KEGG ORTHOLOGY: K05355

ORTHOLOGY: K05355

Entry

K05355                      KO

Symbol

hexPS, COQ1

Name

hexaprenyl diphosphate synthase [EC:2.5.1.82 2.5.1.83]

Pathway

map00900

Terpenoid backbone biosynthesis

map01110

Biosynthesis of secondary metabolites

Reaction

R09245

(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units)

R09246

geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
Enzymes [BR:ko01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.82  hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
     K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
    2.5.1.83  hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
     K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
Prenyltransferases [BR:ko01006]
Terpene biosynthesis
  Prenyl diphosphate synthase
   K05355  hexPS, COQ1; hexaprenyl diphosphate synthase

Other DBs

COG:

COG0142

Genes

CME:	CYME_CMJ246C

SCE:	YBR003W(COQ1)

SEUB:

DI49_0184

SPAO:

SPAR_B01070

AGO:	AGOS_AER004W

ERC:

Ecym_5300

KLA:	KLLA0_E17183g

KMX:	KLMA_60114(COQ1)

LTH:	KLTH0G16368g

VPO:	Kpol_1036p41

ZRO:	ZYRO0A04620g

CGR:	2886824(GVI51_C04037)

NCS:	NCAS_0I01970(NCAS0I01970)

NDI:	NDAI_0A06570(NDAI0A06570)

TPF:	TPHA_0A04460(TPHA0A04460)

TBL:	TBLA_0F00560(TBLA0F00560)

TGB:	HG536_0G03050

TDL:	TDEL_0D04200(TDEL0D04200)

KAF:	KAFR_0F02550(KAFR0F02550)

KNG:	KNAG_0J01180(KNAG0J01180)

ZMK:	HG535_0C02340

SLUD:

SCDLUD_002533

DHA:	DEHA2B02640g

PIC:	PICST_86778(COQ1)

PGU:	PGUG_02562

SPAA:

SPAPADRAFT_59987

LEL:	PVL30_000484(COQ1)

LBG:	92205789(LODBEIA_P05930)

CAL:	CAALFM_CR00570WA(CaO19.7478)

CTP:	CTRG_01016

COT:	CORT_0A03790

CDU:	CD36_25670

CTEN:

18246326(COQ1)

CLU:	CLUG_04350

CLUS:

A9F13_04g01595

CAUR:

CJI96_0003402

PPA:	PAS_chr4_0819

PKZ:	C5L36_0D01990

BNN:	FOA43_001379

BBRX:

BRETT_002538

OPA:	HPODL_03901

YLI:	2909963(YALI2_B00439g)

SLB:	AWJ20_394(COQ1)

NCR:

NCU02305

NTE:	NEUTE1DRAFT124027(NEUTE1DRAFT_124027)

SMP:	10801768(SMAC4_08723)

PAN:	PODANSg1807

PBEL:

QC761_509670(COQ1)

PPSD:

QC762_509670(COQ1)

PPSP:

QC763_509670(COQ1)

PPSA:

QC764_509670(COQ1)

TTT:	THITE_2117141

MTM:	MYCTH_2308814

CTHR:

MGR:

PPEI:

PGRI:

SSCK:

FGR:	FGSG_10933

FPU:	FPSE_06046

FPOA:

FPOAC1_009679

FVN:	FVRRES_10316

FVR:	FVEG_11617

FOX:	FOXG_12870

NHE:	NECHADRAFT_93238

FFC:	NCS54_00645700

FKR:	NCS57_00686000

FMU:	J7337_010022

TRE:	TRIREDRAFT_68728

TRR:	M419DRAFT_38563

TATV:

25779678(TrAtP1_008741)

TASP:

36617842(TrAFT101_002694)

MAJ:

MAA_03330

MBRN:

26246070(G6M90_00g085240)

PCHM:

VFPPC_04198

CMT:

CCM_00496

AMUS:

LMH87_000769

PLJ:	28884193(PLICBS_005461)

PTKZ:

JDV02_003904(COQ1)

VAL:	VDBG_03289

VDA:	VDAG_02194

CFJ:	CFIO01_07326

CLUP:

CLUP02_12999

CHIG:

CH63R_12248

SAPO:

SAPIO_CDS3842

ELA:	UCREL1_11765

PFY:	PFICI_14449

SSL:	SS1G_11088

BFU:	BCIN_02g05540(Bccoq1)

MBE:

MBM_07123

PSCO:

LY89DRAFT_649566

GLZ:	GLAREA_07665

ANI:	ANIA_10340

AFM:	AFUA_3G06120

ACT:	ACLA_034080

NFI:	NFIA_071130

AOR:	AO090020000085

ANG:	An11g10370

AFV:	AFLA_010570

ALUC:

AKAW2_80893A(COQ1)

ACHE:

ACHE_70473A(COQ1)

APUU:

APUU_31174S(COQ1)

PCS:	N7525_009212

PDP:	PDIP_00870

POU:	POX_g09019

TMF:	EYB26_009001

TRG:	TRUGW13939_11219

CIM:	CIMG_00484

CPW:	CPC735_057400

URE:	UREG_00522

ABE:

ARB_07252

TVE:

TRV_03960

PBL:	PAAG_05961

AJE:	HCAG_01245

BGH:	BDBG_06739

PNO:	SNOG_03045

PTE:

PTT_13690

PTRR:

6338962(PtrM4_028830)

BZE:	COCCADRAFT_107085

BSC:	COCSADRAFT_169302

BOR:	COCMIDRAFT_22591

AALT:

CC77DRAFT_951220

ARAB:

EKO05_0000542

ZTR:	MYCGRDRAFT_73426(COQ1)

PFJ:	MYCFIDRAFT_72669

FFU:	CLAFUR5_09538

CBET:

CB0940_10267

BCOM:

BAUCODRAFT_34812

NPA:	UCRNP2_7312

TML:	GSTUM_00003780001

SPO:	2541402(dps1)

SOM:	SOMG_02290(dps1)

CNE:

CNI01740

CNB:

CNBH1650

CNG:	CNAG_04375

CGI:	CGB_H2490W

CDEU:

CNBG_2676

CDEP:

91090354(L203_106146)

KMG:	30163645(I203_102858)

KNE:	92182342(IAR55_005084)

TMS:	TREMEDRAFT_15595

CCAC:

CcaHIS019_0305350(COQ1)

PPL:	POSPLDRAFT_90841

TVS:	TRAVEDRAFT_157916

DSQ:	DICSQDRAFT_173926 DICSQDRAFT_176811

PCO:	PHACADRAFT_168921

SHS:	STEHIDRAFT_71092

HIR:	HETIRDRAFT_308186

PSQ:	PUNSTDRAFT_25993

ADL:	AURDEDRAFT_110102

FME:	FOMMEDRAFT_136957

GTR:	GLOTRDRAFT_67486

LBC:	LACBIDRAFT_251291 LACBIDRAFT_335947

CCI:	CC1G_00492 CC1G_05865

ABP:	AGABI1DRAFT117445(AGABI1DRAFT_117445) AGABI1DRAFT121951(AGABI1DRAFT_121951)

ABV:	AGABI2DRAFT123328(AGABI2DRAFT_123328) AGABI2DRAFT214023(AGABI2DRAFT_214023)

PCUB:

JR316_0011391

MPR:	MPER_08383

MRR:	Moror_7207 Moror_8053

E1B28_001638 E1B28_004206

SCM:	SCHCO_02488796(SCHCODRAFT_02488796) SCHCO_02492233(SCHCODRAFT_02492233) SCHCO_02641733(SCHCODRAFT_02641733) SCHCO_02697952(SCHCODRAFT_02697952)

CPUT:

CONPUDRAFT_116134

SLA:	SERLADRAFT_444711

WSE:	WALSEDRAFT_59360

WIC:	J056_004047

UMA:	UMAG_11674

PFP:	PFL1_02050

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_00683

PTRC:

PtA15_13A363 PtA15_1A555 PtA15_1A569

PSTR:

Pst134EA_000298 Pst134EA_000303

MLR:	MELLADRAFT_102532

RIE:	OCT59_000539

DFA:	DFA_03641(coq1)

PYO:	PY17X_0301300

PCB:	PCHAS_0303000

PBE:	PBANKA_0300800

PKN:	PKNH_0418400

PVX:	PVX_003575

PCY:	PCYB_042740

FCY:	FRACYDRAFT_275453

PSOJ:

PHYSODRAFT_336262

» show all

Reference

PMID:2198286

Authors

Ashby MN, Edwards PA

Title

Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase.

Journal

J Biol Chem 265:13157-64 (1990)

Sequence

[sce:YBR003W]

All links

Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (589)   
   KEGG GENES (198)   
   KEGG MGENES (44)   
   RefGene (339)   
   OC (8)   
Literature (1)   
   PubMed (1)   
All databases (603)   

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ORTHOLOGY: K21275

Entry

K21275                      KO

Symbol

hexs-b

Name

hexaprenyl diphosphate synthase large subunit [EC:2.5.1.83]

Pathway

map00900

Terpenoid backbone biosynthesis

map01110

Biosynthesis of secondary metabolites

Reaction

R09245

(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K21275  hexs-b; hexaprenyl diphosphate synthase large subunit
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K21275  hexs-b; hexaprenyl diphosphate synthase large subunit
Enzymes [BR:ko01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.83  hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
     K21275  hexs-b; hexaprenyl diphosphate synthase large subunit
Prenyltransferases [BR:ko01006]
Terpene biosynthesis
  Prenyl diphosphate synthase
   K21275  hexs-b; hexaprenyl diphosphate synthase large subunit

Other DBs

COG:

COG0142

GO:

0036423

Genes

MACR:

MARY:

MBRU:

MEPI:

MEQU:

MBOC:

MCL:	MCCL_1121(hepB2)

MCAK:

MCCS_13080(hexs-b)

MBOE:

HT586_07190

AG:	BAA25268(hexs-b)

Reference

PMID:9515931

Authors

Shimizu N, Koyama T, Ogura K

Title

Molecular cloning, expression, and characterization of the genes encoding the two essential protein components of Micrococcus luteus B-P 26 hexaprenyl diphosphate synthase.

Journal

J Bacteriol 180:1578-81 (1998)
DOI:10.1128/JB.180.6.1578-1581.1998

Sequence

[ag:BAA25268]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (11)   
   KEGG GENES (10)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (24)   

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ORTHOLOGY: K21274

Entry

K21274                      KO

Symbol

hexs-a

Name

hexaprenyl diphosphate synthase small subunit [EC:2.5.1.83]

Pathway

map00900

Terpenoid backbone biosynthesis

map01110

Biosynthesis of secondary metabolites

Reaction

R09245

(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K21274  hexs-a; hexaprenyl diphosphate synthase small subunit
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K21274  hexs-a; hexaprenyl diphosphate synthase small subunit
Enzymes [BR:ko01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.83  hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
     K21274  hexs-a; hexaprenyl diphosphate synthase small subunit
Prenyltransferases [BR:ko01006]
Terpene biosynthesis
  Prenyl diphosphate synthase
   K21274  hexs-a; hexaprenyl diphosphate synthase small subunit

Other DBs

GO:

0036423

Genes

MACR:

MARY:

MBRU:

MEPI:

MBOC:

MCL:	MCCL_1123(hepB1)

MCAK:

MCCS_13100(hexs-a)

MBOE:

HT586_07200

AG:	BAA25266(hexs-a)

Reference

PMID:9515931

Authors

Shimizu N, Koyama T, Ogura K

Title

Molecular cloning, expression, and characterization of the genes encoding the two essential protein components of Micrococcus luteus B-P 26 hexaprenyl diphosphate synthase.

Journal

J Bacteriol 180:1578-81 (1998)
DOI:10.1128/JB.180.6.1578-1581.1998

Sequence

[ag:BAA25266]

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (10)   
   KEGG GENES (9)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (22)   

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