KEGG ORTHOLOGY: K05473

ORTHOLOGY: K05473

Entry

K05473                      KO

Symbol

TNFSF11, RANKL, CD254

Name

tumor necrosis factor ligand superfamily member 11

Pathway

map04060

Cytokine-cytokine receptor interaction

map04064

NF-kappa B signaling pathway

map04380

Osteoclast differentiation

map04917

Prolactin signaling pathway

map04928

Parathyroid hormone synthesis, secretion and action

map05207

Chemical carcinogenesis - receptor activation

map05224

Breast cancer

map05323

Rheumatoid arthritis

Disease

H00436

Osteopetrosis

H01470

Giant cell tumor of bone

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04928 Parathyroid hormone synthesis, secretion and action
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09162 Cancer: specific types
   05224 Breast cancer
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04090 CD molecules
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Tumor necrosis fators
   K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
CD molecules [BR:ko04090]
Proteins
  K05473  CD254, TNFSF11; tumor necrosis factor (ligand) superfamily, member 11

Other DBs

GO:

0005164

Genes

HSA:	8600(TNFSF11)

PTR:	467353(TNFSF11)

PPS:	100994539(TNFSF11)

GGO:	101131644(TNFSF11)

PON:	100439883(TNFSF11)

PPYG:

129011568(TNFSF11)

NLE:	100599838(TNFSF11)

HMH:	116467215(TNFSF11)

SSYN:

129463521(TNFSF11)

MCC:	699955(TNFSF11)

MCF:	102137946(TNFSF11)

MTHB:

126940380

MNI:	105491723(TNFSF11)

CSAB:

103214344(TNFSF11)

CATY:

105587810(TNFSF11)

PANU:

101026064(TNFSF11)

TGE:	112610939(TNFSF11)

MLEU:

105535517(TNFSF11)

RRO:	104671084(TNFSF11)

RBB:	108514105(TNFSF11)

TFN:	117096667(TNFSF11)

PTEH:

111540414(TNFSF11)

CANG:

105510559(TNFSF11)

CJC:	100401379(TNFSF11)

SBQ:	101051208(TNFSF11)

CIMI:

108309685(TNFSF11)

ANAN:

105731687(TNFSF11)

CSYR:

103264833(TNFSF11)

MMUR:

105869318(TNFSF11)

LCAT:

123648860(TNFSF11)

PCOQ:

105813945(TNFSF11)

OGA:	100964778(TNFSF11)

MMU:	21943(Tnfsf11)

MCAL:

110309649(Tnfsf11)

MPAH:

110325778(Tnfsf11)

RNO:	117516(Tnfsf11)

MCOC:

116084439(Tnfsf11)

ANU:	117705932(Tnfsf11)

MUN:	110562414(Tnfsf11)

CGE:	100768715(Tnfsf11)

MAUA:

101827402(Tnfsf11)

PROB:

127230483(Tnfsf11)

PLEU:

114699851(Tnfsf11)

MORG:

121464236(Tnfsf11)

AAMP:

119800481(Tnfsf11)

NGI:	103751291(Tnfsf11)

HGL:	101696350(Tnfsf11)

CPOC:

100713226(Tnfsf11)

CCAN:

109700348(Tnfsf11)

DORD:

105998104(Tnfsf11)

DSP:	122112694(Tnfsf11)

PLOP:

125347869(Tnfsf11)

NCAR:

124985349

MMMA:

107140871(Tnfsf11)

OCU:

100341009

OPI:	101526376 101532341(TNFSF11)

TUP:	102487682(TNFSF11)

GVR:	103608964(TNFSF11)

CFA:	609418(TNFSF11)

CLUD:

112678837(TNFSF11)

VVP:	112928102(TNFSF11)

VLG:	121477078(TNFSF11)

NPO:	129516607(TNFSF11)

AML:	100483079(TNFSF11)

UMR:	103677566(TNFSF11)

UAH:	113251369(TNFSF11)

UAR:	123801101(TNFSF11)

ELK:

111147123

LLV:

125094634

MPUF:

101672512 101682798(TNFSF11)

MNP:	132002474(TNFSF11)

MLK:	131813956(TNFSF11)

NVS:	122907860(TNFSF11)

ORO:	101376926(TNFSF11)

EJU:	114211677(TNFSF11)

ZCA:	113920567(TNFSF11)

MLX:	118009176(TNFSF11)

NSU:	110587728(TNFSF11)

LWW:

102744110

FCA:	724036(TNFSF11)

PYU:	121013014(TNFSF11)

PCOO:

112860814(TNFSF11)

PBG:	122483032(TNFSF11)

PVIV:

125146779(TNFSF11)

LRUF:

124512581

PTG:	102954463(TNFSF11)

PPAD:

109265885(TNFSF11)

PUC:

125933815

AJU:

106971982

HHV:	120248657(TNFSF11)

BTA:	513836(TNFSF11)

BOM:	102267691(TNFSF11)

BIU:	109566677(TNFSF11)

BBUB:

102393260(TNFSF11)

BBIS:

104999126(TNFSF11)

CHX:	102176335(TNFSF11)

OAS:	100037694(TNFSF11)

BTAX:

128057835(TNFSF11)

ODA:	120883183(TNFSF11)

CCAD:

122447465(TNFSF11)

MBEZ:

129556590(TNFSF11)

SSC:	100037976(TNFSF11)

CFR:	102507742(TNFSF11)

CBAI:

105083435(TNFSF11)

CDK:	105089768(TNFSF11)

VPC:	102533548(TNFSF11)

BACU:

103002678(TNFSF11)

BMUS:

118884331(TNFSF11)

LVE:	103074658(TNFSF11)

OOR:	101284929(TNFSF11)

DLE:	111175123(TNFSF11)

PCAD:

102978976(TNFSF11)

PSIU:

116743210(TNFSF11)

NASI:

112406633(TNFSF11)

ECB:	100060254(TNFSF11)

EPZ:	103560371(TNFSF11)

EAI:	106847554(TNFSF11)

MYB:	102260756(TNFSF11)

MYD:	102751742(TNFSF11)

MMYO:

118651542(TNFSF11)

MLF:	102427077(TNFSF11)

MDT:	132228392(TNFSF11)

PKL:	118730609(TNFSF11)

EFUS:

103289655(TNFSF11)

MNA:	107531354(TNFSF11)

DRO:	112311127(TNFSF11)

SHON:

118997034(TNFSF11)

AJM:	119042868(TNFSF11)

PDIC:

114508772(TNFSF11)

PHAS:

123818869(TNFSF11)

MMF:	118622793(TNFSF11)

PPAM:

129081082(TNFSF11)

HAI:	109386844(TNFSF11)

RFQ:	117021430(TNFSF11)

PALE:

102896284(TNFSF11)

PGIG:

120614450(TNFSF11)

PVP:	105298465(TNFSF11)

RAY:	107517455(TNFSF11)

MJV:	108407315(TNFSF11)

TOD:	119259662(TNFSF11)

SARA:

101547843(TNFSF11)

SETR:

126016258(TNFSF11)

LAV:	100663523(TNFSF11)

TMU:

101342165

ETF:	101659751(TNFSF11)

DNM:	101429635(TNFSF11)

MDO:	100011641(TNFSF11)

GAS:	123240037(TNFSF11)

SHR:	105750026(TNFSF11)

AFZ:

127553269

PCW:	110201421(TNFSF11)

TVP:	118848606(TNFSF11)

OAA:	100076541(TNFSF11)

GGA:	428067(TNFSF11)

PCOC:

116244153(TNFSF11)

MGP:	104917524(TNFSF11)

CJO:	107308113(TNFSF11)

TPAI:

128092110(TNFSF11)

LMUT:

125685116(TNFSF11)

NMEL:

110387248(TNFSF11)

APLA:

101803149(TNFSF11)

ACYG:

106035087(TNFSF11)

CATA:

118251346(TNFSF11)

AFUL:

116501867(TNFSF11)

TGU:	100227247(TNFSF11)

LSR:	110470890(TNFSF11)

SCAN:

103812581(TNFSF11)

PMOA:

120505810(TNFSF11)

OTC:	121337314(TNFSF11)

PRUF:

121353320(TNFSF11)

GFR:	102038556(TNFSF11)

FAB:	101822088(TNFSF11)

OMA:	130255404(TNFSF11)

PHI:	102111124(TNFSF11)

PMAJ:

107212828(TNFSF11)

CCAE:

111935210(TNFSF11)

CCW:	104693175(TNFSF11)

CBRC:

103615178(TNFSF11)

ETL:	114059881(TNFSF11)

ZAB:	102064010(TNFSF11)

ZLE:	135453283(TNFSF11)

ACHL:

103798173(TNFSF11)

SVG:	106862463(TNFSF11)

MMEA:

130573697(TNFSF11)

HRT:	120749051(TNFSF11)

SATI:

136357779(TNFSF11)

FPG:	101919009(TNFSF11)

FCH:	102050665(TNFSF11)

CCRI:

104165582(TNFSF11)

NNT:	104411387(TNFSF11)

SHAB:

115603892(TNFSF11)

ACUN:

113480179(TNFSF11)

TALA:

104358598(TNFSF11)

ACHC:

115350784(TNFSF11)

HALD:

104319076(TNFSF11)

HLE:	104837359(TNFSF11)

AGEN:

126045137

GCL:

127026989

CSTI:

104562176(TNFSF11)

LDI:	104340678(TNFSF11)

MNB:	103776876(TNFSF11)

DPUB:

104306580(TNFSF11)

BRHI:

104489276(TNFSF11)

EGZ:	104132030(TNFSF11)

NNI:	104010922(TNFSF11)

PCRI:

104036929(TNFSF11)

PCAO:

104050873(TNFSF11)

PADL:

103915905(TNFSF11)

AFOR:

103895905(TNFSF11)

FGA:	104079157(TNFSF11)

GSTE:

104257775(TNFSF11)

CLV:	102098042(TNFSF11)

MUI:	104537437(TNFSF11)

PGUU:

104470509(TNFSF11)

PLET:

104615248(TNFSF11)

EHS:	104516909(TNFSF11)

CMAC:

104480985(TNFSF11)

CUCA:

104056514(TNFSF11)

TEO:	104370798(TNFSF11)

BREG:

104636927(TNFSF11)

OHA:	104336935(TNFSF11)

ACAR:

104526293(TNFSF11)

CPEA:

104391534(TNFSF11)

CVF:	104293445(TNFSF11)

RTD:	128911728(TNFSF11)

AAM:	106489200(TNFSF11)

AROW:

112962605(TNFSF11)

NPD:	112943361(TNFSF11)

TGT:	104572592(TNFSF11)

DNE:	112982655(TNFSF11)

SCAM:

104142482(TNFSF11)

ASN:	102387902(TNFSF11)

AMJ:	102559854(TNFSF11)

CPOO:

109305514(TNFSF11)

GGN:	109302252(TNFSF11)

PSS:	102444457(TNFSF11)

CMY:	102947527(TNFSF11)

CCAY:

125637087(TNFSF11)

DCC:	119841216(TNFSF11)

CPIC:

101936501(TNFSF11)

TST:	117871596(TNFSF11)

CABI:

116817999(TNFSF11)

MRV:	120396036(TNFSF11)

ACS:	100566737(tnfsf11)

ASAO:

132771343(TNFSF11)

PVT:	110084678(TNFSF11)

SUND:

121926338(TNFSF11)

PMUR:

107283208(TNFSF11)

CTIG:

120318729(TNFSF11)

PGUT:

117667006(TNFSF11)

APRI:

131199213(TNFSF11)

PTEX:

113439469(TNFSF11)

NSS:

113429675

VKO:	123032407(TNFSF11)

PMUA:

114600094(TNFSF11)

PRAF:

128417981(TNFSF11)

ZVI:	118079346(TNFSF11)

HCG:	128351121(TNFSF11)

GJA:	107123862(TNFSF11)

STOW:

125430486(TNFSF11)

EMC:	129325960(TNFSF11)

XLA:	496322(tnfsf11.L) 733333(tnfsf11.S)

XTR:	100038074(tnfsf11)

NPR:	108790250(TNFSF11)

RTEM:

120929646(TNFSF11)

BGAR:

122932374(TNFSF11)

MUO:	115468661(TNFSF11)

GSH:	117361986(TNFSF11)

SRX:	107713713 107749039(tnfsf11)

SANH:

107661329(tnfsf11) 107688674

SGH:

CCAR:

CAUA:

AMEX:

EEE:

MZE:	101482899(tnfsf11)

ONL:

100690570

OAU:	116310490(tnfsf11)

XMA:	102231551(tnfsf11)

XCO:	114148628(tnfsf11)

PRET:

103481812(tnfsf11)

CVG:

107101899

SASA:

106575455 106582173 106582220 106586517(tnfsf11) 106592211

OTW:	112225511 112235911 112236954 112239917(tnfsf11)

OMY:	100136320 110501712(tnfsf11) 110520367 110527377

SALP:

111978065(tnfsf11) 112074051 112075152 112080705

ELS:	105016373 105019817

SFM:	108920497(tnfsf11) 108928984

PSPA:

121321280 121327682

LCM:	102363811(TNFSF11)

SPU:

115922601

HRF:

124125943

CRG:	105326163 105344501

MMER:

123526486

MAEA:

128220400 128220462 128220690 128220699

» show all

Reference

PMID:9367155

Authors

Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L

Title

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Journal

Nature 390:175-9 (1997)
DOI:10.1038/36593

Sequence

[hsa:8600]

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (1)   
   KEGG DRUG (1)   
Gene (404)   
   KEGG GENES (322)   
   KEGG MGENES (60)   
   RefGene (21)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (428)   

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