KEGG ORTHOLOGY: K05684

ORTHOLOGY: K05684

Entry

K05684                      KO

Symbol

ABCG8

Name

ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)

Pathway

map02010

ABC transporters

map04975

Fat digestion and absorption

map04976

Bile secretion

map04979

Cholesterol metabolism

Disease

H00152

Sitosterolemia

H01213

Gallbladder disease

H01740

Macrothrombocytopenia

H02505

Atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
   04975 Fat digestion and absorption
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
   04979 Cholesterol metabolism
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
Transporters [BR:ko02000]
ABC transporters, eukaryotic type
  ABCG (White) subfamily
   ABCG5, 8 subgroups
    K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)

Other DBs

TC:

3.A.1.204

Genes

HSA:	64241(ABCG8)

PTR:	470363(ABCG8)

PPS:	100968285(ABCG8)

GGO:	101129108(ABCG8)

PON:	100445033(ABCG8)

NLE:	100601594(ABCG8)

HMH:	116484267(ABCG8)

MCC:	713676(ABCG8)

MCF:	102142368(ABCG8)

MTHB:

126933361

MNI:	105464936(ABCG8)

CSAB:

103220381(ABCG8)

CATY:

105590576 105597078(ABCG8)

PANU:

101011017(ABCG8)

TGE:	112604944(ABCG8)

MLEU:

105538356(ABCG8)

RRO:	104677525(ABCG8)

RBB:	108522512(ABCG8)

TFN:	117062385(ABCG8)

PTEH:

111528870(ABCG8)

CANG:

105507525(ABCG8)

CJC:	100402530(ABCG8)

SBQ:	101031766(ABCG8)

CIMI:

108315493(ABCG8)

CSYR:

103260470(ABCG8)

MMUR:

105866808(ABCG8)

LCAT:

123636861(ABCG8)

PCOQ:

105818010(ABCG8)

OGA:	100953238(ABCG8)

MMU:	67470(Abcg8)

MCAL:

110283681(Abcg8)

MPAH:

110335675(Abcg8)

RNO:	155192(Abcg8)

MCOC:

116079695(Abcg8)

ANU:	117717154(Abcg8)

MUN:	110558061(Abcg8)

CGE:	100765601(Abcg8)

MAUA:

101838417(Abcg8)

PROB:

127214904(Abcg8)

PLEU:

114709600(Abcg8)

MORG:

121432959(Abcg8)

MFOT:

126504079

AAMP:

119808011(Abcg8)

NGI:	103725768(Abcg8)

HGL:	101723060(Abcg8)

CPOC:

100725586(Abcg8)

CCAN:

109700491(Abcg8)

DORD:

105986835(Abcg8)

DSP:	122104567(Abcg8)

NCAR:

124963655

OCU:

100350554

OPI:	101517555(ABCG8)

TUP:	102471620(ABCG8)

GVR:	103607626(ABCG8)

CFA:	474571(ABCG8)

CLUD:

112671228(ABCG8)

VVP:	112915330(ABCG8)

VLG:	121490779(ABCG8)

AML:	100466630(ABCG8)

UMR:	103671214(ABCG8)

UAH:	113246320(ABCG8)

UAR:	123776051(ABCG8)

ELK:

111155907

LLV:

125108733

MPUF:

101671730(ABCG8)

NVS:	122915662(ABCG8)

ORO:	101383671(ABCG8)

EJU:	114209833(ABCG8)

ZCA:	113937720(ABCG8)

MLX:	118007574(ABCG8)

NSU:	110590425(ABCG8)

LWW:	102742441(ABCG8)

FCA:	101099288(ABCG8)

PYU:	121016362(ABCG8)

PBG:	122496781(ABCG8)

LRUF:

124504254

PTG:	102952620(ABCG8)

PPAD:

109276477(ABCG8)

PUC:

125936221

AJU:	106976965(ABCG8)

HHV:	120232025(ABCG8)

BTA:	508829(ABCG8)

BOM:	102286592(ABCG8)

BIU:	109566029(ABCG8)

BBUB:

102409829(ABCG8)

BBIS:

104990300(ABCG8)

CHX:	102189408(ABCG8)

OAS:	101113666(ABCG8)

ODA:	120851715(ABCG8)

CCAD:

122441624(ABCG8)

SSC:	100048963(ABCG8)

CFR:	102504262(ABCG8)

CBAI:

105079013(ABCG8)

CDK:	105103556(ABCG8)

VPC:	102537411(ABCG8)

BACU:

103011013(ABCG8)

LVE:	103081330(ABCG8)

OOR:	101279618(ABCG8)

DLE:	111174723(ABCG8)

PCAD:

102982902(ABCG8)

PSIU:

116764463(ABCG8)

NASI:

112405224(ABCG8)

ECB:	100069071(ABCG8)

EPZ:	103547785(ABCG8)

EAI:	106826307(ABCG8)

MYB:	102259291(ABCG8)

MYD:	102763481(ABCG8)

MMYO:

118669051(ABCG8)

MLF:	102440954(ABCG8)

MNA:	107530337(ABCG8)

PKL:	118717293(ABCG8)

HAI:	109385556(ABCG8)

DRO:	112298158(ABCG8)

SHON:

119001275(ABCG8)

AJM:	119061523(ABCG8)

PDIC:

114500098(ABCG8)

PHAS:

123811914(ABCG8)

MMF:	118630984(ABCG8)

RFQ:	117032909(ABCG8)

PALE:

102895394(ABCG8)

PGIG:

120621707(ABCG8)

PVP:	105292977(ABCG8)

RAY:	107509456(ABCG8)

MJV:	108384106(ABCG8)

TOD:	119259963(ABCG8)

SARA:

101557820(ABCG8)

LAV:	100671872(ABCG8)

TMU:

101356768

ETF:	101646124(ABCG8)

DNM:	101437019(ABCG8)

MDO:	100033372(ABCG8)

GAS:	123233325(ABCG8)

SHR:	100926618(ABCG8)

AFZ:

127548035

PCW:	110218557(ABCG8)

OAA:	100080045(ABCG8)

GGA:	421402(ABCG8)

PCOC:

116232999(ABCG8)

MGP:	100547312(ABCG8)

CJO:	107311175(ABCG8)

NMEL:

110396685(ABCG8)

APLA:

101799966(ABCG8)

ACYG:

106031481(ABCG8)

AFUL:

116487183(ABCG8)

TGU:	100229585(ABCG8)

LSR:	110468473(ABCG8)

SCAN:

103817092(ABCG8)

PMOA:

120497020(ABCG8)

OTC:	121340681(ABCG8)

PRUF:

121358686(ABCG8)

GFR:	102035432(ABCG8)

FAB:	101811830(ABCG8)

PHI:	102109295(ABCG8)

PMAJ:

107202225(ABCG8)

CCAE:

111926134(ABCG8)

CCW:	104685679(ABCG8)

CBRC:

103622720(ABCG8)

ETL:	114067873(ABCG8)

ZAB:	102073693(ABCG8)

ACHL:

103802450(ABCG8)

SVG:	106857218(ABCG8)

FPG:	101918567(ABCG8)

FCH:	102060238(ABCG8)

CLV:	102085704(ABCG8)

EGZ:	104128751(ABCG8)

NNI:	104019693(ABCG8)

PLET:

104623026(ABCG8)

PCRI:

104034345(ABCG8)

PCAO:

104045735(ABCG8)

ACUN:

113477934(ABCG8)

TALA:

104362864(ABCG8)

PADL:

103918087(ABCG8)

AFOR:

103898184(ABCG8)

ACHC:

115349804(ABCG8)

HALD:

104321355(ABCG8)

HLE:	104837387(ABCG8)

AGEN:

126052784

GCL:

127014926

CCRI:

104164827(ABCG8)

CSTI:

104556208(ABCG8)

EHS:	104513356(ABCG8)

CMAC:

104475766(ABCG8)

MUI:	104545780(ABCG8)

FGA:

104084413

GSTE:

104259960(ABCG8)

LDI:	104346184(ABCG8)

MNB:	103773579(ABCG8)

OHA:	104327930(ABCG8)

NNT:	104406176(ABCG8)

SHAB:

115613584(ABCG8)

DPUB:

104303419(ABCG8)

PGUU:

104463856(ABCG8)

ACAR:

104528187(ABCG8)

CPEA:

104395257(ABCG8)

AVIT:

104274732(ABCG8)

CVF:	104282537(ABCG8)

CUCA:

104058006(ABCG8)

TEO:	104373326(ABCG8)

BRHI:

104490618(ABCG8)

AAM:	106490333(ABCG8)

AROW:

112969200(ABCG8)

NPD:	112953224(ABCG8)

TGT:	104576034(ABCG8)

DNE:	112997316(ABCG8)

SCAM:

104140340(ABCG8)

ASN:	102380988(ABCG8)

AMJ:	102570120(ABCG8)

CPOO:

109319660(ABCG8)

GGN:	109296783(ABCG8)

PSS:	102452045(ABCG8)

CPIC:

101932157(ABCG8)

TST:	117874382(ABCG8)

CABI:

116821559(ABCG8)

MRV:	120401951(ABCG8)

ACS:	100553787(abcg8)

PVT:	110082725(ABCG8)

SUND:

121930553(ABCG8)

PMUA:

114594734(ABCG8)

ZVI:	118083108(ABCG8)

GJA:	107109508(ABCG8)

STOW:

125437347(ABCG8)

XLA:	108717731(abcg8.S)

XTR:	100498405(abcg8)

NPR:	108793704(ABCG8)

RTEM:

120937960(ABCG8)

BBUF:

120999314(ABCG8)

BGAR:

122935514(ABCG8)

DRE:	100136850(abcg8)

SRX:	107747584(abcg8)

SANH:

107666472

SGH:	107587837(abcg8)

CCAR:

109065452 109100986

CAUA:

113112801(abcg8)

CGIB:

128026314

PPRM:

120479374(abcg8)

MAMB:

125276760(abcg8)

CIDE:

127525450

MASI:

127412127 127413663

IPU:	108263667(abcg8)

PHYP:

113543832(abcg8)

SMEO:

124394312(abcg8)

TFD:	113644954(abcg8)

AMEX:

103023216(abcg8)

EEE:	113578366(abcg8)

TRU:	101061176(abcg8)

TNG:	GSTEN00014343G001

LCO:	104928439(abcg8)

NCC:	104954354(abcg8)

CGOB:

115020224(abcg8)

ELY:	117248404(abcg8)

EFO:	125903483(abcg8)

PLEP:

121954768(abcg8)

SLUC:

116056662(abcg8)

ECRA:

117960681(abcg8)

ESP:	116704919(abcg8)

PFLV:

114571768(abcg8)

GAT:	120820677(abcg8)

PPUG:

119213755(abcg8)

MSAM:

119917001(abcg8)

CUD:	121510733(abcg8)

ALAT:

119033440(abcg8)

MZE:	101467554(abcg8)

ONL:	100694298(abcg8)

OAU:	116325770(abcg8)

OLA:	101158473(abcg8)

OML:	112161486(abcg8)

XMA:	102236161(abcg8)

XCO:	114138223(abcg8)

XHE:	116713554(abcg8)

PRET:

103476401(abcg8)

PFOR:

103137449(abcg8)

PLAI:

106953427(abcg8)

PMEI:

106909562(abcg8)

GAF:	122842071(abcg8)

CVG:	107086910(abcg8)

CTUL:

119793143(abcg8)

GMU:	124858615(abcg8)

NFU:	107375838(abcg8)

KMR:	108245090(abcg8)

ALIM:

106534501(abcg8)

NWH:	119412522(abcg8)

AOCE:

111564964(abcg8)

MCEP:

125018568(abcg8)

CSEM:

103387122(abcg8)

POV:	109632262(abcg8)

SSEN:

122778323 122782110(abcg8)

HHIP:

117775567(abcg8)

HSP:	118119100(abcg8)

LCF:

108897406

SDU:	111235340(abcg8)

SLAL:

111645286(abcg8)

XGL:	120796839(abcg8)

HCQ:	109510249(abcg8)

SSCV:

125978886

BPEC:

110157090(abcg8)

MALB:

109958721(abcg8)

BSPL:

114842017(abcg8)

SASA:

106589695(abcg8)

STRU:

115201519(abcg8)

OTW:	112224571(abcg8)

OMY:	110499297(abcg8)

OGO:	124040286(abcg8)

ONE:	115144351(abcg8)

SALP:

111968036(abcg8)

SNH:	120029967(abcg8)

CCLU:

121547652(abcg8)

ELS:	105021238(abcg8)

SFM:	108942670(abcg8)

PKI:	111839948(abcg8)

AANG:

118218415(abcg8)

LOC:	102690434(abcg8)

PSPA:

121316353(abcg8)

ARUT:

117402743(abcg8)

PSEX:

120516486(abcg8)

LCM:	102351772(ABCG8)

CMK:	103180802(abcg8)

RTP:	109936058(abcg8)

CPLA:

122552726(abcg8)

DME:	Dmel_CG31121(CG31121)

DER:

6554153

DSE:

6607829

DSI:	Dsimw501_GD18254(Dsim_GD18254)

DYA:	Dyak_GE10759

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23153

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

RZE:

MDE:

SCAC:

LCQ:

LSQ:

HIS:

AGA:	AgaP_AGAP002050

ACOZ:

AARA:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ005341

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_210111

BANY:

NIQ:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

CFEL:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:	103507175 103524018

CLEC:

106663218

HHAL:

106681656

NLU:	111044260 120356566

PHU:	Phum_PHUM576380

FOC:

TPAL:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_258299

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

PTRU:

ESN:

HAZT:

EAF:

LSM:

PPOI:

119098050 119111367 119111368

ISC:	IscW_ISCW018080

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

SDM:

LGI:	LOTGIDRAFT_128489 LOTGIDRAFT_128491

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MCAF:

MMER:

DPOL:

LAK:	106159069 106168329

DPP:	DICPUDRAFT_27275(ABCG27)

DFA:

DFA_04631

ACAN:

ACA1_088810

» show all

Reference

PMID:11099417

Authors

Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH

Title

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

Journal

Science 290:1771-5 (2000)
DOI:10.1126/science.290.5497.1771

Sequence

[hsa:64241]

All links

Ontology (3)   
   KEGG BRITE (2)   
   TC (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (4)   
   KEGG DISEASE (4)   
Gene (682)   
   KEGG GENES (494)   
   KEGG MGENES (46)   
   RefGene (139)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (698)   

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