KEGG ORTHOLOGY: K05743

ORTHOLOGY: K05743

Entry

K05743                      KO

Symbol

LIMK1

Name

LIM domain kinase 1 [EC:2.7.11.1]

Pathway

map04360

Axon guidance

map04666

Fc gamma R-mediated phagocytosis

map04810

Regulation of actin cytoskeleton

map05135

Yersinia infection

map05170

Human immunodeficiency virus 1 infection

Disease

H01439

Williams-Beuren syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05743  LIMK1; LIM domain kinase 1
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05743  LIMK1; LIM domain kinase 1
  09158 Development and regeneration
   04360 Axon guidance
    K05743  LIMK1; LIM domain kinase 1
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05743  LIMK1; LIM domain kinase 1
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05743  LIMK1; LIM domain kinase 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05743  LIMK1; LIM domain kinase 1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05743  LIMK1; LIM domain kinase 1
Protein kinases [BR:ko01001]
Serine/threonine kinases: TKL group
  LISK family [OT]
   K05743  LIMK1; LIM domain kinase 1

Genes

HSA:	3984(LIMK1)

PTR:	463466(LIMK1)

PPS:	100973055(LIMK1)

GGO:	101152288(LIMK1)

PON:	100432626(LIMK1)

PPYG:

129040848(LIMK1)

NLE:	100596304(LIMK1)

HMH:	116811623(LIMK1)

SSYN:

129489766(LIMK1)

MCC:	699494(LIMK1)

MCF:	102131659(LIMK1)

MTHB:

126950355

MNI:	105466367(LIMK1)

CSAB:

103246620(LIMK1)

CATY:

105593347(LIMK1)

PANU:

101015319(LIMK1)

TGE:	112621403(LIMK1)

MLEU:

105550336(LIMK1)

RRO:	104681244(LIMK1)

RBB:	108526525(LIMK1)

TFN:	117072560(LIMK1)

PTEH:

111547044(LIMK1)

CANG:

105503656(LIMK1)

CJC:	100395466(LIMK1)

SBQ:	101027894(LIMK1)

CIMI:

108307856(LIMK1)

ANAN:

105714916(LIMK1)

CSYR:

103276202(LIMK1)

MMUR:

105858833(LIMK1)

LCAT:

123632606(LIMK1)

PCOQ:

105807094(LIMK1)

OGA:	100945796(LIMK1)

MMU:	16885(Limk1)

MCAL:

110294671(Limk1)

MPAH:

110339043(Limk1)

RNO:	65172(Limk1)

MCOC:

116068512(Limk1)

ANU:	117698263(Limk1)

MUN:	110554207(Limk1)

CGE:	100770918(Limk1)

MAUA:

101844415(Limk1)

PROB:

127236893(Limk1)

PLEU:

114693645(Limk1)

MORG:

121446420(Limk1)

MFOT:

126516009

AAMP:

119824844(Limk1)

NGI:	103748493(Limk1)

HGL:	101698555(Limk1)

CPOC:

100712921(Limk1)

CCAN:

109686904(Limk1)

DORD:

105998505(Limk1)

DSP:	122114821(Limk1)

PLOP:

125368403(Limk1)

NCAR:

124970750

MMMA:

107147031(Limk1)

OCU:

100344018

OPI:	101523041(LIMK1)

TUP:	102482698(LIMK1)

GVR:	103597746(LIMK1)

CFA:	489800(LIMK1)

CLUD:

112646136(LIMK1)

VVP:	112935689(LIMK1)

VLG:	121488358(LIMK1)

NPO:	129520154(LIMK1)

AML:	100474547(LIMK1)

UMR:	103670230(LIMK1)

UAH:	113267782(LIMK1)

UAR:	123784733(LIMK1)

ELK:

111146226

LLV:

125091056

MPUF:

101682916(LIMK1)

MNP:	132026631(LIMK1)

MLK:	131819692(LIMK1)

NVS:	122896063(LIMK1)

ORO:	101373434(LIMK1)

EJU:	114214425(LIMK1)

ZCA:	113933133(LIMK1)

MLX:	117999499(LIMK1)

NSU:	110589798(LIMK1)

LWW:	102736002(LIMK1)

FCA:	101097861(LIMK1)

PYU:	121017453(LIMK1)

PBG:	122472026(LIMK1)

PVIV:

125154596(LIMK1)

LRUF:

124519234

PTG:	102966775(LIMK1)

PPAD:

109250510(LIMK1)

PUC:

125928179

AJU:

106977499

HHV:	120247359(LIMK1)

BTA:	535225(LIMK1)

BOM:	102274463(LIMK1)

BBUB:

102391421(LIMK1)

BBIS:

104998898(LIMK1)

CHX:	102177680(LIMK1)

OAS:	101110900(LIMK1)

BTAX:

128066654(LIMK1)

ODA:	120878292(LIMK1)

CCAD:

122432852(LIMK1)

MBEZ:

129545614(LIMK1)

SSC:	100627618(LIMK1)

CFR:	102514976(LIMK1)

CBAI:

105082735(LIMK1)

CDK:	105089680(LIMK1)

VPC:	102541353(LIMK1)

BACU:

103014408(LIMK1)

BMUS:

118881988(LIMK1)

LVE:	103076611(LIMK1)

OOR:	101279549(LIMK1)

DLE:	111182050(LIMK1)

PCAD:

102986111(LIMK1)

PSIU:

116740734(LIMK1)

NASI:

112401140(LIMK1)

ECB:	100062100(LIMK1)

EPZ:	103562888(LIMK1)

EAI:	106837110(LIMK1)

MYB:	102246788(LIMK1)

MYD:	102773291(LIMK1)

MMYO:

118656671(LIMK1)

MLF:	102431984(LIMK1)

MDT:	132233181(LIMK1)

PKL:	118702989(LIMK1)

EFUS:

103286048(LIMK1)

MNA:	107526542(LIMK1)

DRO:	112314990(LIMK1)

SHON:

118992786(LIMK1)

AJM:	119056355(LIMK1)

PDIC:

114497639(LIMK1)

PHAS:

123806482(LIMK1)

MMF:	118641580(LIMK1)

PPAM:

129083413(LIMK1)

HAI:	109385063(LIMK1)

RFQ:	117025162(LIMK1)

PALE:

102890594(LIMK1)

PGIG:

120591538(LIMK1)

PVP:	105299770(LIMK1)

RAY:	107502841(LIMK1)

MJV:	108398346(LIMK1)

TOD:	119241510(LIMK1)

SARA:

101547021(LIMK1)

SETR:

126031287(LIMK1)

LAV:	100675310(LIMK1)

TMU:

101340836

ETF:	101652935(LIMK1)

DNM:	101436025(LIMK1)

MDO:	100029925(LIMK1)

GAS:	123247504(LIMK1)

SHR:	100927614(LIMK1)

AFZ:

127558702

PCW:	110221244(LIMK1)

TVP:	118858355(LIMK1)

OAA:	100079954(LIMK1)

GGA:	373922(LIMK1)

PCOC:

116228209(LIMK1)

MGP:	100550102(LIMK1)

CJO:	107322610(LIMK1)

TPAI:

128083599(LIMK1)

LMUT:

125703073(LIMK1)

NMEL:

110407592(LIMK1)

APLA:

119713270(LIMK1)

ACYG:

106041038(LIMK1)

CATA:

118254105(LIMK1)

AFUL:

116497220(LIMK1)

TGU:	116809161(LIMK1)

LSR:	110475910(LIMK1)

SCAN:

103820230(LIMK1)

PMOA:

120513476(LIMK1)

OTC:	121346898(LIMK1)

PRUF:

121362980(LIMK1)

GFR:	102036824(LIMK1)

FAB:	101821749(LIMK1)

OMA:	130260814(LIMK1)

PHI:	102104770(LIMK1)

PMAJ:

107213029(LIMK1)

CCAE:

111942480

CCW:	120411027(LIMK1)

ETL:	114063800(LIMK1)

ZAB:	102066156 106629786

ZLE:	135455810(LIMK1)

ACHL:

103804724(LIMK1)

SVG:	106856236(LIMK1)

MMEA:

130586627(LIMK1)

HRT:	120761305(LIMK1)

SATI:

136369962(LIMK1)

FPG:	101913490(LIMK1)

FCH:	102050858(LIMK1)

NNT:	104401886(LIMK1)

SHAB:

115603121(LIMK1)

TALA:

116964562(LIMK1)

ACHC:

115346840(LIMK1)

HLE:	104843148(LIMK1)

AGEN:

126039944

GCL:

127024308

DPUB:

104300247(LIMK1)

EGZ:	104131767(LIMK1)

NNI:	104012452(LIMK1)

PCRI:

104038126(LIMK1)

AFOR:

103896575(LIMK1)

CLV:	102083884(LIMK1)

CUCA:

128854191(LIMK1)

TEO:	104377574(LIMK1)

CVF:	104289856(LIMK1)

RTD:	128913138(LIMK1)

AAM:	106482280(LIMK1)

AROW:

112965051(LIMK1)

NPD:	112956670(LIMK1)

TGT:	104575273(LIMK1)

DNE:	112987391(LIMK1)

SCAM:

104146217(LIMK1)

ASN:	102377214(LIMK1)

AMJ:	109282891(LIMK1)

GGN:	109289423(LIMK1)

PSS:

102456673

CMY:	102939678(LIMK1)

CCAY:

125623880(LIMK1)

DCC:	119844839(LIMK1)

CPIC:

101953345(LIMK1)

CABI:

116818745(LIMK1)

MRV:	120387452(LIMK1)

ACS:	100561532(limk1)

ASAO:

132763318(LIMK1)

PVT:	110083287(LIMK1)

SUND:

121917126(LIMK1)

PBI:	103060171(LIMK1)

PMUR:

107284701(LIMK1)

CTIG:

120309224(LIMK1)

TSR:	106551456(LIMK1)

PGUT:

117667571(LIMK1)

APRI:

131188903(LIMK1)

PTEX:

113441435(LIMK1)

NSS:	113414667(LIMK1)

VKO:	123036747(LIMK1)

PMUA:

114585555(LIMK1)

PRAF:

128402646(LIMK1)

ZVI:	118097040(LIMK1)

HCG:	128336039(LIMK1)

GJA:	107112406(LIMK1)

STOW:

125446073(LIMK1)

EMC:	129345024(LIMK1)

XLA:	108709319(limk1.S) 397696(limk1.L)

XTR:	780362(limk1)

NPR:	108790883(LIMK1)

RTEM:

120927551(LIMK1)

BBUF:

120994799(LIMK1)

BGAR:

122930486(LIMK1)

MUO:	115456830(LIMK1)

GSH:	117348984(LIMK1)

DRE:	101883214(limk1b) 735292(limk1a)

SRX:	107713159 107720456 107750118

SANH:

107663742 107675197 107688062 107697333

SGH:	107551278 107570612 107582020 107587268

CCAR:

109045380 109102825(limk1)

CAUA:

113038143 113058249 113070082 113115454

CGIB:

127941993 127972822 127986136

PTET:

122326436(limk1b) 122359015(limk1a)

LROH:

127152882(limk1b) 127157580(limk1a)

OMC:	131528714(limk1b) 131554305(limk1a)

PPRM:

120464560(limk1a) 120482638(limk1b)

RKG:	130095455(limk1b) 130104234(limk1a)

MAMB:

125248102(limk1a) 125252900(limk1b)

CIDE:

127496260 127503339

CERY:

137005461(limk1a) 137012673(limk1b)

MASI:

127422262 127428983 127429797

TROS:

130564357(limk1a) 130569791(limk1b)

TDW:	130408059(limk1b) 130429118(limk1a)

MANU:

129424353(limk1b) 129437592(limk1a)

IPU:	108278922(limk1b) 108280842(limk1a)

IFU:	128621921(limk1b) 128623992(limk1a)

PHYP:

113541373 113542991(limk1)

SMEO:

124397601(limk1b) 124403261(limk1a)

TFD:	113652858(limk1a) 113662485(limk1b)

TVC:	132849486(limk1a) 132860003(limk1b)

TRN:	134302195(limk1a) 134330303(limk1b)

AMEX:

103039384(limk1b) 103047204(limk1a)

CMAO:

118797270(limk1a) 118820219(limk1b)

EEE:	113573979(limk1) 113582524

CHAR:

105901391(limk1a) 105902408

TRU:	101061422 101061585 115251474

TFS:	130535053 130535054 130537612

TNG:	GSTEN00004976G001 GSTEN00007894G001 GSTEN00007895G001 GSTEN00010660G001

LCO:	104925782 104936804

NCC:	104958830(limk1) 104967133

TBEN:

117470382(limk1a) 117490251

CGOB:

115017891 115019338

PGEO:

117457269(limk1a) 117458275

GACU:

117540072 117552189(limk1a)

EMAC:

134872580 134880306(limk1a)

ELY:	117259710(limk1a) 117261872

EFO:	125888849(limk1a) 125898732

PLEP:

121943095(limk1a) 121952929

SLUC:

116037072 116047999(limk1a)

ECRA:

117939199(limk1a) 117956106

ESP:	116673323(limk1) 116701095

PFLV:

114553349 114566405

GAT:	120818989(limk1a) 120821753

PPUG:

119214938(limk1a) 119215099

AFB:	129110520(limk1a) 129113327

CLUM:

117741629(limk1a) 117742567

PSWI:

130191851 130210533(limk1a)

MSAM:

119882907(limk1a) 119894840

SCHU:

122878812(limk1a) 122888876

CUD:	121518639 121522321(limk1a)

ALAT:

119005839(limk1a) 119031328

MZE:	101471960 101472506

ONL:	100693040 100704692

OAU:	116314790(limk1a) 116317304

OLA:	101162943 101168972

OML:	112142928 112149831(limk1a)

CSAI:

133441730(limk1a) 133459605

XMA:	102219535 102225878

XCO:	114133387 114152849

XHE:	116708144(limk1) 116728867

PRET:

103474554 103475633(limk1)

PFOR:

103139280(limk1) 103155194

PLAI:

106950040(limk1) 106957248

PMEI:

106910411(limk1) 106927273

GAF:	122833067(limk1a) 122844795

PPRL:

129358789(limk1a) 129373492

CVG:	107098346(limk1) 107103990

CTUL:

119782836(limk1a) 119794016

GMU:	124875968 124884561(limk1a)

NFU:	107380372 107386885(limk1)

KMR:	108238894 108246059(limk1a)

ALIM:

106515472 106523471(limk1)

NWH:	119410605(limk1a) 119420511

AOCE:

111573003(limk1) 111587400

MCEP:

125013516(limk1a) 125021400

CSEM:

103378129 103395024(limk1)

POV:	109630090 109635680

SSEN:

122773471(limk1a) 122779799

HHIP:

117773238(limk1a) 117774399

HSP:	118106409(limk1a) 118122048

PPLT:

128439991(limk1a) 128457650

SMAU:

118299363(limk1a) 118300558

LCF:	108886370 108893306

SDU:	111217057 111228045

SLAL:

111647479 111650934

XGL:	120792004(limk1a) 120802446

HCQ:	109525493 109532077

SSCV:

125972096 125982300

SBIA:

133491424 133504709(limk1a)

PEE:	133404831(limk1a) 133415802

PTAO:

133466821 133481922(limk1a)

BPEC:

110154070 110158542

MALB:

109960240(limk1) 109970502

BSPL:

114868349(limk1a) 114869663

SJO:	128360350(limk1a) 128371103

SASA:

106581050 106612833

STRU:

115163364 115206291

OTW:	112237570 112267047

OMY:	110503880 110507118

OGO:	123992784 124005815

ONE:	115136798 115141783

OKI:	109875615 109905667

OKE:	118370706 118372754

SALP:

111959168(limk1) 111982683

SNH:	120018563 120028822

CCLU:

121566204 121567914

ELS:	105006773 105031063(limk1)

SFM:	108921218 108922441

PKI:	111847119 111852924

AANG:

118210176 118235999

LOC:	102697125(limk1)

PSPA:

121308656(limk1a)

ARUT:

117429831 117430751

PSEX:

120531494(limk1a)

LCM:	102357921(LIMK1)

CMK:	103180508(limk1a)

RTP:	109912522(limk1a)

CPLA:

122564111(limk1a)

HOC:	132830305(limk1a)

LERI:

129710756(limk1a)

PMRN:

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG1848(LIMK1)

DER:

6551151

DSE:

6618572

DSI:	Dsimw501_GD15924(Dsim_GD15924)

DYA:	Dyak_GE16209

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI16163

DAZ:

DNV:

DHE:

DVI:

BDR:

RZE:

AOQ:

TDA:	119662359 119665158 119669342 119669345 119669346

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

ACOZ:

AARA:

ASTE:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ000717

CPII:

120416634

CNS:	116338456 116352592

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105670791(LIMK1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

AGIF:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:	111421650 111422566

BMOR:

101745432

BMAN:

114242952

MSEX:

115455649

DPL:	KGM_206833

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

AAGE:

HAW:	110373651(Limk1)

HZE:

124639687

TNL:

113494411

SLIU:

111360184

OFU:	114360149 114362760

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

BTAB:

DCI:	103515477 103519945

CLEC:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM255000

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_314766

DMK:

116928735

DPZ:

124310978

PVM:	113823440 113823448

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

ESN:

MNZ:

HAZT:

PPOI:

ISC:

DSV:

RSAN:

RMP:

DPTE:

DFR:

CSCU:

CVS:	136985021(LIMK1)

PTEP:

107438877 107454877

ABRU:

129975658 129984405

UDV:	129227393 129233408 129233658

SDM:	118183892 118188908

LPOL:

106468301

PMEO:

129597246

HRO:	HELRODRAFT_83299

LGI:	LOTGIDRAFT_103637

PCAN:

GAE:

CVN:

OED:

MYI:

PMAX:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_047870.1

OVI:	T265_01312

LLON:

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114538254 114543434

XEN:

124434632

RES:

135683152

AQU:

100634910

TVS:	TRAVEDRAFT_170594

DSQ:	DICSQDRAFT_137713

PCO:	PHACADRAFT_101271

SHS:	STEHIDRAFT_105665

PSQ:	PUNSTDRAFT_106884

ADL:	AURDEDRAFT_110018

FME:	FOMMEDRAFT_166557

GTR:	GLOTRDRAFT_60563

LBC:	LACBIDRAFT_248887

CCI:	CC1G_09729

ABV:	AGABI2DRAFT210461(AGABI2DRAFT_210461)

MPR:	MPER_07246

MRR:

Moror_783

E1B28_013508

CPUT:

CONPUDRAFT_110356

SLA:	SERLADRAFT_413415

PFP:	PFL1_04363

PGR:	PGTG_11481

MBR:	MONBRDRAFT_1780 MONBRDRAFT_21811(Mbre_LIMK1)

SRE:	PTSG_03858 PTSG_07236 PTSG_08837

DDI:	DDB_G0283391(kinX) DDB_G0289859(kxcA)

DPP:	DICPUDRAFT_157827

DFA:	DFA_08930(kinX) DFA_09369(kxcA)

» show all

Reference

PMID:10436159

Authors

Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S

Title

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Journal

Science 285:895-8 (1999)
DOI:10.1126/science.285.5429.895

Reference

PMID:8183554

Authors

Mizuno K, Okano I, Ohashi K, Nunoue K, Kuma K, Miyata T, Nakamura T

Title

Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif.

Journal

Oncogene 9:1605-12 (1994)

Sequence

[hsa:3984]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1711)   
   KEGG GENES (752)   
   KEGG MGENES (394)   
   RefGene (558)   
   OC (7)   
Literature (2)   
   PubMed (2)   
All databases (1728)   

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ORTHOLOGY: K05744

Entry

K05744                      KO

Symbol

LIMK2

Name

LIM domain kinase 2 [EC:2.7.11.1]

Pathway

map04360

Axon guidance

map04666

Fc gamma R-mediated phagocytosis

map04810

Regulation of actin cytoskeleton

map05170

Human immunodeficiency virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05744  LIMK2; LIM domain kinase 2
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05744  LIMK2; LIM domain kinase 2
  09158 Development and regeneration
   04360 Axon guidance
    K05744  LIMK2; LIM domain kinase 2
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05744  LIMK2; LIM domain kinase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05744  LIMK2; LIM domain kinase 2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05744  LIMK2; LIM domain kinase 2
Protein kinases [BR:ko01001]
Serine/threonine kinases: TKL group
  LISK family [OT]
   K05744  LIMK2; LIM domain kinase 2

Genes

HSA:	3985(LIMK2)

PTR:	458970(LIMK2)

PPS:	100978324(LIMK2)

GGO:	101133437(LIMK2)

PON:	100460494(LIMK2)

PPYG:

129023551(LIMK2)

NLE:	100586214(LIMK2)

HMH:	116458826(LIMK2)

SSYN:

129468612(LIMK2)

MCC:	716614(LIMK2)

MCF:	102136171(LIMK2)

MTHB:

126963929

MNI:	105487207(LIMK2)

CSAB:

103223186(LIMK2)

CATY:

105575749(LIMK2)

PANU:

101017879(LIMK2)

TGE:	112632978(LIMK2)

MLEU:

105538964(LIMK2)

RRO:	104660353(LIMK2)

RBB:	108527615(LIMK2)

TFN:	117096217(LIMK2)

PTEH:

111521834(LIMK2)

CANG:

105509193(LIMK2)

CJC:	100396965(LIMK2)

SBQ:	101031302(LIMK2)

CIMI:

108283288(LIMK2)

ANAN:

105730266(LIMK2)

CSYR:

103258527(LIMK2)

MMUR:

105870954(LIMK2)

LCAT:

123625862(LIMK2)

PCOQ:

105821289(LIMK2)

OGA:	100944489(LIMK2)

MMU:	16886(Limk2)

MCAL:

110304738(Limk2)

MPAH:

110330408(Limk2)

RNO:	29524(Limk2)

MCOC:

116069764(Limk2)

ANU:	117713026(Limk2)

MUN:	110557623(Limk2)

CGE:	100760910(Limk2)

MAUA:

101830855(Limk2)

PROB:

127233784(Limk2)

PLEU:

114694032(Limk2)

MORG:

121436566 121459809

MFOT:

126500782

AAMP:

119826815(Limk2)

NGI:	103740428(Limk2)

HGL:	101698063(Limk2)

CPOC:

100720658(Limk2)

CCAN:

109696918(Limk2)

DORD:

105984318(Limk2)

DSP:	122095919(Limk2)

PLOP:

125349299(Limk2)

NCAR:

124990701

MMMA:

107158475

OCU:

100356835

OPI:	101532959(LIMK2)

TUP:	102477125(LIMK2)

GVR:	103605064(LIMK2)

CFA:	486363(LIMK2)

CLUD:

112676829(LIMK2)

VVP:	112909819(LIMK2)

VLG:	121475393(LIMK2)

NPO:	129507902(LIMK2)

AML:	100478557(LIMK2)

UMR:	103681084(LIMK2)

UAH:	113245055(LIMK2)

UAR:	123788184(LIMK2)

ELK:

111160080

LLV:

125082483

MPUF:

101684485(LIMK2)

MNP:	132023348(LIMK2)

MLK:	131811804(LIMK2)

NVS:	122903242(LIMK2)

ORO:	101365602(LIMK2)

EJU:	114225180(LIMK2)

ZCA:	113912331(LIMK2)

MLX:	118018669(LIMK2)

NSU:	110592506(LIMK2)

LWW:	102738570(LIMK2)

FCA:	101096766(LIMK2)

PYU:	121022669(LIMK2)

PCOO:

112870101(LIMK2)

PBG:	122470961(LIMK2)

PVIV:

125148861(LIMK2)

LRUF:

124518218

PTG:	102952158(LIMK2)

PPAD:

109253609(LIMK2)

PUC:

125913971

AJU:

106983306

HHV:	120227439(LIMK2)

BTA:	513539(LIMK2)

BOM:	102282980(LIMK2)

BIU:	109571147(LIMK2)

BBUB:

102406228(LIMK2)

BBIS:

104980159(LIMK2)

CHX:	102171364(LIMK2)

OAS:	101114815(LIMK2)

BTAX:

128062055(LIMK2)

ODA:	120871257(LIMK2)

CCAD:

122420691(LIMK2)

MBEZ:

129542806(LIMK2)

SSC:	100156359(LIMK2)

CFR:	102512622(LIMK2)

CBAI:

105066098(LIMK2)

CDK:	105099426(LIMK2)

VPC:	102531440(LIMK2)

BACU:

103015530(LIMK2)

BMUS:

118906797

LVE:	103087898(LIMK2)

OOR:

101273335

DLE:

111162707

PCAD:

102990180(LIMK2)

PSIU:

116765143

NASI:

112415112

ECB:	100058419(LIMK2)

EPZ:	103565974(LIMK2)

EAI:	106826900(LIMK2)

MYB:	102240139(LIMK2)

MYD:	102753215(LIMK2)

MMYO:

118678110(LIMK2)

MLF:	102437257(LIMK2)

MDT:	132222065(LIMK2)

PKL:	118725653(LIMK2)

EFUS:

103286833(LIMK2)

MNA:	107526171(LIMK2)

DRO:	112310817(LIMK2)

SHON:

118991309(LIMK2)

AJM:	119064893(LIMK2)

PDIC:

114509199(LIMK2)

PHAS:

123810960(LIMK2)

MMF:	118640005(LIMK2)

PPAM:

129087429(LIMK2)

HAI:	109383094(LIMK2)

RFQ:	117017518(LIMK2)

PALE:

102896062(LIMK2)

PGIG:

120602015(LIMK2)

PVP:	105308348(LIMK2)

RAY:	107521058(LIMK2)

MJV:	108386414(LIMK2)

TOD:	119244857(LIMK2)

SARA:

101538827(LIMK2)

SETR:

126030738(LIMK2)

LAV:	100656340(LIMK2)

TMU:

101345292

ETF:	101646862(LIMK2)

DNM:	101418223(LIMK2)

MDO:	100028612(LIMK2)

GAS:	123245448(LIMK2)

SHR:	100929464(LIMK2)

AFZ:

127545704

PCW:	110215131(LIMK2)

TVP:	118833929(LIMK2)

OAA:	100074515(LIMK2)

GGA:	396010(LIMK2)

PCOC:

116228441(LIMK2)

MGP:	100548509(LIMK2)

CJO:	107321328(LIMK2)

TPAI:

128083911(LIMK2)

LMUT:

125701696(LIMK2)

NMEL:

110406552(LIMK2)

APLA:

101794154(LIMK2)

ACYG:

106031338(LIMK2)

CATA:

118252848(LIMK2)

AFUL:

116496228(LIMK2)

TGU:	100223808(LIMK2)

LSR:	110481380(LIMK2)

SCAN:

103818028(LIMK2)

PMOA:

120510251(LIMK2)

OTC:	121344518(LIMK2)

PRUF:

121364886(LIMK2)

GFR:	102032107(LIMK2)

FAB:	101818799(LIMK2)

OMA:	130259795(LIMK2)

PHI:	102113067(LIMK2)

PMAJ:

107211532(LIMK2)

CCAE:

111936608

CCW:	104688553(LIMK2)

CBRC:

103614182(LIMK2)

ETL:	114056632(LIMK2)

ZAB:	102063683(LIMK2)

ZLE:	135454434(LIMK2)

ACHL:

103809119(LIMK2)

SVG:	106864916(LIMK2)

MMEA:

130578017(LIMK2)

HRT:	120760370(LIMK2)

SATI:

136368843(LIMK2)

FPG:	101921786(LIMK2)

FCH:	102054991(LIMK2)

CCRI:

104157821(LIMK2)

NNT:	104408266(LIMK2)

SHAB:

115614103(LIMK2)

ACUN:

113486061(LIMK2)

TALA:

104366914(LIMK2)

ACHC:

115346159(LIMK2)

HALD:

104315834(LIMK2)

HLE:

104836302

AGEN:

126040482

GCL:

127022953

CSTI:

104558803(LIMK2)

LDI:	104346063(LIMK2)

MNB:	103769404(LIMK2)

DPUB:

104309627(LIMK2)

AVIT:

104276702

BRHI:

104497039(LIMK2)

EGZ:	104129846(LIMK2)

NNI:	104011454(LIMK2)

PCRI:

104032678(LIMK2)

PCAO:

104044069(LIMK2)

PADL:

103922685(LIMK2)

AFOR:

103899542(LIMK2)

FGA:

104080904

GSTE:

104264909(LIMK2)

CLV:	102088187(LIMK2)

MUI:

104538280

PGUU:

104466912

PLET:

104627172(LIMK2)

EHS:	104504070(LIMK2)

CMAC:

104480013(LIMK2)

CUCA:

104068429(LIMK2)

TEO:	104381469(LIMK2)

BREG:

104635433(LIMK2)

OHA:	104331418(LIMK2)

ACAR:

104524095(LIMK2)

CPEA:

104395142(LIMK2)

CVF:	104289616(LIMK2)

RTD:	128917067(LIMK2)

AAM:	106486256(LIMK2)

AROW:

112970575(LIMK2)

NPD:	112946011(LIMK2)

TGT:	104581131(LIMK2)

DNE:	112994626(LIMK2)

SCAM:

104152201(LIMK2)

ASN:	102373879(LIMK2)

AMJ:	102576616(LIMK2)

CPOO:

109312857(LIMK2)

GGN:	109290360(LIMK2)

PSS:	102445206(LIMK2)

CMY:	102932658(LIMK2)

CCAY:

125623142(LIMK2)

DCC:	119843478(LIMK2)

CPIC:

101931739(LIMK2)

TST:	117888082(LIMK2)

CABI:

116820930

MRV:	120386282(LIMK2)

ASAO:

132781186(LIMK2)

PVT:	110081951(LIMK2)

PBI:	103053548(LIMK2)

PMUR:

107293502(LIMK2)

CTIG:

120297939(LIMK2)

TSR:	106549718(LIMK2)

PGUT:

117677918(LIMK2)

APRI:

131185547(LIMK2)

PTEX:

113447054(LIMK2)

NSS:	113422164(LIMK2)

VKO:	123030452(LIMK2)

PMUA:

114586085(LIMK2)

PRAF:

128403999(LIMK2)

ZVI:	118075674(LIMK2)

HCG:	128338204(LIMK2)

GJA:	107126094(LIMK2)

STOW:

125442784(LIMK2)

EMC:	129341225(LIMK2)

XLA:	108705108(limk2.S) 398298(limk2.L)

XTR:	100216249(limk2)

NPR:	108787789(LIMK2)

RTEM:

120937001(LIMK2)

BBUF:

120988774(LIMK2)

BGAR:

122924405(LIMK2)

MUO:	115480228(LIMK2)

GSH:	117365331(LIMK2)

DRE:	436924(limk2)

SRX:	107741211 107743341

SANH:

107654635 107696070

SGH:	107595948 107597272(limk2)

CCAR:

109074613 109098917

CAUA:

113048881 113075265 113098770

CGIB:

128012702

PTET:

122344885(limk2)

LROH:

127165434(limk2)

OMC:	131541285(limk2)

PPRM:

120469903(limk2)

RKG:	130097102(limk2)

MAMB:

125266455(limk2)

CIDE:

127513235

CERY:

137034186(limk2)

MASI:

127419720 127439632

TROS:

130549798(limk2)

TDW:	130419225(limk2)

MANU:

129439874(limk2)

IPU:

108255496

IFU:	128625421(limk2)

PHYP:

113536929(limk2)

SMEO:

124380440(limk2)

TFD:	113653403(limk2)

TVC:	132854708(limk2)

TRN:	134335617(limk2)

AMEX:

103041870(limk2)

CMAO:

118827577(limk2)

EEE:	113572921(limk2)

TRU:	101073253(limk2)

TFS:	130525594(limk2)

TNG:	GSTEN00029494G001

LCO:	104920331(limk2)

NCC:	104950170(limk2)

TBEN:

117496752(limk2)

CGOB:

115014117(limk2)

PGEO:

117452723(limk2)

GACU:

117561025(limk2)

EMAC:

134873430(limk2)

ELY:	117253123(limk2)

EFO:	125890478(limk2)

PLEP:

121944693(limk2)

SLUC:

116056884(limk2)

ECRA:

117944358(limk2)

ESP:	116688935(limk2)

PFLV:

114556178(limk2)

GAT:	120830253(limk2)

PPUG:

119225365(limk2)

AFB:	129101089(limk2)

CLUM:

117736373(limk2)

PSWI:

130196452(limk2)

MSAM:

119891278(limk2)

SCHU:

122875875(limk2)

CUD:	121510333(limk2)

ALAT:

119020304(limk2)

MZE:	101466306(limk2)

ONL:	100704902(limk2)

OAU:	116332444(limk2)

OLA:	101164484(limk2)

OML:	112148589(limk2)

CSAI:

133450489(limk2)

XMA:	102223521(limk2)

XCO:	114154564(limk2)

XHE:	116729775(limk2)

PRET:

103470304(limk2)

PFOR:

103142854(limk2)

PLAI:

106937175(limk2)

PMEI:

106918102(limk2)

GAF:	122828366(limk2)

PPRL:

129372093(limk2)

CVG:	107091247(limk2)

CTUL:

119790146(limk2)

GMU:	124878025(limk2)

NFU:	107394200(limk2)

KMR:	108234561(limk2)

ALIM:

106521677(limk2)

NWH:	119413367(limk2)

AOCE:

111575831(limk2)

MCEP:

125012141(limk2)

CSEM:

103397254 103398611

POV:	109638189(limk2)

SSEN:

122769907(limk2)

HHIP:

117768245(limk2)

HSP:	118114621(limk2)

PPLT:

128438263(limk2)

SMAU:

118313470(limk2)

LCF:

108878643

SDU:	111226455(limk2)

SLAL:

111660256(limk2)

XGL:	120804925(limk2)

HCQ:	109511502(limk2)

SSCV:

125965829

SBIA:

133499043(limk2)

PEE:	133399770(limk2)

PTAO:

133475483(limk2)

BPEC:

110169779(limk2)

MALB:

109956918(limk2)

BSPL:

114862181(limk2)

SJO:	128365199(limk2)

SASA:

106580321 106584981

STRU:

115164436 115200202

OTW:	112248520 112248521

OMY:	110525730 110536102

OGO:	124034261 124036370

ONE:	115111661 115140111

OKI:	109880552 109894911

OKE:	118358399 118393269

SALP:

111957923 111974246

SNH:	120025885 120063014

CCLU:

121530971 121584904

ELS:	105025609(limk2)

SFM:	108932592(limk2)

PKI:	111839994(limk2)

AANG:

118237555(limk2)

LOC:	102690924 102697124(limk2)

PSPA:

121297129 121299650

ARUT:

117427742 117963060

PSEX:

120540790(limk2)

LCM:	102347674(LIMK2)

CMK:	103190700(limk2)

CRG:

CANU:

MMER:

RPHI:

DPOL:

ATEN:

HSY:

Reference

PMID:10436159

Authors

Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S

Title

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

Journal

Science 285:895-8 (1999)
DOI:10.1126/science.285.5429.895

Reference

PMID:8537403

Authors

Okano I, Hiraoka J, Otera H, Nunoue K, Ohashi K, Iwashita S, Hirai M, Mizuno K

Title

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs.

Journal

J Biol Chem 270:31321-30 (1995)
DOI:10.1074/jbc.270.52.31321

Sequence

[hsa:3985]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (908)   
   KEGG GENES (422)   
   KEGG MGENES (217)   
   RefGene (266)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (922)   

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