KEGG ORTHOLOGY: K05743

ORTHOLOGY: K05743

Entry

K05743                      KO

Symbol

LIMK1

Name

LIM domain kinase 1 [EC:2.7.11.1]

Pathway

map04360

Axon guidance

map04666

Fc gamma R-mediated phagocytosis

map04810

Regulation of actin cytoskeleton

map05135

Yersinia infection

map05170

Human immunodeficiency virus 1 infection

Disease

H01439

Williams-Beuren syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05743  LIMK1; LIM domain kinase 1
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05743  LIMK1; LIM domain kinase 1
  09158 Development and regeneration
   04360 Axon guidance
    K05743  LIMK1; LIM domain kinase 1
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05743  LIMK1; LIM domain kinase 1
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05743  LIMK1; LIM domain kinase 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05743  LIMK1; LIM domain kinase 1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05743  LIMK1; LIM domain kinase 1
Protein kinases [BR:ko01001]
Serine/threonine kinases: TKL group
  LISK family [OT]
   K05743  LIMK1; LIM domain kinase 1

Genes

HSA:	3984(LIMK1)

PTR:	463466(LIMK1)

PPS:	100973055(LIMK1)

GGO:	101152288(LIMK1)

PON:	100432626(LIMK1)

NLE:	100596304(LIMK1)

MCC:	699494(LIMK1)

MCF:	102131659(LIMK1)

CSAB:

103246620(LIMK1)

CATY:

105593347(LIMK1)

PANU:

101015319(LIMK1)

TGE:	112621403(LIMK1)

RRO:	104681244(LIMK1)

RBB:	108526525(LIMK1)

TFN:	117072560(LIMK1)

PTEH:

111547044(LIMK1)

CJC:	100395466(LIMK1)

SBQ:	101027894(LIMK1)

CSYR:

103276202(LIMK1)

MMUR:

105858833(LIMK1)

OGA:	100945796(LIMK1)

MMU:	16885(Limk1)

MCAL:

110294671(Limk1)

MPAH:

110339043(Limk1)

RNO:	65172(Limk1)

MCOC:

116068512(Limk1)

MUN:	110554207(Limk1)

CGE:	100770918(Limk1)

PLEU:

114693645(Limk1)

NGI:	103748493(Limk1)

HGL:	101698555(Limk1)

CPOC:

100712921(Limk1)

CCAN:

109686904(Limk1)

DORD:

105998505(Limk1)

DSP:	122114821(Limk1)

NCAR:

124970750

OCU:	100344018(LIMK1)

OPI:	101523041(LIMK1)

TUP:	102482698(LIMK1)

CFA:	489800(LIMK1)

VVP:	112935689(LIMK1)

VLG:	121488358(LIMK1)

AML:	100474547(LIMK1)

UMR:	103670230(LIMK1)

UAH:	113267782(LIMK1)

UAR:	123784733(LIMK1)

ELK:

111146226

LLV:

125091056

MPUF:

101682916(LIMK1)

ORO:	101373434(LIMK1)

EJU:	114214425(LIMK1)

ZCA:	113933133(LIMK1)

MLX:	117999499(LIMK1)

FCA:	101097861(LIMK1)

PYU:	121017453(LIMK1)

PBG:	122472026(LIMK1)

PTG:	102966775(LIMK1)

PPAD:

109250510(LIMK1)

AJU:	106977499(LIMK1)

HHV:	120247359(LIMK1)

BTA:	535225(LIMK1)

BOM:	102274463(LIMK1)

BBUB:

102391421(LIMK1)

CHX:	102177680(LIMK1)

OAS:	101110900(LIMK1)

ODA:	120878292(LIMK1)

CCAD:

122432852(LIMK1)

SSC:	100627618(LIMK1)

CFR:	102514976(LIMK1)

CBAI:

105082735(LIMK1)

CDK:	105089680(LIMK1)

VPC:	102541353(LIMK1)

BACU:

103014408(LIMK1)

LVE:	103076611(LIMK1)

OOR:	101279549(LIMK1)

DLE:	111182050(LIMK1)

PCAD:

102986111(LIMK1)

PSIU:

116740734(LIMK1)

ECB:	100062100(LIMK1)

EPZ:	103562888(LIMK1)

EAI:	106837110(LIMK1)

MYB:	102246788(LIMK1)

MYD:	102773291(LIMK1)

MMYO:

118656671(LIMK1)

MLF:	102431984(LIMK1)

MNA:	107526542(LIMK1)

PKL:	118702989(LIMK1)

HAI:	109385063(LIMK1)

DRO:	112314990(LIMK1)

SHON:

118992786(LIMK1)

AJM:	119056355(LIMK1)

PDIC:

114497639(LIMK1)

PHAS:

123806482(LIMK1)

MMF:	118641580(LIMK1)

RFQ:	117025162(LIMK1)

PALE:

102890594(LIMK1)

PGIG:

120591538(LIMK1)

PVP:	105299770(LIMK1)

RAY:	107502841(LIMK1)

MJV:	108398346(LIMK1)

TOD:	119241510(LIMK1)

SARA:

101547021(LIMK1)

LAV:	100675310(LIMK1)

TMU:

101340836

DNM:	101436025(LIMK1)

MDO:	100029925(LIMK1)

GAS:	123247504(LIMK1)

SHR:	100927614(LIMK1)

PCW:	110221244(LIMK1)

OAA:	100079954(LIMK1)

GGA:	373922(LIMK1)

PCOC:

116228209(LIMK1)

MGP:	100550102(LIMK1)

CJO:	107322610(LIMK1)

NMEL:

110407592(LIMK1)

ACYG:

106041038(LIMK1)

AFUL:

116497220(LIMK1)

TGU:	116809161(LIMK1)

LSR:	110475910(LIMK1)

SCAN:

103820230(LIMK1)

PMOA:

120513476(LIMK1)

OTC:	121346898(LIMK1)

PRUF:

121362980(LIMK1)

GFR:	102036824(LIMK1)

FAB:	101821749(LIMK1)

PHI:	102104770(LIMK1)

PMAJ:

107213029(LIMK1)

CCAE:

111942480

CCW:	120411027(LIMK1)

ETL:	114063800(LIMK1)

ZAB:	102066156 106629786

FPG:	101913490(LIMK1)

FCH:	102050858(LIMK1)

CLV:	102083884(LIMK1)

EGZ:	104131767(LIMK1)

NNI:	104012452(LIMK1)

TALA:

116964562(LIMK1)

ACHC:

115346840(LIMK1)

AAM:	106482280(LIMK1)

AROW:

112965051(LIMK1)

NPD:	112956670(LIMK1)

DNE:	112987391(LIMK1)

ASN:	102377214(LIMK1)

AMJ:	109282891(LIMK1)

GGN:	109289423(LIMK1)

PSS:

102456673

CMY:	102939678(LIMK1)

CPIC:

101953345(LIMK1)

CABI:

116818745(LIMK1)

MRV:	120387452(LIMK1)

ACS:	100561532(limk1)

PVT:	110083287(LIMK1)

SUND:

121917126(LIMK1)

PBI:	103060171(LIMK1)

PMUR:

107284701(LIMK1)

TSR:	106551456(LIMK1)

PGUT:

117667571(LIMK1)

VKO:	123036747(LIMK1)

PMUA:

114585555(LIMK1)

ZVI:	118097040(LIMK1)

GJA:	107112406(LIMK1)

XLA:	108709319(limk1.S) 397696(limk1.L)

XTR:	780362(limk1)

NPR:	108790883(LIMK1)

RTEM:

120927551(LIMK1)

BBUF:

120994799(LIMK1)

BGAR:

122930486(LIMK1)

DRE:	101883214(limk1b) 735292(limk1a)

SRX:	107713159 107720456 107750118

SANH:

107663742 107675197 107688062 107697333

SGH:	107551278 107570612 107582020 107587268

CCAR:

109045380 109102825(limk1)

CAUA:

113038143 113058249 113070082 113115454

IPU:	108278922(limk1b) 108280842(limk1a)

PHYP:

113541373 113542991(limk1)

SMEO:

124397601(limk1b) 124403261(limk1a)

TFD:	113652858(limk1a) 113662485(limk1b)

AMEX:

103039384 103047204(limk1)

EEE:	113573979(limk1) 113582524

TRU:	101061422 101061585 115251474

TNG:	GSTEN00004976G001 GSTEN00007894G001 GSTEN00007895G001 GSTEN00010660G001

LCO:	104925782 104936804

NCC:	104958830(limk1) 104967133

CGOB:

115017891 115019338

ELY:	117259710(limk1a) 117261872

PLEP:

121943095(limk1a) 121952929

SLUC:

116037072 116047999(limk1a)

ECRA:

117939199(limk1a) 117956106

PFLV:

114553349 114566405

GAT:	120818989(limk1a) 120821753

PPUG:

119214938(limk1a) 119215099

MSAM:

119882907(limk1a) 119894840

CUD:	121518639 121522321(limk1a)

MZE:	101471960 101472506

ONL:	100693040 100704692

OAU:	116314790(limk1a) 116317304

OLA:	101162943 101168972

OML:	112142928 112149831(limk1a)

XMA:	102219535 102225878

XCO:	114133387 114152849

XHE:	116708144(limk1) 116728867

PRET:

103474554 103475633(limk1)

PFOR:

103139280(limk1) 103155194

PLAI:

106950040(limk1) 106957248

PMEI:

106910411(limk1) 106927273

GAF:	122833067(limk1a) 122844795

CVG:	107098346(limk1) 107103990

CTUL:

119782836(limk1a) 119794016

GMU:	124875968 124884561(limk1a)

NFU:	107380372 107386885(limk1)

KMR:	108238894 108246059(limk1a)

ALIM:

106515472 106523471(limk1)

NWH:	119410605(limk1a) 119420511

AOCE:

111573003(limk1) 111587400

CSEM:

103378129 103395024(limk1)

POV:	109630090 109635680

SSEN:

122773471(limk1a) 122779799

HHIP:

117773238(limk1a) 117774399

LCF:	108886370 108893306

SDU:	111217057 111228045

SLAL:

111647479 111650934

XGL:	120792004(limk1a) 120802446

HCQ:	109525493 109532077

BPEC:

110154070 110158542

MALB:

109960240(limk1) 109970502

SASA:

106581050 106612833

OTW:	112237570 112267047

OMY:	110503880 110507118

OGO:	123992784 124005815

ONE:	115136798 115141783

SALP:

111959168(limk1) 111982683

SNH:	120018563 120028822

ELS:	105006773 105031063(limk1)

SFM:	108921218 108922441

PKI:	111847119 111852924

AANG:

118210176 118235999

LOC:	102697125(limk1)

PSPA:

121308656(limk1a)

ARUT:

117429831 117430751

LCM:	102357921(LIMK1)

CMK:	103180508(limk1a)

RTP:

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG1848(LIMK1)

DER:

6551151

DSE:

6618572

DSI:	Dsimw501_GD15924(Dsim_GD15924)

DYA:	Dyak_GE16209

DSR:

110178202

DPO:	Dpse_GA14953

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI16163

DAZ:

DNV:

DHE:

DVI:

MDE:

SCAC:

LCQ:

AGA:	AgaP_AGAP011710

ACOZ:

AARA:

AAG:

AALB:

CQU:	CpipJ_CPIJ000717

CPII:

120416634

CNS:	116338456 116352592

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:	111421650 111422566

BMOR:

101745432

BMAN:

114242952

MSEX:

115455649

DPL:	KGM_206833

BANY:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

HAW:

TNL:

OFU:	114360149 114362760

PXY:	105384434 105391573

BTAB:

109036960

DCI:	103515477 103519945

CLEC:

106672580

NLU:

111043244

PHU:	Phum_PHUM255000

FOC:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_314766

DMK:

116928735

PVM:	113823440 113823448

PJA:

PCHN:

HAME:

PCLA:

HAZT:

DSV:

RSAN:

RMP:

DPTE:

DFR:

CSCU:

PTEP:

SDM:	118183892 118188908

HRO:	HELRODRAFT_83299

LGI:	LOTGIDRAFT_103637

PCAN:

GAE:

MYI:

PMAX:

OBI:

OSN:

LAK:

SMM:	Smp_047870.1

OVI:	T265_01312

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114538254 114543434

XEN:

124434632

AQU:

100634910

TVS:	TRAVEDRAFT_170594

DSQ:	DICSQDRAFT_137713

PCO:	PHACADRAFT_101271

SHS:	STEHIDRAFT_105665

PSQ:	PUNSTDRAFT_106884

ADL:	AURDEDRAFT_110018

FME:	FOMMEDRAFT_166557

GTR:	GLOTRDRAFT_60563

LBC:	LACBIDRAFT_248887

MPR:	MPER_07246

MRR:

Moror_783

CCI:	CC1G_09729

ABV:	AGABI2DRAFT210461(AGABI2DRAFT_210461)

CPUT:

CONPUDRAFT_110356

SLA:	SERLADRAFT_413415

PFP:	PFL1_04363

PGR:	PGTG_11481

MBR:	MONBRDRAFT_1780 MONBRDRAFT_21811(Mbre_LIMK1)

SRE:	PTSG_03858 PTSG_07236 PTSG_08837

DDI:	DDB_G0283391(kinX) DDB_G0289859(kxcA)

DPP:	DICPUDRAFT_157827

DFA:	DFA_08930(kinX) DFA_09369(kxcA)

» show all

Reference

PMID:10436159

Authors

Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S

Title

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Journal

Science 285:895-8 (1999)
DOI:10.1126/science.285.5429.895

Reference

PMID:8183554

Authors

Mizuno K, Okano I, Ohashi K, Nunoue K, Kuma K, Miyata T, Nakamura T

Title

Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif.

Journal

Oncogene 9:1605-12 (1994)

Sequence

[hsa:3984]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1300)   
   KEGG GENES (498)   
   KEGG MGENES (237)   
   RefGene (558)   
   OC (7)   
Literature (2)   
   PubMed (2)   
All databases (1317)   

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