KEGG   ORTHOLOGY: K05853Help
Entry
K05853                      KO                                     

Name
ATP2A
Definition
P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04919  Thyroid hormone signaling pathway
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00715  Darier disease
H00755  Acrokeratosis verruciformis
H01129  Brody myopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05853  ATP2A; P-type Ca2+ transporter type 2A
   04024 cAMP signaling pathway
    K05853  ATP2A; P-type Ca2+ transporter type 2A
   04022 cGMP-PKG signaling pathway
    K05853  ATP2A; P-type Ca2+ transporter type 2A
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K05853  ATP2A; P-type Ca2+ transporter type 2A
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K05853  ATP2A; P-type Ca2+ transporter type 2A
   04261 Adrenergic signaling in cardiomyocytes
    K05853  ATP2A; P-type Ca2+ transporter type 2A
  09154 Digestive system
   04972 Pancreatic secretion
    K05853  ATP2A; P-type Ca2+ transporter type 2A
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05853  ATP2A; P-type Ca2+ transporter type 2A
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K05853  ATP2A; P-type Ca2+ transporter type 2A
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K05853  ATP2A; P-type Ca2+ transporter type 2A
   05414 Dilated cardiomyopathy (DCM)
    K05853  ATP2A; P-type Ca2+ transporter type 2A
Enzymes [BR:ko01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     K05853  ATP2A; P-type Ca2+ transporter type 2A
BRITE hierarchy
Other DBs
GO: 0005388
TC: 3.A.3.2
Genes
HSA: 487(ATP2A1) 488(ATP2A2) 489(ATP2A3)
PTR: 100613278(ATP2A3) 452231(ATP2A2) 454019(ATP2A1)
PPS: 100973663 100979248(ATP2A2) 100987290(ATP2A3) 100993633(ATP2A1)
GGO: 101124707(ATP2A3) 101140334(ATP2A2) 101141624(ATP2A1)
PON: 100446409(ATP2A3) 100453755(ATP2A1) 100459692(ATP2A2)
NLE: 100582347(ATP2A1) 100586790(ATP2A3) 100597073(ATP2A2)
MCC: 707768(ATP2A3) 708058(ATP2A1) 710702(ATP2A2)
MCF: 101867165(ATP2A1) 101867359(ATP2A2) 102114913(ATP2A3)
CSAB: 103230269(ATP2A1) 103239106(ATP2A2) 103242172(ATP2A3)
RRO: 104674813(ATP2A2) 104677250(ATP2A3) 104682143(ATP2A1)
RBB: 108520719(ATP2A3) 108523688(ATP2A1) 108534362(ATP2A2)
CJC: 100398261(ATP2A2) 100403358(ATP2A1) 100414635(ATP2A3)
SBQ: 101036977(ATP2A3) 101049289(ATP2A1) 101053869(ATP2A2)
MMU: 11937(Atp2a1) 11938(Atp2a2) 53313(Atp2a3)
MCAL: 110295033(Atp2a2) 110299270(Atp2a1) 110304358(Atp2a3)
MPAH: 110313023(Atp2a2) 110331248(Atp2a3) 110338394(Atp2a1)
RNO: 116601(Atp2a1) 25391(Atp2a3) 29693(Atp2a2)
MUN: 110545322(Atp2a2) 110547949(Atp2a1) 110559262(Atp2a3)
CGE: 100751820(Atp2a2) 100756356(Atp2a3) 100763714(Atp2a1)
NGI: 103726408(Atp2a1) 103739078(Atp2a2) 103751990(Atp2a3)
HGL: 101716306(Atp2a1) 101720630(Atp2a2) 101726683(Atp2a3)
CCAN: 109681722 109681743(Atp2a2) 109683479(Atp2a1) 109694320(Atp2a3)
OCU: 100037716(ATP2A1) 100038308(ATP2A2) 100354976(ATP2A3)
TUP: 102478604(ATP2A3) 102497660 102499870(ATP2A1) 106734944
CFA: 403878(ATP2A2) 479797(ATP2A1) 491437(ATP2A3)
VVP: 112911398(ATP2A3) 112929189(ATP2A1) 112935193(ATP2A2)
AML: 100465047(ATP2A2) 100465699(ATP2A3) 100470716(ATP2A1)
UMR: 103657815(ATP2A1) 103661275(ATP2A2) 103667123(ATP2A3)
UAH: 113266954(ATP2A2) 113267625(ATP2A1) 113269168(ATP2A3)
ORO: 101365162(ATP2A2) 101375916(ATP2A1) 101384489(ATP2A3)
FCA: 101091492(ATP2A1) 101101678(ATP2A3) 493691(ATP2A2)
PTG: 102953307(ATP2A1) 102962973(ATP2A3) 102972450(ATP2A2)
PPAD: 109255119(ATP2A3) 109256497(ATP2A1) 109277669(ATP2A2)
AJU: 106966172(ATP2A1) 106967538(ATP2A2) 106987362(ATP2A3)
BTA: 512313(ATP2A3) 518117(ATP2A1) 540568(ATP2A2)
BOM: 102278227(ATP2A1) 102281077(ATP2A2) 102287572(ATP2A3)
BIU: 109571032(ATP2A2) 109574167(ATP2A3) 109578141(ATP2A1)
BBUB: 102398267(ATP2A3) 102414062(ATP2A1) 102415069(ATP2A2)
CHX: 102174960(ATP2A2) 102180626(ATP2A3) 102187450(ATP2A1)
OAS: 101104344(ATP2A2) 101111207(ATP2A3) 101111766(ATP2A1)
SSC: 100516962(ATP2A1) 396820(ATP2A3) 396875(ATP2A2)
CFR: 102506121(ATP2A2) 102507440(ATP2A1) 102513364(ATP2A3)
CDK: 105095745(ATP2A3) 105102497(ATP2A2) 105102781(ATP2A1)
BACU: 102997251(ATP2A1) 102998569(ATP2A2) 103008249(ATP2A3)
LVE: 103068766(ATP2A2) 103074209(ATP2A3) 103082480(ATP2A1)
OOR: 101283250(ATP2A2) 101283653(ATP2A1) 101284310(ATP2A3)
DLE: 111182199(ATP2A1) 111185895(ATP2A3) 111186914(ATP2A2)
PCAD: 102985121(ATP2A2) 102987197 102987672(ATP2A1) 114487590(ATP2A3)
ECB: 100064403(ATP2A1) 100072684(ATP2A3) 791242(ATP2A2)
EPZ: 103541478(ATP2A2) 103558311(ATP2A3) 103562734(ATP2A1)
EAI: 106825678(ATP2A3) 106829100(ATP2A1) 106842285(ATP2A2)
MYB: 102239308(ATP2A3) 102242162(ATP2A1) 102263136(ATP2A2)
MYD: 102752108(ATP2A2) 102759159(ATP2A1) 102759459(ATP2A3)
MNA: 107528003(ATP2A3) 107529595(ATP2A2) 107541012(ATP2A1)
HAI: 109385859(ATP2A1) 109386055(ATP2A2) 109391912(ATP2A3)
DRO: 112304763(ATP2A1) 112308396(ATP2A3) 112310624(ATP2A2)
PALE: 102884591(ATP2A1) 102885489(ATP2A2) 102885534(ATP2A3)
RAY: 107507669(ATP2A3) 107513235(ATP2A2) 107515804(ATP2A1)
MJV: 108385494(ATP2A1) 108400537(ATP2A2) 108403257 108404162(ATP2A3)
LAV: 100670753(ATP2A2) 100671775(ATP2A3) 100676453(ATP2A1)
MDO: 100014945(ATP2A1) 100015597(ATP2A2) 100619889
SHR: 100918964(ATP2A1) 100922099(ATP2A2) 105750215
PCW: 110193109(ATP2A3) 110196847(ATP2A2) 110222056(ATP2A1)
OAA: 100073740(ATP2A2) 100086258(ATP2A3) 100092580(ATP2A1)
GGA: 395707(ATP2A3) 396446(ATP2A2)
MGP: 100134843(ATP2A3) 100542242(ATP2A2)
CJO: 107307529 107307538 107321126(ATP2A2) 107322650(ATP2A3)
NMEL: 110406283(ATP2A2) 110407860(ATP2A3)
APLA: 101790551(ATP2A3) 101805261(ATP2A2)
TGU: 100222290(ATP2A3) 100227680(ATP2A2) 115497494(ATP2A1)
LSR: 110471764(ATP2A2) 110480028 110481980(ATP2A3) 110484389
SCAN: 103818170(ATP2A2) 103820058(ATP2A3) 103824971
GFR: 102043665(ATP2A3) 102044239(ATP2A2)
FAB: 101815744(ATP2A3) 101816264(ATP2A2)
PHI: 102107999 102112361(ATP2A2) 102112747(ATP2A3)
PMAJ: 107211646(ATP2A2) 107212949(ATP2A3)
CCW: 104688708(ATP2A2) 104691233(ATP2A3)
ETL: 114054945(ATP2A2) 114056692(ATP2A3)
FPG: 101910912 101911529(ATP2A3) 101913094(ATP2A2)
FCH: 102050086(ATP2A2) 102054337(ATP2A3) 102055915
CLV: 102088665(ATP2A2) 102089024 102093008(ATP2A3)
EGZ: 104130108(ATP2A2) 104131892(ATP2A3)
NNI: 104016115(ATP2A3) 104019537(ATP2A2)
ACUN: 113486008(ATP2A2) 113487177(ATP2A3)
PADL: 103912910 103914555(ATP2A2)
AAM: 106487820 106489880(ATP2A1) 106497682(ATP2A2)
ASN: 102371831(ATP2A3) 102377951(ATP2A1) 102382593(ATP2A2)
AMJ: 102563371(ATP2A1) 102563916(ATP2A3) 106736928(ATP2A2)
CMY: 102931905(ATP2A2) 102944712(ATP2A1) 102946899(ATP2A3)
CPIC: 101944337(ATP2A3) 101945463(ATP2A1) 101946777(ATP2A2)
ACS: 100554310(atp2a1) 100554752(atp2a2)
PVT: 110078558(ATP2A1) 110083889(ATP2A2) 110089239
PBI: 103052489(ATP2A1) 103058947(ATP2A2) 103064543 103066784
PMUA: 114581845(ATP2A1) 114585203 114586597(ATP2A2)
GJA: 107107698 107115908(ATP2A2) 107122681(ATP2A1)
XLA: 108704734 108709662 380096(atp2a1.S) 446229(atp2a2.S) 495046 495440(atp2a3.L)
XTR: 100489059(atp2a2) 101733483 613090(atp2a1) 779786(atp2a3)
NPR: 108784529(ATP2A3) 108796871(ATP2A2) 108802336
DRE: 260440(atp2a1) 393940(atp2a2a) 494489(atp2a1l) 562640(si:dkey-28b4.8) 568265(atp2a2b) 568671(atp2a3)
CSEM: 103381587 103383309 103389400 103393216(atp2a1) 103395187(atp2a3) 103397440(atp2a2)
LCM: 102347939 102361733(ATP2A1) 102366698(ATP2A2) 102367479
CMK: 103172296 103184311(atp2a2)
SPU: 581565(SERCA)
APLC: 110980721
SKO: 100375927
DME: Dmel_CG3725(SERCA)
DER: 6548003
DSI: Dsimw501_GD24994(Dsim_GD24994)
DSR: 110191472
DPE: 6589963
DMN: 108158890
DWI: 6640866
DAZ: 108616965
DHE: 111600141
MDE: 101888949
LCQ: 111677027
AGA: AgaP_AGAP006186(ATC1_ANOGA)
AAG: 5568141
AALB: 109425692
AME: 410371
BIM: 100741129
BTER: 100642652
CCAL: 108627416
SOC: 105193852
MPHA: 105832227
AEC: 105150892
ACEP: 105626958
PBAR: 105423295
VEM: 105568972
HST: 105184991
DQU: 106747965
CFO: 105254373
LHU: 105675123
PGC: 109858525
OBO: 105278795
PCF: 106784536
NVI: 100113791
CSOL: 105366631
MDL: 103572062
TCA: 658328
DPA: 109533367
ATD: 109598313
NVL: 108564820
BMOR: 100302733
BMAN: 114249239
PMAC: 106720311
PRAP: 110996853
HAW: 110372527
TNL: 113491725
PXY: 105380420
API: 100167769
DNX: 107170497
AGS: 114131153
RMD: 113555004
BTAB: 109042134
CLEC: 106661308
ZNE: 110828037
FCD: 110851249
TUT: 107366514
DPTE: 113788832
CEL: CELE_K11D9.2(sca-1)
CBR: CBG18305(Cbr-sca-1)
BMY: Bm1_23960
TSP: Tsp_00168
PCAN: 112562356
CRG: 105327139
MYI: 110462070
OBI: 106880767
LAK: 106181601
EPA: 110243970
ADF: 107334467
AMIL: 114960173
PDAM: 113681040
SPIS: 111330080
DGT: 114520348
HMG: 100207814
AQU: 100634808
ATH: AT1G10130(ECA3)
CRB: 17898482
THJ: 104816765
CIT: 102630320
TCC: 18591956
GRA: 105769355
GAB: 108452771
DZI: 111312539
EGR: 104449248
GMX: 100783509
GSJ: 114408778
VRA: 106761867
VAR: 108331647
VUN: 114163916
CCAJ: 109796224
CAM: 101497959
LJA: Lj1g3v1733460.1(Lj1g3v1733460.1)
ADU: 107461122
AIP: 107607959
LANG: 109343853
FVE: 101292079
RCN: 112169882
PPER: 18788384
PMUM: 103320480
PAVI: 110763157
CSV: 101211345
CMO: 103487824
MCHA: 111005059
CMAX: 111496395
CMOS: 111454150
CPEP: 111798583
RCU: 8265280
JCU: 105630831
HBR: 110669858
PEU: 105107602
JRE: 109007860
VVI: 100266003
SLY: 101256303
SPEN: 107025880
SOT: 102595434
CANN: 107847547
NSY: 104211965
NAU: 109241307
INI: 109153030
SIND: 105159092
OEU: 111367656
HAN: 110894822
LSV: 111896562
CCAV: 112502684
DCR: 108199522
SOE: 110796538
NNU: 104608753
OSA: 4333998
DOSA: Os03t0730800-01(Os03g0730800)
OBR: 102701906
BDI: 100844515
ATS: 109751910(LOC109751910)
SBI: 8060530
ZMA: 103643958
SITA: 101781325
PDA: 103707506
EGU: 105055842
MUS: 103988849
DCT: 110100807
PEQ: 110031982
AOF: 109833144
ATR: 18446954
PPP: 112289016
APRO: F751_4008
NCR: NCU03305(nca-1)
NTE: NEUTE1DRAFT72184(NEUTE1DRAFT_72184)
MGR: MGG_04550
SSCK: SPSK_04906
MAW: MAC_00528
MAJ: MAA_07280
CMT: CCM_06967
MBE: MBM_04822
ANI: AN5743.2
ANG: ANI_1_834164(An18g06290)
PBL: PAAG_11170(PAAG_00774)
ABE: ARB_01033
TVE: TRV_02782
PTE: PTT_16365
CNE: CNH02370
CNB: CNBL2380
ABP: AGABI1DRAFT69139(AGABI1DRAFT_69139)
ABV: AGABI2DRAFT183521(AGABI2DRAFT_183521)
MGL: MGL_2215
MRT: MRET_0292
SMIN: v1.2.027964.t1(symbB.v1.2.027964.t1)
TCR: 509777.70
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8825625
  Authors
Zhang Y, Fujii J, Phillips MS, Chen HS, Karpati G, Yee WC, Schrank B, Cornblath DR, Boylan KB, MacLennan DH
  Title
Characterization of cDNA and genomic DNA encoding SERCA1, the Ca(2+)-ATPase of human fast-twitch skeletal muscle sarcoplasmic reticulum, and its elimination as  a candidate gene for Brody disease.
  Journal
Genomics 30:415-24 (1995)
DOI:10.1006/geno.1995.1259
  Sequence
[hsa:487]
Reference
PMID:2844796
  Authors
Lytton J, MacLennan DH
  Title
Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.
  Journal
J Biol Chem 263:15024-31 (1988)
  Sequence
[hsa:488]

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