KEGG ORTHOLOGY: K05036

ORTHOLOGY: K05036

Entry

K05036                      KO

Symbol

SLC6A3, DAT

Name

solute carrier family 6 (neurotransmitter transporter, dopamine) member 3

Pathway

map04721

Synaptic vesicle cycle

map04728

Dopaminergic synapse

map05012

Parkinson disease

map05022

Pathways of neurodegeneration - multiple diseases

map05030

Cocaine addiction

map05031

Amphetamine addiction

map05034

Alcoholism

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   04721 Synaptic vesicle cycle
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05022 Pathways of neurodegeneration - multiple diseases
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
  09165 Substance dependence
   05030 Cocaine addiction
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05031 Amphetamine addiction
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05034 Alcoholism
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
   K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3

Other DBs

GO:

0005330

TC:	2.A.22.1.3

Genes

HSA:	6531(SLC6A3)

PTR:	750842(SLC6A3)

PPS:	100991516(SLC6A3)

PON:	100435121(SLC6A3)

NLE:	100596846(SLC6A3)

HMH:	116456672(SLC6A3)

MCC:	574143(SLC6A3)

MCF:	102142756(SLC6A3)

MTHB:

126957406

MNI:	105464564(SLC6A3)

CSAB:

103214932(SLC6A3)

CATY:

105600707(SLC6A3)

PANU:

101022805(SLC6A3)

TGE:	112625992(SLC6A3)

MLEU:

105528127(SLC6A3)

RRO:	104668699(SLC6A3)

RBB:	108513703(SLC6A3)

TFN:	117064705(SLC6A3)

PTEH:

111528338(SLC6A3)

CANG:

105519692(SLC6A3)

CJC:	100393968(SLC6A3)

SBQ:	101032424(SLC6A3)

CIMI:

108294173(SLC6A3)

CSYR:

103271220(SLC6A3)

MMUR:

105876449(SLC6A3)

LCAT:

123648018(SLC6A3)

PCOQ:

105825819(SLC6A3)

OGA:	100965905(SLC6A3)

MMU:	13162(Slc6a3)

MCAL:

110307893(Slc6a3)

MPAH:

110328936(Slc6a3)

RNO:	24898(Slc6a3)

MCOC:

116083177(Slc6a3)

ANU:	117723935(Slc6a3)

MUN:	110545376(Slc6a3)

CGE:

100774258

MAUA:

110343686(Slc6a3)

PROB:

127220860(Slc6a3)

PLEU:

114696105(Slc6a3)

MORG:

121433667(Slc6a3)

MFOT:

126503802

AAMP:

119810258(Slc6a3)

NGI:	103749676(Slc6a3)

HGL:	101709245(Slc6a3)

CPOC:

100714898(Slc6a3)

CCAN:

109698262(Slc6a3)

DORD:

105983816(Slc6a3)

DSP:	122120948(Slc6a3)

PLOP:

125367624(Slc6a3)

NCAR:

124987217

OPI:	101536711(SLC6A3)

TUP:	102500212(SLC6A3)

GVR:	103606824(SLC6A3)

CFA:	609304(SLC6A3)

CLUD:

112662644(SLC6A3)

VVP:	112935444(SLC6A3)

VLG:	121477472(SLC6A3)

NPO:	129498894(SLC6A3)

AML:	100478402(SLC6A3)

UMR:	103679238(SLC6A3)

UAH:	113260791(SLC6A3)

UAR:	123799122(SLC6A3)

ELK:

111153448

LLV:

125100023

MPUF:

101689277(SLC6A3)

NVS:	122902425(SLC6A3)

ORO:	101362179(SLC6A3)

EJU:	114198569(SLC6A3)

ZCA:	113929486(SLC6A3)

MLX:	118006229(SLC6A3)

NSU:	110577687(SLC6A3)

LWW:	102748609(SLC6A3)

FCA:	101101618(SLC6A3)

PBG:	122480191(SLC6A3)

LRUF:

124510500

PTG:	102971363(SLC6A3)

PPAD:

109267683(SLC6A3)

PUC:

125934743

AJU:

106985115

HHV:	120235641(SLC6A3)

BTA:	788410(SLC6A3)

BOM:	102268138(SLC6A3)

BIU:	109574743(SLC6A3)

BBUB:

102401631(SLC6A3)

BBIS:

105001019(SLC6A3)

CHX:	102187167(SLC6A3)

OAS:	101111908(SLC6A3)

BTAX:

128066092(SLC6A3)

ODA:	120879278(SLC6A3)

CCAD:

122454559(SLC6A3)

SSC:	100521346(SLC6A3)

CFR:	102510470(SLC6A3)

CBAI:

105081248(SLC6A3)

CDK:	105102174(SLC6A3)

VPC:	102539205(SLC6A3)

BACU:

103002528(SLC6A3)

LVE:	103087626(SLC6A3)

OOR:	101289168(SLC6A3)

DLE:	111178539(SLC6A3)

PCAD:

102981726(SLC6A3)

PSIU:

116752055(SLC6A3)

NASI:

112390883(SLC6A3)

ECB:	100054747(SLC6A3)

EPZ:	103567498(SLC6A3)

EAI:	106835898(SLC6A3)

MYB:	102244563(SLC6A3)

MYD:	102770667(SLC6A3)

MMYO:

118657033(SLC6A3)

MLF:	102424965(SLC6A3)

MNA:	107536458(SLC6A3)

PKL:	118703499(SLC6A3)

HAI:	109371679(SLC6A3)

DRO:	112320941(SLC6A3)

SHON:

118998658(SLC6A3)

AJM:	119043343(SLC6A3)

PDIC:

114505082(SLC6A3)

PHAS:

123824758(SLC6A3)

MMF:	118641782(SLC6A3)

RFQ:	117024975(SLC6A3)

PALE:

102895017(SLC6A3)

PGIG:

120586141(SLC6A3)

PVP:	105301307(SLC6A3)

RAY:	107499955(SLC6A3)

MJV:	108400617(SLC6A3)

TOD:	119260671(SLC6A3)

SARA:

101548982(SLC6A3)

LAV:	100675742(SLC6A3)

TMU:

101341243

ETF:	101660195(SLC6A3)

MDO:	100015498(SLC6A3)

GAS:	123231574(SLC6A3)

SHR:	100914957(SLC6A3)

AFZ:

127543592

PCW:	110201221(SLC6A3)

OAA:	100074809(SLC6A3)

XLA:	108720038(slc6a3.S)

XTR:	100488824(slc6a3)

NPR:	108802238(SLC6A3)

RTEM:

120940580(SLC6A3)

BBUF:

121002523(SLC6A3)

BGAR:

122939416(SLC6A3)

DRE:	80787(slc6a3)

SRX:

107758825

SANH:

107701804(slc6a3)

SGH:	107558633 107564665

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127177824(slc6a3)

PPRM:

120465478(slc6a3)

MAMB:

125243975(slc6a3)

CIDE:

127497960

MASI:

127452625 127454385

IPU:	108272311(slc6a3)

PHYP:

113533694(slc6a3)

SMEO:

124385325(slc6a3)

TFD:	113648304(slc6a3)

AMEX:

103026128(slc6a3)

CMAO:

118813836(slc6a3)

EEE:

113592231

CHAR:

105905497(slc6a3)

TRU:	101072244(slc6a3)

TNG:	GSTEN00013866G001

LCO:	104940426(slc6a3)

NCC:	104943319(slc6a3)

CGOB:

115021666(slc6a3)

ELY:	117265547(slc6a3)

EFO:	125893853(slc6a3)

PLEP:

121945820(slc6a3)

SLUC:

116049211(slc6a3)

ECRA:

117946100(slc6a3)

ESP:	116690847(slc6a3)

PFLV:

114557281(slc6a3)

GAT:	120810599(slc6a3)

PPUG:

119198149(slc6a3)

MSAM:

119897882(slc6a3)

SCHU:

122881557(slc6a3)

CUD:	121513842(slc6a3)

ALAT:

119005645(slc6a3)

MZE:	101475398(slc6a3)

ONL:	100706735(slc6a3)

OAU:	116329393(slc6a3)

OLA:	101158881(slc6a3)

OML:	112144056(slc6a3)

XMA:	102218251(slc6a3)

XCO:	114141853(slc6a3)

XHE:	116717885(slc6a3)

PRET:

103478700(slc6a3)

PFOR:

103143599(slc6a3)

PLAI:

106945236(slc6a3)

PMEI:

106907849(slc6a3)

GAF:	122831123(slc6a3)

CVG:	107102765(slc6a3)

CTUL:

119791322(slc6a3)

GMU:	124864227(slc6a3)

NFU:	107378744(slc6a3)

KMR:	108232182(slc6a3)

ALIM:

106521609

NWH:	119410352(slc6a3)

AOCE:

111566236(slc6a3)

MCEP:

125016506(slc6a3)

CSEM:

103388332(slc6a3)

POV:	109632076(slc6a3)

SSEN:

122775206(slc6a3)

HHIP:

117777284(slc6a3)

HSP:	118113106(slc6a3)

LCF:

108889083

SDU:	111227736(slc6a3)

SLAL:

111673067(slc6a3)

XGL:	120784168(slc6a3)

HCQ:	109521906(slc6a3)

SSCV:

125975124

BPEC:

110171536(slc6a3)

MALB:

109958350(slc6a3)

BSPL:

114842584(slc6a3)

STRU:

115190613 115191073(slc6a3)

OMY:	110511094(slc6a3)

OGO:

124025757

CCLU:

121542316 121559425

ELS:	105016608(slc6a3)

SFM:	108940585(slc6a3)

PKI:	111843531(slc6a3)

AANG:

118219797(slc6a3)

LOC:	102685205(slc6a3)

PSPA:

121308264 121314774

ARUT:

117394811 117400504

PSEX:

120515953(slc6a3)

LCM:	102364171(SLC6A3)

CMK:

103184821

RTP:

109935564

CPLA:

122549736

SPU:	115926893 584179

APLC:

110981970

AJC:

117109548

SKO:

100313588

DME:	Dmel_CG8380(DAT)

DER:

6548430

DSE:

6609460

DSI:	Dsimw501_GD25533(Dsim_GD25533)

DYA:	Dyak_GE14056

DAN:

DSR:

DPO:

DPE:

DMN:	108159069 117191542

DWI:

6640614

DGR:

6571527

DMO:	Dmoj_GI19005

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

RZE:	108361169 108366618

MDE:

SCAC:

LCQ:

LSQ:

HIS:

AGA:	AgaP_AGAP007367

ACOZ:

AARA:

AMER:

ASTE:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ010746

CPII:

120422641

CNS:

116352262

BCOO:

119080698

AME:	412285(Dat)

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

LHT:

MDL:

CGLO:

DAM:

AGIF:

CINS:

CCIN:

DSM:	124406193 124413674

NPT:	124213730 124222346

NFB:

124178536

NLO:	107226905 107227060

NVG:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:	111425481 111425995

BMOR:

101744281

BMAN:

114248855

MSEX:

115443108 115447274

DPL:	KGM_212172

BANY:

NIQ:

PMAC:

PPOT:

PXU:	106126168 106127228

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

CFEL:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:	103506499 103515758

CLEC:

106661545

HHAL:

106678308

NLU:

111053418

PHU:	Phum_PHUM097380

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

FCD:	110850919 110852168

DPX:	DAPPUDRAFT_60804

DMK:

116922827

DPZ:

124321010

PVM:

113806330

PJA:	122248067 122255136

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

ESN:	126999270 127010420

HAZT:

EAF:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DFR:

CSCU:

PTEP:

SDM:

LPOL:

PMEO:

CEL:	CELE_T23G5.5(dat-1)

CBR:	CBG_10151(Cbr-dat-1)

BMY:	BM_BM5960(Bma-dat-1)

LOA:	LOAG_07270

TSP:

Tsp_00144

HRO:	HELRODRAFT_74696

LGI:	LOTGIDRAFT_103896

PCAN:

112553260 112561268

BGT:

106074484

GAE:	121368532 121389464

HRF:	124124869 124131020 124131023 124131024 124138925 124142096 124148020

HRJ:	124253536 124255180 124259036 124259039 124262729 124264939 124270287 124280952 124290245

CRG:

MYI:

PMAX:

MCAF:

MMER:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_156320

OVI:	T265_12790

» show all

Reference

PMID:14531049

Authors

Uhl GR

Title

Dopamine transporter: basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism.

Journal

Mov Disord 18 Suppl 7:S71-80 (2003)
DOI:10.1002/mds.10578

Reference

PMID:1406597

Authors

Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG

Title

Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.

Journal

Mol Pharmacol 42:383-90 (1992)

Sequence

[hsa:6531]

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Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   TC (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Drug (45)   
   KEGG DRUG (45)   
Gene (841)   
   KEGG GENES (463)   
   KEGG MGENES (82)   
   RefGene (289)   
   OC (7)   
Literature (2)   
   PubMed (2)   
All databases (906)   

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