KEGG ORTHOLOGY: K06086

ORTHOLOGY: K06086

Entry

K06086                      KO

Symbol

SORBS1, SH3D5, PONSIN, CAP

Name

sorbin and SH3 domain containing protein 1

Pathway

map03320

PPAR signaling pathway

map04517

IgSF CAM signaling

map04520

Adherens junction

map04910

Insulin signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
   03320 PPAR signaling pathway
    K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1

Other DBs

GO:

0005070

Genes

HSA:	10580(SORBS1)

PTR:	450628(SORBS1)

PPS:	100969228(SORBS1)

GGO:	101129717(SORBS1)

PON:	100171946(SORBS1)

PPYG:

129044885(SORBS1)

NLE:	100604923(SORBS1)

HMH:	116456977(SORBS1)

SSYN:

129468634(SORBS1)

MCC:	100424331(SORBS1)

MCF:	102121582(SORBS1)

MTHB:

126962019

MNI:	105478501(SORBS1)

CSAB:

103216309(SORBS1)

CATY:

105581759(SORBS1)

PANU:

101025056(SORBS1)

TGE:	112631285(SORBS1)

MLEU:

105553768(SORBS1)

RRO:	104664673(SORBS1)

RBB:	108543802(SORBS1)

TFN:	117069530(SORBS1)

PTEH:

111538730(SORBS1)

CANG:

105527567(SORBS1)

CJC:	100394064(SORBS1)

SBQ:	101038807(SORBS1)

CIMI:

108295714(SORBS1)

ANAN:

105708135(SORBS1)

CSYR:

103262583(SORBS1)

MMUR:

105872499(SORBS1)

LCAT:

123650348(SORBS1)

ERUF:

138376060(SORBS1)

PCOQ:

105818479(SORBS1)

OGA:	100966763(SORBS1)

MMU:	20411(Sorbs1)

MCAL:

110285633(Sorbs1)

MPAH:

110331176(Sorbs1)

RNO:	686098(Sorbs1)

MCOC:

116103812(Sorbs1)

ANU:	117714347(Sorbs1)

ASYL:

127687552(Sorbs1)

MUN:	110546303(Sorbs1)

CGE:	100755778(Sorbs1)

MAUA:

101841220(Sorbs1)

PROB:

127233398(Sorbs1)

PLEU:

114706896(Sorbs1)

PMAV:

102913006(Sorbs1)

MORG:

121453966(Sorbs1)

MFOT:

126503034

AAMP:

119817058(Sorbs1)

CNL:	130880810(Sorbs1)

NGI:	103733221(Sorbs1)

HGL:	101711592(Sorbs1)

CPOC:

100735801(Sorbs1)

CCAN:

109693652(Sorbs1)

DORD:

105986730(Sorbs1)

DSP:	122115738(Sorbs1)

DMER:

138826163 138836115

PLOP:

125346227(Sorbs1)

NCAR:

124984734

SVUL:

306658764(SORBS1)

MMMA:

107149747(Sorbs1)

ITI:	101957748(Sorbs1)

SCIL:

308633895(SORBS1)

MAVE:

308262424(SORBS1)

OCU:

100353957

OPI:	101523827(SORBS1)

OCZ:	121164296(SORBS1)

TUP:	102499154(SORBS1)

GVR:	103592494(SORBS1)

CFA:	100686806(SORBS1)

CLUD:

112672101(SORBS1)

VVP:	112914048(SORBS1)

VLG:	121485435(SORBS1)

NPO:	129523311(SORBS1)

AML:	100470895(SORBS1)

UMR:	103670991(SORBS1)

UAH:	113251754(SORBS1)

UAR:	123783988(SORBS1)

ELK:

111145157

LLV:

125085006

MPUF:

101687012(SORBS1)

MNP:	132016646(SORBS1)

MLK:	131828617(SORBS1)

NVS:	122900951(SORBS1)

MMAQ:

308354941(SORBS1)

ORO:	101384497(SORBS1)

EJU:	114205335(SORBS1)

ZCA:	113921689(SORBS1)

MLX:	118024044(SORBS1)

MANO:

123846703(SORBS1)

NSU:	110589555(SORBS1)

LWW:

102743494

FCA:	101090050(SORBS1)

PYU:	121037029(SORBS1)

PCOO:

112854556(SORBS1)

PBG:	122493057(SORBS1)

PVIV:

125147866(SORBS1)

LRUF:

124507014

LGF:	123576857(SORBS1)

AJU:

106984799

PTG:	102950366(SORBS1)

PPAD:

109264686(SORBS1)

PUC:

125932824

PLEZ:

122202724(SORBS1)

HHV:	120230581(SORBS1)

CCRU:

144244267(SORBS1)

BTA:	504625(SORBS1)

BOM:	102268819(SORBS1)

BIU:	109579053(SORBS1)

BJV:	133239207(SORBS1)

BBUB:

102390811(SORBS1)

BKE:	129636804(SORBS1)

BBIS:

104983532(SORBS1)

CHX:	102187289(SORBS1)

OAS:	101108178(SORBS1)

OCAN:

138427961(SORBS1)

BTAX:

128067708(SORBS1)

CSUM:

138070146(SORBS1)

ODA:	120873727(SORBS1)

CCAD:

122446097(SORBS1)

MREE:

136160002(SORBS1)

OVR:	110131076(SORBS1)

MBEZ:

129555516(SORBS1)

SSC:	100153151(SORBS1)

CFR:	102522681(SORBS1)

CBAI:

105081805(SORBS1)

CDK:	105084258(SORBS1)

VPC:	102533733(SORBS1)

BACU:

103016925(SORBS1)

BMUS:

118882754(SORBS1)

LVE:	103084862(SORBS1)

OOR:	101282715(SORBS1)

LALB:

132506844(SORBS1)

GMF:	115857815(SORBS1)

DDP:	132439772(SORBS1)

SCOO:

307174926(SORBS1)

DLE:	111172465(SORBS1)

PCAD:

102987677(SORBS1)

PSIU:

116741378(SORBS1)

PPHC:

136135909(SORBS1)

NASI:

112403287(SORBS1)

HAMP:

307058427(SORBS1)

ECB:	100061292(SORBS1)

EPZ:	103555426(SORBS1)

EAI:	106842112(SORBS1)

MYB:	102257912(SORBS1)

MYD:	102753836(SORBS1)

MMYO:

118669929(SORBS1)

MLF:	102438405(SORBS1)

MDT:	132214168(SORBS1)

MYUM:

139021867(SORBS1)

PKL:	118719324(SORBS1)

EFUS:

103288423(SORBS1)

POTS:

308234135(SORBS1)

MNA:	107542565(SORBS1)

DRO:	112307107(SORBS1)

SHON:

118990305(SORBS1)

AJM:	119044503(SORBS1)

PDIC:

114497056(SORBS1)

PHAS:

123828731(SORBS1)

MMF:	118632021(SORBS1)

PPAM:

129077063(SORBS1)

HAI:	109380928(SORBS1)

RFQ:	117035994(SORBS1)

PALE:

102891433(SORBS1)

PGIG:

120609272(SORBS1)

PVP:	105301358(SORBS1)

RAY:	107520386(SORBS1)

MJV:	108386792(SORBS1)

TOD:

119234212

SARA:

101553810(SORBS1)

SFUM:

130029840(SORBS1)

SETR:

126033799(SORBS1)

LAV:	100672319(SORBS1)

TMU:

101347560

ETF:	101652912(SORBS1)

DNM:	101430635(SORBS1)

MDO:	100023075(SORBS1)

GAS:	123238237(SORBS1)

SHR:	100914931(SORBS1)

AFZ:

127551723

PCW:	110215455(SORBS1)

TVP:	118828607(SORBS1)

PBRV:

138169640(SORBS1)

MLAO:

141521112(SORBS1)

OAA:	100074518(SORBS1)

TACU:

119925435(SORBS1)

GGA:	423749(SORBS1)

PCOC:

116235100(SORBS1)

CJO:	107315825(SORBS1)

TPAI:

128077563(SORBS1)

LMUT:

125694059(SORBS1)

NMEL:

110399490(SORBS1)

APLA:

101800303(SORBS1)

AACU:

137859939(SORBS1)

OJA:	118169322(SORBS1)

BCLA:

308446135(SORBS1)

ACYG:

106029990(SORBS1)

ABRC:

308197530(SORBS1)

CATA:

118255570(SORBS1)

AFUL:

116491111(SORBS1)

TGU:	100220298(SORBS1)

LSR:	110480352(SORBS1)

VMC:	128810573(SORBS1)

VCHA:

128791304(SORBS1)

AIB:	137478492(SORBS1)

SCAN:

103813981(SORBS1)

PMOA:

120510949(SORBS1)

OTC:	121336047(SORBS1)

PRUF:

121357069(SORBS1)

ATRC:

139595554(SORBS1)

MAEN:

136559306(SORBS1)

GFR:	102042220(SORBS1)

FAB:	101818518(SORBS1)

OMA:	130255060(SORBS1)

PHI:	102108988(SORBS1)

PMAJ:

107206628(SORBS1)

CCAE:

111931086(SORBS1)

CCW:	104697148(SORBS1)

CBRC:

103624578(SORBS1)

ACOE:

138112397(SORBS1)

ETL:	114065365(SORBS1)

ZAB:	102068248(SORBS1)

ZLE:	135450004(SORBS1)

ACHL:

103810619(SORBS1)

SVG:	106855309(SORBS1)

MMEA:

130579912(SORBS1)

HRT:	120755822(SORBS1)

SATI:

136364244(SORBS1)

CCIC:

134046376(SORBS1)

NNT:	104404836(SORBS1)

SHAB:

115608820(SORBS1)

POCC:

134166647(SORBS1)

FPG:	101918189(SORBS1)

FCH:	102048522(SORBS1)

FRS:	119154092(SORBS1)

CCRI:

104168232(SORBS1)

ACUN:

113481645(SORBS1)

SURA:

141945889(SORBS1)

TALA:

104362213(SORBS1)

ACHC:

115348337(SORBS1)

HALD:

104323881(SORBS1)

HLE:	104831893(SORBS1)

AGEN:

126042545

HHAR:

128146714(SORBS1)

BBUT:

142030162(SORBS1)

GCL:

CSTI:

LDI:

MNB:

DPUB:

104297761(SORBS1)

PPUS:

135176154(SORBS1)

AVIT:

104272904

BRHI:

104495297(SORBS1)

EGZ:	104129116(SORBS1)

NNI:	104020417(SORBS1)

PCRI:

104027243

PCAO:

104041642(SORBS1)

PARX:

142063808(SORBS1)

PADL:

103915571(SORBS1)

AFOR:

103897607(SORBS1)

FGA:

104080689

CBOR:

142084198(SORBS1)

GSTE:

104261803(SORBS1)

CBOY:

140655323(SORBS1)

MAME:

142411317(SORBS1)

CLV:	102098814(SORBS1)

CNIC:

135990618(SORBS1)

NMAY:

308042340(SORBS1)

MUI:	104537099(SORBS1)

PGUU:

104462281(SORBS1)

PLET:

104627351

EHS:	104512421(SORBS1)

CMAC:

104479785(SORBS1)

CUCA:

104060043(SORBS1)

PCUR:

138724000(SORBS1)

TEO:	104383471(SORBS1)

BREG:

104635455(SORBS1)

GAME:

129208517(SORBS1)

OHA:	104335808(SORBS1)

ACAR:

104527906(SORBS1)

CEUR:

306719499(SORBS1)

CPEA:

104391474(SORBS1)

CVF:	104289753(SORBS1)

RTD:	128910950(SORBS1)

CRID:

134517424(SORBS1)

LMIC:

141744483(SORBS1)

NARQ:

141469098(SORBS1)

AAM:	106498913(SORBS1)

AROW:

112961038(SORBS1)

NPD:	112951582(SORBS1)

TGT:	104577467(SORBS1)

DNE:	112980249(SORBS1)

SCAM:

104141779(SORBS1)

ASN:	102376746(SORBS1)

AMJ:	102573792(SORBS1)

CPOO:

109324018(SORBS1)

GGN:	109287399(SORBS1)

CIZ:	142015816(SORBS1)

CMY:	102941012(SORBS1)

CCAY:

125639403(SORBS1)

LKP:	140914593(SORBS1)

NDS:	141990790(SORBS1)

DCC:	119858570(SORBS1)

CPIC:

101943430(SORBS1)

TST:	117881028(SORBS1)

CABI:

116831842(SORBS1)

MRV:	120409590(SORBS1)

EMQ:	137146646(SORBS1)

ACS:	100566321(sorbs1)

ASAO:

132771396(SORBS1)

PVT:	110087242(SORBS1)

SUND:

121925325(SORBS1)

PBI:	103068148(SORBS1)

PMUR:

107285095

CTIG:

120308920(SORBS1)

TSR:

106547180

PGUT:

117676326(SORBS1)

PCAE:

139318616(SORBS1)

APRI:

131201219(SORBS1)

PTEX:

113445434(SORBS1)

NSS:	113415391(SORBS1)

VKO:	123018298(SORBS1)

PMUA:

114596986(SORBS1)

PRAF:

128413634(SORBS1)

ZVI:	118096094(SORBS1)

HCG:	128349885(SORBS1)

GJA:	107106942(SORBS1)

STOW:

125437862(SORBS1)

EMC:	129332821(SORBS1)

XLA:	108696213(sorbs1.L) 108705262

XTR:	100380148(sorbs1)

NPR:	108793509(SORBS1)

RTEM:

120947158(SORBS1)

ACAT:

141106083(SORBS1)

PADS:

140340099(SORBS1)

BBUF:

121004051(SORBS1)

BGAR:

122941601(SORBS1)

DTC:

141098245

PWL:	138300738(SORBS1)

MUO:	115470363(SORBS1)

GSH:	117358634(SORBS1)

DRE:	100002756(sorbs1)

DAES:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:

OMC:

PPRM:

RKG:

SCEP:

307149749(sorbs1)

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:

IFU:

PHYP:

113544990(sorbs1)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

ASAD:

TRU:	101078370(sorbs1)

TFS:

130533449

NCC:

104952747

TBEN:

117499536

CGOB:

115019781(sorbs1)

PGEO:

117459528

GACU:

117552280

EMAC:

134858581

ELY:	117248827(sorbs1)

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

114571656(sorbs1)

GAT:

AFB:

CLUM:

PSWI:

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

PKLU:

LCO:

MZE:	101472571(sorbs1)

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:	102224122(sorbs1)

XCO:	114138298(sorbs1)

XHE:

116712725

PRET:

103477189(sorbs1)

PFOR:

103148272

PLAI:

106936319

PMEI:

106930446(sorbs1)

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

LTU:

MCEP:

AOCE:

EJA:

BFRE:

LCF:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

SDU:

SLAL:

111669502(sorbs1)

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

MALB:

BSPL:

SJO:

SSCO:

TTY:

SASA:

STRU:

OTW:

OMY:

OGO:

ONE:	115113386(sorbs1)

OKI:	109898827(sorbs1)

OKE:

OMM:

OCLA:

SALP:

SNH:

CCLU:

ELS:	105028653(sorbs1)

OEP:

134022434

SFM:	108932831(sorbs1)

PKI:	111860129(sorbs1)

AANG:

118218379

AROT:

135244882

CCOG:

133118571

LOC:	102698616(sorbs1)

PSPA:

121325201

ARUT:

117418209

PSEX:

120516032

LCM:	102346818(SORBS1)

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

LERI:

HAKA:

LRJ:

SKO:

DME:	Dmel_CG18408(CAP)

DER:

6541201

DSI:	Dsimw501_GD10730(Dsim_GD10730)

DYA:	Dyak_GE19353

DAN:

DSR:

DPO:

DMN:

DWI:

DMO:	Dmoj_GI19326

DAZ:

108615795

DNV:

108654036

DHE:

111591923

DVI:	6625753(CAP)

CCAT:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135962206(CAP)

GFS:

ECOE:

CLON:

HIS:

AGA:	1269515 133392064

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ017930

CPII:

CBRI:

BCOO:

LLL:

PPAP:

CFEL:

BMOR:

100307004(CAP)

BMAN:

114239699

MSEX:

115456433

DPL:	KGM_201245

BANY:

112054660

MJU:

123867764

NIQ:

126768858

VCD:	124532248(CAP)

MCIX:

PMAC:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HZE:

TNL:	113500407 113500409

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:	105393136(CAP)

PGW:

126369484

LGLY:

125224634

CSTB:

134743561

CFUM:

141427432(CAP)

TCA:

TMOL:

DPA:

ESIM:

EFOR:

136347269(CAP)

SOY:

115880570

RFG:	143195462(CAP)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

APLN:

PPYR:

OTU:	111421443(CA)

CCRN:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:	139816327(Cap)

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105671996(CAP)

PGC:

109854315

OBO:	105277770(CAP)

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141530443(Cap)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM221180

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:	124160493(LOC124160493)

HAMR:

139686808(CAP)

FCD:

110842791

DPX:	DAPPUDRAFT_197424

DPZ:

AFRA:

TCF:

PVM:

PCHN:

PMOO:

HAME:

CQD:

ESN:

MNZ:

MRJ:

PORN:

OOT:

HAZT:

PPOI:

ISC:

DSV:

DALB:

RSAN:

RMP:	119160726(CAP)

OTI:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PVUL:

GAE:

HASI:

CVN:

YBA:

Reference

PMID:11374898

Authors

Lin WH, Huang CJ, Liu MW, Chang HM, Chen YJ, Tai TY, Chuang LM

Title

Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

Journal

Genomics 74:12-20 (2001)
DOI:10.1006/geno.2001.6541

Sequence

[hsa:10580]

All links

Ontology (1)   
   GO (1)   
Gene (456)   
   MGENES (244)   
   RefGene (209)   
   OC (3)   
All databases (457)   

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