KEGG   ORTHOLOGY: K05653
Entry
K05653                      KO                                     

Name
ABCB2, TAP1
Definition
ATP-binding cassette, subfamily B (MDR/TAP), member 2
Pathway
ko02010  ABC transporters
ko04145  Phagosome
ko04612  Antigen processing and presentation
ko05163  Human cytomegalovirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05340  Primary immunodeficiency
Disease
H00093  Combined immunodeficiency
H00984  Bare lymphocyte syndrome type1
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05168 Herpes simplex virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05163 Human cytomegalovirus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05169 Epstein-Barr virus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
  09163 Immune disease
   05340 Primary immunodeficiency
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB2, 3, 8, 9, 10 subgroups
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Other DBs
TC: 3.A.1.209
Genes
HSA: 6890(TAP1)
PTR: 471978(TAP1)
PPS: 100969222(TAP1)
GGO: 101135419(TAP1)
PON: 100444044(TAP1)
NLE: 100605253(TAP1)
MCC: 717726(TAP1)
MCF: 102142346(TAP1)
CSAB: 103221692(TAP1)
RRO: 104666626(TAP1)
RBB: 108512976(TAP1)
CJC: 100407051(TAP1)
SBQ: 101050206(TAP1)
MMU: 21354(Tap1)
MCAL: 110312383(Tap1)
MPAH: 110335738(Tap1)
RNO: 24811(Tap1)
MUN: 110543126(Tap1)
CGE: 100751458(Tap1)
NGI: 103748644(Tap1)
HGL: 101711399(Tap1)
CCAN: 109686707(Tap1)
OCU: 100349155(TAP1)
TUP: 102488648(TAP1)
CFA: 474866(TAP1)
VVP: 112913865(TAP1)
AML: 100464886(TAP1)
UMR: 103665513(TAP1)
UAH: 113243781(TAP1)
ORO: 101370146(TAP1)
ELK: 111152176
PTG: 102969103(TAP1)
PPAD: 109271409(TAP1)
AJU: 106976125(TAP1)
BTA: 524959(TAP1)
BOM: 102269065(TAP1)
BIU: 109577139(TAP1)
BBUB: 102391940(TAP1)
CHX: 102181173(TAP1)
OAS: 101115580(TAP1)
SSC: 733649(TAP1)
CFR: 102506212(TAP1)
CDK: 105101403(TAP1)
BACU: 103011180(TAP1)
LVE: 103084615(TAP1)
OOR: 101289708(TAP1)
DLE: 111178660(TAP1)
PCAD: 102995173(TAP1)
ECB: 100060845(TAP1)
EAI: 106834612(TAP1)
MYB: 102252020(TAP1)
MYD: 102761514(TAP1)
MNA: 107542669(TAP1)
HAI: 109378146(TAP1)
DRO: 112302332(TAP1)
PALE: 102893312(TAP1)
RAY: 107511995(TAP1)
MJV: 108388306(TAP1)
LAV: 100672952(TAP1)
TMU: 101341807
MDO: 100026750(TAP1)
SHR: 116423203(TAP1)
OAA: 100088116(TAP1)
GGA: 427727(TAP1)
CJO: 107321559(TAP1)
NMEL: 110406673(TAP1)
APLA: 101797680(TAP1)
ACYG: 106029502
LSR: 110481231
FAB: 101809503
PHI: 102109093
PMAJ: 107199186
CCW: 120412065
ETL: 114071915
ACUN: 113490724
AAM: 106492644(TAP1)
CMY: 119567530(TAP1)
CPIC: 101952783(TAP2)
PVT: 110071192(TAP1)
PBI: 103063236(TAP1)
PMUR: 107296739(TAP1)
TSR: 106544595
PMUA: 114592172 114592235(TAP1)
XLA: 100329838(tap1.L) 100335018(tap1b)
XTR: 100494735(tap1) 108648266
NPR: 108788360(TAP1)
DRE: 100333043(tap1)
SRX: 107711531(tap1) 107715579
SGH: 107592117 107592491(tap1)
CCAR: 109056322(tap1)
IPU: 108256340(tap1)
PHYP: 113532964
AMEX: 103042617(tap1)
EEE: 113578824(tap1)
TRU: 101077331
LCO: 104928642
NCC: 104965249
MZE: 101484302(tap1)
ONL: 100701175(tap1)
OLA: 101162709(tap1)
XMA: 102217160(tap1)
XCO: 114141733(tap1)
PRET: 103477852(tap1)
CVG: 107082986
NFU: 107379160
KMR: 108245991(tap1)
ALIM: 106523077(tap1)
AOCE: 111577918
CSEM: 103388956
POV: 109647062
LCF: 108899590
SDU: 111222621(tap1)
SLAL: 111655648(tap1)
HCQ: 109521010(tap1)
BPEC: 110171064
MALB: 109965574(tap1)
SASA: 100136585(tap1)
OTW: 112222999(tap1)
ELS: 105021865
PKI: 111838464
LCM: 102361710(TAP1)
CMK: 103173390
 » show all
Reference
  Authors
Xu M, Li L, Liu Z, Jiao Z, Xu P, Kong X, Huang H, Zhang Y
  Title
ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance.
  Journal
Cancer Lett 333:152-8 (2013)
DOI:10.1016/j.canlet.2013.01.002
  Sequence
[hsa:6890]
Reference
PMID:2259383
  Authors
Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, Kelly A
  Title
Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters.
  Journal
Nature 348:741-4 (1990)
DOI:10.1038/348741a0
  Sequence
[hsa:6890]

KEGG   ORTHOLOGY: K05654
Entry
K05654                      KO                                     

Name
ABCB3, TAP2
Definition
ATP-binding cassette, subfamily B (MDR/TAP), member 3
Pathway
ko02010  ABC transporters
ko04145  Phagosome
ko04612  Antigen processing and presentation
ko05163  Human cytomegalovirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05340  Primary immunodeficiency
Disease
H00093  Combined immunodeficiency
H00984  Bare lymphocyte syndrome type1
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
   05168 Herpes simplex virus 1 infection
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
   05163 Human cytomegalovirus infection
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
   05169 Epstein-Barr virus infection
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
  09163 Immune disease
   05340 Primary immunodeficiency
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB2, 3, 8, 9, 10 subgroups
    K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
Other DBs
TC: 3.A.1.209
Genes
HSA: 6891(TAP2)
PTR: 746399(TAP2)
PPS: 100969573(TAP2)
GGO: 101135772(TAP2)
PON: 100444404(TAP2)
NLE: 100604022(TAP2)
MCC: 717742(TAP2)
MCF: 102143391(TAP2)
CSAB: 103221694(TAP2)
RRO: 104666628(TAP2)
RBB: 108512981(TAP2)
CJC: 100406316(TAP2)
SBQ: 101052015(TAP2)
MMU: 21355(Tap2)
MCAL: 110312451(Tap2)
MPAH: 110335586(Tap2)
RNO: 24812(Tap2)
MUN: 110543246(Tap2)
CGE: 100752033(Tap2)
NGI: 103748319(Tap2)
HGL: 101703007(Tap2)
CCAN: 109686711(Tap2)
OCU: 100351666(TAP2)
TUP: 102484450(TAP2)
CFA: 474864(TAP2)
VVP: 112913862(TAP2)
AML: 100478040(TAP2)
UMR: 103665515(TAP2)
UAH: 113243780(TAP2)
ORO: 101369846(TAP2)
ELK: 111152449
PTG: 102958303(TAP2)
PPAD: 109271411(TAP2)
AJU: 106976128(TAP2)
BTA: 281586(TAP2) 618733
BOM: 102283284(TAP2)
BBUB: 102391047(TAP2)
CHX: 102180638(TAP2)
OAS: 101109491(TAP2)
SSC: 733650(TAP2)
CFR: 102519383(TAP2)
CDK: 105101406(TAP2)
BACU: 103012059(TAP2)
LVE: 103072764(TAP2)
OOR: 101290371(TAP2)
DLE: 111178659(TAP2)
PCAD: 102995730(TAP2)
ECB: 100052423(TAP2)
EAI: 106834615(TAP2)
MYB: 102251714(TAP2)
MYD: 102768370(TAP2)
MNA: 107542666(TAP2)
HAI: 109378144(TAP2)
DRO: 112302216(TAP2)
PALE: 102894050(TAP2)
RAY: 107511996(TAP2)
MJV: 108388307(TAP2) 108408874
LAV: 104845430(TAP2)
TMU: 101342308
SHR: 100926063(TAP2)
PCW: 110199320(TAP2) 110199417
OAA: 100529066(TAP2)
GGA: 427728(TAP2)
CJO: 107321558(TAP2)
NMEL: 110406669(TAP2)
APLA: 101797091(TAP2)
ACYG: 106029503(TAP2)
TGU: 115492664
LSR: 110481230
SCAN: 103825036
GFR: 102039635
FAB: 101809296
PHI: 102108912
PMAJ: 107199185
CCAE: 111936803
CCW: 120412070
CMY: 102930546(TAP2)
CPIC: 101953351(TAP2)
ACS: 100559367(tap2)
PVT: 110070640 110071036(TAP2)
PBI: 103056839(TAP2)
TSR: 106539698
XLA: 398090 443560(tap2.L)
XTR: 100489020(tap2) 116406716
NPR: 108788391(TAP2)
DRE: 368771(tap2a) 556826(si:dkey-57h18.2)
SRX: 107727316
AMEX: 103036712
OLA: 101165513 101166481(abcb3)
KMR: 108242643(tap2a) 108250652(tap2t)
SASA: 100136919(tap2a1) 100136924(tap2b) 100195045(abcb3) 106579291
SFM: 108930284
LCM: 102358508(TAP2)
 » show all
Reference
  Authors
Leonhardt RM, Abrahimi P, Mitchell SM, Cresswell P
  Title
Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization.
  Journal
J Immunol 192:2480-94 (2014)
DOI:10.4049/jimmunol.1302637
  Sequence
[hsa:6891]
Reference
PMID:1453454
  Authors
Beck S, Kelly A, Radley E, Khurshid F, Alderton RP, Trowsdale J
  Title
DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing.
  Journal
J Mol Biol 228:433-41 (1992)
DOI:10.1016/0022-2836(92)90832-5
  Sequence
[hsa:6891]

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