KEGG   ORTHOLOGY: K05130
Entry
K05130                      KO                                     

Name
IFNAR1
Definition
interferon receptor 1
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04151 PI3K-Akt signaling pathway
    K05130  IFNAR1; interferon receptor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05130  IFNAR1; interferon receptor 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05130  IFNAR1; interferon receptor 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04621 NOD-like receptor signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04650 Natural killer cell mediated cytotoxicity
    K05130  IFNAR1; interferon receptor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05130  IFNAR1; interferon receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05130  IFNAR1; interferon receptor 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K05130  IFNAR1; interferon receptor 1
   05160 Hepatitis C
    K05130  IFNAR1; interferon receptor 1
   05171 Coronavirus disease - COVID-19
    K05130  IFNAR1; interferon receptor 1
   05164 Influenza A
    K05130  IFNAR1; interferon receptor 1
   05162 Measles
    K05130  IFNAR1; interferon receptor 1
   05168 Herpes simplex virus 1 infection
    K05130  IFNAR1; interferon receptor 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05130  IFNAR1; interferon receptor 1
   05169 Epstein-Barr virus infection
    K05130  IFNAR1; interferon receptor 1
   05165 Human papillomavirus infection
    K05130  IFNAR1; interferon receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05130  IFNAR1; interferon receptor 1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05130  IFNAR1; interferon receptor 1
Other DBs
GO: 0004905
Genes
HSA: 3454(IFNAR1)
PTR: 458516(IFNAR1)
PPS: 100995446(IFNAR1)
GGO: 101141158(IFNAR1)
PON: 100443118(IFNAR1)
NLE: 100583382(IFNAR1)
MCC: 699604(IFNAR1)
MCF: 101926190(IFNAR1)
CSAB: 103216875(IFNAR1)
RRO: 104658750(IFNAR1)
RBB: 108536856(IFNAR1)
CJC: 100410306(IFNAR1)
SBQ: 101035044(IFNAR1)
MMU: 15975(Ifnar1)
MCAL: 110311756(Ifnar1)
MPAH: 110329827(Ifnar1)
RNO: 288264(Ifnar1)
MUN: 110541917(Ifnar1)
CGE: 100768581(Ifnar1)
NGI: 103736454
HGL: 101724158(Ifnar1)
CCAN: 109686809
OCU: 100338604(IFNAR1)
TUP: 102480854(IFNAR1)
CFA: 100856529(IFNAR1) 609830
VVP: 112909256(IFNAR1)
AML: 100481921(IFNAR1)
UMR: 103673220(IFNAR1)
UAH: 113264796(IFNAR1)
ORO: 101370046(IFNAR1)
ELK: 111155707
FCA: 101092535(IFNAR1)
PTG: 102955444(IFNAR1)
PPAD: 109249714(IFNAR1)
AJU: 106966457(IFNAR1)
BTA: 282257(IFNAR1)
BOM: 102275793(IFNAR1)
BIU: 109570535(IFNAR1)
BBUB: 102394317(IFNAR1)
CHX: 102191552(IFNAR1)
OAS: 443126(IFNAR1)
SSC: 396658(IFNAR1)
CFR: 102523764(IFNAR1)
CDK: 105089868(IFNAR1)
BACU: 102998082(IFNAR1)
LVE: 103068842(IFNAR1)
OOR: 101284215(IFNAR1)
DLE: 111163780(IFNAR1)
PCAD: 102991034(IFNAR1)
ECB: 100063402(IFNAR1)
EPZ: 103549120(IFNAR1)
EAI: 106832840(IFNAR1)
MYB: 102245971(IFNAR1)
MYD: 102772617(IFNAR1)
MNA: 107537477(IFNAR1)
HAI: 109373231(IFNAR1)
DRO: 112305552(IFNAR1)
PALE: 102892040(IFNAR1)
RAY: 107519592(IFNAR1)
MJV: 108396596(IFNAR1)
LAV: 100667586(IFNAR1)
TMU: 101361715
SHR: 100919064(IFNAR1)
PCW: 110214849
OAA: 100083477(IFNAR1)
GGA: 395665(IFNAR1)
MGP: 100542669(IFNAR1)
CJO: 107322958(IFNAR1)
NMEL: 110402456(IFNAR1)
APLA: 101790975(IFNAR1)
ACYG: 106043409(IFNAR1)
TGU: 115490564(IFNAR1)
LSR: 110474945(IFNAR1)
SCAN: 103824810(IFNAR1)
GFR: 102044653(IFNAR1)
FAB: 101814442(IFNAR1)
PHI: 102110908(IFNAR1)
PMAJ: 107198759(IFNAR1)
CCAE: 111928918
CCW: 104698093(IFNAR1)
ETL: 114071602(IFNAR1)
FPG: 101919760(IFNAR1)
FCH: 102054913(IFNAR1)
CLV: 102088758(IFNAR1)
EGZ: 104128164(IFNAR1)
NNI: 104020173(IFNAR1)
ACUN: 113479018(IFNAR1)
PADL: 103920316(IFNAR1)
AAM: 106494990(IFNAR1)
ASN: 102381089(IFNAR1)
AMJ: 102567201(IFNAR1)
PSS: 102462024(IFNAR1)
CMY: 102945791(IFNAR1)
CPIC: 101942233(IFNAR1)
ACS: 103281135(ifnar1)
PVT: 110080372(IFNAR1)
PBI: 103064969(IFNAR1)
PMUR: 107290638(IFNAR1)
PMUA: 114596050(IFNAR1)
GJA: 107121921
XTR: 100498552(ifnar1)
NPR: 108794147
SANH: 107700959
SGH: 107558503
TRU: 101071242
SFM: 108929004
PKI: 111834154
LCM: 102345381(IFNAR1)
 » show all
Reference
PMID:2153461
  Authors
Uze G, Lutfalla G, Gresser I
  Title
Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA.
  Journal
Cell 60:225-34 (1990)
DOI:10.1016/0092-8674(90)90738-Z
  Sequence
[hsa:3454]

KEGG   ORTHOLOGY: K05131
Entry
K05131                      KO                                     

Name
IFNAR2
Definition
interferon receptor 2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05160  Hepatitis C
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04151 PI3K-Akt signaling pathway
    K05131  IFNAR2; interferon receptor 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05131  IFNAR2; interferon receptor 2
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05131  IFNAR2; interferon receptor 2
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04621 NOD-like receptor signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04650 Natural killer cell mediated cytotoxicity
    K05131  IFNAR2; interferon receptor 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05131  IFNAR2; interferon receptor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05131  IFNAR2; interferon receptor 2
  09172 Infectious disease: viral
   05160 Hepatitis C
    K05131  IFNAR2; interferon receptor 2
   05171 Coronavirus disease - COVID-19
    K05131  IFNAR2; interferon receptor 2
   05164 Influenza A
    K05131  IFNAR2; interferon receptor 2
   05162 Measles
    K05131  IFNAR2; interferon receptor 2
   05168 Herpes simplex virus 1 infection
    K05131  IFNAR2; interferon receptor 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05131  IFNAR2; interferon receptor 2
   05169 Epstein-Barr virus infection
    K05131  IFNAR2; interferon receptor 2
   05165 Human papillomavirus infection
    K05131  IFNAR2; interferon receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05131  IFNAR2; interferon receptor 2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05131  IFNAR2; interferon receptor 2
Other DBs
GO: 0004905
Genes
HSA: 3455(IFNAR2)
PTR: 473965(IFNAR2)
PPS: 100995792(IFNAR2)
GGO: 101140784(IFNAR2)
PON: 100441293(IFNAR2)
NLE: 100599809(IFNAR2)
MCC: 699726(IFNAR2)
MCF: 102140083(IFNAR2)
CSAB: 103216889(IFNAR2)
RRO: 104658748(IFNAR2)
RBB: 108536852(IFNAR2)
MMU: 15976(Ifnar2)
MCAL: 110311924(Ifnar2)
MPAH: 110329735(Ifnar2)
RNO: 686326(Ifnar2)
MUN: 110541888(Ifnar2)
CGE: 100768006
NGI: 103736458(Ifnar2)
HGL: 101722391(Ifnar2)
CCAN: 109699947(Ifnar2)
OCU: 100338097(IFNAR2)
TUP: 102477904(IFNAR2)
CFA: 100856468(IFNAR2) 487737
VVP: 112909270(IFNAR2)
AML: 100482679(IFNAR2)
ORO: 101386107(IFNAR2)
ELK: 111155645
FCA: 101090285(IFNAR2)
PTG: 102954859(IFNAR2)
PPAD: 109249711(IFNAR2)
AJU: 106966459(IFNAR2)
BTA: 282258(IFNAR2)
BOM: 102275218(IFNAR2)
BIU: 109572614
BBUB: 102394946(IFNAR2)
CHX: 102175057(IFNAR2)
OAS: 443363(IFNAR2)
SSC: 100533555(IFNAR2)
CFR: 102518206(IFNAR2)
CDK: 105089871(IFNAR2)
BACU: 103020704(IFNAR2)
LVE: 103069127(IFNAR2)
OOR: 101283958(IFNAR2)
DLE: 111163874(IFNAR2)
PCAD: 102989482(IFNAR2)
ECB: 100052489(IFNAR2)
EPZ: 103549136(IFNAR2)
EAI: 106832843(IFNAR2)
MYB: 102259457(IFNAR2)
MYD: 102772901(IFNAR2)
HAI: 109373246(IFNAR2)
DRO: 112305536(IFNAR2)
PALE: 102891485(IFNAR2)
RAY: 107519578(IFNAR2)
MJV: 108409505(IFNAR2)
LAV: 100672898(IFNAR2)
TMU: 101354122
MDO: 103092556(IFNAR2)
SHR: 105750087(IFNAR2)
PCW: 110214853(IFNAR2)
OAA: 103170687(IFNAR2)
GGA: 395664(IFNAR2)
MGP: 100539587(IFNAR2)
CJO: 107322936(IFNAR2)
NMEL: 110402433(IFNAR2)
APLA: 101804315(IFNAR2)
ACYG: 106043436(IFNAR2)
TGU: 115497673(IFNAR2)
LSR: 110474946(IFNAR2)
SCAN: 103824806(IFNAR2)
GFR: 102042202(IFNAR2)
FAB: 101814062(IFNAR2)
PHI: 102101660(IFNAR2)
PMAJ: 107198545
CCAE: 111928947(IFNAR2)
CCW: 104698065
ETL: 114071273(IFNAR2)
FPG: 101919412(IFNAR2)
FCH: 102055258(IFNAR2)
CLV: 102097241(IFNAR2)
EGZ: 104128224(IFNAR2)
NNI: 104020172(IFNAR2)
ACUN: 113477658(IFNAR2)
PADL: 103920254(IFNAR2)
AAM: 106494988(IFNAR2)
ASN: 102381921(IFNAR2)
AMJ: 102566586(IFNAR2)
PSS: 102462520(IFNAR2)
CMY: 102945561(IFNAR2)
CPIC: 101941521(IFNAR2)
ACS: 103281133(ifnar2)
PVT: 110080371(IFNAR2)
PBI: 103063466(IFNAR2)
PMUR: 107290611(IFNAR2)
TSR: 106550452
GJA: 107110548(IFNAR2)
XTR: 100496877(ifnar2.2) 779845(ifnar2.1)
DRE: 777653(crfb2)
SRX: 107746586
SANH: 107653241
SGH: 107569726
CCAR: 109105674
IPU: 108266953
AMEX: 103046016
LCO: 104932498
XMA: 102219036
XCO: 114147537
PRET: 103461789
NFU: 107374287
KMR: 108251686
ALIM: 106530220
CSEM: 103392359
SDU: 111228083
SLAL: 111663409
HCQ: 109519251
BPEC: 110162048
MALB: 109951988
SALP: 111959819
ELS: 105031504
SFM: 108922254
PKI: 111860691
CMK: 103186765
RTP: 109928467
 » show all
Reference
PMID:8181059
  Authors
Novick D, Cohen B, Rubinstein M
  Title
The human interferon alpha/beta receptor: characterization and molecular cloning.
  Journal
Cell 77:391-400 (1994)
DOI:10.1016/0092-8674(94)90154-6
  Sequence
[hsa:3455]

KEGG   ORTHOLOGY: K05132
Entry
K05132                      KO                                     

Name
IFNGR1, CD119
Definition
interferon gamma receptor 1
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05164  Influenza A
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H00342  Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04066 HIF-1 signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04658 Th1 and Th2 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04659 Th17 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09172 Infectious disease: viral
   05164 Influenza A
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05168 Herpes simplex virus 1 infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05140 Leishmaniasis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05142 Chagas disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04090 CD molecules
    K05132  IFNGR1, CD119; interferon gamma receptor 1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05132  IFNGR1, CD119; interferon gamma receptor 1
CD molecules [BR:ko04090]
 Proteins
  K05132  CD119, IFNGR1; interferon gamma receptor 1
Other DBs
GO: 0004906
Genes
HSA: 3459(IFNGR1)
PTR: 747276(IFNGR1)
PPS: 100994342(IFNGR1)
GGO: 101150227(IFNGR1)
PON: 100171593(IFNGR1)
NLE: 100598615(IFNGR1)
MCC: 100423877(IFNGR1)
MCF: 101866179(IFNGR1)
CSAB: 103240303(IFNGR1)
RRO: 104675021(IFNGR1)
RBB: 108522967(IFNGR1)
CJC: 100386516(IFNGR1)
SBQ: 101054160(IFNGR1)
MMU: 15979(Ifngr1)
MCAL: 110303040(Ifngr1)
MPAH: 110338217(Ifngr1)
RNO: 116465(Ifngr1)
MUN: 110557641(Ifngr1)
CGE: 100772793(Ifngr1)
NGI: 103724895(Ifngr1)
HGL: 101709169(Ifngr1)
CCAN: 109697033(Ifngr1)
OCU: 100341787(IFNGR1)
TUP: 102475588(IFNGR1)
CFA: 100856077(IFNGR1)
VVP: 112919471(IFNGR1)
AML: 100473768(IFNGR1)
UMR: 103663370(IFNGR1)
UAH: 113259485(IFNGR1)
ORO: 101375882(IFNGR1)
ELK: 111147686
FCA: 101086811(IFNGR1)
PTG: 102952498(IFNGR1)
PPAD: 109249871(IFNGR1)
AJU: 106985768(IFNGR1)
BTA: 508619(IFNGR1)
BOM: 102275527(IFNGR1)
BIU: 109563984(IFNGR1)
BBUB: 102410135(IFNGR1)
CHX: 102182698(IFNGR1)
OAS: 101112907(IFNGR1)
SSC: 100152238(IFNGR1)
CFR: 102522759(IFNGR1)
CDK: 105092040(IFNGR1)
BACU: 103000886(IFNGR1)
LVE: 103082113(IFNGR1)
OOR: 101276054(IFNGR1)
DLE: 111166198(IFNGR1)
PCAD: 102977921(IFNGR1)
ECB: 100073195(IFNGR1)
EPZ: 103549045(IFNGR1)
EAI: 106837196(IFNGR1)
MYB: 102258073(IFNGR1)
MYD: 102761556(IFNGR1)
MNA: 107530983(IFNGR1)
HAI: 109376141 109385640(IFNGR1)
DRO: 112297082(IFNGR1)
PALE: 102888010(IFNGR1)
RAY: 107521298(IFNGR1)
MJV: 108410304(IFNGR1)
LAV: 100665172(IFNGR1)
TMU: 101345582
MDO: 100031565(IFNGR1)
SHR: 111720994(IFNGR1)
PCW: 110208928(IFNGR1)
OAA: 100078574(IFNGR1)
GGA: 421685(IFNGR1)
MGP: 100550637(IFNGR1)
CJO: 107311677(IFNGR1)
NMEL: 110395971(IFNGR1)
APLA: 101799854(IFNGR1)
ACYG: 106032518(IFNGR1)
TGU: 100222262(IFNGR1)
LSR: 110483306(IFNGR1)
SCAN: 103818469(IFNGR1)
GFR: 102034996(IFNGR1)
FAB: 101813223(IFNGR1)
PHI: 102104751(IFNGR1)
PMAJ: 107202224(IFNGR1)
CCAE: 111926795(IFNGR1)
CCW: 104689508(IFNGR1)
ETL: 114059495(IFNGR1)
FPG: 101911079(IFNGR1)
FCH: 102048414(IFNGR1)
CLV: 102085405(IFNGR1)
EGZ: 104131138(IFNGR1)
NNI: 104008886(IFNGR1)
ACUN: 113478368(IFNGR1)
PADL: 103912749(IFNGR1)
AAM: 106497894(IFNGR1)
ASN: 102374995(IFNGR1)
AMJ: 102566228(IFNGR1)
PSS: 102448524(IFNGR1)
CMY: 102936486(IFNGR1)
CPIC: 101945033(IFNGR1)
ACS: 103279436(ifngr1)
PVT: 110071491
PBI: 103056914(IFNGR1)
PMUR: 107294497(IFNGR1)
TSR: 106554510(IFNGR1)
PMUA: 114594178(IFNGR1)
GJA: 107121392(IFNGR1)
XLA: 108717881
XTR: 780275(ifngr1)
DRE: 100329124(ifngr1l) 794493(gdf10b)
IPU: 108263559(ifngr1)
PHYP: 113537513 113542090(ifngr1)
AMEX: 103034782
EEE: 113579645 113585524(ifngr1)
TRU: 105416329(ifngr1l)
LCO: 104931539(ifngr1l)
MZE: 101468425(ifngr1)
ONL: 100690512(ifngr1l)
OLA: 105357941
XCO: 114144226
PRET: 103476693
CVG: 107098124
NFU: 107375815
KMR: 108246304(ifngr1)
ALIM: 106531287
AOCE: 111583941
POV: 109630900
LCF: 108897373
SDU: 111235225(ifngr1)
SLAL: 111645304(ifngr1)
BPEC: 110157034
MALB: 109974821
OTW: 112224548 112265249(ifngr1)
ELS: 105021221(ifngr1l) 105021504
SFM: 108918633 108932840(ifngr1l)
PKI: 111837605(ifngr1) 111850737
LCM: 102362892(IFNGR1)
CMK: 103178319 103178320(ifngr1)
 » show all
Reference
PMID:2971451
  Authors
Aguet M, Dembic Z, Merlin G
  Title
Molecular cloning and expression of the human interferon-gamma receptor.
  Journal
Cell 55:273-80 (1988)
DOI:10.1016/0092-8674(88)90050-5
  Sequence
[hsa:3459]
Reference
  Authors
Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H
  Title
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.
  Journal
J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117

KEGG   ORTHOLOGY: K05133
Entry
K05133                      KO                                     

Name
IFNGR2
Definition
interferon gamma receptor 2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05164  Influenza A
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H00342  Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
   04066 HIF-1 signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05133  IFNGR2; interferon gamma receptor 2
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05133  IFNGR2; interferon gamma receptor 2
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05133  IFNGR2; interferon gamma receptor 2
   04658 Th1 and Th2 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
   04659 Th17 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05133  IFNGR2; interferon gamma receptor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05133  IFNGR2; interferon gamma receptor 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05133  IFNGR2; interferon gamma receptor 2
  09172 Infectious disease: viral
   05164 Influenza A
    K05133  IFNGR2; interferon gamma receptor 2
   05168 Herpes simplex virus 1 infection
    K05133  IFNGR2; interferon gamma receptor 2
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05133  IFNGR2; interferon gamma receptor 2
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05133  IFNGR2; interferon gamma receptor 2
   05140 Leishmaniasis
    K05133  IFNGR2; interferon gamma receptor 2
   05142 Chagas disease
    K05133  IFNGR2; interferon gamma receptor 2
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05133  IFNGR2; interferon gamma receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05133  IFNGR2; interferon gamma receptor 2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05133  IFNGR2; interferon gamma receptor 2
Other DBs
GO: 0004906
Genes
HSA: 3460(IFNGR2)
PTR: 470077(IFNGR2)
PPS: 100988947(IFNGR2)
GGO: 101144355(IFNGR2)
PON: 100442383(IFNGR2)
NLE: 105738709(IFNGR2)
MCC: 699489(IFNGR2)
MCF: 102138221(IFNGR2)
CSAB: 103216867(IFNGR2)
RRO: 104658778(IFNGR2)
RBB: 108536857(IFNGR2)
CJC: 100389763(IFNGR2)
SBQ: 101050965(IFNGR2)
MMU: 15980(Ifngr2)
MCAL: 110311588(Ifngr2)
MPAH: 110330069(Ifngr2)
RNO: 360697(Ifngr2)
MUN: 110541673(Ifngr2)
CGE: 100768877(Ifngr2)
NGI: 103736453(Ifngr2)
HGL: 101724858(Ifngr2)
CCAN: 109686803(Ifngr2)
OCU: 100338854(IFNGR2)
TUP: 102481577(IFNGR2)
CFA: 100856276(IFNGR2) 487739
VVP: 112909266(IFNGR2)
AML: 100481672(IFNGR2)
UMR: 103673221(IFNGR2)
UAH: 113264675(IFNGR2)
ELK: 111155682
FCA: 101092286(IFNGR2)
PTG: 102955729(IFNGR2)
PPAD: 109249716(IFNGR2)
AJU: 106966456(IFNGR2)
BTA: 514889(IFNGR2)
BOM: 102281523(IFNGR2)
BIU: 109569763(IFNGR2)
BBUB: 102393764(IFNGR2)
CHX: 102191269(IFNGR2)
OAS: 101122484(IFNGR2)
SSC: 100126864(IFNGR2)
CFR: 102523264(IFNGR2)
CDK: 105089867(IFNGR2)
BACU: 102997804(IFNGR2)
LVE: 103081741(IFNGR2)
OOR: 101279441(IFNGR2)
DLE: 111163885(IFNGR2)
PCAD: 102997040(IFNGR2)
ECB: 100063333(IFNGR2)
EPZ: 103549109(IFNGR2)
EAI: 106832838(IFNGR2)
MYB: 102260069(IFNGR2)
MYD: 102751646(IFNGR2)
MNA: 107537453(IFNGR2)
HAI: 109373230(IFNGR2)
DRO: 112308734(IFNGR2)
PALE: 102877930(IFNGR2)
RAY: 107519538(IFNGR2)
MJV: 108385993(IFNGR2)
LAV: 100667304(IFNGR2)
TMU: 101361970
MDO: 103106298(IFNGR2)
SHR: 100929576(IFNGR2)
PCW: 110214784(IFNGR2)
OAA: 100083438(IFNGR2)
GGA: 418502(IFNGR2)
MGP: 100542511(IFNGR2)
CJO: 107323014(IFNGR2)
NMEL: 110402478(IFNGR2)
APLA: 101790789(IFNGR2)
ACYG: 106043434(IFNGR2)
TGU: 100217912(IFNGR2)
SCAN: 103824420(IFNGR2)
GFR: 102044820(IFNGR2)
FAB: 101814771(IFNGR2)
PHI: 102110714(IFNGR2)
PMAJ: 107199716
CCAE: 111929263
CCW: 104698064(IFNGR2)
ETL: 114072364
FPG: 101919933(IFNGR2)
FCH: 102054741(IFNGR2)
CLV: 102097051(IFNGR2)
EGZ: 104128225(IFNGR2)
NNI: 104020120(IFNGR2)
ACUN: 113477857(IFNGR2)
PADL: 103920255(IFNGR2)
AAM: 106494952(IFNGR2)
ASN: 102384623(IFNGR2)
AMJ: 102568595(IFNGR2)
PSS: 102452317(IFNGR2)
CMY: 102929704(IFNGR2)
CPIC: 101942504(IFNGR2)
ACS: 103278369(ifngr2)
PVT: 110080392(IFNGR2)
PBI: 103049152(IFNGR2)
PMUR: 107290470(IFNGR2)
TSR: 106546647
PMUA: 114596051(IFNGR2)
GJA: 107121928(IFNGR2)
XTR: 100485298(ifngr2.2) 100485464(ifngr2.1)
SRX: 107747691
SANH: 107700083
SGH: 107565679
CCAR: 109064741
AMEX: 103047432
NCC: 104951796
ONL: 109194437(ifngr2-2)
AOCE: 111588419
CSEM: 103391492
POV: 109637424
LCF: 108897140
SDU: 111228112
SLAL: 111663447
HCQ: 109519275
MALB: 109951993
SASA: 106581880 106586855(IFNGR2)
SFM: 108922312(ifngr2)
 » show all
Reference
PMID:8124716
  Authors
Soh J, Donnelly RJ, Kotenko S, Mariano TM, Cook JR, Wang N, Emanuel S, Schwartz B, Miki T, Pestka S
  Title
Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor.
  Journal
Cell 76:793-802 (1994)
DOI:10.1016/0092-8674(94)90354-9
  Sequence
[hsa:3460]
Reference
  Authors
Bernabei P, Allione A, Rigamonti L, Bosticardo M, Losana G, Borghi I, Forni G, Novelli F
  Title
Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes.
  Journal
Eur Cytokine Netw 12:6-14 (2001)

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