KEGG   ORTHOLOGY: K05703
Entry
K05703                      KO                                     

Name
FYN
Definition
tyrosine-protein kinase Fyn [EC:2.7.10.2]
Pathway
ko04071  Sphingolipid signaling pathway
ko04072  Phospholipase D signaling pathway
ko04360  Axon guidance
ko04380  Osteoclast differentiation
ko04510  Focal adhesion
ko04520  Adherens junction
ko04611  Platelet activation
ko04650  Natural killer cell mediated cytotoxicity
ko04660  T cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04725  Cholinergic synapse
ko05020  Prion disease
ko05130  Pathogenic Escherichia coli infection
ko05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K05703  FYN; tyrosine-protein kinase Fyn
   04071 Sphingolipid signaling pathway
    K05703  FYN; tyrosine-protein kinase Fyn
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05703  FYN; tyrosine-protein kinase Fyn
   04520 Adherens junction
    K05703  FYN; tyrosine-protein kinase Fyn
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05703  FYN; tyrosine-protein kinase Fyn
   04650 Natural killer cell mediated cytotoxicity
    K05703  FYN; tyrosine-protein kinase Fyn
   04660 T cell receptor signaling pathway
    K05703  FYN; tyrosine-protein kinase Fyn
   04664 Fc epsilon RI signaling pathway
    K05703  FYN; tyrosine-protein kinase Fyn
  09156 Nervous system
   04725 Cholinergic synapse
    K05703  FYN; tyrosine-protein kinase Fyn
  09158 Development and regeneration
   04360 Axon guidance
    K05703  FYN; tyrosine-protein kinase Fyn
   04380 Osteoclast differentiation
    K05703  FYN; tyrosine-protein kinase Fyn
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05703  FYN; tyrosine-protein kinase Fyn
  09164 Neurodegenerative disease
   05020 Prion disease
    K05703  FYN; tyrosine-protein kinase Fyn
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K05703  FYN; tyrosine-protein kinase Fyn
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05703  FYN; tyrosine-protein kinase Fyn
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05703  FYN; tyrosine-protein kinase Fyn
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05703  FYN; tyrosine-protein kinase Fyn
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  SRC family
   K05703  FYN; tyrosine-protein kinase Fyn
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    K05703  FYN; tyrosine-protein kinase Fyn
 Endocytosis
  Lipid raft mediated endocytosis
   Flotillin-dependent endocytosis
    K05703  FYN; tyrosine-protein kinase Fyn
Other DBs
GO: 0004715
Genes
HSA: 2534(FYN)
PTR: 462944(FYN)
PPS: 100971932(FYN)
GGO: 101143006(FYN)
PON: 100439712(FYN)
NLE: 100585303(FYN)
MCC: 574214(FYN)
MCF: 102126878(FYN)
CSAB: 103240563(FYN)
RRO: 104668854(FYN)
RBB: 108512073(FYN)
CJC: 100391434(FYN)
SBQ: 101051746(FYN)
MMU: 14360(Fyn)
MCAL: 110302997(Fyn)
MPAH: 110326389(Fyn)
RNO: 25150(Fyn)
MUN: 110561016(Fyn)
CGE: 100772355(Fyn)
NGI: 103749533(Fyn)
HGL: 101721279(Fyn)
CCAN: 109695356(Fyn)
OCU: 100339741(FYN)
TUP: 102498676(FYN)
CFA: 475032(FYN)
VVP: 112925186(FYN)
AML: 100470931(FYN)
UMR: 103676988(FYN)
UAH: 113264721(FYN)
ORO: 101362244(FYN)
ELK: 111158275
FCA: 101085720(FYN)
PTG: 102956260(FYN)
PPAD: 109263555(FYN)
AJU: 106968910(FYN)
BTA: 527263(FYN)
BOM: 102284015(FYN)
BIU: 109563811(FYN)
BBUB: 102416287(FYN)
CHX: 102179673(FYN)
OAS: 101109363(FYN)
SSC: 791125(FYN)
CFR: 102506492(FYN)
CDK: 105099211(FYN)
BACU: 103012275(FYN)
LVE: 103071829(FYN)
OOR: 101279266(FYN)
DLE: 111164732(FYN)
PCAD: 102974010(FYN)
ECB: 102149085(FYN)
EPZ: 103547543(FYN)
EAI: 106847048(FYN)
MYB: 102242533(FYN)
MYD: 102751410(FYN)
MNA: 107540684(FYN)
HAI: 109384758(FYN)
DRO: 112297021(FYN)
PALE: 102896849(FYN)
RAY: 107506307(FYN)
MJV: 108396080(FYN)
LAV: 100675535(FYN)
TMU: 101340362
MDO: 100022459(FYN)
SHR: 100923088(FYN)
PCW: 110222880(FYN)
OAA: 100073798(FYN)
GGA: 396294(FYN)
MGP: 100543914
CJO: 107311849(FYN)
NMEL: 110397033(FYN)
APLA: 101799525(FYN)
ACYG: 106032576(FYN)
TGU: 100228220(FYN)
LSR: 110484642(FYN)
SCAN: 103818548(FYN)
GFR: 102037765(FYN)
FAB: 101807629(FYN)
PHI: 102103534(FYN)
PMAJ: 107202142(FYN)
CCAE: 111927157(FYN)
CCW: 104691303(FYN)
ETL: 114062026(FYN)
FPG: 101924310(FYN)
FCH: 102057542(FYN)
CLV: 102095466(FYN)
EGZ: 104131981(FYN)
NNI: 104011133(FYN)
ACUN: 113477834(FYN)
PADL: 103918980(FYN)
AAM: 106489691(FYN)
ASN: 102384418(FYN)
AMJ: 102574913(FYN)
PSS: 102464071(FYN)
CMY: 102935370(FYN)
CPIC: 101949716(FYN)
ACS: 100559709(fyn)
PVT: 110085313(FYN)
PBI: 103062202(FYN)
PMUR: 107287161(FYN)
TSR: 106540113(FYN)
PMUA: 114594054(FYN)
GJA: 107118444(FYN)
XLA: 373609(fyn.L) 379812(fyn.S)
XTR: 100488004(fyn)
NPR: 108790091(FYN)
DRE: 373872(fyna) 574422(fynb)
SRX: 107750405 107751750 107755004 107755790
SANH: 107670246(fyn) 107680776 107693124 107704353
SGH: 107548254 107564973 107565451 107583469
CCAR: 109050311 109107918 109113279
IPU: 108255503 108270342(fyna)
PHYP: 113525201(fyn) 113533722
AMEX: 103026055(fyn) 103043249
EEE: 113586228 113590638
TRU: 101063191 101070253(fyn)
TNG: GSTEN00010460G001 GSTEN00031972G001 GSTEN00031974G001
LCO: 104922928(fyn) 104931606
NCC: 104960495(fyn)
MZE: 101474799 101479859(fyn)
ONL: 100690757(fyn) 100691175
OLA: 101157019 101167011
XMA: 102233390 102237794
XCO: 114134301 114158470
PRET: 103458010 103458742
CVG: 107092365(fyn) 107096191
NFU: 107392150 107396024(fyn)
KMR: 108236545 108248899(fynb)
ALIM: 106518449 106529781
AOCE: 111563357(fyn) 111573260
CSEM: 103378673 103380632(fyn)
POV: 109632533(fyn) 109636463
LCF: 108875026 108899306(fyn)
SDU: 111225278 111235770(fyn)
SLAL: 111651009 111672913(fyn)
HCQ: 109517462 109524890
BPEC: 110153632
MALB: 109968046 109968087(fyn)
SASA: 100306819(fyn) 106571317
OTW: 112217528 112250060
SALP: 111954280 111972516
ELS: 105017971(fyn)
SFM: 108921798 108929301(fyn)
PKI: 111843036(fyn) 111857866
LCM: 102354666(FYN)
CMK: 103178951(fyn)
RTP: 109912754
BFO: 118403854
NVL: 108561389
OBI: 106875007
LAK: 106171164
SMM: Smp_136300 Smp_172200
SHX: MS3_05835
OVI: T265_07913
EGL: EGR_09507
AQU: 100631421 100633614 100635873 100636000 100638702 100640218 109584853 109584989
 » show all
Reference
PMID:7822789
  Authors
Rigley K, Slocombe P, Proudfoot K, Wahid S, Mandair K, Bebbington C
  Title
Human p59fyn(T) regulates OKT3-induced calcium influx by a mechanism distinct from PIP2 hydrolysis in Jurkat T cells.
  Journal
J Immunol 154:1136-45 (1995)
  Sequence
[hsa:2534]

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Pathway (28)   
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Gene (520)   
   KEGG GENES (207)   
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Literature (1)   
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