KEGG   ORTHOLOGY: K05957Help
Entry
K05957                      KO                                     

Name
stsC
Definition
L-glutamine:scyllo-inosose aminotransferase [EC:2.6.1.50]
Pathway
ko00521  Streptomycin biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    K05957  stsC; L-glutamine:scyllo-inosose aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K05957  stsC; L-glutamine:scyllo-inosose aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.50  glutamine---scyllo-inositol transaminase
     K05957  stsC; L-glutamine:scyllo-inosose aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Others
   K05957  stsC; L-glutamine:scyllo-inosose aminotransferase
BRITE hierarchy
Other DBs
RN: R02781
GO: 0047310
Genes
SGR: SGR_5921(stsC)
SGU: SGLAU_01235(stsC)
TaxonomyKoalaUniProt
Reference
PMID:9238101
  Authors
Ahlert J, Distler J, Mansouri K, Piepersberg W
  Title
Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes.
  Journal
Arch Microbiol 168:102-13 (1997)
DOI:10.1007/s002030050475
  Sequence
[sgr:SGR_5921]

KEGG   ENZYME: 2.6.1.50Help
Entry
EC 2.6.1.50                 Enzyme                                 

Name
glutamine---scyllo-inositol transaminase;
glutamine scyllo-inosose aminotransferase;
L-glutamine-keto-scyllo-inositol aminotransferase;
glutamine-scyllo-inosose transaminase;
L-glutamine-scyllo-inosose transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase
Reaction(IUBMB)
L-glutamine + 2,4,6/3,5-pentahydroxycyclohexanone = 2-oxoglutaramate + 1-amino-1-deoxy-scyllo-inositol [RN:R02781]
Reaction(KEGG)
Substrate
L-glutamine [CPD:C00064];
2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691]
Product
2-oxoglutaramate [CPD:C00940];
1-amino-1-deoxy-scyllo-inositol [CPD:C01214]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.50 created 1972
Pathway
ec00521  Streptomycin biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K05957  L-glutamine:scyllo-inosose aminotransferase
Genes
SGR: SGR_5921(stsC)
SGU: SGLAU_01235(stsC)
Taxonomy
Reference
1  [PMID:5781017]
  Authors
Walker JB, Walker MS.
  Title
Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines.
  Journal
Biochemistry 8:763-70 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.50
IUBMB Enzyme Nomenclature: 2.6.1.50
ExPASy - ENZYME nomenclature database: 2.6.1.50
BRENDA, the Enzyme Database: 2.6.1.50
CAS: 9033-03-8

KEGG   REACTION: R02781Help
Entry
R02781                      Reaction                               

Name
L-Glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase
Definition
L-Glutamine + 2,4,6/3,5-Pentahydroxycyclohexanone <=> 2-Oxoglutaramate + 1-Amino-1-deoxy-scyllo-inositol
Equation
Reaction class
RC00006  C00064_C00940
RC00781  C00691_C01214
Enzyme
Pathway
rn00521  Streptomycin biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K05957  L-glutamine:scyllo-inosose aminotransferase [EC:2.6.1.50]
Other DBs
RHEA: 22923

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