KEGG   ORTHOLOGY: K06272
Entry
K06272                      KO                                     
Symbol
ILK
Name
integrin-linked kinase [EC:2.7.11.1]
Pathway
map03320  PPAR signaling pathway
map04360  Axon guidance
map04510  Focal adhesion
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05213  Endometrial cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06272  ILK; integrin-linked kinase
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K06272  ILK; integrin-linked kinase
  09158 Development and regeneration
   04360 Axon guidance
    K06272  ILK; integrin-linked kinase
 09160 Human Diseases
  09162 Cancer: specific types
   05213 Endometrial cancer
    K06272  ILK; integrin-linked kinase
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K06272  ILK; integrin-linked kinase
   05100 Bacterial invasion of epithelial cells
    K06272  ILK; integrin-linked kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06272  ILK; integrin-linked kinase
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06272  ILK; integrin-linked kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06272  ILK; integrin-linked kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: TKL group
  MLK family
   K06272  ILK; integrin-linked kinase
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    K06272  ILK; integrin-linked kinase
Genes
HSA: 3611(ILK)
PTR: 748941(ILK)
PPS: 100968361(ILK)
GGO: 101148955(ILK)
PON: 100173674(ILK)
NLE: 100598379(ILK)
HMH: 116476577(ILK)
MCC: 709944(ILK)
MCF: 102126017(ILK)
MTHB: 126935076
MNI: 105488694(ILK)
CSAB: 103241301(ILK)
CATY: 105575040(ILK)
PANU: 103877691(ILK)
TGE: 112606152(ILK)
MLEU: 105533899(ILK)
RRO: 104678304(ILK)
RBB: 108543237(ILK)
TFN: 117081027(ILK)
PTEH: 111524650(ILK)
CANG: 105520547(ILK)
CJC: 100406751(ILK)
SBQ: 101029493(ILK)
CIMI: 108288320(ILK)
CSYR: 103257950(ILK)
MMUR: 105883444(ILK)
LCAT: 123642363(ILK)
PCOQ: 105818382(ILK)
OGA: 100958529(ILK)
MMU: 16202(Ilk)
MCAL: 110299376(Ilk)
MPAH: 110335784(Ilk)
RNO: 170922(Ilk)
MCOC: 116102736(Ilk)
ANU: 117707752(Ilk)
MUN: 110559582(Ilk)
CGE: 100689388(Ilk)
MAUA: 101844354(Ilk)
PROB: 127228103(Ilk)
PLEU: 114683843(Ilk)
MORG: 121457500(Ilk)
MFOT: 126494103
AAMP: 119824629(Ilk)
NGI: 103737567(Ilk)
HGL: 101706216(Ilk)
CPOC: 100135559(Ilk)
CCAN: 109696308(Ilk)
DORD: 106000378(Ilk)
DSP: 122117655(Ilk)
NCAR: 124958328
OCU: 100355759
OPI: 101516762(ILK)
TUP: 102473651(ILK)
GVR: 103597703(ILK)
CFA: 476836(ILK)
CLUD: 112667559(ILK)
VVP: 112910864(ILK)
VLG: 121475977(ILK)
AML: 100473650(ILK)
UMR: 103681403(ILK)
UAH: 113245818(ILK)
UAR: 123782737(ILK)
LLV: 125078222
MPUF: 101674249(ILK)
NVS: 122912679(ILK)
ORO: 101363175(ILK) 101375473
EJU: 114219330(ILK)
ZCA: 113915229(ILK) 113927937
MLX: 118000764 118004254(ILK)
NSU: 110576525(ILK)
LWW: 102744007(ILK)
FCA: 101092790(ILK)
PYU: 121021126(ILK)
PCOO: 112865342(ILK)
PBG: 122483502(ILK)
PTG: 102967313(ILK)
PPAD: 109261635 109271076(ILK)
PUC: 125936751
AJU: 106981151(ILK)
HHV: 120221442(ILK)
BTA: 540207(ILK)
BOM: 102280066(ILK)
BIU: 109569757(ILK)
BBUB: 102403164(ILK)
BBIS: 104987993(ILK)
CHX: 102177259(ILK)
OAS: 100913157(ILK)
ODA: 120876543(ILK)
CCAD: 122449497(ILK)
SSC: 100623256(ILK)
CFR: 102511818(ILK)
CBAI: 105076687(ILK)
CDK: 105097907(ILK)
VPC: 102537970(ILK)
BACU: 103018082(ILK)
LVE: 103083507(ILK)
OOR: 101289017(ILK)
DLE: 111169176(ILK)
PCAD: 102995328(ILK)
PSIU: 116758733(ILK)
NASI: 112407651(ILK)
ECB: 100070066(ILK)
EPZ: 103553532(ILK)
EAI: 106838181(ILK)
MYB: 102248130(ILK)
MYD: 102764668(ILK)
MMYO: 118664767(ILK)
MLF: 102419059(ILK)
MNA: 107540507(ILK)
PKL: 118712967(ILK)
HAI: 109376531(ILK)
DRO: 112312782(ILK)
SHON: 118990814(ILK)
AJM: 119041221(ILK)
PDIC: 114500412(ILK)
PHAS: 123819215(ILK)
MMF: 118616774(ILK)
RFQ: 117030581(ILK)
PALE: 102887513(ILK)
PGIG: 120590232(ILK)
PVP: 105309085(ILK)
RAY: 107504363(ILK)
MJV: 108384232(ILK)
TOD: 119255543(ILK)
SARA: 101542545(ILK)
LAV: 100666830(ILK)
TMU: 101346618
ETF: 101652908(ILK)
DNM: 101430574(ILK)
MDO: 100023322(ILK)
GAS: 123240475(ILK)
SHR: 100915068(ILK)
AFZ: 127555379
PCW: 110200481(ILK)
OAA: 114807332(ILK)
GGA: 374018(ILK)
PCOC: 116239525(ILK)
MGP: 100548319(ILK)
CJO: 107308571(ILK)
NMEL: 110391748(ILK)
APLA: 101790559(ILK)
ACYG: 106049775(ILK)
AFUL: 116501897(ILK)
TGU: 100228455(ILK)
LSR: 110474957(ILK)
SCAN: 103824410(ILK)
PMOA: 120499971(ILK)
OTC: 121334219(ILK)
PRUF: 121355145(ILK)
GFR: 102034600(ILK)
FAB: 101806205(ILK)
PHI: 102104711(ILK)
PMAJ: 107198962(ILK)
CCAE: 111943737(ILK)
CCW: 104698082(ILK)
CBRC: 103624045(ILK)
ETL: 114069902(ILK)
SVG: 106861767(ILK)
FPG: 101919060(ILK)
FCH: 102050186(ILK)
CLV: 102094280(ILK)
EGZ: 104130615(ILK)
NNI: 104014876(ILK)
PLET: 104625549(ILK)
PCAO: 104052487(ILK)
TALA: 116962859(ILK)
PADL: 103924867(ILK)
AFOR: 103901135(ILK)
ACHC: 115353222(ILK)
HALD: 104313323(ILK)
HLE: 104837527(ILK)
AGEN: 126048323
GCL: 127019848
CCRI: 104157490(ILK)
GSTE: 104256784(ILK)
OHA: 104328434(ILK)
SHAB: 115602354(ILK)
DPUB: 104302339(ILK)
CPEA: 104385373(ILK)
CVF: 104284863(ILK)
CUCA: 104065403(ILK)
TEO: 104375742(ILK)
AAM: 106497742 106497745(ILK)
AROW: 112964941(ILK)
NPD: 112955056(ILK)
TGT: 104580293(ILK)
DNE: 112993499(ILK)
SCAM: 104148979(ILK)
ASN: 102378418(ILK)
AMJ: 102559647(ILK)
CPOO: 109305564(ILK)
GGN: 109303308(ILK)
PSS: 102443361(ILK)
CMY: 102931035(ILK)
CPIC: 101952498(ILK)
CABI: 116818167(ILK)
MRV: 120399168(ILK)
ACS: 100556484(ilk)
PVT: 110078157(ILK)
SUND: 121926893(ILK)
PBI: 103059609(ILK)
PMUR: 107288657(ILK)
CTIG: 120310060(ILK)
TSR: 106541883(ILK)
PGUT: 117670870(ILK)
VKO: 123022453(ILK)
PMUA: 114595166(ILK)
ZVI: 118084895(ILK)
HCG: 128350067(ILK)
GJA: 107116953(ILK)
STOW: 125431774(ILK)
XLA: 444414 446640(ilk.S)
XTR: 100145644(ilk)
NPR: 108799886(ILK)
RTEM: 120928861(ILK)
BBUF: 120996657(ILK)
BGAR: 122932397(ILK)
DRE: 393543(ilk)
SANH: 107685015 107701121(ilk)
SGH: 107556859(ilk)
PPRM: 120482554(ilk)
MAMB: 125258610(ilk)
CIDE: 127520263
IPU: 108277251(ilk)
PHYP: 113543442(ilk)
SMEO: 124393556(ilk)
TFD: 113645779(ilk)
AMEX: 103042782(ilk)
EEE: 113581672(ilk)
TRU: 101064916(ilk) 101074511
NCC: 104947434 104952256(ilk)
CGOB: 115018208(ilk) 115018869
ELY: 117259759 117262586(ilk)
EFO: 125888378 125898804(ilk)
PLEP: 121943289 121952817(ilk)
SLUC: 116048464 116065003(ilk)
ECRA: 117941692 117955821(ilk)
ESP: 116671424(ilk) 116701018
PFLV: 114552620(ilk) 114567223
GAT: 120822407(ilk) 120829500
PPUG: 119215937(ilk) 119217678
MSAM: 119882724 119895407(ilk)
CUD: 121518875(ilk) 121521052
ALAT: 119005623 119031887(ilk)
MZE: 101477640 101485551(ilk)
OAU: 116331456(ilk) 116335685
OML: 112142591(ilk) 112149471
XMA: 102225759(ilk) 102231522
XCO: 114133688(ilk) 114152747
XHE: 116707863(ilk) 116727825
PRET: 103474125 103475517(ilk)
PFOR: 103140564(ilk) 103148510
PLAI: 106957611(ilk) 106960551
PMEI: 106905085 106914113(ilk)
GAF: 122832365 122845253(ilk)
CVG: 107087916 107099544(ilk)
CTUL: 119783484(ilk) 119795397
GMU: 124876711(ilk) 124883803
KMR: 108235923 108236879(ilk)
ALIM: 106514119(ilk) 106529737
NWH: 119410707(ilk)
MCEP: 125013895 125021750(ilk)
CSEM: 103378043(ilk) 103395087
SSEN: 122773240 122780136(ilk)
HHIP: 117772891 117774583(ilk)
HSP: 118106044 118122525(ilk)
LCF: 108876077 108893604(ilk)
SLAL: 111653646(ilk) 111666302
XGL: 120792390 120803000(ilk)
HCQ: 109509738 109527221(ilk)
BSPL: 114867715 114869209(ilk)
SASA: 100194973(ilk) 106581335
ELS: 105023567(ilk)
SFM: 108921298(ilk) 108938337
PKI: 111838003 111856818(ilk)
AANG: 118209593 118235628(ilk)
LOC: 102684116(ilk)
PSPA: 121320427(ilk) 121327760
PSEX: 120523078(ilk)
LCM: 102365370(ILK)
CPLA: 122551091(ilk)
BFO: 118419011
BBEL: 109477568
CIN: 100184368
APLC: 110979821
AJC: 117112795
SKO: 100376887
DME: Dmel_CG10504(Ilk)
DER: 6546273
DSE: 6616413
DSI: Dsimw501_GD14943(Dsim_GD14943)
DAN: 6506935
DSR: 110189984
DPO: 4813879
DPE: 6601164
DMN: 108153196
DWI: 6639079
DGR: 6557157
DAZ: 108613105
DNV: 108651892
DHE: 111594364
DVI: 6623860
CCAT: 101454155
BOD: 106627380
MDE: 101895541
SCAC: 106091487
LCQ: 111683614
LSQ: 119613940
HIS: 119648093
ACOZ: 120952924
AARA: 120897949
AMER: 121593631
ASTE: 118514386
AAG: 5575137
AALB: 109400747
CPII: 120420657
CNS: 116345695
BCOO: 119077300
AME: 413354
ACER: 107993213
ALAB: 122719036
BIM: 100740129
BBIF: 117213316
BVK: 117235061
BVAN: 117158691
BTER: 100646980
BPYO: 122569093
CCAL: 108631300
OBB: 114878048
MGEN: 117224227
NMEA: 116424261
CGIG: 122402605
SOC: 105200508
MPHA: 105831508
AEC: 105145197
ACEP: 105617817
PBAR: 105424315
VEM: 105568674
HST: 105184315
DQU: 106745964
CFO: 105256339
FEX: 115235303
LHU: 105680032
PGC: 109857075
OBO: 105284326
PCF: 106790583
PFUC: 122523647
VPS: 122629973
NVI: 100116422
CSOL: 105362293
TPRE: 106650856
MDL: 103572637
CGLO: 123266672
FAS: 105273336
DAM: 107048485
AGIF: 122856830
CINS: 118068530
LHT: 122499139
CCIN: 107269960
TCA: 655116
DPA: 109544881
SOY: 115886595
ATD: 109599023
CSET: 123310407
AGB: 108909905
LDC: 111518201
NVL: 108565932
APLN: 108736244
PPYR: 116173899
OTU: 111428636
BMOR: 101744627
MSEX: 115450105
BANY: 112046277
NIQ: 126774470
PMAC: 106718907
PPOT: 106100288
PXU: 106121458
PRAP: 110995055
PBX: 123710029
PNAP: 125048770
CCRC: 123694508
HAW: 110373704
HZE: 124635433
TNL: 113497766
SLIU: 111358816
OFU: 114362824
API: 100163230
AGS: 114132415
RMD: 113551346
BTAB: 109040825
DCI: 103518146
CLEC: 106664613
HHAL: 106682131
NLU: 111056781
FOC: 113210784
TPAL: 117653502
ZNE: 110836773
CSEC: 111866320
SGRE: 126266971
FCD: 110851117
DMK: 116921821
DPZ: 124316309
PVM: 113807347
PJA: 122244595
PCHN: 125033325
PMOO: 119578071
HAME: 121856003
PCLA: 123746414
PTRU: 123510073
ESN: 126996080
HAZT: 108676321
EAF: 111696799
LSM: 121126759
PPOI: 119091720
DSV: 119449858
RSAN: 119382762
RMP: 119170105
VDE: 111249024
VJA: 111266001
TUT: 107364041
DPTE: 113788984
DFR: 124490475
CSCU: 111640873
PTEP: 107453285
SDM: 118205263
CEL: CELE_C29F9.7(pat-4)
CBR: CBG_15792(Cbr-pat-4)
BMY: BM_BM2471(Bma-pat-4)
PCAN: 112558900
BGT: 106064600
GAE: 121376478
HRF: 124146977
HRJ: 124283083
CRG: 105340380
MYI: 110440402
PMAX: 117328918
MCAF: 127716435
MMER: 123557186
DPOL: 127876100
OBI: 106868884
OSN: 115222698
LAK: 106165827
SHX: MS3_00005632(PAT4)
EGL: EGR_02061
ATEN: 116295763
ADF: 107342551
AMIL: 114965495
PDAM: 113670668
SPIS: 111339027
XEN: 124446436
HMG: 100210366
AQU: 100634569
CPAP: 110807510
CIT: 102618062
PVY: 116111241
MINC: 123197141
TCC: 18590140
GRA: 105797919
GHI: 107943974
GAB: 108455533
DZI: 111284273
EGR: 104423692
FVE: 101311832
RCN: 112165997
PPER: 18782708
PMUM: 103328659
PAVI: 110772024
PDUL: 117623194
MDM: 103405799
PXB: 103933348
ZJU: 107417087
MNT: 21409748
RCU: 8265009
JCU: 105650432
HBR: 110658997
MESC: 110608500
POP: 18099408
PEU: 105123450
TWL: 119988730
VVI: 100852545
VRI: 117929889
SLY: 101249145
SPEN: 107009611
SOT: 102602873
SSTN: 125847597
NSY: 104245839
NTO: 104095079
NAU: 109234245
INI: 109151235
ITR: 116021169
SIND: 105176138
OEU: 111367371
EGT: 105953412
APAN: 127241979
HAN: 110887685
ECAD: 122588177
LSV: 111909966
CCAV: 112515719
DCR: 108210573
CSIN: 114315159
AOF: 109829103
ATR: 105420183
SPAR: SPRG_21119
 » show all
Reference
PMID:8538749
  Authors
Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S
  Title
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.
  Journal
Nature 379:91-6 (1996)
DOI:10.1038/379091a0
  Sequence
[hsa:3611]
Reference
  Authors
Fielding AB, Dobreva I, Dedhar S
  Title
Beyond focal adhesions: integrin-linked kinase associates with tubulin and regulates mitotic spindle organization.
  Journal
Cell Cycle 7:1899-906 (2008)
DOI:10.4161/cc.7.13.6204

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