KEGG ORTHOLOGY: K05641

ORTHOLOGY: K05641

Entry

K05641                      KO

Symbol

ABCA1

Name

ATP-binding cassette, subfamily A (ABC1), member 1

Pathway

map02010

ABC transporters

map04975

Fat digestion and absorption

map04979

Cholesterol metabolism

map05417

Lipid and atherosclerosis

Disease

H00159

Tangier disease

H00930

Hypoalphalipoproteinemia

H02505

Atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
   04979 Cholesterol metabolism
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
Transporters [BR:ko02000]
ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1

Other DBs

TC:

3.A.1.211

Genes

HSA:

19(ABCA1)

PTR:	464630(ABCA1)

PPS:	100971870(ABCA1)

GGO:	101151472(ABCA1)

PON:	100441342(ABCA1)

NLE:	100606619(ABCA1)

HMH:	116475500(ABCA1)

MCC:	716146(ABCA1)

MCF:	102117645(ABCA1)

MTHB:

126937939

MNI:	105481013(ABCA1)

CSAB:

103219077(ABCA1)

CATY:

105600323(ABCA1)

PANU:

100997056(ABCA1)

TGE:	112607819(ABCA1)

MLEU:

105529293(ABCA1)

RRO:	104654215(ABCA1)

RBB:	108532571(ABCA1)

TFN:	117098885(ABCA1)

PTEH:

111536142(ABCA1)

CANG:

105516145(ABCA1)

CJC:	100403133(ABCA1)

SBQ:	101046397(ABCA1)

CIMI:

108303831(ABCA1)

CSYR:

103276045(ABCA1)

MMUR:

105855724(ABCA1)

LCAT:

123646642(ABCA1)

PCOQ:

105805614(ABCA1)

OGA:	100964745(ABCA1)

MMU:	11303(Abca1)

MCAL:

110292559(Abca1)

MPAH:

110323695(Abca1)

RNO:	313210(Abca1)

MCOC:

116096020(Abca1)

ANU:	117708490(Abca1)

MUN:	110565774 110565778

CGE:	100761226(Abca1)

MAUA:

101838333(Abca1)

PROB:

127224699(Abca1)

PLEU:

114683448(Abca1)

MORG:

121451264(Abca1)

MFOT:

126515248

AAMP:

119826167(Abca1)

NGI:	103748921(Abca1)

HGL:	101704546(Abca1)

CPOC:

100720792(Abca1)

CCAN:

109691834(Abca1)

DORD:

105990807(Abca1)

DSP:	122123988(Abca1)

NCAR:

124964198

OCU:

100356765

OPI:	101516816(ABCA1)

TUP:	102489626(ABCA1)

GVR:	103603356(ABCA1)

CFA:	481651(ABCA1)

CLUD:

112650438(ABCA1)

VVP:	112922973(ABCA1)

VLG:	121495748(ABCA1)

AML:	100483394(ABCA1)

UMR:

103678544

UAH:	113260353(ABCA1)

UAR:	123781247(ABCA1)

ELK:

111145612

LLV:

125083984

MPUF:

101679430(ABCA1)

NVS:	122917384(ABCA1)

ORO:	101382837(ABCA1)

EJU:	114213494(ABCA1)

ZCA:	113934154(ABCA1)

MLX:	118017859(ABCA1)

NSU:

110581396

LWW:

102740136

FCA:	101083885(ABCA1)

PYU:

121034775

PBG:	122474526(ABCA1)

LRUF:

124502632

PTG:	102960483(ABCA1)

PPAD:

109270041(ABCA1)

PUC:

125926245

AJU:	106979364(ABCA1)

HHV:	120236994(ABCA1)

BTA:	535379(ABCA1)

BOM:	102280059(ABCA1)

BIU:	109563312(ABCA1)

BBUB:

102400056(ABCA1)

BBIS:

104991148(ABCA1)

CHX:	102179197(ABCA1)

OAS:	101119015(ABCA1)

ODA:	120864128(ABCA1)

CCAD:

122431656(ABCA1)

SSC:	100152112(ABCA1)

CFR:	102509338(ABCA1)

CBAI:

105067419(ABCA1)

CDK:	105087915(ABCA1)

VPC:	102536620(ABCA1)

BACU:

103004596(ABCA1)

LVE:	103070957(ABCA1)

OOR:	101273707(ABCA1)

DLE:	111188018(ABCA1)

PCAD:

102979910(ABCA1)

PSIU:

116755343(ABCA1)

NASI:

112405299(ABCA1)

ECB:	100054241(ABCA1)

EPZ:	103555518(ABCA1)

EAI:	106830496(ABCA1)

MYB:	102244473(ABCA1)

MYD:	102769534(ABCA1)

MMYO:

118667229(ABCA1)

MLF:	102428362(ABCA1)

MNA:	107546564(ABCA1)

PKL:	118716232(ABCA1)

HAI:	109371278(ABCA1)

DRO:	112304621(ABCA1)

SHON:

118979609(ABCA1)

AJM:	119034850(ABCA1)

PDIC:

114491332(ABCA1)

PHAS:

123819577(ABCA1)

MMF:	118629930(ABCA1)

RFQ:	117031810(ABCA1)

PALE:

102885306(ABCA1)

PGIG:

120608703(ABCA1)

PVP:	105295342(ABCA1)

RAY:	107516398(ABCA1)

MJV:	108409431(ABCA1)

TOD:	119232987(ABCA1)

SARA:

101543604(ABCA1)

LAV:	100666529(ABCA1)

TMU:

101352346

ETF:	101643958(ABCA1)

DNM:	101417886(ABCA1)

MDO:	100013781(ABCA1)

GAS:	123248973(ABCA1)

SHR:	100921930(ABCA1)

AFZ:

127541818

PCW:	110214477(ABCA1)

OAA:	100075984(ABCA1)

GGA:	373945(ABCA1) 770610(ABCA7)

PCOC:

116235807(ABCA7) 116238178(ABCA1)

MGP:	100542147(ABCA7) 100545145(ABCA1)

CJO:	107306430(ABCA1) 107325421(ABCA7)

NMEL:

110388803(ABCA7) 110389287(ABCA1)

APLA:

101796019(ABCA1) 113845670(ABCA7)

ACYG:

106040434(ABCA1) 106048214(ABCA7)

AFUL:

116499079(ABCA7) 116500367(ABCA1)

TGU:	100220408(ABCA7) 100220820(ABCA1)

LSR:	110472799(ABCA1) 110475771(ABCA7)

SCAN:

103821238(ABCA1) 103822044(ABCA7)

PMOA:

120495881(ABCA7) 120509438(ABCA1)

OTC:	121337404(ABCA1) 121342328(ABCA7)

PRUF:

121355319(ABCA1) 121361621(ABCA7)

GFR:	102037171(ABCA7) 102041458(ABCA1)

FAB:	101807730(ABCA1) 101817174(ABCA7)

PHI:	102112452(ABCA1) 102113780(ABCA7)

PMAJ:

107215571(ABCA7) 107216038(ABCA1)

CCAE:

111941779

CCW:	104689733(ABCA1) 104697058(ABCA7)

CBRC:

103619199(ABCA1) 103622180(ABCA7)

ETL:	114063104(ABCA1) 114066412(ABCA7)

ZAB:	102065315 102073466(ABCA1)

ACHL:

103812191(ABCA1)

SVG:	106856781(ABCA1) 106857049(ABCA7)

FPG:	101912854(ABCA7) 101913242(ABCA1)

FCH:	102047305(ABCA7) 102056980(ABCA1)

CLV:	102096351(ABCA1)

EGZ:	104123362(ABCA1) 104127389(TMEM259)

NNI:	104011942(ABCA1) 104016304(ABCA7)

PLET:

104625707(ABCA1)

PCRI:

104036546(ABCA1)

PCAO:

104042203(ABCA1)

ACUN:

113490020(ABCA1)

TALA:

104363706(ABCA1) 116961656(ABCA7)

PADL:

103925589(ABCA1)

AFOR:

103899418(ABCA7) 103904745(ABCA1)

ACHC:

115336503(ABCA1) 115349417(ABCA7)

HALD:

104325345(ABCA1)

HLE:	104829162(ABCA7) 104830367(ABCA1)

AGEN:

126036024 126041732

GCL:	127025422 127027864

CCRI:

104164017

CSTI:

104554333(ABCA1)

EHS:

104507713

CMAC:

104482154(ABCA1)

MUI:	104538664(ABCA1)

FGA:

104073687

GSTE:

104257150(ABCA1)

LDI:	104353274(ABCA1)

MNB:	103781919(ABCA1)

OHA:	104330147(ABCA1)

NNT:	104406982(ABCA1)

SHAB:

115601086(ABCA1) 115618018(ABCA7)

DPUB:

104300557(ABCA7) 104305773(ABCA1)

PGUU:

104463807

ACAR:

104530827(ABCA1)

CPEA:

104389216(ABCA1)

AVIT:

104278423(ABCA1)

CVF:	104288405(ABCA1)

CUCA:

104062628(ABCA1) 104065780(ABCA7)

TEO:	104383375(ABCA1)

BRHI:

104495113(ABCA1)

AAM:	106482494(ABCA1) 106483819

AROW:

112965609(ABCA7) 112972308(ABCA1)

NPD:	112946820(ABCA7) 112956409(ABCA1)

TGT:	104572789(ABCA1)

DNE:	112982179(ABCA1) 112988093(ABCA7)

SCAM:

104145395 104152276(ABCA1)

ASN:	102384149(ABCA1) 102387412(ABCA7)

AMJ:	102571038(ABCA7) 102572232(ABCA1)

CPOO:

109312396(ABCA7) 109323437(ABCA1)

GGN:	109294707(ABCA7) 109297382(ABCA1)

PSS:	102456667(ABCA1)

CMY:	102929738(ABCA7) 102937788(ABCA1)

CPIC:

101946886(ABCA7) 101953849(ABCA1)

TST:	117868945(ABCA7) 117878699(ABCA1)

CABI:

116820644(ABCA1) 116828036(ABCA7)

MRV:	120391651(ABCA7) 120407992(ABCA1)

ACS:	100557081(abca1)

PVT:	110083188(ABCA1) 110090586

SUND:

121923340(ABCA1) 121937012

PBI:	103054084(ABCA1)

PMUR:

107286307(ABCA1)

CTIG:

120311453(ABCA1)

TSR:

106544862

PGUT:

117661626(ABCA1)

VKO:	123030168(ABCA1) 123035370

PMUA:

114587887(ABCA1) 114588678

ZVI:	118075295(ABCA1) 118086011(ABCA7)

GJA:	107113264(ABCA1) 107121240

STOW:

125433286(ABCA7) 125436299(ABCA1)

XLA:	108695393(abca1.L) 108706934(abca1.S)

XTR:	100491942(abca1)

NPR:	108794435(ABCA1)

RTEM:

120945316(ABCA1)

BBUF:

120989240(ABCA1)

BGAR:

122943763

DRE:	100136868(abca1b) 558924(abca1a) 561460(zgc:172302)

SRX:	107746118 107746538 107749001 107751334

SANH:

107657990 107660187 107680923 107693596 107697642 107703854

SGH:	107550538 107551454 107570823 107571910 107587072

CAUA:

113044077 113051740 113057663 113062362 113069428 113084554

CGIB:

127949061 127968208 127971332 128020414 128027637

PPRM:

120460992(abca1b) 120467738(abca7) 120477781 120488784(abca1a)

MAMB:

125256828(abca7) 125259439(abca1b) 125265746 125271865(abca1a)

CIDE:

127494142 127510572 127522257

MASI:

127412709 127417585 127426586 127443777 127444698

IPU:	108260577 108260597(abca1a) 108271263(abca7) 108275029(abca1b)

PHYP:

113524513 113530168 113531670 113545719

SMEO:

124381152(abca1a) 124381467 124390866(abca7) 124391901(abca1b)

TFD:	113635483 113641416(abca1a) 113657690(abca7) 113659876(abca1b)

AMEX:

103028164 103039328 103041974 103044029

EEE:	113581313 113581902 113583881 113589944

TRU:	101069457 101069691 101075114 105418367

TNG:	GSTEN00012070G001 GSTEN00012848G001 GSTEN00021323G001 GSTEN00033523G001

LCO:	104928391 104933941 104936080

NCC:	104958945(abca1) 104962031(abca7)

CGOB:

115005428 115006861 115014543

ELY:	117246311 117253983(zgc:172302) 117255906 117259820(abca1b)

EFO:	125883941 125885909 125894365(abca1b) 125895657(abca7)

PLEP:

121941839 121961901 121965345(abca7)

SLUC:

116039899 116042878 116051164 116055197(zgc:172302) 116060261

ECRA:

117934569 117936722 117950885(zgc:172302)

ESP:	116694873 116698112(abca1) 116707246

PFLV:

114546160 114547436(abca1) 114561119 114563296 114563299 114563313

GAT:	120817300(abca1b) 120822748 120823593(abca7) 120824562

PPUG:

119211440(abca1b) 119216535(zgc:172302) 119218439 119222665

MSAM:

119888329(abca1b) 119899363 119900515(abca7) 119911855

CUD:	121504174 121508842 121512157(abca7) 121516223(abca1b)

ALAT:

119007280(abca1b) 119027099 119028482(zgc:172302) 119032235

MZE:	101467088 101473399 101476448 101484083

ONL:	100691919 100694252 100699821 100700665 102079432 102082389

OAU:	116313301 116316888(abca7) 116332055(abca1b) 116333175

OLA:	101162276 101163147 101163308 101164844

OML:	112140337 112150479(zgc:172302) 112153262(abca1b) 112156111

XMA:	102226743 102233672 102236954 111610924

XCO:	114139598 114143839 114151381 114157570

XHE:	116714577 116719324 116726268 116732982

PRET:

103463358(abca7) 103469417 103471778 103480793

PFOR:

103143858 103146371 103148755 103155995

PLAI:

106936168 106939775 106944166 106959213

PMEI:

106904934 106908893 106920112 106930199

GAF:	122820345 122829792 122836776(abca1b) 122839091(abca7)

CVG:	107082707 107096934 107096983 107101107

CTUL:

119784578(abca1b) 119787056 119798788(abca7)

GMU:	124860377(abca1b) 124868167 124874383(abca7) 124880928

NFU:	107372735 107377411 107381037 107391047 107392625

KMR:	108234389(zgc:172302) 108234870 108241480 108248967(abca1b)

ALIM:

106514836 106516777(abca7) 106520201 106528335

NWH:	119407681(abca7) 119408377(abca1b) 119422387 119426037

AOCE:

111565691 111570931 111575002 111584566

MCEP:

125004626 125008280 125009662(abca7) 125012690

CSEM:

103384135 103390790 103390832 103395872(abca7)

POV:	109627531(abca1) 109634879 109636653

SSEN:

122764928 122770720 122780867(abca7)

HHIP:

117751749 117760445(zgc:172302) 117769080(abca1b) 117769461

HSP:	118102796 118112351(abca1b) 118115595 118120801(abca7)

LCF:	108877448 108885292 108885358 108892258

SDU:	111229245 111231607 111233496 111235088

SLAL:

111659723 111665601 111665943 111669992

XGL:	120785452(abca1b) 120791087(abca7) 120797184 120799665

HCQ:	109508321 109519093 109519834(abca1) 109520361 109526180

SSCV:

125969191 125974896 125977512 125990107

BPEC:

110159332 110162848 110165876 110166147(abca1)

MALB:

109951103 109966555 109966849 109970682

BSPL:

114850366 114853524(abca7) 114863520 114864568(abca1b)

SASA:

106573884 106577627 106602602 106604636 106608787 106609880 106611642

STRU:

115151695 115171529 115191837 115194265 115198266 115202191 115205170

OTW:	112220988(abca1b) 112232763 112245029 112252146(abca7) 112256275 112259966 112261350

OMY:	110488861(abca1b) 110494857(zgc:172302) 110498663 110500599 110505064 110531729 110534463

OGO:	123993448 123998246(abca7) 124011088 124013200 124014229 124019095

ONE:	115109161 115129496 115130742 115133544 115137374 115138075 115145754

SALP:

111952304 111965776 111967529 111971606

SNH:	120030237 120034926 120048072 120048976 120052909 120054032(abca7) 120061998

CCLU:

121534037 121535748 121541916 121554258 121576855(abca7)

ELS:	105007532 105020625 105021086 105029292

SFM:	108925924 108930579 108938700 108938769

PKI:	111842617 111844219 111848707(abca1) 111860314

AANG:

118224515(zgc:172302) 118230978 118231754

LOC:	102683509 102685889(abca7) 102689923(abca1)

PSPA:

121294859 121301158(abca7) 121323314

ARUT:

117401321 117408622 117420799 117428827

PSEX:

120532285(abca1a)

LCM:	102348605(ABCA1) 102348684 102366526(ABCA7)

CMK:	103177714 103188162 103188345

RTP:	109913748(abca1) 109936492

CPLA:

BFO:

BBEL:

CIN:

SCLV:

SPU:	100891819 589328

APLC:

SKO:

ACER:

ALAB:

BBIF:

BVK:

BVAN:

BPYO:

NMEA:

CGLO:

FAS:

DCI:	103506037 103524403

CLEC:

106667941 106668775 106672589

HHAL:

106692476 106692533

NLU:

111044570

FOC:	113201790 113217854

TPAL:

117645999 117648129

SGRE:

126336982

FCD:

110847107

DPX:	DAPPUDRAFT_312055 DAPPUDRAFT_312056

DMK:	116929944 116929945

DPZ:

PVM:

PJA:

HAME:

EAF:	111697087 111700646

LSM:

121119214

PPOI:

119107019

DSV:	119433343 119441948

RSAN:

119387613 119404895

RMP:	119178525 119181195

VDE:	111244063 111245259

VJA:

TUT:

CSCU:

SDM:

CEL:	CELE_F12B6.1(abt-2)

CBR:	CBG_03891(Cbr-abt-2)

BMY:	BM_BM3319(Bma-abt-2)

LOA:	LOAG_18530

HRO:	HELRODRAFT_156842 HELRODRAFT_77531

LGI:	LOTGIDRAFT_212836

PCAN:

BGT:

GAE:

HRF:

HRJ:	124267007 124284663

CRG:	105322394 105334096

MYI:	110442797 110442822

PMAX:

MCAF:

MMER:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_056290

OVI:	T265_13456

EGL:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:	114527058 114536343

XEN:

124445090

HMG:

100214482

TAD:	TRIADDRAFT_10137

AQU:

100642126

OTA:	OT_ostta18g01310

BPG:	Bathy09g00660

MIS:	MICPUN_57369 MICPUN_59198

GLA:	GL50803_0094478

» show all

Reference

PMID:10882340

Authors

Oram JF, Vaughan AM

Title

ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins.

Journal

Curr Opin Lipidol 11:253-60 (2000)
DOI:10.1097/00041433-200006000-00005

Reference

PMID:10092505

Authors

Langmann T, Klucken J, Reil M, Liebisch G, Luciani MF, Chimini G, Kaminski WE, Schmitz G

Title

Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

Journal

Biochem Biophys Res Commun 257:29-33 (1999)
DOI:10.1006/bbrc.1999.0406

Sequence

[hsa:19]

All links

Ontology (3)   
   KEGG BRITE (2)   
   TC (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (3)   
   KEGG DISEASE (3)   
Gene (5345)   
   KEGG GENES (764)   
   KEGG MGENES (937)   
   RefGene (3634)   
   OC (10)   
Literature (2)   
   PubMed (2)   
All databases (5361)   

Download RDF

DBGET integrated database retrieval system