KEGG   ORTHOLOGY: K05353
Entry
K05353                      KO                                     

Name
PMT
Definition
putrescine N-methyltransferase [EC:2.1.1.53]
Pathway
ko00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K05353  PMT; putrescine N-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.53  putrescine N-methyltransferase
     K05353  PMT; putrescine N-methyltransferase
Other DBs
RN: R01153
GO: 0030750
Genes
SLY: 101254014 778243(pmt)
SPEN: 107022573 107028024
SOT: 102580415 102598629
CANN: 107857261
NTA: 107770255(PMT4) 107771646(A411) 107799426(PMT2)
NSY: 104222427 104222428 104234743
NTO: 104100633
INI: 109170121
Reference
PMID:8038607
  Authors
Hibi N, Higashiguchi S, Hashimoto T, Yamada Y
  Title
Gene expression in tobacco low-nicotine mutants.
  Journal
Plant Cell 6:723-35 (1994)
DOI:10.1105/tpc.6.5.723
  Sequence
[nta:107771646]

KEGG   ENZYME: 2.1.1.53
Entry
EC 2.1.1.53                 Enzyme                                 

Name
putrescine N-methyltransferase;
putrescine methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:putrescine N-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + putrescine = S-adenosyl-L-homocysteine + N-methylputrescine [RN:R01153]
Reaction(KEGG)
R01153
Substrate
S-adenosyl-L-methionine [CPD:C00019];
putrescine [CPD:C00134]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N-methylputrescine [CPD:C02723]
History
EC 2.1.1.53 created 1976
Pathway
ec00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K05353  putrescine N-methyltransferase
Genes
SLY: 101254014 778243(pmt)
SPEN: 107022573 107028024
SOT: 102580415 102598629
CANN: 107857261
NTA: 107770255(PMT4) 107771646(A411) 107799426(PMT2)
NSY: 104222427 104222428 104234743
NTO: 104100633
INI: 109170121
Reference
1
  Authors
Mizusaki, S., Tanabe, Y., Noguchi, M. and Tamaki, E.
  Title
Phytochemical studies on tobacco alkaloids. XIV. The occurence and properties of putrescine N-methyltransferase in tobacco roots.
  Journal
Plant Cell Physiol 12:633-640 (1971)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.53
IUBMB Enzyme Nomenclature: 2.1.1.53
ExPASy - ENZYME nomenclature database: 2.1.1.53
BRENDA, the Enzyme Database: 2.1.1.53
CAS: 9075-39-2

KEGG   REACTION: R01153
Entry
R01153                      Reaction                               

Name
S-Adenosyl-L-methionine:putrescine N-methyltransferase
Definition
S-Adenosyl-L-methionine + Putrescine <=> S-Adenosyl-L-homocysteine + N-Methylputrescine
Equation
Reaction class
RC00003  C00019_C00021
RC00060  C00134_C02723
Enzyme
Pathway
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K05353  putrescine N-methyltransferase [EC:2.1.1.53]
Other DBs
RHEA: 15040

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