 101796828
ACYG: 106032022
TGU: 100226973(KCNMB2)
LSR: 110478029
SCAN: 103815302
GFR: 102036926(KCNMB2)
FAB: 101816257(KCNMB2)
PHI: 102099632(KCNMB2)
PMAJ: 107209011(KCNMB2)
CCAE: 111933348
CCW: 104688023
ETL: 114062413
FPG: 101910854(KCNMB2)
FCH: 102048606
CLV: 102083677
EGZ: 104129989
NNI: 104019597
ACUN: 113483594
PADL: 103914964
AAM: 106482246(KCNMB2)
ASN: 102388410(KCNMB2)
AMJ: 102572400(KCNMB2)
PSS: 102449274(KCNMB2)
CMY: 102930415(KCNMB2)
CPIC: 101933933(KCNMB2)
ACS: 100564707(kcnmb2)
PVT: 110081907(KCNMB2)
PBI: 103050687(KCNMB2)
PMUR: 107285702(KCNMB2)
TSR: 106556269(KCNMB2)
PMUA: 114598000(KCNMB2) 114598151
GJA: 107110961(KCNMB2)
XLA: 108710911(kcnmb1.L) 108713284(kcnmb1.S) 108717003 108718093(kcnmb2.S)
XTR: 100493738(kcnmb2)
NPR: 108785758(KCNMB2)
DRE: 541398(kcnmb2) 796753(si:ch211-247n2.1)
IPU: 108271293(kcnmb2)
PHYP: 113533705(kcnmb2) 113540640
EEE: 113568880(kcnmb2)
TRU: 101075109(kcnmb2)
LCO: 104931137
NCC: 104963677 104967190(kcnmb2)
XMA: 102237825(kcnmb2)
XCO: 114151587(kcnmb2)
PRET: 103464019(kcnmb2) 103479070
CVG: 107082617 107091706(kcnmb2)
KMR: 108238227(kcnmb2)
ALIM: 106530183(kcnmb2)
HCQ: 109520498(kcnmb2)
ELS: 105025896(kcnmb2) 105028917
SFM: 108921545 108937310(kcnmb2)
PKI: 111853556 111860538(kcnmb2)
LCM: 102348312(KCNMB2) 102349471(KCNMB1)
CMK: 103175778(kcnmb2)
RTP: 109925590(kcnmb2)
CIN: 100178422
EPA: 110235285
SPIS: 111330001
 » show all
Reference
  Authors
Wallner M, Meera P, Toro L
  Title
Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog.
  Journal
Proc Natl Acad Sci U S A 96:4137-42 (1999)
DOI:10.1073/pnas.96.7.4137
  Sequence
[hsa:10242]

KEGG   ORTHOLOGY: K04939
Entry
K04939                      KO                                     

Name
KCNMB3
Definition
potassium large conductance calcium-activated channel subfamily M beta member 3
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
Other DBs
GO: 0015269
TC: 8.A.14.1.4
Genes
HSA: 27094(KCNMB3)
PTR: 744497 745901(KCNMB3)
PPS: 103782693(KCNMB3)
GGO: 101144185(KCNMB3)
PON: 100453047(KCNMB3)
NLE: 105740549(KCNMB3)
MCC: 709856(KCNMB3)
MCF: 102121578(KCNMB3)
CSAB: 103221213(KCNMB3)
RRO: 104670628(KCNMB3)
RBB: 108532951(KCNMB3)
CJC: 100403137(KCNMB3)
SBQ: 101033580
MMU: 100502876(Kcnmb3)
MCAL: 110291997(Kcnmb3)
MPAH: 110321004(Kcnmb3)
RNO: 310303(Kcnmb3)
MUN: 110556254(Kcnmb3)
CGE: 100758210(Kcnmb3)
NGI: 103738595(Kcnmb3)
HGL: 101712289(Kcnmb3)
CCAN: 109689671(Kcnmb3)
OCU: 100345697(KCNMB3)
TUP: 102488635(KCNMB3)
CFA: 488085(KCNMB3)
VVP: 112926218(KCNMB3)
AML: 100484063(KCNMB3)
UMR: 103676126(KCNMB3)
UAH: 113254812(KCNMB3)
ELK: 111147553
FCA: 101097167(KCNMB3)
PTG: 102964769(KCNMB3)
PPAD: 109275160(KCNMB3)
AJU: 106973881(KCNMB3)
BTA: 539609(KCNMB3)
BOM: 102284773(KCNMB3)
BIU: 109557867(KCNMB3)
BBUB: 102401064(KCNMB3)
CHX: 102168667(KCNMB3)
OAS: 101109757(KCNMB3)
SSC: 100271878(KCNMB3)
CFR: 102523247(KCNMB3)
CDK: 105085927(KCNMB3)
BACU: 103014279(KCNMB3)
OOR: 101272255(KCNMB3)
PCAD: 102987234(KCNMB3)
ECB: 100065646(KCNMB3)
EPZ: 103552224(KCNMB3)
EAI: 106829315(KCNMB3)
MYB: 102239366(KCNMB3)
MYD: 102758681(KCNMB3)
MNA: 107541085(KCNMB3)
HAI: 109372684(KCNMB3)
DRO: 112307674(KCNMB3)
PALE: 102889477(KCNMB3)
RAY: 107518045(KCNMB3)
MJV: 108406545(KCNMB3)
LAV: 100657662(KCNMB3)
TMU: 101346596
MDO: 100013118(KCNMB3)
SHR: 100933996(KCNMB3)
PCW: 110204493(KCNMB3)
OAA: 100073915(KCNMB3)
XLA: 100381136(kcnmb3.S) 108716204
XTR: 100493910(kcnmb3)
NPR: 108785757(KCNMB3)
DRE: 101885585(si:ch211-38m6.7)
SRX: 107708981
SANH: 107681773
SGH: 107599858
IPU: 108267996
PHYP: 113540045
AMEX: 103021527
EEE: 113570074
TRU: 101075334
NCC: 104967188
MZE: 101473677
ONL: 102081817
OLA: 101165505
XMA: 102235219
XCO: 114146905
PRET: 103479064
CVG: 107082600
NFU: 107384486
KMR: 108238244
ALIM: 106530182
AOCE: 111581475
CSEM: 103396159
LCF: 108883765
SDU: 111228906
SLAL: 111661241
HCQ: 109520497
BPEC: 110173400
MALB: 109974068
SASA: 106568783
OTW: 112259572
SALP: 111956956
ELS: 105028934
SFM: 108921678
PKI: 111853567
LCM: 102347605(KCNMB3)
CIN: 100186504
 » show all
Reference
  Authors
Xia XM, Ding JP, Zeng XH, Duan KL, Lingle CJ
  Title
Rectification and rapid activation at low Ca2+ of Ca2+-activated, voltage-dependent BK currents: consequences of rapid inactivation by a novel beta subunit.
  Journal
J Neurosci 20:4890-903 (2000)
DOI:10.1523/JNEUROSCI.20-13-04890.2000
  Sequence
[hsa:27094]

KEGG   ORTHOLOGY: K04941
Entry
K04941                      KO                                     

Name
KCNMB4
Definition
potassium large conductance calcium-activated channel subfamily M beta member 4
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04911  Insulin secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
Other DBs
GO: 0015269
TC: 8.A.14.1.1
Genes
HSA: 27345(KCNMB4)
PTR: 742962(KCNMB4)
PPS: 100975379(KCNMB4)
GGO: 101137669(KCNMB4)
PON: 100454228(KCNMB4)
NLE: 100582120(KCNMB4)
MCC: 717360(KCNMB4)
MCF: 102115600(KCNMB4)
CSAB: 103238713(KCNMB4)
RRO: 104658650(KCNMB4)
RBB: 108524796(KCNMB4)
CJC: 100413100(KCNMB4)
SBQ: 101046411(KCNMB4)
MMU: 58802(Kcnmb4)
MCAL: 110303525(Kcnmb4)
MPAH: 110326767(Kcnmb4)
RNO: 66016(Kcnmb4)
MUN: 110560326(Kcnmb4)
CGE: 100754855(Kcnmb4)
NGI: 103731661(Kcnmb4)
HGL: 101721804(Kcnmb4)
OCU: 100342622(KCNMB4)
TUP: 102473087(KCNMB4)
VVP: 112922273(KCNMB4)
AML: 100463833(KCNMB4)
UMR: 103656975(KCNMB4)
UAH: 113256276(KCNMB4)
ORO: 101365723(KCNMB4)
ELK: 111142114
FCA: 101101646(KCNMB4)
PTG: 102955896(KCNMB4)
PPAD: 109270503(KCNMB4)
AJU: 106967409(KCNMB4)
BTA: 520448(KCNMB4)
BOM: 102288138(KCNMB4)
BIU: 109559224(KCNMB4)
BBUB: 102413905(KCNMB4)
CHX: 102184787(KCNMB4)
OAS: 100620050(KCNMB4)
SSC: 100154587(KCNMB4)
CFR: 102520094(KCNMB4)
CDK: 105094388(KCNMB4)
BACU: 103010851(KCNMB4)
LVE: 103077658(KCNMB4)
OOR: 101289353(KCNMB4)
DLE: 111173746(KCNMB4)
PCAD: 102986340(KCNMB4)
ECB: 100063351(KCNMB4)
EPZ: 103557406(KCNMB4)
MYB: 102254182(KCNMB4)
MYD: 102761412(KCNMB4)
MNA: 107526648(KCNMB4)
HAI: 109387674(KCNMB4)
DRO: 112319148(KCNMB4)
PALE: 102887713(KCNMB4)
RAY: 107514514(KCNMB4)
MJV: 108402184(KCNMB4)
LAV: 100668504(KCNMB4)
TMU: 101352404
MDO: 100011529(KCNMB4)
SHR: 100921179(KCNMB4)
PCW: 110211063(KCNMB4)
OAA: 100079405(KCNMB4)
GGA: 417852(KCNMB4)
MGP: 100548575(KCNMB4)
CJO: 107310398(KCNMB4)
NMEL: 110392807(KCNMB4)
APLA: 113843426(KCNMB4)
ACYG: 106045389(KCNMB4)
TGU: 100232406(KCNMB4)
LSR: 110469836(KCNMB4)
SCAN: 103813674(KCNMB4)
GFR: 102037036(KCNMB4)
FAB: 101815253(KCNMB4)
PMAJ: 107204131(KCNMB4)
ETL: 114062156(KCNMB4)
FCH: 114017315(KCNMB4)
CLV: 102098291(KCNMB4)
EGZ: 104132951(KCNMB4)
NNI: 104011042(KCNMB4)
ACUN: 113491193(KCNMB4)
PADL: 103920035(KCNMB4)
ASN: 102379441(KCNMB4)
AMJ: 102567213(KCNMB4)
PSS: 102460024(KCNMB4)
CMY: 102931735(KCNMB4)
CPIC: 101944669(KCNMB4)
ACS: 100557510(kcnmb4)
PVT: 110075133(KCNMB4)
PBI: 103060434(KCNMB4)
PMUR: 107283844(KCNMB4)
TSR: 106552434(KCNMB4)
PMUA: 114605479(KCNMB4)
GJA: 107105718(KCNMB4)
XLA: 108711099(kcnmb4.L) 108712485(kcnmb4.S)
XTR: 549965(kcnmb4)
NPR: 108804555(KCNMB4)
IPU: 108280091(kcnmb4)
PHYP: 113531812(kcnmb4)
EEE: 113575784(kcnmb4)
TRU: 101069933(kcnmb4)
NCC: 104953139(kcnmb4)
MZE: 101473284(kcnmb4)
ONL: 100691688(kcnmb4)
OLA: 101171123(kcnmb4)
XMA: 102232146(kcnmb4)
XCO: 114140926(kcnmb4)
PRET: 103459347(kcnmb4)
CVG: 107089070(kcnmb4)
NFU: 107387671(kcnmb4)
KMR: 108249716
ALIM: 106536713
AOCE: 111563456(kcnmb4)
CSEM: 103383091(kcnmb4)
LCF: 108901354(kcnmb4)
SDU: 111225007(kcnmb4)
SLAL: 111651034
MALB: 109967705(kcnmb4)
SASA: 106576474(kcnmb4)
OTW: 112240826(kcnmb4) 112241739
ELS: 109616881(kcnmb4)
SFM: 108936445(kcnmb4) 108942218
PKI: 111851175(kcnmb4) 111858642
LCM: 102349165(KCNMB4)
CMK: 103185321(kcnmb4)
RTP: 109938246(kcnmb4)
LAK: 106154597
 » show all
Reference
  Authors
Brenner R, Jegla TJ, Wickenden A, Liu Y, Aldrich RW
  Title
Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.
  Journal
J Biol Chem 275:6453-61 (2000)
DOI:10.1074/jbc.275.9.6453
  Sequence
[hsa:27345]

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