KEGG   ORTHOLOGY: K05555
Entry
K05555                      KO                                     

Name
actIV
Definition
cyclase [EC:4.-.-.-]
Pathway
ko01057  Biosynthesis of type II polyketide products
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K05555  actIV; cyclase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K05555  actIV; cyclase
Enzymes [BR:ko01000]
 4. Lyases
  4.-  
   4.-.-  
    4.-.-.-  
     K05555  actIV; cyclase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C12 cyclized polyketide type
    Octaketide PKS
     K05555  actIV; cyclase
Other DBs
RN: R09305
COG: COG0491
Genes
STEM: CLM74_11295
LAB: LA76x_5067
LAQ: GLA29479_380
LCP: LC55x_1872 LC55x_5553
LGU: LG3211_2964
LMB: C9I47_1763
LPY: FIV34_00110
PAGR: E2H98_04600
SDN: Sden_2195
SFR: Sfri_2384
SAZ: Sama_1415
SLO: Shew_1646
SSE: Ssed_2823
SWD: Swoo_1827
SWP: swp_2280
SPSW: Sps_01639
SKH: STH12_01048(gloB_1)
ILO: IL0617
CPS: CPS_3350
PHA: PSHAa0080
PAT: Patl_0462
PSM: PSM_A0082
PSEO: OM33_03600
PSPO: PSPO_a0079
PART: PARC_a3854
PSEN: PNC201_22130(gloB4)
PAGA: PAGA_a0101
AMAL: I607_16350
AMAE: I876_16655
AMAO: I634_16605
AMAD: I636_16540
AMAI: I635_17285
AMAG: I533_16195
AMAC: MASE_16180
AAUS: EP12_16910
ASP: AOR13_62
GNI: GNIT_0776
GPS: C427_0453
FBL: Fbal_2496
SDE: Sde_1764
SAGA: M5M_00830
MICT: FIU95_17130(cphA)
CYQ: Q91_2164
TGR: Tgr7_0582
TKM: TK90_1033
TVR: TVD_01155
KGE: TQ33_1801
TOL: TOL_2603
ABU: Abu_0578
ATP: ATR_1136
AELL: AELL_0723
AAQI: AAQM_0624
ACIB: ACBT_1719
HBV: ABIV_1372
PACO: AACT_0825
ARC: ABLL_0700
SUN: SUN_0503
SCL: sce5265
AMIH: CO731_01275(cphA)
PLA: Plav_1652
RBS: RHODOSMS8_02618(gloB)
EAD: OV14_1184
MMED: Mame_03788
HNE: HNE_3461
GAK: X907_0337
SSAN: NX02_05750
SSY: SLG_28590
ELI: ELI_06065
AAY: WYH_01851(gloB_2)
ADO: A6F68_02359(gloB_1)
BTHI: BTK_30119
BMYC: DJ92_4955
LSP: Bsph_2908
PSYO: PB01_06350
PPM: PPSC2_03230(M1-763)
PPO: PPM_0588(M1-763)
PPQ: PPSQR21_006220(gloB)
PSAB: PSAB_07645
MSAL: DSM43276_02539(ccrA)
RHB: NY08_4670
RHU: A3Q40_02982(cphA)
SRT: Srot_1974
SCO: SCO5091(actIV)
SFA: Sfla_1397
SBH: SBI_02671
SVE: SVEN_1290
STRP: F750_5486
SALU: DC74_2171
SALL: SAZ_11435
SLD: T261_6529
STRM: M444_08775
SRW: TUE45_01293(ccrA) TUE45_01564(cphA)
SRN: A4G23_00927(cphA)
SMAL: SMALA_7388
SALJ: SMD11_0679(actIV) SMD11_5327(actIV)
SLX: SLAV_29025(ccrA2) SLAV_40525(ccrA3)
NCA: Noca_1178
NDA: Ndas_1240
NAL: B005_3938
SRO: Sros_6284
SEN: SACE_3955
AMYY: YIM_19405
PDX: Psed_3907
PSEE: FRP1_23695
PSEH: XF36_22350
PAUT: Pdca_03850
KAL: KALB_4268
ASE: ACPL_2714
ACTN: L083_2689
ACTS: ACWT_2832
CAI: Caci_6499
SNA: Snas_1269
AFO: Afer_1344
OTE: Oter_0578
OBG: Verru16b_00999(ccrA)
PIR: VN12_09965(gloB_1)
GES: VT84_32290(cphA)
AGV: OJF2_76200(cphA_3)
ABAS: ACPOL_6064
SUS: Acid_4392
ABAC: LuPra_03798(blaB1)
SRU: SRU_1352
SRM: SRM_01546
RMR: Rmar_0583
GFO: GFO_2388
CBAL: M667_07690
CBAT: M666_07725
DDO: I597_1068(cphA)
MPW: MPR_0514
TMAR: MARIT_2048
KOS: KORDIASMS9_01733(cphA)
KAN: IMCC3317_35680(cphA_2)
FBA: FIC_00381
MRO: MROS_1010
SOL: Ssol_0326
SSOA: SULA_0319
SSOL: SULB_0321
SSOF: SULC_0319
SID: M164_0329
SII: LD85_0313
SIH: SiH_0314
SIR: SiRe_0313
SIC: SiL_0296
VDI: Vdis_1898
 » show all
Reference
  Authors
Hopwood DA
  Title
Genetic Contributions to Understanding Polyketide Synthases.
  Journal
Chem Rev 97:2465-2498 (1997)
DOI:10.1021/cr960034i

KEGG   REACTION: R09305
Entry
R09305                      Reaction                               

Definition
7,9,12-Octaketide intermediate 3 <=> Octaketide bicyclic intermediate + H2O
Equation
Comment
cyclase, actIV
Enzyme
4.-.-.-
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Orthology
K05555  cyclase [EC:4.-.-.-]

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