KEGG ORTHOLOGY: K06088

ORTHOLOGY: K06088

Entry

K06088                      KO

Symbol

OCLN

Name

occludin

Pathway

map04514

Cell adhesion molecules

map04530

Tight junction

map04670

Leukocyte transendothelial migration

map05130

Pathogenic Escherichia coli infection

map05160

Hepatitis C

Disease

H00840

Pseudo-TORCH syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06088  OCLN; occludin
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K06088  OCLN; occludin
09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K06088  OCLN; occludin
09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K06088  OCLN; occludin
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06088  OCLN; occludin
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K06088  OCLN; occludin
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K06088  OCLN; occludin

Other DBs

TC:

9.B.41.1

Genes

HSA:	100506658(OCLN)

PTR:	741925(OCLN)

PPS:	100988387(OCLN)

GGO:	101130240(OCLN)

PON:	100174190(OCLN)

PPYG:

129037579(OCLN)

NLE:	100583496(OCLN)

HMH:	116462606(OCLN)

SSYN:

129468023(OCLN)

MCC:	700504(OCLN)

MCF:	102126920(OCLN)

MTHB:

126956536

MNI:	105475186(OCLN)

CSAB:

103222686(OCLN)

CATY:

105599288(OCLN)

PANU:

101012708(OCLN)

TGE:	112626090(OCLN)

MLEU:

105543373(OCLN)

RRO:	104675636(OCLN)

RBB:	108541190(OCLN)

TFN:	117065223(OCLN)

PTEH:

111539901(OCLN)

CANG:

105524161(OCLN)

CJC:	100386012(OCLN)

SBQ:	101052327(OCLN)

CIMI:

108303640(OCLN)

ANAN:

105723831(OCLN)

CSYR:

103270357(OCLN)

MMUR:

105881455(OCLN)

LCAT:

123648628(OCLN)

PCOQ:

105826638(OCLN)

OGA:	100953427(OCLN)

MMU:	18260(Ocln)

MCAL:

110308396(Ocln)

MPAH:

110329108(Ocln)

RNO:	83497(Ocln)

MCOC:

116083458(Ocln)

ANU:	117724046(Ocln)

MUN:	110566803(Ocln)

CGE:	100772862(Ocln)

MAUA:

101837757(Ocln)

PROB:

127220962(Ocln)

PLEU:

114703867(Ocln)

MORG:

121455982(Ocln)

MFOT:

126512540

AAMP:

119809581(Ocln)

NGI:	103738727(Ocln)

HGL:	101704116(Ocln)

CPOC:

100527952(Ocln)

CCAN:

109685696(Ocln)

DORD:

105985341(Ocln)

DSP:	122117361(Ocln)

PLOP:

125367457(Ocln)

NCAR:

124987484

MMMA:

107139425(Ocln) 107159518

OCU:

100338492

OPI:	101520013(OCLN)

TUP:	102476637(OCLN)

GVR:	103592794(OCLN)

CFA:	403844(OCLN)

CLUD:

112660042(OCLN)

VVP:	112906906(OCLN)

VLG:	121498052(OCLN)

NPO:	129513692(OCLN)

AML:	100464895(OCLN)

UMR:	103663872(OCLN)

UAH:	113255249(OCLN)

UAR:	123800219(OCLN)

ELK:

111155304

LLV:

125100100

MPUF:

101679022(OCLN)

MNP:	132028705(OCLN)

MLK:	131832321(OCLN)

NVS:	122918780(OCLN)

ORO:	101378274(OCLN)

EJU:	114198254(OCLN)

ZCA:	113929820(OCLN)

MLX:	118016879(OCLN)

NSU:	110589769(OCLN)

LWW:	102740496(OCLN)

FCA:	101089577(OCLN)

PYU:	121014779(OCLN)

PCOO:

112861118(OCLN)

PBG:	122486776(OCLN)

PVIV:

125172232(OCLN)

LRUF:

124502706

PTG:	102948707(OCLN)

PPAD:

109275040(OCLN)

PUC:

125935714

AJU:

106977078

HHV:	120247935(OCLN)

BTA:	512405(OCLN)

BOM:	102285971(OCLN)

BIU:	109574987(OCLN)

BBUB:

102408658(OCLN)

BBIS:

104998429(OCLN)

CHX:	102185782(OCLN)

OAS:	101118304(OCLN)

BTAX:

128066138(OCLN)

ODA:	120879614(OCLN)

CCAD:

122454265(OCLN)

MBEZ:

129553192(OCLN)

SSC:	397236(OCLN)

CFR:	102524099(OCLN)

CBAI:

105064403(OCLN)

CDK:	105084770(OCLN)

VPC:	102535951(OCLN)

BACU:

103000523(OCLN)

BMUS:

118892372(OCLN)

LVE:	103089356(OCLN)

OOR:	101289239(OCLN)

DLE:	111185810(OCLN)

PCAD:

102986179(OCLN)

PSIU:

116752080(OCLN)

NASI:

112407050(OCLN)

ECB:	100073306(OCLN)

EPZ:	103564224(OCLN)

EAI:	106838052(OCLN)

MYB:	102248373(OCLN)

MYD:	102772867(OCLN)

MMYO:

118655710(OCLN)

MLF:	102421308(OCLN)

MDT:	132233562(OCLN)

PKL:	118702652(OCLN)

EFUS:

103305171(OCLN)

MNA:	107537805(OCLN)

DRO:	112321073(OCLN)

SHON:

118976545(OCLN)

AJM:

119044360

PDIC:

114504333(OCLN)

PHAS:

123824754(OCLN)

MMF:	118641830(OCLN)

PPAM:

129074601(OCLN)

HAI:	109375665(OCLN)

RFQ:	117025106(OCLN)

PALE:

102882809(OCLN)

PGIG:

120608260(OCLN)

PVP:	105300506(OCLN)

RAY:	107498712(OCLN)

MJV:	108384353(OCLN)

TOD:	119260998(OCLN)

SARA:

101537113(OCLN)

SETR:

126001501(OCLN)

LAV:	100657237(OCLN)

TMU:

101344856

ETF:	101653235(OCLN)

DNM:	101445217(OCLN)

MDO:	100014041 100031291(OCLN)

GAS:	123231426(OCLN) 123232205

SHR:	100921400(OCLN) 100925944

AFZ:	127545069 127559047

PCW:	110196112 110216610(OCLN)

TVP:	118830037(OCLN) 118851245

OAA:	100077299(OCLN) 100681791

GGA:	396026(OCLN)

PCOC:

116235753(OCLN)

CJO:	107325447(OCLN)

TPAI:

128088876(OCLN)

LMUT:

125685074(OCLN)

NMEL:

110388986(OCLN)

APLA:

119714189

ACYG:

106047944(OCLN)

CATA:

118259930(OCLN)

AFUL:

116499145(OCLN)

TGU:	115490801(OCLN)

LSR:	110482485(OCLN)

PMOA:

120495702(OCLN)

OTC:

121341438

PRUF:

121359405

GFR:	102033814(OCLN)

OMA:	130264301(OCLN)

PHI:	102109862(OCLN)

ETL:	114071852(OCLN)

ZAB:	102064041(OCLN)

ZLE:	135458959(OCLN)

SVG:	106857034(OCLN)

MMEA:

130584825(OCLN)

HRT:	120748150(OCLN)

FPG:	101916959(OCLN)

FCH:	102058273(OCLN)

NNT:

104405243

SHAB:

115618125(OCLN)

TALA:

116963234 122153655

ACHC:

115349171(OCLN)

HLE:	104829114(OCLN)

AGEN:

126042166

DPUB:

104308330(OCLN)

NNI:	104013674(OCLN)

CLV:	102096634(OCLN)

CUCA:

104065808(OCLN)

CPEA:

104398168(OCLN)

AAM:

106496010

AROW:

112965663(OCLN)

NPD:	112949077(OCLN)

TGT:	104572829(OCLN)

DNE:	112992762(OCLN)

ASN:	102373195 102388289(OCLN)

AMJ:	102562338 106736853(OCLN) 106739579

CPOO:

109308055 109318694

GGN:	109288796 109297288(OCLN)

PSS:	102445570(OCLN)

CMY:	102938809 102940879(OCLN)

CCAY:

125627038 125637206(OCLN)

DCC:	119848460 119856333 119856387

CPIC:

101937217 101940339(OCLN)

TST:	117868887 117879440(OCLN)

CABI:

116818561(OCLN) 116834179

MRV:	120391961 120408328(OCLN)

ACS:	100558258(ocln)

ASAO:

132767097(OCLN) 132781735

PVT:	110072503 110077356(OCLN)

SUND:

121924405(OCLN) 121937068

PBI:	103056104 103067430(OCLN)

PMUR:

107289746(OCLN) 107297372

CTIG:

120297751(OCLN) 120299511

TSR:	106539594 106554770

PGUT:

117670590 117679333(OCLN)

APRI:

131188411 131191140(OCLN)

PTEX:

113447904(OCLN) 113451174

NSS:	113414752(OCLN) 113428890 113429583

VKO:	123018684 123031606(OCLN)

PMUA:

114588448 114606330(OCLN)

PRAF:

128405653 128423731(OCLN)

ZVI:	118076696(OCLN) 118087287

HCG:	128347315(OCLN) 128348198

GJA:	107106651 107112780(OCLN)

STOW:

125432304 125437182(OCLN)

EMC:	129331124 129334508(OCLN) 129336051

XLA:	108713406(ocel1.2.L) 108717687 398133(ocln.S) 431839(ocel1.2.S)

XTR:	548702(ocln) 780218(ocel1.2)

NPR:	108785905 108801653(OCLN)

RTEM:

120909528 120930363(OCLN)

BBUF:

120989397 120990734 120992476(OCLN)

BGAR:

122924693(OCLN) 122931209

MUO:	115463105(OCLN) 115479559

GSH:	117352149(OCLN) 117365609

DRE:	100001136(si:ch73-61d6.3) 405757(oclna) 494075(oclnb) 563016(zgc:154006)

SRX:	107706907 107708750 107718071 107722587 107725329 107744464(ocln) 107751696 107752508 107758028

SANH:

107665009 107665794 107672774 107673430 107680250 107688535 107699027 107704142

SGH:	107548994 107557178 107585150 107589800 107592328 107595017 107598988 107602217

CCAR:

109050807 109089081 109099586

CAUA:

113045891 113049242 113049407 113054735 113091357 113102522 113107191 113110163 113116537

CGIB:

127958535 127963273(si:ch73-61d6.3) 127966826 128010426 128018885 128020854

PTET:

122333827(oclna) 122345401(oclnb) 122351026(si:ch73-61d6.3)

LROH:

127164718(oclnb) 127169845(si:ch73-61d6.3) 127171503(oclna)

OMC:	131541528(oclnb) 131546211(si:ch73-61d6.3) 131548200(oclna)

PPRM:

120469804(oclnb) 120474222(si:ch73-61d6.3) 120483062(oclna) 120483185(zgc:154006)

RKG:	130070744(oclnb) 130075882(oclna) 130091665(si:ch73-61d6.3)

MAMB:

125266695(oclnb) 125279777(si:ch73-61d6.3)

CIDE:

127496877(zgc:154006) 127512096 127517637(si:ch73-61d6.3) 127521262

CERY:

137026907(si:ch73-61d6.3) 137034762(oclnb)

MASI:

127414724 127423709(si:ch73-61d6.3) 127428317 127432853 127433317 127440185

TROS:

130568582(si:ch73-61d6.3)

TDW:	130417303(zgc:154006) 130440419(si:ch73-61d6.3)

MANU:

129414402(si:ch73-61d6.3) 129440070(oclnb) 129446431(oclna)

IPU:	108265315(si:ch73-61d6.3) 128628957

IFU:	128599089(oclnb) 128608248(si:ch73-61d6.3)

PHYP:

113525139 113542585(ocln) 113544773

SMEO:

124380428(oclnb) 124399384(si:ch73-61d6.3)

TFD:	113639733(oclnb) 113648136(si:ch73-61d6.3)

TVC:	132853263(si:ch73-61d6.3) 132854693(oclnb)

TRN:	134318526(si:ch73-61d6.3) 134335134(oclnb)

AMEX:

103026155(si:ch73-61d6.3) 103033778(oclnb) 103041966(oclna)

CMAO:

118814002(si:ch73-61d6.3) 118824271(oclna) 118827333(oclnb)

EEE:	113583516(ocln) 113583961 113587965

CHAR:

105910704(si:ch73-61d6.3) 122131943(oclna)

TRU:	101061452 101066033 101068432 101071307 115247549

TFS:	130529319(si:ch73-61d6.3)

TNG:	GSTEN00007898G001 GSTEN00019295G001 GSTEN00020894G001 GSTEN00025305G001

LCO:	104920958 104921850 104926565 104936935

NCC:	104948062(ocln) 104957385 104957781 104966541

TBEN:

117473025(oclnb) 117476621(oclna) 117488713(zgc:154006) 117496219(si:ch73-61d6.3)

CGOB:

115007601 115013535 115016531 115022882

PGEO:

117445651(si:ch73-61d6.3) 117452170 117452837(oclnb) 117455744(oclna) 117462055(zgc:154006)

GACU:

117532748(zgc:154006) 117541183(oclnb) 117541324(si:ch73-61d6.3) 117551333(oclna)

EMAC:

134868144(oclna) 134869191(si:ch73-61d6.3)

ELY:	117252106(oclnb) 117254192(si:ch73-61d6.3) 117269189(oclna) 117272197(zgc:154006)

EFO:	125890961(oclnb) 125895761(si:ch73-61d6.3)

PLEP:

121960225(oclna) 121964174

SLUC:

116037441(zgc:154006) 116050670(oclnb) 116051015(oclna) 116056284(si:ch73-61d6.3)

ECRA:

117944774(oclnb) 117950596(si:ch73-61d6.3) 117953630(zgc:154006) 117959157(oclna)

ESP:	116675169 116686292 116695320 116699073 116704406

PFLV:

114555785 114561125 114565004 114571035

GAT:	120816388(zgc:154006) 120823854(si:ch73-61d6.3) 120830974(oclnb) 120831724(oclna)

PPUG:

119209252(zgc:154006) 119216405(si:ch73-61d6.3) 119225678(oclnb) 119226391(oclna)

AFB:	129094209 129102261(oclna)

CLUM:

117729798(si:ch73-61d6.3) 117736939(oclnb) 117740940(oclna) 117746803(zgc:154006)

PSWI:

130193537(si:ch73-61d6.3)

MSAM:

119891845(oclnb) 119900452(si:ch73-61d6.3) 119902248(zgc:154006) 119914734(oclna)

SCHU:

122877484(si:ch73-61d6.3)

CUD:	121512612(si:ch73-61d6.3)

ALAT:

119011389(zgc:154006) 119019414(oclnb) 119028698(si:ch73-61d6.3) 119029638(oclna)

MZE:	101467281 101478732 101482283 101486797

ONL:	100695523 100697248 100699711 100709536

OAU:	116313155(oclna) 116314191(oclnb) 116314443(zgc:154006) 116335046(si:ch73-61d6.3)

OLA:	101163521 101163673 101169436 101174753(ocln)

OML:	112137765(oclnb) 112147327(zgc:154006) 112150154(si:ch73-61d6.3) 112163170(oclna)

CSAI:

133458648

XMA:	102217392 102220032 102234134 102237620

XCO:	114146730 114149922 114151508 114155196

XHE:	116721940 116724395 116726359 116729472

PRET:

103463288 103470675 103473229 103479150

PFOR:

103153047 103153363 103155563 103155673

PLAI:

106935196 106947459 106950985 106953034

PMEI:

106906498 106911258 106929301 106929331

GAF:	122819700(oclna) 122839158(si:ch73-61d6.3) 122840517(zgc:154006)

PPRL:

129377681(si:ch73-61d6.3) 129379754(oclna)

CVG:	107093671(ocln) 107094684 107104595 107104778

CTUL:

119774001(zgc:154006) 119774860(oclna) 119784492(si:ch73-61d6.3) 119795599(oclnb)

GMU:	124872332(oclna) 124874281(si:ch73-61d6.3)

NFU:	107392864 107394980 107395740 107396146

KMR:	108238350(si:ch73-61d6.3) 108244843(zgc:154006) 108248907(oclna) 108250728(oclnb)

ALIM:

106516804 106525961 106531758 106536663

NWH:	119413577(oclnb) 119424922(oclna) 119430551

AOCE:

111566876 111570526 111580184 111583376

MCEP:

125009095(si:ch73-61d6.3)

CSEM:

103389949 103394989 103395866 103397131 103397562

POV:	109626335 109633568 109636600 109642577

SSEN:

122758229(oclna) 122780594

HHIP:

117760275(si:ch73-61d6.3) 117767851(oclnb) 117771234(oclna) 117777876(zgc:154006)

HSP:	118120818(si:ch73-61d6.3)

PPLT:

128448537(si:ch73-61d6.3)

SMAU:

118301283(oclna) 118318049(si:ch73-61d6.3)

LCF:	108878001(oclnb) 108896519(si:ch73-61d6.3) 108897636(oclna)

SDU:	111217390 111217842 111228833(ocln) 111228955

SLAL:

111647874(ocln) 111654870 111665999 111671085

XGL:	120790605(si:ch73-61d6.3) 120799196(zgc:154006) 120804737(oclnb) 120806006(oclna)

HCQ:	109507173 109518886 109519004 109532393

SSCV:

125966917(si:ch73-61d6.3) 125993637

SBIA:

133491239(oclna) 133499908(oclnb) 133503660(si:ch73-61d6.3)

PEE:	133400451(oclnb) 133406590(si:ch73-61d6.3) 133413458(oclna)

PTAO:

133464961(oclna) 133473447(oclnb) 133480665(si:ch73-61d6.3)

BPEC:

110167992 110168485 110172330(ocln) 110174815

MALB:

109952175 109959733 109961761 109969352

BSPL:

114845951(marveld2b) 114854229(si:ch73-61d6.3) 114866950(oclna)

SJO:	128362009(si:ch73-61d6.3) 128380698

SASA:

106560577 106567754 106570843(ocln) 106598968

STRU:

115158801 115159703 115169971 115200569(ocln)

OTW:	112220311 112251412(si:ch73-61d6.3) 112262531(oclnb)

OMY:	100462976(oclna) 110508923(zgc:154006) 110524809(si:ch73-61d6.3) 110536432(oclnb)

OGO:	123996589 124036632(oclnb)

ONE:	115103261 115121052 115121355 115122381(ocln)

OKI:	109868828 109872207 109878303(ocln) 109885179

OKE:	118374741(oclnb) 118394134(si:ch73-61d6.3)

SALP:

111961732 111979698 112068935(ocln) 112072511

SNH:	120020491(zgc:154006) 120026058(oclna) 120055050(si:ch73-61d6.3) 120062957(oclnb)

CCLU:

121534106 121534796 121540409

ELS:	105011995 105015140 105024237 105025394(ocln)

SFM:	108921580 108930008 108930510 108938950

PKI:	111847687 111850300 111857775 111860432

AANG:

118212103 118225222 118237286(oclnb)

LOC:	102688329 102695571 102697477(ocln)

PSPA:

121300581 121301410 121306535 121312716

ARUT:

117401256 117403746 117403913 117966204

PSEX:

120532835(oclnb) 120538280

LCM:	102353306(OCLN) 102362150

CMK:	103182021(si:ch73-61d6.3) 103182692(oclnb)

RTP:	109918682(si:ch73-61d6.3)

CPLA:

122558952(oclnb)

HOC:	132822887(oclnb)

PMRN:

116942154 116956002

LRJ:	133343944 133346448(OCLN)

» show all

Reference

PMID:8601611

Authors

Ando-Akatsuka Y, Saitou M, Hirase T, Kishi M, Sakakibara A, Itoh M, Yonemura S, Furuse M, Tsukita S

Title

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues.

Journal

J Cell Biol 133:43-7 (1996)
DOI:10.1083/jcb.133.1.43

Sequence

[hsa:100506658]

Reference

PMID:19114660

Authors

Suzuki T, Elias BC, Seth A, Shen L, Turner JR, Giorgianni F, Desiderio D, Guntaka R, Rao R

Title

PKC eta regulates occludin phosphorylation and epithelial tight junction integrity.

Journal

Proc Natl Acad Sci U S A 106:61-6 (2009)
DOI:10.1073/pnas.0802741106

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Ontology (3)   
   KEGG BRITE (2)   
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Pathway (10)   
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Disease (1)   
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Gene (971)   
   KEGG GENES (709)   
   KEGG MGENES (186)   
   RefGene (74)   
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