KEGG   ORTHOLOGY: K05726
Entry
K05726                      KO                                     
Symbol
BCAR1, CAS
Name
breast cancer anti-estrogen resistance 1
Pathway
map04015  Rap1 signaling pathway
map04062  Chemokine signaling pathway
map04148  Efferocytosis
map04510  Focal adhesion
map04670  Leukocyte transendothelial migration
map04810  Regulation of actin cytoskeleton
map04935  Growth hormone synthesis, secretion and action
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05135  Yersinia infection
map05163  Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   04062 Chemokine signaling pathway
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   05135 Yersinia infection
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   05100 Bacterial invasion of epithelial cells
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
Genes
HSA: 9564(BCAR1)
PTR: 454246(BCAR1)
PPS: 100980143(BCAR1)
GGO: 101132653(BCAR1)
PON: 103889518(BCAR1)
PPYG: 129015476(BCAR1)
NLE: 100598535(BCAR1)
HMH: 116470814(BCAR1)
SSYN: 129493388(BCAR1)
MCC: 713965(BCAR1)
MCF: 102114845(BCAR1)
MTHB: 126943713
MNI: 105491272(BCAR1)
CSAB: 103233309(BCAR1)
CATY: 105572979(BCAR1)
PANU: 101013590(BCAR1)
TGE: 112613778(BCAR1)
MLEU: 105537242(BCAR1)
RRO: 104677838(BCAR1)
RBB: 108527422(BCAR1)
TFN: 117088057(BCAR1)
PTEH: 111536154(BCAR1)
CANG: 105514570(BCAR1)
CJC: 100391559(BCAR1)
SBQ: 101041293(BCAR1)
CIMI: 108305732(BCAR1)
ANAN: 105706748(BCAR1)
CSYR: 103251606(BCAR1)
MMUR: 105875451(BCAR1)
LCAT: 123625428(BCAR1)
PCOQ: 105808008(BCAR1)
OGA: 100955552(BCAR1)
MMU: 12927(Bcar1)
MCAL: 110299902(Bcar1)
MPAH: 110337447(Bcar1)
RNO: 25414(Bcar1)
MCOC: 116070207(Bcar1)
ANU: 117723039(Bcar1)
MUN: 110554744(Bcar1)
CGE: 100768861(Bcar1)
MAUA: 101826097(Bcar1)
PROB: 127234668(Bcar1)
PLEU: 114709099(Bcar1)
MORG: 121446990(Bcar1)
MFOT: 126502806
AAMP: 119802091(Bcar1)
NGI: 103725688(Bcar1)
HGL: 101709701(Bcar1)
CPOC: 100713475(Bcar1)
CCAN: 109684025(Bcar1)
DORD: 105983092(Bcar1)
DSP: 122126159(Bcar1)
PLOP: 125358177(Bcar1)
NCAR: 124967218
MMMA: 107150899(Bcar1)
OCU: 100350323
OPI: 101522546(BCAR1)
TUP: 102488824(BCAR1)
CFA: 479648(BCAR1)
CLUD: 112646654(BCAR1)
VVP: 112915672(BCAR1)
VLG: 121499705(BCAR1)
NPO: 129497226(BCAR1)
AML: 100479448(BCAR1)
UMR: 103662115(BCAR1)
UAH: 113252495(BCAR1)
UAR: 123791314(BCAR1)
ELK: 111152853
LLV: 125089499
MPUF: 101691130(BCAR1)
MNP: 132005689(BCAR1)
MLK: 131817944(BCAR1)
NVS: 122911232(BCAR1)
ORO: 101364349(BCAR1)
EJU: 114202711(BCAR1)
ZCA: 113936040(BCAR1)
MLX: 118023562(BCAR1)
NSU: 110591950(BCAR1)
LWW: 102726881
FCA: 101096625(BCAR1)
PYU: 121009797(BCAR1)
PCOO: 112857231(BCAR1)
PBG: 122494471(BCAR1)
PVIV: 125153269(BCAR1)
LRUF: 124511865
PTG: 102961947(BCAR1)
PPAD: 109245694(BCAR1)
PUC: 125916426
AJU: 106989704
HHV: 120248194(BCAR1)
BTA: 527550(BCAR1)
BOM: 102286652(BCAR1)
BIU: 109572528(BCAR1)
BBUB: 102391781(BCAR1)
BBIS: 104996481(BCAR1)
CHX: 102176451(BCAR1)
OAS: 101117693(BCAR1)
BTAX: 128062963(BCAR1)
ODA: 120872852(BCAR1)
CCAD: 122421110(BCAR1)
MBEZ: 129547261(BCAR1)
SSC: 100621541(BCAR1)
CFR: 102522119(BCAR1)
CBAI: 105078652(BCAR1)
CDK: 105085072(BCAR1)
VPC: 102533924(BCAR1)
BACU: 102999909(BCAR1)
BMUS: 118885184(BCAR1)
LVE: 103077564(BCAR1)
OOR: 101286283(BCAR1)
DLE: 111179506(BCAR1)
PCAD: 102974736(BCAR1)
PSIU: 116744074(BCAR1)
NASI: 112393343(BCAR1)
ECB: 100068908(BCAR1)
EPZ: 103553038(BCAR1)
EAI: 106835699(BCAR1)
MYB: 102256265(BCAR1)
MYD: 102751761(BCAR1)
MMYO: 118674128(BCAR1)
MLF: 102431239(BCAR1)
MDT: 132217325(BCAR1)
PKL: 118720505(BCAR1)
EFUS: 103284373(BCAR1)
MNA: 107524660(BCAR1)
DRO: 112300743(BCAR1)
SHON: 118999214(BCAR1)
AJM: 119048924(BCAR1)
PDIC: 114488127(BCAR1)
PHAS: 123805863(BCAR1)
MMF: 118639462(BCAR1)
PPAM: 129075188(BCAR1)
HAI: 109384807(BCAR1)
RFQ: 117034639(BCAR1)
PALE: 102897097(BCAR1)
PGIG: 120617366(BCAR1)
PVP: 105305354(BCAR1)
RAY: 107502656(BCAR1)
MJV: 108396170(BCAR1)
TOD: 119249084(BCAR1)
SARA: 101557104(BCAR1)
SETR: 126027351(BCAR1)
LAV: 100675124(BCAR1)
TMU: 101346861
ETF: 101642973(BCAR1)
DNM: 101444214(BCAR1)
GAS: 123255869
AFZ: 127547693
PCW: 110192462(BCAR1)
TVP: 118843761(BCAR1)
OAA: 100085802(BCAR1)
GGA: 415691(BCAR1)
PCOC: 116243714(BCAR1)
MGP: 100543321 104913032(BCAR1)
CJO: 107319194(BCAR1)
TPAI: 128081724(BCAR1)
LMUT: 125699064(BCAR1)
NMEL: 110404454(BCAR1)
APLA: 101792603(BCAR1)
ACYG: 106043124(BCAR1)
CATA: 118246530(BCAR1)
AFUL: 116494114(BCAR1)
TGU: 100231478(BCAR1)
LSR: 110472998(BCAR1)
SCAN: 103816661(BCAR1)
PMOA: 120507998(BCAR1)
OTC: 121333870(BCAR1)
PRUF: 121348806(BCAR1)
GFR: 102041223(BCAR1)
FAB: 101822200(BCAR1)
OMA: 130257874(BCAR1)
PHI: 102099890(BCAR1)
PMAJ: 107209875(BCAR1)
CCAE: 111934540(BCAR1)
CCW: 104687562(BCAR1)
CBRC: 103620292(BCAR1)
ETL: 114069815(BCAR1)
ZAB: 102072898(BCAR1)
ZLE: 135452676(BCAR1)
ACHL: 103798443
SVG: 106855836(BCAR1)
MMEA: 130572693(BCAR1)
HRT: 120757726(BCAR1)
SATI: 136366595(BCAR1)
FPG: 101919872(BCAR1)
FCH: 102047594(BCAR1)
NNT: 104408939
SHAB: 115601091(BCAR1) 115619013
ACUN: 113484549(BCAR1)
TALA: 116965967(BCAR1)
ACHC: 115345831(BCAR1)
HLE: 104842161(BCAR1)
AGEN: 126041069
GCL: 127021089
LDI: 104353499(BCAR1)
DPUB: 104299017(BCAR1)
BRHI: 104498303(BCAR1)
EGZ: 104130282(BCAR1)
NNI: 104016382(BCAR1)
PCRI: 104036011(BCAR1)
AFOR: 103896885(BCAR1)
CLV: 102090770(BCAR1)
PLET: 104617596(BCAR1)
CUCA: 104055946(BCAR1)
TEO: 104380097(BCAR1)
CPEA: 104386318(BCAR1)
CVF: 104293456(BCAR1)
RTD: 128909361(BCAR1)
AAM: 106490061(BCAR1)
AROW: 112978255(BCAR1)
NPD: 112943196(BCAR1)
TGT: 104573906(BCAR1)
DNE: 112987467(BCAR1)
SCAM: 104149530
ASN: 102387422(BCAR1)
AMJ: 102565268(BCAR1)
CPOO: 109310330(BCAR1)
GGN: 109289657(BCAR1)
CMY: 102938416(BCAR1)
CCAY: 125620869(BCAR1)
DCC: 119841327(BCAR1)
CPIC: 101937536(BCAR1)
CABI: 116831920(BCAR1)
MRV: 120384673(BCAR1)
ASAO: 132782949(BCAR1)
PVT: 110081315(BCAR1)
SUND: 121937506(BCAR1)
PBI: 103054416(BCAR1)
PMUR: 107287376(BCAR1)
CTIG: 120312673(BCAR1)
TSR: 106539030(BCAR1)
PGUT: 117670420(BCAR1)
APRI: 131184042(BCAR1)
PTEX: 113445305(BCAR1)
NSS: 113420290(BCAR1)
VKO: 123025466(BCAR1)
PMUA: 114601800(BCAR1)
PRAF: 128419019(BCAR1)
ZVI: 118086452(BCAR1)
HCG: 128334566(BCAR1)
GJA: 107107898(BCAR1)
STOW: 125443644(BCAR1)
EMC: 129344103(BCAR1)
XLA: 108715363(bcar1.S) 398756(bcar1.L)
XTR: 447979(bcar1)
NPR: 108796559(BCAR1)
RTEM: 120917637(BCAR1)
BBUF: 120980274(BCAR1)
BGAR: 122920389(BCAR1)
MUO: 115470478(BCAR1)
GSH: 117359328(BCAR1)
DRE: 568309(bcar1)
SRX: 107726155(bcar1)
SANH: 107694928 107701029
SGH: 107583722 107596915
CCAR: 109108842 109109428
CAUA: 113061593 113118411
CGIB: 127934435 127977038
PTET: 122362867(bcar1)
LROH: 127180490(bcar1)
OMC: 131524147(bcar1)
PPRM: 120487727(bcar1)
RKG: 130088453(bcar1)
MAMB: 125254581(bcar1)
CIDE: 127499634
CERY: 137023396(bcar1)
MASI: 127417139 127455954
TROS: 130562897(bcar1)
TDW: 130435456(bcar1)
MANU: 129418917(bcar1)
IPU: 108264615
IFU: 128606779(bcar1)
PHYP: 113534477(bcar1)
SMEO: 124395692(bcar1)
TFD: 113652577(bcar1)
TVC: 132851182(bcar1)
TRN: 134322767(bcar1)
AMEX: 103028804(bcar1)
CMAO: 118801340(bcar1)
EEE: 113573599(bcar1)
CHAR: 105904514(bcar1)
TFS: 130536031(bcar1)
TNG: GSTEN00005088G001
LCO: 104939488(bcar1)
NCC: 104967430
TBEN: 117491646(bcar1)
CGOB: 115009962
PGEO: 117448018(bcar1)
GACU: 117532770(bcar1)
EMAC: 134882406(bcar1)
ELY: 117262291(bcar1)
EFO: 125887527(bcar1)
PLEP: 121939291
SLUC: 116040233(bcar1)
ECRA: 117948743(bcar1)
ESP: 116694598(bcar1)
PFLV: 114560766(bcar1)
PPUG: 119195779(bcar1)
AFB: 129108682(bcar1)
CLUM: 117732825(bcar1)
PSWI: 130194904(bcar1)
MSAM: 119894442(bcar1)
SCHU: 122874521(bcar1)
CUD: 121514840(bcar1)
ALAT: 119024324(bcar1)
MZE: 101473839(bcar1)
ONL: 100705076(bcar1)
OAU: 116330994(bcar1)
OLA: 101167688(bcar1)
OML: 112151935(bcar1)
CSAI: 133444082(bcar1)
XMA: 102230743(bcar1)
XCO: 114157230(bcar1)
XHE: 116708852(bcar1)
PRET: 103465773(bcar1)
PFOR: 103132472(bcar1)
PLAI: 106943028(bcar1)
PMEI: 106912250(bcar1)
GAF: 122835222(bcar1)
PPRL: 129361215(bcar1)
CVG: 107096741(bcar1)
CTUL: 119789784(bcar1)
GMU: 124877544(bcar1)
NFU: 107389510(bcar1)
KMR: 108246391(bcar1)
ALIM: 106510812
NWH: 119415890(bcar1)
AOCE: 111566681(bcar1)
MCEP: 125014911(bcar1)
CSEM: 103379847(bcar1)
POV: 109642993
SSEN: 122764718(bcar1)
HHIP: 117762747(bcar1)
HSP: 118110097(bcar1)
PPLT: 128444320(bcar1)
SMAU: 118314880(bcar1)
LCF: 108884593
SDU: 111234832(bcar1)
SLAL: 111647742(bcar1)
XGL: 120793057(bcar1)
HCQ: 109520705
SSCV: 125970399
SBIA: 133502724(bcar1)
PEE: 133402900(bcar1)
PTAO: 133477987(bcar1)
BPEC: 110169470(bcar1)
MALB: 109967267(bcar1)
BSPL: 114857897(bcar1)
SJO: 128359219(bcar1)
SASA: 106560839 106573733
STRU: 115151950 115196808
OTW: 112218531 112252351(bcar1)
OMY: 110494902 110520323
OGO: 124000508 124037227
ONE: 115109374 115134292
OKI: 109867161 109889323
OKE: 118396663 118400852
SALP: 111952497 111962362
SNH: 120053907 120066244
CCLU: 121531861(bcar1) 121576652
ELS: 105018442(bcar1)
SFM: 108918978(bcar1) 108933991
PKI: 111851927(bcar1) 111859378
AANG: 118227845(bcar1)
LOC: 102692374(bcar1)
PSPA: 121296232(bcar1) 121325511
ARUT: 117424712 117425067
PSEX: 120535285(bcar1)
LCM: 102355909 102362517(BCAR1)
CMK: 103176114
RTP: 109925586(bcar1)
CPLA: 122558450(bcar1)
HOC: 132823971(bcar1)
LERI: 129705071(bcar1)
PMRN: 116945818(BCAR1)
LRJ: 133340247(BCAR1)
BFO: 118417185
BBEL: 109473772
SPU: 576962
LPIC: 129253906
APLC: 110980128
ARUN: 117288973
SKO: 100374152
DPX: DAPPUDRAFT_301122
DMK: 116928786
PPOI: 119105803
DSV: 119466310
RSAN: 119376769
VDE: 111243927
VJA: 111267565
CSCU: 111614331 111617894 111617907
CVS: 136981350
UDV: 129232544
SDM: 118185702
LPOL: 106459976 106465694 106467109
PVUL: 126814536
BGT: 106079532
GAE: 121388774
HRF: 124148425
HRJ: 124292085
CRG: 105329588
CANU: 128190465
OED: 125663836
MYI: 110467508
PMAX: 117337074
MMER: 123548347
RPHI: 132759983
DPOL: 127846556
MAEA: 128243211
OBI: 106870453
OSN: 115221326
LJP: 135474787
LAK: 106169533 112042718
LLON: 135495483
NVE: 116604372
EPA: 110251985
ATEN: 116295152
DGT: 114532660
XEN: 124435797
HMG: 100206888
RES: 135691095
 » show all
Reference
PMID:17038317
  Authors
Modzelewska K, Newman LP, Desai R, Keely PJ
  Title
Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas.
  Journal
J Biol Chem 281:37527-35 (2006)
DOI:10.1074/jbc.M604342200
  Sequence
[hsa:9564]
Reference
PMID:10639512
  Authors
Brinkman A, van der Flier S, Kok EM, Dorssers LC
  Title
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
  Journal
J Natl Cancer Inst 92:112-20 (2000)
DOI:10.1093/jnci/92.2.112
  Sequence
[hsa:9564]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (22)   
   KEGG PATHWAY (22)   
Gene (715)   
   KEGG GENES (451)   
   KEGG MGENES (131)   
   RefGene (132)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (740)   

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